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Karol S. Bruzik - Publications

Affiliations: 
University of Illinois at Chicago, Health Sciences Center, Chicago, IL 60612, United States 
Area:
Biochemistry
Website:
https://pharmacy.uic.edu/people-resources/directory/kbruzik

128 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Jayakar SS, Chiara DC, Zhou X, Wu B, Bruzik KS, Miller KW, Cohen JB. Photoaffinity labeling identifies an intersubunit steroid-binding site in heteromeric GABA type A (GABA) receptors. The Journal of Biological Chemistry. PMID 32540960 DOI: 10.1074/Jbc.Ra120.013452  1
2020 Shalabi AR, Yu Z, Zhou X, Jounaidi Y, Chen H, Dai J, Kent DE, Feng HJ, Forman SA, Cohen JB, Bruzik KS, Miller KW. A potent photoreactive general anesthetic with novel binding site selectivity for GABA receptors. European Journal of Medicinal Chemistry. 194: 112261. PMID 32247113 DOI: 10.1016/J.Ejmech.2020.112261  1
2019 Kent DE, Savechenkov PY, Bruzik KS, Miller KW. Binding Site Location on GABA Rs Determines Whether Mixtures of Intravenous General Anesthetics Interact Synergistically or Additively in vivo. British Journal of Pharmacology. PMID 31454409 DOI: 10.1111/Bph.14843  1
2019 Jayakar SS, Zhou X, Chiara DC, Jarava-Barrera C, Savechenkov PY, Bruzik KS, Tortosa M, Miller KW, Cohen JB. Identifying drugs that bind selectively to intersubunit general anesthetic sites in the α1β3γ2 GABAR transmembrane domain. Molecular Pharmacology. PMID 30952799 DOI: 10.1124/Mol.118.114975  1
2019 Yu Z, Chiara DC, Savechenkov PY, Bruzik KS, Cohen JB. A photoreactive analog of allopregnanolone enables identification of steroid-binding sites in a nicotinic acetylcholine receptor. The Journal of Biological Chemistry. PMID 30923128 DOI: 10.1074/Jbc.Ra118.007172  1
2019 Yu Z, Savechenkov PY, Bruzik KS, Cohen JB. Identifying Steroid Binding Sites in a Nicotinic Acetylcholine Receptor (nAChR) with a Photoreactive Analog of Alphaxalone Biophysical Journal. 116: 395a. DOI: 10.1016/J.Bpj.2018.11.2135  0.01
2019 Chiara DC, Wu B, Zhou X, Jayakar SS, Titterton K, Forman SA, Miller KW, Bruzik KS, Cohen JB. Identification of a High-Affinity Neurosteroid Binding Site in Human Alpha1Beta3 GabaAR using a Photoreactive Thdoc Analog Biophysical Journal. 116: 392a. DOI: 10.1016/J.Bpj.2018.11.2123  0.01
2019 Jayakar SS, Zhou X, Wu B, Miller KW, Bruzik KS, Cohen JB. Pharmacological Selectivity of a Steroid Binding Site at the Beta+-Alpha− Interface of Alpha1 Beta3 Gaba-A Receptors Biophysical Journal. 116: 392a. DOI: 10.1016/J.Bpj.2018.11.2122  0.01
2018 Wu B, Jayakar SS, Zhou X, Titterton K, Chiara DC, Szabo AL, Savechenkov PY, Kent DE, Cohen JB, Forman SA, Miller KW, Bruzik KS. Inhibitable photolabeling by neurosteroid diazirine analog in the β3-Subunit of human hetereopentameric type A GABA receptors. European Journal of Medicinal Chemistry. 162: 810-824. PMID 30544077 DOI: 10.1016/J.Ejmech.2018.11.019  1
2017 Savechenkov PY, Chiara DC, Desai R, Stern AT, Zhou X, Ziemba AM, Szabo AL, Zhang Y, Cohen JB, Forman SA, Miller KW, Bruzik KS. Synthesis and pharmacological evaluation of neurosteroid photoaffinity ligands. European Journal of Medicinal Chemistry. 136: 334-347. PMID 28505538 DOI: 10.1016/J.Ejmech.2017.04.043  1
2016 Chiara DC, Jounaidi Y, Zhou X, Savechenkov PY, Bruzik KS, Miller KW, Cohen JB. General Anesthetic Binding Sites in Human α4β3δ γ-Aminobutyric Acid Type-A Receptors (GABAAR). The Journal of Biological Chemistry. PMID 27821594 DOI: 10.1074/Jbc.M116.753335  1
2016 Chiara DC, Savechenkov PY, Zhou X, Desai R, Stern AT, Zhang Y, Forman SA, Bruzik KS, Miller KW, Cohen JB. Interactions of a Photoreactive Steroid Anesthetic (F4N3-Alphaxalone) with Human α1β3γ2 GABA-A Receptors Biophysical Journal. 110: 455a. DOI: 10.1016/J.Bpj.2015.11.2438  0.01
