Year |
Citation |
Score |
2015 |
Luan B, Yoon YS, Le Lay J, Kaestner KH, Hedrick S, Montminy M. CREB pathway links PGE2 signaling with macrophage polarization. Proceedings of the National Academy of Sciences of the United States of America. PMID 26644581 DOI: 10.1073/pnas.1519644112 |
0.32 |
|
2015 |
Hogan MF, Ravnskjaer K, Matsumura S, Huising MO, Hull RL, Kahn SE, Montminy M. Hepatic Insulin Resistance Following Chronic Activation of the CREB Coactivator CRTC2. The Journal of Biological Chemistry. 290: 25997-6006. PMID 26342077 DOI: 10.1074/jbc.M115.679266 |
0.32 |
|
2015 |
Hernandez JB, Chang C, LeBlanc M, Grimm D, Le Lay J, Kaestner KH, Zheng Y, Montminy M. The CREB/CRTC2 pathway modulates autoimmune disease by promoting Th17 differentiation. Nature Communications. 6: 7216. PMID 26031354 DOI: 10.1038/ncomms8216 |
0.32 |
|
2015 |
Tsai WW, Matsumura S, Liu W, Phillips NG, Sonntag T, Hao E, Lee S, Hai T, Montminy M. ATF3 mediates inhibitory effects of ethanol on hepatic gluconeogenesis. Proceedings of the National Academy of Sciences of the United States of America. 112: 2699-704. PMID 25730876 DOI: 10.1073/pnas.1424641112 |
0.32 |
|
2015 |
Blanchet E, Van de Velde S, Matsumura S, Hao E, LeLay J, Kaestner K, Montminy M. Feedback inhibition of CREB signaling promotes beta cell dysfunction in insulin resistance. Cell Reports. 10: 1149-57. PMID 25704817 DOI: 10.1016/j.celrep.2015.01.046 |
0.32 |
|
2014 |
Paz JC, Park S, Phillips N, Matsumura S, Tsai WW, Kasper L, Brindle PK, Zhang G, Zhou MM, Wright PE, Montminy M. Combinatorial regulation of a signal-dependent activator by phosphorylation and acetylation. Proceedings of the National Academy of Sciences of the United States of America. 111: 17116-21. PMID 25404345 DOI: 10.1073/pnas.1420389111 |
0.32 |
|
2014 |
Luan B, Goodarzi MO, Phillips NG, Guo X, Chen YD, Yao J, Allison M, Rotter JI, Shaw R, Montminy M. Leptin-mediated increases in catecholamine signaling reduce adipose tissue inflammation via activation of macrophage HDAC4. Cell Metabolism. 19: 1058-65. PMID 24768298 DOI: 10.1016/j.cmet.2014.03.024 |
0.32 |
|
2013 |
Tsai WW, Niessen S, Goebel N, Yates JR, Guccione E, Montminy M. PRMT5 modulates the metabolic response to fasting signals. Proceedings of the National Academy of Sciences of the United States of America. 110: 8870-5. PMID 23671120 DOI: 10.1073/pnas.1304602110 |
0.32 |
|
2013 |
Yu J, Deng R, Zhu HH, Zhang SS, Zhu C, Montminy M, Davis R, Feng GS. Modulation of fatty acid synthase degradation by concerted action of p38 MAP kinase, E3 ligase COP1, and SH2-tyrosine phosphatase Shp2. The Journal of Biological Chemistry. 288: 3823-30. PMID 23269672 DOI: 10.1074/jbc.M112.397885 |
0.32 |
|
2012 |
Luo Q, Viste K, Urday-Zaa JC, Senthil Kumar G, Tsai WW, Talai A, Mayo KE, Montminy M, Radhakrishnan I. Mechanism of CREB recognition and coactivation by the CREB-regulated transcriptional coactivator CRTC2. Proceedings of the National Academy of Sciences of the United States of America. 109: 20865-70. PMID 23213254 DOI: 10.1073/pnas.1219028109 |
0.32 |
|
2012 |
Wang Y, Li G, Goode J, Paz JC, Ouyang K, Screaton R, Fischer WH, Chen J, Tabas I, Montminy M. Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes. Nature. 485: 128-32. PMID 22495310 DOI: 10.1038/nature10988 |
0.32 |
|
2012 |
