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Arno L. Greenleaf - Publications

Affiliations: 
Duke University, Durham, NC 
Area:
Biochemistry
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72 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Magnuson B, Bedi K, Narayanan IV, Bartkowiak B, Blinkiewicz H, Paulsen MT, Greenleaf A, Ljungman M. CDK12 regulates co-transcriptional splicing and RNA turnover in human cells. Iscience. 25: 105030. PMID 36111258 DOI: 10.1016/j.isci.2022.105030  0.435
2019 Bartkowiak B, Yan CM, Soderblom EJ, Greenleaf AL. CDK12 Activity-Dependent Phosphorylation Events in Human Cells. Biomolecules. 9. PMID 31652541 DOI: 10.3390/biom9100634  0.316
2019 Krajewska M, Dries R, Grassetti AV, Dust S, Gao Y, Huang H, Sharma B, Day DS, Kwiatkowski N, Pomaville M, Dodd O, Chipumuro E, Zhang T, Greenleaf AL, Yuan GC, et al. CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylation. Nature Communications. 10: 1757. PMID 30988284 DOI: 10.1038/S41467-019-09703-Y  0.499
2016 Zhang T, Kwiatkowski N, Olson CM, Dixon-Clarke SE, Abraham BJ, Greifenberg AK, Ficarro SB, Elkins JM, Liang Y, Hannett NM, Manz T, Hao M, Bartkowiak B, Greenleaf AL, Marto JA, et al. Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors. Nature Chemical Biology. PMID 27571479 DOI: 10.1038/Nchembio.2166  0.444
2015 Bartkowiak B, Yan C, Greenleaf AL. Engineering an analog-sensitive CDK12 cell line using CRISPR/Cas. Biochimica Et Biophysica Acta. 1849: 1179-87. PMID 26189575 DOI: 10.1016/J.Bbagrm.2015.07.010  0.429
2015 Bartkowiak B, Greenleaf AL. Expression, purification, and identification of associated proteins of the full-length hCDK12/CyclinK complex. The Journal of Biological Chemistry. 290: 1786-95. PMID 25429106 DOI: 10.1074/Jbc.M114.612226  0.557
2013 Winsor TS, Bartkowiak B, Bennett CB, Greenleaf AL. A DNA damage response system associated with the phosphoCTD of elongating RNA polymerase II. Plos One. 8: e60909. PMID 23613755 DOI: 10.1371/Journal.Pone.0060909  0.744
2013 Liu J, Fan S, Lee CJ, Greenleaf AL, Zhou P. Specific interaction of the transcription elongation regulator TCERG1 with RNA polymerase II requires simultaneous phosphorylation at Ser2, Ser5, and Ser7 within the carboxyl-terminal domain repeat. The Journal of Biological Chemistry. 288: 10890-901. PMID 23436654 DOI: 10.1074/Jbc.M113.460238  0.542
2012 Möller A, Xie SQ, Hosp F, Lang B, Phatnani HP, James S, Ramirez F, Collin GB, Naggert JK, Babu MM, Greenleaf AL, Selbach M, Pombo A. Proteomic analysis of mitotic RNA polymerase II reveals novel interactors and association with proteins dysfunctional in disease. Molecular & Cellular Proteomics : McP. 11: M111.011767. PMID 22199231 DOI: 10.1074/Mcp.M111.011767  0.752
2011 Bartkowiak B, Mackellar AL, Greenleaf AL. Updating the CTD Story: From Tail to Epic. Genetics Research International. 2011: 623718. PMID 22567360 DOI: 10.4061/2011/623718  0.779
2011 MacKellar AL, Greenleaf AL. Cotranscriptional association of mRNA export factor Yra1 with C-terminal domain of RNA polymerase II. The Journal of Biological Chemistry. 286: 36385-95. PMID 21856751 DOI: 10.1074/Jbc.M111.268144  0.797
2011 Bartkowiak B, Greenleaf AL. Phosphorylation of RNAPII: To P-TEFb or not to P-TEFb? Transcription. 2: 115-119. PMID 21826281 DOI: 10.4161/trns.2.3.15004  0.38
2011 Werner-Allen JW, Lee CJ, Liu P, Nicely NI, Wang S, Greenleaf AL, Zhou P. cis-Proline-mediated Ser(P)5 dephosphorylation by the RNA polymerase II C-terminal domain phosphatase Ssu72. The Journal of Biological Chemistry. 286: 5717-26. PMID 21159777 DOI: 10.1074/Jbc.M110.197129  0.488
