Mitchell Lewis - Publications

University of Pennsylvania, Philadelphia, PA, United States 

41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Sochor MA, Vasireddy V, Drivas TG, Wojno A, Doung T, Shpylchak I, Bennicelli J, Chung D, Bennett J, Lewis M. An Autogenously Regulated Expression System for Gene Therapeutic Ocular Applications. Scientific Reports. 5: 17105. PMID 26597678 DOI: 10.1038/Srep17105  0.4
2011 Daber R, Sochor MA, Lewis M. Thermodynamic analysis of mutant lac repressors. Journal of Molecular Biology. 409: 76-87. PMID 21459098 DOI: 10.1016/J.Jmb.2011.03.057  0.4
2010 Milk L, Daber R, Lewis M. Functional rules for lac repressor-operator associations and implications for protein-DNA interactions. Protein Science : a Publication of the Protein Society. 19: 1162-72. PMID 20512969 DOI: 10.1002/Pro.389  0.4
2009 Daber R, Lewis M. Towards evolving a better repressor. Protein Engineering, Design & Selection : Peds. 22: 673-83. PMID 19729374 DOI: 10.1093/Protein/Gzp051  0.4
2009 Daber R, Sharp K, Lewis M. One is not enough. Journal of Molecular Biology. 392: 1133-44. PMID 19631220 DOI: 10.1016/J.Jmb.2009.07.050  0.4
2009 Daber R, Lewis M. A novel molecular switch. Journal of Molecular Biology. 391: 661-70. PMID 19540845 DOI: 10.1016/J.Jmb.2009.06.039  0.4
2009 Hochschild A, Lewis M. The bacteriophage lambda CI protein finds an asymmetric solution. Current Opinion in Structural Biology. 19: 79-86. PMID 19181516 DOI: 10.1016/J.Sbi.2008.12.008  0.4
2008 Stayrook S, Jaru-Ampornpan P, Ni J, Hochschild A, Lewis M. Crystal structure of the lambda repressor and a model for pairwise cooperative operator binding. Nature. 452: 1022-5. PMID 18432246 DOI: 10.1038/Nature06831  0.4
2007 Daber R, Stayrook S, Rosenberg A, Lewis M. Structural analysis of lac repressor bound to allosteric effectors. Journal of Molecular Biology. 370: 609-19. PMID 17543986 DOI: 10.1016/J.Jmb.2007.04.028  0.4
2006 Pinkett HW, Shearwin KE, Stayrook S, Dodd IB, Burr T, Hochschild A, Egan JB, Lewis M. The structural basis of cooperative regulation at an alternate genetic switch Molecular Cell. 21: 605-615. PMID 16507359 DOI: 10.1016/J.Molcel.2006.01.019  0.4
2004 Huang SS, Koder RL, Lewis M, Wand AJ, Dutton PL. The HP-1 maquette: from an apoprotein structure to a structured hemoprotein designed to promote redox-coupled proton exchange. Proceedings of the National Academy of Sciences of the United States of America. 101: 5536-41. PMID 15056758 DOI: 10.1073/Pnas.0306676101  0.4
2003 Penning TM, Jin Y, Heredia VV, Lewis M. Structure-function relationships in 3alpha-hydroxysteroid dehydrogenases: a comparison of the rat and human isoforms. The Journal of Steroid Biochemistry and Molecular Biology. 85: 247-55. PMID 12943710 DOI: 10.1016/S0960-0760(03)00236-X  0.4
2003 Huang SS, Gibney BR, Stayrook SE, Leslie Dutton P, Lewis M. X-ray structure of a maquette scaffold. Journal of Molecular Biology. 326: 1219-25. PMID 12589764 DOI: 10.1016/S0022-2836(02)01441-9  0.4
2001 Bell CE, Lewis M. Crystal structure of the lambda repressor C-terminal domain octamer. Journal of Molecular Biology. 314: 1127-36. PMID 11743728 DOI: 10.1006/Jmbi.2000.5196  0.4