Montminy M, Lee KF, Rivier JE, Rivier C, Reichlin S. Wylie Vale: neuroendocrine master. Proceedings of the National Academy of Sciences of the United States of America. 109: 3604-5. PMID 22355104 DOI: 10.1073/pnas.1201696109 |
0.32 |
|
2011 |
Stewart R, Flechner L, Montminy M, Berdeaux R. CREB is activated by muscle injury and promotes muscle regeneration. Plos One. 6: e24714. PMID 21931825 DOI: 10.1371/journal.pone.0024714 |
0.32 |
|
2011 |
Mihaylova MM, Vasquez DS, Ravnskjaer K, Denechaud PD, Yu RT, Alvarez JG, Downes M, Evans RM, Montminy M, Shaw RJ. Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis. Cell. 145: 607-21. PMID 21565617 DOI: 10.1016/j.cell.2011.03.043 |
0.32 |
|
2011 |
Wang B, Moya N, Niessen S, Hoover H, Mihaylova MM, Shaw RJ, Yates JR, Fischer WH, Thomas JB, Montminy M. A hormone-dependent module regulating energy balance. Cell. 145: 596-606. PMID 21565616 DOI: 10.1016/j.cell.2011.04.013 |
0.32 |
|
2011 |
Mair W, Morantte I, Rodrigues AP, Manning G, Montminy M, Shaw RJ, Dillin A. Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB. Nature. 470: 404-8. PMID 21331044 DOI: 10.1038/nature09706 |
0.32 |
|
2010 |
Song Y, Altarejos J, Goodarzi MO, Inoue H, Guo X, Berdeaux R, Kim JH, Goode J, Igata M, Paz JC, Hogan MF, Singh PK, Goebel N, Vera L, Miller N, ... ... Montminy M, et al. CRTC3 links catecholamine signalling to energy balance. Nature. 468: 933-9. PMID 21164481 DOI: 10.1038/nature09564 |
0.32 |
|
2010 |
Yoon YS, Lee MW, Ryu D, Kim JH, Ma H, Seo WY, Kim YN, Kim SS, Lee CH, Hunter T, Choi CS, Montminy MR, Koo SH. Suppressor of MEK null (SMEK)/protein phosphatase 4 catalytic subunit (PP4C) is a key regulator of hepatic gluconeogenesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 17704-9. PMID 20876121 DOI: 10.1073/pnas.1012665107 |
0.32 |
|
2010 |
Zhang EE, Liu Y, Dentin R, Pongsawakul PY, Liu AC, Hirota T, Nusinow DA, Sun X, Landais S, Kodama Y, Brenner DA, Montminy M, Kay SA. Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis. Nature Medicine. 16: 1152-6. PMID 20852621 DOI: 10.1038/nm.2214 |
0.32 |
|
2010 |
Zmuda EJ, Qi L, Zhu MX, Mirmira RG, Montminy MR, Hai T. The roles of ATF3, an adaptive-response gene, in high-fat-diet-induced diabetes and pancreatic beta-cell dysfunction. Molecular Endocrinology (Baltimore, Md.). 24: 1423-33. PMID 20519332 DOI: 10.1210/me.2009-0463 |
0.32 |
|
2009 |
Qi L, Saberi M, Zmuda E, Wang Y, Altarejos J, Zhang X, Dentin R, Hedrick S, Bandyopadhyay G, Hai T, Olefsky J, Montminy M. Adipocyte CREB promotes insulin resistance in obesity. Cell Metabolism. 9: 277-86. PMID 19254572 DOI: 10.1016/j.cmet.2009.01.006 |
0.32 |
|
2009 |
Ryu D, Oh KJ, Jo HY, Hedrick S, Kim YN, Hwang YJ, Park TS, Han JS, Choi CS, Montminy M, Koo SH. TORC2 regulates hepatic insulin signaling via a mammalian phosphatidic acid phosphatase, LIPIN1. Cell Metabolism. 9: 240-51. PMID 19254569 DOI: 10.1016/j.cmet.2009.01.007 |
0.32 |
|
2009 |
Altarejos J, Goebel N, Conkright M, Inoue H, Xie J, Arias C, Sawchenko P, Montminy M. Reply to: Mouse fertility is not dependent on the CREB coactivator Crtc1 Nature Medicine. 15: 991. DOI: 10.1038/nm0909-991a |
0.32 |
|
2008 |
Liu Y, Dentin R, Chen D, Hedrick S, Ravnskjaer K, Schenk S, Milne J, Meyers DJ, Cole P, Yates J, Olefsky J, Guarente L, Montminy M. A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange. Nature. 456: 269-73. PMID 18849969 DOI: 10.1038/nature07349 |
