Thomas E. Smithgall - Publications

Affiliations: 
University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Molecular Biology, Oncology, Biochemistry

79 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Weir MC, Shu ST, Patel RK, Hellwig S, Chen L, Tan L, Gray NS, Smithgall TE. Selective inhibition of the myeloid Src-family kinase Fgr potently suppresses AML cell growth in vitro and in vivo. Acs Chemical Biology. PMID 29763550 DOI: 10.1021/acschembio.8b00154  0.44
2017 Weir MC, Hellwig S, Tan L, Liu Y, Gray NS, Smithgall TE. Dual inhibition of Fes and Flt3 tyrosine kinases potently inhibits Flt3-ITD+ AML cell growth. Plos One. 12: e0181178. PMID 28727840 DOI: 10.1371/journal.pone.0181178  0.44
2017 Tan R, Nakajima S, Wang Q, Sun H, Xue J, Wu J, Hellwig S, Zeng X, Yates NA, Smithgall TE, Lei M, Jiang Y, Levine AS, Su B, Lan L. Nek7 Protects Telomeres from Oxidative DNA Damage by Phosphorylation and Stabilization of TRF1. Molecular Cell. PMID 28216227 DOI: 10.1016/j.molcel.2017.01.015  0.44
2016 Wales TE, Poe JA, Emert-Sedlak L, Morgan CR, Smithgall TE, Engen JR. Hydrogen Exchange Mass Spectrometry of Related Proteins with Divergent Sequences: A Comparative Study of HIV-1 Nef Allelic Variants. Journal of the American Society For Mass Spectrometry. PMID 27032648 DOI: 10.1007/s13361-016-1365-5  0.84
2016 Emert-Sedlak LA, Loughran HM, Shi H, Kulp JL, Shu ST, Zhao J, Day BW, Wrobel JE, Reitz AB, Smithgall TE. Synthesis and evaluation of orally active small molecule HIV-1 Nef antagonists. Bioorganic & Medicinal Chemistry Letters. 26: 1480-4. PMID 26852364 DOI: 10.1016/j.bmcl.2016.01.043  0.56
2016 Roberts JM, Tarafdar S, Joseph RE, Andreotti AH, Smithgall TE, Engen JR, Wales TE. Dynamics of the Tec-family Tyrosine Kinase SH3 domains. Protein Science : a Publication of the Protein Society. PMID 26808198 DOI: 10.1002/pro.2887  0.56
2015 Grover P, Shi H, Baumgartner M, Camacho CJ, Smithgall TE. Fluorescence Polarization Screening Assays for Small Molecule Allosteric Modulators of ABL Kinase Function. Plos One. 10: e0133590. PMID 26222440 DOI: 10.1371/journal.pone.0133590  0.56
2015 Pirrone GF, Emert-Sedlak LA, Wales TE, Smithgall TE, Kent MS, Engen JR. Membrane-Associated Conformation of HIV-1 Nef Investigated with Hydrogen Exchange Mass Spectrometry at a Langmuir Monolayer. Analytical Chemistry. PMID 26133569 DOI: 10.1021/acs.analchem.5b01725  0.56
2015 Moroco JA, Baumgartner MP, Rust HL, Choi HG, Hur W, Gray NS, Camacho CJ, Smithgall TE. A Discovery Strategy for Selective Inhibitors of c-Src in Complex with the Focal Adhesion Kinase SH3/SH2-binding Region. Chemical Biology & Drug Design. 86: 144-55. PMID 25376742 DOI: 10.1111/cbdd.12473  0.56
2015 Bayer A, Delorme-Axford E, Sleigher C, Frey TK, Trobaugh DW, Klimstra WB, Emert-Sedlak LA, Smithgall TE, Kinchington PR, Vadia S, Seveau S, Boyle JP, Coyne CB, Sadovsky Y. Human trophoblasts confer resistance to viruses implicated in perinatal infection. American Journal of Obstetrics and Gynecology. 212: 71.e1-8. PMID 25108145 DOI: 10.1016/j.ajog.2014.07.060  0.56
