E. Michael Ostap - Publications

Affiliations: 
University of Pennsylvania School of Medicine, Philadelphia, PA, United States 

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 De La Cruz EM, Blanchoin L, Ostap EM. Opening remarks from the Editors. Biophysical Reviews. 10: 1479-1480. PMID 30488377 DOI: 10.1007/S12551-018-0487-3  0.92
2016 Greenberg MJ, Arpağ G, Tüzel E, Ostap EM. A Perspective on the Role of Myosins as Mechanosensors. Biophysical Journal. 110: 2568-76. PMID 27332116 DOI: 10.1016/J.Bpj.2016.05.021  1
2016 Pyrpassopoulos S, Arpağ G, Feeser EA, Shuman H, Tüzel E, Ostap EM. Force Generation by Membrane-Associated Myosin-I. Scientific Reports. 6: 25524. PMID 27156719 DOI: 10.1016/J.Bpj.2015.11.2499  1
2015 Greenberg MJ, Lin T, Shuman H, Ostap EM. Mechanochemical tuning of myosin-I by the N-terminal region. Proceedings of the National Academy of Sciences of the United States of America. 112: E3337-44. PMID 26056287 DOI: 10.1073/Pnas.1506633112  1
2015 Kee AJ, Yang L, Lucas CA, Greenberg MJ, Martel N, Leong GM, Hughes WE, Cooney GJ, James DE, Ostap EM, Han W, Gunning PW, Hardeman EC. An actin filament population defined by the tropomyosin tpm3.1 regulates glucose uptake. Traffic (Copenhagen, Denmark). 16: 691-711. PMID 25783006 DOI: 10.1111/Tra.12282  1
2015 McIntosh BB, Holzbaur EL, Ostap EM. Control of the initiation and termination of kinesin-1-driven transport by myosin-Ic and nonmuscle tropomyosin. Current Biology : Cb. 25: 523-9. PMID 25660542 DOI: 10.1016/J.Cub.2014.12.008  1
2015 Kast DJ, Zajac AL, Holzbaur ELF, Ostap EM, Dominguez R. WHAMM Directs the Arp2/3 Complex to the ER for Autophagosome Biogenesis through an Actin Comet Tail Mechanism Current Biology. DOI: 10.1016/j.cub.2015.05.042  1
2014 Greenberg MJ, Shuman H, Ostap EM. Inherent force-dependent properties of β-cardiac myosin contribute to the force-velocity relationship of cardiac muscle. Biophysical Journal. 107: L41-4. PMID 25517169 DOI: 10.1016/J.Bpj.2014.11.005  1
2014 Ayloo S, Lazarus JE, Dodda A, Tokito M, Ostap EM, Holzbaur EL. Dynactin functions as both a dynamic tether and brake during dynein-driven motility. Nature Communications. 5: 4807. PMID 25185702 DOI: 10.1038/Ncomms5807  1
2014 Shuman H, Greenberg MJ, Zwolak A, Lin T, Sindelar CV, Dominguez R, Ostap EM. A vertebrate myosin-I structure reveals unique insights into myosin mechanochemical tuning. Proceedings of the National Academy of Sciences of the United States of America. 111: 2116-21. PMID 24469830 DOI: 10.1073/pnas.1321022111  1
2013 Pyrpassopoulos S, Shuman H, Ostap EM. Method for measuring single-molecule adhesion forces and attachment lifetimes of protein-membrane interactions. Methods in Molecular Biology (Clifton, N.J.). 1046: 389-403. PMID 23868602 DOI: 10.1007/978-1-62703-538-5_24  1
2013 Zajac AL, Goldman YE, Holzbaur EL, Ostap EM. Local cytoskeletal and organelle interactions impact molecular-motor- driven early endosomal trafficking. Current Biology : Cb. 23: 1173-80. PMID 23770188 DOI: 10.1016/J.Cub.2013.05.015  1
2013 Greenberg MJ, Ostap EM. Regulation and control of myosin-I by the motor and light chain-binding domains. Trends in Cell Biology. 23: 81-9. PMID 23200340 DOI: 10.1016/J.Tcb.2012.10.008  1
2012 Dawicki-McKenna JM, Goldman YE, Ostap EM. Sites of glucose transporter-4 vesicle fusion with the plasma membrane correlate spatially with microtubules. Plos One. 7: e43662. PMID 22916292 DOI: 10.1371/Journal.Pone.0043662  1