2016 Jayakar SS, Zhou X, Savechenkov PY, Bruzik KS, Miller KW, Cohen JB. Identifying GABA-A Receptor Modulators that Bind to Intersubunit Sites in the GABA-A Receptor Transmembrane Domain Biophysical Journal. 110: 454a-455a. DOI: 10.1016/J.Bpj.2015.11.2437  0.01
2015 Jiao C, Summerlin M, Bruzik KS, Hanakahi L. Synthesis of Biotinylated Inositol Hexakisphosphate To Study DNA Double-Strand Break Repair and Affinity Capture of IP6-Binding Proteins. Biochemistry. 54: 6312-22. PMID 26397942 DOI: 10.1021/Acs.Biochem.5B00642  1
2015 Desai R, Savechenkov PY, Zolkowska D, Ge RL, Rogawski MA, Bruzik KS, Forman SA, Raines DE, Miller KW. Contrasting actions of a convulsant barbiturate and its anti-convulsant enantiomer on the α1β3γ2L GABAA receptor account for their in vivo effects. The Journal of Physiology. PMID 26378885 DOI: 10.1113/Jp270971  1
2015 Jayakar SS, Zhou X, Savechenkov PY, Chiara DC, Desai R, Bruzik KS, Miller KW, Cohen JB. Positive and Negative Allosteric Modulation of an α1β3γ2 γ-Aminobutyric acid Type A (GABAA) Receptor by Binding to a Site in the Transmembrane Domain at the γ+-β- Interface. The Journal of Biological Chemistry. PMID 26229099 DOI: 10.1074/Jbc.M115.672006  1
2014 Jayakar SS, Zhou X, Chiara DC, Dostalova Z, Savechenkov PY, Bruzik KS, Dailey WP, Miller KW, Eckenhoff RG, Cohen JB. Multiple propofol-binding sites in a γ-aminobutyric acid type A receptor (GABAAR) identified using a photoreactive propofol analog. The Journal of Biological Chemistry. 289: 27456-68. PMID 25086038 DOI: 10.1074/Jbc.M114.581728  1
2014 Hamouda AK, Stewart DS, Chiara DC, Savechenkov PY, Bruzik KS, Cohen JB. Identifying barbiturate binding sites in a nicotinic acetylcholine receptor with [3H]allyl m-trifluoromethyldiazirine mephobarbital, a photoreactive barbiturate. Molecular Pharmacology. 85: 735-46. PMID 24563544 DOI: 10.1124/Mol.113.090985  1
2013 Chiara DC, Jayakar SS, Zhou X, Zhang X, Savechenkov PY, Bruzik KS, Miller KW, Cohen JB. Specificity of intersubunit general anesthetic-binding sites in the transmembrane domain of the human α1β3γ2 γ-aminobutyric acid type A (GABAA) receptor. The Journal of Biological Chemistry. 288: 19343-57. PMID 23677991 DOI: 10.1074/Jbc.M113.479725  1
2012 Shanmugasundararaj S, Das J, Sandberg WS, Zhou X, Wang D, Messing RO, Bruzik KS, Stehle T, Miller KW. Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase Cδ*. Biophysical Journal. 103: 2331-40. PMID 23283232 DOI: 10.1016/J.Bpj.2012.10.034  1
2012 Yue L, Pawlowski M, Dellal SS, Xie A, Feng F, Otis TS, Bruzik KS, Qian H, Pepperberg DR. Robust photoregulation of GABA(A) receptors by allosteric modulation with a propofol analogue. Nature Communications. 3: 1095. PMID 23033071 DOI: 10.1038/Ncomms2094  1
2012 Savechenkov PY, Zhang X, Chiara DC, Stewart DS, Ge R, Zhou X, Raines DE, Cohen JB, Forman SA, Miller KW, Bruzik KS. Allyl m-trifluoromethyldiazirine mephobarbital: an unusually potent enantioselective and photoreactive barbiturate general anesthetic. Journal of Medicinal Chemistry. 55: 6554-65. PMID 22734650 DOI: 10.1021/Jm300631E  1
2012 Corda D, Zizza P, Varone A, Bruzik KS, Mariggiò S. The glycerophosphoinositols and their cellular functions. Biochemical Society Transactions. 40: 101-7. PMID 22260673 DOI: 10.1042/Bst20110679  0.01
2011 Stewart DS, Savechenkov PY, Dostalova Z, Chiara DC, Ge R, Raines DE, Cohen JB, Forman SA, Bruzik KS, Miller KW. p-(4-Azipentyl)propofol: a potent photoreactive general anesthetic derivative of propofol. Journal of Medicinal Chemistry. 54: 8124-35. PMID 22029276 DOI: 10.1021/Jm200943F  1
2011 Yue L, Xie A, Bruzik KS, Frølund B, Qian H, Pepperberg DR. Potentiating action of propofol at GABAA receptors of retinal bipolar cells. Investigative Ophthalmology & Visual Science. 52: 2497-509. PMID 21071744 DOI: 10.1167/Iovs.10-5991  1
2011 Kruszynski R, Czubacka E, Trzesowska-Kruszynska A, Bartczak TJ, Bruzik KS, Knopik P, Kudzin Z, Stec WJ, Wolf WM. Conformation of Sterically Hindered 4-Methyl-2-oxo-2-trityl-1,3,2-dioxaphosphorinane in the Solid State and the Solution Journal of Chemical Crystallography. 41: 908-918. DOI: 10.1007/S10870-011-0102-Y  0.01
