☰

Neal Castagnoli - Publications

Affiliations: 
1987 University of California, San Francisco, San Francisco, CA 
 1987- Virginia Polytechnic Institute and State University, Blacksburg, VA, United States 
Area:
Organic Chemistry, Pharmaceutical Chemistry, Biochemistry
Website:
https://chem.vt.edu/people/faculty/ncastagnoli.html
Tree Info Similar researchers PubMed Report error

90 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 Bergström MA, Isin EM, Castagnoli N, Milne CE. Bioactivation pathways of the cannabinoid receptor 1 antagonist rimonabant Drug Metabolism and Disposition. 39: 1823-1832. PMID 21733882 DOI: 10.1124/Dmd.111.039412  0.328
2010 Pretorius A, Ogunrombi MO, Fourie H, Terre'blanche G, Castagnoli N, Bergh JJ, Petzer JP. Interactions of 1-methyl-3-phenylpyrrolidine and 3-methyl-1-phenyl-3-azabicyclo[3.1.0]hexane with monoamine oxidase B. Bioorganic & Medicinal Chemistry. 18: 4111-8. PMID 20451395 DOI: 10.1016/J.Bmc.2010.03.079  0.373
2010 Mali'n TJ, Weidolf L, Castagnoli N, Jurva U. P450-catalyzed vs. electrochemical oxidation of haloperidol studied by ultra-performance liquid chromatography/electrospray ionization mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 24: 1231-40. PMID 20391593 DOI: 10.1002/Rcm.4505  0.349
2010 Strydom B, Malan SF, Castagnoli N, Bergh JJ, Petzer JP. Inhibition of monoamine oxidase by 8-benzyloxycaffeine analogues Bioorganic and Medicinal Chemistry. 18: 1018-1028. PMID 20093036 DOI: 10.1016/J.Bmc.2009.12.064  0.32
2009 Manley-King CI, Terre'Blanche G, Castagnoli N, Bergh JJ, Petzer JP. Inhibition of monoamine oxidase B by N-methyl-2-phenylmaleimides Bioorganic and Medicinal Chemistry. 17: 3104-3110. PMID 19324554 DOI: 10.1016/J.Bmc.2009.03.005  0.356
2008 Pretorius A, Ogunrombi MO, Terre'blanche G, Castagnoli N, Bergh JJ, Petzer JP. Deuterium isotope effects for the oxidation of 1-methyl-3-phenyl-3-pyrrolinyl analogues by monoamine oxidase B. Bioorganic & Medicinal Chemistry. 16: 8813-7. PMID 18799315 DOI: 10.1016/J.Bmc.2008.09.001  0.368
2006 Frédérick R, Dumont W, Ooms F, Aschenbach L, Van der Schyf CJ, Castagnoli N, Wouters J, Krief A. Synthesis, structural reassignment, and biological activity of type B MAO inhibitors based on the 5H-indeno[1,2-c]pyridazin-5-one core. Journal of Medicinal Chemistry. 49: 3743-7. PMID 16759116 DOI: 10.1021/Jm051091J  0.304
2005 Jurva U, Bissel P, Isin EM, Igarashi K, Kuttab S, Castagnoli N. Model electrochemical-mass spectrometric studies of the cytochrome P450-catalyzed oxidations of cyclic tertiary allylamines Journal of the American Chemical Society. 127: 12368-12377. PMID 16131218 DOI: 10.1021/Ja052048O  0.353
1999 Liu X, Zang L, Van der Schyf CJ, Igarashi K, Castagnoli K, Castagnoli N. Studies on the pyrrolinone metabolites derived from the tobacco alkaloid 1-methyl-2-(3-pyridinyl)pyrrole (beta-nicotyrine). Chemical Research in Toxicology. 12: 508-12. PMID 10368313 DOI: 10.1021/Tx990019J  0.348
1997 Palmer SL, Mabic S, Castagnoli N. Probing the active sites of monoamine oxidase A and B with 1,4-disubstituted tetrahydropyridine substrates and inactivators. Journal of Medicinal Chemistry. 40: 1982-9. PMID 9207939 DOI: 10.1021/Jm970079R  0.347
