| Year |
Citation |
Score |
| 2024 |
Yeo D, Zars Fisher EL, Khosla S, Farr JN, Westendorf JJ. Hdac3-deficiency increases senescence-associated distention of satellite DNA and telomere-associated foci in osteoprogenitor cells. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 38843356 DOI: 10.1093/jbmr/zjae085 |
0.4 |
|
| 2023 |
Torres HM, Hinojosa L, VanCleave AM, Rodezno T, Westendorf JJ, Tao J. Hdac1 and Hdac2 positively regulate Notch1 gain-of-function pathogenic signaling in committed osteoblasts of male mice. Birth Defects Research. PMID 37921375 DOI: 10.1002/bdr2.2266 |
0.446 |
|
| 2023 |
Torres HM, Yeo D, Westendorf JJ. Pulling rank with RNA: RANKL promotes the association of PGC-1β/RNA complexes with NCoR/HDAC3 to activate gene expression in osteoclasts. Molecular Cell. 83: 3397-3399. PMID 37802020 DOI: 10.1016/j.molcel.2023.09.012 |
0.33 |
|
| 2022 |
Taylor EL, Weaver SR, Lorang IM, Arnold KM, Bradley EW, Marron Fernandez de Velasco E, Wickman K, Westendorf JJ. GIRK3 deletion facilitates kappa opioid signaling in chondrocytes, delays vascularization and promotes bone lengthening in mice. Bone. 159: 116391. PMID 35314385 DOI: 10.1016/j.bone.2022.116391 |
0.401 |
|
| 2021 |
Weaver SR, Taylor EL, Zars EL, Arnold KM, Bradley EW, Westendorf JJ. Pleckstrin homology (PH) domain and leucine rich repeat phosphatase 1 (Phlpp1) suppresses parathyroid hormone receptor 1 (Pth1r) expression and signaling during bone growth. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 34086369 DOI: 10.1002/jbmr.4340 |
0.3 |
|
| 2021 |
Weaver SR, Taylor EL, Zars EL, Arnold KM, Bradley EW, Westendorf JJ. PH domain and leucine rich repeat phosphatase 1 (Phlpp1) suppresses parathyroid hormone receptor 1 (Pth1r) expression and signaling during bone growth. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 33434347 DOI: 10.1002/jbmr.4248 |
0.374 |
|
| 2021 |
Taylor EL, Westendorf JJ. Histone Mutations and Bone Cancers. Advances in Experimental Medicine and Biology. 1283: 53-62. PMID 33155137 DOI: 10.1007/978-981-15-8104-5_4 |
0.353 |
|
| 2020 |
Molstad DHH, Mattson AM, Begun DL, Westendorf JJ, Bradley EW. Hdac3 regulates bone modeling by suppressing osteoclast responsiveness to RANKL. The Journal of Biological Chemistry. 295: 17713-17723. PMID 33454009 DOI: 10.1074/jbc.RA120.013573 |
0.472 |
|
| 2020 |
Molstad DHH, Zars E, Norton A, Mansky KC, Westendorf JJ, Bradley EW. Hdac3 deletion in myeloid progenitor cells enhances bone healing in females and limits osteoclast fusion via Pmepa1. Scientific Reports. 10: 21804. PMID 33311522 DOI: 10.1038/s41598-020-78364-5 |
0.457 |
|
| 2020 |
Molstad DHH, Mattson AM, Begun DL, Westendorf JJ, Bradley EW. Hdac3 regulates bone modeling by suppressing osteoclast responsiveness to RANKL. The Journal of Biological Chemistry. PMID 33012705 DOI: 10.1074/jbc.RA120.013573 |
0.47 |
|
| 2020 |
Dudakovic A, Samsonraj RM, Paradise CR, Galeano-Garces C, Mol MO, Galeano-Garces D, Zan P, Galvan ML, Hevesi M, Pichurin O, Thaler R, Begun DL, Kloen P, Karperien M, Larson AN, ... Westendorf JJ, et al. Inhibition of the epigenetic suppressor EZH2 primes osteogenic differentiation mediated by BMP2. The Journal of Biological Chemistry. PMID 32332097 DOI: 10.1074/jbc.RA119.011685 |
0.438 |
|
| 2019 |
Berent TE, Dorschner JM, Craig TA, Drake MT, Westendorf JJ, Kumar R. Lung tumor cells inhibit bone mineralization and osteoblast activity. Biochemical and Biophysical Research Communications. PMID 31537378 DOI: 10.1016/J.Bbrc.2019.09.045 |
