Lynne-Marie Postovit, Ph.D. - Publications

2004 Queen's University, Canada, Kingston, Ontario, Canada 
Cell Biology

68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Siegers GM, Dutta I, Kang EY, Huang J, Köbel M, Postovit LM. Aberrantly Expressed Embryonic Protein NODAL Alters Breast Cancer Cell Susceptibility to γδ T Cell Cytotoxicity. Frontiers in Immunology. 11: 1287. PMID 32636849 DOI: 10.3389/fimmu.2020.01287  0.44
2020 Jewer M, Lee L, Leibovitch M, Zhang G, Liu J, Findlay SD, Vincent KM, Tandoc K, Dieters-Castator D, Quail DF, Dutta I, Coatham M, Xu Z, Puri A, Guan BJ, ... ... Postovit LM, et al. Translational control of breast cancer plasticity. Nature Communications. 11: 2498. PMID 32427827 DOI: 10.1038/s41467-020-16352-z  0.6
2019 Chatterjee S, Bhat V, Berdnikov A, Liu J, Zhang G, Buchel E, Safneck J, Marshall AJ, Murphy LC, Postovit LM, Raouf A. Paracrine Crosstalk between Fibroblasts and ER Breast Cancer Cells Creates an IL1β-Enriched Niche that Promotes Tumor Growth. Iscience. 19: 388-401. PMID 31419632 DOI: 10.1016/j.isci.2019.07.034  0.4
2019 Postovit LM, Dieters-Castator DZ, Rambau PF, Kelemen LE, Siegers GM, Lajoie GA, Köbel M. Proteomics derived biomarker panel improves diagnostic precision to classify endometrioid and high-grade serous ovarian carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30979743 DOI: 10.1158/1078-0432.CCR-18-3818  0.44
2019 Guo Q, Li VZ, Nichol JN, Huang F, Yang W, Preston SEJ, Talat Z, Lefrère H, Yu H, Zhang G, Basik M, Gonçalves C, Zhan Y, Plourde D, Su J, ... ... Postovit LM, et al. MNK1/NODAL signaling promotes invasive progression of breast ductal carcinoma in situ. Cancer Research. PMID 30659022 DOI: 10.1158/0008-5472.CAN-18-1602  0.4
2018 Siegers GM, Dutta I, Lai R, Postovit LM. Functional Plasticity of Gamma Delta T Cells and Breast Tumor Targets in Hypoxia. Frontiers in Immunology. 9: 1367. PMID 29963058 DOI: 10.3389/fimmu.2018.01367  0.44
2017 Bilyk O, Coatham M, Jewer M, Postovit LM. Epithelial-to-Mesenchymal Transition in the Female Reproductive Tract: From Normal Functioning to Disease Pathology. Frontiers in Oncology. 7: 145. PMID 28725636 DOI: 10.3389/fonc.2017.00145  0.44
2017 Dutta I, Postovit LM, Siegers GM. Apoptosis Induced via Gamma Delta T Cell Antigen Receptor "Blocking" Antibodies: A Cautionary Tale. Frontiers in Immunology. 8: 776. PMID 28713391 DOI: 10.3389/fimmu.2017.00776  0.44
2016 Siegers GM, Barreira CR, Postovit LM, Dekaban GA. CD11d β2 integrin expression on human NK, B, and γδ T cells. Journal of Leukocyte Biology. PMID 27881604 DOI: 10.1189/jlb.3AB0716-326RR  0.44
2016 Majumder M, Xin X, Liu L, Tutunea-Fatan E, Rodriguez-Torres M, Vincent K, Postovit LM, Hess D, Lala PK. COX-2 Induces Breast Cancer Stem Cells via EP4/PI3K/AKT/NOTCH/WNT Axis. Stem Cells (Dayton, Ohio). PMID 27301070 DOI: 10.1002/stem.2426  0.72
2016 Volodko N, Salla M, Zare A, Abulghasem el-A, Vincent K, Benesch MG, McMullen TP, Bathe OF, Postovit L, Baksh S. RASSF1A Site-Specific Methylation Hotspots in Cancer and Correlation with RASSF1C and MOAP-1. Cancers. 8. PMID 27294960 DOI: 10.3390/cancers8060055  0.72
2016 Findlay SD, Vincent KM, Berman JR, Postovit LM. A Digital PCR-Based Method for Efficient and Highly Specific Screening of Genome Edited Cells. Plos One. 11: e0153901. PMID 27089539 DOI: 10.1371/journal.pone.0153901  0.72
2016 El-Sehemy A, Postovit LM, Fu Y. Nitric oxide signaling in human ovarian cancer: a potential therapeutic target. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. PMID 26891890 DOI: 10.1016/j.niox.2016.02.002  0.72
