Sidney W. Whiteheart - Publications

1994- Molecular and Cellular Biochemistry University of Kentucky, Lexington, KY 
Cell Biology, Biochemistry

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Pokrovskaya ID, Joshi S, Tobin M, Desai R, Aronova MA, Kamykowski JA, Zhang G, Whiteheart SW, Leapman RD, Storrie B. SNARE-dependent membrane fusion initiates α-granule matrix decondensation in mouse platelets. Blood Advances. 2: 2947-2958. PMID 30401752 DOI: 10.1182/bloodadvances.2018019158  0.32
2017 Batten SR, Matveeva EA, Whiteheart SW, Vanaman TC, Gerhardt GA, Slevin JT. Linking kindling to increased glutamate release in the dentate gyrus of the hippocampus through the STXBP5/tomosyn-1 gene. Brain and Behavior. 7: e00795. PMID 28948088 DOI: 10.1002/brb3.795  0.72
2016 Huang Y, Joshi S, Xiang B, Kanaho Y, Li Z, Bouchard BA, Moncman CL, Whiteheart SW. Arf6 controls platelet spreading and clot retraction via integrin αIIbβ3 trafficking. Blood. 127: 1459-67. PMID 26738539 DOI: 10.1182/blood-2015-05-648550  0.32
2016 Chicka MC, Ren Q, Richards D, Hellman LM, Zhang J, Fried MG, Whiteheart SW. Role of Munc13-4 as a Ca2+-dependent tether during platelet secretion. The Biochemical Journal. 473: 627-39. PMID 26637270 DOI: 10.1042/BJ20151150  1
2015 Xiang B, Zhang G, Ye S, Zhang R, Huang C, Liu J, Tao M, Ruan C, Smyth SS, Whiteheart SW, Li Z. Characterization of a Novel Integrin Binding Protein, VPS33B, Which Is Important for Platelet Activation and In Vivo Thrombosis and Hemostasis. Circulation. 132: 2334-44. PMID 26399659 DOI: 10.1161/CIRCULATIONAHA.115.018361  1
2015 Ouseph MM, Huang Y, Banerjee M, Joshi S, MacDonald L, Zhong Y, Liu H, Li X, Xiang B, Zhang G, Komatsu M, Komatsu M, Yue Z, Li Z, Storrie B, ... Whiteheart SW, et al. Autophagy is induced upon platelet activation and is essential for hemostasis and thrombosis. Blood. 126: 1224-33. PMID 26209658 DOI: 10.1182/blood-2014-09-598722  0.32
2014 Ye S, Huang Y, Joshi S, Zhang J, Yang F, Zhang G, Smyth SS, Li Z, Takai Y, Whiteheart SW. Platelet secretion and hemostasis require syntaxin-binding protein STXBP5. The Journal of Clinical Investigation. 124: 4517-28. PMID 25244094 DOI: 10.1172/JCI75572  1
2014 Jonnalagadda D, Sunkara M, Morris AJ, Whiteheart SW. Granule-mediated release of sphingosine-1-phosphate by activated platelets. Biochimica Et Biophysica Acta. 1841: 1581-9. PMID 25158625 DOI: 10.1016/j.bbalip.2014.08.013  0.32
2013 Xiang B, Zhang G, Guo L, Li XA, Morris AJ, Daugherty A, Whiteheart SW, Smyth SS, Li Z. Platelets protect from septic shock by inhibiting macrophage-dependent inflammation via the cyclooxygenase 1 signalling pathway. Nature Communications. 4: 2657. PMID 24150174 DOI: 10.1038/ncomms3657  0.32
2013 Karim ZA, Zhang J, Banerjee M, Chicka MC, Al Hawas R, Hamilton TR, Roche PA, Whiteheart SW. IκB kinase phosphorylation of SNAP-23 controls platelet secretion. Blood. 121: 4567-74. PMID 23613522 DOI: 10.1182/blood-2012-11-470468  0.64
2012 Xiang B, Zhang G, Stefanini L, Bergmeier W, Gartner TK, Whiteheart SW, Li Z. The Src family kinases and protein kinase C synergize to mediate Gq-dependent platelet activation. The Journal of Biological Chemistry. 287: 41277-87. PMID 23066026 DOI: 10.1074/jbc.M112.393124  0.32
2012 Al Hawas R, Ren Q, Ye S, Karim ZA, Filipovich AH, Whiteheart SW. Munc18b/STXBP2 is required for platelet secretion. Blood. 120: 2493-500. PMID 22791290 DOI: 10.1182/blood-2012-05-430629  1
2012 Ye S, Karim ZA, Al Hawas R, Pessin JE, Filipovich AH, Whiteheart SW. Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion. Blood. 120: 2484-92. PMID 22767500 DOI: 10.1182/blood-2012-05-430603  1