2001 Bell CE, Barry J, Matthews KS, Lewis M. Structure of a variant of lac repressor with increased thermostability and decreased affinity for operator. Journal of Molecular Biology. 313: 99-109. PMID 11601849 DOI: 10.1006/Jmbi.2001.5041  0.4
2001 Bell CE, Lewis M. Crystallographic analysis of Lac repressor bound to natural operator O1. Journal of Molecular Biology. 312: 921-6. PMID 11580238 DOI: 10.1006/Jmbi.2001.5024  0.4
2001 Jin Y, Stayrook SE, Albert RH, Palackal NT, Penning TM, Lewis M. Crystal structure of human type III 3alpha-hydroxysteroid dehydrogenase/bile acid binding protein complexed with NADP(+) and ursodeoxycholate. Biochemistry. 40: 10161-8. PMID 11513593 DOI: 10.2210/Pdb1Ihi/Pdb  0.4
2001 Bell CE, Lewis M. The Lac repressor: a second generation of structural and functional studies. Current Opinion in Structural Biology. 11: 19-25. PMID 11179887 DOI: 10.1016/S0959-440X(00)00180-9  0.4
2000 Bell CE, Frescura P, Hochschild A, Lewis M. Crystal structure of the lambda repressor C-terminal domain provides a model for cooperative operator binding. Cell. 101: 801-11. PMID 10892750 DOI: 10.1016/S0092-8674(00)80891-0  0.4
2000 Bell CE, Lewis M. A closer view of the conformation of the Lac repressor bound to operator. Nature Structural Biology. 7: 209-14. PMID 10700279 DOI: 10.1038/73317  0.4
1999 Summa CM, Lombardi A, Lewis M, DeGrado WF. Tertiary templates for the design of diiron proteins. Current Opinion in Structural Biology. 9: 500-8. PMID 10449377 DOI: 10.1016/S0959-440X(99)80071-2  0.4
1999 Summa CM, Lombardi A, Lewis M, DeGrado WF. Corrigendum: Tertiary templates for the design of diiron proteins (Current Opinion in Structural Biology (1999) 9 (500-508)) Current Opinion in Structural Biology. 9: 649. DOI: 10.1016/S0959-440X(99)00021-4  0.4
1998 Arakane F, Kallen CB, Watari H, Stayrook SE, Lewis M, Strauss JF. Steroidogenic acute regulatory protein (StAR) acts on the outside of mitochondria to stimulate steroidogenesis. Endocrine Research. 24: 463-8. PMID 9888526 DOI: 10.3109/07435809809032634  0.36
1998 Kallen CB, Billheimer JT, Summers SA, Stayrook SE, Lewis M, Strauss JF. Steroidogenic acute regulatory protein (StAR) is a sterol transfer protein. The Journal of Biological Chemistry. 273: 26285-8. PMID 9756854 DOI: 10.1074/jbc.273.41.26285  0.4
1998 Arakane F, Kallen CB, Watari H, Foster JA, Sepuri NB, Pain D, Stayrook SE, Lewis M, Gerton GL, Strauss JF. The mechanism of action of steroidogenic acute regulatory protein (StAR). StAR acts on the outside of mitochondria to stimulate steroidogenesis. The Journal of Biological Chemistry. 273: 16339-45. PMID 9632696 DOI: 10.1074/Jbc.273.26.16339  0.36
1997 Pace HC, Kercher MA, Lu P, Markiewicz P, Miller JH, Chang G, Lewis M. Lac repressor genetic map in real space Trends in Biochemical Sciences. 22: 334-339. PMID 9301333 DOI: 10.1016/S0968-0004(97)01104-3  0.4
1997 Kercher MA, Lu P, Lewis M. Lac repressor-operator complex Current Opinion in Structural Biology. 7: 76-85. PMID 9032054 DOI: 10.1016/S0959-440X(97)80010-3  0.4
1997 Penning TM, Bennett MJ, Smith-Hoog S, Schlegel BP, Jez JM, Lewis M. Structure and function of 3 alpha-hydroxysteroid dehydrogenase. Steroids. 62: 101-11. PMID 9029723 DOI: 10.1016/S0039-128X(96)00167-5  0.4
