Pierre A. Coulombe - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Biochemistry

63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Fu K, Sun X, Xia X, Hobbs RP, Guo Y, Coulombe PA, Wan F. Sam68 is required for the growth and survival of nonmelanoma skin cancer. Cancer Medicine. PMID 31436046 DOI: 10.1002/cam4.2513  0.56
2019 Majumdar R, Steen K, Coulombe PA, Parent CA. Non-canonical processes that shape the cell migration landscape. Current Opinion in Cell Biology. 57: 123-134. PMID 30852463 DOI: 10.1016/j.ceb.2018.12.013  0.32
2018 Wang F, Chen S, Liu HB, Parent CA, Coulombe PA. Keratin 6 regulates collective keratinocyte migration by altering cell-cell and cell-matrix adhesion. The Journal of Cell Biology. PMID 30389720 DOI: 10.1083/jcb.201712130  0.32
2016 Hobbs RP, Jacob JT, Coulombe PA. Keratins Are Going Nuclear. Developmental Cell. 38: 227-33. PMID 27505414 DOI: 10.1016/j.devcel.2016.07.022  0.56
2016 Kerns ML, Hakim JM, Lu RG, Guo Y, Berroth A, Kaspar RL, Coulombe PA. Oxidative stress and dysfunctional NRF2 underlie pachyonychia congenita phenotypes. The Journal of Clinical Investigation. PMID 27183391 DOI: 10.1172/JCI84870  1
2016 Wang F, Zieman A, Coulombe PA. Skin Keratins. Methods in Enzymology. 568: 303-50. PMID 26795476 DOI: 10.1016/bs.mie.2015.09.032  0.32
2015 Hobbs RP, DePianto DJ, Jacob JT, Han MC, Chung BM, Batazzi AS, Poll BG, Guo Y, Han J, Ong S, Zheng W, Taube JM, ?iháková D, Wan F, Coulombe PA. Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes. Nature Genetics. PMID 26168014 DOI: 10.1038/ng.3355  1
2015 Chung BM, Arutyunov A, Ilagan E, Yao N, Wills-Karp M, Coulombe PA. Regulation of C-X-C chemokine gene expression by keratin 17 and hnRNP K in skin tumor keratinocytes. The Journal of Cell Biology. 208: 613-27. PMID 25713416 DOI: 10.1083/jcb.201408026  1
2014 Richardson RJ, Hammond NL, Coulombe PA, Saloranta C, Nousiainen HO, Salonen R, Berry A, Hanley N, Headon D, Karikoski R, Dixon MJ. Periderm prevents pathological epithelial adhesions during embryogenesis. The Journal of Clinical Investigation. 124: 3891-900. PMID 25133425 DOI: 10.1172/JCI71946  1
2014 Alvarado DM, Coulombe PA. Directed expression of a chimeric type II keratin partially rescues keratin 5-null mice. The Journal of Biological Chemistry. 289: 19435-47. PMID 24867950 DOI: 10.1074/jbc.M114.553867  1
2014 van Steensel MA, Coulombe PA, Kaspar RL, Milstone LM, McLean IW, Roop DR, Smith FJ, Sprecher E, Schwartz ME. Report of the 10th Annual International Pachyonychia Congenita Consortium Meeting. The Journal of Investigative Dermatology. 134: 588-91. PMID 24518109 DOI: 10.1038/jid.2013.392  1
2013 Lessard JC, Piña-Paz S, Rotty JD, Hickerson RP, Kaspar RL, Balmain A, Coulombe PA. Keratin 16 regulates innate immunity in response to epidermal barrier breach Proceedings of the National Academy of Sciences of the United States of America. 110: 19537-19542. PMID 24218583 DOI: 10.1073/pnas.1309576110  1
2013 Chung BM, Rotty JD, Coulombe PA. Networking galore: intermediate filaments and cell migration. Current Opinion in Cell Biology. 25: 600-12. PMID 23886476 DOI: 10.1016/j.ceb.2013.06.008  1
2013 Pan X, Hobbs RP, Coulombe PA. The expanding significance of keratin intermediate filaments in normal and diseased epithelia. Current Opinion in Cell Biology. 25: 47-56. PMID 23270662 DOI: 10.1016/j.ceb.2012.10.018  0.56
2013 Feng X, Zhang H, Margolick JB, Coulombe PA. Keratin intracellular concentration revisited: implications for keratin function in surface epithelia. The Journal of Investigative Dermatology. 133: 850-3. PMID 23190880 DOI: 10.1038/jid.2012.397  1