2014 Zhang X, Simerly C, Hartnett C, Schatten G, Smithgall TE. Src-family tyrosine kinase activities are essential for differentiation of human embryonic stem cells. Stem Cell Research. 13: 379-89. PMID 25305536 DOI: 10.1016/j.scr.2014.09.007  0.56
2014 Moroco JA, Craigo JK, Iacob RE, Wales TE, Engen JR, Smithgall TE. Differential sensitivity of Src-family kinases to activation by SH3 domain displacement. Plos One. 9: e105629. PMID 25144189 DOI: 10.1371/journal.pone.0105629  0.56
2014 Alvarado JJ, Tarafdar S, Yeh JI, Smithgall TE. Interaction with the Src homology (SH3-SH2) region of the Src-family kinase Hck structures the HIV-1 Nef dimer for kinase activation and effector recruitment. The Journal of Biological Chemistry. 289: 28539-53. PMID 25122770 DOI: 10.1074/jbc.M114.600031  0.56
2014 Tarafdar S, Poe JA, Smithgall TE. The accessory factor Nef links HIV-1 to Tec/Btk kinases in an Src homology 3 domain-dependent manner. The Journal of Biological Chemistry. 289: 15718-28. PMID 24722985 DOI: 10.1074/jbc.M114.572099  0.56
2014 Iyer PC, Zhao J, Emert-Sedlak LA, Moore KK, Smithgall TE, Day BW. Synthesis and structure-activity analysis of diphenylpyrazolodiazene inhibitors of the HIV-1 Nef virulence factor. Bioorganic & Medicinal Chemistry Letters. 24: 1702-6. PMID 24650642 DOI: 10.1016/j.bmcl.2014.02.045  0.56
2014 Poe JA, Vollmer L, Vogt A, Smithgall TE. Development and validation of a high-content bimolecular fluorescence complementation assay for small-molecule inhibitors of HIV-1 Nef dimerization Journal of Biomolecular Screening. 19: 556-565. PMID 24282155 DOI: 10.1177/1087057113513640  0.56
2013 Trible RP, Narute P, Emert-Sedlak LA, Alvarado JJ, Atkins K, Thomas L, Kodama T, Yanamala N, Korotchenko V, Day BW, Thomas G, Smithgall TE. Discovery of a diaminoquinoxaline benzenesulfonamide antagonist of HIV-1 Nef function using a yeast-based phenotypic screen. Retrovirology. 10: 135. PMID 24229420 DOI: 10.1186/1742-4690-10-135  0.56
2013 Perrone R, Nadai M, Poe JA, Frasson I, Palumbo M, Palù G, Smithgall TE, Richter SN. Formation of a unique cluster of G-quadruplex structures in the HIV-1 Nef coding region: implications for antiviral activity. Plos One. 8: e73121. PMID 24015290 DOI: 10.1371/journal.pone.0073121  0.84
2013 Perrone R, Nadai M, Frasson I, Poe JA, Butovskaya E, Smithgall TE, Palumbo M, Palù G, Richter SN. A dynamic G-quadruplex region regulates the HIV-1 long terminal repeat promoter. Journal of Medicinal Chemistry. 56: 6521-30. PMID 23865750 DOI: 10.1021/jm400914r  0.84
2013 Engen JR, Wales TE, Chen S, Marzluff EM, Hassell KM, Weis DD, Smithgall TE. Partial cooperative unfolding in proteins as observed by hydrogen exchange mass spectrometry. International Reviews in Physical Chemistry. 32: 96-127. PMID 23682200 DOI: 10.1080/0144235X.2012.751175  0.56
2013 Emert-Sedlak LA, Narute P, Shu ST, Poe JA, Shi H, Yanamala N, Alvarado JJ, Lazo JS, Yeh JI, Johnston PA, Smithgall TE. Effector kinase coupling enables high-throughput screens for direct HIV-1 Nef antagonists with antiretroviral activity. Chemistry & Biology. 20: 82-91. PMID 23352142 DOI: 10.1016/j.chembiol.2012.11.005  0.56
