Lester F. Lau - Publications

Affiliations: 
University of Illinois at Chicago, Health Sciences Center 
Area:
Cell Biology, Genetics, Biochemistry
Website:
https://bcmg.com.uic.edu/faculty/lau_lester.html

77 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Kim KH, Won JH, Cheng N, Lau LF. The matricellular protein CCN1 in tissue injury repair. Journal of Cell Communication and Signaling. PMID 29357009 DOI: 10.1007/s12079-018-0450-x  0.6
2018 Jun JI, Lau LF. Resolution of organ fibrosis. The Journal of Clinical Investigation. 128: 97-107. PMID 29293097 DOI: 10.1172/JCI93563  0.84
2017 Monzon RI, Kim KH, Lau LF. Construction and Analysis of an Allelic Series of Ccn1 Knockin Mice. Methods in Molecular Biology (Clifton, N.J.). 1489: 361-376. PMID 27734389 DOI: 10.1007/978-1-4939-6430-7_30  1
2016 Jun JI, Lau LF. CCN2 induces cellular senescence in fibroblasts. Journal of Cell Communication and Signaling. PMID 27752926 DOI: 10.1007/s12079-016-0359-1  0.84
2016 Lau LF. Cell surface receptors for CCN proteins. Journal of Cell Communication and Signaling. PMID 27098435 DOI: 10.1007/s12079-016-0324-z  1
2015 Kim KH, Lau LF. CCN1 in hepatobiliary injury repair. Oncotarget. 6: 34053-4. PMID 26474457 DOI: 10.18632/oncotarget.6079  1
2015 Jun JI, Kim KH, Lau LF. The matricellular protein CCN1 mediates neutrophil efferocytosis in cutaneous wound healing. Nature Communications. 6: 7386. PMID 26077348 DOI: 10.1038/ncomms8386  1
2015 Chen CC, Kim KH, Lau LF. The matricellular protein CCN1 suppresses hepatocarcinogenesis by inhibiting compensatory proliferation. Oncogene. PMID 26028023 DOI: 10.1038/onc.2015.190  1
2015 Kim KH, Chen CC, Alpini G, Lau LF. CCN1 induces hepatic ductular reaction through integrin αvβ₅-mediated activation of NF-κB. The Journal of Clinical Investigation. 125: 1886-900. PMID 25822023 DOI: 10.1172/JCI79327  1
2014 Zhao X, Ding EY, Yu OM, Xiang SY, Tan-Sah VP, Yung BS, Hedgpeth J, Neubig RR, Lau LF, Brown JH, Miyamoto S. Induction of the matricellular protein CCN1 through RhoA and MRTF-A contributes to ischemic cardioprotection. Journal of Molecular and Cellular Cardiology. 75: 152-61. PMID 25106095 DOI: 10.1016/j.yjmcc.2014.07.017  1
2013 Kim KH, Chen CC, Monzon RI, Lau LF. Matricellular protein CCN1 promotes regression of liver fibrosis through induction of cellular senescence in hepatic myofibroblasts. Molecular and Cellular Biology. 33: 2078-90. PMID 23508104 DOI: 10.1128/MCB.00049-13  1
2013 Huang Y, Li T, Eatherton A, Mitchell WL, Rong N, Ye L, Yang XJ, Jin S, Ding Y, Zhang J, Li Y, Wu Y, Jin Y, Sang Y, Cheng Z, ... Lau LF, et al. Orally bioavailable and brain-penetrant pyridazine and pyridine-derived γ-secretase modulators reduced amyloidogenic Aβ peptides in vivo. Neuropharmacology. 70: 278-86. PMID 23485401 DOI: 10.1016/j.neuropharm.2013.02.003  1
2013 Zemans RL, McClendon J, Aschner Y, Briones N, Young SK, Lau LF, Kahn M, Downey GP. Role of β-catenin-regulated CCN matricellular proteins in epithelial repair after inflammatory lung injury. American Journal of Physiology. Lung Cellular and Molecular Physiology. 304: L415-27. PMID 23316072 DOI: 10.1152/ajplung.00180.2012  1
