Katia Georgopoulos - Publications

Harvard University, Cambridge, MA, United States 
Molecular Biology, Immunology, Biochemistry

96 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Kashiwagi M, Figueroa DS, Ay F, Morgan BA, Georgopoulos K. A double-negative thymocyte-specific enhancer augments Notch1 signaling to direct early T cell progenitor expansion, lineage restriction and β-selection. Nature Immunology. PMID 36316479 DOI: 10.1038/s41590-022-01322-y  0.409
2021 Lazarian G, Yin S, Ten Hacken E, Sewastianik T, Uduman M, Font-Tello A, Gohil SH, Li S, Kim E, Joyal H, Billington L, Witten E, Zheng M, Huang T, Severgnini M, ... ... Georgopoulos K, et al. A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation. Cancer Cell. 39: 380-393.e8. PMID 33689703 DOI: 10.1016/j.ccell.2021.02.003  0.336
2020 Shibata S, Kashiwagi M, Morgan BA, Georgopoulos K. Functional interactions between Mi-2β and AP1 complexes control response and recovery from skin barrier disruption. The Journal of Experimental Medicine. 217. PMID 31834931 DOI: 10.1084/Jem.20182402  0.329
2019 Yoshida T, Hu Y, Zhang Z, Emmanuel AO, Galani K, Muhire B, Snippert HJ, Williams CJ, Tolstorukov MY, Gounari F, Georgopoulos K. Chromatin restriction by the nucleosome remodeler Mi-2β and functional interplay with lineage-specific transcription regulators control B-cell differentiation. Genes & Development. PMID 31123064 DOI: 10.1101/Gad.321901.118  0.463
2019 Murthy V, Tebaldi T, Yoshida T, Erdin S, Calzonetti T, Vijayvargia R, Tripathi T, Kerschbamer E, Seong IS, Quattrone A, Talkowski ME, Gusella JF, Georgopoulos K, MacDonald ME, Biagioli M. Hypomorphic mutation of the mouse Huntington's disease gene orthologue. Plos Genetics. 15: e1007765. PMID 30897080 DOI: 10.1371/Journal.Pgen.1007765  0.348
2018 McClatchey AI, Georgopoulos K. Actin' Up to Stop SNFin Out TEAD. Developmental Cell. 47: 693-695. PMID 30562513 DOI: 10.1016/J.Devcel.2018.11.037  0.304
2018 Lazarian G, Yin S, Font-tello A, Ten Hacken E, Sevastianik T, Tom D, Regis FF, Gill A, Zheng M, Georgopoulos K, Neuberg DS, Wang L, Carrasco RD, Wu CJ. KZF-L162R Mutation Affects Splenic Mature B Cell Development and Alters Expression of Aiolos Target Genes Blood. 132: 668-668. DOI: 10.1182/Blood-2018-99-115483  0.463
2017 Hu Y, Yoshida T, Georgopoulos K. Transcriptional circuits in B cell transformation. Current Opinion in Hematology. PMID 28463873 DOI: 10.1097/Moh.0000000000000352  0.424
2017 Georgopoulos K. The making of a lymphocyte: the choice among disparate cell fates and the IKAROS enigma. Genes & Development. 31: 439-450. PMID 28385788 DOI: 10.1101/Gad.297002.117  0.473
2017 Georgopoulos K. In search of the mechanism that shapes the neutrophil's nucleus. Genes & Development. 31: 85-87. PMID 28202537 DOI: 10.1101/Gad.296228.117  0.35
2017 Kashiwagi M, Hosoi J, Lai JF, Brissette J, Ziegler SF, Morgan BA, Georgopoulos K. Direct control of regulatory T cells by keratinocytes. Nature Immunology. PMID 28092372 DOI: 10.1038/Ni.3661  0.386