2013 Panjarian S, Iacob RE, Chen S, Engen JR, Smithgall TE. Structure and dynamic regulation of Abl kinases. The Journal of Biological Chemistry. 288: 5443-50. PMID 23316053 DOI: 10.1074/jbc.R112.438382  0.56
2013 Panjarian S, Iacob RE, Chen S, Wales TE, Engen JR, Smithgall TE. Enhanced SH3/linker interaction overcomes Abl kinase activation by gatekeeper and myristic acid binding pocket mutations and increases sensitivity to small molecule inhibitors. The Journal of Biological Chemistry. 288: 6116-29. PMID 23303187 DOI: 10.1074/jbc.M112.431312  0.56
2012 Hellwig S, Miduturu CV, Kanda S, Zhang J, Filippakopoulos P, Salah E, Deng X, Choi HG, Zhou W, Hur W, Knapp S, Gray NS, Smithgall TE. Small-molecule inhibitors of the c-Fes protein-tyrosine kinase. Chemistry & Biology. 19: 529-40. PMID 22520759 DOI: 10.1016/j.chembiol.2012.01.020  0.56
2012 Pene-Dumitrescu T, Shu ST, Wales TE, Alvarado JJ, Shi H, Narute P, Moroco JA, Yeh JI, Engen JR, Smithgall TE. HIV-1 Nef interaction influences the ATP-binding site of the Src-family kinase, Hck. Bmc Chemical Biology. 12: 1. PMID 22420777 DOI: 10.1186/1472-6769-12-1  0.56
2012 Greer PA, Kanda S, Smithgall TE. The contrasting oncogenic and tumor suppressor roles of FES. Frontiers in Bioscience (Scholar Edition). 4: 489-501. PMID 22202072  0.56
2011 Marcsisin SR, Narute PS, Emert-Sedlak LA, Kloczewiak M, Smithgall TE, Engen JR. On the solution conformation and dynamics of the HIV-1 viral infectivity factor. Journal of Molecular Biology. 410: 1008-22. PMID 21763503 DOI: 10.1016/j.jmb.2011.04.053  0.56
2011 Hellwig S, Smithgall TE. Structure and regulation of the c-Fes protein-tyrosine kinase. Frontiers in Bioscience (Landmark Edition). 16: 3146-55. PMID 21622225 DOI: 10.2741/3902  0.56
2010 Alvarado JJ, Betts L, Moroco JA, Smithgall TE, Yeh JI. Crystal structure of the Src family kinase Hck SH3-SH2 linker regulatory region supports an SH3-dominant activation mechanism. The Journal of Biological Chemistry. 285: 35455-61. PMID 20810664 DOI: 10.1074/jbc.M110.145102  0.56
2010 Dikeakos JD, Atkins KM, Thomas L, Emert-Sedlak L, Byeon IJ, Jung J, Ahn J, Wortman MD, Kukull B, Saito M, Koizumi H, Williamson DM, Hiyoshi M, Barklis E, Takiguchi M, ... ... Smithgall TE, et al. Small molecule inhibition of HIV-1-induced MHC-I down-regulation identifies a temporally regulated switch in Nef action. Molecular Biology of the Cell. 21: 3279-92. PMID 20702582 DOI: 10.1091/mbc.E10-05-0470  0.56
2010 de Groh ED, Swanhart LM, Cosentino CC, Jackson RL, Dai W, Kitchens CA, Day BW, Smithgall TE, Hukriede NA. Inhibition of histone deacetylase expands the renal progenitor cell population. Journal of the American Society of Nephrology : Jasn. 21: 794-802. PMID 20378823 DOI: 10.1681/ASN.2009080851  0.56
2009 Schmaier AA, Zou Z, Kazlauskas A, Emert-Sedlak L, Fong KP, Neeves KB, Maloney SF, Diamond SL, Kunapuli SP, Ware J, Brass LF, Smithgall TE, Saksela K, Kahn ML. Molecular priming of Lyn by GPVI enables an immune receptor to adopt a hemostatic role. Proceedings of the National Academy of Sciences of the United States of America. 106: 21167-72. PMID 19940238 DOI: 10.1073/pnas.0906436106  0.56
