| Year |
Citation |
Score |
| 2022 |
Kashiwagi M, Figueroa DS, Ay F, Morgan BA, Georgopoulos K. A double-negative thymocyte-specific enhancer augments Notch1 signaling to direct early T cell progenitor expansion, lineage restriction and β-selection. Nature Immunology. PMID 36316479 DOI: 10.1038/s41590-022-01322-y |
0.409 |
|
| 2021 |
Lazarian G, Yin S, Ten Hacken E, Sewastianik T, Uduman M, Font-Tello A, Gohil SH, Li S, Kim E, Joyal H, Billington L, Witten E, Zheng M, Huang T, Severgnini M, ... ... Georgopoulos K, et al. A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation. Cancer Cell. 39: 380-393.e8. PMID 33689703 DOI: 10.1016/j.ccell.2021.02.003 |
0.336 |
|
| 2020 |
Shibata S, Kashiwagi M, Morgan BA, Georgopoulos K. Functional interactions between Mi-2β and AP1 complexes control response and recovery from skin barrier disruption. The Journal of Experimental Medicine. 217. PMID 31834931 DOI: 10.1084/Jem.20182402 |
0.329 |
|
| 2019 |
Yoshida T, Hu Y, Zhang Z, Emmanuel AO, Galani K, Muhire B, Snippert HJ, Williams CJ, Tolstorukov MY, Gounari F, Georgopoulos K. Chromatin restriction by the nucleosome remodeler Mi-2β and functional interplay with lineage-specific transcription regulators control B-cell differentiation. Genes & Development. PMID 31123064 DOI: 10.1101/Gad.321901.118 |
0.463 |
|
| 2019 |
Murthy V, Tebaldi T, Yoshida T, Erdin S, Calzonetti T, Vijayvargia R, Tripathi T, Kerschbamer E, Seong IS, Quattrone A, Talkowski ME, Gusella JF, Georgopoulos K, MacDonald ME, Biagioli M. Hypomorphic mutation of the mouse Huntington's disease gene orthologue. Plos Genetics. 15: e1007765. PMID 30897080 DOI: 10.1371/Journal.Pgen.1007765 |
0.348 |
|
| 2018 |
McClatchey AI, Georgopoulos K. Actin' Up to Stop SNFin Out TEAD. Developmental Cell. 47: 693-695. PMID 30562513 DOI: 10.1016/J.Devcel.2018.11.037 |
0.304 |
|
| 2018 |
Lazarian G, Yin S, Font-tello A, Ten Hacken E, Sevastianik T, Tom D, Regis FF, Gill A, Zheng M, Georgopoulos K, Neuberg DS, Wang L, Carrasco RD, Wu CJ. KZF-L162R Mutation Affects Splenic Mature B Cell Development and Alters Expression of Aiolos Target Genes Blood. 132: 668-668. DOI: 10.1182/Blood-2018-99-115483 |
0.463 |
|
| 2017 |
Hu Y, Yoshida T, Georgopoulos K. Transcriptional circuits in B cell transformation. Current Opinion in Hematology. PMID 28463873 DOI: 10.1097/Moh.0000000000000352 |
0.424 |
|
| 2017 |
Georgopoulos K. The making of a lymphocyte: the choice among disparate cell fates and the IKAROS enigma. Genes & Development. 31: 439-450. PMID 28385788 DOI: 10.1101/Gad.297002.117 |
0.473 |
|
| 2017 |
Georgopoulos K. In search of the mechanism that shapes the neutrophil's nucleus. Genes & Development. 31: 85-87. PMID 28202537 DOI: 10.1101/Gad.296228.117 |
0.35 |
|
| 2017 |
Kashiwagi M, Hosoi J, Lai JF, Brissette J, Ziegler SF, Morgan BA, Georgopoulos K. Direct control of regulatory T cells by keratinocytes. Nature Immunology. PMID 28092372 DOI: 10.1038/Ni.3661 |
0.386 |
|
| 2016 |
Hayakawa M, Hayakawa H, Petrova T, Ritprajak P, Sutavani RV, Jiménez-Andrade GY, Sano Y, Choo MK, Seavitt J, Venigalla RK, Otsu K, Georgopoulos K, Arthur JS, Park JM. Loss of functionally redundant p38 isoforms in T cells enhances regulatory T cell induction. The Journal of Biological Chemistry. PMID 28011639 DOI: 10.1074/Jbc.M116.764548 |
