| Year |
Citation |
Score |
| 2023 |
Estelle AB, George A, Barbar EJ, Zuckerman DM. Quantifying cooperative multisite binding in the hub protein LC8 through Bayesian inference. Plos Computational Biology. 19: e1011059. PMID 37083599 DOI: 10.1371/journal.pcbi.1011059 |
0.439 |
|
| 2023 |
Walker DR, Jara KA, Rolland AD, Brooks C, Hare W, Swansiger AK, Reardon PN, Prell JS, Barbar EJ. Linker Length Drives Heterogeneity of Multivalent Complexes of Hub Protein LC8 and Transcription Factor ASCIZ. Biomolecules. 13. PMID 36979339 DOI: 10.3390/biom13030404 |
0.451 |
|
| 2023 |
Jara KA, Barbar EJ. NMR Analysis of the Interactions and Conformational Plasticity of Dynein Intermediate Chain. Methods in Molecular Biology (Clifton, N.J.). 2623: 241-256. PMID 36602690 DOI: 10.1007/978-1-0716-2958-1_15 |
0.396 |
|
| 2022 |
Jara KA, Loening NM, Reardon PN, Yu Z, Woonnimani P, Brooks C, Vesely CH, Barbar EJ. Multivalency, autoinhibition, and protein disorder in the regulation of interactions of dynein intermediate chain with dynactin and the nuclear distribution protein. Elife. 11. PMID 36416224 DOI: 10.7554/eLife.80217 |
0.507 |
|
| 2022 |
Howe J, Weeks A, Reardon P, Barbar E. Multivalent binding of the hub protein LC8 at a newly discovered site in 53BP1. Biophysical Journal. 121: 4433-4442. PMID 36335430 DOI: 10.1016/j.bpj.2022.11.006 |
0.393 |
|
| 2021 |
Rodriguez Galvan J, Donner B, Veseley CH, Reardon P, Forsythe HM, Howe J, Fujimura G, Barbar E. Human Parainfluenza Virus 3 Phosphoprotein Is a Tetramer and Shares Structural and Interaction Features with Ebola Phosphoprotein VP35. Biomolecules. 11. PMID 34827601 DOI: 10.3390/biom11111603 |
0.318 |
|
| 2021 |
Forsythe HM, Barbar E. The role of dancing duplexes in biology and disease. Progress in Molecular Biology and Translational Science. 183: 249-270. PMID 34656330 DOI: 10.1016/bs.pmbts.2021.06.004 |
0.429 |
|
| 2021 |
Morgan JL, Yeager A, Estelle AB, Gsponer J, Barbar E. Transient Tertiary Structures of Disordered Dynein Intermediate Chain Regulate its Interactions with Multiple Partners. Journal of Molecular Biology. 433: 167152. PMID 34273400 DOI: 10.1016/j.jmb.2021.167152 |
0.48 |
|
| 2021 |
Forsythe HM, Galvan JR, Yu Z, Pinckney S, Reardon P, Cooley RB, Zhu P, Rolland AD, Prell JS, Barbar E. Multivalent binding of the partially disordered SARS-CoV-2 nucleocapsid phosphoprotein dimer to RNA. Biophysical Journal. PMID 33794152 DOI: 10.1016/j.bpj.2021.03.023 |
0.366 |
|
| 2021 |
Loening NM, Barbar E. Structural characterization of the self-association domain of swallow. Protein Science : a Publication of the Protein Society. PMID 33641207 DOI: 10.1002/pro.4055 |
0.388 |
|
| 2020 |
Loening NM, Saravanan S, Jespersen NE, Jara K, Barbar E. Interplay of Disorder and Sequence Specificity in the Formation of Stable Dynein-Dynactin Complexes. Biophysical Journal. 119: 950-965. PMID 32814057 DOI: 10.1016/J.Bpj.2020.07.023 |
0.523 |
|
| 2020 |
Jespersen N, Barbar E. Emerging Features of Linear Motif-Binding Hub Proteins: (Trends in Biochemical Sciences, 45, 375-3849, 2020). Trends in Biochemical Sciences. PMID 32601043 DOI: 10.1016/J.Tibs.2020.06.002 |
0.439 |
|
| 2020 |
