| Year |
Citation |
Score |
| 2023 |
Parsons AJ, Stein KR, Atanasoff KE, Ophir SI, Casado JP, Tortorella D. The CD46 ectodomain participates in human cytomegalovirus infection of epithelial cells. The Journal of General Virology. 104. PMID 37668349 DOI: 10.1099/jgv.0.001892 |
0.305 |
|
| 2023 |
Zhao N, Ho JSY, Meng F, Zheng S, Kurland AP, Tian L, Rea-Moreno M, Song X, Seo JS, Kaniskan HÜ, Te Velthuis AJW, Tortorella D, Chen YW, Johnson JR, Jin J, et al. Generation of host-directed and virus-specific antivirals using targeted protein degradation promoted by small molecules and viral RNA mimics. Cell Host & Microbe. PMID 37339625 DOI: 10.1016/j.chom.2023.05.030 |
0.313 |
|
| 2022 |
Parsons AJ, Ophir SI, Gardner TJ, Paredes JC, Stein KR, Kwasny SM, Cardinale SC, Torhan M, Prichard MN, James SH, Atanasoff KE, G-Dayanandan N, Bowlin TL, Opperman TJ, Tortorella D. Investigating N-arylpyrimidinamine (NAPA) compounds as early-stage inhibitors against human cytomegalovirus. Antiviral Research. 209: 105474. PMID 36511318 DOI: 10.1016/j.antiviral.2022.105474 |
0.326 |
|
| 2021 |
Parsons AJ, Cohen T, Schwarz TM, Stein KR, Ophir SI, Casado JP, Tortorella D. Valspodar limits human cytomegalovirus infection and dissemination. Antiviral Research. 105124. PMID 34197862 DOI: 10.1016/j.antiviral.2021.105124 |
0.377 |
|
| 2019 |
Stein KR, Gardner TJ, Hernandez RE, Kraus TA, Duty JA, Ubarretxena-Belandia I, Moran TM, Tortorella D. CD46 facilitates entry and dissemination of human cytomegalovirus. Nature Communications. 10: 2699. PMID 31221976 DOI: 10.1038/S41467-019-10587-1 |
0.44 |
|
| 2019 |
Behzadi MA, Stein KR, Bermúdez-González MC, Simon V, Nachbagauer R, Tortorella D. An Influenza Virus Hemagglutinin-Based Vaccine Platform Enables the Generation of Epitope Specific Human Cytomegalovirus Antibodies. Vaccines. 7. PMID 31207917 DOI: 10.3390/Vaccines7020051 |
0.389 |
|
| 2018 |
Møller R, Schwarz TM, Noriega VM, Panis M, Sachs D, Tortorella D, tenOever BR. miRNA-mediated targeting of human cytomegalovirus reveals biological host and viral targets of IE2. Proceedings of the National Academy of Sciences of the United States of America. PMID 29339472 DOI: 10.1073/Pnas.1719036115 |
0.807 |
|
| 2017 |
Bardina SV, Bunduc P, Tripathi S, Duehr J, Frere JJ, Brown JA, Nachbagauer R, Foster GA, Krysztof D, Tortorella D, Stramer SL, García-Sastre A, Krammer F, Lim JK. Enhancement of Zika virus pathogenesis by preexisting antiflavivirus immunity. Science (New York, N.Y.). PMID 28360135 DOI: 10.1126/Science.Aal4365 |
0.389 |
|
| 2016 |
Gardner TJ, Stein KR, Duty JA, Schwarz TM, Noriega VM, Kraus T, Moran TM, Tortorella D. Functional screening for anti-CMV biologics identifies a broadly neutralizing epitope of an essential envelope protein. Nature Communications. 7: 13627. PMID 27966523 DOI: 10.1038/Ncomms13627 |
0.81 |
|
| 2016 |
Cohen T, Schwarz TM, Vigant F, Gardner TJ, Hernandez RE, Lee B, Tortorella D. The Microtubule Inhibitor Podofilox Inhibits an Early Entry Step of Human Cytomegalovirus. Viruses. 8. PMID 27783035 DOI: 10.3390/V8100295 |
0.477 |
|
| 2016 |
Schwarz MC, Sourisseau M, Espino MM, Gray ES, Chambers MT, Tortorella D, Evans MJ. Rescue of the 1947 Zika Virus Prototype Strain with a Cytomegalovirus Promoter-Driven cDNA Clone. Msphere. 1. PMID 27704051 DOI: 10.1128/mSphere.00246-16 |
0.339 |
|
| 2016 |
Cohen T, Williams JD, Opperman TJ, Sanchez R, Lurain NS, Tortorella D. Convallatoxin-induced reduction of methionine import effectively inhibits human cytomegalovirus infection and replication. Journal of Virology. PMID 27654292 DOI: 10.1128/Jvi.01050-16 |
