Nicholas K. Tonks - Publications

Stony Brook University, Stony Brook, NY, United States 
Molecular Biology, Biochemistry

41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Zhang J, Wang Z, Zhang S, Chen Y, Xiong X, Li X, Tonks NK, Fan G. Spatial regulation of signaling by the coordinated action of the protein tyrosine kinases MET and FER. Cellular Signalling. PMID 29920310 DOI: 10.1016/j.cellsig.2018.06.006  0.32
2018 Krishnan N, Bonham CA, Rus IA, Shrestha OK, Gauss CM, Haque A, Tocilj A, Joshua-Tor L, Tonks NK. Harnessing insulin- and leptin-induced oxidation of PTP1B for therapeutic development. Nature Communications. 9: 283. PMID 29348454 DOI: 10.1038/s41467-017-02252-2  1
2017 Zhang S, Fan G, Hao Y, Hammell M, Wilkinson JE, Tonks NK. Suppression of protein tyrosine phosphatase N23 predisposes to breast tumorigenesis via activation of FYN kinase. Genes & Development. PMID 29066500 DOI: 10.1101/gad.304261.117  0.32
2017 Gurung P, Fan G, Lukens JR, Vogel P, Tonks NK, Kanneganti TD. Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease. Immunity. PMID 28410990 DOI: 10.1016/j.immuni.2017.03.014  0.32
2016 Fan G, Zhang S, Gao Y, Greer PA, Tonks NK. HGF-independent regulation of MET and GAB1 by nonreceptor tyrosine kinase FER potentiates metastasis in ovarian cancer. Genes & Development. 30: 1542-57. PMID 27401557 DOI: 10.1101/gad.284166.116  0.32
2015 Boivin B, Tonks NK. PTP1B: mediating ROS signaling to silence genes. Molecular & Cellular Oncology. 2: e975633. PMID 27308433 DOI: 10.4161/23723556.2014.975633  0.4
2015 Krishnan N, Tonks NK. Anxious moments for the protein tyrosine phosphatase PTP1B. Trends in Neurosciences. 38: 462-5. PMID 26166619 DOI: 10.1016/j.tins.2015.06.006  0.4
2015 Fan G, Aleem S, Yang M, Miller WT, Tonks NK. Protein-tyrosine Phosphatase and Kinase Specificity in Regulation of SRC and Breast Tumor Kinase. The Journal of Biological Chemistry. 290: 15934-47. PMID 25897081 DOI: 10.1074/jbc.M115.651703  0.4
2015 Ramesh M, Krishnan N, Muthuswamy SK, Tonks NK. A novel phosphatidic acid-protein-tyrosine phosphatase D2 axis is essential for ERBB2 signaling in mammary epithelial cells. The Journal of Biological Chemistry. 290: 9646-59. PMID 25681440 DOI: 10.1074/jbc.M114.627968  0.4
2015 Fan G, Wrzeszczynski KO, Fu C, Su G, Pappin DJ, Lucito R, Tonks NK. A quantitative proteomics-based signature of platinum sensitivity in ovarian cancer cell lines. The Biochemical Journal. 465: 433-42. PMID 25406946 DOI: 10.1042/BJ20141087  0.44
2015 Chaudhary F, Lucito R, Tonks NK. Missing-in-Metastasis regulates cell motility and invasion via PTPδ-mediated changes in SRC activity. The Biochemical Journal. 465: 89-101. PMID 25287652 DOI: 10.1042/BJ20140573  0.44
2014 Yang M, Haase AD, Huang FK, Coulis G, Rivera KD, Dickinson BC, Chang CJ, Pappin DJ, Neubert TA, Hannon GJ, Boivin B, Tonks NK. Dephosphorylation of tyrosine 393 in argonaute 2 by protein tyrosine phosphatase 1B regulates gene silencing in oncogenic RAS-induced senescence. Molecular Cell. 55: 782-90. PMID 25175024 DOI: 10.1016/j.molcel.2014.07.018  0.4
2014 Pulido R, Baker SJ, Barata JT, Carracedo A, Cid VJ, Chin-Sang ID, Davé V, den Hertog J, Devreotes P, Eickholt BJ, Eng C, Furnari FB, Georgescu MM, Gericke A, Hopkins B, ... ... Tonks NK, et al. A unified nomenclature and amino acid numbering for human PTEN. Science Signaling. 7: pe15. PMID 24985344 DOI: 10.1126/scisignal.2005560  0.4
2014 Schwertassek U, Haque A, Krishnan N, Greiner R, Weingarten L, Dick TP, Tonks NK. Reactivation of oxidized PTP1B and PTEN by thioredoxin 1. The Febs Journal. 281: 3545-58. PMID 24976139 DOI: 10.1111/febs.12898  0.4