2010 Bartkowiak B, Liu P, Phatnani HP, Fuda NJ, Cooper JJ, Price DH, Adelman K, Lis JT, Greenleaf AL. CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1. Genes & Development. 24: 2303-16. PMID 20952539 DOI: 10.1101/Gad.1968210  0.733
2010 Kanagaraj R, Huehn D, MacKellar A, Menigatti M, Zheng L, Urban V, Shevelev I, Greenleaf AL, Janscak P. RECQ5 helicase associates with the C-terminal repeat domain of RNA polymerase II during productive elongation phase of transcription. Nucleic Acids Research. 38: 8131-40. PMID 20705653 DOI: 10.1093/Nar/Gkq697  0.793
2010 Liu P, Kenney JM, Stiller JW, Greenleaf AL. Genetic organization, length conservation, and evolution of RNA polymerase II carboxyl-terminal domain. Molecular Biology and Evolution. 27: 2628-41. PMID 20558594 DOI: 10.1093/Molbev/Msq151  0.441
2010 Wu J, Phatnani HP, Hsieh TS, Greenleaf AL. The phosphoCTD-interacting domain of Topoisomerase I. Biochemical and Biophysical Research Communications. 397: 117-9. PMID 20493173 DOI: 10.1016/J.Bbrc.2010.05.081  0.733
2009 Westmoreland TJ, Wickramasekara SM, Guo AY, Selim AL, Winsor TS, Greenleaf AL, Blackwell KL, Olson JA, Marks JR, Bennett CB. Comparative genome-wide screening identifies a conserved doxorubicin repair network that is diploid specific in Saccharomyces cerevisiae. Plos One. 4: e5830. PMID 19503795 DOI: 10.1371/Journal.Pone.0005830  0.719
2008 Liu P, Greenleaf AL, Stiller JW. The essential sequence elements required for RNAP II carboxyl-terminal domain function in yeast and their evolutionary conservation. Molecular Biology and Evolution. 25: 719-27. PMID 18209193 DOI: 10.1093/Molbev/Msn017  0.496
2008 Bennett CB, Westmoreland TJ, Verrier CS, Blanchette CA, Sabin TL, Phatnani HP, Mishina YV, Huper G, Selim AL, Madison ER, Bailey DD, Falae AI, Galli A, Olson JA, Greenleaf AL, et al. Yeast screens identify the RNA polymerase II CTD and SPT5 as relevant targets of BRCA1 interaction. Plos One. 3: e1448. PMID 18197258 DOI: 10.1371/Journal.Pone.0001448  0.724
2006 Phatnani HP, Greenleaf AL. Phosphorylation and functions of the RNA polymerase II CTD. Genes & Development. 20: 2922-36. PMID 17079683 DOI: 10.1101/Gad.1477006  0.788
2006 Li M, Phatnani HP, Greenleaf AL, Zhou P. NMR assignment of the SRI domain of human Set2/HYPB. Journal of Biomolecular Nmr. 36: 5. PMID 16435090 DOI: 10.1007/S10858-005-4690-8  0.657
2005 Li M, Phatnani HP, Guan Z, Sage H, Greenleaf AL, Zhou P. Solution structure of the Set2-Rpb1 interacting domain of human Set2 and its interaction with the hyperphosphorylated C-terminal domain of Rpb1. Proceedings of the National Academy of Sciences of the United States of America. 102: 17636-41. PMID 16314571 DOI: 10.1073/Pnas.0506350102  0.742
2005 Kizer KO, Phatnani HP, Shibata Y, Hall H, Greenleaf AL, Strahl BD. A novel domain in Set2 mediates RNA polymerase II interaction and couples histone H3 K36 methylation with transcript elongation. Molecular and Cellular Biology. 25: 3305-16. PMID 15798214 DOI: 10.1128/Mcb.25.8.3305-3316.2005  0.73
2004 Phatnani HP, Jones JC, Greenleaf AL. Expanding the functional repertoire of CTD kinase I and RNA polymerase II: novel phosphoCTD-associating proteins in the yeast proteome. Biochemistry. 43: 15702-19. PMID 15595826 DOI: 10.1021/Bi048364H  0.787
2004 Jones JC, Phatnani HP, Haystead TA, MacDonald JA, Alam SM, Greenleaf AL. C-terminal repeat domain kinase I phosphorylates Ser2 and Ser5 of RNA polymerase II C-terminal domain repeats. The Journal of Biological Chemistry. 279: 24957-64. PMID 15047695 DOI: 10.1074/Jbc.M402218200  0.728
2004 Phatnani HP, Greenleaf AL. Identifying phosphoCTD-associating proteins. Methods in Molecular Biology (Clifton, N.J.). 257: 17-28. PMID 14769993 DOI: 10.1385/1-59259-750-5:017  0.771
