Tohru Kozasa - Publications

Affiliations: 
University of Illinois at Chicago, Health Sciences Center 
Area:
Pharmacology, Biochemistry

21/103 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Patel M, Kawano T, Suzuki N, Hamakubo T, Karginov AV, Kozasa T. Gα13/PDZ-RhoGEF/RhoA signaling is essential for gastrin-releasing peptide receptor-mediated colon cancer cell migration. Molecular Pharmacology. 86: 252-62. PMID 24958816 DOI: 10.1124/Mol.114.093914  0.6
2014 Rusu L, Andreeva A, Visintine DJ, Kim K, Vogel SM, Stojanovic-Terpo A, Chernaya O, Liu G, Bakhshi FR, Haberichter SL, Iwanari H, Kusano-Arai O, Suzuki N, Hamakubo T, Kozasa T, et al. G protein-dependent basal and evoked endothelial cell vWF secretion. Blood. 123: 442-50. PMID 24081657 DOI: 10.1182/Blood-2013-03-489351  0.6
2013 Gan X, Wang C, Patel M, Kreutz B, Zhou M, Kozasa T, Wu D. Different Raf protein kinases mediate different signaling pathways to stimulate E3 ligase RFFL gene expression in cell migration regulation. The Journal of Biological Chemistry. 288: 33978-84. PMID 24114843 DOI: 10.1074/Jbc.M113.477406  0.48
2013 Chow CR, Suzuki N, Kawamura T, Hamakubo T, Kozasa T. Modification of p115RhoGEF Ser(330) regulates its RhoGEF activity. Cellular Signalling. 25: 2085-92. PMID 23816534 DOI: 10.1016/J.Cellsig.2013.06.012  0.6
2013 Nance MR, Kreutz B, Tesmer VM, Sterne-Marr R, Kozasa T, Tesmer JJ. Structural and functional analysis of the regulator of G protein signaling 2-gαq complex. Structure (London, England : 1993). 21: 438-48. PMID 23434405 DOI: 10.1016/J.Str.2012.12.016  0.48
2011 Kozasa T, Hajicek N, Chow CR, Suzuki N. Signalling mechanisms of RhoGTPase regulation by the heterotrimeric G proteins G12 and G13. Journal of Biochemistry. 150: 357-69. PMID 21873336 DOI: 10.1093/Jb/Mvr105  1
2011 Hajicek N, Kukimoto-Niino M, Mishima-Tsumagari C, Chow CR, Shirouzu M, Terada T, Patel M, Yokoyama S, Kozasa T. Identification of critical residues in G(alpha)13 for stimulation of p115RhoGEF activity and the structure of the G(alpha)13-p115RhoGEF regulator of G protein signaling homology (RH) domain complex. The Journal of Biological Chemistry. 286: 20625-36. PMID 21507947 DOI: 10.1074/Jbc.M110.201392  1
2010 Jernigan KK, Cselenyi CS, Thorne CA, Hanson AJ, Tahinci E, Hajicek N, Oldham WM, Lee LA, Hamm HE, Hepler JR, Kozasa T, Linder ME, Lee E. Gbetagamma activates GSK3 to promote LRP6-mediated beta-catenin transcriptional activity. Science Signaling. 3: ra37. PMID 20460648 DOI: 10.1126/Scisignal.2000647  1
2009 Suzuki N, Hajicek N, Kozasa T. Regulation and physiological functions of G12/13-mediated signaling pathways. Neuro-Signals. 17: 55-70. PMID 19212140 DOI: 10.1159/000186690  1
2009 Suzuki N, Tsumoto K, Hajicek N, Daigo K, Tokita R, Minami S, Kodama T, Hamakubo T, Kozasa T. Activation of leukemia-associated RhoGEF by Galpha13 with significant conformational rearrangements in the interface. The Journal of Biological Chemistry. 284: 5000-9. PMID 19074425 DOI: 10.1074/Jbc.M804073200  1
2008 Masuho I, Mototani Y, Sahara Y, Asami J, Nakamura S, Kozasa T, Inoue T. Dynamic expression patterns of G protein-regulated inducer of neurite outgrowth 1 (GRIN1) and its colocalization with Galphao implicate significant roles of Galphao-GRIN1 signaling in nervous system. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 2415-29. PMID 18729205 DOI: 10.1002/Dvdy.21686  0.48
2008 Hajicek N, Kozasa T. G protein alpha 13 Afcs-Nature Molecule Pages. DOI: 10.1038/Mp.A000029.01  1
