Harsh B. Pathak, Ph.D. - Publications

2006 Pennsylvania State University, State College, PA, United States 
Microbiology Biology, Molecular Biology, Virology Biology

21/37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Pathak HB, Zhou Y, Sethi G, Hirst J, Schilder RJ, Golemis EA, Godwin AK. A Synthetic Lethality Screen Using a Focused siRNA Library to Identify Sensitizers to Dasatinib Therapy for the Treatment of Epithelial Ovarian Cancer. Plos One. 10: e0144126. PMID 26637171 DOI: 10.1371/Journal.Pone.0144126  0.64
2015 Rebbeck TR, Mitra N, Wan F, Sinilnikova OM, Healey S, McGuffog L, Mazoyer S, Chenevix-Trench G, Easton DF, Antoniou AC, Nathanson KL, Laitman Y, Kushnir A, Paluch-Shimon S, ... ... Pathak H, et al. Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer. Jama. 313: 1347-61. PMID 25849179 DOI: 10.1001/Jama.2014.5985  0.64
2014 Sethi G, Kwon Y, Burkhalter RJ, Pathak HB, Madan R, McHugh S, Atay S, Murthy S, Tawfik OW, Godwin AK. PTN signaling: Components and mechanistic insights in human ovarian cancer. Molecular Carcinogenesis. PMID 25418856 DOI: 10.1002/Mc.22249  0.64
2014 Fang CY, Ross EA, Pathak HB, Godwin AK, Tseng M. Acculturative stress and inflammation among Chinese immigrant women. Psychosomatic Medicine. 76: 320-6. PMID 24846001 DOI: 10.1097/PSY.0000000000000065  0.64
2014 Do TV, Xiao F, Bickel LE, Klein-Szanto AJ, Pathak HB, Hua X, Howe C, O'Brien SW, Maglaty M, Ecsedy JA, Litwin S, Golemis EA, Schilder RJ, Godwin AK, Connolly DC. Aurora kinase A mediates epithelial ovarian cancer cell migration and adhesion. Oncogene. 33: 539-49. PMID 23334327 DOI: 10.1038/Onc.2012.632  0.64
2012 Sethi G, Pathak HB, Zhang H, Zhou Y, Einarson MB, Vathipadiekal V, Gunewardena S, Birrer MJ, Godwin AK. An RNA interference lethality screen of the human druggable genome to identify molecular vulnerabilities in epithelial ovarian cancer. Plos One. 7: e47086. PMID 23056589 DOI: 10.1371/Journal.Pone.0047086  0.64
2012 Schilder RJ, Brady WE, Lankes HA, Fiorica JV, Shahin MS, Zhou XC, Mannel RS, Pathak HB, Hu W, Alpaugh RK, Sood AK, Godwin AK. Phase II evaluation of dasatinib in the treatment of recurrent or persistent epithelial ovarian or primary peritoneal carcinoma: a Gynecologic Oncology Group study. Gynecologic Oncology. 127: 70-4. PMID 22710075 DOI: 10.1016/j.ygyno.2012.06.009  0.64
2012 Stevens KN, Fredericksen Z, Vachon CM, Wang X, Margolin S, Lindblom A, Nevanlinna H, Greco D, Aittomäki K, Blomqvist C, Chang-Claude J, Vrieling A, Flesch-Janys D, Sinn HP, Wang-Gohrke S, ... ... Pathak HB, et al. 19p13.1 is a triple-negative-specific breast cancer susceptibility locus. Cancer Research. 72: 1795-803. PMID 22331459 DOI: 10.1158/0008-5472.Can-11-3364  0.64
2012 Ratushny V, Pathak HB, Beeharry N, Tikhmyanova N, Xiao F, Li T, Litwin S, Connolly DC, Yen TJ, Weiner LM, Godwin AK, Golemis EA. Dual inhibition of SRC and Aurora kinases induces postmitotic attachment defects and cell death. Oncogene. 31: 1217-27. PMID 21785464 DOI: 10.1038/Onc.2011.314  0.64
