Stephen W. Ragsdale - Publications

Affiliations: 
1987-1991 Chemistry University of Wisconsin-Milwaukee, Milwaukee, WI 
 1991-2007 Biochemistry The University of Nebraska - Lincoln, Lincoln, NE 
 2007- Biological Chemistry The University of Michigan Medical School 
Area:
Biochemistry, Bioinorganic Chemistry
Website:
https://medicine.umich.edu/dept/biochem/stephen-ragsdale-phd

143 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Maitra D, Carter EL, Richardson R, Rittié L, Basrur V, Zhang H, Nesvizhskii AI, Osawa Y, Wolf MW, Ragsdale SW, Lehnert N, Herrmann H, Omary MB. Oxygen and conformation dependent protein oxidation and aggregation by porphyrins in hepatocytes and light-exposed cells. Cellular and Molecular Gastroenterology and Hepatology. PMID 31173894 DOI: 10.1016/j.jcmgh.2019.05.010  0.56
2019 Kochert BA, Fleischhacker AS, Wales TE, Becker DF, Engen JR, Ragsdale SW. Dynamic and structural differences between heme oxygenase-1 and -2 are due to differences in their C-terminal regions. The Journal of Biological Chemistry. PMID 30944174 DOI: 10.1074/jbc.RA119.008592  1
2018 Zhang L, Can M, Ragsdale SW, Armstrong FA. Fast and Selective Photoreduction of CO to CO Catalyzed by a Complex of Carbon Monoxide Dehydrogenase, TiO, and Ag Nanoclusters. Acs Catalysis. 8: 2789-2795. PMID 31448153 DOI: 10.1021/acscatal.7b04308  0.56
2018 Burton R, Can M, Esckilsen D, Wiley S, Ragsdale SW. Production and properties of enzymes that activate and produce carbon monoxide. Methods in Enzymology. 613: 297-324. PMID 30509471 DOI: 10.1016/bs.mie.2018.10.005  0.56
2018 Fleischhacker AS, Ragsdale SW. An unlikely heme chaperone confirmed at last. The Journal of Biological Chemistry. 293: 14569-14570. PMID 30217868 DOI: 10.1074/jbc.H118.005247  0.52
2018 Chen PY, Aman H, Can M, Ragsdale SW, Drennan CL. Binding site for coenzyme A revealed in the structure of pyruvate:ferredoxin oxidoreductase from. Proceedings of the National Academy of Sciences of the United States of America. PMID 29581263 DOI: 10.1073/pnas.1722329115  0.72
2017 Fleischhacker AS, Carter E, Ragsdale S. Redox regulation of heme oxygenase-2 and the transcription factor, Rev-erb, through heme regulatory motifs. Antioxidants & Redox Signaling. PMID 28990415 DOI: 10.1089/ars.2017.7368  0.52
2017 Pierce E, Mansoorabadi SO, Can M, Reed GH, Ragsdale SW. Properties of intermediates in the catalytic cycle of oxalate oxidoreductase and its suicide inactivation by pyruvate. Biochemistry. PMID 28514140 DOI: 10.1021/acs.biochem.7b00222  0.56
2017 Carter EL, Ramirez Y, Ragsdale SW. The Heme Regulatory Motif of Nuclear Receptor Rev-erbβ is a Key Mediator of Heme and Redox Signaling in Circadian Rhythm Maintenance and Metabolism. The Journal of Biological Chemistry. PMID 28500133 DOI: 10.1074/jbc.M117.783118  0.56
2017 Can M, Giles LJ, Ragsdale SW, Sarangi R. X-ray Absorption Spectroscopy Reveals an Organometallic Ni-C bond in the CO-treated Form of Acetyl-CoA Synthase. Biochemistry. PMID 28186407 DOI: 10.1021/acs.biochem.6b00983  0.56
2016 Pearl NM, Wilcoxen J, Im S, Kunz RC, Darty JE, Britt RD, Ragsdale SW, Waskell LA. Protonation of the hydroperoxo intermediate of cytochrome P450 2B4 is slower in the presence of cytochrome P450 reductase than in the presence of cytochrome b5. Biochemistry. PMID 27797496 DOI: 10.1021/acs.biochem.6b00996  0.92
2016 Wongnate T, Sliwa D, Ginovska B, Smith D, Wolf MW, Lehnert N, Raugei S, Ragsdale SW. The radical mechanism of biological methane synthesis by methyl-coenzyme M reductase. Science (New York, N.Y.). 352: 953-8. PMID 27199421 DOI: 10.1126/science.aaf0616  1
2015 Gibson MI, Chen PY, Johnson AC, Pierce E, Can M, Ragsdale SW, Drennan CL. One-carbon chemistry of oxalate oxidoreductase captured by X-ray crystallography. Proceedings of the National Academy of Sciences of the United States of America. PMID 26712008 DOI: 10.1073/pnas.1518537113  1
2015 Carter EL, Gupta N, Ragsdale SW. High Affinity Heme Binding to a Heme Regulatory Motif on the Nuclear Receptor Rev-erbβ Leads to its Degradation and Indirectly Regulates its Interaction with Nuclear Receptor Corepressor. The Journal of Biological Chemistry. PMID 26670607 DOI: 10.1074/jbc.M115.670281  1
2015 Davydov R, Fleischhacker AS, Bagai I, Hoffman BM, Ragsdale SW. Comparison of the Mechanisms of Heme Hydroxylation by Heme Oxygenases-1 and -2: Kinetic and Cryoreduction Studies. Biochemistry. PMID 26652036 DOI: 10.1021/acs.biochem.5b00943  1
2015 Wang VC, Islam ST, Can M, Ragsdale SW, Armstrong FA. Investigations by Protein Film Electrochemistry of Alternative Reactions of Nickel-Containing Carbon Monoxide Dehydrogenase. The Journal of Physical Chemistry. B. PMID 26176986 DOI: 10.1021/acs.jpcb.5b03098  1