2007 Kreutz B, Hajicek N, Yau DM, Nakamura S, Kozasa T. Distinct regions of Galpha13 participate in its regulatory interactions with RGS homology domain-containing RhoGEFs. Cellular Signalling. 19: 1681-9. PMID 17449226 DOI: 10.1016/J.Cellsig.2007.03.004  1
2006 Kreutz B, Yau DM, Nance MR, Tanabe S, Tesmer JJ, Kozasa T. A new approach to producing functional G alpha subunits yields the activated and deactivated structures of G alpha(12/13) proteins. Biochemistry. 45: 167-74. PMID 16388592 DOI: 10.1021/Bi051729T  0.48
2004 Tanabe S, Kreutz B, Suzuki N, Kozasa T. Regulation of RGS-RhoGEFs by Galpha12 and Galpha13 proteins. Methods in Enzymology. 390: 285-94. PMID 15488184 DOI: 10.1016/S0076-6879(04)90018-3  0.6
2004 Nakamura S, Kreutz B, Tanabe S, Suzuki N, Kozasa T. Critical role of lysine 204 in switch I region of Galpha13 for regulation of p115RhoGEF and leukemia-associated RhoGEF. Molecular Pharmacology. 66: 1029-34. PMID 15258251 DOI: 10.1124/Mol.104.002287  0.6
2003 Yau DM, Yokoyama N, Goshima Y, Siddiqui ZK, Siddiqui SS, Kozasa T. Identification and molecular characterization of the G alpha12-Rho guanine nucleotide exchange factor pathway in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 100: 14748-53. PMID 14657363 DOI: 10.1073/Pnas.2533143100  0.48
2003 Johnson EN, Seasholtz TM, Waheed AA, Kreutz B, Suzuki N, Kozasa T, Jones TL, Brown JH, Druey KM. RGS16 inhibits signalling through the G alpha 13-Rho axis. Nature Cell Biology. 5: 1095-103. PMID 14634662 DOI: 10.1038/Ncb1065  0.6
2003 Suzuki N, Nakamura S, Mano H, Kozasa T. Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF. Proceedings of the National Academy of Sciences of the United States of America. 100: 733-8. PMID 12515866 DOI: 10.1073/Pnas.0234057100  0.6
2001 Niu J, Vaiskunaite R, Suzuki N, Kozasa T, Carr DW, Dulin N, Voyno-Yasenetskaya TA. Interaction of heterotrimeric G13 protein with an A-kinase-anchoring protein 110 (AKAP110) mediates cAMP-independent PKA activation. Current Biology : Cb. 11: 1686-90. PMID 11696326 DOI: 10.1016/S0960-9822(01)00530-9  0.6
1993 Kabir AM, Kozasa T, Kaziro Y, Nakamura S. A mutant substituting valine for glycine at position 49 of Gs alpha induces neuronal differentiation of PC12 cells without activation of adenylate cyclase. Cellular Signalling. 5: 443-52. PMID 8396962 DOI: 10.1016/0898-6568(93)90084-Y  0.48
Low-probability matches
2008 Zhang Y, Chen YH, Bangaru SD, He L, Abele K, Tanabe S, Kozasa T, Yang J. Origin of the voltage dependence of G-protein regulation of P/Q-type Ca2+ channels Journal of Neuroscience. 28: 14176-14188. PMID 19109500 DOI: 10.1523/Jneurosci.1350-08.2008  0.24
2005 Nishida M, Tanabe S, Maruyama Y, Mangmool S, Urayama K, Nagamatsu Y, Takagahara S, Turner JH, Kozasa T, Kobayashi H, Sato Y, Kawanishi T, Inoue R, Nagao T, Kurose H. G alpha 12/13- and reactive oxygen species-dependent activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase by angiotensin receptor stimulation in rat neonatal cardiomyocytes. The Journal of Biological Chemistry. 280: 18434-41. PMID 15743761 DOI: 10.1074/Jbc.M409710200  0.24
2003 Arai K, Maruyama Y, Nishida M, Tanabe S, Takagahara S, Kozasa T, Mori Y, Nagao T, Kurose H. Differential requirement of G alpha12, G alpha13, G alphaq, and G beta gamma for endothelin-1-induced c-Jun NH2-terminal kinase and extracellular signal-regulated kinase activation. Molecular Pharmacology. 63: 478-88. PMID 12606754 DOI: 10.1124/Mol.63.3.478  0.24