2012 Greenberg MJ, Lin T, Goldman YE, Shuman H, Ostap EM. Myosin IC generates power over a range of loads via a new tension-sensing mechanism. Proceedings of the National Academy of Sciences of the United States of America. 109: E2433-40. PMID 22908250 DOI: 10.1073/Pnas.1207811109  1
2012 Pyrpassopoulos S, Feeser EA, Mazerik JN, Tyska MJ, Ostap EM. Membrane-bound myo1c powers asymmetric motility of actin filaments. Current Biology : Cb. 22: 1688-92. PMID 22863317 DOI: 10.1016/J.Cub.2012.06.069  1
2012 Lewis JH, Greenberg MJ, Laakso JM, Shuman H, Ostap EM. Calcium regulation of myosin-I tension sensing. Biophysical Journal. 102: 2799-807. PMID 22735530 DOI: 10.1016/J.Bpj.2012.05.014  1
2012 Chen C, Greenberg MJ, Laakso JM, Ostap EM, Goldman YE, Shuman H. Kinetic schemes for post-synchronized single molecule dynamics. Biophysical Journal. 102: L23-5. PMID 22455931 DOI: 10.1016/J.Bpj.2012.01.054  1
2012 Goldman YE, Ostap EM. Myosin motors: Kinetics of myosin Comprehensive Biophysics. 4: 151-169. DOI: 10.1016/B978-0-12-374920-8.00411-2  1
2012 Goldman YE, Ostap EM. Introduction Comprehensive Biophysics. 4: 1-1. DOI: 10.1016/B978-0-12-374920-8.00401-X  1
2011 Lin T, Greenberg MJ, Moore JR, Ostap EM. A hearing loss-associated myo1c mutation (R156W) decreases the myosin duty ratio and force sensitivity. Biochemistry. 50: 1831-8. PMID 21265502 DOI: 10.1021/Bi1016777  1
2010 Feeser EA, Ignacio CM, Krendel M, Ostap EM. Myo1e binds anionic phospholipids with high affinity. Biochemistry. 49: 9353-60. PMID 20860408 DOI: 10.1021/Bi1012657  1
2010 Laakso JM, Lewis JH, Shuman H, Ostap EM. Control of myosin-I force sensing by alternative splicing Proceedings of the National Academy of Sciences of the United States of America. 107: 698-702. PMID 20080738 DOI: 10.1073/Pnas.0911426107  1
2010 Patino-Lopez G, Aravind L, Dong X, Kruhlak MJ, Ostap EM, Shaw S. Myosin 1G is an abundant class I myosin in lymphocytes whose localization at the plasma membrane depends on its ancient divergent pleckstrin homology (PH) domain (Myo1PH). The Journal of Biological Chemistry. 285: 8675-86. PMID 20071333 DOI: 10.1074/Jbc.M109.086959  1
2009 McKenna JM, Ostap EM. Kinetics of the interaction of myo1c with phosphoinositides. The Journal of Biological Chemistry. 284: 28650-9. PMID 19706607 DOI: 10.1074/Jbc.M109.049791  1
2009 Bethoney KA, King MC, Hinshaw JE, Ostap EM, Lemmon MA. A possible effector role for the pleckstrin homology (PH) domain of dynamin. Proceedings of the National Academy of Sciences of the United States of America. 106: 13359-64. PMID 19666604 DOI: 10.1073/Pnas.0906945106  1
2009 Sun Y, McKenna JD, Murray JM, Ostap EM, Goldman YE. Parallax: high accuracy three-dimensional single molecule tracking using split images. Nano Letters. 9: 2676-82. PMID 19496608 DOI: 10.1021/Nl901129J  1
2009 De La Cruz EM, Ostap EM. Kinetic and equilibrium analysis of the myosin ATPase. Methods in Enzymology. 455: 157-92. PMID 19289206 DOI: 10.1016/S0076-6879(08)04206-7  0.72
2008 Ostap EM. Tropomyosins as discriminators of myosin function. Advances in Experimental Medicine and Biology. 644: 273-82. PMID 19209828 DOI: 10.1007/978-0-387-85766-4_20  1
2008 Laakso JM, Lewis JH, Shuman H, Ostap EM. Myosin I can act as a molecular force sensor Science. 321: 133-136. PMID 18599791 DOI: 10.1126/Science.1159419  1