0.38 |
|
| 2019 |
Mattson AM, Begun DL, Molstad DHH, Meyer MA, Oursler MJ, Westendorf JJ, Bradley EW. Deficiency in the phosphatase PHLPP1 suppresses osteoclast-mediated bone resorption and enhances bone formation in mice. The Journal of Biological Chemistry. PMID 31189651 DOI: 10.1074/Jbc.Ra119.007660 |
0.405 |
|
| 2018 |
Camilleri E, Dudakovic A, Riester SM, Galeano-Garces C, Paradise CR, Bradley EW, McGee-Lawrence ME, Im HJ, Karperien M, Krych AJ, Westendorf JJ, Larson AN, van Wijnen AJ. Loss of histone methyltransferase Ezh2 stimulates an osteogenic transcriptional program in chondrocytes but does not affect cartilage development. The Journal of Biological Chemistry. PMID 30327434 DOI: 10.1074/Jbc.Ra118.003909 |
0.397 |
|
| 2018 |
Sterner RM, Kremer KN, Dudakovic A, Westendorf JJ, van Wijnen AJ, Hedin KE. Tissue-Nonspecific Alkaline Phosphatase Is Required for MC3T3 Osteoblast-Mediated Protection of Acute Myeloid Leukemia Cells from Apoptosis. Journal of Immunology (Baltimore, Md. : 1950). PMID 29914885 DOI: 10.4049/jimmunol.1800174 |
0.465 |
|
| 2018 |
Dudakovic A, Camilleri E, Paradise CR, Samsonraj RM, Gluscevic M, Paggi CA, Begun DL, Khani F, Pichurin O, Ahmed FS, Elsayed R, Elsalanty M, McGee-Lawrence ME, Karperien M, Riester SM, ... ... Westendorf JJ, et al. Enhancer of zeste homolog 2 (Ezh2) controls bone formation and cell cycle progression during osteogenesis in mice. The Journal of Biological Chemistry. PMID 29899112 DOI: 10.1074/Jbc.Ra118.002983 |
0.43 |
|
| 2018 |
Pierce JL, Begun DL, Westendorf JJ, McGee-Lawrence ME. Defining osteoblast and adipocyte lineages in the bone marrow. Bone. PMID 29782940 DOI: 10.1016/J.Bone.2018.05.019 |
0.432 |
|
| 2018 |
Castillejo Becerra CM, Mattson AM, Molstad DHH, Lorang IM, Westendorf JJ, Bradley EW. DNA methylation and FoxO3a regulate PHLPP1 expression in chondrocytes. Journal of Cellular Biochemistry. PMID 29775231 DOI: 10.1002/jcb.27056 |
0.377 |
|
| 2018 |
Nakatani T, Chen T, Johnson J, Westendorf JJ, Partridge NC. The deletion of Hdac4 in mouse osteoblasts influences both catabolic and anabolic effects in bone. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 29544022 DOI: 10.1002/Jbmr.3422 |
0.4 |
|
| 2018 |
Bowles B, Sterner RM, Kremer KN, Dudakovic A, Westendorf JJ, Van Wijnen AJ, Hedin KE. 2559 Role of tissue non-specific alkaline phosphatase (TNAP) in promoting the survival of acute myeloid leukemia (AML) cells within the bone marrow microenvironment Journal of Clinical and Translational Science. 2: 26-27. DOI: 10.1017/cts.2018.119 |
0.408 |
|
| 2017 |
Sterner RM, Kremer KN, Al-Kali A, Patnaik MM, Gangat N, Litzow MR, Kaufmann SH, Westendorf JJ, van Wijnen AJ, Hedin KE. Histone deacetylase inhibitors reduce differentiating osteoblast-mediated protection of acute myeloid leukemia cells from cytarabine. Oncotarget. 8: 94569-94579. PMID 29212250 DOI: 10.18632/Oncotarget.21809 |
0.419 |
|
| 2017 |
Yang Y, Bai Y, He Y, Zhao Y, Chen J, Ma L, Pan Y, Hinten M, Zhang J, Karnes RJ, Kohli M, Westendorf JJ, Li B, Zhu R, Huang H, et al. PTEN loss promotes intratumoral androgen synthesis and tumor microenvironment remodeling via aberrant activation of RUNX2 in castration-resistant prostate cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29167276 DOI: 10.1158/1078-0432.CCR-17-2006 |