2002 Maruyama Y, Nishida M, Sugimoto Y, Tanabe S, Turner JH, Kozasa T, Wada T, Nagao T, Kurose H. Galpha(12/13) mediates alpha(1)-adrenergic receptor-induced cardiac hypertrophy. Circulation Research. 91: 961-9. PMID 12433842 DOI: 10.1161/01.RES.0000043282.39776.7C  0.24
2007 Huang JS, Dong L, Kozasa T, Le Breton GC. Signaling through G(alpha)13 switch region I is essential for protease-activated receptor 1-mediated human platelet shape change, aggregation, and secretion. The Journal of Biological Chemistry. 282: 10210-22. PMID 17298951 DOI: 10.1074/Jbc.M605678200  0.2
2006 Zhao Q, Albsoul-Younes AM, Zhao P, Kozasa T, Nakajima Y, Nakajima S. Dominant negative effects of a Gbeta mutant on G-protein coupled inward rectifier K+ channel. Febs Letters. 580: 3879-82. PMID 16797547 DOI: 10.1016/J.Febslet.2006.06.016  0.2
2006 Marty C, Kozasa T, Quinn MT, Ye RD. Activation state-dependent interaction between Galphai and p67phox. Molecular and Cellular Biology. 26: 5190-200. PMID 16782902 DOI: 10.1128/Mcb.01979-05  0.2
2004 Wang Q, Liu M, Kozasa T, Rothestein JD, Sternweis PC, Neubig RR. Ribozyme- and siRNA-mediated suppression of RGS-containing RhoGEF proteins. Methods in Enzymology. 389: 244-65. PMID 15313570 DOI: 10.1016/S0076-6879(04)89015-3  0.2
2004 Wang Q, Liu M, Kozasa T, Rothstein JD, Sternweis PC, Neubig RR. Thrombin and lysophosphatidic acid receptors utilize distinct rhoGEFs in prostate cancer cells. The Journal of Biological Chemistry. 279: 28831-4. PMID 15143072 DOI: 10.1074/Jbc.C400105200  0.2
2004 Kozasa T, Ye RD. Selective inhibition of G protein-mediated pathways using RGS domains. Methods in Molecular Biology (Clifton, N.J.). 237: 153-67. PMID 14501048 DOI: 10.1385/1-59259-430-1:153  0.2
2002 Wells CD, Liu MY, Jackson M, Gutowski S, Sternweis PM, Rothstein JD, Kozasa T, Sternweis PC. Mechanisms for reversible regulation between G13 and Rho exchange factors. The Journal of Biological Chemistry. 277: 1174-81. PMID 11698392 DOI: 10.1074/Jbc.M105274200  0.2
2001 Albsoul-Younes AM, Sternweis PM, Zhao P, Nakata H, Nakajima S, Nakajima Y, Kozasa T. Interaction Sites of the G Protein β Subunit with Brain G Protein-coupled Inward Rectifier K+ Channel Journal of Biological Chemistry. 276: 12712-12717. PMID 11278861 DOI: 10.1074/Jbc.M011231200  0.2
1999 Carman CV, Parent JL, Day PW, Pronin AN, Sternweis PM, Wedegaertner PB, Gilman AG, Benovic JL, Kozasa T. Selective regulation of Galpha(q/11) by an RGS domain in the G protein-coupled receptor kinase, GRK2. The Journal of Biological Chemistry. 274: 34483-92. PMID 10567430 DOI: 10.1074/Jbc.274.48.34483  0.2
1999 Chen LT, Gilman AG, Kozasa T. A candidate target for G protein action in brain Journal of Biological Chemistry. 274: 26931-26938. PMID 10480904 DOI: 10.1074/Jbc.274.38.26931  0.2
1998 Panchenko MP, Saxena K, Li Y, Charnecki S, Sternweis PM, Smith TF, Gilman AG, Kozasa T, Neer EJ. Sites important for PLCbeta2 activation by the G protein betagamma subunit map to the sides of the beta propeller structure. The Journal of Biological Chemistry. 273: 28298-304. PMID 9774453 DOI: 10.1074/Jbc.273.43.28298  0.2
1998 Wang J, Ducret A, Tu Y, Kozasa T, Aebersold R, Ross EM. RGSZ1, a Gz-selective RGS protein in brain. Structure, membrane association, regulation by Galphaz phosphorylation, and relationship to a Gz gtpase-activating protein subfamily. The Journal of Biological Chemistry. 273: 26014-25. PMID 9748280 DOI: 10.1074/Jbc.273.40.26014  0.2
1998 Hart MJ, Jiang X, Kozasa T, Roscoe W, Singer WD, Gilman AG, Sternweis PC, Bollag G. Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13. Science (New York, N.Y.). 280: 2112-4. PMID 9641916 DOI: 10.1126/Science.280.5372.2112  0.2