2011 Sasaroli D, Gimotty PA, Pathak HB, Hammond R, Kougioumtzidou E, Katsaros D, Buckanovich R, Devarajan K, Sandaltzopoulos R, Godwin AK, Scholler N, Coukos G. Novel surface targets and serum biomarkers from the ovarian cancer vasculature. Cancer Biology & Therapy. 12: 169-80. PMID 21617380 DOI: 10.4161/Cbt.12.3.16260  0.64
2009 Oh HS, Pathak HB, Goodfellow IG, Arnold JJ, Cameron CE. Insight into poliovirus genome replication and encapsidation obtained from studies of 3B-3C cleavage site mutants. Journal of Virology. 83: 9370-87. PMID 19587035 DOI: 10.1128/Jvi.02076-08  0.64
2009 Schilder RJ, Pathak HB, Lokshin AE, Holloway RW, Alvarez RD, Aghajanian C, Min H, Devarajan K, Ross E, Drescher CW, Godwin AK. Phase II trial of single agent cetuximab in patients with persistent or recurrent epithelial ovarian or primary peritoneal carcinoma with the potential for dose escalation to rash. Gynecologic Oncology. 113: 21-7. PMID 19162309 DOI: 10.1200/Jco.2007.25.18_Suppl.5577  0.64
2008 Pathak HB, Oh HS, Goodfellow IG, Arnold JJ, Cameron CE. Picornavirus genome replication: roles of precursor proteins and rate-limiting steps in oriI-dependent VPg uridylylation. The Journal of Biological Chemistry. 283: 30677-88. PMID 18779320 DOI: 10.1074/Jbc.M806101200  0.64
2008 Shen M, Reitman ZJ, Zhao Y, Moustafa I, Wang Q, Arnold JJ, Pathak HB, Cameron CE. Picornavirus genome replication. Identification of the surface of the poliovirus (PV) 3C dimer that interacts with PV 3Dpol during VPg uridylylation and construction of a structural model for the PV 3C2-3Dpol complex. The Journal of Biological Chemistry. 283: 875-88. PMID 17993457 DOI: 10.1074/Jbc.M707907200  0.64
2007 Shen M, Wang Q, Yang Y, Pathak HB, Arnold JJ, Castro C, Lemon SM, Cameron CE. Human rhinovirus type 14 gain-of-function mutants for oriI utilization define residues of 3C(D) and 3Dpol that contribute to assembly and stability of the picornavirus VPg uridylylation complex. Journal of Virology. 81: 12485-95. PMID 17855535 DOI: 10.1128/Jvi.00972-07  0.64
2007 Pathak HB, Arnold JJ, Wiegand PN, Hargittai MR, Cameron CE. Picornavirus genome replication: assembly and organization of the VPg uridylylation ribonucleoprotein (initiation) complex. The Journal of Biological Chemistry. 282: 16202-13. PMID 17392285 DOI: 10.1074/Jbc.M610608200  0.64
2007 Marcotte LL, Wass AB, Gohara DW, Pathak HB, Arnold JJ, Filman DJ, Cameron CE, Hogle JM. Crystal structure of poliovirus 3CD protein: virally encoded protease and precursor to the RNA-dependent RNA polymerase. Journal of Virology. 81: 3583-96. PMID 17251299 DOI: 10.1128/Jvi.02306-06  0.64
2005 Franco D, Pathak HB, Cameron CE, Rombaut B, Wimmer E, Paul AV. Stimulation of poliovirus RNA synthesis and virus maturation in a HeLa cell-free in vitro translation-RNA replication system by viral protein 3CDpro. Virology Journal. 2: 86. PMID 16300678 DOI: 10.1186/1743-422X-2-86  0.64
2005 Franco D, Pathak HB, Cameron CE, Rombaut B, Wimmer E, Paul AV. Stimulation of poliovirus synthesis in a HeLa cell-free in vitro translation-RNA replication system by viral protein 3CDpro. Journal of Virology. 79: 6358-67. PMID 15858019 DOI: 10.1128/Jvi.79.10.6358-6367.2005  0.64
