| Year |
Citation |
Score |
| 2020 |
Li Y, Shen Y, Zhao R, Samudio I, Jia W, Bai X, Liang T. Oncolytic virotherapy in hepato-bilio-pancreatic cancer: The key to breaking the log jam? Cancer Medicine. PMID 32130786 DOI: 10.1002/Cam4.2949 |
0.319 |
|
| 2019 |
Samudio I, Hofs E, Cho B, Li M, Bolduc K, Bu L, Liu G, Lam V, Rennie P, Jia W, Elisia I, Krystal G. UV Light-inactivated HSV-1 Stimulates Natural Killer Cell-induced Killing of Prostate Cancer Cells. Journal of Immunotherapy (Hagerstown, Md. : 1997). PMID 30933043 DOI: 10.1097/Cji.0000000000000261 |
0.396 |
|
| 2017 |
Zeng Z, Liu W, Tsao T, Qiu Y, Zhao Y, Samudio I, Sarbassov DD, Kornblau SM, Baggerly KA, Kantarjian HM, Konopleva M, Andreeff M. High-throughput profiling of signaling networks identifies mechanism-based combination therapy to eliminate microenvironmental resistance in acute myeloid leukemia. Haematologica. PMID 28659338 DOI: 10.3324/Haematol.2016.162230 |
0.314 |
|
| 2016 |
Matre P, Velez J, Jacamo R, Qi Y, Su X, Cai T, Chan SM, Lodi A, Sweeney SR, Ma H, Davis RE, Baran N, Haferlach T, Su X, Flores ER, ... ... Samudio I, et al. Inhibiting glutaminase in acute myeloid leukemia: metabolic dependency of selected AML subtypes. Oncotarget. PMID 27806325 DOI: 10.18632/Oncotarget.12944 |
0.317 |
|
| 2016 |
Velez J, Pan R, Lee JT, Enciso L, Suarez M, Duque JE, Jaramillo D, Lopez C, Morales L, Bornmann W, Konopleva M, Krystal G, Andreeff M, Samudio I. Biguanides sensitize leukemia cells to ABT-737-induced apoptosis by inhibiting mitochondrial electron transport. Oncotarget. PMID 27283492 DOI: 10.18632/Oncotarget.9843 |
0.364 |
|
| 2016 |
Elisia I, Nakamura H, Lam V, Hofs E, Cederberg R, Cait J, Hughes MR, Lee L, Jia W, Adomat HH, Guns ES, McNagny KM, Samudio I, Krystal G. DMSO Represses Inflammatory Cytokine Production from Human Blood Cells and Reduces Autoimmune Arthritis. Plos One. 11: e0152538. PMID 27031833 DOI: 10.1371/Journal.Pone.0152538 |
0.37 |
|
| 2016 |
Samudio I, Rezvani K, Shaim H, Hofs E, Ngom M, Bu L, Liu G, Lee JT, Imren S, Lam V, Poon GF, Ghaedi M, Takei F, Humphries K, Jia W, et al. UV-inactivated HSV-1 potently activates NK cell killing of leukemic cells. Blood. PMID 26941401 DOI: 10.1182/Blood-2015-04-639088 |
0.399 |
|
| 2015 |
Phan L, Chou PC, Velazquez-Torres G, Samudio I, Parreno K, Huang Y, Tseng C, Vu T, Gully C, Su CH, Wang E, Chen J, Choi HH, Fuentes-Mattei E, Shin JH, et al. The cell cycle regulator 14-3-3σ opposes and reverses cancer metabolic reprogramming. Nature Communications. 6: 7530. PMID 26179207 DOI: 10.1038/Ncomms8530 |
0.337 |
|
| 2014 |
Velez J, Enciso LJ, Suarez M, Fiegl M, Grismaldo A, López C, Barreto A, Cardozo C, Palacios P, Morales L, Duque JE, Carmona JU, Konopleva M, Andreeff M, Samudio I. Platelets promote mitochondrial uncoupling and resistance to apoptosis in leukemia cells: a novel paradigm for the bone marrow microenvironment. Cancer Microenvironment : Official Journal of the International Cancer Microenvironment Society. 7: 79-90. PMID 25112275 DOI: 10.1007/S12307-014-0149-3 |
0.312 |
|
| 2014 |
Tabe Y, Harada M, Miyamae Y, Mogushi K, Kazuno S, Fujimura T, Matsushita H, Ueno T, Yokomizo T, Miida T, Samudio I, Andreeff M, Konopleva M. Bone Marrow Adipocyte-Derived Free Fatty Acids Induce Gene Signature Linking Transcription with Metabolic Changes That Contribute to Survival of Acute Monocytic Leukemia Cells Blood. 124: 1013-1013. DOI: 10.1182/Blood.V124.21.1013.1013 |