Jespersen N, Barbar E. Emerging Features of Linear Motif-Binding Hub Proteins. Trends in Biochemical Sciences. 45: 375-384. PMID 32311332 DOI: 10.1016/J.Tibs.2020.01.004 |
0.539 |
|
| 2020 |
Reardon PN, Jara KA, Rolland AD, Smith DA, Hoang HTM, Prell JS, Barbar EJ. The dynein light chain 8 (LC8) binds "in-register" to multivalent intrinsically disordered partners. The Journal of Biological Chemistry. PMID 32139510 DOI: 10.1074/Jbc.Ra119.011653 |
0.502 |
|
| 2019 |
Jespersen NE, Leyrat C, Gérard FC, Bourhis JM, Blondel D, Jamin M, Barbar E. The LC8-RavP ensemble structure evinces a role for LC8 in regulating Lyssavirus polymerase functionality. Journal of Molecular Biology. PMID 31634467 DOI: 10.1016/J.Jmb.2019.10.011 |
0.462 |
|
| 2019 |
Jespersen N, Estelle A, Waugh N, Davey NE, Blikstad C, Ammon YC, Akhmanova A, Ivarsson Y, Hendrix DA, Barbar E. Systematic identification of recognition motifs for the hub protein LC8. Life Science Alliance. 2. PMID 31266884 DOI: 10.26508/lsa.201900366 |
0.394 |
|
| 2018 |
Clark SA, Myers JB, King A, Fiala R, Novacek J, Pearce FG, Heierhorst J, Reichow SL, Barbar EJ. Multivalency regulates activity in an intrinsically disordered transcription factor. Elife. 7. PMID 29714690 DOI: 10.7554/Elife.36258 |
0.326 |
|
| 2017 |
Morgan J, Jensen MR, Ozenne V, Blackledge M, Barbar EJ. The LC8 Recognition Motif Preferentially Samples Polyproline II Structure in its Free State. Biochemistry. PMID 28792212 DOI: 10.1021/Acs.Biochem.7B00552 |
0.604 |
|
| 2017 |
Jie J, Löhr F, Barbar E. Dynein Binding of Competitive Regulators Dynactin and NudE Involves Novel Interplay between Phosphorylation Site and Disordered Spliced Linkers. Structure (London, England : 1993). PMID 28162951 DOI: 10.1016/J.Str.2017.01.003 |
0.508 |
|
| 2016 |
Clark S, Nyarko A, Löhr F, Karplus PA, Barbar E. The Anchored Flexibility Model in LC8 Motif Recognition: Insights from the Chica Complex. Biochemistry. 55: 199-209. PMID 26652654 DOI: 10.1021/Acs.Biochem.5B01099 |
0.791 |
|
| 2016 |
Jie J, Barbar E. Regulation of Mammalian Dynein Intermediate Chain Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.1929 |
0.602 |
|
| 2015 |
Jie J, Löhr F, Barbar E. Interactions of Yeast Dynein with Dynein Light Chain and Dynactin: GENERAL IMPLICATIONS FOR INTRINSICALLY DISORDERED DUPLEX SCAFFOLDS IN MULTIPROTEIN ASSEMBLIES. The Journal of Biological Chemistry. 290: 23863-74. PMID 26253171 DOI: 10.1074/Jbc.M115.649715 |
0.611 |
|
| 2015 |
Clark SA, Jespersen N, Woodward C, Barbar E. Multivalent IDP assemblies: Unique properties of LC8-associated, IDP duplex scaffolds. Febs Letters. 589: 2543-51. PMID 26226419 DOI: 10.1016/J.Febslet.2015.07.032 |
0.58 |
|
| 2015 |
Baßler J, Paternoga H, Holdermann I, Thoms M, Granneman S, Barrio-Garcia C, Nyarko A, Lee W, Stier G, Clark SA, Schraivogel D, Kallas M, Beckmann R, Tollervey D, Barbar E, et al. A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation. The Journal of Cell Biology. 210: 169-70. PMID 26150393 DOI: 10.1083/jcb.20140811106112015c |
0.67 |
|
| 2015 |
