Shawn D. Spencer, Ph.D. - Publications

Affiliations: 
2004 Temple University, Philadelphia, PA, United States 
Area:
Pharmaceutical Chemistry, Biochemistry

8/42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Udofot O, Jaruszewski K, Spencer S, Agyare E. Development of a novel approach to enhance the solubility of ftibamzone formulation. Integrative Molecular Medicine. 1: 61-66. PMID 26120473 DOI: 10.15761/Imm.1000111  0.341
2014 Spencer SD, Rosen LS, Gordon MS, Robert F, Matei D, Peer CJ, Adams B, Alvarez D, Seon BK, Theuer CP, Figg WD. Abstract CT222: Differences in pharmacokinetics of TRC105 (anti-endoglin antibody) when administered as a single agent versus in combination with bevacizumab (Bev) Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Ct222  0.308
2013 Gordon MS, Rosen LS, Mendelson D, Ramanathan RK, Goldman J, Liu L, Xu Y, Gerson SL, Anthony SP, Figg WD, Spencer S, Adams BJ, Theuer CP, Leigh BR, Weiss GJ. A phase 1 study of TRC102, an inhibitor of base excision repair, and pemetrexed in patients with advanced solid tumors. Investigational New Drugs. 31: 714-23. PMID 23054206 DOI: 10.1007/S10637-012-9876-9  0.304
2011 Wang XY, He ZC, Song LY, Spencer S, Yang LX, Peng F, Liu GM, Hu MH, Li HB, Wu XM, Zeng S, Hilgenfeld R, Stöckigt J, Zhao Y, Qian JF. Chemotherapeutic effects of bioassay-guided extracts of the American cockroach, Periplaneta americana. Integrative Cancer Therapies. 10: NP12-23. PMID 21733985 DOI: 10.1177/1534735411413467  0.3
2004 Spencer SD, Raffa RB. Isothermal titration calorimetric study of RNase-A kinetics (cCMP --> 3'-CMP) involving end-product inhibition. Pharmaceutical Research. 21: 1642-7. PMID 15497691 DOI: 10.1023/B:Pham.0000041460.78128.0F  0.501
2004 Raffa RB, Stagliano GW, Spencer SD. Protonation effect on drug affinity. European Journal of Pharmacology. 483: 323-4. PMID 14729124 DOI: 10.1016/J.Ejphar.2003.10.019  0.637
2002 Raffa RB, Spencer SD, Schulingkamp RJ. Toward RNase inhibitors: thermodynamics of 2'-CMP/RNase-A binding in multi-ion buffer. Biochemical Pharmacology. 63: 1937-9. PMID 12093469 DOI: 10.1016/S0006-2952(02)00977-2  0.674
2002 Spencer SD, Abdul O, Schulingkamp RJ, Raffa RB. Toward the design of ribonuclease (RNase) inhibitors: ion effects on the thermodynamics of binding of 2'-CMP to RNase A. The Journal of Pharmacology and Experimental Therapeutics. 301: 925-9. PMID 12023520 DOI: 10.1124/Jpet.301.3.925  0.671
Low-probability matches (unlikely to be authored by this person)
2012 Figg WD, Spencer SD, Pisle ST, Pressler HM, Troutman SM, Eisner JR, Rafferty SW, Schotzinger RJ, Moore WR. Activity of oral VT-464, a selective CYP17-lyase inhibitor, in the LNCaP prostate cancer xenograft. Journal of Clinical Oncology. 30: 4671-4671. DOI: 10.1200/Jco.2012.30.15_Suppl.4671  0.29
2013 Peer CJ, Brown JL, Martin TJ, Roth J, Spencer SD, Brassil P, McNeill KA, Kreisl TN, Fine HA, Figg WD. A novel uHPLC-MS/MS method for the quantitation of AZD7451 (AZ12607092) in human plasma. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 942: 107-12. PMID 24239935 DOI: 10.1016/J.Jchromb.2013.10.023  0.279
2010 Billups J, Jones C, Jackson TL, Ablordeppey SY, Spencer SD. Simultaneous RP-HPLC-DAD quantification of bromocriptine, haloperidol and its diazepane structural analog in rat plasma with droperidol as internal standard for application to drug-interaction pharmacokinetics. Biomedical Chromatography : Bmc. 24: 699-705. PMID 19908205 DOI: 10.1002/Bmc.1349  0.275
