Luis Quadri - Publications

Affiliations: 
Weill Cornell Medical College, New York, NY, United States 
Area:
Microbiology Biology, Biochemistry

28/40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Vergnolle O, Chavadi SS, Edupuganti UR, Mohandas P, Chan C, Zeng J, Kopylov M, Angelo NG, Warren JD, Soll CE, Quadri LE. Biosynthesis of cell envelope-associated phenolic glycolipids in Mycobacterium marinum. Journal of Bacteriology. 197: 1040-50. PMID 25561717 DOI: 10.1128/JB.02546-14  0.52
2014 D'Erasmo MP, Smith WB, Munoz A, Mohandas P, Au AS, Marineau JJ, Quadri LE, Bradner JE, Murelli RP. 7,9-Diaryl-1,6,8-trioxaspiro[4.5]dec-3-en-2-ones: readily accessible and highly potent anticancer compounds. Bioorganic & Medicinal Chemistry Letters. 24: 4035-8. PMID 25011911 DOI: 10.1016/j.bmcl.2014.05.102  0.52
2013 Lun S, Guo H, Adamson J, Cisar JS, Davis TD, Chavadi SS, Warren JD, Quadri LE, Tan DS, Bishai WR. Pharmacokinetic and in vivo efficacy studies of the mycobactin biosynthesis inhibitor salicyl-AMS in mice. Antimicrobial Agents and Chemotherapy. 57: 5138-40. PMID 23856770 DOI: 10.1128/AAC.00918-13  0.52
2012 Tatham E, Sundaram Chavadi S, Mohandas P, Edupuganti UR, Angala SK, Chatterjee D, Quadri LE. Production of mycobacterial cell wall glycopeptidolipids requires a member of the MbtH-like protein family. Bmc Microbiology. 12: 118. PMID 22726990 DOI: 10.1186/1471-2180-12-118  0.52
2012 Chavadi SS, Onwueme KC, Edupuganti UR, Jerome J, Chatterjee D, Soll CE, Quadri LE. The mycobacterial acyltransferase PapA5 is required for biosynthesis of cell wall-associated phenolic glycolipids. Microbiology (Reading, England). 158: 1379-87. PMID 22361940 DOI: 10.1099/mic.0.057869-0  0.52
2011 Ferreras JA, Gupta A, Amin ND, Basu A, Sinha BN, Worgall S, Jayaprakash V, Quadri LE. Chemical scaffolds with structural similarities to siderophores of nonribosomal peptide-polyketide origin as novel antimicrobials against Mycobacterium tuberculosis and Yersinia pestis. Bioorganic & Medicinal Chemistry Letters. 21: 6533-7. PMID 21940166 DOI: 10.1016/j.bmcl.2011.08.052  0.52
2011 Chavadi SS, Stirrett KL, Edupuganti UR, Vergnolle O, Sadhanandan G, Marchiano E, Martin C, Qiu WG, Soll CE, Quadri LEN. Mutational and phylogenetic analyses of the mycobacterial mbt gene cluster Journal of Bacteriology. 193: 5905-5913. PMID 21873494 DOI: 10.1128/JB.05811-11  0.52
2011 Chavadi SS, Edupuganti UR, Vergnolle O, Fatima I, Singh SM, Soll CE, Quadri LE. Inactivation of tesA reduces cell wall lipid production and increases drug susceptibility in mycobacteria. The Journal of Biological Chemistry. 286: 24616-25. PMID 21592957 DOI: 10.1074/jbc.M111.247601  0.32
2009 He W, Soll CE, Chavadi SS, Zhang G, Warren JD, Quadri LE. Cooperation between a coenzyme A-independent stand-alone initiation module and an iterative type I polyketide synthase during synthesis of mycobacterial phenolic glycolipids. Journal of the American Chemical Society. 131: 16744-50. PMID 19799378 DOI: 10.1021/ja904792q  0.52
2009 Xu Y, Tertilt C, Krause A, Quadri LE, Crystal RG, Worgall S. Influence of the cystic fibrosis transmembrane conductance regulator on expression of lipid metabolism-related genes in dendritic cells. Respiratory Research. 10: 26. PMID 19344509 DOI: 10.1186/1465-9921-10-26  0.52
2008 Stirrett KL, Ferreras JA, Rossi SM, Moy RL, Fonseca FV, Quadri LE. A multicopy suppressor screening approach as a means to identify antibiotic resistance determinant candidates in Yersinia pestis. Bmc Microbiology. 8: 122. PMID 18644132 DOI: 10.1186/1471-2180-8-122  0.52
2008 Stirrett KL, Ferreras JA, Jayaprakash V, Sinha BN, Ren T, Quadri LE. Small molecules with structural similarities to siderophores as novel antimicrobials against Mycobacterium tuberculosis and Yersinia pestis. Bioorganic & Medicinal Chemistry Letters. 18: 2662-8. PMID 18394884 DOI: 10.1016/j.bmcl.2008.03.025  0.52