2010 Bai C, Zhao L, Tsai MD, Bruzik KS. Unique catalytic mechanism of phosphatidylinositol-specific phospholipase C from Streptomyces antibioticus. Journal of the American Chemical Society. 132: 1210-1. PMID 20052980 DOI: 10.1021/Ja908285H  1
2010 Mihai C, Yue X, Zhao L, Kravchuk A, Tsai MD, Bruzik KS. Nonhydrolyzable analogs of phosphatidylinositol as ligands of phospholipases C New Journal of Chemistry. 34: 925-933. DOI: 10.1039/B9Nj00629J  1
2010 SOLOMONS KRH, FREEMAN S, SCHWALBE CH, SHEARS SB, NELSON DJ, XIE W, BRUZIK KS, KAETZEL MA. ChemInform Abstract: Synthesis of D-1,2-Dideoxy-1,2-difluoro-myo-inositol 3,4,5,6-Tetrakisphosphate (I) and Its Enantiomer as Analogues of myo-Inositol 3,4,5,6-Tetrakisphosphate. Cheminform. 29: no-no. DOI: 10.1002/chin.199849260  0.01
2010 MIHAI C, MATAKA J, RIDDLE S, TSAI M, BRUZIK KS. ChemInform Abstract: Synthesis of Enantiomerically Pure Phosphorothiolate Assay Substrate for Phosphatidylinositol-Specific Phospholipase C. Cheminform. 28: no-no. DOI: 10.1002/chin.199739247  0.01
2010 KUBIAK RJ, BRUZIK KS. ChemInform Abstract: Synthesis of Phosphorothioate Analogues of Phosphatidylinositol 3,4,5- Trisphosphate. Cheminform. 28: no-no. DOI: 10.1002/chin.199739246  0.01
2010 BRUZIK KS, GUAN Z, RIDDLE S, TSAI M. ChemInform Abstract: Synthesis of Inositol Phosphodiesters by Phospholipase C-Catalyzed Transesterification. Cheminform. 27: no-no. DOI: 10.1002/chin.199648238  0.01
2010 BRUZIK KS, KUBIAK RJ. ChemInform Abstract: General Synthesis of Phosphatidylinositol 3-Phosphates. Cheminform. 26: no-no. DOI: 10.1002/chin.199531245  0.01
2010 BRUZIK KS, TSAI M. ChemInform Abstract: Efficient and Systematic Syntheses of Enantiomerically Pure and Regiospecifically Protected myo-Inositols. Cheminform. 23: no-no. DOI: 10.1002/chin.199247241  0.01
2010 PIETRUSIEWICZ KM, SALAMONCZYK GM, BRUZIK KS, WIECZOREK W. ChemInform Abstract: The Synthesis of Homochiral Inositol Phosphates from myo-Inositol. Cheminform. 23: no-no. DOI: 10.1002/chin.199242239  0.01
2010 BRUZIK KS, MYERS J, TSAI M. ChemInform Abstract: Practical Synthesis of Enantiomerically Pure myo-Inositol Derivatives. Cheminform. 23: no-no. DOI: 10.1002/chin.199237290  0.01
2010 BRUZIK KS, LIN G, TSAI M. ChemInform Abstract: Phosphorothioate Analogues of Phosphatidylinositol and Inositol 1,2- Cyclic Phosphate. Application to the Mechanism of Phospholipase C Cheminform. 23: no-no. DOI: 10.1002/chin.199201338  0.01
2010 KNOPIK P, BRUZIK KS, STEC WJ. ChemInform Abstract: An Improved Synthesis of 6-(O-Phosphorylcholine)hydroxyhexanoic Acid. Cheminform. 22: no-no. DOI: 10.1002/chin.199145226  0.01
2010 BRUZIK KS, STEC WJ. ChemInform Abstract: Reversible Oxidation of Phosphylthionates (I) and Phosphylselenonates ( III) with Trifluoroacetic Anhydride. Cheminform. 22: no-no. DOI: 10.1002/chin.199118081  0.01
2010 SALAMONCZYK GM, BRUZIK KS. ChemInform Abstract: The Synthesis of Diastereomers of Phosphorothioate Analogue of Dipalmitoylphosphatidylinositol (VI). Cheminform. 22: no-no. DOI: 10.1002/chin.199105306  0.01
2009 Bai C, Zhao L, Rebecchi M, Tsai MD, Bruzik KS. Trans-cyclization of phosphatidylinositol catalyzed by phospholipase C from Streptomyces antibioticus. Journal of the American Chemical Society. 131: 8362-3. PMID 19492832 DOI: 10.1021/Ja902326U  1
2007 Liu Y, Mihai C, Kubiak RJ, Rebecchi M, Bruzik KS. Phosphorothiolate analogues of phosphatidylinositols as assay substrates for phospholipase C. Chembiochem : a European Journal of Chemical Biology. 8: 1430-9. PMID 17659518 DOI: 10.1002/Cbic.200700061  1
2006 Stahelin RV, Karathanassis D, Bruzik KS, Waterfield MD, Bravo J, Williams RL, Cho W. Structural and membrane binding analysis of the Phox homology domain of phosphoinositide 3-kinase-C2alpha. The Journal of Biological Chemistry. 281: 39396-406. PMID 17038310 DOI: 10.1074/Jbc.M607079200  1