2015 Findlay SD, Postovit LM. Brief Report: Common Genetic Variation in Chromosome 10 q22.1 Shows a Strong Sex Bias in Human Embryonic Stem Cell Lines and Directly Controls the Novel Alternative Splicing of Human NODAL which is Associated with XIST Expression in Female Cell Lines. Stem Cells (Dayton, Ohio). PMID 26662182 DOI: 10.1002/stem.2258  0.72
2015 Barghout SH, Zepeda N, Vincent K, Azad AK, Xu Z, Yang C, Steed H, Postovit LM, Fu Y. RUNX3 contributes to carboplatin resistance in epithelial ovarian cancer cells. Gynecologic Oncology. 138: 647-55. PMID 26186909 DOI: 10.1016/j.ygyno.2015.07.009  0.72
2015 Hoang LN, McConechy MK, Köbel M, Anglesio M, Senz J, Maassen M, Kommoss S, Meng B, Postovit L, Kelemen LE, Staebler A, Brucker S, Krämer B, McAlpine JN, Gilks CB, et al. Polymerase Epsilon Exonuclease Domain Mutations in Ovarian Endometrioid Carcinoma. International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. 25: 1187-93. PMID 26166557 DOI: 10.1097/IGC.0000000000000492  0.72
2015 Vincent KM, Findlay SD, Postovit LM. Assessing breast cancer cell lines as tumour models by comparison of mRNA expression profiles Breast Cancer Research. 17. DOI: 10.1186/s13058-015-0613-0  0.72
2015 Hutchenreuther J, Vincent KM, Carter DE, Postovit LM, Leask A. CCN2 Expression by Tumor Stroma Is Required for Melanoma Metastasis Journal of Investigative Dermatology. DOI: 10.1038/jid.2015.279  0.72
2015 Postovit LM. Role of nitric oxide in the regulation of the pro-tumourigenic hypoxic phenotype: From instigation to mitigation Nitric Oxide and Cancer: Pathogenesis and Therapy. 65-84. DOI: 10.1007/978-3-319-13611-0_5  0.72
2014 Law J, Zhang G, Dragan M, Postovit LM, Bhattacharya M. Nodal signals via β-arrestins and RalGTPases to regulate trophoblast invasion. Cellular Signalling. 26: 1935-42. PMID 24863882 DOI: 10.1016/j.cellsig.2014.05.009  0.72
2014 Radan L, Hughes CS, Teichroeb JH, Vieira Zamora FM, Jewer M, Postovit LM, Betts DH. Microenvironmental regulation of telomerase isoforms in human embryonic stem cells. Stem Cells and Development. 23: 2046-66. PMID 24749509 DOI: 10.1089/scd.2013.0373  0.72
2014 Quail DF, Zhang G, Findlay SD, Hess DA, Postovit LM. Nodal promotes invasive phenotypes via a mitogen-activated protein kinase-dependent pathway. Oncogene. 33: 461-73. PMID 23334323 DOI: 10.1038/onc.2012.608  0.72
2013 Das P, Siegers GM, Postovit LM. Illuminating luminal B: QSOX1 as a subtype-specific biomarker. Breast Cancer Research : Bcr. 15: 104. PMID 23680167 DOI: 10.1186/bcr3417  0.72
2013 Quail DF, Siegers GM, Jewer M, Postovit LM. Nodal signalling in embryogenesis and tumourigenesis. The International Journal of Biochemistry & Cell Biology. 45: 885-98. PMID 23291354 DOI: 10.1016/j.biocel.2012.12.021  0.72
2012 Quail DF, Zhang G, Walsh LA, Siegers GM, Dieters-Castator DZ, Findlay SD, Broughton H, Putman DM, Hess DA, Postovit LM. Embryonic morphogen nodal promotes breast cancer growth and progression. Plos One. 7: e48237. PMID 23144858 DOI: 10.1371/journal.pone.0048237  0.72
2012 Jewer M, Findlay SD, Postovit LM. Post-transcriptional regulation in cancer progression : Microenvironmental control of alternative splicing and translation. Journal of Cell Communication and Signaling. 6: 233-48. PMID 23054595 DOI: 10.1007/s12079-012-0179-x  0.72
2012 Hughes C, Radan L, Chang WY, Stanford WL, Betts DH, Postovit LM, Lajoie GA. Mass spectrometry-based proteomic analysis of the matrix microenvironment in pluripotent stem cell culture. Molecular & Cellular Proteomics : McP. 11: 1924-36. PMID 23023296 DOI: 10.1074/mcp.M112.020057  0.72