2008 Ferreras JA, Stirrett KL, Lu X, Ryu JS, Soll CE, Tan DS, Quadri LE. Mycobacterial phenolic glycolipid virulence factor biosynthesis: mechanism and small-molecule inhibition of polyketide chain initiation. Chemistry & Biology. 15: 51-61. PMID 18158259 DOI: 10.1016/j.chembiol.2007.11.010  0.52
2007 Cisar JS, Ferreras JA, Soni RK, Quadri LE, Tan DS. Exploiting ligand conformation in selective inhibition of non-ribosomal peptide synthetase amino acid adenylation with designed macrocyclic small molecules. Journal of the American Chemical Society. 129: 7752-3. PMID 17542590 DOI: 10.1021/ja0721521  0.52
2005 Ferreras JA, Ryu JS, Di Lello F, Tan DS, Quadri LE. Small-molecule inhibition of siderophore biosynthesis in Mycobacterium tuberculosis and Yersinia pestis. Nature Chemical Biology. 1: 29-32. PMID 16407990 DOI: 10.1038/nchembio706  0.52
2005 Onwueme KC, Vos CJ, Zurita J, Ferreras JA, Quadri LE. The dimycocerosate ester polyketide virulence factors of mycobacteria. Progress in Lipid Research. 44: 259-302. PMID 16115688 DOI: 10.1016/j.plipres.2005.07.001  0.52
2005 Worgall S, Heguy A, Luettich K, O'Connor TP, Harvey BG, Quadri LE, Crystal RG. Similarity of gene expression patterns in human alveolar macrophages in response to Pseudomonas aeruginosa and Burkholderia cepacia. Infection and Immunity. 73: 5262-8. PMID 16041053 DOI: 10.1128/IAI.73.8.5262-5268.2005  0.52
2005 Onwueme KC, Vos CJ, Zurita J, Soll CE, Quadri LE. Identification of phthiodiolone ketoreductase, an enzyme required for production of mycobacterial diacyl phthiocerol virulence factors. Journal of Bacteriology. 187: 4760-6. PMID 15995190 DOI: 10.1128/JB.187.14.4760-4766.2005  0.52
2005 Palma M, Zurita J, Ferreras JA, Worgall S, Larone DH, Shi L, Campagne F, Quadri LE. Pseudomonas aeruginosa SoxR does not conform to the archetypal paradigm for SoxR-dependent regulation of the bacterial oxidative stress adaptive response. Infection and Immunity. 73: 2958-66. PMID 15845502 DOI: 10.1128/IAI.73.5.2958-2966.2005  0.52
2004 Buglino J, Onwueme KC, Ferreras JA, Quadri LE, Lima CD. Crystal structure of PapA5, a phthiocerol dimycocerosyl transferase from Mycobacterium tuberculosis. The Journal of Biological Chemistry. 279: 30634-42. PMID 15123643 DOI: 10.1074/jbc.M404011200  0.52
2004 Onwueme KC, Ferreras JA, Buglino J, Lima CD, Quadri LE. Mycobacterial polyketide-associated proteins are acyltransferases: proof of principle with Mycobacterium tuberculosis PapA5. Proceedings of the National Academy of Sciences of the United States of America. 101: 4608-13. PMID 15070765 DOI: 10.1073/pnas.0306928101  0.52
2004 Palma M, DeLuca D, Worgall S, Quadri LE. Transcriptome analysis of the response of Pseudomonas aeruginosa to hydrogen peroxide. Journal of Bacteriology. 186: 248-52. PMID 14679246 DOI: 10.1128/JB.186.1.248-252.2004  0.52
2003 Palma M, Worgall S, Quadri LE. Transcriptome analysis of the Pseudomonas aeruginosa response to iron. Archives of Microbiology. 180: 374-9. PMID 14513207 DOI: 10.1007/s00203-003-0602-z  0.52
1999 Quadri LE, Keating TA, Patel HM, Walsh CT. Assembly of the Pseudomonas aeruginosa nonribosomal peptide siderophore pyochelin: In vitro reconstitution of aryl-4, 2-bisthiazoline synthetase activity from PchD, PchE, and PchF. Biochemistry. 38: 14941-54. PMID 10555976 DOI: 10.1021/bi991787c  0.52
1998 Quadri LEN, Sello J, Keating TA, Weinreb PH, Walsh CT. Identification of a Mycobacterium tuberculosis gene cluster encoding the biosynthetic enzymes for assembly of the virulence-conferring siderophore mycobactin Chemistry and Biology. 5: 631-645. PMID 9831524 DOI: 10.1016/S1074-5521(98)90291-5  0.52