2016 Hayakawa M, Hayakawa H, Petrova T, Ritprajak P, Sutavani RV, Jiménez-Andrade GY, Sano Y, Choo MK, Seavitt J, Venigalla RK, Otsu K, Georgopoulos K, Arthur JS, Park JM. Loss of functionally redundant p38 isoforms in T cells enhances regulatory T cell induction. The Journal of Biological Chemistry. PMID 28011639 DOI: 10.1074/Jbc.M116.764548  0.444
2016 Hu Y, Zhang Z, Kashiwagi M, Yoshida T, Joshi I, Jena N, Somasundaram R, Emmanuel AO, Sigvardsson M, Fitamant J, El-Bardeesy N, Gounari F, Van Etten RA, Georgopoulos K. Superenhancer reprogramming drives a B-cell-epithelial transition and high-risk leukemia. Genes & Development. 30: 1971-90. PMID 27664237 DOI: 10.1101/Gad.283762.116  0.503
2016 Georgopoulos K. Induction of Bcl11b during T cell commitment through a tripartite mechanism. Nature Immunology. 17: 903-4. PMID 27434004 DOI: 10.1038/Ni.3520  0.475
2016 Etten RV, Hu Y, Zhang Z, Yoshida T, Jena N, Kashiwagi M, Joshi I, El-Bardeesy N, Somasundaram R, Sigvardsson M, Liu Z, Tata P, Korber S, Raufi A, Krause D, ... ... Georgopoulos K, et al. Central role for ikaros in pre-B cell differentiation and pathogenesis of high-risk B-cell acute lymphoblastic leukemia Experimental Hematology. 44. DOI: 10.1016/J.Exphem.2016.06.024  0.37
2015 Perotti EA, Georgopoulos K, Yoshida T. An Ikaros Promoter Element with Dual Epigenetic and Transcriptional Activities. Plos One. 10: e0131568. PMID 26135129 DOI: 10.1371/Journal.Pone.0131568  0.419
2015 Georgopoulos K. Ebf1 in DNA repair and leukemogenesis. Blood. 125: 3969-71. PMID 26113531 DOI: 10.1182/Blood-2015-05-639427  0.48
2015 Jena N, Joshi I, Yoshida T, Zhang Z, Liu Z, Tata P, Shapiro IM, Pachter JA, Weaver DT, Georgopoulos K, Etten RAV. Abstract 4202: Targeting focal adhesion kinase is a novel approach to therapy of high-risk, Ikaros-mutant acute B-cell lymphoblastic leukemia Cancer Research. 75: 4202-4202. DOI: 10.1158/1538-7445.Am2015-4202  0.379
2014 Yoshida T, Georgopoulos K. Ikaros fingers on lymphocyte differentiation. International Journal of Hematology. 100: 220-9. PMID 25085254 DOI: 10.1007/S12185-014-1644-5  0.555
2014 Yamada T, Yang Y, Hemberg M, Yoshida T, Cho HY, Murphy JP, Fioravante D, Regehr WG, Gygi SP, Georgopoulos K, Bonni A. Promoter decommissioning by the NuRD chromatin remodeling complex triggers synaptic connectivity in the mammalian brain. Neuron. 83: 122-34. PMID 24991957 DOI: 10.1016/J.Neuron.2014.05.039  0.398
2014 Joshi I, Yoshida T, Jena N, Qi X, Zhang J, Van Etten RA, Georgopoulos K. Loss of Ikaros DNA-binding function confers integrin-dependent survival on pre-B cells and progression to acute lymphoblastic leukemia. Nature Immunology. 15: 294-304. PMID 24509510 DOI: 10.1038/Ni.2821  0.434
2014 Dose M, Emmanuel AO, Chaumeil J, Zhang J, Sun T, Germar K, Aghajani K, Davis EM, Keerthivasan S, Bredemeyer AL, Sleckman BP, Rosen ST, Skok JA, Le Beau MM, Georgopoulos K, et al. β-Catenin induces T-cell transformation by promoting genomic instability. Proceedings of the National Academy of Sciences of the United States of America. 111: 391-6. PMID 24371308 DOI: 10.1073/Pnas.1315752111  0.424