2012 Juric V, Chen CC, Lau LF. TNFα-induced apoptosis enabled by CCN1/CYR61: pathways of reactive oxygen species generation and cytochrome c release. Plos One. 7: e31303. PMID 22363611 DOI: 10.1371/journal.pone.0031303  1
2011 Jun JI, Lau LF. Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets. Nature Reviews. Drug Discovery. 10: 945-63. PMID 22129992 DOI: 10.1038/nrd3599  0.84
2011 Park HJ, Gusarova G, Wang Z, Carr JR, Li J, Kim KH, Qiu J, Park YD, Williamson PR, Hay N, Tyner AL, Lau LF, Costa RH, Raychaudhuri P. Deregulation of FoxM1b leads to tumour metastasis. Embo Molecular Medicine. 3: 21-34. PMID 21204266 DOI: 10.1002/emmm.201000107  1
2011 Chen CC, Juric V, Lau LF. The extracellular matrix protein CCN1 dictates TNFα and FasL cytotoxicity in vivo. Advances in Experimental Medicine and Biology. 691: 595-603. PMID 21153366 DOI: 10.1007/978-1-4419-6612-4_63  1
2010 Jun JI, Lau LF. Cellular senescence controls fibrosis in wound healing. Aging. 2: 627-31. PMID 20930261  0.84
2010 Jun JI, Lau LF. The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing. Nature Cell Biology. 12: 676-85. PMID 20526329 DOI: 10.1038/ncb2070  0.84
2010 Petrovic V, Costa RH, Lau LF, Raychaudhuri P, Tyner AL. Negative regulation of the oncogenic transcription factor FoxM1 by thiazolidinediones and mithramycin. Cancer Biology & Therapy. 9: 1008-16. PMID 20372080  0.4
2010 Bai T, Chen CC, Lau LF. Matricellular protein CCN1 activates a proinflammatory genetic program in murine macrophages. Journal of Immunology (Baltimore, Md. : 1950). 184: 3223-32. PMID 20164416 DOI: 10.4049/jimmunol.0902792  1
2010 Chen CC, Lau LF. Deadly liaisons: fatal attraction between CCN matricellular proteins and the tumor necrosis factor family of cytokines. Journal of Cell Communication and Signaling. 4: 63-9. PMID 19898959 DOI: 10.1007/s12079-009-0080-4  1
2009 Chen YJ, Dominguez-Brauer C, Wang Z, Asara JM, Costa RH, Tyner AL, Lau LF, Raychaudhuri P. A conserved phosphorylation site within the forkhead domain of FoxM1B is required for its activation by cyclin-CDK1. The Journal of Biological Chemistry. 284: 30695-707. PMID 19737929 DOI: 10.1074/jbc.M109.007997  0.4
2009 Park HJ, Carr JR, Wang Z, Nogueira V, Hay N, Tyner AL, Lau LF, Costa RH, Raychaudhuri P. FoxM1, a critical regulator of oxidative stress during oncogenesis. The Embo Journal. 28: 2908-18. PMID 19696738 DOI: 10.1038/emboj.2009.239  1
2009 Katsube K, Ichikawa S, Katsuki Y, Kihara T, Terai M, Lau LF, Tamamura Y, Takeda S, Umezawa A, Sakamoto K, Yamaguchi A. CCN3 and bone marrow cells. Journal of Cell Communication and Signaling. 3: 135-45. PMID 19626464 DOI: 10.1007/s12079-009-0059-1  1
2009 Franzen CA, Chen CC, Todorović V, Juric V, Monzon RI, Lau LF. Matrix protein CCN1 is critical for prostate carcinoma cell proliferation and TRAIL-induced apoptosis. Molecular Cancer Research : McR. 7: 1045-55. PMID 19584265 DOI: 10.1158/1541-7786.MCR-09-0017  1
2009 Juric V, Chen CC, Lau LF. Fas-mediated apoptosis is regulated by the extracellular matrix protein CCN1 (CYR61) in vitro and in vivo. Molecular and Cellular Biology. 29: 3266-79. PMID 19364818 DOI: 10.1128/MCB.00064-09  1