0.422 |
|
| 2016 |
Gardner TJ, Tortorella D. Virion Glycoprotein-Mediated Immune Evasion by Human Cytomegalovirus: a Sticky Virus Makes a Slick Getaway. Microbiology and Molecular Biology Reviews : Mmbr. 80: 663-77. PMID 27307580 DOI: 10.1128/Mmbr.00018-16 |
0.506 |
|
| 2016 |
Gardner TJ, Hernandez RE, Noriega VM, Tortorella D. Human cytomegalovirus gH stability and trafficking are regulated by ER-associated degradation and transmembrane architecture. Scientific Reports. 6: 23692. PMID 27026399 DOI: 10.1038/Srep23692 |
0.812 |
|
| 2016 |
Heaton NS, Moshkina N, Fenouil R, Gardner TJ, Aguirre S, Shah PS, Zhao N, Manganaro L, Hultquist JF, Noel J, Sachs DH, Hamilton J, Leon PE, Chawdury A, Tripathi S, ... ... Tortorella D, et al. Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection. Immunity. 44: 46-58. PMID 26789921 DOI: 10.1016/J.Immuni.2015.12.017 |
0.469 |
|
| 2016 |
Heaton NS, Moshkina N, Fenouil R, Gardner TJ, Aguirre S, Shah PS, Zhao N, Manganaro L, Hultquist JF, Noel J, Sachs D, Hamilton J, Leon PE, Chawdury A, Tripathi S, ... ... Tortorella D, et al. Corrections to Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection. (Immunity 44, 46-58, January 19, 2016) Immunity. 44: 438. DOI: 10.1016/J.Immuni.2016.01.016 |
0.416 |
|
| 2015 |
Gardner TJ, Cohen T, Redmann V, Lau Z, Felsenfeld D, Tortorella D. Development of a high-content screen for the identification of inhibitors directed against the early steps of the cytomegalovirus infectious cycle. Antiviral Research. 113: 49-61. PMID 25446405 DOI: 10.1016/J.Antiviral.2014.10.011 |
0.794 |
|
| 2014 |
Noriega VM, Haye KK, Kraus TA, Kowalsky SR, Ge Y, Moran TM, Tortorella D. Human cytomegalovirus modulates monocyte-mediated innate immune responses during short-term experimental latency in vitro. Journal of Virology. 88: 9391-405. PMID 24920803 DOI: 10.1128/Jvi.00934-14 |
0.808 |
|
| 2014 |
Noriega VM, Gardner TJ, Redmann V, Bongers G, Lira SA, Tortorella D. Human cytomegalovirus US28 facilitates cell-to-cell viral dissemination. Viruses. 6: 1202-18. PMID 24625810 DOI: 10.3390/V6031202 |
0.773 |
|
| 2014 |
Redmann V, Gardner T, Lau Z, Morohashi K, Felsenfeld D, Tortorella D. Novel class of potential therapeutics that target ricin retrograde translocation. Toxins. 6: 33-53. PMID 24366208 DOI: 10.3390/Toxins6010033 |
0.778 |
|
| 2013 |
Miller MS, Gardner TJ, Krammer F, Aguado LC, Tortorella D, Basler CF, Palese P. Neutralizing antibodies against previously encountered influenza virus strains increase over time: a longitudinal analysis. Science Translational Medicine. 5: 198ra107. PMID 23946196 DOI: 10.1126/Scitranslmed.3006637 |
0.357 |
|
| 2013 |
Gardner TJ, Bolovan-Fritts C, Teng MW, Redmann V, Kraus TA, Sperling R, Moran T, Britt W, Weinberger LS, Tortorella D. Development of a high-throughput assay to measure the neutralization capability of anti-cytomegalovirus antibodies. Clinical and Vaccine Immunology : Cvi. 20: 540-50. PMID 23389931 DOI: 10.1128/Cvi.00644-12 |
0.808 |
|
| 2012 |
Noriega VM, Hesse J, Gardner TJ, Besold K, Plachter B, Tortorella D. Human cytomegalovirus US3 modulates destruction of MHC class I molecules. Molecular Immunology. 51: 245-53. PMID 22497807 DOI: 10.1016/J.Molimm.2012.03.024 |
0.825 |
|
| 2012 |
Noriega V, Redmann V, Gardner T, Tortorella D. Diverse immune evasion strategies by human cytomegalovirus. Immunologic Research. 54: 140-51. PMID 22454101 DOI: 10.1007/S12026-012-8304-8 |