1997 Castagnoli K, Palmer S, Anderson A, Bueters T, Castagnoli N. The neuronal nitric oxide synthase inhibitor 7-nitroindazole also inhibits the monoamine oxidase-B-catalyzed oxidation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Chemical Research in Toxicology. 10: 364-8. PMID 9114971 DOI: 10.1021/Tx970001D  0.356
1997 Flaherty P, Castagnoli K, Wang YX, Castagnoli N. Synthesis and selective monoamine oxidase B-inhibiting properties of 1-methyl-1,2,3,6-tetrahydropyrid-4-yl carbamate derivatives: potential prodrugs of (R)- and (S)-nordeprenyl. Journal of Medicinal Chemistry. 39: 4756-61. PMID 8941389 DOI: 10.1021/Jm960477E  0.395
1996 Nimkar SK, Anderson AH, Rimoldi JM, Stanton M, Castagnoli KP, Mabic S, Wang YX, Castagnoli N. Synthesis and monoamine oxidase B catalyzed oxidation of C-4 heteroaromatic substituted 1,2,3,6-tetrahydropyridine derivatives. Chemical Research in Toxicology. 9: 1013-22. PMID 8870990 DOI: 10.1021/Tx960063O  0.397
1996 Usuki E, Pearce R, Parkinson A, Castagnoli N. Studies on the conversion of haloperidol and its tetrahydropyridine dehydration product to potentially neurotoxic pyridinium metabolites by human liver microsomes. Chemical Research in Toxicology. 9: 800-806. PMID 8831826 DOI: 10.1021/Tx960001Y  0.307
1996 Mabic S, Castagnoli N. Assessment of structural requirements for the monoamine oxidase-B-catalyzed oxidation of 1,4-disubstituted-1,2,3,6-tetrahydropyridine derivatives related to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Journal of Medicinal Chemistry. 39: 3694-700. PMID 8809158 DOI: 10.1021/Jm9603882  0.355
1996 Anderson AH, Kuttab S, Castagnoli N. Deuterium isotope effect studies on the MAO-B catalyzed oxidation of 4-benzyl-1-cyclopropyl-1,2,3,6-tetrahydropyridine. Biochemistry. 35: 3335-40. PMID 8605171 DOI: 10.1021/Bi9526701  0.377
1996 Mabic S, Castagnoli N. Selective Reductions of 1-Methyl-4-phenyl-2-pyridone Journal of Organic Chemistry. 61: 309-313. DOI: 10.1021/Jo951529V  0.329
1996 Avent K, Schyf CVd, Eyles D, Castagnoli N, Pond S. The quantitative analysis of a haloperidol derivative and its neurotoxic metabolites in baboons European Neuropsychopharmacology. 6: 37. DOI: 10.1016/0924-977X(96)87470-0  0.321
1995 Wang YX, Castagnoli N. Studies on the monoamine oxidase (MAO)-catalyzed oxidation of phenyl-substituted 1-methyl-4-phenoxy-1,2,3,6-tetrahydropyridine derivatives: factors contributing to MAO-A and MAO-B selectivity. Journal of Medicinal Chemistry. 38: 1904-10. PMID 7783122 DOI: 10.1021/Jm00011A010  0.365
1995 Kuttab S, Kalgutkar A, Castagnoli N. Mechanistic studies on the monoamine oxidase B catalyzed oxidation of 1,4-disubstituted tetrahydropyridines. Chemical Research in Toxicology. 7: 740-4. PMID 7696527 DOI: 10.1021/Tx00042A005  0.361
1995 Rimoldi JM, Wang YX, Nimkar SK, Kuttab SH, Anderson AH, Burch H, Castagnoli N. Probing the mechanism of bioactivation of MPTP type analogs by monoamine oxidase B: structure-activity studies on substituted 4-phenoxy-, 4-phenyl-, and 4-thiophenoxy-1-cyclopropyl-1,2,3,6-tetrahydropyridines. Chemical Research in Toxicology. 8: 703-10. PMID 7548753 DOI: 10.1021/Tx00047A010  0.365
1994 Kalgutkar AS, Castagnoli K, Hall A, Castagnoli N. Novel 4-(aryloxy)tetrahydropyridine analogs of MPTP as monoamine oxidase A and B substrates. Journal of Medicinal Chemistry. 37: 944-9. PMID 8151621 DOI: 10.1021/Jm00033A012  0.401
