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Ian M. Ahearn, Ph.D. - Publications

Affiliations: 
2010 Basic Medical Science New York University, New York, NY, United States 
Area:
Cell Biology
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21/27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Liang D, Jiang L, Bhat SA, Missiroli S, Perrone M, Lauriola A, Adhikari R, Gudur A, Vasi Z, Ahearn I, Guardavaccaro D, Giorgi C, Philips M, Kuchay S. Palmitoylation and PDE6δ regulate membrane-compartment-specific substrate ubiquitylation and degradation. Cell Reports. 42: 111999. PMID 36662618 DOI: 10.1016/j.celrep.2023.111999  0.563
2021 Deng J, Thennavan A, Dolgalev I, Chen T, Li J, Marzio A, Poirier JT, Peng D, Bulatovic M, Mukhopadhyay S, Silver H, Papadopoulos E, Pyon V, Thakurdin C, Han H, ... ... Ahearn I, et al. ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1 mutant lung cancer. Nature Cancer. 2: 503-514. PMID 34142094 DOI: 10.1038/s43018-021-00208-6  0.461
2021 Ahearn IM, Court HR, Siddiqui F, Abankwa D, Philips MR. NRAS is unique among RAS proteins in requiring ICMT for trafficking to the plasma membrane. Life Science Alliance. 4. PMID 33579760 DOI: 10.26508/lsa.202000972  0.744
2021 Chen X, Yao H, Kashif M, Revêchona G, Eriksson M, Hu J, Wang T, Liu Y, Tüksammel E, Strömblad S, Ahearn IM, Philips MR, Wiel C, Ibrahim MX, Bergo MO. A small-molecule ICMT inhibitor delays senescence of Hutchinson-Gilford progeria syndrome cells. Elife. 10. PMID 33526168 DOI: 10.7554/eLife.63284  0.525
2020 Zhou M, Kuruvilla L, Shi X, Viviano S, Ahearn IM, Amendola CR, Su W, Badri S, Mahaffey J, Fehrenbacher N, Skok J, Schlessinger J, Turk BE, Calderwood DA, Philips MR. Scaffold association factor B (SAFB) is required for expression of prenyltransferases and RAS membrane association. Proceedings of the National Academy of Sciences of the United States of America. PMID 33257571 DOI: 10.1073/pnas.2005712117  0.778
2019 Amendola CR, Mahaffey JP, Parker SJ, Ahearn IM, Chen WC, Zhou M, Court H, Shi J, Mendoza SL, Morten MJ, Rothenberg E, Gottlieb E, Wadghiri YZ, Possemato R, Hubbard SR, et al. KRAS4A directly regulates hexokinase 1. Nature. PMID 31827279 DOI: 10.1038/S41586-019-1832-9  0.719
2018 Ahearn I, Zhou M, Philips MR. Posttranslational Modifications of RAS Proteins. Cold Spring Harbor Perspectives in Medicine. PMID 29311131 DOI: 10.1101/Cshperspect.A031484  0.792
2017 Court H, Ahearn IM, Amoyel M, Bach EA, Philips MR. Regulation of NOTCH signaling by RAB7 and RAB8 requires carboxyl methylation by ICMT. The Journal of Cell Biology. PMID 29051265 DOI: 10.1083/Jcb.201701053  0.593
2016 Zhou M, Wiener H, Su W, Zhou Y, Liot C, Ahearn I, Hancock JF, Philips MR. VPS35 binds farnesylated N-Ras in the cytosol to regulate N-Ras trafficking. The Journal of Cell Biology. PMID 27502489 DOI: 10.1083/Jcb.201604061  0.819
2014 Tsai FD, Wynne JP, Ahearn IM, Philips MR. Metabolic labeling of Ras with tritiated palmitate to monitor palmitoylation and depalmitoylation. Methods in Molecular Biology (Clifton, N.J.). 1120: 33-41. PMID 24470017 DOI: 10.1007/978-1-62703-791-4_3  0.768
2012 Ahearn IM, Haigis K, Bar-Sagi D, Philips MR. Regulating the regulator: post-translational modification of RAS. Nature Reviews. Molecular Cell Biology. 13: 39-51. PMID 22189424 DOI: 10.1038/Nrm3255  0.77
2011 Villa CH, Dao T, Ahearn I, Fehrenbacher N, Casey E, Rey DA, Korontsvit T, Zakhaleva V, Batt CA, Philips MR, Scheinberg DA. Single-walled carbon nanotubes deliver peptide antigen into dendritic cells and enhance IgG responses to tumor-associated antigens. Acs Nano. 5: 5300-11. PMID 21682329 DOI: 10.1021/Nn200182X  0.531