2009 Chen CC, Lau LF. Functions and mechanisms of action of CCN matricellular proteins. The International Journal of Biochemistry & Cell Biology. 41: 771-83. PMID 18775791 DOI: 10.1016/j.biocel.2008.07.025  1
2008 Park HJ, Costa RH, Lau LF, Tyner AL, Raychaudhuri P. Anaphase-promoting complex/cyclosome-CDH1-mediated proteolysis of the forkhead box M1 transcription factor is critical for regulated entry into S phase. Molecular and Cellular Biology. 28: 5162-71. PMID 18573889 DOI: 10.1128/MCB.00387-08  0.4
2008 Pestov DG, Lapik YR, Lau LF. Assays for ribosomal RNA processing and ribosome assembly. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 22.11. PMID 18551418 DOI: 10.1002/0471143030.cb2211s39  0.6
2008 Wang IC, Chen YJ, Hughes DE, Ackerson T, Major ML, Kalinichenko VV, Costa RH, Raychaudhuri P, Tyner AL, Lau LF. FoxM1 regulates transcription of JNK1 to promote the G1/S transition and tumor cell invasiveness. The Journal of Biological Chemistry. 283: 20770-8. PMID 18524773 DOI: 10.1074/jbc.M709892200  0.4
2008 Petrovic V, Costa RH, Lau LF, Raychaudhuri P, Tyner AL. FoxM1 regulates growth factor-induced expression of kinase-interacting stathmin (KIS) to promote cell cycle progression. The Journal of Biological Chemistry. 283: 453-60. PMID 17984092 DOI: 10.1074/jbc.M705792200  0.4
2007 Lapik YR, Misra JM, Lau LF, Pestov DG. Restricting conformational flexibility of the switch II region creates a dominant-inhibitory phenotype in Obg GTPase Nog1. Molecular and Cellular Biology. 27: 7735-44. PMID 17785438 DOI: 10.1128/MCB.01161-07  0.6
2007 Chen CC, Young JL, Monzon RI, Chen N, Todorović V, Lau LF. Cytotoxicity of TNFalpha is regulated by integrin-mediated matrix signaling. The Embo Journal. 26: 1257-67. PMID 17318182 DOI: 10.1038/sj.emboj.7601596  1
2006 Raychaudhuri P, Lau LF, Grayson D, Kaplan J. Robert H. Costa: 1957-2006. Hepatology (Baltimore, Md.). 44: 1364. PMID 17058235 DOI: 10.1002/hep.21410  1
2006 Mo FE, Lau LF. The matricellular protein CCN1 is essential for cardiac development. Circulation Research. 99: 961-9. PMID 17023674 DOI: 10.1161/01.RES.0000248426.35019.89  1
2005 Todorovic V, Chen CC, Hay N, Lau LF. The matrix protein CCN1 (CYR61) induces apoptosis in fibroblasts. The Journal of Cell Biology. 171: 559-68. PMID 16275757 DOI: 10.1083/jcb.200504015  1
2005 Lin CG, Chen CC, Leu SJ, Grzeszkiewicz TM, Lau LF. Integrin-dependent functions of the angiogenic inducer NOV (CCN3): implication in wound healing. The Journal of Biological Chemistry. 280: 8229-37. PMID 15611078 DOI: 10.1074/jbc.M404903200  1
2004 Leu SJ, Chen N, Chen CC, Todorovic V, Bai T, Juric V, Liu Y, Yan G, Lam SC, Lau LF. Targeted mutagenesis of the angiogenic protein CCN1 (CYR61). Selective inactivation of integrin alpha6beta1-heparan sulfate proteoglycan coreceptor-mediated cellular functions. The Journal of Biological Chemistry. 279: 44177-87. PMID 15322081 DOI: 10.1074/jbc.M407850200  1
2004 Chen N, Leu SJ, Todorovic V, Lam SC, Lau LF. Identification of a novel integrin alphavbeta3 binding site in CCN1 (CYR61) critical for pro-angiogenic activities in vascular endothelial cells. The Journal of Biological Chemistry. 279: 44166-76. PMID 15308622 DOI: 10.1074/jbc.M406813200  1