2009 Emert-Sedlak L, Kodama T, Lerner EC, Dai W, Foster C, Day BW, Lazo JS, Smithgall TE. Chemical library screens targeting an HIV-1 accessory factor/host cell kinase complex identify novel antiretroviral compounds. Acs Chemical Biology. 4: 939-47. PMID 19807124 DOI: 10.1021/cb900195c  0.56
2009 Poe JA, Smithgall TE. HIV-1 Nef dimerization is required for Nef-mediated receptor downregulation and viral replication. Journal of Molecular Biology. 394: 329-42. PMID 19781555 DOI: 10.1016/j.jmb.2009.09.047  0.84
2009 Choi Y, Seeliger MA, Panjarian SB, Kim H, Deng X, Sim T, Couch B, Koleske AJ, Smithgall TE, Gray NS. N-myristoylated c-Abl tyrosine kinase localizes to the endoplasmic reticulum upon binding to an allosteric inhibitor. The Journal of Biological Chemistry. 284: 29005-14. PMID 19679652 DOI: 10.1074/jbc.M109.026633  0.56
2009 Molina G, Vogt A, Bakan A, Dai W, Queiroz de Oliveira P, Znosko W, Smithgall TE, Bahar I, Lazo JS, Day BW, Tsang M. Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages. Nature Chemical Biology. 5: 680-7. PMID 19578332 DOI: 10.1038/nchembio.190  0.56
2009 Shaffer JM, Hellwig S, Smithgall TE. Bimolecular fluorescence complementation demonstrates that the c-Fes protein-tyrosine kinase forms constitutive oligomers in living cells. Biochemistry. 48: 4780-8. PMID 19382747 DOI: 10.1021/bi900238f  0.56
2009 Iacob RE, Pene-Dumitrescu T, Zhang J, Gray NS, Smithgall TE, Engen JR. Conformational disturbance in Abl kinase upon mutation and deregulation. Proceedings of the National Academy of Sciences of the United States of America. 106: 1386-91. PMID 19164531 DOI: 10.1073/pnas.0811912106  0.56
2009 Shaffer JM, Smithgall TE. Promoter methylation blocks FES protein-tyrosine kinase gene expression in colorectal cancer. Genes, Chromosomes & Cancer. 48: 272-84. PMID 19051325 DOI: 10.1002/gcc.20638  0.72
2008 Chen S, O'Reilly LP, Smithgall TE, Engen JR. Tyrosine phosphorylation in the SH3 domain disrupts negative regulatory interactions within the c-Abl kinase core. Journal of Molecular Biology. 383: 414-23. PMID 18775435 DOI: 10.1016/j.jmb.2008.08.040  0.56
2008 Engen JR, Wales TE, Hochrein JM, Meyn MA, Banu Ozkan S, Bahar I, Smithgall TE. Structure and dynamic regulation of Src-family kinases. Cellular and Molecular Life Sciences : Cmls. 65: 3058-73. PMID 18563293 DOI: 10.1007/s00018-008-8122-2  0.56
2008 Chen S, Dumitrescu TP, Smithgall TE, Engen JR. Abl N-terminal cap stabilization of SH3 domain dynamics. Biochemistry. 47: 5795-803. PMID 18452309 DOI: 10.1021/bi800446b  0.56
2007 Trible RP, Emert-Sedlak L, Wales TE, Ayyavoo V, Engen JR, Smithgall TE. Allosteric loss-of-function mutations in HIV-1 Nef from a long-term non-progressor. Journal of Molecular Biology. 374: 121-9. PMID 17920628 DOI: 10.1016/j.jmb.2007.09.009  0.56
2007 Chen S, Brier S, Smithgall TE, Engen JR. The Abl SH2-kinase linker naturally adopts a conformation competent for SH3 domain binding. Protein Science : a Publication of the Protein Society. 16: 572-81. PMID 17327393 DOI: 10.1110/ps.062631007  0.56