Lampi KJ, Murray MR, Peterson MP, Eng BS, Yue E, Clark AR, Barbar E, David LL. Differences in solution dynamics between lens β-crystallin homodimers and heterodimers probed by hydrogen-deuterium exchange and deamidation. Biochimica Et Biophysica Acta. PMID 26145577 DOI: 10.1016/J.Bbagen.2015.06.014 |
0.375 |
|
| 2015 |
Gaik M, Flemming D, von Appen A, Kastritis P, Mücke N, Fischer J, Stelter P, Ori A, Bui KH, Baßler J, Barbar E, Beck M, Hurt E. Structural basis for assembly and function of the Nup82 complex in the nuclear pore scaffold. The Journal of Cell Biology. 208: 283-97. PMID 25646085 DOI: 10.1083/Jcb.201411003 |
0.38 |
|
| 2015 |
Barbar E, Nyarko A. Polybivalency and disordered proteins in ordering macromolecular assemblies. Seminars in Cell & Developmental Biology. 37: 20-5. PMID 25263009 DOI: 10.1016/J.Semcdb.2014.09.016 |
0.794 |
|
| 2015 |
Jie J, Barbar E. Protein Disorder in Dynein Regulation by Dynactin and NudE Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.2124 |
0.596 |
|
| 2014 |
Bassler J, Paternoga H, Holdermann I, Thoms M, Granneman S, Barrio-Garcia C, Nyarko A, Stier G, Clark SA, Schraivogel D, Kallas M, Beckmann R, Tollervey D, Barbar E, Sinning I, et al. A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation. The Journal of Cell Biology. 207: 481-98. PMID 25404745 DOI: 10.1083/Jcb.201408111 |
0.741 |
|
| 2014 |
Nyarko A, Singarapu KK, Figueroa M, Manning VA, Pandelova I, Wolpert TJ, Ciuffetti LM, Barbar E. Solution NMR structures of Pyrenophora tritici-repentis ToxB and its inactive homolog reveal potential determinants of toxin activity. The Journal of Biological Chemistry. 289: 25946-56. PMID 25063993 DOI: 10.1074/Jbc.M114.569103 |
0.729 |
|
| 2014 |
Barbar E, Nyarko A. NMR Characterization of Self-Association Domains Promoted by Interactions with LC8 Hub Protein. Computational and Structural Biotechnology Journal. 9: e201402003. PMID 24757501 DOI: 10.5936/Csbj.201402003 |
0.797 |
|
| 2014 |
Jie J, Barbar E. Structural Basis of Multiple Sequential LC8 Sites: Insights from Interactions of Lc8 with Pac11 Biophysical Journal. 106: 6-8. DOI: 10.1016/J.Bpj.2013.11.3807 |
0.622 |
|
| 2014 |
Nyarko A, Song Y, Barbar E. Multiple Recognition Motifs Provide Rigidity to Stabilize LC8 Complexes Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.3795 |
0.788 |
|
| 2013 |
Kidane AI, Song Y, Nyarko A, Hall J, Hare M, Löhr F, Barbar E. Structural features of LC8-induced self-association of swallow. Biochemistry. 52: 6011-20. PMID 23914803 DOI: 10.1021/Bi400642U |
0.781 |
|
| 2013 |
Nyarko A, Song Y, Nováček J, Žídek L, Barbar E. Multiple recognition motifs in nucleoporin Nup159 provide a stable and rigid Nup159-Dyn2 assembly. The Journal of Biological Chemistry. 288: 2614-22. PMID 23223634 DOI: 10.1074/Jbc.M112.432831 |
0.806 |
|
| 2013 |
Barbar E. Intrinsic Protein Disorder in the Regulation of Large Molecular Machines Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.052 |
0.508 |
|
| 2012 |
Barbar E. Native disorder mediates binding of dynein to NudE and dynactin. Biochemical Society Transactions. 40: 1009-13. PMID 22988856 DOI: 10.1042/Bst20120180 |
0.481 |
|
| 2012 |
Nyarko A, Song Y, Barbar E. Intrinsic disorder in dynein intermediate chain modulates its interactions with NudE and dynactin. The Journal of Biological Chemistry. 287: 24884-93. PMID 22669947 DOI: 10.1074/Jbc.M112.376038 |