2012 Moeller A, Zhao C, Fried MG, Wilson-Kubalek EM, Carragher B, Whiteheart SW. Nucleotide-dependent conformational changes in the N-Ethylmaleimide Sensitive Factor (NSF) and their potential role in SNARE complex disassembly. Journal of Structural Biology. 177: 335-43. PMID 22245547 DOI: 10.1016/j.jsb.2011.12.018  0.72
2012 Matveeva EA, Davis VA, Whiteheart SW, Vanaman TC, Gerhardt GA, Slevin JT. Kindling-induced asymmetric accumulation of hippocampal 7S SNARE complexes correlates with enhanced glutamate release. Epilepsia. 53: 157-67. PMID 22150629 DOI: 10.1111/j.1528-1167.2011.03345.x  0.72
2012 Zhao C, Smith EC, Whiteheart SW. Requirements for the catalytic cycle of the N-ethylmaleimide-Sensitive Factor (NSF). Biochimica Et Biophysica Acta. 1823: 159-71. PMID 21689688 DOI: 10.1016/j.bbamcr.2011.06.003  0.72
2011 Zhang G, Xiang B, Ye S, Chrzanowska-Wodnicka M, Morris AJ, Gartner TK, Whiteheart SW, White GC, Smyth SS, Li Z. Distinct roles for Rap1b protein in platelet secretion and integrin αIIbβ3 outside-in signaling. The Journal of Biological Chemistry. 286: 39466-77. PMID 21940635 DOI: 10.1074/jbc.M111.239608  1
2011 Hellman LM, Zhao C, Melikishvili M, Tao X, Hopper JE, Whiteheart SW, Fried MG. Histidine-tag-directed chromophores for tracer analyses in the analytical ultracentrifuge. Methods (San Diego, Calif.). 54: 31-8. PMID 21187151 DOI: 10.1016/j.ymeth.2010.12.033  0.72
2010 Ren Q, Wimmer C, Chicka MC, Ye S, Ren Y, Hughson FM, Whiteheart SW. Munc13-4 is a limiting factor in the pathway required for platelet granule release and hemostasis. Blood. 116: 869-77. PMID 20435885 DOI: 10.1182/blood-2010-02-270934  1
2010 Choi W, Karim ZA, Whiteheart SW. Protein expression in platelets from six species that differ in their open canalicular system. Platelets. 21: 167-75. PMID 20196629 DOI: 10.3109/09537101003611385  0.64
2010 Zhao C, Hellman LM, Zhan X, Bowman WS, Whiteheart SW, Fried MG. Hexahistidine-tag-specific optical probes for analyses of proteins and their interactions. Analytical Biochemistry. 399: 237-45. PMID 20036207 DOI: 10.1016/j.ab.2009.12.028  0.72
2010 Kondkar AA, Bray MS, Leal SM, Nagalla S, Liu DJ, Jin Y, Dong JF, Ren Q, Whiteheart SW, Shaw C, Bray PF. VAMP8/endobrevin is overexpressed in hyperreactive human platelets: suggested role for platelet microRNA. Journal of Thrombosis and Haemostasis : Jth. 8: 369-78. PMID 19943878 DOI: 10.1111/j.1538-7836.2009.03700.x  1
2010 Zhao C, Matveeva EA, Ren Q, Whiteheart SW. Dissecting the N-ethylmaleimide-sensitive factor: required elements of the N and D1 domains. The Journal of Biological Chemistry. 285: 761-72. PMID 19887446 DOI: 10.1074/jbc.M109.056739  1
2009 Graham GJ, Ren Q, Dilks JR, Blair P, Whiteheart SW, Flaumenhaft R. Endobrevin/VAMP-8-dependent dense granule release mediates thrombus formation in vivo. Blood. 114: 1083-90. PMID 19395672 DOI: 10.1182/blood-2009-03-210211  1
2009 Konopatskaya O, Gilio K, Harper MT, Zhao Y, Cosemans JM, Karim ZA, Whiteheart SW, Molkentin JD, Verkade P, Watson SP, Heemskerk JW, Poole AW. PKCalpha regulates platelet granule secretion and thrombus formation in mice. The Journal of Clinical Investigation. 119: 399-407. PMID 19147982 DOI: 10.1172/JCI34665  0.64
2008 Ren Q, Ye S, Whiteheart SW. The platelet release reaction: just when you thought platelet secretion was simple. Current Opinion in Hematology. 15: 537-41. PMID 18695380 DOI: 10.1097/MOH.0b013e328309ec74  1
2008 Matveeva EA, Vanaman TC, Whiteheart SW, Slevin JT. Levetiracetam prevents kindling-induced asymmetric accumulation of hippocampal 7S SNARE complexes. Epilepsia. 49: 1749-58. PMID 18513349 DOI: 10.1111/j.1528-1167.2008.01687.x  0.72
