Rachel A. Mooney, Ph.D. - Publications

Affiliations: 
2007 University of Wisconsin, Madison, Madison, WI 
Area:
Molecular Biology, Microbiology Biology

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Shiver AL, Osadnik H, Peters JM, Mooney RA, Wu PI, Henry KK, Braberg H, Krogan NJ, Hu JC, Landick R, Huang KC, Gross CA. Chemical-genetic interrogation of RNA polymerase mutants reveals structure-function relationships and physiological tradeoffs. Molecular Cell. 81: 2201-2215.e9. PMID 34019789 DOI: 10.1016/j.molcel.2021.04.027  0.732
2020 Lilic M, Chen J, Boyaci H, Braffman N, Hubin EA, Herrmann J, Müller R, Mooney R, Landick R, Darst SA, Campbell EA. The antibiotic sorangicin A inhibits promoter DNA unwinding in a rifampicin-resistant RNA polymerase. Proceedings of the National Academy of Sciences of the United States of America. PMID 33199626 DOI: 10.1073/pnas.2013706117  0.625
2019 Stumper SK, Ravi H, Friedman LJ, Mooney RA, Corrêa IR, Gershenson A, Landick R, Gelles J. Delayed inhibition mechanism for secondary channel factor regulation of ribosomal RNA transcription. Elife. 8. PMID 30720429 DOI: 10.7554/Elife.40576  0.729
2019 Bellecourt MJ, Ray-Soni A, Harwig A, Mooney RA, Landick R. RNA Polymerase Clamp Movement Aids Dissociation from DNA but Is Not Required for RNA Release at Intrinsic Terminators. Journal of Molecular Biology. PMID 30630008 DOI: 10.1016/J.Jmb.2019.01.003  0.721
2019 Saba J, Chua XY, Mishanina TV, Nayak D, Windgassen TA, Mooney RA, Landick R. The elemental mechanism of transcriptional pausing. Elife. 8. PMID 30618376 DOI: 10.7554/Elife.40981  0.718
2019 Stumper SK, Ravi H, Friedman LJ, Mooney RA, Jnr IRC, Gershenson A, Landick R, Gelles J. Author response: Delayed inhibition mechanism for secondary channel factor regulation of ribosomal RNA transcription Elife. DOI: 10.7554/Elife.40576.Sa2  0.7
2018 Kang JY, Mooney RA, Nedialkov Y, Saba J, Mishanina TV, Artsimovitch I, Landick R, Darst SA. Structural Basis for Transcript Elongation Control by NusG Family Universal Regulators. Cell. PMID 29887376 DOI: 10.1016/J.Cell.2018.05.017  0.719
2018 Helmling C, Klötzner DP, Sochor F, Mooney RA, Wacker A, Landick R, Fürtig B, Heckel A, Schwalbe H. Life times of metastable states guide regulatory signaling in transcriptional riboswitches. Nature Communications. 9: 944. PMID 29507289 DOI: 10.1038/S41467-018-03375-W  0.716
2018 Kang JY, Mishanina TV, Bellecourt MJ, Mooney RA, Darst SA, Landick R. RNA Polymerase Accommodates a Pause RNA Hairpin by Global Conformational Rearrangements that Prolong Pausing. Molecular Cell. 69: 802-815.e1. PMID 29499135 DOI: 10.1016/J.Molcel.2018.01.018  0.751
2018 Boyaci H, Chen J, Lilic M, Palka M, Mooney RA, Landick R, Darst SA, Campbell EA. Fidaxomicin jamsRNA polymerase motions needed for initiation via RbpA contacts. Elife. 7. PMID 29480804 DOI: 10.7554/eLife.34823  0.641
2018 Saba J, Chua XY, Mishanina TV, Nayak D, Windgassen TA, Mooney RA, Landick R. Author response: The elemental mechanism of transcriptional pausing Elife. DOI: 10.7554/Elife.40981.025  0.575
2018 Boyaci H, Chen J, Lilic M, Palka M, Mooney RA, Landick R, Darst SA, Campbell EA. Author response: Fidaxomicin jams Mycobacterium tuberculosis RNA polymerase motions needed for initiation via RbpA contacts Elife. DOI: 10.7554/Elife.34823.030  0.631
2018 Kang JY, Mooney RA, Artsimovitch I, Landick R, Darst SA. Molecular mechanism of transcription pause inhibition by elongation factor NusG and RfaH Cell. DOI: 10.2210/Pdb6C6T/Pdb  0.609