1998 Kozasa T, Jiang X, Hart MJ, Sternweis PM, Singer WD, Gilman AG, Bollag G, Sternweis PC. p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13. Science (New York, N.Y.). 280: 2109-11. PMID 9641915 DOI: 10.1126/Science.280.5372.2109  0.2
1998 Li Y, Sternweis PM, Charneckit S, Smith TF, Gilman AG, Neer EJ, Kozasa T. Sites for Gα binding on the G protein β subunit overlap with sites for regulation of phospholipase Cβ and adenyly cyclase Journal of Biological Chemistry. 273: 16265-16272. PMID 9632686 DOI: 10.1074/Jbc.273.26.16265  0.2
1998 Hsin Chieh Lin, Duncan JA, Kozasa T, Gilman AG. Sequestration of the G protein βγ subunit complex inhibits receptor- mediated endocytosis Proceedings of the National Academy of Sciences of the United States of America. 95: 5057-5060. PMID 9560227 DOI: 10.1073/Pnas.95.9.5057  0.2
1997 Takano K, Yasufuku-Takano J, Kozasa T, Nakajima S, Nakajima Y. Different G proteins mediate somatostatin-induced inward rectifier K+ currents in murine brain and endocrine cells Journal of Physiology. 502: 559-567. PMID 9279808 DOI: 10.1111/J.1469-7793.1997.559Bj.X  0.2
1997 Hepler JR, Berman DM, Gilman AG, Kozasa T. RGS4 and GAIP are GTPase-activating proteins for Gq alpha and block activation of phospholipase C beta by gamma-thio-GTP-Gq alpha. Proceedings of the National Academy of Sciences of the United States of America. 94: 428-32. PMID 9012799 DOI: 10.1073/Pnas.94.2.428  0.2
1996 Berman DM, Kozasa T, Gilman AG. The GTPase-activating protein RGS4 stabilizes the transition state for nucleotide hydrolysis Journal of Biological Chemistry. 271: 27209-27212. PMID 8910288 DOI: 10.1074/Jbc.271.44.27209  0.2
1996 Takano K, Yasufuku-Takano J, Kozasa T, Singer WD, Nakajima S, Nakajima Y. Gq/11 and PLC-beta 1 mediate the substance P-induced inhibition of an inward rectifier K+ channel in brain neurons. Journal of Neurophysiology. 76: 2131-6. PMID 8890327 DOI: 10.1152/Jn.1996.76.3.2131  0.2
1996 Grigg JJ, Kozasa T, Nakajima Y, Nakajima S. Single-channel properties of a G-protein-coupled inward rectifier potassium channel in brain neurons Journal of Neurophysiology. 75: 318-328. PMID 8822560 DOI: 10.1152/Jn.1996.75.1.318  0.2
1996 Nakajima Y, Nakajima S, Kozasa T. Activation of G protein-coupled inward rectifier K+ channels in brain neurons requires association of G protein βγ subunits with cell membrane Febs Letters. 390: 217-220. PMID 8706863 DOI: 10.1016/0014-5793(96)00661-8  0.2
1996 Kozasa T, Gilman AG. Protein kinase C phosphorylates G12α and inhibits its interaction with Gβγ Journal of Biological Chemistry. 271: 12562-12567. PMID 8647866 DOI: 10.1074/Jbc.271.21.12562  0.2
1995 Kozasa T, Gilman AG. Purification of recombinant G proteins from Sf9 cells by hexahistidine tagging of associated subunits: Characterization of α12 and inhibition of adenylyl cyclase by αz Journal of Biological Chemistry. 270: 1734-1741. PMID 7829508 DOI: 10.1074/Jbc.270.4.1734  0.2
1994 Hepler JR, Kozasa T, Gilman AG. Purification of recombinant Gq alpha, G11 alpha, and G16 alpha from Sf9 cells. Methods in Enzymology. 237: 191-212. PMID 7934997 DOI: 10.1016/S0076-6879(94)37063-X  0.2
1993 Kozasa T, Hepler JR, Smrcka AV, Simon MI, Rhee SG, Sternweis PC, Gilman AG. Purification and characterization of recombinant G16 alpha from Sf9 cells: activation of purified phospholipase C isozymes by G-protein alpha subunits. Proceedings of the National Academy of Sciences of the United States of America. 90: 9176-80. PMID 8415674 DOI: 10.1073/Pnas.90.19.9176  0.2