2012 Quail DF, Walsh LA, Zhang G, Findlay SD, Moreno J, Fung L, Ablack A, Lewis JD, Done SJ, Hess DA, Postovit LM. Embryonic protein nodal promotes breast cancer vascularization. Cancer Research. 72: 3851-63. PMID 22855743 DOI: 10.1158/0008-5472.CAN-11-3951  0.72
2012 Quail DF, MacIel TJ, Rogers K, Postovit LM. A unique 3D in vitro cellular invasion assay Journal of Biomolecular Screening. 17: 1088-1095. PMID 22706347 DOI: 10.1177/1087057112449863  0.72
2012 Quail DF, Taylor MJ, Postovit LM. Microenvironmental regulation of cancer stem cell phenotypes. Current Stem Cell Research & Therapy. 7: 197-216. PMID 22329582 DOI: 10.2174/157488812799859838  0.72
2012 Medeiros PJ, Al-Khazraji BK, Novielli NM, Postovit LM, Chambers AF, Jackson DN. Neuropeptide Y stimulates proliferation and migration in the 4T1 breast cancer cell line. International Journal of Cancer. Journal International Du Cancer. 131: 276-86. PMID 21823118 DOI: 10.1002/ijc.26350  0.72
2011 Quail DF, Taylor MJ, Walsh LA, Dieters-Castator D, Das P, Jewer M, Zhang G, Postovit LM. Low oxygen levels induce the expression of the embryonic morphogen Nodal. Molecular Biology of the Cell. 22: 4809-21. PMID 22031289 DOI: 10.1091/mbc.E11-03-0263  0.72
2011 Hughes CS, Radan L, Betts D, Postovit LM, Lajoie GA. Proteomic analysis of extracellular matrices used in stem cell culture. Proteomics. 11: 3983-91. PMID 21834137 DOI: 10.1002/pmic.201100030  0.72
2011 Zajac M, Law J, Cvetkovic DD, Pampillo M, McColl L, Pape C, Di Guglielmo GM, Postovit LM, Babwah AV, Bhattacharya M. GPR54 (KISS1R) transactivates EGFR to promote breast cancer cell invasiveness. Plos One. 6: e21599. PMID 21738726 DOI: 10.1371/journal.pone.0021599  0.72
2011 Lawrence MG, Margaryan NV, Loessner D, Collins A, Kerr KM, Turner M, Seftor EA, Stephens CR, Lai J, Postovit LM, Clements JA, Hendrix MJ. Reactivation of embryonic nodal signaling is associated with tumor progression and promotes the growth of prostate cancer cells. The Prostate. 71: 1198-209. PMID 21656830 DOI: 10.1002/pros.21335  0.72
2011 Hughes CS, Nuhn AA, Postovit LM, Lajoie GA. Proteomics of human embryonic stem cells. Proteomics. 11: 675-90. PMID 21225999 DOI: 10.1002/pmic.201000407  0.72
2010 Hardy KM, Kirschmann DA, Seftor EA, Margaryan NV, Postovit LM, Strizzi L, Hendrix MJ. Regulation of the embryonic morphogen Nodal by Notch4 facilitates manifestation of the aggressive melanoma phenotype. Cancer Research. 70: 10340-50. PMID 21159651 DOI: 10.1158/0008-5472.CAN-10-0705  0.72
2010 Hughes CS, Postovit LM, Lajoie GA. Matrigel: a complex protein mixture required for optimal growth of cell culture. Proteomics. 10: 1886-90. PMID 20162561 DOI: 10.1002/pmic.200900758  0.72
2009 Zhang J, Postovit LM, Wang D, Gardiner RB, Harris R, Abdul M, Thomas A. In situ loading of basic fibroblast growth factor within porous silica nanoparticles for a prolonged release. Nanoscale Research Letters. 4: 1297-302. PMID 20628467 DOI: 10.1007/s11671-009-9395-6  0.72
2009 Strizzi L, Postovit LM, Margaryan NV, Lipavsky A, Gadiot J, Blank C, Seftor RE, Seftor EA, Hendrix MJ. Nodal as a biomarker for melanoma progression and a new therapeutic target for clinical intervention. Expert Review of Dermatology. 4: 67-78. PMID 19885369 DOI: 10.1586/17469872.4.1.67  0.72
2009 Strizzi L, Hardy KM, Seftor EA, Costa FF, Kirschmann DA, Seftor RE, Postovit LM, Hendrix MJ. Development and cancer: at the crossroads of Nodal and Notch signaling. Cancer Research. 69: 7131-4. PMID 19738053 DOI: 10.1158/0008-5472.CAN-09-1199  0.72