0.301 |
|
| 2017 |
McGee-Lawrence ME, Pierce JL, Yu K, Culpepper NR, Bradley EW, Westendorf JJ. Loss of Hdac3 in osteoprogenitors increases bone expression of osteoprotegerin, improving systemic insulin sensitivity. Journal of Cellular Physiology. PMID 28840938 DOI: 10.1002/Jcp.26148 |
0.303 |
|
| 2017 |
Feigenson M, Shull LC, Taylor EL, Camilleri ET, Reister SM, van Wijnen AJ, Bradley EW, Westendorf JJ. Histone deacetylase 3 deletion in mesenchymal progenitor cells hinders long bone development. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 28782836 DOI: 10.1002/jbmr.3236 |
0.493 |
|
| 2017 |
Dudakovic A, Gluscevic M, Paradise CR, Dudakovic H, Khani F, Thaler R, Ahmed FS, Li X, Dietz AB, Stein GS, Montecino MA, Deyle DR, Westendorf JJ, van Wijnen AJ. Profiling of human epigenetic regulators using a semi-automated real-time qPCR platform validated by next generation sequencing. Gene. PMID 28132772 DOI: 10.1016/J.Gene.2017.01.019 |
0.362 |
|
| 2016 |
Dudakovic A, Camilleri ET, Riester SM, Paradise CR, Gluscevic M, O'Toole TM, Thaler R, Evans JM, Yan H, Subramaniam M, Hawse JR, Stein GS, Montecino MA, McGee-Lawrence ME, Westendorf JJ, et al. Enhancer of Zeste Homolog 2 Inhibition Stimulates Bone Formation and Mitigates Bone Loss Due to Ovariectomy in Skeletally Mature Mice. The Journal of Biological Chemistry. PMID 27758858 DOI: 10.1074/Jbc.M116.740571 |
0.454 |
|
| 2016 |
Carpio LR, Bradley EW, McGee-Lawrence ME, Weivoda MM, Poston DD, Dudakovic A, Xu M, Tchkonia T, Kirkland JL, van Wijnen AJ, Oursler MJ, Westendorf JJ. Histone deacetylase 3 supports endochondral bone formation by controlling cytokine signaling and matrix remodeling. Science Signaling. 9: ra79. PMID 27507649 DOI: 10.1126/Scisignal.Aaf3273 |
0.454 |
|
| 2016 |
Weivoda MM, Ruan M, Pederson L, Hachfeld C, Davey RA, Zajac JD, Westendorf JJ, Khosla S, Oursler MJ. Osteoclast TGF-β Receptor Signaling Induces Wnt1 Secretion and Couples Bone Resorption to Bone Formation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 31: 76-85. PMID 26108893 DOI: 10.1002/Jbmr.2586 |
0.363 |
|
| 2016 |
Sterner R, Kremer K, Dudakovic A, Kaufmann S, Westendorf J, Wijnen Av, Hedin K. Abstract 3292: Manipulating osteoblast differentiation in order to inhibit protection of AML cells within the bone marrow Cancer Research. 76: 3292-3292. DOI: 10.1158/1538-7445.Am2016-3292 |
0.526 |
|
| 2015 |
Kremer KN, Dudakovic A, Hess AD, Smith BD, Karp JE, Kaufmann SH, Westendorf JJ, van Wijnen AJ, Hedin KE. Histone deacetylase inhibitors target the leukemic microenvironment by enhancing a Nherf1-Protein Phosphatase 1α-TAZ signaling pathway in osteoblasts. The Journal of Biological Chemistry. PMID 26491017 DOI: 10.1074/Jbc.M115.668160 |
0.46 |
|
| 2015 |
Dudakovic A, Camilleri ET, Xu F, Riester SM, McGee-Lawrence ME, Bradley EW, Paradise CR, Lewallen EA, Thaler R, Deyle DR, Larson AN, Lewallen DG, Dietz AB, Stein GS, Montecino MA, ... Westendorf JJ, et al. Epigenetic Control of Skeletal Development by the Histone Methyltransferase Ezh2. The Journal of Biological Chemistry. PMID 26424790 DOI: 10.1074/Jbc.M115.672345 |
0.496 |
|
| 2015 |
Nicks KM, Fujita K, Fraser D, McGregor U, Drake MT, McGee-Lawrence ME, Westendorf JJ, Monroe DG, Khosla S. Deletion of Estrogen Receptor Beta in Osteoprogenitor Cells Increases Trabecular but Not Cortical Bone Mass in Female Mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 26418452 DOI: 10.1002/Jbmr.2723 |