0.464 |
|
| 2013 |
Nair V, Pathi S, Jutooru I, Sreevalsan S, Basha R, Abdelrahim M, Samudio I, Safe S. Metformin inhibits pancreatic cancer cell and tumor growth and downregulates Sp transcription factors. Carcinogenesis. 34: 2870-9. PMID 23803693 DOI: 10.1093/Carcin/Bgt231 |
0.8 |
|
| 2013 |
Vélez J, Hail N, Konopleva M, Zeng Z, Kojima K, Samudio I, Andreeff M. Mitochondrial uncoupling and the reprograming of intermediary metabolism in leukemia cells. Frontiers in Oncology. 3: 67. PMID 23565503 DOI: 10.3389/Fonc.2013.00067 |
0.3 |
|
| 2013 |
Dembinski JL, Wilson SM, Spaeth EL, Studeny M, Zompetta C, Samudio I, Roby K, Andreeff M, Marini FC. Tumor stroma engraftment of gene-modified mesenchymal stem cells as anti-tumor therapy against ovarian cancer. Cytotherapy. 15: 20-32. PMID 23260083 DOI: 10.1016/J.Jcyt.2012.10.003 |
0.307 |
|
| 2013 |
Matre P, Samudio I, Jacamo R, Wang Y, Wang J, Davis RE, Su X, Schindela S, Newman R, Hu J, Haferlach T, Andreeff M, Flores ER, Schimmer A, Konopleva M. Unraveling The Molecular and Metabolic Basis For Glutamine Addiction In Leukemias Blood. 122: 606-606. DOI: 10.1182/Blood.V122.21.606.606 |
0.426 |
|
| 2012 |
Zhou L, Ruvolo VR, McQueen T, Chen W, Samudio IJ, Conneely O, Konopleva M, Andreeff M. HDAC inhibition by SNDX-275 (Entinostat) restores expression of silenced leukemia-associated transcription factors Nur77 and Nor1 and of key pro-apoptotic proteins in AML. Leukemia. 27: 1358-68. PMID 23247046 DOI: 10.1182/Blood.V112.11.311.311 |
0.487 |
|
| 2012 |
Frolova O, Samudio I, Benito JM, Jacamo R, Kornblau SM, Markovic A, Schober W, Lu H, Qiu YH, Buglio D, McQueen T, Pierce S, Shpall E, Konoplev S, Thomas D, et al. Regulation of HIF-1α signaling and chemoresistance in acute lymphocytic leukemia under hypoxic conditions of the bone marrow microenvironment. Cancer Biology & Therapy. 13: 858-70. PMID 22785211 DOI: 10.4161/Cbt.20838 |
0.407 |
|
| 2012 |
Ruvolo PP, Jacamo R, McQueen T, Pan R, Samudio I, Konopleva M, Kornblau SM, Garzon R, Croce CM, Andreeff M. Suppression of Mir-93 May Regulate Anti-Oxidant Metabolism in Mesenchymal Stromal Cells Derived From Acute Myeloid Leukemia Patients. Blood. 120: 2354-2354. DOI: 10.1182/Blood.V120.21.2354.2354 |
0.318 |
|
| 2012 |
Duque JE, Velez J, Samudio I, Lai E. Metformin as a Novel Component of Metronomic Chemotherapeutic Use: A Hypothesis Journal of Experimental & Clinical Medicine. 4: 140-144. DOI: 10.1016/J.Jecm.2012.04.002 |
0.355 |
|
| 2011 |
Jutooru I, Chadalapaka G, Abdelrahim M, Basha MR, Samudio I, Konopleva M, Andreeff M, Safe SH. Methyl 2-cyano-3,12-dioxooleana-1, 9-dien-28-oate decreases specificity protein transcription factors and inhibits pancreatic tumor growth: Role of microRNA-27a (Molecular Pharmacology (2010) 78, (226-236)) Molecular Pharmacology. 79. DOI: 10.1124/Mol.79.2.336 |
0.719 |
|
| 2010 |
Fiegl M, Samudio I, Mnjoyan Z, Korchin B, Fritsche H, Andreeff M. Physiological hypoxia promotes lipid raft and PI3K-dependent activation of MAPK 42/44 in leukemia cells Leukemia. 24: 1364-1367. PMID 20508615 DOI: 10.1038/Leu.2010.94 |
0.4 |
|
| 2010 |
Jutooru I, Chadalapaka G, Abdelrahim M, Basha MR, Samudio I, Konopleva M, Andreeff M, Safe S. Methyl 2-cyano-3,12-dioxooleana-1,9-dien-28-oate decreases specificity protein transcription factors and inhibits pancreatic tumor growth: role of microRNA-27a. Molecular Pharmacology. 78: 226-36. PMID 20488920 DOI: 10.1124/Mol.110.064451 |