2015 Gibson MI, Brignole EJ, Pierce E, Can M, Ragsdale SW, Drennan CL. The Structure of an Oxalate Oxidoreductase Provides Insight into Microbial 2-Oxoacid Metabolism. Biochemistry. 54: 4112-20. PMID 26061898 DOI: 10.1021/acs.biochem.5b00521  1
2015 Fleischhacker AS, Sharma A, Choi M, Spencer AM, Bagai I, Hoffman BM, Ragsdale SW. The C-terminal heme regulatory motifs of heme oxygenase-2 are redox-regulated heme binding sites. Biochemistry. 54: 2709-18. PMID 25853617 DOI: 10.1021/acs.biochem.5b00266  1
2015 Bagai I, Sarangi R, Fleischhacker AS, Sharma A, Hoffman BM, Zuiderweg ER, Ragsdale SW. Spectroscopic studies reveal that the heme regulatory motifs of heme oxygenase-2 are dynamically disordered and exhibit redox-dependent interaction with heme. Biochemistry. 54: 2693-708. PMID 25849895 DOI: 10.1021/bi501489r  1
2015 Wongnate T, Ragsdale SW. The reaction mechanism of methyl-coenzyme M reductase: how an enzyme enforces strict binding order. The Journal of Biological Chemistry. 290: 9322-34. PMID 25691570 DOI: 10.1074/jbc.M115.636761  1
2014 Ragsdale SW. Biochemistry of methyl-coenzyme M reductase: the nickel metalloenzyme that catalyzes the final step in synthesis and the first step in anaerobic oxidation of the greenhouse gas methane. Metal Ions in Life Sciences. 14: 125-45. PMID 25416393 DOI: 10.1007/978-94-017-9269-1_6  1
2014 Wang VC, Ragsdale SW, Armstrong FA. Investigations of the efficient electrocatalytic interconversions of carbon dioxide and carbon monoxide by nickel-containing carbon monoxide dehydrogenases. Metal Ions in Life Sciences. 14: 71-97. PMID 25416391 DOI: 10.1007/978-94-017-9269-1_4  1
2014 Bachmeier A, Hall S, Ragsdale SW, Armstrong FA. Selective visible-light-driven CO2 reduction on a p-type dye-sensitized NiO photocathode. Journal of the American Chemical Society. 136: 13518-21. PMID 25237714 DOI: 10.1021/ja506998b  1
2014 Spencer AL, Bagai I, Becker DF, Zuiderweg ER, Ragsdale SW. Protein/protein interactions in the mammalian heme degradation pathway: heme oxygenase-2, cytochrome P450 reductase, and biliverdin reductase. The Journal of Biological Chemistry. 289: 29836-58. PMID 25196843 DOI: 10.1074/jbc.M114.582783  1
2014 Can M, Armstrong FA, Ragsdale SW. Structure, function, and mechanism of the nickel metalloenzymes, CO dehydrogenase, and acetyl-CoA synthase. Chemical Reviews. 114: 4149-74. PMID 24521136 DOI: 10.1021/cr400461p  1
2014 Carter EL, Ragsdale SW. Modulation of nuclear receptor function by cellular redox poise. Journal of Inorganic Biochemistry. 133: 92-103. PMID 24495544 DOI: 10.1016/j.jinorgbio.2014.01.005  1
2013 Bachmeier A, Wang VC, Woolerton TW, Bell S, Fontecilla-Camps JC, Can M, Ragsdale SW, Chaudhary YS, Armstrong FA. How light-harvesting semiconductors can alter the bias of reversible electrocatalysts in favor of H2 production and CO2 reduction. Journal of the American Chemical Society. 135: 15026-32. PMID 24070184 DOI: 10.1021/ja4042675  1
2013 Wang VC, Ragsdale SW, Armstrong FA. Investigations of two bidirectional carbon monoxide dehydrogenases from Carboxydothermus hydrogenoformans by protein film electrochemistry. Chembiochem : a European Journal of Chemical Biology. 14: 1845-51. PMID 24002936 DOI: 10.1002/cbic.201300270  1
2013 Appel AM, Bercaw JE, Bocarsly AB, Dobbek H, DuBois DL, Dupuis M, Ferry JG, Fujita E, Hille R, Kenis PJ, Kerfeld CA, Morris RH, Peden CH, Portis AR, Ragsdale SW, et al. Frontiers, opportunities, and challenges in biochemical and chemical catalysis of CO2 fixation. Chemical Reviews. 113: 6621-58. PMID 23767781 DOI: 10.1021/cr300463y  1
2013 Zhou Y, Dorchak AE, Ragsdale SW. In vivo activation of methyl-coenzyme M reductase by carbon monoxide. Frontiers in Microbiology. 4: 69. PMID 23554601 DOI: 10.3389/fmicb.2013.00069  1
2013 Wang VC, Can M, Pierce E, Ragsdale SW, Armstrong FA. A unified electrocatalytic description of the action of inhibitors of nickel carbon monoxide dehydrogenase. Journal of the American Chemical Society. 135: 2198-206. PMID 23368960 DOI: 10.1021/ja308493k  1
2012 Ando N, Kung Y, Can M, Bender G, Ragsdale SW, Drennan CL. Transient B12-dependent methyltransferase complexes revealed by small-angle X-ray scattering. Journal of the American Chemical Society. 134: 17945-54. PMID 23051056 DOI: 10.1021/ja3055782  1
2012 Ragsdale SW, Yi L, Bender G, Gupta N, Kung Y, Yan L, Stich TA, Doukov T, Leichert L, Jenkins PM, Bianchetti CM, George SJ, Cramer SP, Britt RD, Jakob U, et al. Redox, haem and CO in enzymatic catalysis and regulation. Biochemical Society Transactions. 40: 501-7. PMID 22616859 DOI: 10.1042/BST20120083  1