2002 Pathak HB, Ghosh SK, Roberts AW, Sharma SD, Yoder JD, Arnold JJ, Gohara DW, Barton DJ, Paul AV, Cameron CE. Structure-function relationships of the RNA-dependent RNA polymerase from poliovirus (3Dpol). A surface of the primary oligomerization domain functions in capsid precursor processing and VPg uridylylation. The Journal of Biological Chemistry. 277: 31551-62. PMID 12077141 DOI: 10.1074/Jbc.M204408200  0.64
2001 Wei L, Huhn JS, Mory A, Pathak HB, Sosnovtsev SV, Green KY, Cameron CE. Proteinase-polymerase precursor as the active form of feline calicivirus RNA-dependent RNA polymerase. Journal of Virology. 75: 1211-9. PMID 11152494 DOI: 10.1128/Jvi.75.3.1211-1219.2001  0.64
Low-probability matches
2021 Gupta VG, Hirst J, Petersen S, Roby KF, Kusch M, Zhou H, Clive ML, Jewell A, Pathak HB, Godwin AK, Wilson AJ, Crispens MA, Cybulla E, Vindigni A, Fuh KC, et al. Entinostat, a selective HDAC1/2 inhibitor, potentiates the effects of olaparib in homologous recombination proficient ovarian cancer. Gynecologic Oncology. PMID 33867143 DOI: 10.1016/j.ygyno.2021.04.015  0.01
2021 Sharma P, Abramson VG, O'Dea AP, Nye L, Mayer IA, Pathak HB, Hoffmann M, Stecklein SR, Elia M, Lewis S, Scott J, De Jong JA, Wang YY, Yoder R, Schwensen K, et al. Clinical and biomarker results from phase I/II study of PI3K inhibitor alpelisib plus nab-paclitaxel in HER2-negative metastatic breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 33602685 DOI: 10.1158/1078-0432.CCR-20-4879  0.01
2021 Li M, Soder R, Abhyankar S, Abdelhakim H, Braun MW, Trinidad CV, Pathak HB, Pessetto Z, Deighan C, Ganguly S, Dawn B, McGuirk J, Dunavin N, Godwin AK. WJMSC-derived small extracellular vesicle enhance T cell suppression through PD-L1. Journal of Extracellular Vesicles. 10: e12067. PMID 33598108 DOI: 10.1002/jev2.12067  0.01
2021 Dimachkie MD, Bechtel MD, Robertson HL, Michel C, Lee EK, Sullivan DK, Chalise P, Thrasher JB, Parker WP, Godwin AK, Pathak HB, DiGiovanni J, Shivappa N, Hébert JR, Hamilton-Reeves JM. Exploration of biomarkers from a pilot weight management study for men undergoing radical prostatectomy. Urologic Oncology. PMID 33563536 DOI: 10.1016/j.urolonc.2021.01.010  0.01
2020 Braun MW, Abdelhakim H, Li M, Hyter S, Pessetto Z, Koestler DC, Pathak HB, Dunavin N, Godwin AK. Adherent cell depletion promotes the expansion of renal cell carcinoma infiltrating T cells with optimal characteristics for adoptive transfer. Journal For Immunotherapy of Cancer. 8. PMID 33037114 DOI: 10.1136/jitc-2020-000706  0.01
2020 Park GY, Pathak HB, Godwin AK, Kwon Y. Epithelial-stromal communication via CXCL1-CXCR2 interaction stimulates growth of ovarian cancer cells through p38 activation. Cellular Oncology (Dordrecht). PMID 32910411 DOI: 10.1007/s13402-020-00554-0  0.01
2020 Sharma P, Rodler E, Barlow WE, Gralow J, Huggins-Puhalla SL, Anders CK, Goldstein LJ, Brown-Glaberman UA, Huynh T, Szyarto CS, Godwin AK, Pathak HB, Swisher EM, Radke MR, Timms KM, et al. Results of a phase II randomized trial of cisplatin +/- veliparib in metastatic triple-negative breast cancer (TNBC) and/or germline BRCA-associated breast cancer (SWOG S1416). Journal of Clinical Oncology. 38: 1001-1001. DOI: 10.1200/jco.2020.38.15_suppl.1001  0.01