0.444 |
|
| 2016 |
Hu Y, Zhang Z, Kashiwagi M, Yoshida T, Joshi I, Jena N, Somasundaram R, Emmanuel AO, Sigvardsson M, Fitamant J, El-Bardeesy N, Gounari F, Van Etten RA, Georgopoulos K. Superenhancer reprogramming drives a B-cell-epithelial transition and high-risk leukemia. Genes & Development. 30: 1971-90. PMID 27664237 DOI: 10.1101/Gad.283762.116 |
0.503 |
|
| 2016 |
Georgopoulos K. Induction of Bcl11b during T cell commitment through a tripartite mechanism. Nature Immunology. 17: 903-4. PMID 27434004 DOI: 10.1038/Ni.3520 |
0.475 |
|
| 2016 |
Etten RV, Hu Y, Zhang Z, Yoshida T, Jena N, Kashiwagi M, Joshi I, El-Bardeesy N, Somasundaram R, Sigvardsson M, Liu Z, Tata P, Korber S, Raufi A, Krause D, ... ... Georgopoulos K, et al. Central role for ikaros in pre-B cell differentiation and pathogenesis of high-risk B-cell acute lymphoblastic leukemia Experimental Hematology. 44. DOI: 10.1016/J.Exphem.2016.06.024 |
0.37 |
|
| 2015 |
Perotti EA, Georgopoulos K, Yoshida T. An Ikaros Promoter Element with Dual Epigenetic and Transcriptional Activities. Plos One. 10: e0131568. PMID 26135129 DOI: 10.1371/Journal.Pone.0131568 |
0.419 |
|
| 2015 |
Georgopoulos K. Ebf1 in DNA repair and leukemogenesis. Blood. 125: 3969-71. PMID 26113531 DOI: 10.1182/Blood-2015-05-639427 |
0.48 |
|
| 2015 |
Jena N, Joshi I, Yoshida T, Zhang Z, Liu Z, Tata P, Shapiro IM, Pachter JA, Weaver DT, Georgopoulos K, Etten RAV. Abstract 4202: Targeting focal adhesion kinase is a novel approach to therapy of high-risk, Ikaros-mutant acute B-cell lymphoblastic leukemia Cancer Research. 75: 4202-4202. DOI: 10.1158/1538-7445.Am2015-4202 |
0.379 |
|
| 2014 |
Yoshida T, Georgopoulos K. Ikaros fingers on lymphocyte differentiation. International Journal of Hematology. 100: 220-9. PMID 25085254 DOI: 10.1007/S12185-014-1644-5 |
0.555 |
|
| 2014 |
Yamada T, Yang Y, Hemberg M, Yoshida T, Cho HY, Murphy JP, Fioravante D, Regehr WG, Gygi SP, Georgopoulos K, Bonni A. Promoter decommissioning by the NuRD chromatin remodeling complex triggers synaptic connectivity in the mammalian brain. Neuron. 83: 122-34. PMID 24991957 DOI: 10.1016/J.Neuron.2014.05.039 |
0.398 |
|
| 2014 |
Joshi I, Yoshida T, Jena N, Qi X, Zhang J, Van Etten RA, Georgopoulos K. Loss of Ikaros DNA-binding function confers integrin-dependent survival on pre-B cells and progression to acute lymphoblastic leukemia. Nature Immunology. 15: 294-304. PMID 24509510 DOI: 10.1038/Ni.2821 |
0.434 |
|
| 2014 |
Dose M, Emmanuel AO, Chaumeil J, Zhang J, Sun T, Germar K, Aghajani K, Davis EM, Keerthivasan S, Bredemeyer AL, Sleckman BP, Rosen ST, Skok JA, Le Beau MM, Georgopoulos K, et al. β-Catenin induces T-cell transformation by promoting genomic instability. Proceedings of the National Academy of Sciences of the United States of America. 111: 391-6. PMID 24371308 DOI: 10.1073/Pnas.1315752111 |
0.424 |
|
| 2014 |
Joshi I, Jena N, Yoshida T, Paraskevopoulou L, Zhang Z, Liu Z, Korber S, Krause DS, Shapiro IM, Weaver DT, Pachter JA, Paietta EM, Van Etten RA, Georgopoulos K. Focal Adhesion Kinase Inhibitors Reverse the Stromal Adhesion Phenotype of Ikaros-Mutant B-ALL, Induce Apopotosis, and Synergize with ABL1 Tyrosine Kinase Inhibitors: A New Paradigm for Pathogenesis and Therapy of High-Risk B-ALL Blood. 124: 285-285. DOI: 10.1182/Blood.V124.21.285.285 |