2016 Masuda K, Kitakami JI, Kozasa T, Kodama T, Ihara S, Hamakubo T. Visualization of ligand-induced Gi protein activation in chemotaxing cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 27881485 DOI: 10.1096/Fj.201601102R  0.08
2010 Waldo GL, Ricks TK, Hicks SN, Cheever ML, Kawano T, Tsuboi K, Wang X, Montell C, Kozasa T, Sondek J, Harden TK. Kinetic scaffolding mediated by a phospholipase C-beta and Gq signaling complex. Science (New York, N.Y.). 330: 974-80. PMID 20966218 DOI: 10.1126/Science.1193438  0.04
2008 Shankaranarayanan A, Thal DM, Tesmer VM, Roman DL, Neubig RR, Kozasa T, Tesmer JJ. Assembly of high order G alpha q-effector complexes with RGS proteins. The Journal of Biological Chemistry. 283: 34923-34. PMID 18936096 DOI: 10.1074/Jbc.M805860200  0.04
2005 Tesmer VM, Kawano T, Shankaranarayanan A, Kozasa T, Tesmer JJ. Snapshot of activated G proteins at the membrane: the Galphaq-GRK2-Gbetagamma complex. Science (New York, N.Y.). 310: 1686-90. PMID 16339447 DOI: 10.1126/Science.1118890  0.04
2021 Obossou EK, Shikamoto Y, Hoshino Y, Kohno H, Ishibasi Y, Kozasa T, Taguchi M, Sakakibara I, Tonooka K, Shinozuka T, Mori K. Effect of manuka honey on human immunodeficiency virus type 1 reverse transcriptase activity. Natural Product Research. 1-6. PMID 33550857 DOI: 10.1080/14786419.2021.1880403  0.01
2018 Mototani Y, Okamura T, Goto M, Shimizu Y, Yanobu-Takanashi R, Ito A, Kawamura N, Yagisawa Y, Umeki D, Nariyama M, Suita K, Ohnuki Y, Shiozawa K, Sahara Y, Kozasa T, et al. Role of G protein-regulated inducer of neurite outgrowth 3 (GRIN3) in β-arrestin 2-Akt signaling and dopaminergic behaviors. Pflugers Archiv : European Journal of Physiology. PMID 29500670 DOI: 10.1007/S00424-018-2124-1  0.01
2013 Mahajan R, Ha J, Zhang M, Kawano T, Kozasa T, Logothetis DE. A computational model predicts that Gβγ acts at a cleft between channel subunits to activate GIRK1 channels. Science Signaling. 6: ra69. PMID 23943609 DOI: 10.1126/Scisignal.2004075  0.01
2012 Gan X, Wang J, Wang C, Sommer E, Kozasa T, Srinivasula S, Alessi D, Offermanns S, Simon MI, Wu D. PRR5L degradation promotes mTORC2-mediated PKC-δ phosphorylation and cell migration downstream of Gα12. Nature Cell Biology. 14: 686-96. PMID 22609986 DOI: 10.1038/Ncb2507  0.01
2011 Baba M, Kozasa T, Hamakubo T, Kuroda H, Masuda K, Yoneya S, Kodama T. Soft X-ray Laser Microscopy of Lipid Rafts towards GPCR-Based Drug Discovery Using Time-Resolved FRET Spectroscopy Pharmaceuticals. 4: 524-550. DOI: 10.3390/Ph4030524  0.01
2010 Gong H, Shen B, Flevaris P, Chow C, Lam SC, Voyno-Yasenetskaya TA, Kozasa T, Du X. G protein subunit Galpha13 binds to integrin alphaIIbbeta3 and mediates integrin "outside-in" signaling. Science (New York, N.Y.). 327: 340-3. PMID 20075254 DOI: 10.1126/Science.1174779  0.01
2007 Rojas RJ, Yohe ME, Gershburg S, Kawano T, Kozasa T, Sondek J. Galphaq directly activates p63RhoGEF and Trio via a conserved extension of the Dbl homology-associated pleckstrin homology domain. The Journal of Biological Chemistry. 282: 29201-10. PMID 17606614 DOI: 10.1074/Jbc.M703458200  0.01
2007 Kawano T, Zhao P, Floreani CV, Nakajima Y, Kozasa T, Nakajima S. Interaction of Galphaq and Kir3, G protein-coupled inwardly rectifying potassium channels. Molecular Pharmacology. 71: 1179-84. PMID 17296805 DOI: 10.1124/Mol.106.032508  0.01