0.802 |
|
| 2012 |
Powell JD, Barbar E, Dreher TW. Turnip yellow mosaic virus forms infectious particles without the native beta-annulus structure and flexible coat protein N-terminus Virology. 422: 165-173. PMID 22078163 DOI: 10.1016/J.Virol.2011.10.019 |
0.312 |
|
| 2011 |
Morgan JL, Song Y, Barbar E. Structural dynamics and multiregion interactions in dynein-dynactin recognition. The Journal of Biological Chemistry. 286: 39349-59. PMID 21931160 DOI: 10.1074/Jbc.M111.296277 |
0.587 |
|
| 2011 |
Nyarko A, Hall J, Hall A, Hare M, Kremerskothen J, Barbar E. Conformational dynamics promote binding diversity of dynein light chain LC8. Biophysical Chemistry. 159: 41-7. PMID 21621319 DOI: 10.1016/J.Bpc.2011.05.001 |
0.784 |
|
| 2011 |
Nyarko A, Barbar E. Light chain-dependent self-association of dynein intermediate chain. The Journal of Biological Chemistry. 286: 1556-66. PMID 20974845 DOI: 10.1074/Jbc.M110.171686 |
0.794 |
|
| 2010 |
Hall J, Song Y, Karplus PA, Barbar E. The crystal structure of dynein intermediate chain-light chain roadblock complex gives new insights into dynein assembly. The Journal of Biological Chemistry. 285: 22566-75. PMID 20472935 DOI: 10.1074/Jbc.M110.103861 |
0.546 |
|
| 2010 |
Nyarko A, Barbar E. Light Chain-Mediated Self-Association of Intrinsically Disordered Dynein Intermediate Chain Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.3578 |
0.807 |
|
| 2009 |
Benison G, Chiodo M, Karplus PA, Barbar E. Structural, thermodynamic, and kinetic effects of a phosphomimetic mutation in dynein light chain LC8. Biochemistry. 48: 11381-9. PMID 19863079 DOI: 10.1021/Bi901589W |
0.494 |
|
| 2009 |
Hall J, Karplus PA, Barbar E. Multivalency in the assembly of intrinsically disordered Dynein intermediate chain. The Journal of Biological Chemistry. 284: 33115-21. PMID 19759397 DOI: 10.1074/Jbc.M109.048587 |
0.549 |
|
| 2009 |
Hall A, Parsonage D, Horita D, Karplus PA, Poole LB, Barbar E. Redox-dependent dynamics of a dual thioredoxin fold protein: evolution of specialized folds. Biochemistry. 48: 5984-93. PMID 19459661 DOI: 10.1021/Bi900270W |
0.362 |
|
| 2009 |
Benison G, Barbar E. NMR analysis of dynein light chain dimerization and interactions with diverse ligands. Methods in Enzymology. 455: 237-58. PMID 19289209 DOI: 10.1016/S0076-6879(08)04209-2 |
0.559 |
|
| 2009 |
Barbar E, Hall J, Benison G, Karplus PA, Nyarko A. Mechanisms Underlying the Binding Diversity of Dynein Light Chain Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.2876 |
0.818 |
|
| 2008 |
Benison G, Karplus PA, Barbar E. The interplay of ligand binding and quaternary structure in the diverse interactions of dynein light chain LC8. Journal of Molecular Biology. 384: 954-66. PMID 18948118 DOI: 10.1016/J.Jmb.2008.09.083 |
0.545 |
|
| 2008 |
Hall J, Hall A, Pursifull N, Barbar E. Differences in dynamic structure of LC8 monomer, dimer, and dimer-peptide complexes. Biochemistry. 47: 11940-52. PMID 18942858 DOI: 10.1021/Bi801093K |
0.539 |
|
| 2008 |
Barbar E. Dynein light chain LC8 is a dimerization hub essential in diverse protein networks. Biochemistry. 47: 503-8. PMID 18092820 DOI: 10.1021/Bi701995M |