2009 Li TT, Alemayehu M, Aziziyeh AI, Pape C, Pampillo M, Postovit LM, Mills GB, Babwah AV, Bhattacharya M. Beta-arrestin/Ral signaling regulates lysophosphatidic acid-mediated migration and invasion of human breast tumor cells. Molecular Cancer Research : McR. 7: 1064-77. PMID 19609003 DOI: 10.1158/1541-7786.MCR-08-0578  0.72
2009 Galat V, Binas B, Iannaccone S, Postovit LM, Debeb BG, Iannaccone P. Developmental potential of rat extraembryonic stem cells. Stem Cells and Development. 18: 1309-18. PMID 19480599 DOI: 10.1089/scd.2009.0115  0.72
2009 Strizzi L, Hardy KM, Seftor EA, Costa FF, Kirschmann DA, Seftor REB, Postovit LM, Hendrix MJC. Development and cancer: At the crossroads of Nodal and Notch signaling (Cancer Research (2009) 69, (7131-7134)) Cancer Research. 69: 8526-8527. DOI: 10.1158/0008-5472.CAN-09-3534  0.72
2008 Abbott DE, Bailey CM, Postovit LM, Seftor EA, Margaryan N, Seftor RE, Hendrix MJ. The epigenetic influence of tumor and embryonic microenvironments: how different are they? Cancer Microenvironment : Official Journal of the International Cancer Microenvironment Society. 1: 13-21. PMID 19308681 DOI: 10.1007/s12307-008-0004-5  0.72
2008 Strizzi L, Postovit LM, Margaryan NV, Seftor EA, Abbott DE, Seftor RE, Salomon DS, Hendrix MJ. Emerging roles of nodal and Cripto-1: from embryogenesis to breast cancer progression. Breast Disease. 29: 91-103. PMID 19029628  0.72
2008 Kasemeier-Kulesa JC, Teddy JM, Postovit LM, Seftor EA, Seftor RE, Hendrix MJ, Kulesa PM. Reprogramming multipotent tumor cells with the embryonic neural crest microenvironment. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 2657-66. PMID 18629870 DOI: 10.1002/dvdy.21613  0.72
2008 Postovit LM, Margaryan NV, Seftor EA, Hendrix MJ. Role of nodal signaling and the microenvironment underlying melanoma plasticity. Pigment Cell & Melanoma Research. 21: 348-57. PMID 18444961 DOI: 10.1111/j.1755-148X.2008.00463.x  0.72
2008 Postovit LM, Margaryan NV, Seftor EA, Kirschmann DA, Lipavsky A, Wheaton WW, Abbott DE, Seftor RE, Hendrix MJ. Human embryonic stem cell microenvironment suppresses the tumorigenic phenotype of aggressive cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 4329-34. PMID 18334633 DOI: 10.1073/pnas.0800467105  0.72
2008 Postovit LM, Abbott DE, Payne SL, Wheaton WW, Margaryan NV, Sullivan R, Jansen MK, Csiszar K, Hendrix MJ, Kirschmann DA. Hypoxia/reoxygenation: a dynamic regulator of lysyl oxidase-facilitated breast cancer migration. Journal of Cellular Biochemistry. 103: 1369-78. PMID 17685448 DOI: 10.1002/jcb.21517  0.72
2007 Abbott DE, Postovit LM, Seftor EA, Margaryan NV, Seftor RE, Hendrix MJ. Exploiting the convergence of embryonic and tumorigenic signaling pathways to develop new therapeutic targets. Stem Cell Reviews. 3: 68-78. PMID 17873384 DOI: 10.1007/s12015-007-0010-x  0.72
2007 Hendrix MJ, Seftor EA, Seftor RE, Kasemeier-Kulesa J, Kulesa PM, Postovit LM. Reprogramming metastatic tumour cells with embryonic microenvironments. Nature Reviews. Cancer. 7: 246-55. PMID 17384580 DOI: 10.1038/nrc2108  0.72
2007 Postovit LM, Seftor EA, Seftor RE, Hendrix MJ. Targeting Nodal in malignant melanoma cells. Expert Opinion On Therapeutic Targets. 11: 497-505. PMID 17373879 DOI: 10.1517/14728222.11.4.497  0.72
2007 Postovit LM, Costa FF, Bischof JM, Seftor EA, Wen B, Seftor RE, Feinberg AP, Soares MB, Hendrix MJ. The commonality of plasticity underlying multipotent tumor cells and embryonic stem cells. Journal of Cellular Biochemistry. 101: 908-17. PMID 17177292 DOI: 10.1002/jcb.21227  0.72