2003 Greenleaf A. Getting a grip on the CTD of pol II Structure. 11: 900-902. PMID 12906819 DOI: 10.1016/S0969-2126(03)00164-3  0.495
2002 Skaar DA, Greenleaf AL. The RNA polymerase II CTD kinase CTDK-I affects pre-mRNA 3' cleavage/polyadenylation through the processing component Pti1p. Molecular Cell. 10: 1429-39. PMID 12504017 DOI: 10.1016/S1097-2765(02)00731-1  0.781
2002 Carty SM, Greenleaf AL. Hyperphosphorylated C-terminal repeat domain-associating proteins in the nuclear proteome link transcription to DNA/chromatin modification and RNA processing. Molecular & Cellular Proteomics : McP. 1: 598-610. PMID 12376575 DOI: 10.1074/Mcp.M200029-Mcp200  0.571
2001 Goldstrohm AC, Greenleaf AL, Garcia-Blanco MA. Co-transcriptional splicing of pre-messenger RNAs: considerations for the mechanism of alternative splicing. Gene. 277: 31-47. PMID 11602343 DOI: 10.1016/S0378-1119(01)00695-3  0.419
2001 Chao SH, Greenleaf AL, Price DH. Juglone, an inhibitor of the peptidyl-prolyl isomerase Pin1, also directly blocks transcription Nucleic Acids Research. 29: 767-773. PMID 11160900 DOI: 10.1093/Nar/29.3.767  0.554
2000 Morris DP, Greenleaf AL. The splicing factor, Prp40, binds the phosphorylated carboxyl-terminal domain of RNA Polymerase II Journal of Biological Chemistry. 275: 39935-39943. PMID 10978320 DOI: 10.1074/Jbc.M004118200  0.55
2000 Carty SM, Goldstrohm AC, Suñé C, Garcia-Blanco MA, Greenleaf AL. Protein-interaction modules that organize nuclear function: FF domains of CA150 bind the phosphoCTD of RNA polymerase II. Proceedings of the National Academy of Sciences of the United States of America. 97: 9015-20. PMID 10908677 DOI: 10.1073/Pnas.160266597  0.503
2000 Rodriguez CR, Cho EJ, Keogh MC, Moore CL, Greenleaf AL, Buratowski S. Kin28, the TFIIH-associated carboxy-terminal domain kinase, facilitates the recruitment of mRNA processing machinery to RNA polymerase II. Molecular and Cellular Biology. 20: 104-12. PMID 10594013 DOI: 10.1128/Mcb.20.1.104-112.2000  0.525
1999 Morris DP, Phatnani HP, Greenleaf AL. Phospho-carboxyl-terminal domain binding and the role of a prolyl isomerase in pre-mRNA 3'-End formation. The Journal of Biological Chemistry. 274: 31583-7. PMID 10531363 DOI: 10.1074/Jbc.274.44.31583  0.778
1998 Egyházi E, Ossoinak A, Lee JM, Greenleaf AL, Mäkelä TP, Pigon A. Heat-shock-specific phosphorylation and transcriptional activity of RNA polymerase II Experimental Cell Research. 242: 211-221. PMID 9665818 DOI: 10.1006/Excr.1998.4112  0.404
1998 Morris DP, Stevens RD, Greenleaf AL. Protonation of the neutral repeats of the RNA polymerase II CTD. Biochemical and Biophysical Research Communications. 245: 53-8. PMID 9535782 DOI: 10.1006/Bbrc.1998.8373  0.463
1997 Morris DP, Lee JM, Sterner DE, Brickey WJ, Greenleaf AL. Assaying CTD kinases in vitro and phosphorylation-modulated properties of RNA polymerase II in vivo. Methods (San Diego, Calif.). 12: 264-75. PMID 9237170 DOI: 10.1006/Meth.1997.0478  0.522
1997 Lee JM, Greenleaf AL. Modulation of RNA polymerase II elongation efficiency by C-terminal heptapeptide repeat domain kinase I Journal of Biological Chemistry. 272: 10990-10993. PMID 9110987 DOI: 10.1074/Jbc.272.17.10990  0.537
1996 Li B, Weber JA, Chen Y, Greenleaf AL, Gilmour DS. Analyses of promoter-proximal pausing by RNA polymerase II on the hsp70 heat shock gene promoter in a Drosophila nuclear extract Molecular and Cellular Biology. 16: 5433-5443. PMID 8816456 DOI: 10.1128/Mcb.16.10.5433  0.452
1996 Chen Y, Chafin D, Price DH, Greenleaf AL. Drosophila RNA polymerase II mutants that affect transcription elongation Journal of Biological Chemistry. 271: 5993-5999. PMID 8626382 DOI: 10.1074/Jbc.271.11.5993  0.446