0.797 |
|
| 2010 |
Samudio IJ, Duvvuri S, Clise-Dwyer K, Watt JC, Mak D, Kantarjian H, Yang D, Ruvolo V, Borthakur G. Activation of p53 signaling by MI-63 induces apoptosis in acute myeloid leukemia cells. Leukemia & Lymphoma. 51: 911-9. PMID 20423286 DOI: 10.3109/10428191003731325 |
0.404 |
|
| 2010 |
Samudio I, Konopleva M, Carter B, Andreeff M. Apoptosis in leukemias: regulation and therapeutic targeting. Cancer Treatment and Research. 145: 197-217. PMID 20306253 DOI: 10.1007/978-0-387-69259-3_12 |
0.326 |
|
| 2010 |
Kidd S, Caldwell L, Dietrich M, Samudio I, Spaeth EL, Watson K, Shi Y, Abbruzzese J, Konopleva M, Andreeff M, Marini FC. Mesenchymal stromal cells alone or expressing interferon-β suppress pancreatic tumors in vivo, an effect countered by anti-inflammatory treatment Cytotherapy. 12: 615-625. PMID 20230221 DOI: 10.3109/14653241003631815 |
0.309 |
|
| 2010 |
Samudio I, Harmancey R, Fiegl M, Kantarjian H, Konopleva M, Korchin B, Kaluarachchi K, Bornmann W, Duvvuri S, Taegtmeyer H, Andreeff M. Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction Journal of Clinical Investigation. 120: 142-156. PMID 20038799 DOI: 10.1172/Jci38942 |
0.391 |
|
| 2009 |
Samudio I, Fiegl M, Andreeff M. Mitochondrial uncoupling and the Warburg effect: molecular basis for the reprogramming of cancer cell metabolism. Cancer Research. 69: 2163-6. PMID 19258498 DOI: 10.1158/0008-5472.Can-08-3722 |
0.315 |
|
| 2009 |
Fiegl M, Samudio I, Clise-Dwyer K, Burks JK, Mnjoyan Z, Andreeff M. CXCR4 expression and biologic activity in acute myeloid leukemia are dependent on oxygen partial pressure. Blood. 113: 1504-12. PMID 18957686 DOI: 10.1182/Blood-2008-06-161539 |
0.362 |
|
| 2009 |
Zeng Z, Shi YX, Samudio IJ, Wang RY, Ling X, Frolova O, Levis M, Rubin JB, Negrin RR, Estey EH, Konoplev S, Andreeff M, Konopleva M. Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML. Blood. 113: 6215-24. PMID 18955566 DOI: 10.1182/Blood-2008-05-158311 |
0.412 |
|
| 2009 |
Andreeff M, Fiegl M, Konopleva M, Korchin B, Kaluarachchi K, Bornmann WG, Guthrie PH, Harmancey R, Taegtmeyer H, Samudio IJ. Pharmacological Inhibition of Fatty Acid Oxidation as a Novel Therapeutic Concept for Acute Myeloid Leukemia. Blood. 114: 3779-3779. DOI: 10.1182/Blood.V114.22.3779.3779 |
0.427 |
|
| 2009 |
Borthakur G, Duvvuri S, Samudio IJ, Kojima K, Konopleva M, Andreeff M. Synergistic Activation of p53 Family of Proteins by the Combination of Nutlin 3a and SAHA in Acute Myelogenous Leukemia. Blood. 114: 1738-1738. DOI: 10.1182/Blood.V114.22.1738.1738 |
0.367 |
|
| 2008 |
Samudio I, Fiegl M, McQueen T, Clise-Dwyer K, Andreeff M. The warburg effect in leukemia-stroma cocultures is mediated by mitochondrial uncoupling associated with uncoupling protein 2 activation. Cancer Research. 68: 5198-205. PMID 18593920 DOI: 10.1158/0008-5472.Can-08-0555 |
0.411 |
|
| 2008 |
Samudio I, Kurinna S, Ruvolo P, Korchin B, Kantarjian H, Beran M, Dunner K, Kondo S, Andreeff M, Konopleva M. Inhibition of mitochondrial metabolism by methyl-2-cyano-3,12-dioxooleana-1,9-diene-28-oate induces apoptotic or autophagic cell death in chronic myeloid leukemia cells. Molecular Cancer Therapeutics. 7: 1130-9. PMID 18483301 DOI: 10.1158/1535-7163.Mct-07-0553 |