2012 Kung Y, Ando N, Doukov TI, Blasiak LC, Bender G, Seravalli J, Ragsdale SW, Drennan CL. Visualizing molecular juggling within a B12-dependent methyltransferase complex. Nature. 484: 265-9. PMID 22419154 DOI: 10.1038/nature10916  1
2012 Reed GH, Ragsdale SW, Mansoorabadi SO. Radical reactions of thiamin pyrophosphate in 2-oxoacid oxidoreductases. Biochimica Et Biophysica Acta. 1824: 1291-8. PMID 22178227 DOI: 10.1016/j.bbapap.2011.11.010  1
2012 Chaudhary YS, Woolerton TW, Allen CS, Warner JH, Pierce E, Ragsdale SW, Armstrong FA. Visible light-driven CO2 reduction by enzyme coupled CdS nanocrystals. Chemical Communications (Cambridge, England). 48: 58-60. PMID 22083268 DOI: 10.1039/c1cc16107e  1
2011 Bender G, Pierce E, Hill JA, Darty JE, Ragsdale SW. Metal centers in the anaerobic microbial metabolism of CO and CO2. Metallomics : Integrated Biometal Science. 3: 797-815. PMID 21647480 DOI: 10.1039/c1mt00042j  1
2011 Ragsdale SW. Biochemistry: How two amino acids become one. Nature. 471: 583-4. PMID 21455167 DOI: 10.1038/471583a  1
2011 Cedervall PE, Dey M, Li X, Sarangi R, Hedman B, Ragsdale SW, Wilmot CM. Structural analysis of a Ni-methyl species in methyl-coenzyme M reductase from Methanothermobacter marburgensis. Journal of the American Chemical Society. 133: 5626-8. PMID 21438550 DOI: 10.1021/ja110492p  1
2011 Rosenzweig AC, Ragsdale SW. The production and consumption of methane by microorganisms is central to the global carbon cycle. Preface. Methods in Enzymology. 494: xv-xvi. PMID 21402206 DOI: 10.1016/B978-0-12-385112-3.00017-2  1
2011 Bagai I, Ragsdale SW, Zuiderweg ER. Pseudo-4D triple resonance experiments to resolve HN overlap in the backbone assignment of unfolded proteins. Journal of Biomolecular Nmr. 49: 69-74. PMID 21190062 DOI: 10.1007/s10858-010-9465-1  1
2011 Bender G, Ragsdale SW. Evidence that ferredoxin interfaces with an internal redox shuttle in Acetyl-CoA synthase during reductive activation and catalysis. Biochemistry. 50: 276-86. PMID 21141812 DOI: 10.1021/bi101511r  1
2011 Gupta N, Ragsdale SW. Thiol-disulfide redox dependence of heme binding and heme ligand switching in nuclear hormone receptor rev-erb{beta}. The Journal of Biological Chemistry. 286: 4392-403. PMID 21123168 DOI: 10.1074/jbc.M110.193466  1
2011 Ragsdale SW, Yi L. Thiol/Disulfide redox switches in the regulation of heme binding to proteins. Antioxidants & Redox Signaling. 14: 1039-47. PMID 20812781 DOI: 10.1089/ars.2010.3436  1
2010 Dey M, Li X, Kunz RC, Ragsdale SW. Detection of organometallic and radical intermediates in the catalytic mechanism of methyl-coenzyme M reductase using the natural substrate methyl-coenzyme M and a coenzyme B substrate analogue. Biochemistry. 49: 10902-11. PMID 21090696 DOI: 10.1021/bi101562m  1
2010 Pierce E, Becker DF, Ragsdale SW. Identification and characterization of oxalate oxidoreductase, a novel thiamine pyrophosphate-dependent 2-oxoacid oxidoreductase that enables anaerobic growth on oxalate. The Journal of Biological Chemistry. 285: 40515-24. PMID 20956531 DOI: 10.1074/jbc.M110.155739  1
2010 Dey M, Li X, Zhou Y, Ragsdale SW. Evidence for organometallic intermediates in bacterial methane formation involving the nickel coenzyme F₄₃₀. Metal Ions in Life Sciences. 7: 71-110. PMID 20877805 DOI: 10.1039/BK9781847551771-00071  1
2010 Seravalli J, Ragsdale SW. Expanding the biological periodic table. Chemistry & Biology. 17: 793-4. PMID 20797607 DOI: 10.1016/j.chembiol.2010.08.004  1
2010 Cedervall PE, Dey M, Pearson AR, Ragsdale SW, Wilmot CM. Structural insight into methyl-coenzyme M reductase chemistry using coenzyme B analogues . Biochemistry. 49: 7683-93. PMID 20707311 DOI: 10.1021/bi100458d  1
2010 Bender G, Stich TA, Yan L, Britt RD, Cramer SP, Ragsdale SW. Infrared and EPR spectroscopic characterization of a Ni(I) species formed by photolysis of a catalytically competent Ni(I)-CO intermediate in the acetyl-CoA synthase reaction. Biochemistry. 49: 7516-23. PMID 20669901 DOI: 10.1021/bi1010128  1
2010 Li X, Telser J, Kunz RC, Hoffman BM, Gerfen G, Ragsdale SW. Observation of organometallic and radical intermediates formed during the reaction of methyl-coenzyme M reductase with bromoethanesulfonate. Biochemistry. 49: 6866-76. PMID 20597483 DOI: 10.1021/bi100650m  1
2010 Gardner JD, Yi L, Ragsdale SW, Brunold TC. Spectroscopic insights into axial ligation and active-site H-bonding in substrate-bound human heme oxygenase-2. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 15: 1117-27. PMID 20502928 DOI: 10.1007/s00775-010-0672-8  1