1996 Egyházi E, Ossoinak A, Pigon A, Holmgren C, Lee JM, Greenleaf AL. Phosphorylation dependence of the initiation of productive transcription of Balbiani ring 2 genes in living cells Chromosoma. 104: 422-433. PMID 8601337 DOI: 10.1007/Bf00352266  0.492
1995 Sterner DE, Jae Moon Lee, Hardin SE, Greenleaf AL. The yeast carboxyl-terminal repeat domain kinase CTDK-I is a divergent cyclin-cyclin-dependent kinase complex Molecular and Cellular Biology. 15: 5716-5724. PMID 7565723 DOI: 10.1128/MCB.15.10.5716  0.361
1994 O'Brien T, Hardin S, Greenleaf A, Lis JT. Phosphorylation of RNA polymerase II C-terminal domain and transcriptional elongation. Nature. 370: 75-7. PMID 8015613 DOI: 10.1038/370075A0  0.572
1993 Greenleaf AL. Positive patches and negative noodles: linking RNA processing to transcription? Trends in Biochemical Sciences. 18: 117-119. PMID 8493720 DOI: 10.1016/0968-0004(93)90016-G  0.463
1993 Chen Y, Weeks J, Mortin MA, Greenleaf AL. Mapping mutations in genes encoding the two large subunits of Drosophila RNA polymerase II defines domains essential for basic transcription functions and for proper expression of developmental genes. Molecular and Cellular Biology. 13: 4214-22. PMID 8321225 DOI: 10.1128/Mcb.13.7.4214  0.403
1993 Weeks JR, Hardin SE, Shen J, Jae Moon Lee, Greenleaf AL. Locus-specific variation in phosphorylation state of RNA polymerase II in vivo: Correlations with gene activity and transcript processing Genes and Development. 7: 2329-2344. PMID 8253380 DOI: 10.1101/Gad.7.12A.2329  0.443
1992 Greenleaf AL. 3 RNA Polymerase II Subunits, Transcription Factors, and Kinases: Investigations in Drosophila melanogaster and Saccharomyces cerevisiae Cold Spring Harbor Monograph Archive. 55-80. DOI: 10.1101/087969425.22A.55  0.561
1989 Price DH, Sluder AE, Greenleaf AL. Dynamic interaction between a Drosophila transcription factor and RNA polymerase II Molecular and Cellular Biology. 9: 1465-1475. PMID 2725511 DOI: 10.1128/Mcb.9.4.1465  0.505
1989 Lee JM, Greenleaf AL. A protein kinase that phosphorylates the C-terminal repeat domain of the largest subunit of RNA polymerase II Proceedings of the National Academy of Sciences of the United States of America. 86: 3624-3628. PMID 2657724 DOI: 10.1073/Pnas.86.10.3624  0.536
1989 Jokerst RS, Weeks JR, Zehring WA, Greenleaf AL. Analysis of the gene encoding the largest subunit of RNA polymerase II in Drosophila Mgg Molecular &Amp; General Genetics. 215: 266-275. PMID 2496296 DOI: 10.1007/Bf00339727  0.56
1988 Zehring WA, Lee JM, Weeks JR, Jokerst RS, Greenleaf AL. The C-terminal repeat domain of RNA polymerase II largest subunit is essential in vivo but is not required for accurate transcription initiation in vitro Proceedings of the National Academy of Sciences of the United States of America. 85: 3698-3702. PMID 3131761 DOI: 10.1073/Pnas.85.11.3698  0.561
1987 Sluder AE, Price DH, Greenleaf AL. An activity necessary for in vitro transcription is a DNase inhibitor Biochimie. 69: 1199-1205. PMID 3129025 DOI: 10.1016/0300-9084(87)90147-7  0.475
1986 Greenleaf AL, Kelly JL, Lehman IR. Yeast RPO41 gene product is required for transcription and maintenance of the mitochondrial genome. Proceedings of the National Academy of Sciences of the United States of America. 83: 3391-4. PMID 3517858 DOI: 10.1073/Pnas.83.10.3391  0.388
1985 Biggs J, Searles LL, Greenleaf AL. Structure of the eukaryotic transcription apparatus: Features of the gene for the largest subunit of Drosophila RNA polymerase II Cell. 42: 611-621. PMID 2992806 DOI: 10.1016/0092-8674(85)90118-7  0.494
1984 Ingles CJ, Himmelfarb HJ, Shales M, Greenleaf AL, Friesen JD. Identification, molecular cloning, and mutagenesis of Saccharomyces cerevisiae RNA polymerase genes Proceedings of the National Academy of Sciences of the United States of America. 81: 2157-2161. PMID 6326108 DOI: 10.1073/Pnas.81.7.2157  0.543