2012 Spencer SD, Figg WD, Rosen LS, Gordon MS, Hurwitz H, Wong MK, Goldman JW, Mendelson DS, Adams BJ, Alvarez D, Seon BK, Theuer CP, Leigh BR. Dose-specific clearance of TRC105 (anti-CD105 antibody) in advanced solid tumor patients. Journal of Clinical Oncology. 30: 3042-3042. DOI: 10.1200/Jco.2012.30.15_Suppl.3042  0.269
2012 Chen X, Peer CJ, Alfaro R, Tian T, Spencer SD, Figg WD. Quantification of irinotecan, SN38, and SN38G in human and porcine plasma by ultra high-performance liquid chromatography-tandem mass spectrometry and its application to hepatic chemoembolization. Journal of Pharmaceutical and Biomedical Analysis. 62: 140-8. PMID 22305081 DOI: 10.1016/J.Jpba.2012.01.008  0.266
2009 Yang LX, Huang KX, Li HB, Gong JX, Wang F, Feng YB, Tao QF, Wu YH, Li XK, Wu XM, Zeng S, Spencer S, Zhao Y, Qu J. Design, synthesis, and examination of neuron protective properties of alkenylated and amidated dehydro-silybin derivatives. Journal of Medicinal Chemistry. 52: 7732-52. PMID 19673490 DOI: 10.1021/Jm900735P  0.263
2013 Kelly RJ, Thomas A, Rajan A, Chun G, Lopez-Chavez A, Szabo E, Spencer S, Carter CA, Guha U, Khozin S, Poondru S, Van Sant C, Keating A, Steinberg SM, Figg W, et al. A phase I/II study of sepantronium bromide (YM155, survivin suppressor) with paclitaxel and carboplatin in patients with advanced non-small-cell lung cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 24: 2601-6. PMID 23857959 DOI: 10.1093/Annonc/Mdt249  0.261
2013 Peer CJ, Rao M, Spencer SD, Shahbazi S, Steeg PS, Schrump DS, Figg WD. A rapid ultra HPLC-MS/MS method for the quantitation and pharmacokinetic analysis of 3-deazaneplanocin A in mice. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 927: 142-6. PMID 23352636 DOI: 10.1016/J.Jchromb.2013.01.003  0.256
2011 Kummar S, Raffeld M, Juwara L, Horneffer Y, Strassberger A, Allen D, Steinberg SM, Rapisarda A, Spencer SD, Figg WD, Chen X, Turkbey IB, Choyke P, Murgo AJ, Doroshow JH, et al. Multihistology, target-driven pilot trial of oral topotecan as an inhibitor of hypoxia-inducible factor-1α in advanced solid tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 5123-31. PMID 21673063 DOI: 10.1158/1078-0432.Ccr-11-0682  0.252
2013 Dahut WL, Madan RA, Karakunnel JJ, Adelberg D, Gulley JL, Turkbey IB, Chau CH, Spencer SD, Mulquin M, Wright J, Parnes HL, Steinberg SM, Choyke PL, Figg WD. Phase II clinical trial of cediranib in patients with metastatic castration-resistant prostate cancer. Bju International. 111: 1269-80. PMID 23419134 DOI: 10.1111/J.1464-410X.2012.11667.X  0.252
2012 Peer CJ, Spencer SD, VanDenBerg DA, Pacanowski MA, Horenstein RB, Figg WD. A sensitive and rapid ultra HPLC-MS/MS method for the simultaneous detection of clopidogrel and its derivatized active thiol metabolite in human plasma. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 880: 132-9. PMID 22169056 DOI: 10.1016/J.Jchromb.2011.11.029  0.251
2012 Rosen LS, Hurwitz HI, Wong MK, Goldman J, Mendelson DS, Figg WD, Spencer S, Adams BJ, Alvarez D, Seon BK, Theuer CP, Leigh BR, Gordon MS. A phase I first-in-human study of TRC105 (Anti-Endoglin Antibody) in patients with advanced cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 4820-9. PMID 22767667 DOI: 10.1158/1078-0432.Ccr-12-0098  0.246