0.382 |
|
| 2013 |
Yoshida T, Georgopoulos K. GATA-3 controls self-renewal in stressed HSCs. Nature Immunology. 14: 1032-3. PMID 24048133 DOI: 10.1038/Ni.2715 |
0.365 |
|
| 2013 |
Yoshida T, Landhuis E, Dose M, Hazan I, Zhang J, Naito T, Jackson AF, Wu J, Perotti EA, Kaufmann C, Gounari F, Morgan BA, Georgopoulos K. Transcriptional regulation of the Ikzf1 locus. Blood. 122: 3149-59. PMID 24002445 DOI: 10.1182/Blood-2013-01-474916 |
0.733 |
|
| 2013 |
Jena N, Joshi I, Yoshida T, Qi X, Zhang J, Georgopoulos K, Etten RAV. Ikaros Mutation Confers Integrin-Dependent Survival Of Pre-B Cells and Progression To Acute Lymphoblastic Leukemia Blood. 122: 1259-1259. DOI: 10.1182/Blood.V122.21.1259.1259 |
0.441 |
|
| 2012 |
Quintana FJ, Jin H, Burns EJ, Nadeau M, Yeste A, Kumar D, Rangachari M, Zhu C, Xiao S, Seavitt J, Georgopoulos K, Kuchroo VK. Aiolos promotes TH17 differentiation by directly silencing Il2 expression. Nature Immunology. 13: 770-7. PMID 22751139 DOI: 10.1038/Ni.2363 |
0.396 |
|
| 2012 |
Han R, Beppu H, Lee YK, Georgopoulos K, Larue L, Li E, Weiner L, Brissette JL. A pair of transmembrane receptors essential for the retention and pigmentation of hair. Genesis (New York, N.Y. : 2000). 50: 783-800. PMID 22611050 DOI: 10.1002/Dvg.22039 |
0.358 |
|
| 2012 |
MartÃn-Ibáñez R, Crespo E, Esgleas M, Urban N, Wang B, Waclaw R, Georgopoulos K, MartÃnez S, Campbell K, Vicario-Abejón C, Alberch J, Chan S, Kastner P, Rubenstein JL, Canals JM. Helios transcription factor expression depends on Gsx2 and Dlx1&2 function in developing striatal matrix neurons. Stem Cells and Development. 21: 2239-51. PMID 22142223 DOI: 10.1089/Scd.2011.0607 |
0.386 |
|
| 2012 |
Zhang J, Jackson AF, Naito T, Dose M, Seavitt J, Liu F, Heller EJ, Kashiwagi M, Yoshida T, Gounari F, Petrie HT, Georgopoulos K. Harnessing of the nucleosome-remodeling-deacetylase complex controls lymphocyte development and prevents leukemogenesis. Nature Immunology. 13: 86-94. PMID 22080921 DOI: 10.1038/Ni.2150 |
0.472 |
|
| 2011 |
Harker N, Garefalaki A, Menzel U, Ktistaki E, Naito T, Georgopoulos K, Kioussis D. Pre-TCR signaling and CD8 gene bivalent chromatin resolution during thymocyte development. Journal of Immunology (Baltimore, Md. : 1950). 186: 6368-77. PMID 21515796 DOI: 10.4049/Jimmunol.1003567 |
0.342 |
|
| 2010 |
Gómez-del Arco P, Kashiwagi M, Jackson AF, Naito T, Zhang J, Liu F, Kee B, Vooijs M, Radtke F, Redondo JM, Georgopoulos K. Alternative promoter usage at the Notch1 locus supports ligand-independent signaling in T cell development and leukemogenesis. Immunity. 33: 685-98. PMID 21093322 DOI: 10.1016/J.Immuni.2010.11.008 |
0.502 |
|
| 2010 |
Yoshida T, Ng SY, Georgopoulos K. Awakening lineage potential by Ikaros-mediated transcriptional priming. Current Opinion in Immunology. 22: 154-60. PMID 20299195 DOI: 10.1016/J.Coi.2010.02.011 |
0.441 |
|
| 2010 |
