| Year |
Citation |
Score |
| 2021 |
Zhang H, Veira J, Bauer ST, Yip C, Singh U. RISC in Entamoeba histolytica: Identification of a Protein-Protein Interaction Network for the RNA Interference Pathway in a Deep-Branching Eukaryote. Mbio. e0154021. PMID 34488447 DOI: 10.1128/mBio.01540-21 |
0.3 |
|
| 2020 |
Kangussu-Marcolino MM, Morgado P, Manna D, Yee H, Singh U. Development of a CRISPR/Cas9 system in Entamoeba histolytica: proof of concept. International Journal For Parasitology. PMID 33264648 DOI: 10.1016/j.ijpara.2020.09.005 |
0.393 |
|
| 2020 |
Manna D, Lozano-Amado D, Ehrenkaufer G, Singh U. The NAD Responsive Transcription Factor ERM-BP Functions Downstream of Cellular Aggregation and Is an Early Regulator of Development and Heat Shock Response in . Frontiers in Cellular and Infection Microbiology. 10: 363. PMID 32766170 DOI: 10.3389/Fcimb.2020.00363 |
0.354 |
|
| 2020 |
Sharma M, Morgado P, Zhang H, Ehrenkaufer G, Manna D, Singh U. Characterization of extracellular vesicles from identifies roles in intercellular communication that regulates parasite growth and development. Infection and Immunity. PMID 32719158 DOI: 10.1128/Iai.00349-20 |
0.349 |
|
| 2020 |
Ehrenkaufer G, Li P, Stebbins EE, Kangussu-Marcolino MM, Debnath A, White CV, Moser MS, DeRisi J, Gisselberg J, Yeh E, Wang SC, Company AH, Monti L, Caffrey CR, Huston CD, ... ... Singh U, et al. Identification of anisomycin, prodigiosin and obatoclax as compounds with broad-spectrum anti-parasitic activity. Plos Neglected Tropical Diseases. 14: e0008150. PMID 32196500 DOI: 10.1371/Journal.Pntd.0008150 |
0.311 |
|
| 2019 |
Manna D, Singh U. Nuclear Factor Y (NF-Y) Modulates Encystation in via Stage-Specific Expression of the NF-YB and NF-YC Subunits. Mbio. 10. PMID 31213550 DOI: 10.1128/Mbio.00737-19 |
0.325 |
|
| 2018 |
Manna D, Lentz CS, Ehrenkaufer GM, Suresh S, Bhat A, Singh U. An NAD-dependent novel transcription factor controls stage conversion in . Elife. 7. PMID 30375973 DOI: 10.7554/Elife.37912 |
0.344 |
|
| 2018 |
Ehrenkaufer GM, Suresh S, Solow-Cordero D, Singh U. High-Throughput Screening of Identifies Compounds Which Target Both Life Cycle Stages and Which Are Effective Against Metronidazole Resistant Parasites. Frontiers in Cellular and Infection Microbiology. 8: 276. PMID 30175074 DOI: 10.3389/Fcimb.2018.00276 |
0.3 |
|
| 2016 |
Morgado P, Manna D, Singh U. Recent advances in Entamoeba biology: RNA interference, drug discovery, and gut microbiome. F1000research. 5: 2578. PMID 27853522 DOI: 10.12688/F1000Research.9241.1 |
0.38 |
|
| 2016 |
Suresh S, Ehrenkaufer G, Zhang H, Singh U. Development of RNAi trigger-mediated gene silencing in Entamoeba invadens. Infection and Immunity. PMID 26787723 DOI: 10.1128/Iai.01161-15 |
0.47 |
|
| 2015 |
Khalil MI, Foda BM, Suresh S, Singh U. Technical advances in trigger-induced RNA interference gene silencing in the parasite Entamoeba histolytica. International Journal For Parasitology. PMID 26747561 DOI: 10.1016/J.Ijpara.2015.11.004 |
0.464 |
|
| 2015 |
Zhang H, Ehrenkaufer GM, Manna D, Hall N, Singh U. High Throughput Sequencing of Entamoeba 27nt Small RNA Population Reveals Role in Permanent Gene Silencing But No Effect on Regulating Gene Expression Changes during Stage Conversion, Oxidative, or Heat Shock Stress. Plos One. 10: e0134481. PMID 26248204 DOI: 10.1371/Journal.Pone.0134481 |
0.391 |
|
| 2015 |