0.367 |
|
| 2008 |
Konopleva M, Watt J, Contractor R, Tsao T, Harris D, Estrov Z, Bornmann W, Kantarjian H, Viallet J, Samudio I, Andreeff M. Mechanisms of antileukemic activity of the novel Bcl-2 homology domain-3 mimetic GX15-070 (Obatoclax) Cancer Research. 68: 3413-3420. PMID 18451169 DOI: 10.1158/0008-5472.Can-07-1919 |
0.431 |
|
| 2008 |
Hong J, Samudio I, Chintharlapalli S, Safe S. 1,1-bis(3'-indolyl)-1-(p-substituted phenyl)methanes decrease mitochondrial membrane potential and induce apoptosis in endometrial and other cancer cell lines. Molecular Carcinogenesis. 47: 492-507. PMID 18085536 DOI: 10.1002/Mc.20407 |
0.721 |
|
| 2008 |
Fiegl M, Samudio IJ, Dwyer KC, Burks J, Fritsche H, Mnjoyan ZH, Andreeff M. CXCR4 Expression and Biological Activity Is Dependent on Oxygen Partial Pressure in Acute Myeloid Leukemia. Blood. 112: 938-938. DOI: 10.1182/Blood.V112.11.938.938 |
0.334 |
|
| 2008 |
Frolova O, Samudio IJ, Mnjoyan ZH, Lu H, Konoplev S, Thomas DA, Kantarjian HM, Shpall EJ, Andreeff M, Konopleva M. Targeting the Hypoxic Microenvironment by mTOR Inhibitors Sensitizes ALL Cells to Chemotherapy Blood. 112: 18-18. DOI: 10.1182/Blood.V112.11.18.18 |
0.385 |
|
| 2008 |
Samudio IJ, Fiegl M, Konopleva M, Kaluarachchi K, McMurray JS, Korchin B, Dwyer KC, Harmancey R, Guthrie P, Taegtmeyer H, Andreeff M. Targeting Anaplerotic Pathways That Support Fatty Acid Metabolism as a Therapeutic Strategy for Hematological Malignancies: The Achilles’ Heel of the Warburg Effect. Blood. 112: 1631-1631. DOI: 10.1182/Blood.V112.11.1631.1631 |
0.363 |
|
| 2007 |
Kojima K, Konopleva M, Samudio IJ, Ruvolo V, Andreeff M. Mitogen-activated protein kinase kinase inhibition enhances nuclear proapoptotic function of p53 in acute myelogenous leukemia cells. Cancer Research. 67: 3210-9. PMID 17409429 DOI: 10.1158/0008-5472.Can-06-2712 |
0.383 |
|
| 2007 |
Zeng Z, Sarbassov dos D, Samudio IJ, Yee KW, Munsell MF, Ellen Jackson C, Giles FJ, Sabatini DM, Andreeff M, Konopleva M. Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML. Blood. 109: 3509-12. PMID 17179228 DOI: 10.1182/Blood-2006-06-030833 |
0.377 |
|
| 2007 |
Andreeff M, Dietrich M, Corn P, Konoplev S, Konopleva M, Samudio I. The Hypoxic Microenvironment in Acute Myelogenous Leukemia: Critical Role of CXCR4 in the Induction of HIF-1α. Blood. 110: 1819-1819. DOI: 10.1182/Blood.V110.11.1819.1819 |
0.346 |
|
| 2007 |
Wang R, Samudio IJ, McQueen T, Schober WD, Ruvolo VR, Kornblau S, Konopleva M, Andreeff M. Apoptosis Inducing Factor Acts as a Survival Factor in Acute Myelogenous Leukemia through Mitochondrial Complex 1. Blood. 110: 1812-1812. DOI: 10.1182/Blood.V110.11.1812.1812 |
0.37 |
|
| 2006 |
Kojima K, Konopleva M, Samudio IJ, Schober WD, Bornmann WG, Andreeff M. Concomitant inhibition of MDM2 and Bcl-2 protein function synergistically induce mitochondrial apoptosis in AML Cell Cycle. 5: 2778-2786. PMID 17172851 DOI: 10.4161/Cc.5.23.3520 |
0.409 |
|
| 2006 |
Zeng Z, Samudio IJ, Munsell M, An J, Huang Z, Estey E, Andreeff M, Konopleva M. Inhibition of CXCR4 with the novel RCP168 peptide overcomes stroma-mediated chemoresistance in chronic and acute leukemias. Molecular Cancer Therapeutics. 5: 3113-21. PMID 17172414 DOI: 10.1158/1535-7163.Mct-06-0228 |
0.412 |
|
| 2006 |