MartÃn-Ibáñez R, Crespo E, Urbán N, Sergent-Tanguy S, Herranz C, Jaumot M, Valiente M, Long JE, Pineda JR, Andreu C, Rubenstein JL, MarÃn O, Georgopoulos K, Mengod G, Fariñas I, et al. Ikaros-1 couples cell cycle arrest of late striatal precursors with neurogenesis of enkephalinergic neurons. The Journal of Comparative Neurology. 518: 329-51. PMID 19950118 DOI: 10.1002/Cne.22215 |
0.316 |
|
| 2009 |
Mandal M, Powers SE, Ochiai K, Georgopoulos K, Kee BL, Singh H, Clark MR. Ras orchestrates exit from the cell cycle and light-chain recombination during early B cell development. Nature Immunology. 10: 1110-7. PMID 19734904 DOI: 10.1038/Ni.1785 |
0.426 |
|
| 2009 |
Ng SY, Yoshida T, Zhang J, Georgopoulos K. Genome-wide lineage-specific transcriptional networks underscore Ikaros-dependent lymphoid priming in hematopoietic stem cells. Immunity. 30: 493-507. PMID 19345118 DOI: 10.1016/J.Immuni.2009.01.014 |
0.483 |
|
| 2009 |
Georgopoulos K. From immunity to tolerance through HDAC. Nature Immunology. 10: 13-4. PMID 19088734 DOI: 10.1038/Ni0109-13 |
0.431 |
|
| 2008 |
Yoshida T, Hazan I, Zhang J, Ng SY, Naito T, Snippert HJ, Heller EJ, Qi X, Lawton LN, Williams CJ, Georgopoulos K. The role of the chromatin remodeler Mi-2beta in hematopoietic stem cell self-renewal and multilineage differentiation. Genes & Development. 22: 1174-89. PMID 18451107 DOI: 10.1101/Gad.1642808 |
0.435 |
|
| 2007 |
Naito T, Gómez-Del Arco P, Williams CJ, Georgopoulos K. Antagonistic interactions between Ikaros and the chromatin remodeler Mi-2beta determine silencer activity and Cd4 gene expression. Immunity. 27: 723-34. PMID 17980631 DOI: 10.1016/J.Immuni.2007.09.008 |
0.425 |
|
| 2007 |
Kioussis D, Georgopoulos K. Epigenetic flexibility underlying lineage choices in the adaptive immune system. Science (New York, N.Y.). 317: 620-2. PMID 17673651 DOI: 10.1126/Science.1143777 |
0.378 |
|
| 2007 |
Agoston DV, Szemes M, Dobi A, Palkovits M, Georgopoulos K, Gyorgy A, Ring MA. Ikaros is expressed in developing striatal neurons and involved in enkephalinergic differentiation. Journal of Neurochemistry. 102: 1805-16. PMID 17504264 DOI: 10.1111/J.1471-4159.2007.04653.X |
0.443 |
|
| 2007 |
Thompson EC, Cobb BS, Sabbattini P, Meixlsperger S, Parelho V, Liberg D, Taylor B, Dillon N, Georgopoulos K, Jumaa H, Smale ST, Fisher AG, Merkenschlager M. Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits. Immunity. 26: 335-44. PMID 17363301 DOI: 10.1016/J.Immuni.2007.02.010 |
0.471 |
|
| 2007 |
Kashiwagi M, Morgan BA, Georgopoulos K. The chromatin remodeler Mi-2beta is required for establishment of the basal epidermis and normal differentiation of its progeny. Development (Cambridge, England). 134: 1571-82. PMID 17360773 DOI: 10.1242/Dev.001750 |
0.315 |
|
| 2007 |
Ng SY, Yoshida T, Georgopoulos K. Ikaros and chromatin regulation in early hematopoiesis. Current Opinion in Immunology. 19: 116-22. PMID 17307348 DOI: 10.1016/J.Coi.2007.02.014 |
0.422 |
|
| 2006 |
Yoshida T, Ng SY, Zuniga-Pflucker JC, Georgopoulos K. Early hematopoietic lineage restrictions directed by Ikaros. Nature Immunology. 7: 382-91. PMID 16518393 DOI: 10.1038/Ni1314 |
0.405 |
|
| 2006 |
Ueda Y, Okano M, Williams C, Chen T, Georgopoulos K, Li E. Roles for Dnmt3b in mammalian development: a mouse model for the ICF syndrome. Development (Cambridge, England). 133: 1183-92. PMID 16501171 DOI: 10.1242/Dev.02293 |