2004 Stahelin RV, Ananthanarayanan B, Blatner NR, Singh S, Bruzik KS, Murray D, Cho W. Mechanism of membrane binding of the phospholipase D1 PX domain. The Journal of Biological Chemistry. 279: 54918-26. PMID 15475361 DOI: 10.1074/Jbc.M407798200  1
2003 Liu Y, Bruzik KS, Ananthanarayanan B, Cho W. New aspects of formation of 1,2-cyclic phosphates by phospholipase C-delta1. Bioorganic & Medicinal Chemistry. 11: 2471-5. PMID 12735994 DOI: 10.1016/S0968-0896(03)00150-0  1
2003 Mihai C, Kravchuk AV, Tsai MD, Bruzik KS. Application of Brønsted-type LFER in the study of the phospholipase C mechanism. Journal of the American Chemical Society. 125: 3236-42. PMID 12630878 DOI: 10.1021/Ja029362S  1
2003 Kravchuk AV, Zhao L, Bruzik KS, Tsai MD. Engineering a catalytic metal binding site into a calcium-independent phosphatidylinositol-specific phospholipase C leads to enhanced stereoselectivity. Biochemistry. 42: 2422-30. PMID 12600209 DOI: 10.1021/Bi0271953  1
2003 Kubiak RJ, Bruzik KS. Comprehensive and uniform synthesis of all naturally occurring phosphorylated phosphatidylinositols. The Journal of Organic Chemistry. 68: 960-8. PMID 12558421 DOI: 10.1021/Jo0206418  1
2003 Stahelin RV, Burian A, Bruzik KS, Murray D, Cho W. Membrane binding mechanisms of the PX domains of NADPH oxidase p40phox and p47phox. The Journal of Biological Chemistry. 278: 14469-79. PMID 12556460 DOI: 10.1074/Jbc.M212579200  1
2003 Zhao L, Liu Y, Bruzik KS, Tsai MD. A novel calcium-dependent bacterial phosphatidylinositol-specific phospholipase C displaying unprecedented magnitudes of thio effect, inverse thio effect, and stereoselectivity. Journal of the American Chemical Society. 125: 22-3. PMID 12515492 DOI: 10.1021/Ja029019N  1
2002 Stahelin RV, Long F, Diraviyam K, Bruzik KS, Murray D, Cho W. Phosphatidylinositol 3-phosphate induces the membrane penetration of the FYVE domains of Vps27p and Hrs. The Journal of Biological Chemistry. 277: 26379-88. PMID 12006563 DOI: 10.1074/Jbc.M201106200  1
2001 Kubiak RJ, Bruzik KS. Reactivities of inositol and ribonucleoside phosphodiesters toward P--O bond cleavage. Journal of the American Chemical Society. 123: 1760-1. PMID 11456778 DOI: 10.1021/Ja003675A  0.01
2001 Kravchuk AV, Zhao L, Kubiak RJ, Bruzik KS, Tsai MD. Mechanism of phosphatidylinositol-specific phospholipase C: origin of unusually high nonbridging thio effects. Biochemistry. 40: 5433-9. PMID 11331007 DOI: 10.1021/Bi002372Q  1
2001 Kubiak RJ, Yue X, Hondal RJ, Mihai C, Tsai MD, Bruzik KS. Involvement of the Arg-Asp-His catalytic triad in enzymatic cleavage of the phosphodiester bond. Biochemistry. 40: 5422-32. PMID 11331006 DOI: 10.1021/Bi002371Y  1
2001 Bruzik KS. Molecular and Supramolecular Chemistry of Natural Products and Their Model Compounds By Jürgen-Hinrich Fuhrhop (Free University of Berlin) and Claus Endisch (Berlin, Germany). Marcel Dekker:  New York. 2000. x + 602 pp. $195.00. ISBN 0-8247-8201-1 Journal of the American Chemical Society. 123: 1016-1016. DOI: 10.1021/Ja0047119  0.01
2000 Hengge AC, Bruzik KS, Tobin AE, Cleland WW, Tsai MD. Kinetic Isotope Effects and Stereochemical Studies on a Ribonuclease Model: Hydrolysis Reactions of Uridine 3'-Nitrophenyl Phosphate. Bioorganic Chemistry. 28: 119-133. PMID 10915550 DOI: 10.1006/Bioo.2000.1170  1
1999 Yang X, Rudolf M, Carew MA, Yoshida M, Nerreter V, Riley AM, Chung SK, Bruzik KS, Potter BV, Schultz C, Shears SB. Inositol 1,3,4-trisphosphate acts in vivo as a specific regulator of cellular signaling by inositol 3,4,5,6-tetrakisphosphate. The Journal of Biological Chemistry. 274: 18973-80. PMID 10383396 DOI: 10.1074/Jbc.274.27.18973  1
1999 Kubiak RJ, Hondal RJ, Yue X, Tsai MD, Bruzik KS. Identification of a novel catalytic triad with dual functions in enzymatic cleavage of the P-O bond Journal of the American Chemical Society. 121: 488-489. DOI: 10.1021/Ja9834677  1