Konopleva M, Contractor R, Tsao T, Samudio I, Ruvolo PP, Kitada S, Deng X, Zhai D, Shi YX, Sneed T, Verhaegen M, Soengas M, Ruvolo VR, McQueen T, Schober WD, et al. Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia. Cancer Cell. 10: 375-88. PMID 17097560 DOI: 10.1016/J.Ccr.2006.10.006 |
0.43 |
|
| 2006 |
Zeng Z, Samudio IJ, Zhang W, Estrov Z, Pelicano H, Harris D, Frolova O, Hail N, Chen W, Kornblau SM, Huang P, Lu Y, Mills GB, Andreeff M, Konopleva M. Simultaneous inhibition of PDK1/AKT and Fms-like tyrosine kinase 3 signaling by a small-molecule KP372-1 induces mitochondrial dysfunction and apoptosis in acute myelogenous leukemia. Cancer Research. 66: 3737-46. PMID 16585200 DOI: 10.1158/0008-5472.Can-05-1278 |
0.367 |
|
| 2006 |
Samudio I, Konopleva M, Pelicano H, Huang P, Frolova O, Bornmann W, Ying Y, Evans R, Contractor R, Andreeff M. A novel mechanism of action of methyl-2-cyano-3,12 dioxoolean-1,9 diene-28-oate: Direct permeabilization of the inner mitochondrial membrane to inhibit electron transport and induce apoptosis Molecular Pharmacology. 69: 1182-1193. PMID 16410408 DOI: 10.1124/Mol.105.018051 |
0.325 |
|
| 2006 |
Samudio I, Konopleva M, Safe S, McQueen T, Andreeff M. Guggulsterones induce apoptosis and differentiation in acute myeloid leukemia: identification of isomer-specific antileukemic activities of the pregnadienedione structure. Molecular Cancer Therapeutics. 4: 1982-92. PMID 16373713 DOI: 10.1158/1535-7163.Mct-05-0247 |
0.509 |
|
| 2006 |
Abdelrahim M, Newman K, Vanderlaag K, Samudio I, Safe S. 3,3'-diindolylmethane (DIM) and its derivatives induce apoptosis in pancreatic cancer cells through endoplasmic reticulum stress-dependent upregulation of DR5. Carcinogenesis. 27: 717-28. PMID 16332727 DOI: 10.1093/Carcin/Bgi270 |
0.574 |
|
| 2006 |
Andreeff M, Konopleva M, Watt JC, Samudio IJ, Satterthwait AC, Kitada S, Zhang X, Reed JC. A Novel Peptide Containing a Nine Amino Acid Sequence from Nur77 Induces Bcl-2-Dependent Apoptosis in AML. Blood. 108: 2607-2607. DOI: 10.1182/Blood.V108.11.2607.2607 |
0.378 |
|
| 2006 |
Samudio I, Dietrich M, Corn P, Yang D, Borthakur G. Novel Small Molecule MDM2 Inhibitor MI-63 Induces p53-Dependent Apoptosis in AML Cell Lines. Blood. 108: 2596-2596. DOI: 10.1182/Blood.V108.11.2596.2596 |
0.408 |
|
| 2006 |
Frolova O, Buglio D, Samudio I, McQueen T, Kantarjian H, Weiser MA, Andreeff M, Konopleva M. Relationship between mTOR-Mediated Upregulation of Glycolysis and Chemosensitivity of ALL Blasts. Blood. 108: 1833-1833. DOI: 10.1182/Blood.V108.11.1833.1833 |
0.385 |
|
| 2006 |
Zeng Z, Sarbassov DD, Giles FJ, Samudio I, Yee KW, Jackson CE, Sabatini DM, Andreeff M, Konopleva M. Rapamycin Analogs Reduce mTORC2 Signaling and Inhibit AKT Activation in AML. Blood. 108: 156-156. DOI: 10.1182/Blood.V108.11.156.156 |
0.347 |
|
| 2005 |
Calabrò P, Samudio I, Safe SH, Willerson JT, Yeh ET. Inhibition of tumor-necrosis-factor-alpha induced endothelial cell activation by a new class of PPAR-gamma agonists. An in vitro study showing receptor-independent effects. Journal of Vascular Research. 42: 509-16. PMID 16155367 DOI: 10.1159/000088260 |
0.442 |
|
| 2005 |
Samudio I, Konopleva M, Hail N, Shi YX, McQueen T, Hsu T, Evans R, Honda T, Gribble GW, Sporn M, Gilbert HF, Safe S, Andreeff M. 2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im) directly targets mitochondrial glutathione to induce apoptosis in pancreatic cancer. The Journal of Biological Chemistry. 280: 36273-82. PMID 16118208 DOI: 10.1074/Jbc.M507518200 |