2012 Hobbs RP, Lessard JC, Coulombe PA. Keratin intermediate filament proteins - novel regulators of inflammation and immunity in skin. Journal of Cell Science. 125: 5257-8. PMID 23377656 DOI: 10.1242/jcs.122929  1
2012 Kim JS, Lee CH, Su BY, Coulombe PA. Mathematical modeling of the impact of actin and keratin filaments on keratinocyte cell spreading. Biophysical Journal. 103: 1828-38. PMID 23199911 DOI: 10.1016/j.bpj.2012.09.016  0.92
2012 Lee CH, Kim MS, Chung BM, Leahy DJ, Coulombe PA. Structural basis for heteromeric assembly and perinuclear organization of keratin filaments. Nature Structural & Molecular Biology. 19: 707-15. PMID 22705788 DOI: 10.1038/nsmb.2330  1
2012 Rotty JD, Coulombe PA. A wound-induced keratin inhibits Src activity during keratinocyte migration and tissue repair. The Journal of Cell Biology. 197: 381-9. PMID 22529101 DOI: 10.1083/jcb.201107078  1
2012 Lessard JC, Coulombe PA. Keratin 16-null mice develop palmoplantar keratoderma, a hallmark feature of pachyonychia congenita and related disorders. The Journal of Investigative Dermatology. 132: 1384-91. PMID 22336941 DOI: 10.1038/jid.2012.6  1
2012 Coulombe PA, Lee CH. Defining keratin protein function in skin epithelia: epidermolysis bullosa simplex and its aftermath. The Journal of Investigative Dermatology. 132: 763-75. PMID 22277943 DOI: 10.1038/jid.2011.450  0.92
2012 Chung BM, Murray CI, Van Eyk JE, Coulombe PA. Identification of novel interaction between annexin A2 and keratin 17: evidence for reciprocal regulation. The Journal of Biological Chemistry. 287: 7573-81. PMID 22235123 DOI: 10.1074/jbc.M111.301549  1
2011 Pan X, Kane LA, Van Eyk JE, Coulombe PA. Type I keratin 17 protein is phosphorylated on serine 44 by p90 ribosomal protein S6 kinase 1 (RSK1) in a growth- and stress-dependent fashion. The Journal of Biological Chemistry. 286: 42403-13. PMID 22006917 DOI: 10.1074/jbc.M111.302042  0.4
2010 Kim JS, Lee CH, Coulombe PA. Modeling the self-organization property of keratin intermediate filaments. Biophysical Journal. 99: 2748-56. PMID 21044571 DOI: 10.1016/j.bpj.2010.09.023  0.92
2010 Rotty JD, Hart GW, Coulombe PA. Stressing the role of O-GlcNAc: linking cell survival to keratin modification. Nature Cell Biology. 12: 847-9. PMID 20811358 DOI: 10.1038/ncb0910-847  1
2010 Kim S, Coulombe PA. Emerging role for the cytoskeleton as an organizer and regulator of translation. Nature Reviews. Molecular Cell Biology. 11: 75-81. PMID 20027187 DOI: 10.1038/nrm2818  0.48
2009 Lee CH, Coulombe PA. Self-organization of keratin intermediate filaments into cross-linked networks. The Journal of Cell Biology. 186: 409-21. PMID 19651890 DOI: 10.1083/jcb.200810196  0.92
2009 Coulombe PA, Kerns ML, Fuchs E. Epidermolysis bullosa simplex: a paradigm for disorders of tissue fragility. The Journal of Clinical Investigation. 119: 1784-93. PMID 19587453 DOI: 10.1172/JCI38177  1
2008 Huang SM, Lee H, Chung MK, Park U, Yu YY, Bradshaw HB, Coulombe PA, Walker JM, Caterina MJ. Overexpressed transient receptor potential vanilloid 3 ion channels in skin keratinocytes modulate pain sensitivity via prostaglandin E2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 13727-37. PMID 19091963 DOI: 10.1523/JNEUROSCI.5741-07.2008  1
2008 Larouche D, Tong X, Fradette J, Coulombe PA, Germain L. Vibrissa hair bulge houses two populations of skin epithelial stem cells distinct by their keratin profile. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 1404-15. PMID 18162489 DOI: 10.1096/fj.07-8109com  1
2007 Kim S, Kellner J, Lee CH, Coulombe PA. Interaction between the keratin cytoskeleton and eEF1Bgamma affects protein synthesis in epithelial cells. Nature Structural & Molecular Biology. 14: 982-3. PMID 17906640 DOI: 10.1038/nsmb1301  0.92