2008 Crawford GL, Hart GW, Whiteheart SW. Murine platelets are not regulated by O-linked beta-N-acetylglucosamine. Archives of Biochemistry and Biophysics. 474: 220-4. PMID 18387355 DOI: 10.1016/  1
2008 Karim ZA, Choi W, Whiteheart SW. Primary platelet signaling cascades and integrin-mediated signaling control ADP-ribosylation factor (Arf) 6-GTP levels during platelet activation and aggregation. The Journal of Biological Chemistry. 283: 11995-2003. PMID 18326492 DOI: 10.1074/jbc.M800146200  0.64
2008 Smyth SS, Monroe DM, Wysokinski WE, McBane RD, Whiteheart SW, Becker RC, Steinhubl SR. Platelet activation and its patient-specific consequences. Thrombosis Research. 122: 435-41. PMID 17949794 DOI: 10.1016/j.thromres.2007.08.023  0.32
2007 Zhao C, Slevin JT, Whiteheart SW. Cellular functions of NSF: not just SNAPs and SNAREs. Febs Letters. 581: 2140-9. PMID 17397838 DOI: 10.1016/j.febslet.2007.03.032  0.72
2007 Matveeva EA, Vanaman TC, Whiteheart SW, Slevin JT. Asymmetric accumulation of hippocampal 7S SNARE complexes occurs regardless of kindling paradigm. Epilepsy Research. 73: 266-74. PMID 17174072 DOI: 10.1016/j.eplepsyres.2006.11.003  0.72
2007 Ren Q, Barber HK, Crawford GL, Karim ZA, Zhao C, Choi W, Wang CC, Hong W, Whiteheart SW. Endobrevin/VAMP-8 is the primary v-SNARE for the platelet release reaction. Molecular Biology of the Cell. 18: 24-33. PMID 17065550 DOI: 10.1091/mbc.E06-09-0785  1
2006 Choi W, Karim ZA, Whiteheart SW. Arf6 plays an early role in platelet activation by collagen and convulxin. Blood. 107: 3145-52. PMID 16352809 DOI: 10.1182/blood-2005-09-3563  0.64
2005 Hepp R, Puri N, Hohenstein AC, Crawford GL, Whiteheart SW, Roche PA. Phosphorylation of SNAP-23 regulates exocytosis from mast cells. The Journal of Biological Chemistry. 280: 6610-20. PMID 15611044 DOI: 10.1074/jbc.M412126200  1
2005 Gage RM, Matveeva EA, Whiteheart SW, von Zastrow M. Type I PDZ ligands are sufficient to promote rapid recycling of G Protein-coupled receptors independent of binding to N-ethylmaleimide-sensitive factor. The Journal of Biological Chemistry. 280: 3305-13. PMID 15548537 DOI: 10.1074/jbc.M406934200  0.72
2004 Schraw TD, Crawford GL, Ren Q, Choi W, Thurmond DC, Pessin J, Whiteheart SW. Platelets from Munc18c heterozygous mice exhibit normal stimulus-induced release. Thrombosis and Haemostasis. 92: 829-37. PMID 15467915 DOI: 10.1160/TH04-04-0263  1
2004 Rutledge TW, Whiteheart SW. Studies of secretion using permeabilized platelets. Methods in Molecular Biology (Clifton, N.J.). 272: 109-20. PMID 15226539 DOI: 10.1385/1-59259-782-3:109  1
2004 Whiteheart SW, Matveeva EA. Multiple binding proteins suggest diverse functions for the N-ethylmaleimide sensitive factor. Journal of Structural Biology. 146: 32-43. PMID 15037235 DOI: 10.1016/j.jsb.2003.09.015  0.72
2004 Dean WL, Whiteheart SW. Plasma membrane Ca(2+)-ATPase (PMCA) translocates to filopodia during platelet activation. Thrombosis and Haemostasis. 91: 325-33. PMID 14961161 DOI: 10.1160/TH03-07-0425  0.32
2003 Schraw TD, Lemons PP, Dean WL, Whiteheart SW. A role for Sec1/Munc18 proteins in platelet exocytosis. The Biochemical Journal. 374: 207-17. PMID 12773094 DOI: 10.1042/BJ20030610  0.68
2003 Schraw TD, Rutledge TW, Crawford GL, Bernstein AM, Kalen AL, Pessin JE, Whiteheart SW. Granule stores from cellubrevin/VAMP-3 null mouse platelets exhibit normal stimulus-induced release. Blood. 102: 1716-22. PMID 12738662 DOI: 10.1182/blood-2003-01-0331  1
2002 Rutledge TW, Whiteheart SW. SNAP-23 is a target for calpain cleavage in activated platelets. The Journal of Biological Chemistry. 277: 37009-15. PMID 12121992 DOI: 10.1074/jbc.M204526200  1
