Eric B. Kmiec - Publications

University of Delaware, Newark, DE, United States 
Molecular Biology, Biochemistry

32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Bonner M, Strouse B, Applegate M, Livingston P, Kmiec EB. DNA damage response pathway and replication fork stress during oligonucleotide directed gene editing. Molecular Therapy. Nucleic Acids. 1: e18. PMID 23343929 DOI: 10.1038/mtna.2012.9  1
2012 Livingston P, Strouse B, Perry H, Borjigin M, Bialk P, Kmiec EB. Oligonucleotide delivery by nucleofection does not rescue the reduced proliferation phenotype of gene-edited cells. Nucleic Acid Therapeutics. 22: 405-13. PMID 23072627 DOI: 10.1089/nat.2012.0374  1
2011 Falgowski KA, Kmiec EB. Gene editing activity on extrachromosomal arrays in C. elegans transgenics. Gene. 475: 87-93. PMID 21241788 DOI: 10.1016/j.gene.2010.12.014  1
2009 Bonner M, Kmiec EB. DNA breakage associated with targeted gene alteration directed by DNA oligonucleotides. Mutation Research. 669: 85-94. PMID 19463835 DOI: 10.1016/j.mrfmmm.2009.05.004  1
2009 Engstrom JU, Suzuki T, Kmiec EB. Regulation of targeted gene repair by intrinsic cellular processes. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 31: 159-68. PMID 19204988 DOI: 10.1002/bies.200800119  1
2009 Illuzzi J, Yerkes S, Parekh-Olmedo H, Kmiec EB. DNA breakage and induction of DNA damage response proteins precede the appearance of visible mutant huntingtin aggregates. Journal of Neuroscience Research. 87: 733-47. PMID 18831068 DOI: 10.1002/jnr.21881  0.6
2008 Engstrom JU, Kmiec EB. DNA replication, cell cycle progression and the targeted gene repair reaction. Cell Cycle (Georgetown, Tex.). 7: 1402-14. PMID 18424915  1
2008 Schwartz TR, Vasta CA, Bauer TL, Parekh-Olmedo H, Kmiec EB. G-rich oligonucleotides alter cell cycle progression and induce apoptosis specifically in OE19 esophageal tumor cells. Oligonucleotides. 18: 51-63. PMID 18321162 DOI: 10.1089/oli.2007.0109  1
2008 DiMatteo D, Callahan S, Kmiec EB. Genetic conversion of an SMN2 gene to SMN1: a novel approach to the treatment of spinal muscular atrophy. Experimental Cell Research. 314: 878-86. PMID 18078930 DOI: 10.1016/j.yexcr.2007.10.012  1
2007 Ferrara L, Engstrom JU, Schwartz T, Parekh-Olmedo H, Kmiec EB. Recovery of cell cycle delay following targeted gene repair by oligonucleotides. Dna Repair. 6: 1529-35. PMID 17560837 DOI: 10.1016/j.dnarep.2007.04.007  1
2007 Engstrom JU, Kmiec EB. Manipulation of cell cycle progression can counteract the apparent loss of correction frequency following oligonucleotide-directed gene repair. Bmc Molecular Biology. 8: 9. PMID 17284323 DOI: 10.1186/1471-2199-8-9  1
2007 Schwartz TR, Kmiec EB. Reduction of gene repair by selenomethionine with the use of single-stranded oligonucleotides. Bmc Molecular Biology. 8: 7. PMID 17257432 DOI: 10.1186/1471-2199-8-7  0.96
2007 Maguire KK, Kmiec EB. Multiple roles for MSH2 in the repair of a deletion mutation directed by modified single-stranded oligonucleotides. Gene. 386: 107-14. PMID 17113727 DOI: 10.1016/j.gene.2006.08.014  1
2005 Hu Y, Parekh-Olmedo H, Drury M, Skogen M, Kmiec EB. Reaction parameters of targeted gene repair in mammalian cells. Molecular Biotechnology. 29: 197-210. PMID 15767697 DOI: 10.1385/MB:29:3:197  0.6
2005 Brachman EE, Kmiec EB. Gene repair in mammalian cells is stimulated by the elongation of S phase and transient stalling of replication forks. Dna Repair. 4: 445-57. PMID 15725625 DOI: 10.1016/j.dnarep.2004.11.007  1