1992 Wu E, Shinka T, Caldera-Munoz P, Yoshizumi H, Trevor A, Castagnoli N. Metabolic studies on the nigrostriatal toxin MPTP and its MAO B generated dihydropyridinium metabolite MPDP+. Chemical Research in Toxicology. 1: 186-94. PMID 2979730 DOI: 10.1021/Tx00003A010  0.404
1992 Hoag MK, Schmidt-Peetz M, Lampen P, Trevor A, Castagnoli N. Metabolic studies on phencyclidine: characterization of a phencyclidine iminium ion metabolite. Chemical Research in Toxicology. 1: 128-31. PMID 2979720 DOI: 10.1021/Tx00002A007  0.371
1992 Zhao Z, Dalvie D, Naiman N, Castagnoli K, Castagnoli N. Design, synthesis, and biological evaluation of novel 4-substituted 1-methyl-1,2,3,6-tetrahydropyridine analogs of MPTP. Journal of Medicinal Chemistry. 35: 4473-8. PMID 1447747 DOI: 10.1021/Jm00101A026  0.398
1992 Hall L, Murray S, Castagnoli K, Castagnoli N. Studies on 1,2,3,6-tetrahydropyridine derivatives as potential monoamine oxidase inactivators. Chemical Research in Toxicology. 5: 625-33. PMID 1446001 DOI: 10.1021/Tx00029A006  0.375
1992 Kalgutkar AS, Castagnoli N. Synthesis of novel MPTP analogs as potential monoamine oxidase B (MAO-B) inhibitors. Journal of Medicinal Chemistry. 35: 4165-74. PMID 1433219 DOI: 10.1021/Jm00100A023  0.379
1992 Dalvie D, Zhao Z, Castagnoli N. Characterization of an unexpected product from a monoamine oxidase B generated 2,3-dihydropyridinium species The Journal of Organic Chemistry. 57: 7321-7324. DOI: 10.1021/Jo00052A056  0.381
1991 Naiman N, Rollema H, Johnson E, Castagnoli N. Studies on 4-benzyl-1-methyl-1,2,3,6-tetrahydropyridine, a nonneurotoxic analogue of the parkinsonian inducing agent 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Chemical Research in Toxicology. 3: 133-8. PMID 2130940 DOI: 10.1021/Tx00014A008  0.391
1991 Zhao ZY, Leung LY, Trevor A, Castagnoli N. C-formylation in the presence of rat brain mitochondria of the 2,3,4,5-tetrahydropyridinium metabolite derived from the psychotomimetic drug phencyclidine. Chemical Research in Toxicology. 4: 426-9. PMID 1912329 DOI: 10.1021/Tx00022A005  0.318
1991 Subramanyam B, Woolf T, Castagnoli N. Studies on the in vitro conversion of haloperidol to a potentially neurotoxic pyridinium metabolite. Chemical Research in Toxicology. 4: 123-8. PMID 1912294 DOI: 10.1021/Tx00019A017  0.412
1990 Rollema H, Johnson EA, Booth RG, Caldera P, Lampen P, Youngster SK, Trevor AJ, Naiman N, Castagnoli N. In vivo intracerebral microdialysis studies in rats of MPP+ analogues and related charged species. Journal of Medicinal Chemistry. 33: 2221-30. PMID 2374149 DOI: 10.1021/Jm00170A029  0.322
1990 Ottoboni S, Carlson TJ, Trager WF, Castagnoli K, Castagnoli N. Studies on the cytochrome P-450 catalyzed ring alpha-carbon oxidation of the nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Chemical Research in Toxicology. 3: 423-7. PMID 2133093 DOI: 10.1021/Tx00017A006  0.37
1989 Rollema H, Booth RG, Castagnoli N. In vivo dopaminergic neurotoxicity of the 2-beta-methylcarbolinium ion, a potential endogenous MPP+ analog. European Journal of Pharmacology. 153: 131-4. PMID 3265107 DOI: 10.1016/0014-2999(88)90597-3  0.31
1989 Booth RG, Castagnoli N, Rollema H. Intracerebral microdialysis neurotoxicity studies of quinoline and isoquinoline derivatives related to MPTP/MPP+. Neuroscience Letters. 100: 306-12. PMID 2788253 DOI: 10.1016/0304-3940(89)90704-0  0.359