2017 Backman JD, O'Connell JR, Tanner K, Peer CJ, Figg WD, Spencer SD, Mitchell BD, Shuldiner AR, Yerges-Armstrong LM, Horenstein RB, Lewis JP. Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response. Pharmacogenetics and Genomics. PMID 28207573 DOI: 10.1097/Fpc.0000000000000272  0.246
2012 Patel AR, Spencer SD, Chougule MB, Safe S, Singh M. Pharmacokinetic evaluation and in vitro-in vivo correlation (IVIVC) of novel methylene-substituted 3,3' diindolylmethane (DIM). European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 46: 8-16. PMID 22342559 DOI: 10.1016/J.Ejps.2012.01.012  0.242
2013 Figg WD, Chau CH, Madan RA, Gulley JL, Gao R, Sissung TM, Spencer S, Beatson M, Aragon-Ching J, Steinberg SM, Dahut WL. Phase II study of satraplatin and prednisone in patients with metastatic castration-resistant prostate cancer: a pharmacogenetic assessment of outcome and toxicity. Clinical Genitourinary Cancer. 11: 229-37. PMID 23684781 DOI: 10.1016/J.Clgc.2013.04.007  0.242
2012 Price DK, Troutman SM, Sissung TM, Cropp C, Venzon DJ, Spencer SD, Figg WD. Abstract B29: A meta-analysis of racial disparities in the association between 8q24 and prostate cancer risk Cancer Research. 72: B29-B29. DOI: 10.1158/1538-7445.Prca2012-B29  0.241
2012 Rajan A, Carter CA, Kelly RJ, Gutierrez M, Kummar S, Szabo E, Yancey MA, Ji J, Mannargudi B, Woo S, Spencer S, Figg WD, Giaccone G. A phase I combination study of olaparib with cisplatin and gemcitabine in adults with solid tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 2344-51. PMID 22371451 DOI: 10.1158/1078-0432.Ccr-11-2425  0.238
2013 Gao R, Reece KM, Sissung T, Fu SH, Venzon DJ, Reed E, Spencer SD, Price DK, Figg WD. Are race-specific ERCC1 haplotypes in melanoma cases versus controls related to the predictive and prognostic value of ERCC1 N118N? Bmj Open. 3. PMID 23293248 DOI: 10.1136/Bmjopen-2012-002030  0.226
2012 Sissung TM, Reece KM, Spencer S, Figg WD. Contribution of the OATP1B subfamily to cancer biology and treatment. Clinical Pharmacology and Therapeutics. 92: 658-60. PMID 23010650 DOI: 10.1038/Clpt.2012.127  0.221
2013 Lewis JP, Horenstein RB, Ryan K, O'Connell JR, Gibson Q, Mitchell BD, Tanner K, Chai S, Bliden KP, Tantry US, Peer CJ, Figg WD, Spencer SD, Pacanowski MA, Gurbel PA, et al. The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response. Pharmacogenetics and Genomics. 23: 1-8. PMID 23111421 DOI: 10.1097/Fpc.0B013E32835Aa8A2  0.22
2012 Troutman SM, Sissung TM, Cropp CD, Venzon DJ, Spencer SD, Price DK, Figg WD. Association between variants on 8q24 and prostate cancer: A review and meta-analysis. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 28. PMID 27967851 DOI: 10.1200/Jco.2012.30.5_Suppl.28  0.219
2012 Peng F, Tao Q, Wu X, Dou H, Spencer S, Mang C, Xu L, Sun L, Zhao Y, Li H, Zeng S, Liu G, Hao X. Cytotoxic, cytoprotective and antioxidant effects of isolated phenolic compounds from fresh ginger. Fitoterapia. 83: 568-85. PMID 22248534 DOI: 10.1016/J.Fitote.2011.12.028  0.218
2012 Troutman SM, Sissung TM, Cropp CD, Venzon DJ, Spencer SD, Adesunloye BA, Huang X, Karzai FH, Price DK, Figg WD. Racial disparities in the association between variants on 8q24 and prostate cancer: a systematic review and meta-analysis. The Oncologist. 17: 312-20. PMID 22382457 DOI: 10.1634/Theoncologist.2011-0315  0.216