0.763 |
|
| 2011 |
Redmann V, Oresic K, Tortorella LL, Cook JP, Lord M, Tortorella D. Dislocation of ricin toxin A chains in human cells utilizes selective cellular factors. The Journal of Biological Chemistry. 286: 21231-8. PMID 21527639 DOI: 10.1074/Jbc.M111.234708 |
0.785 |
|
| 2010 |
Bongers G, Maussang D, Muniz LR, Noriega VM, Fraile-Ramos A, Barker N, Marchesi F, Thirunarayanan N, Vischer HF, Qin L, Mayer L, Harpaz N, Leurs R, Furtado GC, Clevers H, ... Tortorella D, et al. The cytomegalovirus-encoded chemokine receptor US28 promotes intestinal neoplasia in transgenic mice. The Journal of Clinical Investigation. 120: 3969-78. PMID 20978345 DOI: 10.1172/Jci42563 |
0.783 |
|
| 2010 |
Ng CL, Oresic K, Tortorella D. TRAM1 is involved in disposal of ER membrane degradation substrates. Experimental Cell Research. 316: 2113-22. PMID 20430023 DOI: 10.1016/J.Yexcr.2010.04.010 |
0.73 |
|
| 2009 |
Oresic K, Ng CL, Tortorella D. TRAM1 participates in human cytomegalovirus US2- and US11-mediated dislocation of an endoplasmic reticulum membrane glycoprotein. The Journal of Biological Chemistry. 284: 5905-14. PMID 19121997 DOI: 10.1074/Jbc.M807568200 |
0.782 |
|
| 2009 |
Noriega VM, Tortorella D. Human cytomegalovirus-encoded immune modulators partner to downregulate major histocompatibility complex class I molecules. Journal of Virology. 83: 1359-67. PMID 19004944 DOI: 10.1128/Jvi.01324-08 |
0.828 |
|
| 2009 |
Oresic K, Mueller B, Tortorella D. Cln6 mutants associated with neuronal ceroid lipofuscinosis are degraded in a proteasome-dependent manner. Bioscience Reports. 29: 173-81. PMID 18811591 DOI: 10.1042/Bsr20080143 |
0.348 |
|
| 2008 |
Oresic K, Tortorella D. Endoplasmic reticulum chaperones participate in human cytomegalovirus US2-mediated degradation of class I major histocompatibility complex molecules. The Journal of General Virology. 89: 1122-30. PMID 18420789 DOI: 10.1099/Vir.0.83516-0 |
0.556 |
|
| 2008 |
Noriega VM, Tortorella D. A bipartite trigger for dislocation directs the proteasomal degradation of an endoplasmic reticulum membrane glycoprotein. The Journal of Biological Chemistry. 283: 4031-43. PMID 18086679 DOI: 10.1074/Jbc.M706283200 |
0.8 |
|
| 2007 |
Baker BM, Tortorella D. Dislocation of an endoplasmic reticulum membrane glycoprotein involves the formation of partially dislocated ubiquitinated polypeptides. The Journal of Biological Chemistry. 282: 26845-56. PMID 17650499 DOI: 10.1074/Jbc.M704315200 |
0.802 |
|
| 2006 |
Loureiro J, Lilley BN, Spooner E, Noriega V, Tortorella D, Ploegh HL. Signal peptide peptidase is required for dislocation from the endoplasmic reticulum. Nature. 441: 894-7. PMID 16738546 DOI: 10.1038/Nature04830 |
0.804 |
|
| 2006 |
Oresic K, Noriega V, Andrews L, Tortorella D. A structural determinant of human cytomegalovirus US2 dictates the down-regulation of class I major histocompatibility molecules. The Journal of Biological Chemistry. 281: 19395-406. PMID 16687410 DOI: 10.1074/Jbc.M601026200 |
0.811 |
|
| 2005 |
Fiebiger E, Tortorella D, Jouvin MH, Kinet JP, Ploegh HL. Cotranslational endoplasmic reticulum assembly of FcεRI controls the formation of functional IgE-binding receptors Journal of Experimental Medicine. 201: 267-277. PMID 15642744 DOI: 10.1084/Jem.20041384 |
0.366 |
|
| 2004 |
Fiebiger E, Hirsch C, Vyas JM, Gordon E, Ploegh HL, Tortorella D. Dissection of the dislocation pathway for type I membrane proteins with a new small molecule inhibitor, eeyarestatin. Molecular Biology of the Cell. 15: 1635-46. PMID 14767067 DOI: 10.1091/Mbc.E03-07-0506 |