2007 Mitchell JL, Trible RP, Emert-Sedlak LA, Weis DD, Lerner EC, Applen JJ, Sefton BM, Smithgall TE, Engen JR. Functional characterization and conformational analysis of the Herpesvirus saimiri Tip-C484 protein. Journal of Molecular Biology. 366: 1282-93. PMID 17207813 DOI: 10.1016/j.jmb.2006.12.026  0.56
2006 Chong YP, Chan AS, Chan KC, Williamson NA, Lerner EC, Smithgall TE, Bjorge JD, Fujita DJ, Purcell AW, Scholz G, Mulhern TD, Cheng HC. C-terminal Src kinase-homologous kinase (CHK), a unique inhibitor inactivating multiple active conformations of Src family tyrosine kinases. The Journal of Biological Chemistry. 281: 32988-99. PMID 16959780 DOI: 10.1074/jbc.M602951200  0.56
2006 Meyn MA, Wilson MB, Abdi FA, Fahey N, Schiavone AP, Wu J, Hochrein JM, Engen JR, Smithgall TE. Src family kinases phosphorylate the Bcr-Abl SH3-SH2 region and modulate Bcr-Abl transforming activity. The Journal of Biological Chemistry. 281: 30907-16. PMID 16912036 DOI: 10.1074/jbc.M605902200  0.56
2006 Trible RP, Emert-Sedlak L, Smithgall TE. HIV-1 Nef selectively activates Src family kinases Hck, Lyn, and c-Src through direct SH3 domain interaction. The Journal of Biological Chemistry. 281: 27029-38. PMID 16849330 DOI: 10.1074/jbc.M601128200  0.64
2006 Delfino FJ, Shaffer JM, Smithgall TE. The KRAB-associated co-repressor KAP-1 is a coiled-coil binding partner, substrate and activator of the c-Fes protein tyrosine kinase. The Biochemical Journal. 399: 141-50. PMID 16792528 DOI: 10.1042/BJ20060194  0.72
2006 Hochrein JM, Wales TE, Lerner EC, Schiavone AP, Smithgall TE, Engen JR. Conformational features of the full-length HIV and SIV Nef proteins determined by mass spectrometry. Biochemistry. 45: 7733-9. PMID 16784224 DOI: 10.1021/bi060438x  0.56
2006 Delfino FJ, Stevenson H, Smithgall TE. A growth-suppressive function for the c-fes protein-tyrosine kinase in colorectal cancer. The Journal of Biological Chemistry. 281: 8829-35. PMID 16455651 DOI: 10.1074/jbc.M507331200  0.56
2006 Hochrein JM, Lerner EC, Schiavone AP, Smithgall TE, Engen JR. An examination of dynamics crosstalk between SH2 and SH3 domains by hydrogen/deuterium exchange and mass spectrometry. Protein Science : a Publication of the Protein Society. 15: 65-73. PMID 16322569 DOI: 10.1110/ps.051782206  0.56
2005 Lerner EC, Trible RP, Schiavone AP, Hochrein JM, Engen JR, Smithgall TE. Activation of the Src family kinase Hck without SH3-linker release. The Journal of Biological Chemistry. 280: 40832-7. PMID 16210316 DOI: 10.1074/jbc.M508782200  0.56
2005 Meyn MA, Schreiner SJ, Dumitrescu TP, Nau GJ, Smithgall TE. SRC family kinase activity is required for murine embryonic stem cell growth and differentiation. Molecular Pharmacology. 68: 1320-30. PMID 15985613 DOI: 10.1124/mol.104.010231  0.56
2004 Laurent CE, Delfino FJ, Cheng HY, Smithgall TE. The human c-Fes tyrosine kinase binds tubulin and microtubules through separate domains and promotes microtubule assembly. Molecular and Cellular Biology. 24: 9351-8. PMID 15485904 DOI: 10.1128/MCB.24.21.9351-9358.2004  0.44