2007 Kerns ML, DePianto D, Dinkova-Kostova AT, Talalay P, Coulombe PA. Reprogramming of keratin biosynthesis by sulforaphane restores skin integrity in epidermolysis bullosa simplex Proceedings of the National Academy of Sciences of the United States of America. 104: 14460-14465. PMID 17724334 DOI: 10.1073/pnas.0706486104  1
2007 Kim S, Coulombe PA. Intermediate filament scaffolds fulfill mechanical, organizational, and signaling functions in the cytoplasm. Genes & Development. 21: 1581-97. PMID 17606637 DOI: 10.1101/gad.1552107  0.48
2007 Leung CT, Coulombe PA, Reed RR. Contribution of olfactory neural stem cells to tissue maintenance and regeneration. Nature Neuroscience. 10: 720-6. PMID 17468753 DOI: 10.1038/nn1882  1
2006 Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW. New consensus nomenclature for mammalian keratins. The Journal of Cell Biology. 174: 169-74. PMID 16831889 DOI: 10.1083/jcb.200603161  1
2006 Kim S, Wong P, Coulombe PA. A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth. Nature. 441: 362-5. PMID 16710422 DOI: 10.1038/nature04659  0.48
2006 Tong X, Coulombe PA. Keratin 17 modulates hair follicle cycling in a TNFalpha-dependent fashion. Genes & Development. 20: 1353-64. PMID 16702408 DOI: 10.1101/gad.1387406  1
2005 Beaudoin GM, Sisk JM, Coulombe PA, Thompson CC. Hairless triggers reactivation of hair growth by promoting Wnt signaling. Proceedings of the National Academy of Sciences of the United States of America. 102: 14653-8. PMID 16195376 DOI: 10.1073/pnas.0507609102  1
2005 Bianchi N, Depianto D, McGowan K, Gu C, Coulombe PA. Exploiting the keratin 17 gene promoter to visualize live cells in epithelial appendages of mice. Molecular and Cellular Biology. 25: 7249-59. PMID 16055733 DOI: 10.1128/MCB.25.16.7249-7259.2005  0.4
2005 Bernot KM, Lee CH, Coulombe PA. A small surface hydrophobic stripe in the coiled-coil domain of type I keratins mediates tetramer stability. The Journal of Cell Biology. 168: 965-74. PMID 15767464 DOI: 10.1083/jcb.200408116  0.92
2005 Wong P, Domergue R, Coulombe PA. Overcoming functional redundancy to elicit pachyonychia congenita-like nail lesions in transgenic mice. Molecular and Cellular Biology. 25: 197-205. PMID 15601842 DOI: 10.1128/MCB.25.1.197-205.2005  0.36
2004 Coulombe PA, Tong X, Mazzalupo S, Wang Z, Wong P. Great promises yet to be fulfilled: defining keratin intermediate filament function in vivo. European Journal of Cell Biology. 83: 735-46. PMID 15679118 DOI: 10.1078/0171-9335-00443  1
2004 Bernot KM, Coulombe PA, Wong P. Skin: an ideal model system to study keratin genes and proteins. Methods in Cell Biology. 78: 453-87. PMID 15646628  0.76
2004 Callahan CA, Ofstad T, Horng L, Wang JK, Zhen HH, Coulombe PA, Oro AE. MIM/BEG4, a Sonic hedgehog-responsive gene that potentiates Gli-dependent transcription Genes and Development. 18: 2724-2729. PMID 15545630 DOI: 10.1101/gad.1221804  1
2004 Presland RB, Coulombe PA, Eckert RL, Mao-Qiang M, Feingold KR, Elias PM. Barrier function in transgenic mice overexpressing K16, involucrin, and filaggrin in the suprabasal epidermis. The Journal of Investigative Dermatology. 123: 603-6. PMID 15304104 DOI: 10.1111/j.0022-202X.2004.23226.x  1
2004 Coulombe PA, Wong P. Cytoplasmic intermediate filaments revealed as dynamic and multipurpose scaffolds. Nature Cell Biology. 6: 699-706. PMID 15303099 DOI: 10.1038/ncb0804-699  0.36
2004 Zarach JM, Beaudoin GM, Coulombe PA, Thompson CC. The co-repressor hairless has a role in epithelial cell differentiation in the skin. Development (Cambridge, England). 131: 4189-200. PMID 15280217 DOI: 10.1242/dev.01303  1