2010 Yi L, Morgan JT, Ragsdale SW. Identification of a thiol/disulfide redox switch in the human BK channel that controls its affinity for heme and CO. The Journal of Biological Chemistry. 285: 20117-27. PMID 20427280 DOI: 10.1074/jbc.M110.116483  1
2010 Woolerton TW, Sheard S, Reisner E, Pierce E, Ragsdale SW, Armstrong FA. Efficient and clean photoreduction of CO(2) to CO by enzyme-modified TiO(2) nanoparticles using visible light. Journal of the American Chemical Society. 132: 2132-3. PMID 20121138 DOI: 10.1021/ja910091z  1
2009 Lazarus O, Woolerton TW, Parkin A, Lukey MJ, Reisner E, Seravalli J, Pierce E, Ragsdale SW, Sargent F, Armstrong FA. Water-gas shift reaction catalyzed by redox enzymes on conducting graphite platelets. Journal of the American Chemical Society. 131: 14154-5. PMID 19807170 DOI: 10.1021/ja905797w  1
2009 Kung Y, Doukov TI, Seravalli J, Ragsdale SW, Drennan CL. Crystallographic snapshots of cyanide- and water-bound C-clusters from bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase. Biochemistry. 48: 7432-40. PMID 19583207 DOI: 10.1021/bi900574h  1
2009 Yi L, Jenkins PM, Leichert LI, Jakob U, Martens JR, Ragsdale SW. Heme regulatory motifs in heme oxygenase-2 form a thiol/disulfide redox switch that responds to the cellular redox state. The Journal of Biological Chemistry. 284: 20556-61. PMID 19473966 DOI: 10.1074/jbc.M109.015651  1
2009 Ragsdale SW. Nickel-based Enzyme Systems. The Journal of Biological Chemistry. 284: 18571-5. PMID 19363030 DOI: 10.1074/jbc.R900020200  1
2009 Sarangi R, Dey M, Ragsdale SW. Geometric and electronic structures of the Ni(I) and methyl-Ni(III) intermediates of methyl-coenzyme M reductase. Biochemistry. 48: 3146-56. PMID 19243132 DOI: 10.1021/bi900087w  1
2008 Ragsdale SW. Catalysis of methyl group transfers involving tetrahydrofolate and B(12). Vitamins and Hormones. 79: 293-324. PMID 18804699 DOI: 10.1016/S0083-6729(08)00410-X  1
2008 Ragsdale SW, Pierce E. Acetogenesis and the Wood-Ljungdahl pathway of CO(2) fixation. Biochimica Et Biophysica Acta. 1784: 1873-98. PMID 18801467 DOI: 10.1016/j.bbapap.2008.08.012  1
2008 Gupta N, Ragsdale SW. Dual roles of an essential cysteine residue in activity of a redox-regulated bacterial transcriptional activator. The Journal of Biological Chemistry. 283: 28721-8. PMID 18687692 DOI: 10.1074/jbc.M800630200  1
2008 Pierce E, Xie G, Barabote RD, Saunders E, Han CS, Detter JC, Richardson P, Brettin TS, Das A, Ljungdahl LG, Ragsdale SW. The complete genome sequence of Moorella thermoacetica (f. Clostridium thermoaceticum). Environmental Microbiology. 10: 2550-73. PMID 18631365 DOI: 10.1111/j.1462-2920.2008.01679.x  1
2008 Seravalli J, Ragsdale SW. 13C NMR characterization of an exchange reaction between CO and CO2 catalyzed by carbon monoxide dehydrogenase. Biochemistry. 47: 6770-81. PMID 18589895 DOI: 10.1021/bi8004522  1
2008 Ragsdale SW. Enzymology of the wood-Ljungdahl pathway of acetogenesis. Annals of the New York Academy of Sciences. 1125: 129-36. PMID 18378591 DOI: 10.1196/annals.1419.015  1
2008 Doukov TI, Blasiak LC, Seravalli J, Ragsdale SW, Drennan CL. Xenon in and at the end of the tunnel of bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase. Biochemistry. 47: 3474-83. PMID 18293927 DOI: 10.1021/bi702386t  1
2008 Kunz RC, Dey M, Ragsdale SW. Characterization of the thioether product formed from the thiolytic cleavage of the alkyl-nickel bond in methyl-coenzyme M reductase. Biochemistry. 47: 2661-7. PMID 18220418 DOI: 10.1021/bi701942w  1
2008 Seravalli J, Ragsdale SW. Pulse-chase studies of the synthesis of acetyl-CoA by carbon monoxide dehydrogenase/acetyl-CoA synthase: evidence for a random mechanism of methyl and carbonyl addition. The Journal of Biological Chemistry. 283: 8384-94. PMID 18203715 DOI: 10.1074/jbc.M709470200  1
2007 Bianchetti CM, Yi L, Ragsdale SW, Phillips GN. Comparison of apo- and heme-bound crystal structures of a truncated human heme oxygenase-2. The Journal of Biological Chemistry. 282: 37624-31. PMID 17965015 DOI: 10.1074/jbc.M707396200  1
2007 Dey M, Kunz RC, Lyons DM, Ragsdale SW. Characterization of alkyl-nickel adducts generated by reaction of methyl-coenzyme m reductase with brominated acids. Biochemistry. 46: 11969-78. PMID 17902704 DOI: 10.1021/bi700925n  1
2007 Ragsdale SW. Nickel and the carbon cycle. Journal of Inorganic Biochemistry. 101: 1657-66. PMID 17716738 DOI: 10.1016/j.jinorgbio.2007.07.014  1
2007 Dey M, Telser J, Kunz RC, Lees NS, Ragsdale SW, Hoffman BM. Biochemical and spectroscopic studies of the electronic structure and reactivity of a methyl-Ni species formed on methyl-coenzyme M reductase. Journal of the American Chemical Society. 129: 11030-2. PMID 17711283 DOI: 10.1021/ja074556z  1