2004 Lapik YR, Fernandes CJ, Lau LF, Pestov DG. Physical and functional interaction between Pes1 and Bop1 in mammalian ribosome biogenesis. Molecular Cell. 15: 17-29. PMID 15225545 DOI: 10.1016/j.molcel.2004.05.020  0.6
2003 Leu SJ, Liu Y, Chen N, Chen CC, Lam SC, Lau LF. Identification of a novel integrin alpha 6 beta 1 binding site in the angiogenic inducer CCN1 (CYR61). The Journal of Biological Chemistry. 278: 33801-8. PMID 12826661 DOI: 10.1074/jbc.M305862200  1
2003 Schober JM, Lau LF, Ugarova TP, Lam SC. Identification of a novel integrin alphaMbeta2 binding site in CCN1 (CYR61), a matricellular protein expressed in healing wounds and atherosclerotic lesions. The Journal of Biological Chemistry. 278: 25808-15. PMID 12736251 DOI: 10.1074/jbc.M301534200  1
2003 Lin CG, Leu SJ, Chen N, Tebeau CM, Lin SX, Yeung CY, Lau LF. CCN3 (NOV) is a novel angiogenic regulator of the CCN protein family. The Journal of Biological Chemistry. 278: 24200-8. PMID 12695522 DOI: 10.1074/jbc.M302028200  1
2003 Kim KH, Min YK, Baik JH, Lau LF, Chaqour B, Chung KC. Expression of angiogenic factor Cyr61 during neuronal cell death via the activation of c-Jun N-terminal kinase and serum response factor. The Journal of Biological Chemistry. 278: 13847-54. PMID 12576482 DOI: 10.1074/jbc.M210128200  0.6
2002 Grzeszkiewicz TM, Lindner V, Chen N, Lam SC, Lau LF. The Angiogenic Factor Cysteine-Rich 61 (CYR61, CCN1) Supports Vascular Smooth Muscle Cell Adhesion and Stimulates Chemotaxis through Integrin α6β1 and Cell Surface Heparan Sulfate Proteoglycans. Endocrinology. 143: 1441-1450. PMID 28201606 DOI: 10.1210/endo.143.4.8731  1
2002 Mo FE, Muntean AG, Chen CC, Stolz DB, Watkins SC, Lau LF. CYR61 (CCN1) is essential for placental development and vascular integrity. Molecular and Cellular Biology. 22: 8709-20. PMID 12446788 DOI: 10.1128/MCB.22.24.8709-8720.2002  1
2002 Leu SJ, Lam SC, Lau LF. Pro-angiogenic activities of CYR61 (CCN1) mediated through integrins alphavbeta3 and alpha6beta1 in human umbilical vein endothelial cells. The Journal of Biological Chemistry. 277: 46248-55. PMID 12364323 DOI: 10.1074/jbc.M209288200  1
2002 Strezoska Z, Pestov DG, Lau LF. Functional inactivation of the mouse nucleolar protein Bop1 inhibits multiple steps in pre-rRNA processing and blocks cell cycle progression. The Journal of Biological Chemistry. 277: 29617-25. PMID 12048210 DOI: 10.1074/jbc.M204381200  0.6
2002 Schober JM, Chen N, Grzeszkiewicz TM, Jovanovic I, Emeson EE, Ugarova TP, Ye RD, Lau LF, Lam SC. Identification of integrin alpha(M)beta(2) as an adhesion receptor on peripheral blood monocytes for Cyr61 (CCN1) and connective tissue growth factor (CCN2): immediate-early gene products expressed in atherosclerotic lesions. Blood. 99: 4457-65. PMID 12036876  1
2002 Grzeszkiewicz TM, Lindner V, Chen N, Lam SC, Lau LF. The angiogenic factor cysteine-rich 61 (CYR61, CCN1) supports vascular smooth muscle cell adhesion and stimulates chemotaxis through integrin alpha(6)beta(1) and cell surface heparan sulfate proteoglycans. Endocrinology. 143: 1441-50. PMID 11897702 DOI: 10.1210/endo.143.4.8731  1