2003 Takashima Y, Delfino FJ, Engen JR, Superti-Furga G, Smithgall TE. Regulation of c-Fes tyrosine kinase activity by coiled-coil and SH2 domains: analysis with Saccharomyces cerevisiae. Biochemistry. 42: 3567-74. PMID 12653561 DOI: 10.1021/bi0272499  0.56
2001 Gmeiner WH, Xu I, Horita DA, Smithgall TE, Engen JR, Smith DL, Byrd RA. Intramolecular binding of a proximal PPII helix to an SH3 domain in the fusion protein SH3Hck : PPIIhGAP. Cell Biochemistry and Biophysics. 35: 115-26. PMID 11892787 DOI: 10.1385/CBB:35:2:115  0.56
2001 Xie S, Wang Y, Liu J, Sun T, Wilson MB, Smithgall TE, Arlinghaus RB. Involvement of Jak2 tyrosine phosphorylation in Bcr-Abl transformation. Oncogene. 20: 6188-95. PMID 11593427 DOI: 10.1038/sj.onc.1204834  0.56
2000 Zhang Y, Turkson J, Carter-Su C, Smithgall T, Levitzki A, Kraker A, Krolewski JJ, Medveczky P, Jove R. Activation of Stat3 in v-Src-transformed fibroblasts requires cooperation of Jak1 kinase activity. The Journal of Biological Chemistry. 275: 24935-44. PMID 10823829 DOI: 10.1074/jbc.M002383200  0.56
2000 Glover RT, Angiolieri M, Kelly S, Monaghan DT, Wang JY, Smithgall TE, Buller AL. Interaction of the N-methyl-D-aspartic acid receptor NR2D subunit with the c-Abl tyrosine kinase. The Journal of Biological Chemistry. 275: 12725-9. PMID 10777567 DOI: 10.1074/jbc.275.17.12725  0.56
2000 Horita DA, Zhang W, Smithgall TE, Gmeiner WH, Byrd RA. Dynamics of the Hck-SH3 domain: Comparison of experiment with multiple molecular dynamics simulations Protein Science. 9: 95-103. PMID 10739251 DOI: 10.1110/ps.9.1.95  0.56
1999 Engen JR, Gmeiner WH, Smithgall TE, Smith DL. Hydrogen exchange shows peptide binding stabilizes motions in Hck SH2. Biochemistry. 38: 8926-35. PMID 10413466 DOI: 10.1021/bi982611y  0.56
1999 Peters KL, Smithgall TE. Tyrosine phosphorylation enhances the SH2 domain-binding activity of Bcr and inhibits Bcr interaction with 14-3-3 proteins Cellular Signalling. 11: 507-514. PMID 10405761 DOI: 10.1016/S0898-6568(99)00021-2  0.56
1999 Engen JR, Smithgall TE, Gmeiner WH, Smith DL. Comparison of SH3 and SH2 domain dynamics when expressed alone or in an SH(3+2) construct: the role of protein dynamics in functional regulation. Journal of Molecular Biology. 287: 645-56. PMID 10092465 DOI: 10.1006/jmbi.1999.2619  0.56
1998 Ahmad I, Acharya HR, Rogers JA, Shibata A, Smithgall TE, Dooley CM. The role of NeuroD as a differentiation factor in the mammalian retina. Journal of Molecular Neuroscience : Mn. 11: 165-78. PMID 10096043 DOI: 10.1385/JMN:11:2:165  0.56
1998 Smithgall TE, Rogers JA, Peters KL, Li J, Briggs SD, Lionberger JM, Cheng H, Shibata A, Scholtz B, Schreiner S, Dunham N. The c-Fes family of protein-tyrosine kinases Critical Reviews in Oncogenesis. 9: 43-62. PMID 9754447 DOI: 10.1615/CritRevOncog.v9.i1.40  0.56
1998 Horita DA, Baldisseri DM, Zhang W, Altieri AS, Smithgall TE, Gmeiner WH, Byrd RA. Solution structure of the human Hck SH3 domain and identification of its ligand binding site Journal of Molecular Biology. 278: 253-265. PMID 9571048 DOI: 10.1006/jmbi.1998.1690  0.56