2007 Parkin A, Seravalli J, Vincent KA, Ragsdale SW, Armstrong FA. Rapid and efficient electrocatalytic CO2/CO interconversions by Carboxydothermus hydrogenoformans CO dehydrogenase I on an electrode. Journal of the American Chemical Society. 129: 10328-9. PMID 17672466 DOI: 10.1021/ja073643o  1
2007 Yi L, Ragsdale SW. Evidence that the heme regulatory motifs in heme oxygenase-2 serve as a thiol/disulfide redox switch regulating heme binding. The Journal of Biological Chemistry. 282: 21056-67. PMID 17540772 DOI: 10.1074/jbc.M700664200  1
2007 Doukov TI, Hemmi H, Drennan CL, Ragsdale SW. Structural and kinetic evidence for an extended hydrogen-bonding network in catalysis of methyl group transfer. Role of an active site asparagine residue in activation of methyl transfer by methyltransferases. The Journal of Biological Chemistry. 282: 6609-18. PMID 17172470 DOI: 10.1074/jbc.M609828200  1
2006 Dey M, Kunz RC, Van Heuvelen KM, Craft JL, Horng YC, Tang Q, Bocian DF, George SJ, Brunold TC, Ragsdale SW. Spectroscopic and computational studies of reduction of the metal versus the tetrapyrrole ring of coenzyme F430 from methyl-coenzyme M reductase. Biochemistry. 45: 11915-33. PMID 17002292 DOI: 10.1021/bi0613269  1
2006 Kunz RC, Horng YC, Ragsdale SW. Spectroscopic and kinetic studies of the reaction of bromopropanesulfonate with methyl-coenzyme M reductase. The Journal of Biological Chemistry. 281: 34663-76. PMID 16966321 DOI: 10.1074/jbc.M606715200  1
2006 Ragsdale SW. Metals and their scaffolds to promote difficult enzymatic reactions. Chemical Reviews. 106: 3317-37. PMID 16895330 DOI: 10.1021/cr0503153  1
2006 Pop SM, Gupta N, Raza AS, Ragsdale SW. Transcriptional activation of dehalorespiration. Identification of redox-active cysteines regulating dimerization and DNA binding. The Journal of Biological Chemistry. 281: 26382-90. PMID 16840784 DOI: 10.1074/jbc.M602158200  1
2006 Joyce MG, Levy C, Gábor K, Pop SM, Biehl BD, Doukov TI, Ryter JM, Mazon H, Smidt H, van den Heuvel RH, Ragsdale SW, van der Oost J, Leys D. CprK crystal structures reveal mechanism for transcriptional control of halorespiration. The Journal of Biological Chemistry. 281: 28318-25. PMID 16803881 DOI: 10.1074/jbc.M602654200  1
2006 Mansoorabadi SO, Seravalli J, Furdui C, Krymov V, Gerfen GJ, Begley TP, Melnick J, Ragsdale SW, Reed GH. EPR spectroscopic and computational characterization of the hydroxyethylidene-thiamine pyrophosphate radical intermediate of pyruvate:ferredoxin oxidoreductase. Biochemistry. 45: 7122-31. PMID 16752902 DOI: 10.1021/bi0602516  1
2006 Stich TA, Seravalli J, Venkateshrao S, Spiro TG, Ragsdale SW, Brunold TC. Spectroscopic studies of the corrinoid/iron-sulfur protein from Moorella thermoacetica. Journal of the American Chemical Society. 128: 5010-20. PMID 16608335 DOI: 10.1021/ja054690o  1
2006 Astashkin AV, Seravalli J, Mansoorabadi SO, Reed GH, Ragsdale SW. Pulsed electron paramagnetic resonance experiments identify the paramagnetic intermediates in the pyruvate ferredoxin oxidoreductase catalytic cycle. Journal of the American Chemical Society. 128: 3888-9. PMID 16551078 DOI: 10.1021/ja0585275  1
2006 Frantom PA, Seravalli J, Ragsdale SW, Fitzpatrick PF. Reduction and oxidation of the active site iron in tyrosine hydroxylase: kinetics and specificity. Biochemistry. 45: 2372-9. PMID 16475826 DOI: 10.1021/bi052283j  1
2005 George SJ, Seravalli J, Ragsdale SW. EPR and infrared spectroscopic evidence that a kinetically competent paramagnetic intermediate is formed when acetyl-coenzyme A synthase reacts with CO. Journal of the American Chemical Society. 127: 13500-1. PMID 16190705 DOI: 10.1021/ja0528329  1
2004 Ragsdale SW. Life with carbon monoxide. Critical Reviews in Biochemistry and Molecular Biology. 39: 165-95. PMID 15596550 DOI: 10.1080/10409230490496577  1
2004 Pop SM, Kolarik RJ, Ragsdale SW. Regulation of anaerobic dehalorespiration by the transcriptional activator CprK. The Journal of Biological Chemistry. 279: 49910-8. PMID 15381694 DOI: 10.1074/jbc.M409435200  1
2004 Dumitru RV, Ragsdale SW. Mechanism of 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase, a key enzyme in the methanopterin biosynthetic pathway. The Journal of Biological Chemistry. 279: 39389-95. PMID 15262968 DOI: 10.1074/jbc.M406442200  1
2004 Gu W, Seravalli J, Ragsdale SW, Cramer SP. CO-induced structural rearrangement of the C cluster in Carboxydothermus hydrogenoformans CO dehydrogenase-evidence from Ni K-edge X-ray absorption spectroscopy. Biochemistry. 43: 9029-35. PMID 15248760 DOI: 10.1021/bi036104e  1