0.32 |
|
2008 |
Altarejos JY, Goebel N, Conkright MD, Inoue H, Xie J, Arias CM, Sawchenko PE, Montminy M. The Creb1 coactivator Crtc1 is required for energy balance and fertility. Nature Medicine. 14: 1112-7. PMID 18758446 DOI: 10.1038/nm.1866 |
0.32 |
|
2008 |
Wang B, Goode J, Best J, Meltzer J, Schilman PE, Chen J, Garza D, Thomas JB, Montminy M. The insulin-regulated CREB coactivator TORC promotes stress resistance in Drosophila. Cell Metabolism. 7: 434-44. PMID 18460334 DOI: 10.1016/j.cmet.2008.02.010 |
0.32 |
|
2007 |
Dentin R, Liu Y, Koo SH, Hedrick S, Vargas T, Heredia J, Yates J, Montminy M. Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2. Nature. 449: 366-9. PMID 17805301 DOI: 10.1038/nature06128 |
0.32 |
|
2007 |
Ravnskjaer K, Kester H, Liu Y, Zhang X, Lee D, Yates JR, Montminy M. Cooperative interactions between CBP and TORC2 confer selectivity to CREB target gene expression. The Embo Journal. 26: 2880-9. PMID 17476304 DOI: 10.1038/sj.emboj.7601715 |
0.32 |
|
2007 |
Berdeaux R, Goebel N, Banaszynski L, Takemori H, Wandless T, Shelton GD, Montminy M. SIK1 is a class II HDAC kinase that promotes survival of skeletal myocytes. Nature Medicine. 13: 597-603. PMID 17468767 DOI: 10.1038/nm1573 |
0.32 |
|
2006 |
Qi L, Heredia JE, Altarejos JY, Screaton R, Goebel N, Niessen S, Macleod IX, Liew CW, Kulkarni RN, Bain J, Newgard C, Nelson M, Evans RM, Yates J, Montminy M. TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism. Science (New York, N.Y.). 312: 1763-6. PMID 16794074 DOI: 10.1126/science.1123374 |
0.32 |
|
2006 |
Cho CY, Koo SH, Wang Y, Callaway S, Hedrick S, Mak PA, Orth AP, Peters EC, Saez E, Montminy M, Schultz PG, Chanda SK. Identification of the tyrosine phosphatase PTP-MEG2 as an antagonist of hepatic insulin signaling. Cell Metabolism. 3: 367-78. PMID 16679294 DOI: 10.1016/j.cmet.2006.03.006 |
0.32 |
|
2006 |
Zhang W, Patil S, Chauhan B, Guo S, Powell DR, Le J, Klotsas A, Matika R, Xiao X, Franks R, Heidenreich KA, Sajan MP, Farese RV, Stolz DB, Tso P, ... ... Montminy M, et al. FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression. The Journal of Biological Chemistry. 281: 10105-17. PMID 16492665 DOI: 10.1074/jbc.M600272200 |
0.32 |
|
2006 |
Koo SH, Montminy M. Fatty acids and insulin resistance: a perfect storm. Molecular Cell. 21: 449-50. PMID 16483925 DOI: 10.1016/j.molcel.2006.02.001 |
0.32 |
|
2005 |
Shaw RJ, Lamia KA, Vasquez D, Koo SH, Bardeesy N, Depinho RA, Montminy M, Cantley LC. The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin. Science (New York, N.Y.). 310: 1642-6. PMID 16308421 DOI: 10.1126/science.1120781 |
0.32 |
|
2005 |
Canettieri G, Koo SH, Berdeaux R, Heredia J, Hedrick S, Zhang X, Montminy M. Dual role of the coactivator TORC2 in modulating hepatic glucose output and insulin signaling. Cell Metabolism. 2: 331-8. PMID 16271533 DOI: 10.1016/j.cmet.2005.09.008 |
0.32 |
|
2005 |
Gardner KH, Montminy M. Can you hear me now? Regulating transcriptional activators by phosphorylation. Science's Stke : Signal Transduction Knowledge Environment. 2005: pe44. PMID 16160121 DOI: 10.1126/stke.3012005pe44 |
0.32 |
|
2005 |