1999 Hondal RJ, Zhao Z, Kravchuk AV, Liao H, Riddle SR, Bruzik KS, Tsai MD. Mechanism of phosphatidylinositol-specific phospholipase C revealed by protein engineering and phosphorothioate analogs of phosphatidylinositol Acs Symposium Series. 718: 109-120.  1
1998 Xie W, Solomons KR, Freeman S, Kaetzel MA, Bruzik KS, Nelson DJ, Shears SB. Regulation of Ca2+-dependent Cl- conductance in a human colonic epithelial cell line (T84): cross-talk between Ins(3,4,5,6)P4 and protein phosphatases. The Journal of Physiology. 661-73. PMID 9660883 DOI: 10.1111/J.1469-7793.1998.661Bj.X  0.01
1998 Hondal RJ, Zhao Z, Kravchuk AV, Liao H, Riddle SR, Yue X, Bruzik KS, Tsai MD. Mechanism of phosphatidylinositol-specific phospholipase C: A unified view of the mechanism of catalysis Biochemistry. 37: 4568-4580. PMID 9521777 DOI: 10.1021/Bi972646I  1
1998 Nilius B, Prenen J, Voets T, Eggermont J, Bruzik KS, Shears SB, Droogmans G. Inhibition by inositoltetrakisphosphates of calcium- and volume-activated Cl- currents in macrovascular endothelial cells. Pflugers Archiv : European Journal of Physiology. 435: 637-44. PMID 9479016 DOI: 10.1007/S004240050564  0.01
1998 Solomons KR, Freeman S, Schwalbe CH, Shears SB, Nelson DJ, Xie W, Bruzik KS, Kaetzel MA. Synthesis of d-1,2-dideoxy-1,2-difluoro-myo-inositol 3,4,5,6-tetrakisphosphate and its enantiomer as analogues of myo-inositol 3,4,5,6-tetrakisphosphate Carbohydrate Research. 309: 337-343. DOI: 10.1016/S0008-6215(98)00146-3  0.01
1997 Hondal RJ, Riddle SR, Kravchuk AV, Zhao Z, Liao H, Bruzik KS, Tsai MD. Phosphatidylinositol-specific phospholipase C: Kinetic and stereochemical evidence for an interaction between arginine-69 and the phosphate group of phosphatidylinositol Biochemistry. 36: 6633-6642. PMID 9184143 DOI: 10.1021/Bi962866G  1
1997 Ho MW, Shears SB, Bruzik KS, Duszyk M, French AS. Ins(3,4,5,6)P4 specifically inhibits a receptor-mediated Ca2+-dependent Cl- current in CFPAC-1 cells. The American Journal of Physiology. 272: C1160-8. PMID 9142840 DOI: 10.1152/Ajpcell.1997.272.4.C1160  1
1997 Bruzik KS, Nyholm PG. NMR study of the conformation of galactocerebroside in bilayers and solution: galactose reorientation during the metastable-stable gel transition. Biochemistry. 36: 566-75. PMID 9012672 DOI: 10.1021/Bi962204R  0.01
1997 Tan Z, Bruzik KS, Shears SB. Properties of the inositol 3,4,5,6-tetrakisphosphate 1-kinase purified from rat liver. Regulation of enzyme activity by inositol 1,3,4-trisphosphate. The Journal of Biological Chemistry. 272: 2285-90. PMID 8999935 DOI: 10.1074/Jbc.272.4.2285  0.08
1997 Hondal RJ, Zhao Z, Riddle SR, Kravchuk AV, Liao H, Bruzik KS, Tsai MD. Phosphatidylinositol-specific phospholipase C. 3. Elucidation of the catalytic mechanism and comparison with ribonuclease A Journal of the American Chemical Society. 119: 9933-9934. DOI: 10.1021/Ja9714402  1
1997 Bruzik KS, Harwood JS. Conformational Study of Phospholipids in Crystalline State and Hydrated Bilayers by13C and31P CP-MAS NMR Journal of the American Chemical Society. 119: 6629-6637. DOI: 10.1021/Ja970720E  0.01
1997 Hondal RJ, Bruzik KS, Zhao Z, Tsai MD. Mechanism of phosphatidylinositol-phospholipase C. 2. Reversal of a thio effect by site-directed mutagenesis [17] Journal of the American Chemical Society. 119: 5477-5478. DOI: 10.1021/Ja964217Y  1
1997 Mihai C, Mataka J, Riddle S, Tsai MD, Bruzik KS. Synthesis of enantiomerically pure phosphorothiolate assay substrate for phosphatidylinositol-specific phospholipase C Bioorganic and Medicinal Chemistry Letters. 7: 1235-1238. DOI: 10.1016/S0960-894X(97)00197-2  1
1997 Kubiak RJ, Bruzik KS. SYNTHESIS OF PHOSPHOROTHIOATE ANALOGS OF PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE Bioorganic & Medicinal Chemistry Letters. 7: 1231-1234. DOI: 10.1016/S0960-894X(97)00196-0  0.01