2014 Krishnan N, Koveal D, Miller DH, Xue B, Akshinthala SD, Kragelj J, Jensen MR, Gauss CM, Page R, Blackledge M, Muthuswamy SK, Peti W, Tonks NK. Targeting the disordered C terminus of PTP1B with an allosteric inhibitor. Nature Chemical Biology. 10: 558-66. PMID 24845231 DOI: 10.1038/nchembio.1528  0.4
2013 Boivin B, Chaudhary F, Dickinson BC, Haque A, Pero SC, Chang CJ, Tonks NK. Receptor protein-tyrosine phosphatase α regulates focal adhesion kinase phosphorylation and ErbB2 oncoprotein-mediated mammary epithelial cell motility. The Journal of Biological Chemistry. 288: 36926-35. PMID 24217252 DOI: 10.1074/jbc.M113.527564  0.4
2013 Dagnell M, Frijhoff J, Pader I, Augsten M, Boivin B, Xu J, Mandal PK, Tonks NK, Hellberg C, Conrad M, Arnér ES, Östman A. Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-β receptor tyrosine kinase signaling. Proceedings of the National Academy of Sciences of the United States of America. 110: 13398-403. PMID 23901112 DOI: 10.1073/pnas.1302891110  0.4
2013 Fan G, Lin G, Lucito R, Tonks NK. Protein-tyrosine phosphatase 1B antagonized signaling by insulin-like growth factor-1 receptor and kinase BRK/PTK6 in ovarian cancer cells. The Journal of Biological Chemistry. 288: 24923-34. PMID 23814047 DOI: 10.1074/jbc.M113.482737  0.44
2013 Krishnan N, Bencze G, Cohen P, Tonks NK. The anti-inflammatory compound BAY-11-7082 is a potent inhibitor of protein tyrosine phosphatases. The Febs Journal. 280: 2830-41. PMID 23578302 DOI: 10.1111/febs.12283  0.4
2012 Haque A, Tonks NK. The use of phage display to generate conformation-sensor recombinant antibodies. Nature Protocols. 7: 2127-43. PMID 23154784 DOI: 10.1038/nprot.2012.132  1
2012 Zhang XC, Piccini A, Myers MP, Van Aelst L, Tonks NK. Functional analysis of the protein phosphatase activity of PTEN. The Biochemical Journal. 444: 457-64. PMID 22413754 DOI: 10.1042/BJ20120098  0.4
2011 Haque A, Andersen JN, Salmeen A, Barford D, Tonks NK. Conformation-sensing antibodies stabilize the oxidized form of PTP1B and inhibit its phosphatase activity. Cell. 147: 185-98. PMID 21962515 DOI: 10.1016/j.cell.2011.08.036  1
2011 Hyun SW, Anglin IE, Liu A, Yang S, Sorkin JD, Lillehoj E, Tonks NK, Passaniti A, Goldblum SE. Diverse injurious stimuli reduce protein tyrosine phosphatase-μ expression and enhance epidermal growth factor receptor signaling in human airway epithelia. Experimental Lung Research. 37: 327-43. PMID 21649524 DOI: 10.3109/01902148.2011.566673  0.4
2010 Boivin B, Yang M, Tonks NK. Targeting the reversibly oxidized protein tyrosine phosphatase superfamily. Science Signaling. 3: pl2. PMID 20807953 DOI: 10.1126/scisignal.3137pl2  0.4
2010 Boivin B, Tonks NK. Analysis of the redox regulation of protein tyrosine phosphatase superfamily members utilizing a cysteinyl-labeling assay. Methods in Enzymology. 474: 35-50. PMID 20609903 DOI: 10.1016/S0076-6879(10)74003-9  0.4
2010 Schwertassek U, Buckley DA, Xu CF, Lindsay AJ, McCaffrey MW, Neubert TA, Tonks NK. Myristoylation of the dual-specificity phosphatase c-JUN N-terminal kinase (JNK) stimulatory phosphatase 1 is necessary for its activation of JNK signaling and apoptosis. The Febs Journal. 277: 2463-73. PMID 20553486 DOI: 10.1111/j.1742-4658.2010.07661.x  0.4
2010 Hinton SD, Myers MP, Roggero VR, Allison LA, Tonks NK. The pseudophosphatase MK-STYX interacts with G3BP and decreases stress granule formation. The Biochemical Journal. 427: 349-57. PMID 20180778 DOI: 10.1042/BJ20091383  0.4
2009 Loh K, Deng H, Fukushima A, Cai X, Boivin B, Galic S, Bruce C, Shields BJ, Skiba B, Ooms LM, Stepto N, Wu B, Mitchell CA, Tonks NK, Watt MJ, et al. Reactive oxygen species enhance insulin sensitivity. Cell Metabolism. 10: 260-72. PMID 19808019 DOI: 10.1016/j.cmet.2009.08.009  0.4