1998 Quadri LEN, Weinreb PH, Lei M, Nakano MM, Zuber P, Walsh CT. Characterization of Sfp, a Bacillus subtilis phosphopantetheinyl transferase for peptidyl carder protein domains in peptide synthetases Biochemistry. 37: 1585-1595. PMID 9484229 DOI: 10.1021/bi9719861  0.52
1998 Weinreb PH, Quadri LEN, Walsh CT, Zuber P. Stoichiometry and specificity of in vitro phosphopantetheinylation and aminoacylation of the valine-activating module of surfactin synthetase Biochemistry. 37: 1575-1584. PMID 9484228 DOI: 10.1021/bi9719859  0.52
1997 Walsh CT, Gehring AM, Weinreb PH, Quadri LE, Flugel RS. Post-translational modification of polyketide and nonribosomal peptide synthases. Current Opinion in Chemical Biology. 1: 309-15. PMID 9667867  0.52
Low-probability matches
2018 Bythrow GV, Mohandas P, Guney T, Standke LC, Germain GA, Lu X, Ji C, Levendosky K, Chavadi SS, Tan DS, Quadri LEN. Kinetic Analyses of the Siderophore Biosynthesis Inhibitor Salicyl-AMS and Analogues as MbtA Inhibitors and Antimycobacterial Agents. Biochemistry. PMID 30582694 DOI: 10.1021/acs.biochem.8b01153  0.2
2016 Davis TD, Mohandas P, Chiriac MI, Bythrow GV, Quadri LE, Tan DS. Design, synthesis, and biological evaluation of α-hydroxyacyl-AMS inhibitors of amino acid adenylation enzymes. Bioorganic & Medicinal Chemistry Letters. PMID 27692545 DOI: 10.1016/j.bmcl.2016.09.027  0.2
2016 Mohandas P, Budell WC, Mueller E, Au A, Bythrow GV, Quadri LE. Pleiotropic consequences of gene knockouts in the phthiocerol dimycocerosate and phenolic glycolipid biosynthetic gene cluster of the opportunistic human pathogen Mycobacterium marinum. Fems Microbiology Letters. PMID 26818253 DOI: 10.1093/femsle/fnw016  0.08
2020 Budell WC, Germain GA, Janisch N, McKie-Krisberg Z, Jayaprakash AD, Resnick AE, Quadri LEN. Transposon mutagenesis in Mycobacterium kansasii links a small RNA gene to colony morphology and biofilm formation and identifies 9,885 intragenic insertions that do not compromise colony outgrowth. Microbiologyopen. e988. PMID 32083796 DOI: 10.1002/mbo3.988  0.01
2017 Swarbrick CM, Bythrow GV, Aragão DG, Germain GA, Quadri LE, Forwood JK. Mycobacteria encode active and inactive classes of TesB fatty-acyl CoA thioesterases revealed through structural and functional analysis. Biochemistry. PMID 28156101 DOI: 10.1021/acs.biochem.6b01049  0.01
2014 Quadri LE. Biosynthesis of mycobacterial lipids by polyketide synthases and beyond. Critical Reviews in Biochemistry and Molecular Biology. 49: 179-211. PMID 24625105 DOI: 10.3109/10409238.2014.896859  0.01
2007 Quadri LE. Strategic paradigm shifts in the antimicrobial drug discovery process of the 21st century. Infectious Disorders Drug Targets. 7: 230-7. PMID 17897059  0.01
2006 Rohde BH, Quadri LE. Functional characterization of a three-component regulatory system involved in quorum sensing-based regulation of peptide antibiotic production in Carnobacterium maltaromaticum. Bmc Microbiology. 6: 93. PMID 17054797 DOI: 10.1186/1471-2180-6-93  0.01
2002 Quadri LE. Regulation of antimicrobial peptide production by autoinducer-mediated quorum sensing in lactic acid bacteria. Antonie Van Leeuwenhoek. 82: 133-45. PMID 12369185  0.01
2001 Kleerebezem M, Kuipers OP, de Vos WM, Stiles ME, Quadri LE. A two-component signal-transduction cascade in Carnobacterium piscicola LV17B: two signaling peptides and one sensor-transmitter. Peptides. 22: 1597-601. PMID 11587787 DOI: 10.1016/S0196-9781(01)00494-6  0.01
2001 Kleerebezem M, Quadri LE. Peptide pheromone-dependent regulation of antimicrobial peptide production in Gram-positive bacteria: a case of multicellular behavior. Peptides. 22: 1579-96. PMID 11587786 DOI: 10.1016/S0196-9781(01)00493-4  0.01
2000 Quadri LE. Assembly of aryl-capped siderophores by modular peptide synthetases and polyketide synthases. Molecular Microbiology. 37: 1-12. PMID 10931301 DOI: 10.1046/j.1365-2958.2000.01941.x  0.01
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