2014 Joshi I, Jena N, Yoshida T, Paraskevopoulou L, Zhang Z, Liu Z, Korber S, Krause DS, Shapiro IM, Weaver DT, Pachter JA, Paietta EM, Van Etten RA, Georgopoulos K. Focal Adhesion Kinase Inhibitors Reverse the Stromal Adhesion Phenotype of Ikaros-Mutant B-ALL, Induce Apopotosis, and Synergize with ABL1 Tyrosine Kinase Inhibitors: A New Paradigm for Pathogenesis and Therapy of High-Risk B-ALL Blood. 124: 285-285. DOI: 10.1182/Blood.V124.21.285.285  0.382
2013 Yoshida T, Georgopoulos K. GATA-3 controls self-renewal in stressed HSCs. Nature Immunology. 14: 1032-3. PMID 24048133 DOI: 10.1038/Ni.2715  0.365
2013 Yoshida T, Landhuis E, Dose M, Hazan I, Zhang J, Naito T, Jackson AF, Wu J, Perotti EA, Kaufmann C, Gounari F, Morgan BA, Georgopoulos K. Transcriptional regulation of the Ikzf1 locus. Blood. 122: 3149-59. PMID 24002445 DOI: 10.1182/Blood-2013-01-474916  0.733
2013 Jena N, Joshi I, Yoshida T, Qi X, Zhang J, Georgopoulos K, Etten RAV. Ikaros Mutation Confers Integrin-Dependent Survival Of Pre-B Cells and Progression To Acute Lymphoblastic Leukemia Blood. 122: 1259-1259. DOI: 10.1182/Blood.V122.21.1259.1259  0.441
2012 Quintana FJ, Jin H, Burns EJ, Nadeau M, Yeste A, Kumar D, Rangachari M, Zhu C, Xiao S, Seavitt J, Georgopoulos K, Kuchroo VK. Aiolos promotes TH17 differentiation by directly silencing Il2 expression. Nature Immunology. 13: 770-7. PMID 22751139 DOI: 10.1038/Ni.2363  0.396
2012 Han R, Beppu H, Lee YK, Georgopoulos K, Larue L, Li E, Weiner L, Brissette JL. A pair of transmembrane receptors essential for the retention and pigmentation of hair. Genesis (New York, N.Y. : 2000). 50: 783-800. PMID 22611050 DOI: 10.1002/Dvg.22039  0.358
2012 Martín-Ibáñez R, Crespo E, Esgleas M, Urban N, Wang B, Waclaw R, Georgopoulos K, Martínez S, Campbell K, Vicario-Abejón C, Alberch J, Chan S, Kastner P, Rubenstein JL, Canals JM. Helios transcription factor expression depends on Gsx2 and Dlx1&2 function in developing striatal matrix neurons. Stem Cells and Development. 21: 2239-51. PMID 22142223 DOI: 10.1089/Scd.2011.0607  0.386
2012 Zhang J, Jackson AF, Naito T, Dose M, Seavitt J, Liu F, Heller EJ, Kashiwagi M, Yoshida T, Gounari F, Petrie HT, Georgopoulos K. Harnessing of the nucleosome-remodeling-deacetylase complex controls lymphocyte development and prevents leukemogenesis. Nature Immunology. 13: 86-94. PMID 22080921 DOI: 10.1038/Ni.2150  0.472
2011 Harker N, Garefalaki A, Menzel U, Ktistaki E, Naito T, Georgopoulos K, Kioussis D. Pre-TCR signaling and CD8 gene bivalent chromatin resolution during thymocyte development. Journal of Immunology (Baltimore, Md. : 1950). 186: 6368-77. PMID 21515796 DOI: 10.4049/Jimmunol.1003567  0.342
2010 Gómez-del Arco P, Kashiwagi M, Jackson AF, Naito T, Zhang J, Liu F, Kee B, Vooijs M, Radtke F, Redondo JM, Georgopoulos K. Alternative promoter usage at the Notch1 locus supports ligand-independent signaling in T cell development and leukemogenesis. Immunity. 33: 685-98. PMID 21093322 DOI: 10.1016/J.Immuni.2010.11.008  0.502
2010 Yoshida T, Ng SY, Georgopoulos K. Awakening lineage potential by Ikaros-mediated transcriptional priming. Current Opinion in Immunology. 22: 154-60. PMID 20299195 DOI: 10.1016/J.Coi.2010.02.011  0.441