1989 Booth RG, Trevor A, Singer TP, Castagnoli N. Studies on semirigid tricyclic analogues of the nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Journal of Medicinal Chemistry. 32: 473-7. PMID 2783613 DOI: 10.1021/Jm00122A031  0.372
1989 Hammock BD, Beale AM, Work T, Gee SJ, Gunther R, Higgins RJ, Shinka T, Castagnoli N. A sheep model for MPTP induced Parkinson-like symptoms. Life Sciences. 45: 1601-8. PMID 2586222 DOI: 10.1016/0024-3205(89)90427-X  0.308
1989 Leung L, Ottoboni S, Oppenheimer N, Castagnoli N. Characterization of a product derived from the 1-methyl-4-phenyl-2,3-dihydropyridinium ion, a metabolite of the nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine The Journal of Organic Chemistry. 54: 1052-1055. DOI: 10.1021/Jo00266A011  0.332
1988 Peterson LA, Castagnoli N. Regio- and stereochemical studies on the alpha-carbon oxidation of (S)-nicotine by cytochrome P-450 model systems. Journal of Medicinal Chemistry. 31: 637-40. PMID 3346880 DOI: 10.1021/Jm00398A024  0.321
1988 Trevor AJ, Castagnoli N, Singer TP. The formation of reactive intermediates in the MAO-catalyzed oxidation of the nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Toxicology. 49: 513-9. PMID 3287698 DOI: 10.1016/0300-483X(88)90037-6  0.384
1987 Peterson LA, Trevor A, Castagnoli N. Stereochemical studies on the cytochrome P-450 catalyzed oxidation of (S)-nicotine to the (S)-nicotine Δ1′(5′)-iminium species Journal of Medicinal Chemistry. 30: 249-254. PMID 3806608 DOI: 10.1021/Jm00385A004  0.372
1987 Shinka T, Castagnoli N, Wu EY, Hoag MK, Trevor AJ. Cation-exchange high-performance liquid chromatography assay for the nigrostriatal toxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and its monoamine oxidase B generated metabolites in brain tissues. Journal of Chromatography. 398: 279-87. PMID 3498735 DOI: 10.1016/S0021-9673(01)96513-6  0.341
1987 Di Monte D, Ekström G, Shinka T, Smith MT, Trevor AJ, Castagnoli N. Role of 1-methyl-4-phenylpyridinium ion formation and accumulation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity to isolated hepatocytes. Chemico-Biological Interactions. 62: 105-16. PMID 3496169 DOI: 10.1016/0009-2797(87)90083-4  0.354
1987 Trevor AJ, Castagnoli N, Caldera P, Ramsay RR, Singer TP. Bioactivation of MPTP: reactive metabolites and possible biochemical sequelae. Life Sciences. 40: 713-9. PMID 3492651 DOI: 10.1016/0024-3205(87)90298-0  0.385
1987 Shigenaga MK, Jacob P, Trevor A, Castagnoli N, Benowitz N. Synthesis of specifically labeled (S)-nicotine-5-3H and (S)-cotinine-5-3H BY carrier free tritiolysis of the corresponding 5-bromo derivatives Journal of Labelled Compounds and Radiopharmaceuticals. 24: 713-723. DOI: 10.1002/Jlcr.2580240614  0.303
1986 Dunn IS, Liberato DJ, Castagnoli N, Byers VS. Influence of chemical reactivity of urushiol-type haptens on sensitization and the induction of tolerance. Cellular Immunology. 97: 189-96. PMID 3742608 DOI: 10.1016/0008-8749(86)90388-6  0.3
1986 Krowech G, Caldera-Munoz PS, Straub K, Castagnoli N, Correia MA. Morphine metabolism revisited. III. Confirmation of a novel metabolic pathway. Chemico-Biological Interactions. 58: 29-40. PMID 3708721 DOI: 10.1016/S0009-2797(86)80084-9  0.353
1986 Wu EY, Chiba K, Trevor AJ, Castagnoli N. Interactions of the 1-methyl-4-phenyl-2,3-dihydropyridinium species with synthetic dopamine-melanin. Life Sciences. 39: 1695-700. PMID 3490611 DOI: 10.1016/0024-3205(86)90167-0  0.35