Pompey JM, Foda B, Singh U. A Single RNaseIII Domain Protein from Entamoeba histolytica Has dsRNA Cleavage Activity and Can Help Mediate RNAi Gene Silencing in a Heterologous System. Plos One. 10: e0133740. PMID 26230096 DOI: 10.1371/Journal.Pone.0133740 |
0.33 |
|
| 2015 |
Foda BM, Singh U. Dimethylated H3K27 Is a Repressive Epigenetic Histone Mark in the Protist Entamoeba histolytica and Is Significantly Enriched in Genes Silenced via the RNAi Pathway. The Journal of Biological Chemistry. 290: 21114-30. PMID 26149683 DOI: 10.1074/Jbc.M115.647263 |
0.375 |
|
| 2015 |
Rastew E, Morf L, Singh U. Entamoeba histolytica rhomboid protease 1 has a role in migration and motility as validated by two independent genetic approaches. Experimental Parasitology. 154: 33-42. PMID 25889553 DOI: 10.1016/J.Exppara.2015.04.004 |
0.461 |
|
| 2014 |
Pompey JM, Morf L, Singh U. RNAi pathway genes are resistant to small RNA mediated gene silencing in the protozoan parasite Entamoeba histolytica. Plos One. 9: e106477. PMID 25198343 DOI: 10.1371/Journal.Pone.0106477 |
0.368 |
|
| 2014 |
Manna D, Ehrenkaufer GM, Singh U. Regulation of gene expression in the protozoan parasite Entamoeba invadens: identification of core promoter elements and promoters with stage-specific expression patterns. International Journal For Parasitology. 44: 837-45. PMID 25075445 DOI: 10.1016/J.Ijpara.2014.06.008 |
0.478 |
|
| 2014 |
Liu YC, Singh U. Destabilization domain approach adapted for regulated protein expression in the protozoan parasite Entamoeba histolytica. International Journal For Parasitology. 44: 729-35. PMID 24929134 DOI: 10.1016/J.Ijpara.2014.05.002 |
0.349 |
|
| 2013 |
Morf L, Pearson RJ, Wang AS, Singh U. Robust gene silencing mediated by antisense small RNAs in the pathogenic protist Entamoeba histolytica. Nucleic Acids Research. 41: 9424-37. PMID 23935116 DOI: 10.1093/Nar/Gkt717 |
0.457 |
|
| 2013 |
Ehrenkaufer GM, Weedall GD, Williams D, Lorenzi HA, Caler E, Hall N, Singh U. The genome and transcriptome of the enteric parasite Entamoeba invadens, a model for encystation. Genome Biology. 14: R77. PMID 23889909 DOI: 10.1186/Gb-2013-14-7-R77 |
0.382 |
|
| 2013 |
Zhang H, Ehrenkaufer GM, Hall N, Singh U. Small RNA pyrosequencing in the protozoan parasite Entamoeba histolytica reveals strain-specific small RNAs that target virulence genes. Bmc Genomics. 14: 53. PMID 23347563 DOI: 10.1186/1471-2164-14-53 |
0.363 |
|
| 2013 |
Pearson RJ, Morf L, Singh U. Regulation of H2O2 stress-responsive genes through a novel transcription factor in the protozoan pathogen Entamoeba histolytica. The Journal of Biological Chemistry. 288: 4462-74. PMID 23250742 DOI: 10.1074/Jbc.M112.423467 |
0.411 |
|
| 2012 |
Rastew E, Vicente JB, Singh U. Oxidative stress resistance genes contribute to the pathogenic potential of the anaerobic protozoan parasite, Entamoeba histolytica. International Journal For Parasitology. 42: 1007-15. PMID 23009748 DOI: 10.1016/J.Ijpara.2012.08.006 |
0.482 |
|
| 2012 |
Vicente JB, Tran V, Pinto L, Teixeira M, Singh U. A detoxifying oxygen reductase in the anaerobic protozoan Entamoeba histolytica. Eukaryotic Cell. 11: 1112-8. PMID 22798391 DOI: 10.1128/Ec.00149-12 |
0.36 |
|
| 2012 |
Morf L, Singh U. Entamoeba histolytica: a snapshot of current research and methods for genetic analysis. Current Opinion in Microbiology. 15: 469-75. PMID 22664276 DOI: 10.1016/J.Mib.2012.04.011 |
0.382 |
|
| 2012 |