2010 Martín-Ibáñez R, Crespo E, Urbán N, Sergent-Tanguy S, Herranz C, Jaumot M, Valiente M, Long JE, Pineda JR, Andreu C, Rubenstein JL, Marín O, Georgopoulos K, Mengod G, Fariñas I, et al. Ikaros-1 couples cell cycle arrest of late striatal precursors with neurogenesis of enkephalinergic neurons. The Journal of Comparative Neurology. 518: 329-51. PMID 19950118 DOI: 10.1002/Cne.22215  0.316
2009 Mandal M, Powers SE, Ochiai K, Georgopoulos K, Kee BL, Singh H, Clark MR. Ras orchestrates exit from the cell cycle and light-chain recombination during early B cell development. Nature Immunology. 10: 1110-7. PMID 19734904 DOI: 10.1038/Ni.1785  0.426
2009 Ng SY, Yoshida T, Zhang J, Georgopoulos K. Genome-wide lineage-specific transcriptional networks underscore Ikaros-dependent lymphoid priming in hematopoietic stem cells. Immunity. 30: 493-507. PMID 19345118 DOI: 10.1016/J.Immuni.2009.01.014  0.483
2009 Georgopoulos K. From immunity to tolerance through HDAC. Nature Immunology. 10: 13-4. PMID 19088734 DOI: 10.1038/Ni0109-13  0.431
2008 Yoshida T, Hazan I, Zhang J, Ng SY, Naito T, Snippert HJ, Heller EJ, Qi X, Lawton LN, Williams CJ, Georgopoulos K. The role of the chromatin remodeler Mi-2beta in hematopoietic stem cell self-renewal and multilineage differentiation. Genes & Development. 22: 1174-89. PMID 18451107 DOI: 10.1101/Gad.1642808  0.435
2007 Naito T, Gómez-Del Arco P, Williams CJ, Georgopoulos K. Antagonistic interactions between Ikaros and the chromatin remodeler Mi-2beta determine silencer activity and Cd4 gene expression. Immunity. 27: 723-34. PMID 17980631 DOI: 10.1016/J.Immuni.2007.09.008  0.425
2007 Kioussis D, Georgopoulos K. Epigenetic flexibility underlying lineage choices in the adaptive immune system. Science (New York, N.Y.). 317: 620-2. PMID 17673651 DOI: 10.1126/Science.1143777  0.378
2007 Agoston DV, Szemes M, Dobi A, Palkovits M, Georgopoulos K, Gyorgy A, Ring MA. Ikaros is expressed in developing striatal neurons and involved in enkephalinergic differentiation. Journal of Neurochemistry. 102: 1805-16. PMID 17504264 DOI: 10.1111/J.1471-4159.2007.04653.X  0.443
2007 Thompson EC, Cobb BS, Sabbattini P, Meixlsperger S, Parelho V, Liberg D, Taylor B, Dillon N, Georgopoulos K, Jumaa H, Smale ST, Fisher AG, Merkenschlager M. Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits. Immunity. 26: 335-44. PMID 17363301 DOI: 10.1016/J.Immuni.2007.02.010  0.471
2007 Kashiwagi M, Morgan BA, Georgopoulos K. The chromatin remodeler Mi-2beta is required for establishment of the basal epidermis and normal differentiation of its progeny. Development (Cambridge, England). 134: 1571-82. PMID 17360773 DOI: 10.1242/Dev.001750  0.315
2007 Ng SY, Yoshida T, Georgopoulos K. Ikaros and chromatin regulation in early hematopoiesis. Current Opinion in Immunology. 19: 116-22. PMID 17307348 DOI: 10.1016/J.Coi.2007.02.014  0.422
2006 Yoshida T, Ng SY, Zuniga-Pflucker JC, Georgopoulos K. Early hematopoietic lineage restrictions directed by Ikaros. Nature Immunology. 7: 382-91. PMID 16518393 DOI: 10.1038/Ni1314  0.405