0.444 |
|
| 2007 |
Benison G, Karplus PA, Barbar E. Structure and dynamics of LC8 complexes with KXTQT-motif peptides: swallow and dynein intermediate chain compete for a common site. Journal of Molecular Biology. 371: 457-68. PMID 17570393 DOI: 10.1016/J.Jmb.2007.05.046 |
0.601 |
|
| 2007 |
Song Y, Benison G, Nyarko A, Hays TS, Barbar E. Potential role for phosphorylation in differential regulation of the assembly of dynein light chains. The Journal of Biological Chemistry. 282: 17272-9. PMID 17428790 DOI: 10.1074/Jbc.M610445200 |
0.791 |
|
| 2006 |
Benison G, Nyarko A, Barbar E. Heteronuclear NMR identifies a nascent helix in intrinsically disordered dynein intermediate chain: implications for folding and dimerization. Journal of Molecular Biology. 362: 1082-93. PMID 16949604 DOI: 10.1016/J.Jmb.2006.08.006 |
0.8 |
|
| 2006 |
Talbott M, Hare M, Nyarko A, Hays TS, Barbar E. Folding is coupled to dimerization of Tctex-1 dynein light chain. Biochemistry. 45: 6793-800. PMID 16734416 DOI: 10.1021/Bi0600345 |
0.72 |
|
| 2005 |
Nyarko A, Cochrun L, Norwood S, Pursifull N, Voth A, Barbar E. Ionization of His 55 at the dimer interface of dynein light-chain LC8 is coupled to dimer dissociation Biochemistry. 44: 14248-14255. PMID 16245941 DOI: 10.1021/Bi0512694 |
0.744 |
|
| 2004 |
Nyarko A, Hare M, Hays TS, Barbar E. The intermediate chain of cytoplasmic dynein is partially disordered and gains structure upon binding to light-chain LC8. Biochemistry. 43: 15595-603. PMID 15581372 DOI: 10.1021/Bi048451+ |
0.807 |
|
| 2004 |
Wang L, Hare M, Hays TS, Barbar E. Dynein light chain LC8 promotes assembly of the coiled-coil domain of swallow protein. Biochemistry. 43: 4611-20. PMID 15078108 DOI: 10.1021/Bi036328X |
0.498 |
|
| 2004 |
Barbar E, Hare M. Characterization of the cargo attachment complex of cytoplasmic dynein using NMR and mass spectrometry. Methods in Enzymology. 380: 219-41. PMID 15051340 DOI: 10.1016/S0076-6879(04)80011-9 |
0.316 |
|
| 2004 |
Makokha M, Huang YJ, Montelione G, Edison AS, Barbar E. The solution structure of the pH-induced monomer of dynein light-chain LC8 from Drosophila Protein Science. 13: 727-734. PMID 14767079 DOI: 10.1110/Ps.03462204 |
0.418 |
|
| 2003 |
Nyarko A, Hare M, Makokha M, Barbar E. Interactions of LC8 with N-terminal segments of the intermediate chain of cytoplasmic dynein. Thescientificworldjournal. 3: 647-54. PMID 12920307 DOI: 10.1100/Tsw.2003.56 |
0.796 |
|
| 2002 |
Barbar E, Makokha M, Hare M. Protein Interactions Within the Cytoplasmic Dynein Complex as Probed by Mass Spectrometry and Nmr. Thescientificworldjournal. 2: 95-96. PMID 29973819 DOI: 10.1100/Tsw.2002.45 |
0.6 |
|
| 2002 |
Makokha M, Hare M, Li M, Hays T, Barbar E. Interactions of cytoplasmic dynein light chains Tctex-1 and LC8 with the intermediate chain IC74. Biochemistry. 41: 4302-11. PMID 11914076 DOI: 10.1021/Bi011970H |
0.527 |
|
| 2001 |
Barbar E, Hare M, Makokha M, Barany G, Woodward C. NMR-detected order in core residues of denatured bovine pancreatic trypsin inhibitor. Biochemistry. 40: 9734-42. PMID 11583174 DOI: 10.1021/Bi010483Z |
0.385 |
|
| 2001 |