0.498 |
|
| 2005 |
Vanderlaag K, Samudio I, Burghardt R, Barhoumi R, Safe S. Inhibition of breast cancer cell growth and induction of cell death by 1,1-bis(3'-indolyl)methane (DIM) and 5,5'-dibromoDIM. Cancer Letters. 236: 198-212. PMID 16051428 DOI: 10.1016/J.Canlet.2005.05.036 |
0.594 |
|
| 2005 |
Kojima K, Konopleva M, Samudio IJ, Shikami M, Cabreira-Hansen M, McQueen T, Ruvolo V, Tsao T, Zeng Z, Vassilev LT, Andreeff M. MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy. Blood. 106: 3150-9. PMID 16014563 DOI: 10.1182/Blood-2005-02-0553 |
0.414 |
|
| 2005 |
Contractor R, Samudio IJ, Estrov Z, Harris D, McCubrey JA, Safe SH, Andreeff M, Konopleva M. A novel ring-substituted diindolylmethane,1,1-bis[3'-(5-methoxyindolyl)]-1-(p-t-butylphenyl) methane, inhibits extracellular signal-regulated kinase activation and induces apoptosis in acute myelogenous leukemia. Cancer Research. 65: 2890-8. PMID 15805291 DOI: 10.1158/0008-5472.Can-04-3781 |
0.564 |
|
| 2005 |
Chintharlapalli S, Papineni S, Konopleva M, Andreef M, Samudio I, Safe S. 2-Cyano-3,12-dioxoolean-1,9-dien-28-oic acid and related compounds inhibit growth of colon cancer cells through peroxisome proliferator-activated receptor gamma-dependent and -independent pathways. Molecular Pharmacology. 68: 119-28. PMID 15798084 DOI: 10.1124/Mol.105.011437 |
0.815 |
|
| 2005 |
Samudio I, Konopleva M, Safe S, Andreeff M. Guggulsterones Induce Apoptosis and Differentiation in AML: Identification of Isomer-Specific Antileukemic Activities of the Pregnanedienedione Structure. Blood. 106: 4466-4466. DOI: 10.1182/Blood.V106.11.4466.4466 |
0.512 |
|
| 2005 |
Samudio I, Konopleva M, Pelicano H, Huang P, Frolova O, Bornmann W, Ying Y, Evans R, Andreeff M. A Novel Mechanism of Action of Methyl-2-cyano-3,12 dioxoolean-1,9 diene-28-oate (CDDO-Me): Direct Permeabilization of the Inner Mitochondrial Membrane To Inhibit Electron Transport and Induce Apoptosis. Blood. 106: 4462-4462. DOI: 10.1182/Blood.V106.11.4462.4462 |
0.329 |
|
| 2005 |
Kojima K, Konopleva M, Samudio IJ, McQueen T, Tsao T, Zeng Z, Plunkett WK, Andreeff M. MDM2 Inhibitor Nutlin-3a Induces p53-Dependent Apoptosis Via Transcription-Dependent and -Independent Pathways and Overcomes Fludarabine-Resistance in CLL. Blood. 106: 445-445. DOI: 10.1182/Blood.V106.11.445.445 |
0.387 |
|
| 2005 |
Contractor R, Konopleva M, Samudio I, Kantarjian H, Andreeff M. Inhibition of Bcl-2 Signaling by Small Molecule BH3 Inhibitor GX15-070 as a Novel Therapeutic Strategy in AML. Blood. 106: 3372-3372. DOI: 10.1182/Blood.V106.11.3372.3372 |
0.421 |
|
| 2005 |
Konopleva M, Samudio I, Tsao T, Kornblau SM, Shi Y, McQueen T, Contractor R, Sporn MB, Meyer CJ, Huff W, Safe SH, Kantarjian H, Andreeff M. Mechanisms and Activity of PPARγ-Active Triterpenoids CDDO and CDDO-Me in Leukemias. Blood. 106: 2460-2460. DOI: 10.1182/Blood.V106.11.2460.2460 |
0.478 |
|
| 2005 |
Andreeff M, Contractor R, Ruvolo PP, Deng X, Samudio I, Shi Y, McQueen T, Wang R, Schober W, Ling X, Marini FC, Harris D, Estrov Z, McCubrey J, May WS, et al. Mechanisms of Apoptosis Induction by BH3 Inhibitor ABT-737 in AML. Blood. 106: 244-244. DOI: 10.1182/Blood.V106.11.244.244 |
0.435 |
|
| 2005 |