2006 Ueda Y, Okano M, Williams C, Chen T, Georgopoulos K, Li E. Roles for Dnmt3b in mammalian development: a mouse model for the ICF syndrome. Development (Cambridge, England). 133: 1183-92. PMID 16501171 DOI: 10.1242/Dev.02293  0.325
2005 Liu E, Sinha S, Williams C, Cyrille M, Heller E, Snapper SB, Georgopoulos K, St-Arnaud R, Force T, Dedhar S, Gerszten RE. Targeted deletion of integrin-linked kinase reveals a role in T-cell chemotaxis and survival. Molecular and Cellular Biology. 25: 11145-55. PMID 16314534 DOI: 10.1128/Mcb.25.24.11145-11155.2005  0.405
2005 Gómez-del Arco P, Koipally J, Georgopoulos K. Ikaros SUMOylation: switching out of repression. Molecular and Cellular Biology. 25: 2688-97. PMID 15767674 DOI: 10.1128/Mcb.25.7.2688-2697.2005  0.417
2004 Williams CJ, Naito T, Arco PG, Seavitt JR, Cashman SM, De Souza B, Qi X, Keables P, Von Andrian UH, Georgopoulos K. The chromatin remodeler Mi-2beta is required for CD4 expression and T cell development. Immunity. 20: 719-33. PMID 15189737 DOI: 10.1016/J.Immuni.2004.05.005  0.451
2004 Gómez-del Arco P, Maki K, Georgopoulos K. Phosphorylation controls Ikaros's ability to negatively regulate the G(1)-S transition. Molecular and Cellular Biology. 24: 2797-807. PMID 15024069 DOI: 10.1128/Mcb.24.7.2797-2807.2004  0.323
2004 Cortés M, Georgopoulos K. Aiolos is required for the generation of high affinity bone marrow plasma cells responsible for long-term immunity. The Journal of Experimental Medicine. 199: 209-19. PMID 14718515 DOI: 10.1084/Jem.20031571  0.34
2003 Kaufmann C, Yoshida T, Perotti EA, Landhuis E, Wu P, Georgopoulos K. A complex network of regulatory elements in Ikaros and their activity during hemo-lymphopoiesis. The Embo Journal. 22: 2211-23. PMID 12727887 DOI: 10.1093/Emboj/Cdg186  0.702
2003 Sun J, Matthias G, Mihatsch MJ, Georgopoulos K, Matthias P. Lack of the transcriptional coactivator OBF-1 prevents the development of systemic lupus erythematosus-like phenotypes in Aiolos mutant mice. Journal of Immunology (Baltimore, Md. : 1950). 170: 1699-706. PMID 12574333 DOI: 10.4049/Jimmunol.170.4.1699  0.433
2002 Harker N, Naito T, Cortes M, Hostert A, Hirschberg S, Tolaini M, Roderick K, Georgopoulos K, Kioussis D. The CD8alpha gene locus is regulated by the Ikaros family of proteins. Molecular Cell. 10: 1403-15. PMID 12504015 DOI: 10.1016/S1097-2765(02)00711-6  0.418
2002 Koipally J, Georgopoulos K. A molecular dissection of the repression circuitry of Ikaros. The Journal of Biological Chemistry. 277: 27697-705. PMID 12015313 DOI: 10.1074/Jbc.M201694200  0.368
2002 Koipally J, Georgopoulos K. Ikaros-CtIP interactions do not require C-terminal binding protein and participate in a deacetylase-independent mode of repression. The Journal of Biological Chemistry. 277: 23143-9. PMID 11959865 DOI: 10.1074/Jbc.M202079200  0.389
2002 Georgopoulos K. Haematopoietic cell-fate decisions, chromatin regulation and ikaros. Nature Reviews. Immunology. 2: 162-74. PMID 11913067 DOI: 10.1038/Nri747  0.446
2002 Koipally J, Heller EJ, Seavitt JR, Georgopoulos K. Unconventional potentiation of gene expression by Ikaros. The Journal of Biological Chemistry. 277: 13007-15. PMID 11799125 DOI: 10.1074/Jbc.M111371200  0.454