Ehrenkaufer GM, Singh U. Transient and stable transfection in the protozoan parasite Entamoeba invadens. Molecular and Biochemical Parasitology. 184: 59-62. PMID 22561071 DOI: 10.1016/J.Molbiopara.2012.04.007 |
0.397 |
|
| 2011 |
Zhang H, Alramini H, Tran V, Singh U. Nucleus-localized antisense small RNAs with 5'-polyphosphate termini regulate long term transcriptional gene silencing in Entamoeba histolytica G3 strain. The Journal of Biological Chemistry. 286: 44467-79. PMID 22049083 DOI: 10.1074/Jbc.M111.278184 |
0.467 |
|
| 2011 |
Zhang H, Pompey JM, Singh U. RNA interference in Entamoeba histolytica: implications for parasite biology and gene silencing. Future Microbiology. 6: 103-17. PMID 21162639 DOI: 10.2217/Fmb.10.154 |
0.429 |
|
| 2010 |
Pearson RJ, Singh U. Approaches to characterizing Entamoeba histolytica transcriptional regulation. Cellular Microbiology. 12: 1681-90. PMID 20812994 DOI: 10.1111/J.1462-5822.2010.01524.X |
0.437 |
|
| 2010 |
Baxt LA, Rastew E, Bracha R, Mirelman D, Singh U. Downregulation of an Entamoeba histolytica rhomboid protease reveals roles in regulating parasite adhesion and phagocytosis. Eukaryotic Cell. 9: 1283-93. PMID 20581296 DOI: 10.1128/Ec.00015-10 |
0.756 |
|
| 2009 |
Ehrenkaufer GM, Hackney JA, Singh U. A developmentally regulated Myb domain protein regulates expression of a subset of stage-specific genes in Entamoeba histolytica. Cellular Microbiology. 11: 898-910. PMID 19239479 DOI: 10.1111/J.1462-5822.2009.01300.X |
0.451 |
|
| 2009 |
Linford AS, Moreno H, Good KR, Zhang H, Singh U, Petri WA. Short hairpin RNA-mediated knockdown of protein expression in Entamoeba histolytica. Bmc Microbiology. 9: 38. PMID 19222852 DOI: 10.1186/1471-2180-9-38 |
0.448 |
|
| 2009 |
Anderson MZ, Brewer J, Singh U, Boothroyd JC. A pseudouridine synthase homologue is critical to cellular differentiation in Toxoplasma gondii. Eukaryotic Cell. 8: 398-409. PMID 19124578 DOI: 10.1128/Ec.00329-08 |
0.393 |
|
| 2009 |
Singh U, Ehrenkaufer GM. Recent insights into Entamoeba development: identification of transcriptional networks associated with stage conversion. International Journal For Parasitology. 39: 41-7. PMID 18938171 DOI: 10.1016/J.Ijpara.2008.09.004 |
0.373 |
|
| 2009 |
Vicente JB, Ehrenkaufer GM, Saraiva LM, Teixeira M, Singh U. Entamoeba histolytica modulates a complex repertoire of novel genes in response to oxidative and nitrosative stresses: implications for amebic pathogenesis. Cellular Microbiology. 11: 51-69. PMID 18778413 DOI: 10.1111/J.1462-5822.2008.01236.X |
0.489 |
|
| 2008 |
Zhang H, Ehrenkaufer GM, Pompey JM, Hackney JA, Singh U. Small RNAs with 5'-polyphosphate termini associate with a Piwi-related protein and regulate gene expression in the single-celled eukaryote Entamoeba histolytica. Plos Pathogens. 4: e1000219. PMID 19043551 DOI: 10.1371/Journal.Ppat.1000219 |
0.44 |
|
| 2008 |
Ehrenkaufer GM, Singh U. Transcriptional regulatory networks in Entamoeba histolytica. Current Drug Targets. 9: 931-7. PMID 18991605 DOI: 10.2174/138945008786786109 |
0.518 |
|
| 2008 |
Baxt LA, Singh U. New insights into Entamoeba histolytica pathogenesis. Current Opinion in Infectious Diseases. 21: 489-94. PMID 18725798 DOI: 10.1097/Qco.0B013E32830Ce75F |
0.731 |
|
| 2008 |
Baxt LA, Baker RP, Singh U, Urban S. An Entamoeba histolytica rhomboid protease with atypical specificity cleaves a surface lectin involved in phagocytosis and immune evasion. Genes & Development. 22: 1636-46. PMID 18559479 DOI: 10.1101/Gad.1667708 |