2004 Parekh-Olmedo H, Wang J, Gusella JF, Kmiec EB. Modified single-stranded oligonucleotides inhibit aggregate formation and toxicity induced by expanded polyglutamine. Journal of Molecular Neuroscience : Mn. 24: 257-67. PMID 15456939 DOI: 10.1385/JMN:24:2:257  1
2004 Ferrara L, Parekh-Olmedo H, Kmiec EB. Enhanced oligonucleotide-directed gene targeting in mammalian cells following treatment with DNA damaging agents. Experimental Cell Research. 300: 170-9. PMID 15383324 DOI: 10.1016/j.yexcr.2004.06.021  0.6
2004 Brachman EE, Kmiec EB. DNA replication and transcription direct a DNA strand bias in the process of targeted gene repair in mammalian cells. Journal of Cell Science. 117: 3867-74. PMID 15265980 DOI: 10.1242/jcs.01250  1
2004 Liu L, Maguire KK, Kmiec EB. Genetic re-engineering of Saccharomyces cerevisiae RAD51 leads to a significant increase in the frequency of gene repair in vivo. Nucleic Acids Research. 32: 2093-101. PMID 15087488 DOI: 10.1093/nar/gkh506  1
2004 Maguire KK, Kmiec EB. Enhancement of in vivo targeted nucleotide exchange by nonspecific carrier DNA. Methods in Molecular Biology (Clifton, N.J.). 262: 209-19. PMID 14769964 DOI: 10.1385/1-59259-761-0:209  1
2003 Parekh-Olmedo H, Engstrom JU, Kmiec EB. The effect of hydroxyurea and trichostatin a on targeted nucleotide exchange in yeast and Mammalian cells. Annals of the New York Academy of Sciences. 1002: 43-55. PMID 14751821  1
2003 Hu Y, Liu L, Kmiec EB. Reduction of Htt inclusion formation in strains of Saccharomyces cerevisiae deficient in certain DNA repair functions: a statistical analysis of phenotype. Experimental Cell Research. 291: 46-55. PMID 14597407  0.48
2003 Liu L, Usher M, Hu Y, Kmiec EB. Nuclease activity of Saccharomyces cerevisiae Mre11 functions in targeted nucleotide alteration. Applied and Environmental Microbiology. 69: 6216-24. PMID 14532083  0.48
2003 Parekh-Olmedo H, Kmiec EB. Targeted nucleotide exchange in the CAG repeat region of the human HD gene. Biochemical and Biophysical Research Communications. 310: 660-6. PMID 14521962  0.6
2003 Liu L, Parekh-Olmedo H, Kmiec EB. The development and regulation of gene repair. Nature Reviews. Genetics. 4: 679-89. PMID 12951569 DOI: 10.1038/nrg1156  0.6
2003 Brachman EE, Kmiec EB. Targeted nucleotide repair of cyc1 mutations in Saccharomyces cerevisiae directed by modified single-stranded DNA oligonucleotides. Genetics. 163: 527-38. PMID 12618392  1
2003 Gamper HB, Nulf CJ, Corey DR, Kmiec EB. The synaptic complex of RecA protein participates in hybridization and inverse strand exchange reactions. Biochemistry. 42: 2643-55. PMID 12614159 DOI: 10.1021/bi0205202  1
2002 Parekh-Olmedo H, Drury M, Kmiec EB. Targeted nucleotide exchange in Saccharomyces cerevisiae directed by short oligonucleotides containing locked nucleic acids. Chemistry & Biology. 9: 1073-84. PMID 12401492  0.6
2002 Liu L, Cheng S, van Brabant AJ, Kmiec EB. Rad51p and Rad54p, but not Rad52p, elevate gene repair in Saccharomyces cerevisiae directed by modified single-stranded oligonucleotide vectors. Nucleic Acids Research. 30: 2742-50. PMID 12087156  0.48
2002 Brachman EE, Kmiec EB. The 'biased' evolution of targeted gene repair. Current Opinion in Molecular Therapeutics. 4: 171-6. PMID 12044039  1
2002 Liu L, Rice MC, Drury M, Cheng S, Gamper H, Kmiec EB. Strand bias in targeted gene repair is influenced by transcriptional activity. Molecular and Cellular Biology. 22: 3852-63. PMID 11997519  0.48
2002 Parekh-Olmedo H, Krainc D, Kmiec EB. Targeted gene repair and its application to neurodegenerative disorders. Neuron. 33: 495-8. PMID 11856524  0.6
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