2007 Tang N, Lin T, Yang J, Foskett JK, Ostap EM. CIB1 and CaBP1 bind to the myo1c regulatory domain. Journal of Muscle Research and Cell Motility. 28: 285-91. PMID 17994197 DOI: 10.1007/S10974-007-9124-7  1
2007 Manceva S, Lin T, Pham H, Lewis JH, Goldman YE, Ostap EM. Calcium regulation of calmodulin binding to and dissociation from the myo1c regulatory domain. Biochemistry. 46: 11718-26. PMID 17910470 DOI: 10.1021/Bi700894H  1
2007 Bach TL, Kerr WT, Wang Y, Bauman EM, Kine P, Whiteman EL, Morgan RS, Williamson EK, Ostap EM, Burkhardt JK, Koretzky GA, Birnbaum MJ, Abrams CS. PI3K regulates pleckstrin-2 in T-cell cytoskeletal reorganization. Blood. 109: 1147-55. PMID 17008542 DOI: 10.1182/Blood-2006-02-001339  1
2006 Lewis JH, Lin T, Hokanson DE, Ostap EM. Temperature dependence of nucleotide association and kinetic characterization of myo1b. Biochemistry. 45: 11589-97. PMID 16981718 DOI: 10.1021/Bi0611917  1
2006 Hokanson DE, Laakso JM, Lin T, Sept D, Ostap EM. Myo1c binds phosphoinositides through a putative pleckstrin homology domain. Molecular Biology of the Cell. 17: 4856-65. PMID 16971510 DOI: 10.1091/Mbc.E06-05-0449  1
2006 Hokanson DE, Ostap EM. Myo1c binds tightly and specifically to phosphatidylinositol 4,5-bisphosphate and inositol 1,4,5-trisphosphate. Proceedings of the National Academy of Sciences of the United States of America. 103: 3118-23. PMID 16492791 DOI: 10.1073/Pnas.0505685103  1
2005 Lin T, Tang N, Ostap EM. Biochemical and motile properties of Myo1b splice isoforms. The Journal of Biological Chemistry. 280: 41562-7. PMID 16254000 DOI: 10.1074/Jbc.M508653200  1
2004 De La Cruz EM, Ostap EM. Relating biochemistry and function in the myosin superfamily. Current Opinion in Cell Biology. 16: 61-7. PMID 15037306 DOI: 10.1016/J.Ceb.2003.11.011  1
2003 Shaw MA, Ostap EM, Goldman YE. Mechanism of inhibition of skeletal muscle actomyosin by N-benzyl-p-toluenesulfonamide. Biochemistry. 42: 6128-35. PMID 12755615 DOI: 10.1021/Bi026964F  1
2003 Ostap EM, Maupin P, Doberstein SK, Baines IC, Korn ED, Pollard TD. Dynamic localization of myosin-I to endocytic structures in Acanthamoeba. Cell Motility and the Cytoskeleton. 54: 29-40. PMID 12451593 DOI: 10.1002/Cm.10081  1
2002 Ostap EM. 2,3-Butanedione monoxime (BDM) as a myosin inhibitor. Journal of Muscle Research and Cell Motility. 23: 305-8. PMID 12630704 DOI: 10.1023/A:1022047102064  1
2002 Ostap EM, Lin T, Rosenfeld SS, Tang N. Mechanism of regulation of Acanthamoeba myosin-IC by heavy-chain phosphorylation. Biochemistry. 41: 12450-6. PMID 12369835 DOI: 10.1021/Bi0262193  1
2002 Yengo CM, De la Cruz EM, Safer D, Ostap EM, Sweeney HL. Kinetic characterization of the weak binding states of myosin V. Biochemistry. 41: 8508-17. PMID 12081502 DOI: 10.1021/Bi015969U  1
2002 Andersen OS. The 55th Annual Meeting and Symposium of the Society of General Physiologists: molecular motors. The Journal of General Physiology. 119: 117-22. PMID 11815661 DOI: 10.1085/Jgp.119.2.117  1
2001 Tang N, Ostap EM. Motor domain-dependent localization of myo1b (myr-1). Current Biology : Cb. 11: 1131-5. PMID 11509238 DOI: 10.1016/S0960-9822(01)00320-7  1
2001 De La Cruz EM, Ostap EM, Sweeney HL. Kinetic mechanism and regulation of myosin VI. The Journal of Biological Chemistry. 276: 32373-81. PMID 11423557 DOI: 10.1074/Jbc.M104136200  1
2000 De La Cruz EM, Wells AL, Sweeney HL, Ostap EM. Actin and light chain isoform dependence of myosin V kinetics. Biochemistry. 39: 14196-202. PMID 11087368 DOI: 10.1021/Bi001701B  1