0.48 |
|
| 2004 |
Blom D, Hirsch C, Stern P, Tortorella D, Ploegh HL. A glycosylated type I membrane protein becomes cytosolic when peptide: N-glycanase is compromised. The Embo Journal. 23: 650-8. PMID 14749736 DOI: 10.1038/Sj.Emboj.7600090 |
0.445 |
|
| 2003 |
Lilley BN, Tortorella D, Ploegh HL. Dislocation of a type I membrane protein requires interactions between membrane-spanning segments within the lipid bilayer. Molecular Biology of the Cell. 14: 3690-8. PMID 12972557 DOI: 10.1091/Mbc.E03-03-0192 |
0.455 |
|
| 2003 |
Furman MH, Loureiro J, Ploegh HL, Tortorella D. Ubiquitinylation of the cytosolic domain of a type I membrane protein is not required to initiate its dislocation from the endoplasmic reticulum. The Journal of Biological Chemistry. 278: 34804-11. PMID 12832421 DOI: 10.1074/Jbc.M300913200 |
0.466 |
|
| 2003 |
Tirosh B, Furman MH, Tortorella D, Ploegh HL. Protein unfolding is not a prerequisite for endoplasmic reticulum-to-cytosol dislocation. The Journal of Biological Chemistry. 278: 6664-72. PMID 12482753 DOI: 10.1074/Jbc.M210158200 |
0.418 |
|
| 2002 |
Furman MH, Dey N, Tortorella D, Ploegh HL. The human cytomegalovirus US10 gene product delays trafficking of major histocompatibility complex class I molecules. Journal of Virology. 76: 11753-6. PMID 12388737 DOI: 10.1128/Jvi.76.22.11753-11756.2002 |
0.47 |
|
| 2002 |
Rehm A, Engelsberg A, Tortorella D, Körner IJ, Lehmann I, Ploegh HL, Höpken UE. Human cytomegalovirus gene products US2 and US11 differ in their ability to attack major histocompatibility class I heavy chains in dendritic cells. Journal of Virology. 76: 5043-50. PMID 11967320 DOI: 10.1128/Jvi.76.10.5043-5050.2002 |
0.508 |
|
| 2002 |
Fiebiger E, Story C, Ploegh HL, Tortorella D. Visualization of the ER-to-cytosol dislocation reaction of a type I membrane protein. The Embo Journal. 21: 1041-53. PMID 11867532 DOI: 10.1093/Emboj/21.5.1041 |
0.511 |
|
| 2002 |
Gewurz BE, Ploegh HL, Tortorella D. US2, a human cytomegalovirus-encoded type I membrane protein, contains a non-cleavable amino-terminal signal peptide. The Journal of Biological Chemistry. 277: 11306-13. PMID 11790769 DOI: 10.1074/Jbc.M107904200 |
0.402 |
|
| 2002 |
Furman MH, Ploegh HL, Tortorella D. Membrane-specific, host-derived factors are required for US2- and US11-mediated degradation of major histocompatibility complex class I molecules. The Journal of Biological Chemistry. 277: 3258-67. PMID 11717308 DOI: 10.1074/Jbc.M109765200 |
0.489 |
|
| 2001 |
Kessler BM, Tortorella D, Altun M, Kisselev AF, Fiebiger E, Hekking BG, Ploegh HL, Overkleeft HS. Extended peptide-based inhibitors efficiently target the proteasome and reveal overlapping specificities of the catalytic beta-subunits. Chemistry & Biology. 8: 913-29. PMID 11564559 DOI: 10.1016/S1074-5521(01)00069-2 |
0.314 |
|
| 2001 |
Gewurz BE, Gaudet R, Tortorella D, Wang EW, Ploegh HL. Virus subversion of immunity: a structural perspective. Current Opinion in Immunology. 13: 442-50. PMID 11498300 DOI: 10.1016/S0952-7915(00)00239-9 |
0.407 |
|
| 2001 |
Gewurz BE, Gaudet R, Tortorella D, Wang EW, Ploegh HL, Wiley DC. Antigen presentation subverted: Structure of the human cytomegalovirus protein US2 bound to the class I molecule HLA-A2. Proceedings of the National Academy of Sciences of the United States of America. 98: 6794-9. PMID 11391001 DOI: 10.1073/Pnas.121172898 |
0.463 |
|
| 2001 |