2004 Drennan CL, Doukov TI, Ragsdale SW. The metalloclusters of carbon monoxide dehydrogenase/acetyl-CoA synthase: a story in pictures. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 9: 511-5. PMID 15221484 DOI: 10.1007/s00775-004-0563-y  1
2004 Craft JL, Horng YC, Ragsdale SW, Brunold TC. Nickel oxidation states of F(430) cofactor in methyl-coenzyme M reductase. Journal of the American Chemical Society. 126: 4068-9. PMID 15053571 DOI: 10.1021/ja038082p  1
2004 Seravalli J, Xiao Y, Gu W, Cramer SP, Antholine WE, Krymov V, Gerfen GJ, Ragsdale SW. Evidence that NiNi acetyl-CoA synthase is active and that the CuNi enzyme is not. Biochemistry. 43: 3944-55. PMID 15049702 DOI: 10.1021/bi036194n  1
2004 Craft JL, Horng YC, Ragsdale SW, Brunold TC. Spectroscopic and computational characterization of the nickel-containing F430 cofactor of methyl-coenzyme M reductase. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 9: 77-89. PMID 14663648 DOI: 10.1007/s00775-003-0499-7  1
2003 Chen J, Huang S, Seravalli J, Gutzman H, Swartz DJ, Ragsdale SW, Bagley KA. Infrared studies of carbon monoxide binding to carbon monoxide dehydrogenase/acetyl-CoA synthase from Moorella thermoacetica. Biochemistry. 42: 14822-30. PMID 14674756 DOI: 10.1021/bi0349470  1
2003 Dumitru R, Palencia H, Schroeder SD, DeMontigny BA, Takacs JM, Rasche ME, Miner JL, Ragsdale SW. Targeting methanopterin biosynthesis to inhibit methanogenesis. Applied and Environmental Microbiology. 69: 7236-41. PMID 14660371 DOI: 10.1128/AEM.69.12.7236-7241.2003  1
2003 Banerjee R, Ragsdale SW. The many faces of vitamin B12: catalysis by cobalamin-dependent enzymes. Annual Review of Biochemistry. 72: 209-47. PMID 14527323 DOI: 10.1146/annurev.biochem.72.121801.161828  1
2003 Ragsdale SW. Pyruvate ferredoxin oxidoreductase and its radical intermediate. Chemical Reviews. 103: 2333-46. PMID 12797832 DOI: 10.1021/cr020423e  1
2003 Singh K, Horng YC, Ragsdale SW. Rapid ligand exchange in the MCRred1 form of methyl-coenzyme M reductase. Journal of the American Chemical Society. 125: 2436-43. PMID 12603131 DOI: 10.1021/ja028525+  1
2003 Seravalli J, Gu W, Tam A, Strauss E, Begley TP, Cramer SP, Ragsdale SW. Functional copper at the acetyl-CoA synthase active site. Proceedings of the National Academy of Sciences of the United States of America. 100: 3689-94. PMID 12589021 DOI: 10.1073/pnas.0436720100  1
2002 Tang Q, Carrington PE, Horng YC, Maroney MJ, Ragsdale SW, Bocian DF. X-ray absorption and resonance Raman studies of methyl-coenzyme M reductase indicating that ligand exchange and macrocycle reduction accompany reductive activation. Journal of the American Chemical Society. 124: 13242-56. PMID 12405853 DOI: 10.1021/ja020314h  1
2002 Doukov TI, Iverson TM, Seravalli J, Ragsdale SW, Drennan CL. A Ni-Fe-Cu center in a bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase. Science (New York, N.Y.). 298: 567-72. PMID 12386327 DOI: 10.1126/science.1075843  1
2002 Furdui C, Ragsdale SW. The roles of coenzyme A in the pyruvate:ferredoxin oxidoreductase reaction mechanism: rate enhancement of electron transfer from a radical intermediate to an iron-sulfur cluster. Biochemistry. 41: 9921-37. PMID 12146957 DOI: 10.1021/bi0257641  1
2002 Seravalli J, Kumar M, Ragsdale SW. Rapid kinetic studies of acetyl-CoA synthesis: evidence supporting the catalytic intermediacy of a paramagnetic NiFeC species in the autotrophic Wood-Ljungdahl pathway. Biochemistry. 41: 1807-19. PMID 11827525 DOI: 10.1021/bi011687i  1
2001 Horng YC, Becker DF, Ragsdale SW. Mechanistic studies of methane biogenesis by methyl-coenzyme M reductase: evidence that coenzyme B participates in cleaving the C-S bond of methyl-coenzyme M. Biochemistry. 40: 12875-85. PMID 11669624 DOI: 10.1021/bi011196y  1
2001 Seravalli J, Brown KL, Ragsdale SW. Acetyl coenzyme A synthesis from unnatural methylated corrinoids: requirement for "base-off" coordination at cobalt. Journal of the American Chemical Society. 123: 1786-7. PMID 11456791 DOI: 10.1021/ja005709k  1
2001 Telser J, Davydov R, Horng YC, Ragsdale SW, Hoffman BM. Cryoreduction of methyl-coenzyme M reductase: EPR characterization of forms, MCR(ox1) and MCR (red1). Journal of the American Chemical Society. 123: 5853-60. PMID 11414817 DOI: 10.1021/ja010428d  1
2001 Murakami E, Deppenmeier U, Ragsdale SW. Characterization of the intramolecular electron transfer pathway from 2-hydroxyphenazine to the heterodisulfide reductase from Methanosarcina thermophila. The Journal of Biological Chemistry. 276: 2432-9. PMID 11034998 DOI: 10.1074/jbc.M004809200  1