1986 Stampf JL, Benezra C, Byers V, Castagnoli N. Induction of tolerance to poison ivy urushiol in the guinea pig by epicutaneous application of the structural analog 5-methyl-3-n-pentadecylcatechol. The Journal of Investigative Dermatology. 86: 535-8. PMID 2943824 DOI: 10.1111/1523-1747.Ep12354978  0.32
1986 Ames JR, Brandänge S, Rodriguez B, Castagnoli N, Ryan MD, Kovacic P. Cyclic voltammetry with cyclic iminium ions: Implications for charge transfer with biomolecules (metabolites of nicotine, phencyclidine, and spermine) Bioorganic Chemistry. 14: 228-241. DOI: 10.1016/0045-2068(86)90034-9  0.342
1985 Peterson LA, Caldera PS, Trevor A, Chiba K, Castagnoli N. Studies on the 1-methyl-4-phenyl-2,3-dihydropyridinium Species 2,3-MPDP+, the monoamine oxidase catalyzed oxidation product of the nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) Journal of Medicinal Chemistry. 28: 1432-1436. PMID 3876442 DOI: 10.1002/Chin.198605331  0.379
1985 Weissman J, Trevor A, Chiba K, Peterson LA, Caldera P, Castagnoli N, Baillie T. Metabolism of the nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by liver homogenate fractions Journal of Medicinal Chemistry. 28: 997-1001. PMID 3874963 DOI: 10.1021/Jm00146A005  0.41
1985 Chiba K, Trevor AJ, Castagnoli N. Active uptake of MPP+, a metabolite of MPTP, by brain synaptosomes. Biochemical and Biophysical Research Communications. 128: 1228-32. PMID 3873939 DOI: 10.1016/0006-291X(85)91071-X  0.307
1985 Castagnoli N, Chiba K, Trevor AJ. Potential bioactivation pathways for the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Life Sciences. 36: 225-30. PMID 3871243 DOI: 10.1016/0024-3205(85)90063-3  0.413
1985 Reitz AB, Avery MA, Rosenkranz RP, Verlander MS, Melmon KL, Hoffman BB, Akita Y, Castagnoli N, Goodman M. Conjugates of catecholamines. 6. Synthesis and beta-adrenergic activity of N-(hydroxyalkyl)catecholamine derivatives. Journal of Medicinal Chemistry. 28: 642-7. PMID 2859373 DOI: 10.1021/Jm50001A018  0.356
1985 Reitz AB, Sonveaux E, Rosenkranz RP, Verlander MS, Melmon KL, Hoffman BB, Akita Y, Castagnoli N, Goodman M. Conjugates of catecholamines. 5. Synthesis and beta-adrenergic activity of N-(aminoalkyl)norepinephrine derivatives. Journal of Medicinal Chemistry. 28: 634-42. PMID 2859372 DOI: 10.1021/Jm50001A017  0.361
1985 REITZ AB, AVERY MA, ROSENKRANZ RP, VERLANDER MS, MELMON KL, HOFFMAN BB, AKITA Y, CASTAGNOLI N, GOODMAN M. ChemInform Abstract: CONJUGATES OF CATECHOLAMINES. 6. SYNTHESIS AND β-ADRENERGIC ACTIVITY OF N-(HYDROXYALKYL)CATECHOLAMINE DERIVATIVES Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198534180  0.32
1985 REITZ AB, SONVEAUX E, ROSENKRANZ RP, VERLANDER MS, MELMON KL, HOFFMAN BB, AKITA Y, CASTAGNOLI N, GOODMAN M. ChemInform Abstract: CONJUGATES OF CATECHOLAMINES. 5. SYNTHESIS AND β-ADRENERGIC ACTIVITY OF N-(AMINOALKYL)NOREPINEPHRINE DERIVATIVES Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198534179  0.321
1984 Correia MA, Krowech G, Caldera-Munoz P, Yee SL, Straub K, Castagnoli N. Morphine metabolism revisited. II. Isolation and chemical characterization of a glutathionylmorphine adduct from rat liver microsomal preparations. Chemico-Biological Interactions. 51: 13-24. PMID 6547643 DOI: 10.1016/0009-2797(84)90016-4  0.303