1998 Nelson KL, Rogers JA, Bowman TL, Jove R, Smithgall TE. Activation of STAT3 by the c-Fes protein-tyrosine kinase Journal of Biological Chemistry. 273: 7072-7077. PMID 9507017 DOI: 10.1074/jbc.273.12.7072  0.56
1997 Engen JR, Smithgall TE, Gmeiner WH, Smith DL. Identification and localization of slow, natural, cooperative unfolding in the hematopoietic cell kinase SH3 domain by amide hydrogen exchange and mass spectrometry. Biochemistry. 36: 14384-91. PMID 9398156 DOI: 10.1021/bi971635m  0.56
1996 Rogers JA, Read RD, Li J, Peters KL, Smithgall TE. Autophosphorylation of the Fes tyrosine kinase. Evidence for an intermolecular mechanism involving two kinase domain tyrosine residues Journal of Biological Chemistry. 271: 17519-17525. PMID 8663427 DOI: 10.1074/jbc.271.29.17519  0.56
1996 Bukrinskaya AG, Ghorpade A, Heinzinger NK, Smithgall TE, Lewis RE, Stevenson M. Phosphorylation-dependent human immunodeficiency virus type 1 infection and nuclear targeting of viral DNA. Proceedings of the National Academy of Sciences of the United States of America. 93: 367-71. PMID 8552640 DOI: 10.1073/pnas.93.1.367  0.56
1995 Bryant SS, Briggs S, Smithgall TE, Martin GA, McCormick F, Chang - JH, Parsons SJ, Jove R. Two SH2 domains of p120 Ras GTPase-activating protein bind synergistically to tyrosine phosphorylated p190 Rho GTPase-activating protein Journal of Biological Chemistry. 270: 17947-17952. PMID 7629101 DOI: 10.1074/jbc.270.30.17947  0.56
1995 Maru Y, Peters KL, Afar DEH, Shibuya M, Witte ON, Smithgall TE. Tyrosine phosphorylation of BCR by FPS/FES protein-tyrosine kinases induces association of BCR with GRB-2/SOS Molecular and Cellular Biology. 15: 835-842. PMID 7529874 DOI: 10.1128/MCB.15.2.835  0.56
1991 Smithgall TE, Johnston JB, Bustin M, Glazer RI. Elevated expression of the c-fes proto-oncogene in adult human myeloid leukemia cells in the absence of gene amplification. Journal of the National Cancer Institute. 83: 42-6. PMID 1984516 DOI: 10.1093/jnci/83.1.42  0.56
1989 Penning TM, Sharp RB, Smithgall TE. Non-K-region o-quinones as enzyme-generated inactivators of dihydrodiol dehydrogenase Biochemistry. 28: 4505-4511. PMID 2669957 DOI: 10.1021/bi00436a057  0.56
1988 Smithgall TE, Penning TM. Electrophoretic and immunochemical characterization of 3α-hydroxysteroid/dihydrodiol dehydrogenases of rat tissues Biochemical Journal. 254: 715-721. PMID 3196287 DOI: 10.1042/bj2540715  0.56
1986 Penning TM, Smithgall TE, Askonas LJ, Sharp RB. Rat liver 3α-hydroxysteroid dehydrogenase Steroids. 47: 223-247. PMID 3473753 DOI: 10.1016/0039-128X(86)90094-2  0.56
1986 Smithgall TE, Penning TM. Inhibition of trans-dihydrodiol oxidation by the non-steroidal anti-inflammatory drugs Carcinogenesis. 7: 583-588. PMID 3457649 DOI: 10.1093/carcin/7.4.583  0.56
1985 Smithgall TE, Penning TM. Indomethacin-sensitive 3α-hydroxysteroid dehydrogenase in rat tissues Biochemical Pharmacology. 34: 831-835. PMID 3856432 DOI: 10.1016/0006-2952(85)90763-4  0.56
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