2000 Doukov T, Seravalli J, Stezowski JJ, Ragsdale SW. Crystal structure of a methyltetrahydrofolate- and corrinoid-dependent methyltransferase. Structure (London, England : 1993). 8: 817-30. PMID 10997901 DOI: 10.1016/S0969-2126(00)00172-6  1
2000 Seravalli J, Ragsdale SW. Channeling of carbon monoxide during anaerobic carbon dioxide fixation. Biochemistry. 39: 1274-7. PMID 10684606 DOI: 10.1021/bi991812e  1
2000 Murakami E, Ragsdale SW. Evidence for intersubunit communication during acetyl-CoA cleavage by the multienzyme CO dehydrogenase/acetyl-CoA synthase complex from Methanosarcina thermophila. Evidence that the beta subunit catalyzes C-C and C-S bond cleavage. The Journal of Biological Chemistry. 275: 4699-707. PMID 10671500 DOI: 10.1074/jbc.275.7.4699  1
1999 Seravalli J, Shoemaker RK, Sudbeck MJ, Ragsdale SW. Binding of (6R,S)-methyltetrahydrofolate to methyltransferase from Clostridium thermoaceticum: role of protonation of methyltetrahydrofolate in the mechanism of methyl transfer. Biochemistry. 38: 5736-45. PMID 10231524 DOI: 10.1021/bi9824745  1
1999 Seravalli J, Zhao S, Ragsdale SW. Mechanism of transfer of the methyl group from (6S)-methyltetrahydrofolate to the corrinoid/iron-sulfur protein catalyzed by the methyltransferase from Clostridium thermoaceticum: a key step in the Wood-Ljungdahl pathway of acetyl-CoA synthesis. Biochemistry. 38: 5728-35. PMID 10231523 DOI: 10.1021/bi982473c  1
1998 Simianu M, Murakami E, Brewer JM, Ragsdale SW. Purification and properties of the heme- and iron-sulfur-containing heterodisulfide reductase from Methanosarcina thermophila. Biochemistry. 37: 10027-39. PMID 9665708 DOI: 10.1021/bi9726483  1
1998 Bäumer S, Murakami E, Brodersen J, Gottschalk G, Ragsdale SW, Deppenmeier U. The F420H2:heterodisulfide oxidoreductase system from Methanosarcina species. 2-Hydroxyphenazine mediates electron transfer from F420H2 dehydrogenase to heterodisulfide reductase. Febs Letters. 428: 295-8. PMID 9654152 DOI: 10.1016/S0014-5793(98)00555-9  1
1997 Seravalli J, Kumar M, Lu WP, Ragsdale SW. Mechanism of carbon monoxide oxidation by the carbon monoxide dehydrogenase/acetyl-CoA synthase from Clostridium thermoaceticum: kinetic characterization of the intermediates. Biochemistry. 36: 11241-51. PMID 9287167 DOI: 10.1021/bi970590m  1
1996 Ragsdale SW, Kumar M. Nickel-Containing Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase(,). Chemical Reviews. 96: 2515-2540. PMID 11848835  1
1995 Seravalli J, Kumar M, Lu WP, Ragsdale SW. Mechanism of CO oxidation by carbon monoxide dehydrogenase from Clostridium thermoaceticum and its inhibition by anions. Biochemistry. 34: 7879-88. PMID 7794899  1
1995 Lu WP, Becher B, Gottschalk G, Ragsdale SW. Electron paramagnetic resonance spectroscopic and electrochemical characterization of the partially purified N5-methyltetrahydromethanopterin:coenzyme M methyltransferase from Methanosarcina mazei Gö1. Journal of Bacteriology. 177: 2245-50. PMID 7730249  1
1995 Wirt MD, Kumar M, Wu JJ, Scheuring EM, Ragsdale SW, Chance MR. Structural and electronic factors in heterolytic cleavage: formation of the Co(I) intermediate in the corrinoid/iron-sulfur protein from Clostridium thermoaceticum. Biochemistry. 34: 5269-73. PMID 7711048  1
1995 Kumar M, Qiu D, Spiro TG, Ragsdale SW. A methylnickel intermediate in a bimetallic mechanism of acetyl-coenzyme A synthesis by anaerobic bacteria. Science (New York, N.Y.). 270: 628-30. PMID 7570019  1
1994 Qiu D, Kumar M, Ragsdale SW, Spiro TG. Nature's carbonylation catalyst: Raman spectroscopic evidence that carbon monoxide binds to iron, not nickel, in CO dehydrogenase. Science (New York, N.Y.). 264: 817-9. PMID 8171334  1
1994 Clements AP, Kilpatrick L, Lu WP, Ragsdale SW, Ferry JG. Characterization of the iron-sulfur clusters in ferredoxin from acetate-grown Methanosarcina thermophila. Journal of Bacteriology. 176: 2689-93. PMID 8169218  1
1994 Lu WP, Jablonski PE, Rasche M, Ferry JG, Ragsdale SW. Characterization of the metal centers of the Ni/Fe-S component of the carbon-monoxide dehydrogenase enzyme complex from Methanosarcina thermophila. The Journal of Biological Chemistry. 269: 9736-42. PMID 8144565  1
1994 Kumar M, Lu WP, Ragsdale SW. Binding of carbon disulfide to the site of acetyl-CoA synthesis by the nickel-iron-sulfur protein, carbon monoxide dehydrogenase, from Clostridium thermoaceticum. Biochemistry. 33: 9769-77. PMID 8068656  1
1993 Lu WP, Schiau I, Cunningham JR, Ragsdale SW. Sequence and expression of the gene encoding the corrinoid/iron-sulfur protein from Clostridium thermoaceticum and reconstitution of the recombinant protein to full activity. The Journal of Biological Chemistry. 268: 5605-14. PMID 8449924  1