0.325 |
|
| 2005 |
Liu E, Sinha S, Williams C, Cyrille M, Heller E, Snapper SB, Georgopoulos K, St-Arnaud R, Force T, Dedhar S, Gerszten RE. Targeted deletion of integrin-linked kinase reveals a role in T-cell chemotaxis and survival. Molecular and Cellular Biology. 25: 11145-55. PMID 16314534 DOI: 10.1128/Mcb.25.24.11145-11155.2005 |
0.405 |
|
| 2005 |
Gómez-del Arco P, Koipally J, Georgopoulos K. Ikaros SUMOylation: switching out of repression. Molecular and Cellular Biology. 25: 2688-97. PMID 15767674 DOI: 10.1128/Mcb.25.7.2688-2697.2005 |
0.417 |
|
| 2004 |
Williams CJ, Naito T, Arco PG, Seavitt JR, Cashman SM, De Souza B, Qi X, Keables P, Von Andrian UH, Georgopoulos K. The chromatin remodeler Mi-2beta is required for CD4 expression and T cell development. Immunity. 20: 719-33. PMID 15189737 DOI: 10.1016/J.Immuni.2004.05.005 |
0.451 |
|
| 2004 |
Gómez-del Arco P, Maki K, Georgopoulos K. Phosphorylation controls Ikaros's ability to negatively regulate the G(1)-S transition. Molecular and Cellular Biology. 24: 2797-807. PMID 15024069 DOI: 10.1128/Mcb.24.7.2797-2807.2004 |
0.323 |
|
| 2004 |
Cortés M, Georgopoulos K. Aiolos is required for the generation of high affinity bone marrow plasma cells responsible for long-term immunity. The Journal of Experimental Medicine. 199: 209-19. PMID 14718515 DOI: 10.1084/Jem.20031571 |
0.34 |
|
| 2003 |
Kaufmann C, Yoshida T, Perotti EA, Landhuis E, Wu P, Georgopoulos K. A complex network of regulatory elements in Ikaros and their activity during hemo-lymphopoiesis. The Embo Journal. 22: 2211-23. PMID 12727887 DOI: 10.1093/Emboj/Cdg186 |
0.702 |
|
| 2003 |
Sun J, Matthias G, Mihatsch MJ, Georgopoulos K, Matthias P. Lack of the transcriptional coactivator OBF-1 prevents the development of systemic lupus erythematosus-like phenotypes in Aiolos mutant mice. Journal of Immunology (Baltimore, Md. : 1950). 170: 1699-706. PMID 12574333 DOI: 10.4049/Jimmunol.170.4.1699 |
0.433 |
|
| 2002 |
Harker N, Naito T, Cortes M, Hostert A, Hirschberg S, Tolaini M, Roderick K, Georgopoulos K, Kioussis D. The CD8alpha gene locus is regulated by the Ikaros family of proteins. Molecular Cell. 10: 1403-15. PMID 12504015 DOI: 10.1016/S1097-2765(02)00711-6 |
0.418 |
|
| 2002 |
Koipally J, Georgopoulos K. A molecular dissection of the repression circuitry of Ikaros. The Journal of Biological Chemistry. 277: 27697-705. PMID 12015313 DOI: 10.1074/Jbc.M201694200 |
0.368 |
|
| 2002 |
Koipally J, Georgopoulos K. Ikaros-CtIP interactions do not require C-terminal binding protein and participate in a deacetylase-independent mode of repression. The Journal of Biological Chemistry. 277: 23143-9. PMID 11959865 DOI: 10.1074/Jbc.M202079200 |
0.389 |
|
| 2002 |
Georgopoulos K. Haematopoietic cell-fate decisions, chromatin regulation and ikaros. Nature Reviews. Immunology. 2: 162-74. PMID 11913067 DOI: 10.1038/Nri747 |
0.446 |
|
| 2002 |
Koipally J, Heller EJ, Seavitt JR, Georgopoulos K. Unconventional potentiation of gene expression by Ikaros. The Journal of Biological Chemistry. 277: 13007-15. PMID 11799125 DOI: 10.1074/Jbc.M111371200 |
0.454 |
|
| 2002 |