2001 Chen CC, Mo FE, Lau LF. The angiogenic factor Cyr61 activates a genetic program for wound healing in human skin fibroblasts. The Journal of Biological Chemistry. 276: 47329-37. PMID 11584015 DOI: 10.1074/jbc.M107666200  1
2001 Latinkic BV, Mo FE, Greenspan JA, Copeland NG, Gilbert DJ, Jenkins NA, Ross SR, Lau LF. Promoter function of the angiogenic inducer Cyr61gene in transgenic mice: tissue specificity, inducibility during wound healing, and role of the serum response element. Endocrinology. 142: 2549-57. PMID 11356704 DOI: 10.1210/endo.142.6.8208  1
2001 Grzeszkiewicz TM, Kirschling DJ, Chen N, Lau LF. CYR61 stimulates human skin fibroblast migration through Integrin alpha vbeta 5 and enhances mitogenesis through integrin alpha vbeta 3, independent of its carboxyl-terminal domain. The Journal of Biological Chemistry. 276: 21943-50. PMID 11287419 DOI: 10.1074/jbc.M100978200  1
2001 Chen CC, Chen N, Lau LF. The angiogenic factors Cyr61 and connective tissue growth factor induce adhesive signaling in primary human skin fibroblasts. The Journal of Biological Chemistry. 276: 10443-52. PMID 11120741 DOI: 10.1074/jbc.M008087200  1
2000 Chen N, Chen CC, Lau LF. Adhesion of human skin fibroblasts to Cyr61 is mediated through integrin alpha 6beta 1 and cell surface heparan sulfate proteoglycans. The Journal of Biological Chemistry. 275: 24953-61. PMID 10821835 DOI: 10.1074/jbc.M003040200  1
1999 Jedsadayanmata A, Chen CC, Kireeva ML, Lau LF, Lam SC. Activation-dependent adhesion of human platelets to Cyr61 and Fisp12/mouse connective tissue growth factor is mediated through integrin alpha(IIb)beta(3). The Journal of Biological Chemistry. 274: 24321-7. PMID 10446209  1
1999 Babic AM, Chen CC, Lau LF. Fisp12/mouse connective tissue growth factor mediates endothelial cell adhesion and migration through integrin alphavbeta3, promotes endothelial cell survival, and induces angiogenesis in vivo. Molecular and Cellular Biology. 19: 2958-66. PMID 10082563  1
1998 Pestov DG, Grzeszkiewicz TM, Lau LF. Isolation of growth suppressors from a cDNA expression library. Oncogene. 17: 3187-97. PMID 9872334 DOI: 10.1038/sj.onc.1202260  1
1997 Shiyanov P, Hayes S, Chen N, Pestov DG, Lau LF, Raychaudhuri P. p27Kip1 induces an accumulation of the repressor complexes of E2F and inhibits expression of the E2F-regulated genes. Molecular Biology of the Cell. 8: 1815-27. PMID 9307976  0.96
1997 Kireeva ML, Latinkić BV, Kolesnikova TV, Chen CC, Yang GP, Abler AS, Lau LF. Cyr61 and Fisp12 are both ECM-associated signaling molecules: activities, metabolism, and localization during development. Experimental Cell Research. 233: 63-77. PMID 9184077 DOI: 10.1006/excr.1997.3548  1
1996 Kireeva ML, MO FE, Yang GP, Lau LF. Cyr61, a product of a growth factor-inducible immediate-early gene, promotes cell proliferation, migration, and adhesion. Molecular and Cellular Biology. 16: 1326-34. PMID 8657105  1