1984 Chiba K, Trevor A, Castagnoli N. Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase. Biochemical and Biophysical Research Communications. 120: 574-8. PMID 6428396 DOI: 10.1016/0006-291X(84)91293-2  0.331
1984 Cheng AC, Castagnoli N. Synthesis and physicochemical and neurotoxicity studies of 1-(4-substituted-2,5-dihydroxyphenyl)-2-aminoethane analogues of 6-hydroxydopamine Journal of Medicinal Chemistry. 27: 513-520. PMID 6423824 DOI: 10.1021/Jm00370A014  0.308
1984 Salach JI, Singer TP, Castagnoli N, Trevor A. Oxidation of the neurotoxic amine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by monoamine oxidases A and B and suicide inactivation of the enzymes by MPTP. Biochemical and Biophysical Research Communications. 125: 831-5. PMID 6335034 DOI: 10.1016/0006-291X(84)90614-4  0.378
1983 Dunn IS, Liberato DJ, Castagnoli N, Byers VS. Contact sensitivity to urushiol: role of covalent bond formation. Cellular Immunology. 74: 220-33. PMID 7165875 DOI: 10.1016/0008-8749(82)90023-5  0.311
1983 Rose J, Castagnoli N. The metabolism of tertiary amines. Medicinal Research Reviews. 3: 73-88. PMID 6341732 DOI: 10.1002/Med.2610030105  0.368
1982 Ziegler R, Ho B, Castagnoli N. Trapping of metabolically generated electrophilic species with cyanide ion: metabolism of methapyrilene. Journal of Medicinal Chemistry. 24: 1133-8. PMID 7328575 DOI: 10.1021/Jm00142A004  0.375
1982 Cheng AC, Shulgin AT, Castagnoli N. Studies on the chemical reactivity of the quinone methide derived from the oxidative cyclization of .alpha.-methyl-3,4-dihydroxyphenylalanine ethyl ester The Journal of Organic Chemistry. 47: 5258-5262. DOI: 10.1021/Jo00148A007  0.35
1981 Liberato DJ, Byers VS, Dennick RG, Castagnoli N. Regiospecific attack of nitrogen and sulfur nucleophiles on quinones derived from poison oak/ivy catechols (urushiols) and analogues as models for urushiol-protein conjugate formation. Journal of Medicinal Chemistry. 24: 28-33. PMID 7205871 DOI: 10.1021/Jm00133A007  0.331
1980 Ho B, Castagnoli N. Trapping of metabolically generated electrophilic species with cyanide ion: metabolism of 1-benzylpyrrolidine. Journal of Medicinal Chemistry. 23: 133-9. PMID 7359526 DOI: 10.1021/Jm00176A006  0.364
1980 Chavdarian CG, Castagnoli N. Synthesis, redox characteristics, and in vitro norepinephrine uptake inhibiting properties of 2-(2-mercapto-4,5-dihydroxyphenyl)ethylamine (6-mercaptodopamine). Journal of Medicinal Chemistry. 22: 1317-22. PMID 533879 DOI: 10.1021/Jm00197A008  0.34
1979 Jacob P, Kline T, Castagnoli N. Chemical and biological studies of 1-(2,5-dihydroxy-4-methylphenyl)-2-aminopropane, an analogue of 6-hydroxydopamine. Journal of Medicinal Chemistry. 22: 662-71. PMID 458821 DOI: 10.1021/Jm00192A011  0.357
1979 Nguyen TL, Gruenke LD, Castagnoli N. Metabolic oxidation of nicotine to chemically reactive intermediates. Journal of Medicinal Chemistry. 22: 259-63. PMID 423207 DOI: 10.1021/Jm00189A008  0.353
1978 Low LK, Castagnoli N. Chapter 31. Enantioselectivity in Drug Metabolism Annual Reports in Medicinal Chemistry. 13: 304-315. DOI: 10.1016/S0065-7743(08)60634-X  0.316
1977 Jacob P, Anderson G, Meshul CK, Shulgin AT, Castagnoli N. Monomethylthio analogues of 1-(2,4,5-trimethoxyphenyl)-2-aminopropane. Journal of Medicinal Chemistry. 20: 1235-9. PMID 903913 DOI: 10.1021/Jm00220A001  0.325