DiFronzo NL, Leung CT, Mammel MK, Georgopoulos K, Taylor BJ, Pham QN. Ikaros, a lymphoid-cell-specific transcription factor, contributes to the leukemogenic phenotype of a mink cell focus-inducing murine leukemia virus. Journal of Virology. 76: 78-87. PMID 11739673 DOI: 10.1128/Jvi.76.1.78-87.2002 |
0.438 |
|
| 2001 |
Cariappa A, Tang M, Parng C, Nebelitskiy E, Carroll M, Georgopoulos K, Pillai S. The follicular versus marginal zone B lymphocyte cell fate decision is regulated by Aiolos, Btk, and CD21 Immunity. 14: 603-615. PMID 11371362 DOI: 10.1016/S1074-7613(01)00135-2 |
0.406 |
|
| 2001 |
Wu L, Vandenabeele S, Georgopoulos K. Derivation of dendritic cells from myeloid and lymphoid precursors. International Reviews of Immunology. 20: 117-135. PMID 11342301 DOI: 10.3109/08830180109056726 |
0.349 |
|
| 2001 |
Yamada A, Takaki S, Hayashi F, Georgopoulos K, Perlmutter RM, Takatsu K. Identification and characterization of a transcriptional regulator for the lck proximal promoter Journal of Biological Chemistry. 276: 18082-18089. PMID 11278409 DOI: 10.1074/Jbc.M008387200 |
0.507 |
|
| 2000 |
Koipally J, Georgopoulos K. Ikaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activity. Journal of Biological Chemistry. 275: 19594-19602. PMID 10766745 DOI: 10.1074/Jbc.M000254200 |
0.419 |
|
| 2000 |
Galy A, Christopherson I, Ferlazzo G, Liu G, Spits H, Georgopoulos K. Distinct signals control the hematopoiesis of lymphoid-related dendritic cells Blood. 95: 128-137. DOI: 10.1182/Blood.V95.1.128.001K06_128_137 |
0.323 |
|
| 1999 |
Koipally J, Kim J, Jones B, Jackson A, Avitahl N, Winandy S, Trevisan M, Nichogiannopoulou A, Kelley C, Georgopoulos K. Ikaros chromatin remodeling complexes in the control of differentiation of the hemo-lymphoid system Cold Spring Harbor Symposia On Quantitative Biology. 64: 79-86. PMID 11232340 DOI: 10.1101/Sqb.1999.64.79 |
0.33 |
|
| 1999 |
Nichogiannopoulou A, Trevisan M, Neben S, Friedrich C, Georgopoulos K. Defects in Hemopoietic Stem Cell Activity in Ikaros Mutant Mice Journal of Experimental Medicine. 190: 1201-1214. PMID 10544193 DOI: 10.1084/Jem.190.9.1201 |
0.399 |
|
| 1999 |
Winandy S, Wu L, Wang J, Georgopoulos K. Pre-T cell receptor (TCR) and TCR-controlled checkpoints in T cell differentiation are set by Ikaros. Journal of Experimental Medicine. 190: 1039-1048. PMID 10523602 DOI: 10.1084/Jem.190.8.1039 |
0.466 |
|
| 1999 |
Koipally J, Renold A, Kim J, Georgopoulos K. Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes Embo Journal. 18: 3090-3100. PMID 10357820 DOI: 10.1093/Emboj/18.11.3090 |
0.41 |
|
| 1999 |
Cortes M, Wong E, Koipally J, Georgopoulos K. Control of lymphocyte development by the Ikaros gene family. Current Opinion in Immunology. 11: 167-171. PMID 10322160 DOI: 10.1016/S0952-7915(99)80028-4 |
0.527 |
|
| 1999 |
Kim J, Sif S, Jones B, Jackson A, Koipally J, Heller E, Winandy S, Viel A, Sawyer A, Ikeda T, Kingston R, Georgopoulos K. Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes. Immunity. 10: 345-55. PMID 10204490 DOI: 10.1016/S1074-7613(00)80034-5 |
0.436 |
|
| 1999 |
Avitahl N, Winandy S, Friedrich C, Jones B, Ge Y, Georgopoulos K. Ikaros sets thresholds for T cell activation and regulates chromosome propagation. Immunity. 10: 333-43. PMID 10204489 DOI: 10.1016/S1074-7613(00)80033-3 |