2006 Postovit LM, Seftor EA, Seftor RE, Hendrix MJ. Influence of the microenvironment on melanoma cell fate determination and phenotype. Cancer Research. 66: 7833-6. PMID 16912153 DOI: 10.1158/0008-5472.CAN-06-0731  0.72
2006 Topczewska JM, Postovit LM, Margaryan NV, Sam A, Hess AR, Wheaton WW, Nickoloff BJ, Topczewski J, Hendrix MJ. Embryonic and tumorigenic pathways converge via Nodal signaling: role in melanoma aggressiveness. Nature Medicine. 12: 925-32. PMID 16892036 DOI: 10.1038/nm1448  0.72
2006 Postovit LM, Seftor EA, Seftor RE, Hendrix MJ. A three-dimensional model to study the epigenetic effects induced by the microenvironment of human embryonic stem cells. Stem Cells (Dayton, Ohio). 24: 501-5. PMID 16293574 DOI: 10.1634/stemcells.2005-0459  0.72
2006 Topczewska JM, Postovit LM, Margaryan NV, Sam A, Hess AR, Wheaton WW, Nickoloff BJ, Topczewski J, Hendrix MJC. Reply to Melanoma pathogenesis and Nodal: A partial picture? [2] Nature Medicine. 12: 1231. DOI: 10.1038/nm1106-1231b  0.72
2005 Hess AR, Postovit LM, Margaryan NV, Seftor EA, Schneider GB, Seftor RE, Nickoloff BJ, Hendrix MJ. Focal adhesion kinase promotes the aggressive melanoma phenotype. Cancer Research. 65: 9851-60. PMID 16267008 DOI: 10.1158/0008-5472.CAN-05-2172  0.72
2005 Renaud SJ, Postovit LM, Macdonald-Goodfellow SK, McDonald GT, Caldwell JD, Graham CH. Activated macrophages inhibit human cytotrophoblast invasiveness in vitro. Biology of Reproduction. 73: 237-43. PMID 15800179 DOI: 10.1095/biolreprod.104.038000  0.72
2005 Postovit LM, Sullivan R, Adams MA, Graham CH. Nitric oxide signalling and cellular adaptations to changes in oxygenation. Toxicology. 208: 235-48. PMID 15691588 DOI: 10.1016/j.tox.2004.11.022  0.72
2004 Postovit LM, Adams MA, Lash GE, Heaton JP, Graham CH. Nitric oxide-mediated regulation of hypoxia-induced B16F10 melanoma metastasis. International Journal of Cancer. Journal International Du Cancer. 108: 47-53. PMID 14618614 DOI: 10.1002/ijc.11556  0.72
2002 Postovit LM, Dutt P, Dourdin N, Park M, Greer PA, Graham CH, Elce JS. Calpain is required for MMP-2 and u-PA expression in SV40 large T-antigen-immortalized cells. Biochemical and Biophysical Research Communications. 297: 294-301. PMID 12237117 DOI: 10.1016/S0006-291X(02)02187-3  0.72
2002 Postovit LM, Adams MA, Lash GE, Heaton JP, Graham CH. Oxygen-mediated regulation of tumor cell invasiveness. Involvement of a nitric oxide signaling pathway. The Journal of Biological Chemistry. 277: 35730-7. PMID 12107174 DOI: 10.1074/jbc.M204529200  0.72
2002 Lash GE, Postovit LM, Matthews NE, Chung EY, Canning MT, Pross H, Adams MA, Graham CH. Oxygen as a regulator of cellular phenotypes in pregnancy and cancer. Canadian Journal of Physiology and Pharmacology. 80: 103-9. PMID 11934252 DOI: 10.1139/y02-008  0.72
2001 Canning MT, Postovit LM, Clarke SH, Graham CH. Oxygen-mediated regulation of gelatinase and tissue inhibitor of metalloproteinases-1 expression by invasive cells. Experimental Cell Research. 267: 88-94. PMID 11412041 DOI: 10.1006/excr.2001.5243  0.72
2001 Postovit LM, Adams MA, Graham CH. Does nitric oxide play a role in the aetiology of pre-eclampsia? Placenta. 22: S51-5. PMID 11312629 DOI: 10.1053/plac.2001.0636  0.72
2000 Graham CH, Postovit LM, Park H, Canning MT, Fitzpatrick TE. Adriana and Luisa Castellucci award lecture 1999: role of oxygen in the regulation of trophoblast gene expression and invasion. Placenta. 21: 443-50. PMID 10940194 DOI: 10.1053/plac.2000.0543  0.72
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