1977 Peter McGraw N, Callery PS, Castagnoli N. In vitro stereoselective metabolism of the psychotomimetic amine, 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane. An apparent enantiomeric interaction Journal of Medicinal Chemistry. 20: 185-189. PMID 836489 DOI: 10.1021/Jm00212A001  0.306
1976 Weinkam RJ, Gal J, Callery P, Castagnoli N. Application of chemical ionization mass spectrometry to the study of stereoselective in vitro metabolism of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane. Analytical Chemistry. 48: 203-9. PMID 1244761 DOI: 10.1021/Ac60365A058  0.308
1976 Jacob P, Callery PS, Shulgin AT, Castagnoli N. A convenient synthesis of quinones from hydroquinone dimethyl ethers. Oxidative demethylation with ceric ammonium nitrate Journal of Organic Chemistry. 41: 3627-3629. PMID 985642 DOI: 10.1021/Jo00884A035  0.349
1974 Cushman M, Castagnoli N. Synthesis of pharmacologically active nitrogen analogs of the tetrahydrocannabinols. The Journal of Organic Chemistry. 39: 1546-50. PMID 4833507 DOI: 10.1021/Jo00924A021  0.513
1974 Ames MM, Castagnoli N. The synthesis of13C-enriched α-methyldopa Journal of Labelled Compounds. 10: 195-205. DOI: 10.1002/Jlcr.2590100203  0.323
1973 Cushman M, Castagnoli N. A novel approach to the synthesis of nitrogen analogs of the tetrahydrocannabinols. The Journal of Organic Chemistry. 38: 440-8. PMID 4687212 DOI: 10.1021/Jo00943A007  0.491
1973 CASTAGNOLI N, SADEE W. ChemInform Abstract: MECHANISMEN DER RK. EINES 1,4-BENZODIAZEPIN-N-OXIDES MIT ACETANHYDRID Chemischer Informationsdienst. 4: no-no. DOI: 10.1002/chin.197306283  0.452
1972 Cushman M, Castagnoli N. The condensation of succinic anhydrides with Schiff bases. Scope and mechanism. The Journal of Organic Chemistry. 36: 3404-11. PMID 5132298 DOI: 10.1021/Jo00821A029  0.464
1972 Castagnoli N, Sadée W. Mechanism of the reaction of a 1,4-benzodiazepine N-oxide with acetic anhydride. Journal of Medicinal Chemistry. 15: 1076-8. PMID 5069778 DOI: 10.1021/Jm00280A024  0.511
1972 Dagne E, Castagnoli N. Cotinine N-oxide, a new metabolite of nicotine. Journal of Medicinal Chemistry. 15: 840-1. PMID 4625531 DOI: 10.1021/Jm00278A011  0.304
1972 Cushman M, Castagnoli N. Synthesis of trans-3'-methylnicotine The Journal of Organic Chemistry. 37: 1268-1271. DOI: 10.1021/Jo00973A046  0.495
1971 Sadèe W, Garland W, Castagnoli N. Microsomal 3-hydroxylation of 1,4-benzodiazepines. Journal of Medicinal Chemistry. 14: 643-5. PMID 5164455  0.46
1971 SADEE W, GARLAND W, CASTAGNOLI N. ChemInform Abstract: MIKROSOMALE 3-HYDROXYLIERUNG VON 1,4-BENZODIAZEPINEN Chemischer Informationsdienst. Organische Chemie. 2: no-no. DOI: 10.1002/chin.197143360  0.4
1969 Castagnoli N. The condensation of succinic anhydride with benzylidinemethylamine. A stereoselective synthesis of trans- and cis-1-methyl-4-carbosy-5-phenyl-2-pyrrolidinone. The Journal of Organic Chemistry. 34: 3187-9. PMID 5811404 DOI: 10.1021/Jo01262A081  0.315
1969 Castagnoli N, Melikian AP, Rosnati V. The synthesis of pyrrolidine-substituted nicotine analogs. Journal of Pharmaceutical Sciences. 58: 860-3. PMID 5810205 DOI: 10.1002/Jps.2600580715  0.346
1964 Rapoport H, Castagnoli N, Holden KG. 2,2':5',2″-Terpyrrole1a The Journal of Organic Chemistry. 29: 883-885. DOI: 10.1021/Jo01027A029  0.415
1962 Rapoport H, Castagnoli N. 2,2″-Bipyrrole Journal of the American Chemical Society. 84: 2178-2181. DOI: 10.1021/Ja00870A032  0.34
Show low-probability matches.