Richard P. Fahlman, Ph.D. - Publications

2001 Simon Fraser University, Burnaby, British Columbia, Canada 
Molecular Biology, Materials Science Engineering, General Biophysics, Biochemistry

34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Fung AW, Payoe R, Fahlman RP. Perspectives and Insights into the Competition for Aminoacyl-tRNAs between the Translational Machinery and for tRNA Dependent Non-Ribosomal Peptide Bond Formation. Life (Basel, Switzerland). 6. PMID 26729173 DOI: 10.3390/life6010002  1
2015 Khan SR, Aljuhani N, Morgan AG, Baghdasarian A, Fahlman RP, Siraki AG. Cytoprotective effect of isoniazid against H2O2 derived injury in HL-60 cells. Chemico-Biological Interactions. PMID 26658028 DOI: 10.1016/j.cbi.2015.11.026  1
2015 Lopez-Orozco J, Pare JM, Holme AL, Chaulk SG, Fahlman RP, Hobman TC. Functional analyses of phosphorylation events in human Argonaute 2. Rna (New York, N.Y.). 21: 2030-8. PMID 26443379 DOI: 10.1261/rna.053207.115  1
2015 Fung AW, Fahlman RP. The molecular basis for the post-translational addition of amino acids by L/F transferase in the N-end rule pathway. Current Protein & Peptide Science. 16: 163-80. PMID 25692952  1
2015 Patel A, Vasanthan V, Fu W, Fahlman RP, MacTavish D, Jhamandas JH. Histamine induces the production of matrix metalloproteinase-9 in human astrocytic cultures via H1-receptor subtype. Brain Structure & Function. PMID 25682263 DOI: 10.1007/s00429-015-1007-x  1
2015 Marcet-Palacios M, Ewen C, Pittman E, Duggan B, Carmine-Simmen K, Fahlman RP, Bleackley RC. Design and characterization of a novel human Granzyme B inhibitor. Protein Engineering, Design & Selection : Peds. 28: 9-17. PMID 25492933 DOI: 10.1093/protein/gzu052  1
2015 Chaulk SG, Ebhardt HA, Fahlman RP. Correlations of microRNA:microRNA expression patterns reveal insights into microRNA clusters and global microRNA expression patterns Molecular Biosystems. 12: 110-119. DOI: 10.1039/c5mb00415b  1
2014 Ebhardt HA, Nan J, Chaulk SG, Fahlman RP, Aebersold R. Enzymatic generation of peptides flanked by basic amino acids to obtain MS/MS spectra with 2× sequence coverage. Rapid Communications in Mass Spectrometry : Rcm. 28: 2735-43. PMID 25380496 DOI: 10.1002/rcm.7069  1
2014 Chaulk SG, Fahlman RP. Tertiary structure mapping of the pri-miRNA miR-17~92. Methods in Molecular Biology (Clifton, N.J.). 1182: 43-55. PMID 25055900 DOI: 10.1007/978-1-4939-1062-5_5  1
2014 Fung AW, Leung CC, Fahlman RP. The determination of tRNALeu recognition nucleotides for Escherichia coli L/F transferase. Rna (New York, N.Y.). 20: 1210-22. PMID 24935875 DOI: 10.1261/rna.044529.114  1
2014 Eldeeb MA, Fahlman RP. The anti-apoptotic form of tyrosine kinase Lyn that is generated by proteolysis is degraded by the N-end rule pathway. Oncotarget. 5: 2714-22. PMID 24798867 DOI: 10.18632/oncotarget.1931  1
2014 Fung AW, Ebhardt HA, Krishnakumar KS, Moore J, Xu Z, Strazewski P, Fahlman RP. Probing the leucyl/phenylalanyl tRNA protein transferase active site with tRNA substrate analogues. Protein and Peptide Letters. 21: 603-14. PMID 24521222 DOI: 10.2174/0929866521666140212110639  1
2014 Chaulk SG, Xu Z, Glover MJ, Fahlman RP. MicroRNA miR-92a-1 biogenesis and mRNA targeting is modulated by a tertiary contact within the miR-17~92 microRNA cluster. Nucleic Acids Research. 42: 5234-44. PMID 24520115 DOI: 10.1093/nar/gku133  1
2014 Chaulk SG, Lattanzi VJ, Hiemer SE, Fahlman RP, Varelas X. The Hippo pathway effectors TAZ/YAP regulate dicer expression and microRNA biogenesis through Let-7. The Journal of Biological Chemistry. 289: 1886-91. PMID 24324261 DOI: 10.1074/jbc.C113.529362  1
2014 Khan SR, Baghdasarian A, Fahlman RP, Michail K, Siraki AG. Current status and future prospects of toxicogenomics in drug discovery. Drug Discovery Today. 19: 562-78. PMID 24216320 DOI: 10.1016/j.drudis.2013.11.001  1
2014 Fahlman RP, Chen W, Overall CM. Absolute proteomic quantification of the activity state of proteases and proteolytic cleavages using proteolytic signature peptides and isobaric tags. Journal of Proteomics. 100: 79-91. PMID 24060996 DOI: 10.1016/j.jprot.2013.09.006  1