Woodward C, Barbar E, Carulla N, Battiste J, Barany G. Experimental approaches to protein folding based on the concept of a slow hydrogen exchange core. Journal of Molecular Graphics & Modelling. 19: 94-101. PMID 11381535 DOI: 10.1016/S1093-3263(00)00131-5 |
0.383 |
|
| 2001 |
Barbar E, Kleinman B, Imhoff D, Li M, Hays TS, Hare M. Dimerization and folding of LC8, a highly conserved light chain of cytoplasmic dynein Biochemistry. 40: 1596-1605. PMID 11327818 DOI: 10.1021/Bi002278+ |
0.458 |
|
| 1999 |
Barbar E. NMR characterization of partially folded and unfolded conformational ensembles of proteins. Biopolymers. 51: 191-207. PMID 10516571 DOI: 10.1002/(Sici)1097-0282(1999)51:3<191::Aid-Bip3>3.0.Co;2-B |
0.439 |
|
| 1998 |
Barbar E, Hare M, Daragan V, Barany G, Woodward C. Dynamics of the conformational ensemble of partially folded bovine pancreatic trypsin inhibitor. Biochemistry. 37: 7822-33. PMID 9601043 DOI: 10.1021/Bi973102J |
0.387 |
|
| 1997 |
Barbar E, Gross CM, Woodward C, Barany G. Chemical synthesis and nuclear magnetic resonance characterization of partially folded proteins. Methods in Enzymology. 289: 587-611. PMID 9353740 DOI: 10.1016/S0076-6879(97)89066-0 |
0.351 |
|
| 1997 |
Barbar E, LiCata VJ, Barany G, Woodward C. Local fluctuations and global unfolding of partially folded BPTI detected by NMR. Biophysical Chemistry. 64: 45-57. PMID 9127937 DOI: 10.1016/S0301-4622(96)02210-7 |
0.375 |
|
| 1996 |
Barbar E, Barany G, Woodward C. Unfolded BPTI variants with a single disulfide bond have diminished non-native structure distant from the crosslink. Folding & Design. 1: 65-76. PMID 9079365 DOI: 10.1016/S1359-0278(96)00013-2 |
0.39 |
|
| 1996 |
Barbar E, Martin TM, Brown M, Rittenberg MB, Peyton DH. Binding of phenylphosphocholine-carrier conjugates to the combining site of antibodies maintains a conformation of the hapten Biochemistry. 35: 2958-2967. PMID 8608133 DOI: 10.1021/Bi950823E |
0.453 |
|
| 1996 |
Barany G, Gross CM, Ferrer M, Barbar E, Pan H, Woodward C. Optimized methods for chemical synthesis of bovine pancreatic trypsin inhibitor (BPTI) analogues Techniques in Protein Chemistry. 7: 503-514. DOI: 10.1016/S1080-8914(96)80055-X |
0.347 |
|
| 1995 |
Breslow E, Sardana V, Deeb R, Barbar E, Peyton DH. NMR behavior of the aromatic protons of bovine neurophysin-I and its peptide complexes: Implications for solution structure and for function Biochemistry. 34: 2137-2147. PMID 7857924 DOI: 10.1021/Bi00007A006 |
0.489 |
|
| 1995 |
Pan H, Barbar E, Barany G, Woodward C. Extensive nonrandom structure in reduced and unfolded bovine pancreatic trypsin inhibitor. Biochemistry. 34: 13974-81. PMID 7577994 DOI: 10.1021/Bi00043A002 |
0.423 |
|
| 1995 |
Barbar E, Barany G, Woodward C. Dynamic structure of a highly ordered beta-sheet molten globule: multiple conformations with a stable core. Biochemistry. 34: 11423-434. PMID 7547870 DOI: 10.1021/Bi00036A015 |
0.388 |
|
| 1992 |
Bruderer U, Peyton DH, Barbar E, Fellman JH, Rittenberg MB. Hapten conformation in the combining site of antibodies that bind phenylphosphocholine. Biochemistry. 31: 584-9. PMID 1731913 DOI: 10.1021/Bi00117A040 |
0.409 |
|
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