1996 Xie W, Kaetzel MA, Bruzik KS, Dedman JR, Shears SB, Nelson DJ. Inositol 3,4,5,6-tetrakisphosphate inhibits the calmodulin-dependent protein kinase H-activated chloride conductance in T84 colonic epithelial cells Journal of Biological Chemistry. 271: 14092-14097. PMID 8662902 DOI: 10.1074/Jbc.271.24.14092  1
1996 Kubiak R, Bruzik K. General Synthesis of Phosphatidylinositol Phosphates Phosphorus, Sulfur, and Silicon and the Related Elements. 111: 70-70. DOI: 10.1080/10426509608054699  0.12
1996 Zhiwen G, Bruzik K. Enzymatic Synthesis of Inositol Phosphodiesters Using Phosphatidylinositol-Specific Phospholipase C Phosphorus, Sulfur, and Silicon and the Related Elements. 111: 69-69. DOI: 10.1080/10426509608054698  0.01
1996 Bhamare N, Wang Y, Tsai MD, Bruzik KS. Design, Synthesis And Biochemical Applications Of Analogs Of Phosphatidylinositol Phosphorus Sulfur and Silicon and the Related Elements. 109: 317-320. DOI: 10.1080/10426509608046262  1
1996 Bruzik KS, Guan Z, Riddle S, Tsai M. Synthesis of Inositol Phosphodiesters by Phospholipase C-Catalyzed Transesterification† Journal of the American Chemical Society. 118: 7679-7688. DOI: 10.1021/Ja9616084  0.01
1995 Bruzik KS, Kubiak RJ. General synthesis of phosphatidylinositol 3-phosphates Tetrahedron Letters. 36: 2415-2418. DOI: 10.1016/0040-4039(95)00317-6  0.01
1994 Bruzik KS, Hakeem AA, Tsai MD. Are D- and L-chiro-phosphoinositides substrates of phosphatidylinositol-specific phospholipase C? Biochemistry. 33: 8367-8374. PMID 8031771 DOI: 10.1021/Bi00193A026  1
1994 Bruzik KS, Tsai MD. Toward the mechanism of phosphoinositide-specific phospholipases C. Bioorganic & Medicinal Chemistry. 2: 49-72. PMID 7922124 DOI: 10.1016/S0968-0896(00)82002-7  1
1992 Bruzik KS, Morocho AM, Jhon DY, Rhee SG, Tsai MD. Phospholipids chiral at phosphorus. Stereochemical mechanism for the formation of inositol 1-phosphate catalyzed by phosphatidylinositol-specific phospholipase C. Biochemistry. 31: 5183-93. PMID 1318746 DOI: 10.1021/Bi00137A014  1
1992 Bruzik KS, Tsai MD. Efficient and systematic syntheses of enantiomerically pure and regiospecifically protected myo-inositols Journal of the American Chemical Society. 114: 6361-6374. DOI: 10.1021/Ja00042A011  0.28
1992 Bruzik KS, Myers J, Tsai M. Practical synthesis of enantiomerically pure myo-inositol derivatives Tetrahedron Letters. 33: 1009-1012. DOI: 10.1016/S0040-4039(00)91846-X  0.04
1992 Pietrusiewicz K, Salamończyk GM, Bruzik KS, Wieczorek W. The synthesis of homochiral inositol phosphates from myo-inositol Tetrahedron. 48: 5523-5542. DOI: 10.1016/S0040-4020(01)88305-8  0.01
1991 Bruzik KS, Tsai MD. Phospholipase stereospecificity at phosphorus. Methods in Enzymology. 197: 258-69. PMID 1646930 DOI: 10.1016/0076-6879(91)97151-N  1
1991 Knopik P, Bruzik KS, Stec WJ. AN IMPROVED SYNTHESIS OF 6-(O-PHOSPHORYLCHOLINE)HYDROXYHEXANOIC ACID Organic Preparations and Procedures International. 23: 214-216. DOI: 10.1080/00304949109458318  0.01
1990 Bruzik KS, Sobon B, Salamonczyk GM. Nuclear magnetic resonance study of sphingomyelin bilayers. Biochemistry. 29: 4017-21. PMID 2354174 DOI: 10.1021/Bi00468A032  0.01
1990 Bruzik KS, Salamonczyk GM, Sobon B. 13C CP-MAS study of the gel phases of 1,2-dipalmitoylphosphatidylcholine. Biochimica Et Biophysica Acta. 1023: 143-6. PMID 2337426 DOI: 10.1016/0005-2736(90)90020-O  0.01
1990 Bruzik KS, Grajkowski A, Lesnikowski ZJ, Salamonczyk GM, Stec WJ. Conformation of Diastereomers of Adenosine Cyclic 3′, 5′-Phosphorothioate Nucleosides and Nucleotides. 9: 827-836. DOI: 10.1080/15257779008043148  0.01
1990 Bruzik KS, Salamończyk GM, Soboń B. From Molecular Conformation to Phospholipid Bilayer Organization Phosphorus, Sulfur, and Silicon and the Related Elements. 51: 39-42. DOI: 10.1080/10426509008040677  0.01
1990 Bruzik KS, Stec WJ. Reversible oxidation of phosphylthionates and phosphylselenonates with trifluoroacetic anhydride The Journal of Organic Chemistry. 55: 6131-6135. DOI: 10.1021/Jo00312A018  0.01