2012 Baird K, Booher S, Comis L, Joe G, Steinberg S, Spencer S, Figg W, Takebe N, Pavletic S, Cowen E. Phase II Pilot Study of Imatinib Mesylate for the Treatment of Severe Sclerotic Skin Chronic Graft Versus Host Disease (ScGVHD) Biology of Blood and Marrow Transplantation. 18: S208. DOI: 10.1016/J.Bbmt.2011.12.018  0.202
2013 Waldmann TA, Conlon KC, Stewart DM, Worthy TA, Janik JE, Fleisher TA, Albert PS, Figg WD, Spencer SD, Raffeld M, Decker JR, Goldman CK, Bryant BR, Petrus MN, Creekmore SP, et al. Phase 1 trial of IL-15 trans presentation blockade using humanized Mikβ1 mAb in patients with T-cell large granular lymphocytic leukemia. Blood. 121: 476-84. PMID 23212516 DOI: 10.1182/Blood-2012-08-450585  0.198
2016 Andey T, Patel A, Marepally S, Chougule M, Spencer SD, Rishi AK, Singh M. Formulation, Pharmacokinetic, and Efficacy Studies of Mannosylated Self-Emulsifying Solid Dispersions of Noscapine. Plos One. 11: e0146804. PMID 26757437 DOI: 10.1371/Journal.Pone.0146804  0.196
2011 Li H, Qiang F, Yang Z, Spencer SD, Cui X, Wu X, Chen X. Hepatitis B virus with pre-S2 deletion is more prevalent in hepatocellular carcinoma than in chronic active hepatitis and asymptomatic carriers. Acta Virologica. 55: 183-5. PMID 21692570 DOI: 10.4149/Av_2011_02_183  0.176
2023 Bagde A, Dev S, Madhavi K Sriram L, Spencer SD, Kalvala A, Nathani A, Salau O, Mosley-Kellum K, Dalvaigari H, Rajaraman S, Kundu A, Singh M. Biphasic burst and sustained transdermal delivery in vivo using an AI-optimized 3D-printed MN patch. International Journal of Pharmaceutics. 122647. PMID 36754185 DOI: 10.1016/j.ijpharm.2023.122647  0.12
2023 Mosley-Kellum K, Bagde A, Spencer S, Dev S, Singh M. Development of 3D DLP Printed Sustained Release Ibuprofen Tablets and Their Pharmacokinetic Evaluation in Rats. Aaps Pharmscitech. 24: 88. PMID 36977867 DOI: 10.1208/s12249-023-02544-5  0.118
2012 Spencer S, Marini BL, Figg WD. Novel approaches in the pharmacotherapy of skeletal-related events in metastatic castrate-resistant prostate cancer. Anticancer Research. 32: 2391-8. PMID 22753695  0.083
2012 Troutman SM, Sissung TM, Cropp CD, Venzon DJ, Spencer SD, Price DK, Figg WD. Association between variants on 8q24 and prostate cancer: A review and meta-analysis. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 28. PMID 28142910 DOI: 10.1200/jco.2012.30.5_suppl.28  0.076
2020 Morrow K, Young KA, Spencer S, Medina ES, Marziale MA, Sanchez A, Bourgeois JA. Utility of oxcarbazepine in the treatment of childhood and adolescent psychiatric symptoms. Proceedings (Baylor University. Medical Center). 34: 34-39. PMID 33456141 DOI: 10.1080/08998280.2020.1826259  0.044
2020 North RB, Parihar HS, Spencer SD, Spalding AF, Shipley J. Cost-Effectiveness Model Shows Superiority of Wireless Spinal Cord Stimulation Implantation Without a Separate Trial. Neuromodulation : Journal of the International Neuromodulation Society. PMID 32065696 DOI: 10.1111/ner.13102  0.027
2012 Li H, Spencer SD, Lian L, Zhang Z, Lu P. Phylogenetic analysis of the nucleoprotein gene of measles viruses prevalent in Nantong, Jiangsu Province, China, during 2010. Epidemiology and Infection. 140: 1607-11. PMID 22117136 DOI: 10.1017/S0950268811002433  0.026
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