0.751 |
|
| 2008 |
MacFarlane RC, Singh U. Loss of dsRNA-based gene silencing in Entamoeba histolytica: implications for approaches to genetic analysis. Experimental Parasitology. 119: 296-300. PMID 18346737 DOI: 10.1016/J.Exppara.2008.02.001 |
0.78 |
|
| 2007 |
Clark CG, Alsmark UC, Tazreiter M, Saito-Nakano Y, Ali V, Marion S, Weber C, Mukherjee C, Bruchhaus I, Tannich E, Leippe M, Sicheritz-Ponten T, Foster PG, Samuelson J, Noël CJ, ... ... Singh U, et al. Structure and content of the Entamoeba histolytica genome. Advances in Parasitology. 65: 51-190. PMID 18063096 DOI: 10.1016/S0065-308X(07)65002-7 |
0.388 |
|
| 2007 |
MacFarlane RC, Singh U. Identification of an Entamoeba histolytica serine-, threonine-, and isoleucine-rich protein with roles in adhesion and cytotoxicity. Eukaryotic Cell. 6: 2139-46. PMID 17827347 DOI: 10.1128/Ec.00174-07 |
0.784 |
|
| 2007 |
Ehrenkaufer GM, Eichinger DJ, Singh U. Trichostatin A effects on gene expression in the protozoan parasite Entamoeba histolytica. Bmc Genomics. 8: 216. PMID 17612405 DOI: 10.1186/1471-2164-8-216 |
0.433 |
|
| 2007 |
Davis CA, Brown MP, Singh U. Functional characterization of spliceosomal introns and identification of U2, U4, and U5 snRNAs in the deep-branching eukaryote Entamoeba histolytica. Eukaryotic Cell. 6: 940-8. PMID 17468393 DOI: 10.1128/Ec.00059-07 |
0.411 |
|
| 2007 |
Hackney JA, Ehrenkaufer GM, Singh U. Identification of putative transcriptional regulatory networks in Entamoeba histolytica using Bayesian inference. Nucleic Acids Research. 35: 2141-52. PMID 17355990 DOI: 10.1093/Nar/Gkm028 |
0.445 |
|
| 2007 |
Ehrenkaufer GM, Haque R, Hackney JA, Eichinger DJ, Singh U. Identification of developmentally regulated genes in Entamoeba histolytica: insights into mechanisms of stage conversion in a protozoan parasite. Cellular Microbiology. 9: 1426-44. PMID 17250591 DOI: 10.1111/J.1462-5822.2006.00882.X |
0.503 |
|
| 2007 |
Ali IK, Ehrenkaufer GM, Hackney JA, Singh U. Growth of the protozoan parasite Entamoeba histolytica in 5-azacytidine has limited effects on parasite gene expression. Bmc Genomics. 8: 7. PMID 17207281 DOI: 10.1186/1471-2164-8-7 |
0.443 |
|
| 2006 |
Gilchrist CA, Houpt E, Trapaidze N, Fei Z, Crasta O, Asgharpour A, Evans C, Martino-Catt S, Baba DJ, Stroup S, Hamano S, Ehrenkaufer G, Okada M, Singh U, Nozaki T, et al. Impact of intestinal colonization and invasion on the Entamoeba histolytica transcriptome. Molecular and Biochemical Parasitology. 147: 163-76. PMID 16569449 DOI: 10.1016/J.Molbiopara.2006.02.007 |
0.445 |
|
| 2006 |
MacFarlane RC, Singh U. Identification of differentially expressed genes in virulent and nonvirulent Entamoeba species: potential implications for amebic pathogenesis. Infection and Immunity. 74: 340-51. PMID 16368989 DOI: 10.1128/Iai.74.1.340-351.2006 |
0.787 |
|
| 2005 |
Vanchinathan P, Brewer JL, Harb OS, Boothroyd JC, Singh U. Disruption of a locus encoding a nucleolar zinc finger protein decreases tachyzoite-to-bradyzoite differentiation in Toxoplasma gondii. Infection and Immunity. 73: 6680-8. PMID 16177345 DOI: 10.1128/Iai.73.10.6680-6688.2005 |
0.45 |
|
| 2005 |
MacFarlane R, Bhattacharya D, Singh U. Genomic DNA microarrays for Entamoeba histolytica: applications for use in expression profiling and strain genotyping. Experimental Parasitology. 110: 196-202. PMID 15955312 DOI: 10.1016/J.Exppara.2005.03.006 |
0.777 |
|