2007 Baba M, Suzuki M, Ganeev RA, Kuroda H, Ozaki T, Hamakubo T, Masuda K, Hayashi M, Sakihama T, Kodama T, Kozasa T. Decay time shortening of fluorescence from donor–acceptor pair proteins using ultrafast time-resolved fluorescence resonance energy transfer spectroscopy Journal of Luminescence. 127: 355-361. DOI: 10.1016/J.Jlumin.2007.01.009  0.01
2005 Kino T, Kozasa T, Chrousos GP. Statin-induced blockade of prenylation alters nucleocytoplasmic shuttling of GTP-binding proteins gamma2 and beta2 and enhances their suppressive effect on glucocorticoid receptor transcriptional activity. European Journal of Clinical Investigation. 35: 508-13. PMID 16101671 DOI: 10.1111/J.1365-2362.2005.01539.X  0.01
2005 Kino T, Tiulpakov A, Ichijo T, Chheng L, Kozasa T, Chrousos GP. G protein beta interacts with the glucocorticoid receptor and suppresses its transcriptional activity in the nucleus. The Journal of Cell Biology. 169: 885-96. PMID 15955845 DOI: 10.1083/Jcb.200409150  0.01
2005 Koike-Tani M, Collins JM, Kawano T, Zhao P, Zhao Q, Kozasa T, Nakajima S, Nakajima Y. Signal transduction pathway for the substance P-induced inhibition of rat Kir3 (GIRK) channel. The Journal of Physiology. 564: 489-500. PMID 15731196 DOI: 10.1113/Jphysiol.2004.079285  0.01
2005 Nakata H, Kozasa T. Functional characterization of Galphao signaling through G protein-regulated inducer of neurite outgrowth 1. Molecular Pharmacology. 67: 695-702. PMID 15585744 DOI: 10.1124/Mol.104.003913  0.01
2004 Iida N, Kozasa T. Identification and biochemical analysis of GRIN1 and GRIN2. Methods in Enzymology. 390: 475-83. PMID 15488195 DOI: 10.1016/S0076-6879(04)90029-8  0.01
2004 Kozasa T. The structure of GRK2-G beta gamma complex: intimate association of G-protein signaling modules. Trends in Pharmacological Sciences. 25: 61-3. PMID 15106629 DOI: 10.1016/J.Tips.2003.12.006  0.01
2004 Kozasa T. Purification of G protein subunits from Sf9 insect cells using hexahistidine-tagged alpha and beta gamma subunits. Methods in Molecular Biology (Clifton, N.J.). 237: 21-38. PMID 14501036 DOI: 10.1385/1-59259-430-1:21  0.01
2003 Zhao Q, Kawano T, Nakata H, Nakajima Y, Nakajima S, Kozasa T. Interaction of G protein beta subunit with inward rectifier K(+) channel Kir3. Molecular Pharmacology. 64: 1085-91. PMID 14573757 DOI: 10.1124/Mol.64.5.1085  0.01
2003 Holinstat M, Mehta D, Kozasa T, Minshall RD, Malik AB. Protein kinase Calpha-induced p115RhoGEF phosphorylation signals endothelial cytoskeletal rearrangement. The Journal of Biological Chemistry. 278: 28793-8. PMID 12754211 DOI: 10.1074/Jbc.M303900200  0.01
2003 Cho H, Kozasa T, Bondjers C, Betsholtz C, Kehrl JH. Pericyte-specific expression of Rgs5: implications for PDGF and EDG receptor signaling during vascular maturation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 440-2. PMID 12514120 DOI: 10.1096/Fj.02-0340Fje  0.01
2003 Manganello JM, Huang JS, Kozasa T, Voyno-Yasenetskaya TA, Le Breton GC. Protein kinase A-mediated phosphorylation of the Galpha13 switch I region alters the Galphabetagamma13-G protein-coupled receptor complex and inhibits Rho activation. The Journal of Biological Chemistry. 278: 124-30. PMID 12399457 DOI: 10.1074/Jbc.M209219200  0.01
2002 Rochdi MD, Watier V, La Madeleine C, Nakata H, Kozasa T, Parent JL. Regulation of GTP-binding protein alpha q (Galpha q) signaling by the ezrin-radixin-moesin-binding phosphoprotein-50 (EBP50). The Journal of Biological Chemistry. 277: 40751-9. PMID 12193606 DOI: 10.1074/Jbc.M207910200  0.01
2001 Vaiskunaite R, Kozasa T, Voyno-Yasenetskaya TA. Interaction between the G alpha subunit of heterotrimeric G(12) protein and Hsp90 is required for G alpha(12) signaling. The Journal of Biological Chemistry. 276: 46088-93. PMID 11598136 DOI: 10.1074/Jbc.M108711200  0.01