2002 DiFronzo NL, Leung CT, Mammel MK, Georgopoulos K, Taylor BJ, Pham QN. Ikaros, a lymphoid-cell-specific transcription factor, contributes to the leukemogenic phenotype of a mink cell focus-inducing murine leukemia virus. Journal of Virology. 76: 78-87. PMID 11739673 DOI: 10.1128/Jvi.76.1.78-87.2002  0.438
2001 Cariappa A, Tang M, Parng C, Nebelitskiy E, Carroll M, Georgopoulos K, Pillai S. The follicular versus marginal zone B lymphocyte cell fate decision is regulated by Aiolos, Btk, and CD21 Immunity. 14: 603-615. PMID 11371362 DOI: 10.1016/S1074-7613(01)00135-2  0.406
2001 Wu L, Vandenabeele S, Georgopoulos K. Derivation of dendritic cells from myeloid and lymphoid precursors. International Reviews of Immunology. 20: 117-135. PMID 11342301 DOI: 10.3109/08830180109056726  0.349
2001 Yamada A, Takaki S, Hayashi F, Georgopoulos K, Perlmutter RM, Takatsu K. Identification and characterization of a transcriptional regulator for the lck proximal promoter Journal of Biological Chemistry. 276: 18082-18089. PMID 11278409 DOI: 10.1074/Jbc.M008387200  0.507
2000 Koipally J, Georgopoulos K. Ikaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activity. Journal of Biological Chemistry. 275: 19594-19602. PMID 10766745 DOI: 10.1074/Jbc.M000254200  0.419
2000 Galy A, Christopherson I, Ferlazzo G, Liu G, Spits H, Georgopoulos K. Distinct signals control the hematopoiesis of lymphoid-related dendritic cells Blood. 95: 128-137. DOI: 10.1182/Blood.V95.1.128.001K06_128_137  0.323
1999 Koipally J, Kim J, Jones B, Jackson A, Avitahl N, Winandy S, Trevisan M, Nichogiannopoulou A, Kelley C, Georgopoulos K. Ikaros chromatin remodeling complexes in the control of differentiation of the hemo-lymphoid system Cold Spring Harbor Symposia On Quantitative Biology. 64: 79-86. PMID 11232340 DOI: 10.1101/Sqb.1999.64.79  0.33
1999 Nichogiannopoulou A, Trevisan M, Neben S, Friedrich C, Georgopoulos K. Defects in Hemopoietic Stem Cell Activity in Ikaros Mutant Mice Journal of Experimental Medicine. 190: 1201-1214. PMID 10544193 DOI: 10.1084/Jem.190.9.1201  0.399
1999 Winandy S, Wu L, Wang J, Georgopoulos K. Pre-T cell receptor (TCR) and TCR-controlled checkpoints in T cell differentiation are set by Ikaros. Journal of Experimental Medicine. 190: 1039-1048. PMID 10523602 DOI: 10.1084/Jem.190.8.1039  0.466
1999 Koipally J, Renold A, Kim J, Georgopoulos K. Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes Embo Journal. 18: 3090-3100. PMID 10357820 DOI: 10.1093/Emboj/18.11.3090  0.41
1999 Cortes M, Wong E, Koipally J, Georgopoulos K. Control of lymphocyte development by the Ikaros gene family. Current Opinion in Immunology. 11: 167-171. PMID 10322160 DOI: 10.1016/S0952-7915(99)80028-4  0.527
1999 Kim J, Sif S, Jones B, Jackson A, Koipally J, Heller E, Winandy S, Viel A, Sawyer A, Ikeda T, Kingston R, Georgopoulos K. Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes. Immunity. 10: 345-55. PMID 10204490 DOI: 10.1016/S1074-7613(00)80034-5  0.436