2014 Glaves JP, Li MX, Mercier P, Fahlman RP, Sykes BD. High-throughput, multi-platform metabolomics on very small volumes: 1H NMR metabolite identification in an unadulterated tube-in-tube system Metabolomics. DOI: 10.1007/s11306-014-0678-2  1
2012 Xu Z, Payoe R, Fahlman RP. The C-terminal proteolytic fragment of the breast cancer susceptibility type 1 protein (BRCA1) is degraded by the N-end rule pathway. The Journal of Biological Chemistry. 287: 7495-502. PMID 22262859 DOI: 10.1074/jbc.M111.301002  1
2011 Chaulk SG, Thede GL, Kent OA, Xu Z, Gesner EM, Veldhoen RA, Khanna SK, Goping IS, MacMillan AM, Mendell JT, Young HS, Fahlman RP, Glover JN. Role of pri-miRNA tertiary structure in miR-17~92 miRNA biogenesis. Rna Biology. 8: 1105-14. PMID 21955497 DOI: 10.4161/rna.8.6.17410  1
2011 Fung AW, Ebhardt HA, Abeysundara H, Moore J, Xu Z, Fahlman RP. An alternative mechanism for the catalysis of peptide bond formation by L/F transferase: substrate binding and orientation. Journal of Molecular Biology. 409: 617-29. PMID 21530538 DOI: 10.1016/j.jmb.2011.04.033  1
2011 Payoe R, Fahlman RP. Dependence of RelA-mediated (p)ppGpp formation on tRNA identity. Biochemistry. 50: 3075-83. PMID 21410133 DOI: 10.1021/bi1015309  1
2010 Ebhardt HA, Fedynak A, Fahlman RP. Naturally occurring variations in sequence length creates microRNA isoforms that differ in argonaute effector complex specificity. Silence. 1: 12. PMID 20534119 DOI: 10.1186/1758-907X-1-12  1
2009 Ebhardt HA, Tsang HH, Dai DC, Liu Y, Bostan B, Fahlman RP. Meta-analysis of small RNA-sequencing errors reveals ubiquitous post-transcriptional RNA modifications. Nucleic Acids Research. 37: 2461-70. PMID 19255090 DOI: 10.1093/nar/gkp093  1
2009 Ebhardt HA, Xu Z, Fung AW, Fahlman RP. Quantification of the post-translational addition of amino acids to proteins by MALDI-TOF mass spectrometry. Analytical Chemistry. 81: 1937-43. PMID 19186990 DOI: 10.1021/ac802423d  1
2009 Dale T, Fahlman RP, Olejniczak M, Uhlenbeck OC. Specificity of the ribosomal A site for aminoacyl-tRNAs. Nucleic Acids Research. 37: 1202-10. PMID 19129224 DOI: 10.1093/nar/gkn1040  1
2006 Fahlman RP, Olejniczak M, Uhlenbeck OC. Quantitative analysis of deoxynucleotide substitutions in the codon-anticodon helix. Journal of Molecular Biology. 355: 887-92. PMID 16343529 DOI: 10.1016/j.jmb.2005.11.011  1
2005 Olejniczak M, Dale T, Fahlman RP, Uhlenbeck OC. Idiosyncratic tuning of tRNAs to achieve uniform ribosome binding. Nature Structural & Molecular Biology. 12: 788-93. PMID 16116437 DOI: 10.1038/nsmb978  1
2004 Fahlman RP, Dale T, Uhlenbeck OC. Uniform binding of aminoacylated transfer RNAs to the ribosomal A and P sites. Molecular Cell. 16: 799-805. PMID 15574334 DOI: 10.1016/j.molcel.2004.10.030  1
2004 Fahlman RP, Uhlenbeck OC. Contribution of the esterified amino acid to the binding of aminoacylated tRNAs to the ribosomal P- and A-sites. Biochemistry. 43: 7575-83. PMID 15182199 DOI: 10.1021/bi0495836  1
2003 Fahlman RP, Hsing M, Sporer-Tuhten CS, Sen D. Duplex pinching: A structural switch suitable for contractile DNA nanoconstructions Nano Letters. 3: 1073-1078. DOI: 10.1021/nl034267i  1
2002 Fahlman RP, Sharma RD, Sen D. The charge conduction properties of DNA holliday junctions depend critically on the identity of the tethered photooxidant. Journal of the American Chemical Society. 124: 12477-85. PMID 12381189 DOI: 10.1021/ja020495n  1
2002 Fahlman RP, Sen D. DNA conformational switches as sensitive electronic sensors of analytes. Journal of the American Chemical Society. 124: 4610-6. PMID 11971708 DOI: 10.1021/ja012618u  1
1999 Fahlman RP, Sen D. 'Synapsable' DNA double helices: Self-selective modules for assembling DNA superstructures Journal of the American Chemical Society. 121: 11079-11085. DOI: 10.1021/ja992574d  1
1998 Fahlman RP, Sen D. Cation-regulated self-association of "synapsable" DNA duplexes. Journal of Molecular Biology. 280: 237-44. PMID 9654448 DOI: 10.1006/jmbi.1998.1875  1
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