0.423 |
|
| 1998 |
Shortman K, Vremec D, Corcoran LM, Georgopoulos K, Lucas K, Wu L. The linkage between T-cell and dendritic cell development in the mouse thymus. Immunological Reviews. 165: 39-46. PMID 9850850 DOI: 10.1111/J.1600-065X.1998.Tb01228.X |
0.431 |
|
| 1998 |
Wang JH, Avitahl N, Cariappa A, Friedrich C, Ikeda T, Renold A, Andrikopoulos K, Liang L, Pillai S, Morgan BA, Georgopoulos K. Aiolos regulates B cell activation and maturation to effector state Immunity. 9: 543-553. PMID 9806640 DOI: 10.1016/S1074-7613(00)80637-8 |
0.453 |
|
| 1998 |
Nichogiannopoulou A, Trevisan M, Friedrich C, Georgopoulos K. Ikaros in hemopoietic lineage determination and homeostasis Seminars in Immunology. 10: 119-125. PMID 9618757 DOI: 10.1006/Smim.1998.0113 |
0.471 |
|
| 1998 |
Kelley CM, Ikeda T, Koipally J, Avitahl N, Wu L, Georgopoulos K, Morgan BA. Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors. Current Biology : Cb. 8: 508-15. PMID 9560339 DOI: 10.1016/S0960-9822(98)70202-7 |
0.493 |
|
| 1997 |
Wu L, Nichogiannopoulou A, Shortman K, Georgopoulos K. Cell-Autonomous Defects in Dendritic Cell Populations of Ikaros Mutant Mice Point to a Developmental Relationship with the Lymphoid Lineage Immunity. 7: 483-492. PMID 9354469 DOI: 10.1016/S1074-7613(00)80370-2 |
0.423 |
|
| 1997 |
Morgan B, Sun L, Avitahl N, Andrikopoulos K, Ikeda T, Gonzales E, Wu P, Neben S, Georgopoulos K. Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation The Embo Journal. 16: 2004-2013. PMID 9155026 DOI: 10.1093/Emboj/16.8.2004 |
0.543 |
|
| 1997 |
Georgopoulos K, Winandy S, Avitahl N. The role of the Ikaros gene in lymphocyte development and homeostasis. Annual Review of Immunology. 15: 155-76. PMID 9143685 DOI: 10.1146/Annurev.Immunol.15.1.155 |
0.541 |
|
| 1997 |
Georgopoulos K. Transcription factors required for lymphoid lineage commitment Current Opinion in Immunology. 9: 222-227. PMID 9099800 DOI: 10.1016/S0952-7915(97)80139-2 |
0.501 |
|
| 1996 |
Wang JH, Nichogiannopoulou A, Wu L, Sun L, Sharpe AH, Bigby M, Georgopoulos K. Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation Immunity. 5: 537-549. PMID 8986714 DOI: 10.1016/S1074-7613(00)80269-1 |
0.439 |
|
| 1996 |
Sun L, Liu A, Georgopoulos K. Zinc finger-mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte development. The Embo Journal. 15: 5358-5369. DOI: 10.1002/J.1460-2075.1996.Tb00920.X |
0.411 |
|
| 1995 |
Winandy S, Wu P, Georgopoulos K. A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma. Cell. 83: 289-99. PMID 7585946 DOI: 10.1016/0092-8674(95)90170-1 |
0.476 |
|
| 1994 |
Molnár A, Georgopoulos K. The Ikaros gene encodes a family of functionally diverse zinc finger DNA-binding proteins. Molecular and Cellular Biology. 14: 8292-303. PMID 7969165 DOI: 10.1128/Mcb.14.12.8292 |
0.469 |
|
| 1994 |
Georgopoulos K, Bigby M, Wang JH, Molnar A, Wu P, Winandy S, Sharpe A. The Ikaros gene is required for the development of all lymphoid lineages. Cell. 79: 143-56. PMID 7923373 DOI: 10.1016/0092-8674(94)90407-3 |
0.511 |
|
| 1993 |