1994 Wu J, Lau LF, Sturgill TW. Rapid deactivation of MAP kinase in PC12 cells occurs independently of induction of phosphatase MKP-1. Febs Letters. 353: 9-12. PMID 7926031 DOI: 10.1016/0014-5793(94)01000-5  1
1991 Christy BA, Sanders LK, Lau LF, Copeland NG, Jenkins NA, Nathans D. An Id-related helix-loop-helix protein encoded by a growth factor-inducible gene. Proceedings of the National Academy of Sciences of the United States of America. 88: 1815-9. PMID 2000388  1
1990 DuBois RN, McLane MW, Ryder K, Lau LF, Nathans D. A growth factor-inducible nuclear protein with a novel cysteine/histidine repetitive sequence. The Journal of Biological Chemistry. 265: 19185-91. PMID 1699942  1
1988 Ryder K, Lau LF, Nathans D. A gene activated by growth factors is related to the oncogene v-jun. Proceedings of the National Academy of Sciences of the United States of America. 85: 1487-91. PMID 3422745  1
1988 Hazel TG, Nathans D, Lau LF. A gene inducible by serum growth factors encodes a member of the steroid and thyroid hormone receptor superfamily. Proceedings of the National Academy of Sciences of the United States of America. 85: 8444-8. PMID 3186734  1
1988 Nathans D, Lau LF, Christy B, Hartzell S, Nakabeppu Y, Ryder K. Genomic response to growth factors. Cold Spring Harbor Symposia On Quantitative Biology. 53: 893-900. PMID 3151190  1
1988 Christy BA, Lau LF, Nathans D. A gene activated in mouse 3T3 cells by serum growth factors encodes a protein with "zinc finger" sequences. Proceedings of the National Academy of Sciences of the United States of America. 85: 7857-61. PMID 3141919  1
1987 Lau LF, Nathans D. Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc. Proceedings of the National Academy of Sciences of the United States of America. 84: 1182-6. PMID 3469660  1
1985 Lau LF, Nathans D. Identification of a set of genes expressed during the G0/G1 transition of cultured mouse cells. The Embo Journal. 4: 3145-51. PMID 3841511  1
1985 Grayhack EJ, Yang XJ, Lau LF, Roberts JW. Phage lambda gene Q antiterminator recognizes RNA polymerase near the promoter and accelerates it through a pause site. Cell. 42: 259-69. PMID 2990726  1
1985 Lau LF, Roberts JW. Rho-dependent transcription termination at lambda R1 requires upstream sequences. The Journal of Biological Chemistry. 260: 574-84. PMID 2981220  1
1984 Lau LF, Roberts JW, Wu R, Georges F, Narang SA. A potential stem-loop structure and the sequence CAAUCAA in the transcript are insufficient to signal rho-dependent transcription termination at lambda tR1. Nucleic Acids Research. 12: 1287-99. PMID 6320123 DOI: 10.1093/nar/12.2.1287  1
1983 Lau LF, Roberts JW, Wu R. RNA polymerase pausing and transcript release at the lambda tR1 terminator in vitro. The Journal of Biological Chemistry. 258: 9391-7. PMID 6308007  1
1982 Lau LF, Roberts JW, Wu R. Transcription terminates at lambda tR1 in three clusters. Proceedings of the National Academy of Sciences of the United States of America. 79: 6171-5. PMID 6216477  1
1979 Rothstein RJ, Lau LF, Bahl CP, Narang SA, Wu R. Synthetic adaptors for cloning DNA. Methods in Enzymology. 68: 98-109. PMID 232227  1
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