1999 Avitahl N, Winandy S, Friedrich C, Jones B, Ge Y, Georgopoulos K. Ikaros sets thresholds for T cell activation and regulates chromosome propagation. Immunity. 10: 333-43. PMID 10204489 DOI: 10.1016/S1074-7613(00)80033-3  0.423
1998 Shortman K, Vremec D, Corcoran LM, Georgopoulos K, Lucas K, Wu L. The linkage between T-cell and dendritic cell development in the mouse thymus. Immunological Reviews. 165: 39-46. PMID 9850850 DOI: 10.1111/J.1600-065X.1998.Tb01228.X  0.431
1998 Wang JH, Avitahl N, Cariappa A, Friedrich C, Ikeda T, Renold A, Andrikopoulos K, Liang L, Pillai S, Morgan BA, Georgopoulos K. Aiolos regulates B cell activation and maturation to effector state Immunity. 9: 543-553. PMID 9806640 DOI: 10.1016/S1074-7613(00)80637-8  0.453
1998 Nichogiannopoulou A, Trevisan M, Friedrich C, Georgopoulos K. Ikaros in hemopoietic lineage determination and homeostasis Seminars in Immunology. 10: 119-125. PMID 9618757 DOI: 10.1006/Smim.1998.0113  0.471
1998 Kelley CM, Ikeda T, Koipally J, Avitahl N, Wu L, Georgopoulos K, Morgan BA. Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors. Current Biology : Cb. 8: 508-15. PMID 9560339 DOI: 10.1016/S0960-9822(98)70202-7  0.493
1997 Wu L, Nichogiannopoulou A, Shortman K, Georgopoulos K. Cell-Autonomous Defects in Dendritic Cell Populations of Ikaros Mutant Mice Point to a Developmental Relationship with the Lymphoid Lineage Immunity. 7: 483-492. PMID 9354469 DOI: 10.1016/S1074-7613(00)80370-2  0.423
1997 Morgan B, Sun L, Avitahl N, Andrikopoulos K, Ikeda T, Gonzales E, Wu P, Neben S, Georgopoulos K. Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation The Embo Journal. 16: 2004-2013. PMID 9155026 DOI: 10.1093/Emboj/16.8.2004  0.543
1997 Georgopoulos K, Winandy S, Avitahl N. The role of the Ikaros gene in lymphocyte development and homeostasis. Annual Review of Immunology. 15: 155-76. PMID 9143685 DOI: 10.1146/Annurev.Immunol.15.1.155  0.541
1997 Georgopoulos K. Transcription factors required for lymphoid lineage commitment Current Opinion in Immunology. 9: 222-227. PMID 9099800 DOI: 10.1016/S0952-7915(97)80139-2  0.501
1996 Wang JH, Nichogiannopoulou A, Wu L, Sun L, Sharpe AH, Bigby M, Georgopoulos K. Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation Immunity. 5: 537-549. PMID 8986714 DOI: 10.1016/S1074-7613(00)80269-1  0.439
1996 Sun L, Liu A, Georgopoulos K. Zinc finger-mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte development. The Embo Journal. 15: 5358-5369. DOI: 10.1002/J.1460-2075.1996.Tb00920.X  0.411
1995 Winandy S, Wu P, Georgopoulos K. A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma. Cell. 83: 289-99. PMID 7585946 DOI: 10.1016/0092-8674(95)90170-1  0.476
1994 Molnár A, Georgopoulos K. The Ikaros gene encodes a family of functionally diverse zinc finger DNA-binding proteins. Molecular and Cellular Biology. 14: 8292-303. PMID 7969165 DOI: 10.1128/Mcb.14.12.8292  0.469
1994 Georgopoulos K, Bigby M, Wang JH, Molnar A, Wu P, Winandy S, Sharpe A. The Ikaros gene is required for the development of all lymphoid lineages. Cell. 79: 143-56. PMID 7923373 DOI: 10.1016/0092-8674(94)90407-3  0.511