1990 M.Salamonczyk G, S.Bruzik K. The synthesis of diastereomers of phosphorothioate analogue of dipalmitoylphosphatidylinositol Tetrahedron Letters. 31: 2015-2016. DOI: 10.1016/S0040-4039(00)88903-0  0.01
1990 Bruzik KS, Salamonczyk GM, Sobon B. Erratum: 13C CP-MAS study of the gel phases of 1,2-dipalmitoylphosphatidylcholine (BBAMEM 70647) (Biochimica e Biophysica Acta, 1023, (1990) 143-146) Biochimica Et Biophysica Acta. 1023. DOI: 10.1016/0005-2736(90)90144-D  0.01
1990 BRUZIK KS, SALAMONCZYK GM. ChemInform Abstract: Synthesis of the Enantiomeric 1,4,5,6-Tetra-O-benzyl-myo-inositols. Cheminform. 21. DOI: 10.1002/chin.199023296  0.01
1990 ANTKOWIAK R, ANTKOWIAK WZ, BRUZIK K. ChemInform Abstract: The Structure of Sultone Formed in Reychler′s Reaction. Cheminform. 21. DOI: 10.1002/chin.199013053  0.08
1989 Antkowiak R, Antkowiak WZ, Bruzik K. The structure of sultone formed in reychler's reaction Tetrahedron. 45: 7515-7522. DOI: 10.1016/S0040-4020(01)89214-0  0.04
1989 Bruzik KS, Salamończyk GM. Synthesis of the enantiomeric 1,4,5,6-tetra-O-benzyl-myo inositols Carbohydrate Research. 195: 67-73. DOI: 10.1016/0008-6215(89)85089-X  0.01
1988 Bruzik KS. Conformation of the polar headgroup of sphingomyelin and its analogues. Biochimica Et Biophysica Acta. 939: 315-26. PMID 3355820 DOI: 10.1016/0005-2736(88)90076-4  0.01
1988 Bruzik KS, Stec WJ. ALKOXYPHOSPHONIUM SALT INTERMEDIATES IN THE THIONO-THIOLO REARRANGEMENT OF PHOSPHYLTHIONATES IN PROTIC ACID MEDIA Phosphorous and Sulfur and the Related Elements. 35: 229-240. DOI: 10.1080/03086648808074326  0.01
1988 Bruzik KS. Synthesis and spectral properties of chemically and stereochemically homogeneous sphingomyelin and its analogues Journal of the Chemical Society-Perkin Transactions 1. 423-431. DOI: 10.1039/P19880000423  0.01
1988 BRUZIK KS. ChemInform Abstract: Synthesis and Spectral Properties of Chemically and Stereochemically Homogeneous Sphingomyelin and Its Analogues. Cheminform. 19. DOI: 10.1002/chin.198824364  0.01
1987 Bruzik KS, Tsai MD. A calorimetric study of the thermotropic behavior of pure sphingomyelin diastereomers. Biochemistry. 26: 5364-8. PMID 3676257 DOI: 10.1021/Bi00391A022  1
1987 BRUZIK KS, SALAMONCZYK G, STEC WJ. ChemInform Abstract: A General Method for the Synthesis of Glycerophospholipids. Cheminform. 18. DOI: 10.1002/chin.198701330  0.01
1986 Bruzik KS, Salamonczyk G, Stec WJ. A general method for the synthesis of glycerophospholipids The Journal of Organic Chemistry. 51: 2368-2370. DOI: 10.1021/Jo00362A035  0.01
1986 BRUZIK KS. ChemInform Abstract: The Synthesis and Absolute Configuration of Thiosphingomyelins. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198631340  0.01
1985 Tsai TC, Hart J, Jiang RT, Bruzik K, Tsai MD. Phospholipids chiral at phosphorus. Use of chiral thiophosphatidylcholine to study the metal-binding properties of bee venom phospholipase A2. Biochemistry. 24: 3180-8. PMID 3839681 DOI: 10.1021/Bi00334A016  0.2
1984 Bruzik K, Tsai MD. Phospholipids chiral at phosphorus. Synthesis of chiral phosphatidylcholine and stereochemistry of phospholipase D. Biochemistry. 23: 1656-61. PMID 6722117 DOI: 10.1021/Bi00303A012  0.36
1984 Bruzik K, Tsai MD. Phospholipids chiral at phosphorus. 5. Synthesis and configurational analysis of chiral [17O,18O]phosphatidylethanolamine Journal of the American Chemical Society. 106: 747-754. DOI: 10.1021/Ja00315A049  0.12
1984 BRUZIK K, TSAI M. ChemInform Abstract: PHOSPHOLIPIDS CHIRAL AT PHOSPHORUS. 5. SYNTHESIS AND CONFIGURATIONAL ANALYSIS S OF CHIRAL (17O,18O)PHOSPHATIDYLETHANOLAMINE Chemischer Informationsdienst. 15. DOI: 10.1002/chin.198419336  0.04
1983 Bruzik K, Jiang RT, Tsai MD. Phospholipids chiral at phosphorus. Preparation and spectral properties of chiral thiophospholipids. Biochemistry. 22: 2478-86. PMID 6688028 DOI: 10.1021/Bi00279A026  0.64