2018 Boyaci H, Chen J, Lilic M, Palka M, Mooney RA, Landick R, Darst SA, Campbell EA. Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts. Elife. 7. DOI: 10.2210/Pdb6C04/Pdb  0.645
2017 Ray-Soni A, Mooney RA, Landick R. Trigger loop dynamics can explain stimulation of intrinsic termination by bacterial RNA polymerase without terminator hairpin contact. Proceedings of the National Academy of Sciences of the United States of America. PMID 29078293 DOI: 10.1073/Pnas.1706247114  0.714
2017 Mishanina TV, Palo MZ, Nayak D, Mooney RA, Landick R. Trigger loop of RNA polymerase is a positional, not acid-base, catalyst for both transcription and proofreading. Proceedings of the National Academy of Sciences of the United States of America. PMID 28607053 DOI: 10.1073/Pnas.1702383114  0.722
2017 Steinert H, Sochor F, Wacker A, Buck J, Helmling C, Hiller F, Keyhani S, Noeske J, Grimm SK, Rudolph MM, Keller H, Mooney RA, Landick R, Suess B, Fürtig B, et al. Pausing guides RNA folding to populate transiently stable RNA structures for riboswitch-based transcription regulation. Elife. 6. PMID 28541183 DOI: 10.7554/Elife.21297  0.716
2017 Kohler R, Mooney RA, Mills DJ, Landick R, Cramer P. Architecture of a transcribing-translating expressome. Science (New York, N.Y.). 356: 194-197. PMID 28408604 DOI: 10.1126/Science.Aal3059  0.733
2017 Tetone LE, Friedman LJ, Osborne ML, Ravi H, Kyzer S, Stumper SK, Mooney RA, Landick R, Gelles J. Dynamics of GreB-RNA polymerase interaction allow a proofreading accessory protein to patrol for transcription complexes needing rescue. Proceedings of the National Academy of Sciences of the United States of America. PMID 28137878 DOI: 10.1073/Pnas.1616525114  0.691
2017 Steinert H, Sochor F, Wacker A, Buck J, Helmling C, Hiller F, Keyhani S, Noeske J, Grimm S, Rudolph MM, Keller H, Mooney RA, Landick R, Suess B, Fürtig B, et al. Author response: Pausing guides RNA folding to populate transiently stable RNA structures for riboswitch-based transcription regulation Elife. DOI: 10.7554/Elife.21297.018  0.727
2015 Tetone LE, Friedman LJ, Osborne ML, Ravi H, Kyzer S, Mooney RA, Landick R, Gelles J. Dynamics of GreB Interactions with RNA Polymerase: How a Regulatory Protein may Patrol the Genome for Transcription Complexes to Rescue Biophysical Journal. 108: 507a-508a. DOI: 10.1016/J.Bpj.2014.11.2778  0.71
2014 Windgassen TA, Mooney RA, Nayak D, Palangat M, Zhang J, Landick R. Trigger-helix folding pathway and SI3 mediate catalysis and hairpin-stabilized pausing by Escherichia coli RNA polymerase. Nucleic Acids Research. 42: 12707-21. PMID 25336618 DOI: 10.1093/Nar/Gku997  0.745
2014 Hein PP, Kolb KE, Windgassen T, Bellecourt MJ, Darst SA, Mooney RA, Landick R. RNA polymerase pausing and nascent-RNA structure formation are linked through clamp-domain movement. Nature Structural & Molecular Biology. 21: 794-802. PMID 25108353 DOI: 10.1038/Nsmb.2867  0.815
2014 Larson MH, Mooney RA, Peters JM, Windgassen T, Nayak D, Gross CA, Block SM, Greenleaf WJ, Landick R, Weissman JS. A pause sequence enriched at translation start sites drives transcription dynamics in vivo. Science (New York, N.Y.). 344: 1042-7. PMID 24789973 DOI: 10.1126/Science.1251871  0.75
2014 Czyz A, Mooney RA, Iaconi A, Landick R. Mycobacterial RNA polymerase requires a U-tract at intrinsic terminators and is aided by NusG at suboptimal terminators. Mbio. 5: e00931. PMID 24713321 DOI: 10.1128/Mbio.00931-14  0.737