2011 Ahearn IM, Tsai FD, Court H, Zhou M, Jennings BC, Ahmed M, Fehrenbacher N, Linder ME, Philips MR. FKBP12 binds to acylated H-ras and promotes depalmitoylation. Molecular Cell. 41: 173-85. PMID 21255728 DOI: 10.1016/J.Molcel.2011.01.001  0.822
2009 Mor A, Wynne JP, Ahearn IM, Dustin ML, Du G, Philips MR. Phospholipase D1 regulates lymphocyte adhesion via upregulation of Rap1 at the plasma membrane. Molecular and Cellular Biology. 29: 3297-306. PMID 19332557 DOI: 10.1128/Mcb.00366-09  0.782
2009 Wright LP, Court H, Mor A, Ahearn IM, Casey PJ, Philips MR. Topology of mammalian isoprenylcysteine carboxyl methyltransferase determined in live cells with a fluorescent probe. Molecular and Cellular Biology. 29: 1826-33. PMID 19158273 DOI: 10.1128/Mcb.01719-08  0.777
2008 Michaelson D, Abidi W, Guardavaccaro D, Zhou M, Ahearn I, Pagano M, Philips MR. Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division. The Journal of Cell Biology. 181: 485-96. PMID 18443222 DOI: 10.1083/Jcb.200801047  0.767
2008 Quatela SE, Sung PJ, Ahearn IM, Bivona TG, Philips MR. Analysis of K-Ras phosphorylation, translocation, and induction of apoptosis. Methods in Enzymology. 439: 87-102. PMID 18374158 DOI: 10.1016/S0076-6879(07)00407-7  0.804
2006 Bivona TG, Quatela SE, Bodemann BO, Ahearn IM, Soskis MJ, Mor A, Miura J, Wiener HH, Wright L, Saba SG, Yim D, Fein A, Pérez de Castro I, Li C, Thompson CB, et al. PKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis. Molecular Cell. 21: 481-93. PMID 16483930 DOI: 10.1016/J.Molcel.2006.01.012  0.733
2004 Bivona TG, Wiener HH, Ahearn IM, Silletti J, Chiu VK, Philips MR. Rap1 up-regulation and activation on plasma membrane regulates T cell adhesion. The Journal of Cell Biology. 164: 461-70. PMID 14757755 DOI: 10.1083/Jcb.200311093  0.772
2003 Bivona TG, Pérez De Castro I, Ahearn IM, Grana TM, Chiu VK, Lockyer PJ, Cullen PJ, Pellicer A, Cox AD, Philips MR. Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1. Nature. 424: 694-8. PMID 12845332 DOI: 10.1038/Nature01806  0.847
2003 Michaelson D, Ahearn I, Bergo M, Young S, Philips M. Membrane trafficking of heterotrimeric G proteins via the endoplasmic reticulum and Golgi. Molecular Biology of the Cell. 13: 3294-302. PMID 12221133 DOI: 10.1091/Mbc.E02-02-0095  0.688
Low-probability matches (unlikely to be authored by this person)
2019 Philips EA, Garcia-España A, Tocheva AS, Ahearn IM, Adam KR, Pan R, Mor A, Kong XP. The structural features that distinguish PD-L2 from PD-L1 emerged in placental mammals. The Journal of Biological Chemistry. PMID 31882544 DOI: 10.1074/Jbc.Ac119.011747  0.189
2001 Ranganathan V, Heine WF, Ciccone DN, Rudolph KL, Wu X, Chang S, Hai H, Ahearn IM, Livingston DM, Resnick I, Rosen F, Seemanova E, Jarolim P, DePinho RA, Weaver DT. Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit. Current Biology : Cb. 11: 962-6. PMID 11448772 DOI: 10.1016/S0960-9822(01)00267-6  0.083
2024 Philips EA, Liu J, Kvalvaag A, Mørch AM, Tocheva AS, Ng C, Liang H, Ahearn IM, Pan R, Luo CC, Leithner A, Qin Z, Zhou Y, Garcia-España A, Mor A, et al. Transmembrane domain-driven PD-1 dimers mediate T cell inhibition. Science Immunology. 9: eade6256. PMID 38457513 DOI: 10.1126/sciimmunol.ade6256  0.067
2014 Ahearn IM, Hu SW, Meehan SA, Latkowski JA. Primary cutaneous follicle-center lymphoma. Dermatology Online Journal. 20. PMID 25526329  0.042
2015 Ahearn IM, Gittler J, Shvartsbeyn M, Meehan SA, Pomeranz MK. Linear atrophoderma of Moulin. Dermatology Online Journal. 21. PMID 26990347  0.026
2023 Obijiofor C, Yin E, Shvartsbeyn M, Latkowski JA, Ahearn I, Gutierrez D. Tache and talon noir in patient with mycosis fungoides on acitretin. Dermatology Online Journal. 29. PMID 37921829 DOI: 10.5070/D329461918  0.01
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