2002 Matveeva EA, May AP, He P, Whiteheart SW. Uncoupling the ATPase activity of the N-ethylmaleimide sensitive factor (NSF) from 20S complex disassembly. Biochemistry. 41: 530-6. PMID 11781091  0.72
1995 DeBello WM, O'Connor V, Dresbach T, Whiteheart SW, Wang SS, Schweizer FE, Betz H, Rothman JE, Augustine GJ. SNAP-mediated protein-protein interactions essential for neurotransmitter release. Nature. 373: 626-30. PMID 7854421 DOI: 10.1038/373626a0  1
1994 Whiteheart SW, Hart GW. Incorporation of [3H]ethanolamine into a single cytosolic protein in a cell free system: ethanolaminylation of EF-1 alpha in vitro. Archives of Biochemistry and Biophysics. 309: 387-91. PMID 8135552 DOI: 10.1006/abbi.1994.1128  1
1994 Whiteheart SW, Rossnagel K, Buhrow SA, Brunner M, Jaenicke R, Rothman JE. N-ethylmaleimide-sensitive fusion protein: a trimeric ATPase whose hydrolysis of ATP is required for membrane fusion. The Journal of Cell Biology. 126: 945-54. PMID 8051214 DOI: 10.1083/jcb.126.4.945  1
1993 Whiteheart SW, Griff IC, Brunner M, Clary DO, Mayer T, Buhrow SA, Rothman JE. SNAP family of NSF attachment proteins includes a brain-specific isoform. Nature. 362: 353-5. PMID 8455721 DOI: 10.1038/362353a0  1
1993 Söllner T, Whiteheart SW, Brunner M, Erdjument-Bromage H, Geromanos S, Tempst P, Rothman JE. SNAP receptors implicated in vesicle targeting and fusion Nature. 362: 318-324. PMID 8455717  1
1993 Söllner T, Bennett MK, Whiteheart SW, Scheller RH, Rothman JE. A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion. Cell. 75: 409-18. PMID 8221884 DOI: 10.1016/0092-8674(93)90376-2  1
1992 Whiteheart SW, Brunner M, Wilson DW, Wiedmann M, Rothman JE. Soluble N-ethylmaleimide-sensitive fusion attachment proteins (SNAPs) bind to a multi-SNAP receptor complex in Golgi membranes Journal of Biological Chemistry. 267: 12239-12243. PMID 1601890  1
1992 Wilson DW, Whiteheart SW, Wiedmann M, Brunner M, Rothman JE. A multisubunit particle implicated in membrane fusion Journal of Cell Biology. 117: 531-538. PMID 1315316  1
1991 Wilson DW, Whiteheart SW, Orci L, Rothman JE. Intracellular membrane fusion. Trends in Biochemical Sciences. 16: 334-7. PMID 1949154  1
1990 Whiteheart SW, McLenithan JC, Hart GW. Surfaces of murine lymphocyte subsets differ in sialylation states and antigen distribution of a major N-linked penultimate saccharide structure. Cellular Immunology. 125: 337-53. PMID 2137033  1
1989 Whiteheart SW, Shenbagamurthi P, Chen L, Cotter RJ, Hart GW. Murine elongation factor 1 alpha (EF-1 alpha) is posttranslationally modified by novel amide-linked ethanolamine-phosphoglycerol moieties. Addition of ethanolamine-phosphoglycerol to specific glutamic acid residues on EF-1 alpha. The Journal of Biological Chemistry. 264: 14334-41. PMID 2569467  1
1989 Whiteheart SW, Passaniti A, Reichner JS, Holt GD, Haltiwanger RS, Hart GW. Glycosyltransferase probes Methods in Enzymology. 179: 82-95. PMID 2516227 DOI: 10.1016/0076-6879(89)79116-3  1
1988 Reichner JS, Whiteheart SW, Hart GW. Intracellular trafficking of cell surface sialoglycoconjugates. The Journal of Biological Chemistry. 263: 16316-26. PMID 3182795  1
1987 Whiteheart SW, Hart GW. Sialyltransferases as specific cell surface probes of terminal and penultimate saccharide structures on living cells. Analytical Biochemistry. 163: 123-35. PMID 3304006  1
1987 Powell LD, Whiteheart SW, Hart GW. Cell surface sialic acid influences tumor cell recognition in the mixed lymphocyte reaction. Journal of Immunology (Baltimore, Md. : 1950). 139: 262-70. PMID 2953814  1
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