Buglio D, Konopleva M, McQueen T, Samudio I, Broglio KR, Ruvolo V, Contractor R, Chen W, Kantarjian H, Andreeff M, Weiser MA. Relationship between m-TOR-Mediated Upregulation of Glycolysis, Chemoresistance, and Prognosis in Patients with ALL. Blood. 106: 12-12. DOI: 10.1182/Blood.V106.11.12.12 |
0.355 |
|
| 2004 |
Hong J, Samudio I, Liu S, Abdelrahim M, Safe S. Peroxisome proliferator-activated receptor gamma-dependent activation of p21 in Panc-28 pancreatic cancer cells involves Sp1 and Sp4 proteins. Endocrinology. 145: 5774-85. PMID 15345676 DOI: 10.1210/En.2004-0686 |
0.565 |
|
| 2004 |
Chintharlapalli S, Smith R, Samudio I, Zhang W, Safe S. 1,1-Bis(3'-indolyl)-1-(p-substitutedphenyl)methanes induce peroxisome proliferator-activated receptor gamma-mediated growth inhibition, transactivation, and differentiation markers in colon cancer cells. Cancer Research. 64: 5994-6001. PMID 15342379 DOI: 10.1158/0008-5472.Can-04-0399 |
0.719 |
|
| 2004 |
Qin C, Samudio I, Ngwenya S, Safe S. Estrogen-dependent regulation of ornithine decarboxylase in breast cancer cells through activation of nongenomic cAMP-dependent pathways. Molecular Carcinogenesis. 40: 160-70. PMID 15224348 DOI: 10.1002/Mc.20030 |
0.785 |
|
| 2004 |
Qin C, Morrow D, Stewart J, Spencer K, Porter W, Smith R, Phillips T, Abdelrahim M, Samudio I, Safe S. A new class of peroxisome proliferator-activated receptor gamma (PPARgamma) agonists that inhibit growth of breast cancer cells: 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes. Molecular Cancer Therapeutics. 3: 247-60. PMID 15026545 |
0.782 |
|
| 2004 |
Safe S, Wormke M, Samudio I. Mechanisms of inhibitory aryl hydrocarbon receptor-estrogen receptor crosstalk in human breast cancer cells. Journal of Mammary Gland Biology and Neoplasia. 5: 295-306. PMID 14973392 DOI: 10.1023/A:1009550912337 |
0.838 |
|
| 2004 |
Stoner M, Wormke M, Saville B, Samudio I, Qin C, Abdelrahim M, Safe S. Estrogen regulation of vascular endothelial growth factor gene expression in ZR-75 breast cancer cells through interaction of estrogen receptor alpha and SP proteins. Oncogene. 23: 1052-63. PMID 14647449 DOI: 10.1038/Sj.Onc.1207201 |
0.806 |
|
| 2004 |
Contractor R, Samudio IJ, Estrov Z, Harris D, McCubrey JA, Safe SH, Andreeff M, Konopleva M. A Novel Ring-Substituted Diindolylmethane 1,1-bis [3′-(5-methoxyindolyl)]-1-(p-t-butylphenyl) Methane Abrogates ERK Activation and Induces Apoptosis in Acute Myeloid Leukemia (AML). Blood. 104: 3399-3399. DOI: 10.1182/Blood.V104.11.3399.3399 |
0.554 |
|
| 2004 |
Shikami M, Konopleva M, Samudio I, Hoshino K, Garcia-Manero G, Kojima K, Tsao T, McQueen T, Andreeff M. ARTS, a Pro-Apoptotic Mitochondrial Septin-Like Protein That Binds to XIAP, Is Silenced in Acute Lymphoblastic and Primitive Acute Myeloblastic Leukemia Cells. Blood. 104: 3378-3378. DOI: 10.1182/Blood.V104.11.3378.3378 |
0.427 |
|
| 2003 |
Khan S, Abdelrahim M, Samudio I, Safe S. Estrogen receptor/Sp1 complexes are required for induction of cad gene expression by 17beta-estradiol in breast cancer cells. Endocrinology. 144: 2325-35. PMID 12746293 DOI: 10.1210/En.2002-0149 |
0.754 |
|
| 2002 |
Qin C, Nguyen T, Stewart J, Samudio I, Burghardt R, Safe S. Estrogen up-regulation of p53 gene expression in MCF-7 breast cancer cells is mediated by calmodulin kinase IV-dependent activation of a nuclear factor kappaB/CCAAT-binding transcription factor-1 complex. Molecular Endocrinology (Baltimore, Md.). 16: 1793-809. PMID 12145335 DOI: 10.1210/Me.2002-0006 |