2014 Zhang Y, Mooney RA, Grass JA, Sivaramakrishnan P, Herman C, Landick R, Wang JD. DksA guards elongating RNA polymerase against ribosome-stalling-induced arrest. Molecular Cell. 53: 766-78. PMID 24606919 DOI: 10.1016/J.Molcel.2014.02.005  0.758
2013 Mooney RA, Landick R. Building a better stop sign: understanding the signals that terminate transcription. Nature Methods. 10: 618-9. PMID 23807194 DOI: 10.1038/Nmeth.2527  0.613
2013 Nayak D, Voss M, Windgassen T, Mooney RA, Landick R. Cys-pair reporters detect a constrained trigger loop in a paused RNA polymerase. Molecular Cell. 50: 882-93. PMID 23769674 DOI: 10.1016/J.Molcel.2013.05.015  0.74
2012 Peters JM, Mooney RA, Grass JA, Jessen ED, Tran F, Landick R. Rho and NusG suppress pervasive antisense transcription in Escherichia coli. Genes & Development. 26: 2621-33. PMID 23207917 DOI: 10.1101/Gad.196741.112  0.76
2012 Koslover DJ, Fazal FM, Mooney RA, Landick R, Block SM. Binding and translocation of termination factor rho studied at the single-molecule level. Journal of Molecular Biology. 423: 664-76. PMID 22885804 DOI: 10.1016/J.Jmb.2012.07.027  0.697
2012 Burmann BM, Knauer SH, Sevostyanova A, Schweimer K, Mooney RA, Landick R, Artsimovitch I, Rösch P. An α helix to β barrel domain switch transforms the transcription factor RfaH into a translation factor. Cell. 150: 291-303. PMID 22817892 DOI: 10.1016/J.Cell.2012.05.042  0.668
2011 Bratton BP, Mooney RA, Weisshaar JC. Spatial distribution and diffusive motion of RNA polymerase in live Escherichia coli. Journal of Bacteriology. 193: 5138-46. PMID 21784927 DOI: 10.1128/Jb.00198-11  0.362
2011 Sevostyanova A, Belogurov GA, Mooney RA, Landick R, Artsimovitch I. The β subunit gate loop is required for RNA polymerase modification by RfaH and NusG. Molecular Cell. 43: 253-62. PMID 21777814 DOI: 10.1016/J.Molcel.2011.05.026  0.731
2011 Davis SE, Mooney RA, Kanin EI, Grass J, Landick R, Ansari AZ. Mapping E. coli RNA polymerase and associated transcription factors and identifying promoters genome-wide. Methods in Enzymology. 498: 449-71. PMID 21601690 DOI: 10.1016/B978-0-12-385120-8.00020-6  0.662
2010 Cohen SE, Lewis CA, Mooney RA, Kohanski MA, Collins JJ, Landick R, Walker GC. Roles for the transcription elongation factor NusA in both DNA repair and damage tolerance pathways in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 107: 15517-22. PMID 20696893 DOI: 10.1073/Pnas.1005203107  0.628
2010 Herbert KM, Zhou J, Mooney RA, Porta AL, Landick R, Block SM. E. coli NusG inhibits backtracking and accelerates pause-free transcription by promoting forward translocation of RNA polymerase. Journal of Molecular Biology. 399: 17-30. PMID 20381500 DOI: 10.1016/J.Jmb.2010.03.051  0.704
2009 Peters JM, Mooney RA, Kuan PF, Rowland JL, Keles S, Landick R. Rho directs widespread termination of intragenic and stable RNA transcription. Proceedings of the National Academy of Sciences of the United States of America. 106: 15406-11. PMID 19706412 DOI: 10.1073/Pnas.0903846106  0.802
2009 Mooney RA, Schweimer K, Rösch P, Gottesman M, Landick R. Two structurally independent domains of E. coli NusG create regulatory plasticity via distinct interactions with RNA polymerase and regulators. Journal of Molecular Biology. 391: 341-58. PMID 19500594 DOI: 10.1016/J.Jmb.2009.05.078  0.726
2009 Mooney RA, Davis SE, Peters JM, Rowland JL, Ansari AZ, Landick R. Regulator trafficking on bacterial transcription units in vivo. Molecular Cell. 33: 97-108. PMID 19150431 DOI: 10.1016/J.Molcel.2008.12.021  0.753