1993 Jablonski PE, Lu WP, Ragsdale SW, Ferry JG. Characterization of the metal centers of the corrinoid/iron-sulfur component of the CO dehydrogenase enzyme complex from Methanosarcina thermophila by EPR spectroscopy and spectroelectrochemistry. The Journal of Biological Chemistry. 268: 325-9. PMID 8380157  1
1992 Roberts JR, Lu WP, Ragsdale SW. Acetyl-coenzyme A synthesis from methyltetrahydrofolate, CO, and coenzyme A by enzymes purified from Clostridium thermoaceticum: attainment of in vivo rates and identification of rate-limiting steps. Journal of Bacteriology. 174: 4667-76. PMID 1624454  1
1991 Lu WP, Ragsdale SW. Reductive activation of the coenzyme A/acetyl-CoA isotopic exchange reaction catalyzed by carbon monoxide dehydrogenase from Clostridium thermoaceticum and its inhibition by nitrous oxide and carbon monoxide. The Journal of Biological Chemistry. 266: 3554-64. PMID 1995618  1
1991 Morton TA, Runquist JA, Ragsdale SW, Shanmugasundaram T, Wood HG, Ljungdahl LG. The primary structure of the subunits of carbon monoxide dehydrogenase/acetyl-CoA synthase from Clostridium thermoaceticum. The Journal of Biological Chemistry. 266: 23824-8. PMID 1748656  1
1990 Lu WP, Harder SR, Ragsdale SW. Controlled potential enzymology of methyl transfer reactions involved in acetyl-CoA synthesis by CO dehydrogenase and the corrinoid/iron-sulfur protein from Clostridium thermoaceticum. The Journal of Biological Chemistry. 265: 3124-33. PMID 2303444  1
1989 Harder SR, Lu WP, Feinberg BA, Ragsdale SW. Spectroelectrochemical studies of the corrinoid/iron-sulfur protein involved in acetyl coenzyme A synthesis by Clostridium thermoaceticum. Biochemistry. 28: 9080-7. PMID 2605242  1
1988 Shanmugasundaram T, Ragsdale SW, Wood HG. Role of carbon monoxide dehydrogenase in acetate synthesis by the acetogenic bacterium, Acetobacterium woodii. Biofactors (Oxford, England). 1: 147-52. PMID 2855585  1
1986 Wood HG, Ragsdale SW, Pezacka E. A new pathway of autotrophic growth utilizing carbon monoxide or carbon dioxide and hydrogen. Biochemistry International. 12: 421-40. PMID 3011003  1
1985 Ragsdale SW, Wood HG, Antholine WE. Evidence that an iron-nickel-carbon complex is formed by reaction of CO with the CO dehydrogenase from Clostridium thermoaceticum. Proceedings of the National Academy of Sciences of the United States of America. 82: 6811-4. PMID 2995986  1
1985 Ragsdale SW, Wood HG. Acetate biosynthesis by acetogenic bacteria. Evidence that carbon monoxide dehydrogenase is the condensing enzyme that catalyzes the final steps of the synthesis. The Journal of Biological Chemistry. 260: 3970-7. PMID 2984190  1
1984 Ragsdale SW, Ljungdahl LG. Characterization of ferredoxin, flavodoxin, and rubredoxin from Clostridium formicoaceticum grown in media with high and low iron contents. Journal of Bacteriology. 157: 1-6. PMID 6690418  1
1984 Ragsdale SW, Ljungdahl LG. Purification and properties of NAD-dependent 5,10-methylenetetrahydrofolate dehydrogenase from Acetobacterium woodii. The Journal of Biological Chemistry. 259: 3499-503. PMID 6608524  1
1984 Ragsdale SW, Ljungdahl LG. Hydrogenase from Acetobacterium woodii. Archives of Microbiology. 139: 361-5. PMID 6393895 DOI: 10.1007/BF00408380  1
1983 Ragsdale SW, Clark JE, Ljungdahl LG, Lundie LL, Drake HL. Properties of purified carbon monoxide dehydrogenase from Clostridium thermoaceticum, a nickel, iron-sulfur protein. The Journal of Biological Chemistry. 258: 2364-9. PMID 6687389  1
1983 Ragsdale SW, Ljungdahl LG, DerVartanian DV. 13C and 61Ni isotope substitutions confirm the presence of a nickel (III)-carbon species in acetogenic CO dehydrogenases. Biochemical and Biophysical Research Communications. 115: 658-65. PMID 6312988 DOI: 10.1016/S0006-291X(83)80195-8  1
1983 Ragsdale SW, Ljungdahl LG, DerVartanian DV. Isolation of carbon monoxide dehydrogenase from Acetobacterium woodii and comparison of its properties with those of the Clostridium thermoaceticum enzyme. Journal of Bacteriology. 155: 1224-37. PMID 6309745  1
1982 Clark JE, Ragsdale SW, Ljungdahl LG, Wiegel J. Levels of enzymes involved in the synthesis of acetate from CO2 in Clostridium thermoautotrophicum. Journal of Bacteriology. 151: 507-9. PMID 6806250  1
1982 Ragsdale SW, Ljungdahl LG, DerVartanian DV. EPR evidence for nickel-substrate interaction in carbon monoxide dehydrogenase from Clostridium thermoaceticum. Biochemical and Biophysical Research Communications. 108: 658-63. PMID 6293499 DOI: 10.1016/0006-291X(82)90880-4  1
Show low-probability matches.