1983 Jaenike J, Grimaldi DA, Sluder AE, Greenleaf AL. agr-Amanitin Tolerance in Mycophagous Drosophila. Science (New York, N.Y.). 221: 165-7. PMID 17769215 DOI: 10.1126/Science.221.4606.165  0.388
1983 Ingles CJ, Biggs J, Wong JKC, Weeks JR, Greenleaf AL. Identification of a structural gene for a RNA polymerase II polypeptide in Drosophila melanogaster and mammalian species Proceedings of the National Academy of Sciences of the United States of America. 80: 3396-3400. PMID 6407013 DOI: 10.1073/Pnas.80.11.3396  0.528
1982 Searles LL, Jokers RS, Bingham PM, Voelker RA, Greenleaf AL. Molecular cloning of sequences from a drosophila RNA polymerase II locus by P element transposon tagging Cell. 31: 585-592. PMID 6297774 DOI: 10.1016/0092-8674(82)90314-2  0.386
1980 Greenleaf AL, Weeks JR, Voelker RA, Ohnishi S, Dickson B. Genetic and biochemical characterization of mutants at an RNA polymerase II locus in D. melanogaster. Cell. 21: 785-92. PMID 6777048 DOI: 10.1016/0092-8674(80)90441-9  0.421
1979 Greenleaf AL, Borsett LM, Jiamachello PF, Coulter DE. α-amanitin-resistant D. melanogaster with an altered RNA polymerase II Cell. 18: 613-622. PMID 117900 DOI: 10.1016/0092-8674(79)90116-8  0.447
1978 Greenleaf AL, Plagens U, Jamrich M, Bautz EKF. RNA Polymerase B (or II) in heat induced puffs of Drosophila polytene chromosomes Chromosoma. 65: 127-136. PMID 414900 DOI: 10.1007/Bf00329465  0.397
1977 Jamrich M, Greenleaf AL, Bautz EKF. Localization of RNA polymerase in polytene chromosomes of Drosophila melanogaster Proceedings of the National Academy of Sciences of the United States of America. 74: 2079-2083. PMID 405671 DOI: 10.1073/Pnas.74.5.2079  0.44
1976 Plagens U, Greenleaf AL, Bautz EKF. Distribution of RNA polymerase on Drosophila polytene chromosomes as studied by indirect immunofluorescence Chromosoma. 59: 157-165. PMID 827428 DOI: 10.1007/Bf00328484  0.377
1976 Greenleaf AL, Haars R, Bautz EKF. In vitro proteolysis of a large subunit of Drosophila melanogaster RNA polymerase B Febs Letters. 71: 205-208. PMID 826408 DOI: 10.1016/0014-5793(76)80932-5  0.461
1976 Greenleaf AL, Krämer A, Bautz EKF. DNA-dependent RNA Polymerases from Drosophila melanogaster Larvae Cold Spring Harbor Monograph Archive. 6: 793-801. DOI: 10.1101/087969115.6.793  0.496
1975 Greenleaf AL, Bautz EKF. RNA polymerase B from Drosophila melanogaster larvae. Purification and partial characterization European Journal of Biochemistry. 60: 169-179. PMID 812697 DOI: 10.1111/J.1432-1033.1975.Tb20989.X  0.431
1975 Linn T, Greenleaf AL, Losick R. RNA polymerase from sporulating Bacillus subtilis. Purification and properties of a modified form of the enzyme containing two sporulation polypeptides Journal of Biological Chemistry. 250: 9256-9261. PMID 811662  0.676
1973 Greenleaf AL, Linn TG, Losick R. Isolation of a new RNA polymerase-binding protein from sporulating Bacillus subtilis Proceedings of the National Academy of Sciences of the United States of America. 70: 490-494. PMID 4631355 DOI: 10.1073/Pnas.70.2.490  0.75
1973 Greenleaf AL, Losick R. Appearance of a ribonucleic acid polymerase binding protein in asporogenous mutants of Bacillus subtilis Journal of Bacteriology. 116: 290-294. PMID 4200841 DOI: 10.1128/Jb.116.1.290-294.1973  0.572
1973 Linn TG, Greenleaf AL, Shorenstein RG, Losick R. Loss of the sigma activity of RNA polymerase of Bacillus subtilis during sporulation Proceedings of the National Academy of Sciences of the United States of America. 70: 1865-1869. PMID 4198276 DOI: 10.1073/Pnas.70.6.1865  0.781
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