2009 Belogurov GA, Mooney RA, Svetlov V, Landick R, Artsimovitch I. Functional specialization of transcription elongation factors. The Embo Journal. 28: 112-22. PMID 19096362 DOI: 10.1038/Emboj.2008.268  0.708
2008 Westblade LF, Minakhin L, Kuznedelov K, Tackett AJ, Chang EJ, Mooney RA, Vvedenskaya I, Wang QJ, Fenyö D, Rout MP, Landick R, Chait BT, Severinov K, Darst SA. Rapid isolation and identification of bacteriophage T4-encoded modifications of Escherichia coli RNA polymerase: a generic method to study bacteriophage/host interactions. Journal of Proteome Research. 7: 1244-50. PMID 18271525 DOI: 10.1021/Pr070451J  0.676
2006 Herbert KM, La Porta A, Wong BJ, Mooney RA, Neuman KC, Landick R, Block SM. Sequence-resolved detection of pausing by single RNA polymerase molecules. Cell. 125: 1083-94. PMID 16777599 DOI: 10.1016/J.Cell.2006.04.032  0.665
2006 Ederth J, Mooney RA, Isaksson LA, Landick R. Functional interplay between the jaw domain of bacterial RNA polymerase and allele-specific residues in the product RNA-binding pocket. Journal of Molecular Biology. 356: 1163-79. PMID 16405998 DOI: 10.1016/J.Jmb.2005.11.080  0.746
2005 Mooney RA, Darst SA, Landick R. Sigma and RNA polymerase: an on-again, off-again relationship? Molecular Cell. 20: 335-45. PMID 16285916 DOI: 10.1016/J.Molcel.2005.10.015  0.745
2004 Geszvain K, Gruber TM, Mooney RA, Gross CA, Landick R. A hydrophobic patch on the flap-tip helix of E.coli RNA polymerase mediates sigma(70) region 4 function. Journal of Molecular Biology. 343: 569-87. PMID 15465046 DOI: 10.1016/J.Jmb.2004.08.063  0.786
2003 Mooney RA, Landick R. Tethering sigma70 to RNA polymerase reveals high in vivo activity of sigma factors and sigma70-dependent pausing at promoter-distal locations. Genes & Development. 17: 2839-51. PMID 14630944 DOI: 10.1101/Gad.1142203  0.716
2003 Santangelo TJ, Mooney RA, Landick R, Roberts JW. RNA polymerase mutations that impair conversion to a termination-resistant complex by Q antiterminator proteins. Genes & Development. 17: 1281-92. PMID 12756229 DOI: 10.1101/Gad.1082103  0.707
2002 Yuzenkova J, Delgado M, Nechaev S, Savalia D, Epshtein V, Artsimovitch I, Mooney RA, Landick R, Farias RN, Salomon R, Severinov K. Mutations of bacterial RNA polymerase leading to resistance to microcin j25. The Journal of Biological Chemistry. 277: 50867-75. PMID 12401787 DOI: 10.1074/Jbc.M209425200  0.597
2000 Opalka N, Mooney RA, Richter C, Severinov K, Landick R, Darst SA. Direct localization of a beta-subunit domain on the three-dimensional structure of Escherichia coli RNA polymerase. Proceedings of the National Academy of Sciences of the United States of America. 97: 617-22. PMID 10639128 DOI: 10.1073/Pnas.97.2.617  0.628
1999 Mooney RA, Landick R. RNA polymerase unveiled. Cell. 98: 687-90. PMID 10499791 DOI: 10.1016/S0092-8674(00)81483-X  0.685
1998 Mooney RA, Artsimovitch I, Landick R. Information processing by RNA polymerase: recognition of regulatory signals during RNA chain elongation. Journal of Bacteriology. 180: 3265-75. PMID 9642176 DOI: 10.1128/Jb.180.13.3265-3275.1998  0.712
1997 Severinov K, Mooney R, Darst SA, Landick R. Tethering of the large subunits of Escherichia coli RNA polymerase. The Journal of Biological Chemistry. 272: 24137-40. PMID 9305860 DOI: 10.1074/Jbc.272.39.24137  0.667
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