2019 Sharma P, Barlow WE, Godwin AK, Parkes EE, Knight LA, Walker SM, Kennedy RD, Harkin DP, Logan GE, Steele CJ, Lambe SM, Badve S, Gökmen-Polar Y, Pathak HB, Isakova K, et al. Validation of the DNA Damage Immune Response Signature in Patients With Triple-Negative Breast Cancer From the SWOG 9313c Trial. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO1900693. PMID 31657982 DOI: 10.1200/Jco.19.00693  0.01
2019 Fang CY, Egleston BL, Byrne C, Bohr GS, Pathak HB, Godwin AK, Siu PT, Tseng M. Inflammation and breast density among female Chinese immigrants: exploring variations across neighborhoods. Cancer Causes & Control : Ccc. PMID 31392546 DOI: 10.1007/S10552-019-01206-X  0.01
2018 Hirst J, Pathak HB, Hyter S, Pessetto ZY, Ly T, Graw S, Koestler DC, Krieg AJ, Roby KF, Godwin AK. Licofelone enhances the efficacy of paclitaxel in ovarian cancer by reversing drug resistance and tumor stem-like properties. Cancer Research. PMID 29891506 DOI: 10.1158/0008-5472.CAN-17-3993  0.01
2018 Hyter S, Hirst J, Pathak H, Pessetto ZY, Koestler DC, Raghavan R, Pei D, Godwin AK. Developing a genetic signature to predict drug response in ovarian cancer. Oncotarget. 9: 14828-14848. PMID 29599910 DOI: 10.18632/oncotarget.23663  0.01
2018 Sharma P, Abramson VG, O'Dea A, Pathak HB, Pessetto ZY, Wang YY, Finke K, Hoffmann MS, Elia M, Lewis S, Scott J, De Jong J, Urban J, Heldstab J, LaFaver S, et al. Clinical and biomarker results from phase I/II study of PI3K inhibitor BYL 719 (alpelisib) plus nab-paclitaxel in HER2-negative metastatic breast cancer. Journal of Clinical Oncology. 36: 1018-1018. DOI: 10.1200/JCO.2018.36.15_SUPPL.1018  0.01
2017 Sharma P, Barlow WE, Godwin AK, Pathak H, Isakova K, Williams D, Timms KM, Hartman AR, Wenstrup RJ, Linden HM, Tripathy D, Hortobagyi GN, Hayes DF. Impact of homologous recombination deficiency biomarkers on outcomes in patients with triple-negative breast cancer treated with doxorubicin-based adjuvant chemotherapy (SWOG S9313). Annals of Oncology : Official Journal of the European Society For Medical Oncology. PMID 29293876 DOI: 10.1093/annonc/mdx821  0.01
2016 Raghavan R, Hyter S, Pathak HB, Godwin AK, Konecny G, Wang C, Goode EL, Fridley BL. Drug discovery using clinical outcome-based Connectivity Mapping: application to ovarian cancer. Bmc Genomics. 17: 811. PMID 27756228 DOI: 10.1186/S12864-016-3149-5  0.01
2016 Zook P, Pathak HB, Belinsky M, Gersz L, Devarajan K, Zhou Y, Godwin AK, von Mehren M, Rink LA. Combination of Imatinib Mesylate and AKT Inhibitor Provides Synergistic Effects in Preclinical Study of Gastrointestinal Stromal Tumor. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27370604 DOI: 10.1158/1078-0432.Ccr-16-0529  0.01
2012 Ramus SJ, Antoniou AC, Kuchenbaecker KB, Soucy P, Beesley J, Chen X, McGuffog L, Sinilnikova OM, Healey S, Barrowdale D, Lee A, Thomassen M, Gerdes AM, Kruse TA, Jensen UB, ... Pathak H, et al. Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers. Human Mutation. 33: 690-702. PMID 22253144 DOI: 10.1002/Humu.22025  0.01
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