2000 De La Cruz EM, Sweeney HL, Ostap EM. ADP inhibition of myosin V ATPase activity. Biophysical Journal. 79: 1524-9. PMID 10969013 DOI: 10.1016/S0006-3495(00)76403-4  1
2000 De La Cruz EM, Ostap EM, Brundage RA, Reddy KS, Sweeney HL, Safer D. Thymosin-beta(4) changes the conformation and dynamics of actin monomers. Biophysical Journal. 78: 2516-27. PMID 10777749 DOI: 10.1016/S0006-3495(00)76797-X  1
1999 Lee WL, Ostap EM, Zot HG, Pollard TD. Organization and ligand binding properties of the tail of Acanthamoeba myosin-IA. Identification of an actin-binding site in the basic (tail homology-1) domain. The Journal of Biological Chemistry. 274: 35159-71. PMID 10574999 DOI: 10.1074/Jbc.274.49.35159  1
1999 De La Cruz EM, Wells AL, Rosenfeld SS, Ostap EM, Sweeney HL. The kinetic mechanism of myosin V. Proceedings of the National Academy of Sciences of the United States of America. 96: 13726-31. PMID 10570140 DOI: 10.1073/Pnas.96.24.13726  1
1998 Jontes JD, Ostap EM, Pollard TD, Milligan RA. Three-dimensional structure of Acanthamoeba castellanii myosin-IB (MIB) determined by cryoelectron microscopy of decorated actin filaments. The Journal of Cell Biology. 141: 155-62. PMID 9531555 DOI: 10.1083/Jcb.141.1.155  1
1997 Jontes JD, Milligan RA, Pollard TD, Ostap EM. Kinetic characterization of brush border myosin-I ATPase. Proceedings of the National Academy of Sciences of the United States of America. 94: 14332-7. PMID 9405612 DOI: 10.1073/pnas.94.26.14332  1
1996 Pollard TD, Ostap EM. The chemical mechanism of myosin-I: implications for actin-based motility and the evolution of the myosin family of motor proteins. Cell Structure and Function. 21: 351-6. PMID 9118240 DOI: 10.1247/Csf.21.351  1
1996 Ostap EM, Pollard TD. Overlapping functions of myosin-I isoforms? The Journal of Cell Biology. 133: 221-4. PMID 8609156 DOI: 10.1083/Jcb.133.2.221  1
1996 Ostap EM, Pollard TD. Biochemical kinetic characterization of the Acanthamoeba myosin-I ATPase. The Journal of Cell Biology. 132: 1053-60. PMID 8601584 DOI: 10.1083/Jcb.132.6.1053  1
1995 Thomas DD, Ramachandran S, Roopnarine O, Hayden DW, Ostap EM, Rayment I, Reisler K, Kinosita K. The mechanism of force generation in myosin: A disorder-to-order transition, coupled to internal structural changes Biophysical Journal. 68: 135s-141s. PMID 7787056  1
1995 Ostap EM, Barnett VA, Thomas DD. Resolution of three structural states of spin-labeled myosin in contracting muscle. Biophysical Journal. 69: 177-88. PMID 7669895 DOI: 10.1016/S0006-3495(95)79888-5  1
1993 Ostap EM, White HD, Thomas DD. Transient detection of spin-labeled myosin subfragment 1 conformational states during ATP hydrolysis. Biochemistry. 32: 6712-20. PMID 8392368 DOI: 10.1021/Bi00077A026  1
1993 Naber N, Ostap EM, Thomas DD, Cooke R. Orientation and rotational dynamics of spin-labeled phalloidin bound to actin in muscle fibers. Proteins. 17: 347-54. PMID 8108377 DOI: 10.1002/prot.340170403  1
1992 Ostap EM, Yanagida T, Thomas DD. Orientational distribution of spin-labeled actin oriented by flow. Biophysical Journal. 63: 966-75. PMID 1330042 DOI: 10.1016/S0006-3495(92)81684-3  1
1991 Ostap EM, Thomas DD. Rotational dynamics of spin-labeled F-actin during activation of myosin S1 ATPase using caged ATP. Biophysical Journal. 59: 1235-41. PMID 1651780 DOI: 10.1016/S0006-3495(91)82338-4  1
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