0.795 |
|
| 2002 |
Abdelrahim M, Samudio I, Smith R, Burghardt R, Safe S. Small inhibitory RNA duplexes for Sp1 mRNA block basal and estrogen-induced gene expression and cell cycle progression in MCF-7 breast cancer cells. The Journal of Biological Chemistry. 277: 28815-22. PMID 12052832 DOI: 10.1074/Jbc.M203828200 |
0.59 |
|
| 2002 |
Wang F, Samudio I, Safe S. Transcriptional activation of rat creatine kinase B by 17beta-estradiol in MCF-7 cells involves an estrogen responsive element and GC-rich sites. Journal of Cellular Biochemistry. 84: 156-72. PMID 11746525 DOI: 10.1002/Jcb.1276 |
0.586 |
|
| 2002 |
Saville B, Poukka H, Wormke M, Jänne OA, Palvimo JJ, Stoner M, Samudio I, Safe S. Cooperative coactivation of estrogen receptor α in ZR-75 human breast cancer cells by SNURF and TATA-binding protein Journal of Biological Chemistry. 277: 2485-2497. PMID 11696545 DOI: 10.1074/Jbc.M109021200 |
0.757 |
|
| 2001 |
Samudio I, Vyhlidal C, Wang F, Stoner M, Chen I, Kladde M, Barhoumi R, Burghardt R, Safe S. Transcriptional Activation of Deoxyribonucleic Acid Polymerase α Gene Expression in MCF-7 Cells by 17β-Estradiol. Endocrinology. 142: 1000-1008. PMID 28201425 DOI: 10.1210/Endo.142.3.8022 |
0.805 |
|
| 2001 |
Castro-Rivera E, Samudio I, Safe S. Estrogen regulation of cyclin D1 gene expression in ZR-75 breast cancer cells involves multiple enhancer elements. The Journal of Biological Chemistry. 276: 30853-61. PMID 11410592 DOI: 10.1074/Jbc.M103339200 |
0.596 |
|
| 2001 |
Wang F, Samudio I, Safe S. Transcriptional activation of cathepsin D gene expression by 17beta-estradiol: mechanism of aryl hydrocarbon receptor-mediated inhibition. Molecular and Cellular Endocrinology. 172: 91-103. PMID 11165043 DOI: 10.1016/S0303-7207(00)00379-8 |
0.592 |
|
| 2000 |
Xie W, Duan R, Chen I, Samudio I, Safe S. Transcriptional activation of thymidylate synthase by 17beta-estradiol in MCF-7 human breast cancer cells. Endocrinology. 141: 2439-49. PMID 10875244 DOI: 10.1210/Endo.141.7.7538 |
0.711 |
|
| 2000 |
Vyhlidal C, Samudio I, Kladde MP, Safe S. Transcriptional activation of transforming growth factor alpha by estradiol: requirement for both a GC-rich site and an estrogen response element half-site. Journal of Molecular Endocrinology. 24: 329-38. PMID 10828826 DOI: 10.1677/Jme.0.0240329 |
0.791 |
|
| 2000 |
Stoner M, Wang F, Wormke M, Nguyen T, Samudio I, Vyhlidal C, Marme D, Finkenzeller G, Safe S. Inhibition of vascular endothelial growth factor expression in HEC1A endometrial cancer cells through interactions of estrogen receptor alpha and Sp3 proteins. The Journal of Biological Chemistry. 275: 22769-79. PMID 10816575 DOI: 10.1074/Jbc.M002188200 |
0.805 |
|
| 1999 |
Dong L, Wang W, Wang F, Stoner M, Reed JC, Harigai M, Samudio I, Kladde MP, Vyhlidal C, Safe S. Mechanisms of transcriptional activation of bcl-2 gene expression by 17beta-estradiol in breast cancer cells. The Journal of Biological Chemistry. 274: 32099-107. PMID 10542244 DOI: 10.1074/Jbc.274.45.32099 |
0.832 |
|
| 1999 |
Duan R, Porter W, Samudio I, Vyhlidal C, Kladde M, Safe S. Transcriptional activation of c-fos protooncogene by 17beta-estradiol: mechanism of aryl hydrocarbon receptor-mediated inhibition. Molecular Endocrinology (Baltimore, Md.). 13: 1511-21. PMID 10478842 DOI: 10.1210/Mend.13.9.0338 |
0.801 |
|
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