Koo SH, Flechner L, Qi L, Zhang X, Screaton RA, Jeffries S, Hedrick S, Xu W, Boussouar F, Brindle P, Takemori H, Montminy M. The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism. Nature. 437: 1109-11. PMID 16148943 DOI: 10.1038/nature03967 |
0.32 |
|
2005 |
Zhang X, Odom DT, Koo SH, Conkright MD, Canettieri G, Best J, Chen H, Jenner R, Herbolsheimer E, Jacobsen E, Kadam S, Ecker JR, Emerson B, Hogenesch JB, Unterman T, ... ... Montminy M, et al. Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues. Proceedings of the National Academy of Sciences of the United States of America. 102: 4459-64. PMID 15753290 DOI: 10.1073/pnas.0501076102 |
0.32 |
|
2004 |
Best JL, Amezcua CA, Mayr B, Flechner L, Murawsky CM, Emerson B, Zor T, Gardner KH, Montminy M. Identification of small-molecule antagonists that inhibit an activator: coactivator interaction. Proceedings of the National Academy of Sciences of the United States of America. 101: 17622-7. PMID 15585582 DOI: 10.1073/pnas.0406374101 |
0.32 |
|
2004 |
Screaton RA, Conkright MD, Katoh Y, Best JL, Canettieri G, Jeffries S, Guzman E, Niessen S, Yates JR, Takemori H, Okamoto M, Montminy M. The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector. Cell. 119: 61-74. PMID 15454081 DOI: 10.1016/j.cell.2004.09.015 |
0.32 |
|
2004 |
Koo SH, Satoh H, Herzig S, Lee CH, Hedrick S, Kulkarni R, Evans RM, Olefsky J, Montminy M. PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3. Nature Medicine. 10: 530-4. PMID 15107844 DOI: 10.1038/nm1044 |
0.32 |
|
2003 |
Herzig S, Hedrick S, Morantte I, Koo SH, Galimi F, Montminy M. CREB controls hepatic lipid metabolism through nuclear hormone receptor PPAR-gamma. Nature. 426: 190-3. PMID 14614508 DOI: 10.1038/nature02110 |
0.32 |
|
2002 |
Zor T, Mayr BM, Dyson HJ, Montminy MR, Wright PE. Roles of phosphorylation and helix propensity in the binding of the KIX domain of CREB-binding protein by constitutive (c-Myb) and inducible (CREB) activators. The Journal of Biological Chemistry. 277: 42241-8. PMID 12196545 DOI: 10.1074/jbc.M207361200 |
0.32 |
|
2002 |
Kushner JA, Ye J, Schubert M, Burks DJ, Dow MA, Flint CL, Dutta S, Wright CV, Montminy MR, White MF. Pdx1 restores beta cell function in Irs2 knockout mice. The Journal of Clinical Investigation. 109: 1193-201. PMID 11994408 DOI: 10.1172/JCI14439 |
0.32 |
|
2001 |
Xu W, Chen H, Du K, Asahara H, Tini M, Emerson BM, Montminy M, Evans RM. A transcriptional switch mediated by cofactor methylation. Science (New York, N.Y.). 294: 2507-11. PMID 11701890 DOI: 10.1126/science.1065961 |
0.32 |
|
2001 |
Asahara H, Santoso B, Guzman E, Du K, Cole PA, Davidson I, Montminy M. Chromatin-dependent cooperativity between constitutive and inducible activation domains in CREB. Molecular and Cellular Biology. 21: 7892-900. PMID 11689682 DOI: 10.1128/MCB.21.23.7892-7900.2001 |
0.32 |
|
2001 |
Herzig S, Long F, Jhala US, Hedrick S, Quinn R, Bauer A, Rudolph D, Schutz G, Yoon C, Puigserver P, Spiegelman B, Montminy M. CREB regulates hepatic gluconeogenesis through the coactivator PGC-1. Nature. 413: 179-83. PMID 11557984 DOI: 10.1038/35093131 |
0.32 |
|
2000 |
von Mikecz A, Zhang S, Montminy M, Tan EM, Hemmerich P. CREB-binding protein (CBP)/p300 and RNA polymerase II colocalize in transcriptionally active domains in the nucleus. The Journal of Cell Biology. 150: 265-73. PMID 10893273 DOI: 10.1083/jcb.150.1.265 |