2004 Tong X, Coulombe PA. A novel mouse type I intermediate filament gene, keratin 17n (K17n), exhibits preferred expression in nail tissue. The Journal of Investigative Dermatology. 122: 965-70. PMID 15102087 DOI: 10.1111/j.0022-202X.2004.22422.x  1
2003 Wang Z, Wong P, Langbein L, Schweizer J, Coulombe PA. Type II epithelial keratin 6hf (K6hf) is expressed in the companion layer, matrix, and medulla in anagen-stage hair follicles. The Journal of Investigative Dermatology. 121: 1276-82. PMID 14675170 DOI: 10.1111/j.1523-1747.2003.12644.x  1
2003 Wong P, Coulombe PA. Loss of keratin 6 (K6) proteins reveals a function for intermediate filaments during wound repair. The Journal of Cell Biology. 163: 327-37. PMID 14568992 DOI: 10.1083/jcb.200305032  0.36
2003 Yamada S, Wirtz D, Coulombe PA. The mechanical properties of simple epithelial keratins 8 and 18: discriminating between interfacial and bulk elasticities. Journal of Structural Biology. 143: 45-55. PMID 12892725 DOI: 10.1016/S1047-8477(03)00101-1  1
2003 Tong X, Coulombe PA. Mouse models of alopecia: identifying structural genes that are baldly needed. Trends in Molecular Medicine. 9: 79-84. PMID 12615042  1
2003 Mazzalupo S, Wong P, Martin P, Coulombe PA. Role for keratins 6 and 17 during wound closure in embryonic mouse skin. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 226: 356-65. PMID 12557214 DOI: 10.1002/dvdy.10245  0.56
2002 Bernot KM, Coulombe PA, McGowan KM. Keratin 16 expression defines a subset of epithelial cells during skin morphogenesis and the hair cycle. The Journal of Investigative Dermatology. 119: 1137-49. PMID 12445204 DOI: 10.1046/j.1523-1747.2002.19518.x  0.76
2002 McGowan KM, Tong X, Colucci-Guyon E, Langa F, Babinet C, Coulombe PA. Keratin 17 null mice exhibit age- and strain-dependent alopecia. Genes & Development. 16: 1412-22. PMID 12050118 DOI: 10.1101/gad.979502  1
2002 Mazzalupo S, Wawersik MJ, Coulombe PA. An ex vivo assay to assess the potential of skin keratinocytes for wound epithelialization. The Journal of Investigative Dermatology. 118: 866-70. PMID 11982766 DOI: 10.1046/j.1523-1747.2002.01736.x  0.56
2002 Yamada S, Wirtz D, Coulombe PA. Pairwise assembly determines the intrinsic potential for self-organization and mechanical properties of keratin filaments. Molecular Biology of the Cell. 13: 382-91. PMID 11809846 DOI: 10.1091/mbc.01-10-0522  1
2001 Coulombe PA, Ma L, Yamada S, Wawersik M. Intermediate filaments at a glance. Journal of Cell Science. 114: 4345-7. PMID 11792800  0.56
2001 Bousquet O, Ma L, Yamada S, Gu C, Idei T, Takahashi K, Wirtz D, Coulombe PA. The nonhelical tail domain of keratin 14 promotes filament bundling and enhances the mechanical properties of keratin intermediate filaments in vitro. The Journal of Cell Biology. 155: 747-54. PMID 11724817 DOI: 10.1083/jcb.200104063  0.56
2001 Wawersik MJ, Mazzalupo S, Nguyen D, Coulombe PA. Increased levels of keratin 16 alter epithelialization potential of mouse skin keratinocytes in vivo and ex vivo. Molecular Biology of the Cell. 12: 3439-50. PMID 11694579  0.56
2001 Ma L, Yamada S, Wirtz D, Coulombe PA. A 'hot-spot' mutation alters the mechanical properties of keratin filament networks. Nature Cell Biology. 3: 503-6. PMID 11331879 DOI: 10.1038/35074576  1
2000 Coulombe PA, Bousquet O, Ma L, Yamada S, Wirtz D. The 'ins' and 'outs' of intermediate filament organization. Trends in Cell Biology. 10: 420-8. PMID 10998598  0.56
1999 Ma L, Xu J, Coulombe PA, Wirtz D. Keratin filament suspensions show unique micromechanical properties. The Journal of Biological Chemistry. 274: 19145-51. PMID 10383419 DOI: 10.1074/jbc.274.27.19145  1
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