1997 Horton N, Lewis M, Lu P. Escherichia coli lac repressor-lac operator interaction and the influence of allosteric effectors Journal of Molecular Biology. 265: 1-7. PMID 8995519 DOI: 10.1006/Jmbi.1996.0706  0.4
1996 Perros M, Steitz TA. DNA looping and lac repressor-CAP interaction. Science (New York, N.Y.). 274: 1929-30; author repl. PMID 8984647 DOI: 10.1126/Science.274.5294.1929  0.4
1996 Penning TM, Pawlowski JE, Schlegel BP, Jez JM, Lin HK, Hoog SS, Bennett MJ, Lewis M. Mammalian 3 alpha-hydroxysteroid dehydrogenases. Steroids. 61: 508-23. PMID 8883217 DOI: 10.1016/S0039-128X(96)00093-1  0.4
1996 Lewis M, Chang G, Horton NC, Kercher MA, Pace HC, Schumacher MA, Brennan RG, Lu P. Crystal structure of the lactose operon represser and its complexes with DNA and inducer Science. 271: 1247-1254. PMID 8638105 DOI: 10.1126/Science.271.5253.1247  0.4
1990 Pace HC, Lu P, Lewis M. lac Repressor: Crystallization of intact tetramer and its complexes with inducer and operator DNA Proceedings of the National Academy of Sciences of the United States of America. 87: 1870-1873. PMID 2408042 DOI: 10.1073/Pnas.87.5.1870  0.4
1989 Acharya KR, Stuart DI, Walker NP, Lewis M, Phillips DC. Refined structure of baboon alpha-lactalbumin at 1.7 A resolution. Comparison with C-type lysozyme. Journal of Molecular Biology. 208: 99-127. PMID 2769757 DOI: 10.1016/0022-2836(89)90091-0  0.4
1986 Stuart DI, Acharya KR, Walker NP, Smith SG, Lewis M, Phillips DC. Alpha-lactalbumin possesses a novel calcium binding loop. Nature. 324: 84-7. PMID 3785375 DOI: 10.1038/324084A0  0.4
1983 Rees DC, Lewis M, Lipscomb WN. Refined crystal structure of carboxypeptidase A at 1.54 A resolution. Journal of Molecular Biology. 168: 367-87. PMID 6887246 DOI: 10.1016/S0022-2836(83)80024-2  0.4
1983 Ohlendorf DH, Anderson WF, Lewis M, Pabo CO, Matthews BW. Comparison of the structures of cro and lambda repressor proteins from bacteriophage lambda. Journal of Molecular Biology. 169: 757-69. PMID 6226802 DOI: 10.2210/Pdb1Lrp/Pdb  0.4
1982 Pabo CO, Lewis M. The operator-binding domain of lambda repressor: structure and DNA recognition. Nature. 298: 443-7. PMID 7088190 DOI: 10.1038/298443a0  0.4
1982 Sauer RT, Yocum RR, Doolittle RF, Lewis M, Pabo CO. Homology among DNA-binding proteins suggests use of a conserved super-secondary structure. Nature. 298: 447-51. PMID 6896364 DOI: 10.1038/298447A0  0.4
1981 Rees DC, Lewis M, Honzatko RB, Lipscomb WN, Hardman KD. Zinc environment and cis peptide bonds in carboxypeptidase A at 1.75-A resolution. Proceedings of the National Academy of Sciences of the United States of America. 78: 3408-12. PMID 6943549 DOI: 10.1073/Pnas.78.6.3408  0.4
1979 Aschaffenburg R, Lewis M, Phillips DC, Press EM, Smith SG, Sutton BJ, Mountford CW. Crystallographic studies of immunoglobulins: crystallization of the Fc fragment of rabbit IgG with and without cleavage of the inter-chain disulphide bridge. Journal of Molecular Biology. 135: 1033-6. PMID 537094 DOI: 10.1016/0022-2836(79)90528-X  0.4
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