2001 Shepard LW, Yang M, Xie P, Browning DD, Voyno-Yasenetskaya T, Kozasa T, Ye RD. Constitutive activation of NF-kappa B and secretion of interleukin-8 induced by the G protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus involve G alpha(13) and RhoA. The Journal of Biological Chemistry. 276: 45979-87. PMID 11590141 DOI: 10.1074/Jbc.M104783200  0.01
2001 Kozasa T. Regulation of G protein-mediated signal transduction by RGS proteins. Life Sciences. 68: 2309-17. PMID 11358341 DOI: 10.1016/S0024-3205(01)01020-7  0.01
2001 Nagata Y, Oda M, Nakata H, Shozaki Y, Kozasa T, Todokoro K. A novel regulator of G-protein signaling bearing GAP activity for Galphai and Galphaq in megakaryocytes. Blood. 97: 3051-60. PMID 11342430 DOI: 10.1182/Blood.V97.10.3051  0.01
2000 Cho H, Kozasa T, Takekoshi K, De Gunzburg J, Kehrl JH. RGS14, a GTPase-activating protein for Gialpha, attenuates Gialpha- and G13alpha-mediated signaling pathways. Molecular Pharmacology. 58: 569-76. PMID 10953050 DOI: 10.1124/Mol.58.3.569  0.01
2000 Shi CS, Sinnarajah S, Cho H, Kozasa T, Kehrl JH. G13alpha-mediated PYK2 activation. PYK2 is a mediator of G13alpha -induced serum response element-dependent transcription. The Journal of Biological Chemistry. 275: 24470-6. PMID 10821841 DOI: 10.1074/Jbc.M908449199  0.01
2000 Vaiskunaite R, Adarichev V, Furthmayr H, Kozasa T, Gudkov A, Voyno-Yasenetskaya TA. Conformational activation of radixin by G13 protein alpha subunit. The Journal of Biological Chemistry. 275: 26206-12. PMID 10816569 DOI: 10.1074/Jbc.M001863200  0.01
2000 Moratz C, Kang VH, Druey KM, Shi CS, Scheschonka A, Murphy PM, Kozasa T, Kehrl JH. Regulator of G protein signaling 1 (RGS1) markedly impairs Gi alpha signaling responses of B lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 164: 1829-38. PMID 10657631 DOI: 10.4049/Jimmunol.164.4.1829  0.01
1998 Jiang Y, Ma W, Wan Y, Kozasa T, Hattori S, Huang XY. The G protein G alpha12 stimulates Bruton's tyrosine kinase and a rasGAP through a conserved PH/BM domain. Nature. 395: 808-13. PMID 9796816 DOI: 10.1038/27454  0.01
1997 Bence K, Ma W, Kozasa T, Huang XY. Direct stimulation of Bruton's tyrosine kinase by G(q)-protein alpha-subunit. Nature. 389: 296-9. PMID 9305846 DOI: 10.1038/38520  0.01
1997 Popov S, Yu K, Kozasa T, Wilkie TM. The regulators of G protein signaling (RGS) domains of RGS4, RGS10, and GAIP retain GTPase activating protein activity in vitro. Proceedings of the National Academy of Sciences of the United States of America. 94: 7216-20. PMID 9207071 DOI: 10.1073/Pnas.94.14.7216  0.01
1996 Kozasa T, Kaziro Y, Ohtsuka T, Grigg JJ, Nakajima S, Nakajima Y. G protein specificity of the muscarine-induced increase in an inward rectifier potassium current in AtT-20 cells. Neuroscience Research. 26: 289-97. PMID 9121737 DOI: 10.1016/S0168-0102(96)01111-X  0.01
1994 Kagimoto S, Yamada Y, Kubota A, Someya Y, Ihara Y, Yasuda K, Kozasa T, Imura H, Seino S, Seino Y. Human somatostatin receptor, SSTR2, is coupled to adenylyl cyclase in the presence of Gi alpha 1 protein. Biochemical and Biophysical Research Communications. 202: 1188-95. PMID 7914078 DOI: 10.1006/bbrc.1994.2054  0.01
1994 Kubota A, Yamada Y, Kagimoto S, Yasuda K, Someya Y, Ihara Y, Okamoto Y, Kozasa T, Seino S, Seino Y. Multiple effector coupling of somatostatin receptor subtype SSTR1. Biochemical and Biophysical Research Communications. 204: 176-86. PMID 7524497 DOI: 10.1006/bbrc.1994.2442  0.01