1983 Bruzik KS, Jiang R, Tsai M. Phospholipids chiral at phosphorus. synthesis, absolute configurations and applications Phosphorus and Sulfur and the Related Elements. 18: 369-372. DOI: 10.1080/03086648308076042  0.04
1983 Tsai MD, Jiang RT, Bruzik K. Phospholipids chiral at phosphorus. 4. Could membranes be chiral at phosphorus? Journal of the American Chemical Society. 105: 2478-2480. DOI: 10.1021/Ja00346A064  0.32
1983 SAMMONS RD, FREY PA, BRUZIK K, TSAI M. ChemInform Abstract: EFFECTS OF OXYGEN-17 AND OXYGEN-18 ON PHOSPHORUS-31 NMR: FURTHER INVESTIGATION AND APPLICATIONS Chemischer Informationsdienst. 14. DOI: 10.1002/chin.198346047  0.01
1983 Sammons RD, Frey PA, Bruzik K, Tsai MD. Effects of oxygen-17 and oxygen-18 on phosphorus-31 NMR: further investigation and applications Journal of the American Chemical Society. 105: 5455-5461. DOI: 10.1002/Chin.198346047  0.2
1983 TSAI M, JIANG R, BRUZIK K. ChemInform Abstract: PHOSPHOLIPIDS CHIRAL AT PHOSPHORUS. 4. COULD MEMBRANES BE CHIRAL AT PHOSPHORUS? Chemischer Informationsdienst. 14. DOI: 10.1002/chin.198331271  0.04
1982 Bruzik K, Gupte SM, Tsai MD. Phospholipids chiral at phosphorus. 2. Preparation, property, and application of chiral thiophospholipids Journal of the American Chemical Society. 104: 4682-4684. DOI: 10.1021/Ja00381A033  0.24
1982 BRUZIK K, GUPTE SM, TSAI M. ChemInform Abstract: PHOSPHOLIPIDS CHIRAL AT PHOSPHORUS. 2. PREPARATION, PROPERTY, AND APPLICATION N OF CHIRAL THIOPHOSPHOLIPIDS Chemischer Informationsdienst. 13. DOI: 10.1002/chin.198247347  0.04
1982 BRUZIK K, TSAI M. ChemInform Abstract: PHOSPHOLIPIDS CHIRAL AT PHOSPHORUS. 1. STEREOCHEMISTRY OF TRANSPHOSPHATIDYLATION CATALYZED BY PHOSPHOLIPASE D Chemischer Informationsdienst. 13. DOI: 10.1002/chin.198221245  0.01
1982 Bruzik K, Tsai MD. Phospholipids chiral at phosphorus. 1. Stereochemistry of transphosphatidylation catalyzed by phospholipase D Journal of the American Chemical Society. 104: 863-865. DOI: 10.1002/Chin.198221245  0.24
1981 Bruzik K, Stec WJ. Stereochemistry and product distribution in the thiono-thiolo rearrangement of phosphorothioic esters. 4. Role of leaving-group solvation The Journal of Organic Chemistry. 46: 1625-1630. DOI: 10.1021/jo00321a019  0.08
1981 Bruzik K, Stec WJ. Thiono-thiolo rearrangement and solvolysis of the secondary alkyl phosphorothionates. 3 The Journal of Organic Chemistry. 46: 1618-1624. DOI: 10.1021/Jo00321A018  0.04
1981 BRUZIK K, STEC WJ. ChemInform Abstract: STEREOCHEMISTRY AND PRODUCT DISTRIBUTION IN THE THIONO-THIOLO REARRANGEMENT OF PHOSPHOROTHIOIC ESTERS. 4. ROLE OF LEAVING-GROUP SOLVATION Chemischer Informationsdienst. 12. DOI: 10.1002/chin.198136292  0.01
1981 BRUZIK K, STEC WJ. ChemInform Abstract: THIONO-THIOLO REARRANGEMENT AND SOLVOLYSIS OF THE SECONDARY ALKYL PHOSPHOROTHIONATES. 3 Chemischer Informationsdienst. 12. DOI: 10.1002/chin.198136291  0.12
1980 BRUZIK K, STEC WJ. ChemInform Abstract: STEREOCHEMISTRY OF THIONO-THIOLO REARRANGEMENT OF PHOSPHOROTHIOIC ESTERS. 2 Chemischer Informationsdienst. 11. DOI: 10.1002/chin.198014098  0.01
1979 Bruzik K, Stec WJ. Stereochemistry of thiono-thiolo rearrangement of phosphorothioic esters. 2 The Journal of Organic Chemistry. 44: 4488-4492. DOI: 10.1021/Jo00393A005  0.01
1976 Stec WJ, Uzanski B, Bruzik K, Michalski J. Correction. Protic Acid Catalyzed Thiono-Thiolo Rearrangements of Phosphorus Esters. The Journal of Organic Chemistry. 41: 4051-4052. DOI: 10.1021/Jo00887A616  0.01
1976 Stec WJ, Uznanski B, Bruzik K, Michalski J. Protic acid catalyzed thiono-thiolo rearrangements of phosphorus esters The Journal of Organic Chemistry. 41: 1291-1293. DOI: 10.1021/Jo00869A058  0.01
1976 STEC WJ, UZNANSKI B, BRUZIK K, MICHALSKI J. ChemInform Abstract: PROTIC ACID CATALYZED THIONO-THIOLO REARRANGEMENTS OF PHOSPHORUS ESTERS Chemischer Informationsdienst. 7: no-no. DOI: 10.1002/chin.197630279  0.01
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