0.32 |
|
1999 |
Malecki MT, Jhala US, Antonellis A, Fields L, Doria A, Orban T, Saad M, Warram JH, Montminy M, Krolewski AS. Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus Nature Genetics. 23: 323-328. PMID 10545951 DOI: 10.1038/15500 |
0.32 |
|
1999 |
Parker D, Rivera M, Zor T, Henrion-Caude A, Radhakrishnan I, Kumar A, Shapiro LH, Wright PE, Montminy M, Brindle PK. Role of secondary structure in discrimination between constitutive and inducible activators. Molecular and Cellular Biology. 19: 5601-7. PMID 10409749 DOI: 10.1128/MCB.19.8.5601 |
0.32 |
|
1998 |
Du K, Montminy M. CREB is a regulatory target for the protein kinase Akt/PKB Journal of Biological Chemistry. 273: 32377-32379. PMID 9829964 DOI: 10.1074/jbc.273.49.32377 |
0.32 |
|
1998 |
Blobel GA, Nakajima T, Eckner R, Montminy M, Orkin SH. CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiation Proceedings of the National Academy of Sciences of the United States of America. 95: 2061-2066. PMID 9482838 DOI: 10.1073/pnas.95.5.2061 |
0.32 |
|
1997 |
Nakajima T, Uchida C, Anderson SF, Chee-Gun L, Hurwitz J, Parvin JD, Montminy M. RNA helicase A mediates association of CBP with RNA polymerase II Cell. 90: 1107-1112. PMID 9323138 DOI: 10.1016/S0092-8674(00)80376-1 |
0.32 |
|
1996 |
Chakravarti D, LaMorte VJ, Nelson MC, Nakajima T, Schulman IG, Juguilon H, Montminy M, Evans RM. Role of CBP/P300 in nuclear receptor signalling. Nature. 383: 99-103. PMID 8779723 DOI: 10.1038/383099a0 |
0.32 |
|
1995 |
Brindle P, Nakajima T, Montminy M. Multiple protein kinase A-regulated events are required for transcriptional induction by cAMP Proceedings of the National Academy of Sciences of the United States of America. 92: 10521-10525. PMID 7479832 DOI: 10.1073/pnas.92.23.10521 |
0.32 |
|
1994 |
Arias J, Alberts AS, Brindle P, Claret FX, Smeal T, Karin M, Feramisco J, Montminy M. Activation of cAMP and mitogen responsive genes relies on a common nuclear factor. Nature. 370: 226-9. PMID 8028671 DOI: 10.1038/370226a0 |
0.32 |
|
1994 |
Ferreri K, Gill G, Montminy M. The cAMP-regulated transcription factor CREB interacts with a component of the TFIID complex Proceedings of the National Academy of Sciences of the United States of America. 91: 1210-1213. PMID 7906413 DOI: 10.1073/pnas.91.4.1210 |
0.32 |
|
1993 |
Brindle P, Linke S, Montminy M. Protein-kinase-A-dependent activator in transcription factor CREB reveals new role for CREM repressors Nature. 364: 821-824. PMID 8102791 DOI: 10.1038/364821a0 |
0.32 |
|
1993 |
Meinkoth JL, Alberts AS, Went W, Fantozzi D, Taylor SS, Hagiwara M, Montminy M, Feramisco JR. Signal transduction through the cAMP-dependent protein kinase. Molecular and Cellular Biochemistry. 127: 179-86. PMID 7935349 DOI: 10.1007/BF01076769 |
0.32 |
|
1992 |
Brindle PK, Montminy MR. The CREB family of transcription activators. Current Opinion in Genetics & Development. 2: 199-204. PMID 1386267 DOI: 10.1016/S0959-437X(05)80274-6 |
0.32 |
|
1992 |
Hagiwara M, Alberts A, Brindle P, Meinkoth J, Feramisco J, Deng T, Karin M, Shenolikar S, Montminy M. Transcriptional attenuation following cAMP induction requires PP-1-mediated dephosphorylation of CREB. Cell. 70: 105-13. PMID 1352481 DOI: 10.1016/0092-8674(92)90537-M |
0.32 |
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