2009 Krishnan N, Jeong DG, Jung SK, Ryu SE, Xiao A, Allis CD, Kim SJ, Tonks NK. Dephosphorylation of the C-terminal tyrosyl residue of the DNA damage-related histone H2A.X is mediated by the protein phosphatase eyes absent. The Journal of Biological Chemistry. 284: 16066-70. PMID 19351884 DOI: 10.1074/jbc.C900032200  0.4
2008 Boivin B, Zhang S, Arbiser JL, Zhang ZY, Tonks NK. A modified cysteinyl-labeling assay reveals reversible oxidation of protein tyrosine phosphatases in angiomyolipoma cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 9959-64. PMID 18632564 DOI: 10.1073/pnas.0804336105  0.4
2008 Juarez JC, Manuia M, Burnett ME, Betancourt O, Boivin B, Shaw DE, Tonks NK, Mazar AP, Doñate F. Superoxide dismutase 1 (SOD1) is essential for H2O2-mediated oxidation and inactivation of phosphatases in growth factor signaling. Proceedings of the National Academy of Sciences of the United States of America. 105: 7147-52. PMID 18480265 DOI: 10.1073/pnas.0709451105  0.4
2006 Nelson KK, Subbaram S, Connor KM, Dasgupta J, Ha XF, Meng TC, Tonks NK, Melendez JA. Redox-dependent matrix metalloproteinase-1 expression is regulated by JNK through Ets and AP-1 promoter motifs. The Journal of Biological Chemistry. 281: 14100-10. PMID 16569638 DOI: 10.1074/jbc.M601820200  0.4
2005 Sui XF, Kiser TD, Hyun SW, Angelini DJ, Del Vecchio RL, Young BA, Hasday JD, Romer LH, Passaniti A, Tonks NK, Goldblum SE. Receptor protein tyrosine phosphatase micro regulates the paracellular pathway in human lung microvascular endothelia. The American Journal of Pathology. 166: 1247-58. PMID 15793303  0.4
2005 Galic S, Hauser C, Kahn BB, Haj FG, Neel BG, Tonks NK, Tiganis T. Coordinated regulation of insulin signaling by the protein tyrosine phosphatases PTP1B and TCPTP Molecular and Cellular Biology. 25: 819-829. PMID 15632081 DOI: 10.1128/MCB.25.2.819-829.2005  0.4
2005 Del Vecchio RL, Tonks NK. The conserved immunoglobulin domain controls the subcellular localization of the homophilic adhesion receptor protein-tyrosine phosphatase mu. The Journal of Biological Chemistry. 280: 1603-12. PMID 15491993 DOI: 10.1074/jbc.M410181200  0.4
2004 Chen HH, Luche R, Wei B, Tonks NK. Characterization of two distinct dual specificity phosphatases encoded in alternative open reading frames of a single gene located on human chromosome 10q22.2. The Journal of Biological Chemistry. 279: 41404-13. PMID 15252030 DOI: 10.1074/jbc.M405286200  0.48
2004 Andersen JN, Jansen PG, Echwald SM, Mortensen OH, Fukada T, Del Vecchio R, Tonks NK, Møller NP. A genomic perspective on protein tyrosine phosphatases: gene structure, pseudogenes, and genetic disease linkage. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 8-30. PMID 14718383 DOI: 10.1096/fj.02-1212rev  0.4
2003 Salmeen A, Andersen JN, Myers MP, Meng TC, Hinks JA, Tonks NK, Barford D. Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate. Nature. 423: 769-73. PMID 12802338 DOI: 10.1038/nature01680  0.4
2003 Torres J, Rodriguez J, Myers MP, Valiente M, Graves JD, Tonks NK, Pulido R. Phosphorylation-regulated cleavage of the tumor suppressor PTEN by caspase-3: implications for the control of protein stability and PTEN-protein interactions. The Journal of Biological Chemistry. 278: 30652-60. PMID 12788938 DOI: 10.1074/jbc.M212610200  0.4
2003 Palka HL, Park M, Tonks NK. Hepatocyte growth factor receptor tyrosine kinase met is a substrate of the receptor protein-tyrosine phosphatase DEP-1. The Journal of Biological Chemistry. 278: 5728-35. PMID 12475979 DOI: 10.1074/jbc.M210656200  0.4
2002 Harrington RJ, Gutch MJ, Hengartner MO, Tonks NK, Chisholm AD. The C. elegans LAR-like receptor tyrosine phosphatase PTP-3 and the VAB-1 Eph receptor tyrosine kinase have partly redundant functions in morphogenesis. Development (Cambridge, England). 129: 2141-53. PMID 11959824  0.4
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