| 2005 |
MacFarlane RC, Shah PH, Singh U. Transcriptional profiling of Entamoeba histolytica trophozoites. International Journal For Parasitology. 35: 533-42. PMID 15826645 DOI: 10.1016/J.Ijpara.2005.02.006 |
0.755 |
|
| 2005 |
Shah PH, MacFarlane RC, Bhattacharya D, Matese JC, Demeter J, Stroup SE, Singh U. Comparative genomic hybridizations of Entamoeba strains reveal unique genetic fingerprints that correlate with virulence. Eukaryotic Cell. 4: 504-15. PMID 15755913 DOI: 10.1128/Ec.4.3.504-515.2005 |
0.755 |
|
| 2005 |
Loftus B, Anderson I, Davies R, Alsmark UC, Samuelson J, Amedeo P, Roncaglia P, Berriman M, Hirt RP, Mann BJ, Nozaki T, Suh B, Pop M, Duchene M, Ackers J, ... ... Singh U, et al. The genome of the protist parasite Entamoeba histolytica. Nature. 433: 865-8. PMID 15729342 DOI: 10.1038/Nature03291 |
0.44 |
|
| 2004 |
Singh U, Shah PH, MacFarlane RC. DNA content analysis on microarrays. Methods in Molecular Biology (Clifton, N.J.). 270: 237-48. PMID 15153631 DOI: 10.1385/1-59259-793-9:237 |
0.764 |
|
| 2003 |
Boothroyd JC, Blader I, Cleary M, Singh U. DNA microarrays in parasitology: strengths and limitations. Trends in Parasitology. 19: 470-6. PMID 14519585 DOI: 10.1016/J.Pt.2003.08.002 |
0.347 |
|
| 2002 |
Cleary MD, Singh U, Blader IJ, Brewer JL, Boothroyd JC. Toxoplasma gondii asexual development: identification of developmentally regulated genes and distinct patterns of gene expression. Eukaryotic Cell. 1: 329-40. PMID 12455982 DOI: 10.1128/Ec.1.3.329-340.2002 |
0.486 |
|
| 2002 |
Matrajt M, Donald RG, Singh U, Roos DS. Identification and characterization of differentiation mutants in the protozoan parasite Toxoplasma gondii. Molecular Microbiology. 44: 735-47. PMID 11994154 DOI: 10.1046/J.1365-2958.2002.02904.X |
0.429 |
|
| 2002 |
Singh U, Brewer JL, Boothroyd JC. Genetic analysis of tachyzoite to bradyzoite differentiation mutants in Toxoplasma gondii reveals a hierarchy of gene induction. Molecular Microbiology. 44: 721-33. PMID 11994153 DOI: 10.1046/J.1365-2958.2002.02903.X |
0.427 |
|
| 2002 |
Singh U, Gilchrist CA, Schaenman JM, Rogers JB, Hockensmith JW, Mann BJ, Petri WA. Context-dependent roles of the Entamoeba histolytica core promoter element GAAC in transcriptional activation and protein complex assembly. Molecular and Biochemical Parasitology. 120: 107-16. PMID 11849710 DOI: 10.1016/S0166-6851(01)00441-8 |
0.326 |
|
| 2002 |
Singh U, Shah P. Investigating amoebic pathogenesis usingEntamoeba histolytica DNA microarrays Journal of Biosciences. 27: 595-601. DOI: 10.1007/Bf02704853 |
0.44 |
|
| 1999 |
Petri WA, Singh U. Diagnosis and management of amebiasis. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 29: 1117-25. PMID 10524950 DOI: 10.1086/313493 |
0.314 |
|
| 1998 |
Singh U, Rogers JB. The novel core promoter element GAAC in the hgl5 gene of Entamoeba histolytica is able to direct a transcription start site independent of TATA or initiator regions. The Journal of Biological Chemistry. 273: 21663-8. PMID 9705300 DOI: 10.1074/Jbc.273.34.21663 |
0.328 |
|
| 1997 |
Singh U, Rogers JB, Mann BJ, Petri WA. Transcription initiation is controlled by three core promoter elements in the hgl5 gene of the protozoan parasite Entamoeba histolytica. Proceedings of the National Academy of Sciences of the United States of America. 94: 8812-7. PMID 9238060 DOI: 10.1073/Pnas.94.16.8812 |
0.314 |
|
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