1993 Clevers HC, Oosterwegel MA, Georgopoulos K. Transcription factors in early T-cell development. Immunology Today. 14: 591-6. PMID 7905739 DOI: 10.1016/0167-5699(93)90198-T  0.513
1992 Georgopoulos K, Morgan BA, Moore DD. Functionally distinct isoforms of the CRE-BP DNA-binding protein mediate activity of a T-cell-specific enhancer Molecular and Cellular Biology. 12: 747-757. PMID 1531087 DOI: 10.1128/Mcb.12.2.747  0.491
1992 Georgopoulos K, Moore DD, Derfler B. Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment Science. 258: 808-812. PMID 1439790 DOI: 10.1126/Science.1439790  0.517
1991 Oosterwegel M, van de Wetering M, Dooijes D, Klomp L, Winoto A, Georgopoulos K, Meijlink F, Clevers H. Cloning of murine TCF-1, a T cell-specific transcription factor interacting with functional motifs in the CD3-epsilon and T cell receptor alpha enhancers. The Journal of Experimental Medicine. 173: 1133-42. PMID 1827138 DOI: 10.1084/Jem.173.5.1133  0.464
1990 Georgopoulos K, Galson D, Terhorst C. Tissue-specific nuclear factors mediate expression of the CD3 delta gene during T cell development. The Embo Journal. 9: 109-115. DOI: 10.1002/J.1460-2075.1990.Tb08086.X  0.487
1989 Wilkinson MF, Georgopoulos K, Terhorst C, MacLeod CL. The CD3δ gene encodes multiple transcripts regulated by transcriptional and post-transcriptional mechanisms European Journal of Immunology. 19: 2355-2360. PMID 2532602 DOI: 10.1002/Eji.1830191226  0.482
1988 Halazonetis TD, Georgopoulos K, Greenberg ME, Leder P. c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities. Cell. 55: 917-24. PMID 3142692 DOI: 10.1016/0092-8674(88)90147-X  0.327
1988 Clevers H, Dunlap S, Saito H, Georgopoulos K, Wileman T, Terhorst C. Characterization and expression of the murine CD3-epsilon gene. Proceedings of the National Academy of Sciences of the United States of America. 85: 8623-7. PMID 2973066 DOI: 10.1073/Pnas.85.22.8623  0.382
1988 Georgopoulos K, Elsen Pvd, Bier E, Maxam A, Terhorst C. A T cell-specific enhancer is located in a DNase I-hypersensitive area at the 3' end of the CD3-delta gene. The Embo Journal. 7: 2401-2407. DOI: 10.1002/J.1460-2075.1988.Tb03085.X  0.463
1987 Saito H, Koyama T, Georgopoulos K, Clevers H, Haser WG, LeBien T, Tonegawa S, Terhorst C. Close linkage of the mouse and human CD3 gamma- and delta-chain genes suggests that their transcription is controlled by common regulatory elements. Proceedings of the National Academy of Sciences of the United States of America. 84: 9131-4. PMID 2827170 DOI: 10.1073/Pnas.84.24.9131  0.375
1986 van den Elsen P, Georgopoulos K, Shepley BA, Orkin S, Terhorst C. Exon/intron organization of the genes coding for the delta chains of the human and murine T-cell receptor/T3 complex. Proceedings of the National Academy of Sciences of the United States of America. 83: 2944-8. PMID 2939461 DOI: 10.1073/Pnas.83.9.2944  0.39
1986 Terhorst C, Vries Jd, Georgopoulos K, Gold D, Oettgen H, Pettey C, Spits H, Ucker D, Elsen Pvd, Wileman T. The T cell receptor/T3 complex. The Year in Immunology. 2: 245-253. DOI: 10.1007/978-1-4612-5014-2_7  0.383
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