Clevers HC, Oosterwegel MA, Georgopoulos K. Transcription factors in early T-cell development. Immunology Today. 14: 591-6. PMID 7905739 DOI: 10.1016/0167-5699(93)90198-T |
0.513 |
|
| 1992 |
Georgopoulos K, Morgan BA, Moore DD. Functionally distinct isoforms of the CRE-BP DNA-binding protein mediate activity of a T-cell-specific enhancer Molecular and Cellular Biology. 12: 747-757. PMID 1531087 DOI: 10.1128/Mcb.12.2.747 |
0.491 |
|
| 1992 |
Georgopoulos K, Moore DD, Derfler B. Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment Science. 258: 808-812. PMID 1439790 DOI: 10.1126/Science.1439790 |
0.517 |
|
| 1991 |
Oosterwegel M, van de Wetering M, Dooijes D, Klomp L, Winoto A, Georgopoulos K, Meijlink F, Clevers H. Cloning of murine TCF-1, a T cell-specific transcription factor interacting with functional motifs in the CD3-epsilon and T cell receptor alpha enhancers. The Journal of Experimental Medicine. 173: 1133-42. PMID 1827138 DOI: 10.1084/Jem.173.5.1133 |
0.464 |
|
| 1990 |
Georgopoulos K, Galson D, Terhorst C. Tissue-specific nuclear factors mediate expression of the CD3 delta gene during T cell development. The Embo Journal. 9: 109-115. DOI: 10.1002/J.1460-2075.1990.Tb08086.X |
0.487 |
|
| 1989 |
Wilkinson MF, Georgopoulos K, Terhorst C, MacLeod CL. The CD3δ gene encodes multiple transcripts regulated by transcriptional and post-transcriptional mechanisms European Journal of Immunology. 19: 2355-2360. PMID 2532602 DOI: 10.1002/Eji.1830191226 |
0.482 |
|
| 1988 |
Halazonetis TD, Georgopoulos K, Greenberg ME, Leder P. c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities. Cell. 55: 917-24. PMID 3142692 DOI: 10.1016/0092-8674(88)90147-X |
0.327 |
|
| 1988 |
Clevers H, Dunlap S, Saito H, Georgopoulos K, Wileman T, Terhorst C. Characterization and expression of the murine CD3-epsilon gene. Proceedings of the National Academy of Sciences of the United States of America. 85: 8623-7. PMID 2973066 DOI: 10.1073/Pnas.85.22.8623 |
0.382 |
|
| 1988 |
Georgopoulos K, Elsen Pvd, Bier E, Maxam A, Terhorst C. A T cell-specific enhancer is located in a DNase I-hypersensitive area at the 3' end of the CD3-delta gene. The Embo Journal. 7: 2401-2407. DOI: 10.1002/J.1460-2075.1988.Tb03085.X |
0.463 |
|
| 1987 |
Saito H, Koyama T, Georgopoulos K, Clevers H, Haser WG, LeBien T, Tonegawa S, Terhorst C. Close linkage of the mouse and human CD3 gamma- and delta-chain genes suggests that their transcription is controlled by common regulatory elements. Proceedings of the National Academy of Sciences of the United States of America. 84: 9131-4. PMID 2827170 DOI: 10.1073/Pnas.84.24.9131 |
0.375 |
|
| 1986 |
van den Elsen P, Georgopoulos K, Shepley BA, Orkin S, Terhorst C. Exon/intron organization of the genes coding for the delta chains of the human and murine T-cell receptor/T3 complex. Proceedings of the National Academy of Sciences of the United States of America. 83: 2944-8. PMID 2939461 DOI: 10.1073/Pnas.83.9.2944 |
0.39 |
|
| 1986 |
Terhorst C, Vries Jd, Georgopoulos K, Gold D, Oettgen H, Pettey C, Spits H, Ucker D, Elsen Pvd, Wileman T. The T cell receptor/T3 complex. The Year in Immunology. 2: 245-253. DOI: 10.1007/978-1-4612-5014-2_7 |
0.383 |
|
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