1991 Kaziro Y, Itoh H, Kozasa T, Nakafuku M, Satoh T. Structure and function of signal-transducing GTP-binding proteins. Annual Review of Biochemistry. 60: 349-400. PMID 1909108 DOI: 10.1146/Annurev.Bi.60.070191.002025  0.01
1991 Ohoka Y, Imai S, Kozasa T, Maehama T, Takahashi K, Kaziro Y, Ui M, Katada T. Purification and characterization of a new GTP-binding protein of Mr 24,000 in bovine brain membranes. Journal of Biochemistry. 109: 428-35. PMID 1908860 DOI: 10.1093/Oxfordjournals.Jbchem.A123398  0.01
1991 Shibasaki H, Kozasa T, Takahashi K, Inanobe A, Kaziro Y, Ui M, Katada T. Amino acid sequence determination of the novel forms of Go alpha purified from bovine brain membranes. Febs Letters. 285: 268-70. PMID 1906814 DOI: 10.1016/0014-5793(91)80814-J  0.01
1991 Tsukamoto T, Toyama R, Itoh H, Kozasa T, Matsuoka M, Kaziro Y. Structure of the human gene and two rat cDNAs encoding the alpha chain of GTP-binding regulatory protein Go: two different mRNAs are generated by alternative splicing. Proceedings of the National Academy of Sciences of the United States of America. 88: 2974-8. PMID 1901650 DOI: 10.1073/Pnas.88.8.2974  0.01
1991 Garibay JL, Kozasa T, Itoh H, Tsukamoto T, Matsuoka M, Kaziro Y. Analysis by mRNA levels of the expression of six G protein alpha-subunit genes in mammalian cells and tissues. Biochimica Et Biophysica Acta. 1094: 193-9. PMID 1654117 DOI: 10.1016/0167-4889(91)90008-L  0.01
1990 Nagata K, Satoh T, Itoh H, Kozasa T, Okano Y, Doi T, Kaziro Y, Nozawa Y. The ram: a novel low molecular weight GTP-binding protein cDNA from a rat megakaryocyte library. Febs Letters. 275: 29-32. PMID 2124544 DOI: 10.1016/0014-5793(90)81431-M  0.01
1988 Kaziro Y, Itoh H, Kozasa T, Toyama R, Tsukamoto T, Matsuoka M, Nakafuku M, Obara T, Takagi T, Hernandez R. Structures of the genes coding for G-protein α subunits from mammalian and yeast cells Cold Spring Harbor Symposia On Quantitative Biology. 53: 209-220. PMID 3151168 DOI: 10.1101/Sqb.1988.053.01.027  0.01
1988 Kozasa T, Itoh H, Tsukamoto T, Kaziro Y. Isolation and characterization of the human G(s)α gene Proceedings of the National Academy of Sciences of the United States of America. 85: 2081-2085. PMID 3127824 DOI: 10.1073/Pnas.85.7.2081  0.01
1988 Matsuoka M, Itoh H, Kozasa T, Kaziro Y. Sequence analysis of cDNA and genomic DNA for a putative pertussis toxin-insensitive guanine nucleotide-binding regulatory protein alpha subunit. Proceedings of the National Academy of Sciences of the United States of America. 85: 5384-8. PMID 2456569 DOI: 10.1073/Pnas.85.15.5384  0.01
1986 Toyama K, Komatsu Y, Kozasa T. The responsiveness of Clare-Bishop neurons to size cues for motion stereopsis Neuroscience Research. 4: 83-109. PMID 3808487 DOI: 10.1016/0168-0102(86)90040-4  0.01
1986 Itoh H, Kozasa T, Nagata S, Nakamura S, Katada T, Ui M, Iwai S, Ohtsuka E, Kawasaki H, Suzuki K. Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain. Proceedings of the National Academy of Sciences of the United States of America. 83: 3776-80. PMID 3086867 DOI: 10.1073/Pnas.83.11.3776  0.01
1986 Fukui Y, Kozasa T, Kaziro Y, Takeda T, Yamamoto M. Role of a ras homolog in the life cycle of schizosaccharomyces pombe Cell. 44: 329-336. PMID 3002633 DOI: 10.1016/0092-8674(86)90767-1  0.01
1982 Toyama K, Kozasa T. Responses of Clare-Bishop neurones to three dimensional movement of a light stimulus. Vision Research. 22: 571-4. PMID 7112956 DOI: 10.1016/0042-6989(82)90115-8  0.01
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