Gewurz BE, Wang EW, Tortorella D, Schust DJ, Ploegh HL. Human cytomegalovirus US2 endoplasmic reticulum-lumenal domain dictates association with major histocompatibility complex class I in a locus-specific manner. Journal of Virology. 75: 5197-204. PMID 11333901 DOI: 10.1128/Jvi.75.11.5197-5204.2001 |
0.45 |
|
| 2001 |
Rehm A, Stern P, Ploegh HL, Tortorella D. Signal peptide cleavage of a type I membrane protein, HCMV US11, is dependent on its membrane anchor. The Embo Journal. 20: 1573-82. PMID 11285222 DOI: 10.1093/Emboj/20.7.1573 |
0.333 |
|
| 2000 |
Tortorella D, Gewurz B, Schust D, Furman M, Ploegh H. Down-regulation of MHC class I antigen presentation by HCMV; lessons for tumor immunology. Immunological Investigations. 29: 97-100. PMID 10854174 DOI: 10.3109/08820130009062289 |
0.474 |
|
| 2000 |
Tortorella D, Gewurz BE, Furman MH, Schust DJ, Ploegh HL. Viral subversion of the immune system. Annual Review of Immunology. 18: 861-926. PMID 10837078 DOI: 10.1146/Annurev.Immunol.18.1.861 |
0.347 |
|
| 1999 |
Schust DJ, Tortorella D, Ploegh HL. Viral immunoevasive strategies and trophoblast class I major histocompatibility complex antigens. Journal of Reproductive Immunology. 43: 243-51. PMID 10479060 DOI: 10.1016/S0165-0378(99)00024-8 |
0.414 |
|
| 1999 |
Schust DJ, Tortorella D, Ploegh HL. HLA-G and HLA-C at the feto-maternal interface: lessons learned from pathogenic viruses. Seminars in Cancer Biology. 9: 37-46. PMID 10092549 DOI: 10.1006/Scbi.1998.0106 |
0.417 |
|
| 1998 |
Schust DJ, Tortorella D, Seebach J, Phan C, Ploegh HL. Trophoblast class I major histocompatibility complex (MHC) products are resistant to rapid degradation imposed by the human cytomegalovirus (HCMV) gene products US2 and US11. The Journal of Experimental Medicine. 188: 497-503. PMID 9687527 DOI: 10.1084/Jem.188.3.497 |
0.474 |
|
| 1998 |
Tortorella D, Story CM, Huppa JB, Wiertz EJ, Jones TR, Bacik I, Bennink JR, Yewdell JW, Ploegh HL. Dislocation of type I membrane proteins from the ER to the cytosol is sensitive to changes in redox potential. The Journal of Cell Biology. 142: 365-76. PMID 9679137 DOI: 10.1083/Jcb.142.2.365 |
0.4 |
|
| 1997 |
Wiertz E, Hill A, Tortorella D, Ploegh H. Cytomegaloviruses use multiple mechanisms to elude the host immune response. Immunology Letters. 57: 213-6. PMID 9232454 DOI: 10.1016/S0165-2478(97)00073-4 |
0.379 |
|
| 1997 |
Bogyo M, McMaster JS, Gaczynska M, Tortorella D, Goldberg AL, Ploegh H. Covalent modification of the active site threonine of proteasomal β subunits and the Escherichia coli homolog HsIV by a new class of inhibitors Proceedings of the National Academy of Sciences of the United States of America. 94: 6629-6634. PMID 9192616 DOI: 10.1073/Pnas.94.13.6629 |
0.311 |
|
| 1997 |
Wiertz EJ, Tortorella D, Bogyo M, Yu J, Galocha B, Mothes W, Jones TR, Rapoport TA, Ploegh HL. Cytomegalovirus uses multiple strategies to interfere with MHC class I-restricted antigen presentation Immunology Letters. 56: 189. DOI: 10.1016/S0165-2478(97)85759-8 |
0.405 |
|
| 1996 |
Wiertz EJ, Tortorella D, Bogyo M, Yu J, Mothes W, Jones TR, Rapoport TA, Ploegh HL. Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction. Nature. 384: 432-8. PMID 8945469 DOI: 10.1038/384432A0 |
0.47 |
|
| 1993 |
Tortorella D, Ulbrandt ND, London E. Simple centrifugation method for efficient pelleting of both small and large unilamellar vesicles that allows convenient measurement of protein binding. Biochemistry. 32: 9181-8. PMID 8369285 DOI: 10.1021/Bi00086A025 |
0.305 |
|
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