0.391 |
|
| 2015 |
Bradley EW, Carpio LR, van Wijnen AJ, McGee-Lawrence ME, Westendorf JJ. Histone Deacetylases in Bone Development and Skeletal Disorders. Physiological Reviews. 95: 1359-81. PMID 26378079 DOI: 10.1152/Physrev.00004.2015 |
0.423 |
|
| 2015 |
McGee-Lawrence ME, Carpio LR, Schulze RJ, Pierce JL, McNiven MA, Farr JN, Khosla S, Oursler MJ, Westendorf JJ. Hdac3-Deficiency Increases Marrow Adiposity and Induces Lipid Storage and Glucocorticoid Metabolism in Osteo-Chondroprogenitor Cells. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 26211746 DOI: 10.1002/Jbmr.2602 |
0.435 |
|
| 2015 |
Weivoda MM, Ruan M, Hachfeld CM, Pederson L, Howe A, Davey RA, Zajac JD, Kobayashi Y, Williams BO, Westendorf JJ, Khosla S, Oursler MJ. Wnt Signaling Inhibits Osteoclast Differentiation by Activating Canonical and Noncanonical cAMP/PKA Pathways. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 26189772 DOI: 10.1002/Jbmr.2599 |
0.446 |
|
| 2015 |
Bradley EW, Carpio LR, Newton AC, Westendorf JJ. Deletion of the PH-domain and Leucine-rich Repeat Protein Phosphatase 1 (Phlpp1) Increases Fibroblast Growth Factor (Fgf) 18 Expression and Promotes Chondrocyte Proliferation. The Journal of Biological Chemistry. 290: 16272-80. PMID 25953896 DOI: 10.1074/Jbc.M114.612937 |
0.342 |
|
| 2015 |
Gordon JA, Stein JL, Westendorf JJ, van Wijnen AJ. Chromatin modifiers and histone modifications in bone formation, regeneration, and therapeutic intervention for bone-related disease. Bone. PMID 25836763 DOI: 10.1016/j.bone.2015.03.011 |
0.363 |
|
| 2015 |
Zou L, Kidwai FK, Kopher RA, Motl J, Kellum CA, Westendorf JJ, Kaufman DS. Use of RUNX2 expression to identify osteogenic progenitor cells derived from human embryonic stem cells. Stem Cell Reports. 4: 190-8. PMID 25680477 DOI: 10.1016/j.stemcr.2015.01.008 |
0.386 |
|
| 2015 |
Bradley EW, Carpio LR, Olson EN, Westendorf JJ. Histone deacetylase 7 (Hdac7) suppresses chondrocyte proliferation and β-catenin activity during endochondral ossification. The Journal of Biological Chemistry. 290: 118-26. PMID 25389289 DOI: 10.1074/Jbc.M114.596247 |
0.354 |
|
| 2015 |
Dudakovic A, Camilleri ET, Lewallen EA, McGee-Lawrence ME, Riester SM, Kakar S, Montecino M, Stein GS, Ryoo HM, Dietz AB, Westendorf JJ, van Wijnen AJ. Histone deacetylase inhibition destabilizes the multi-potent state of uncommitted adipose-derived mesenchymal stromal cells. Journal of Cellular Physiology. 230: 52-62. PMID 24912092 DOI: 10.1002/Jcp.24680 |
0.374 |
|
| 2014 |
McGee-Lawrence ME, Carpio LR, Bradley EW, Dudakovic A, Lian JB, van Wijnen AJ, Kakar S, Hsu W, Westendorf JJ. Runx2 is required for early stages of endochondral bone formation but delays final stages of bone repair in Axin2-deficient mice. Bone. 66: 277-86. PMID 24973690 DOI: 10.1016/J.Bone.2014.06.022 |
0.342 |
|
| 2014 |
Dudakovic A, Camilleri E, Riester SM, Lewallen EA, Kvasha S, Chen X, Radel DJ, Anderson JM, Nair AA, Evans JM, Krych AJ, Smith J, Deyle DR, Stein JL, Stein GS, ... ... Westendorf JJ, et al. High-resolution molecular validation of self-renewal and spontaneous differentiation in clinical-grade adipose-tissue derived human mesenchymal stem cells. Journal of Cellular Biochemistry. 115: 1816-28. PMID 24905804 DOI: 10.1002/Jcb.24852 |
0.314 |
|
| 2014 |
Kremer KN, Dudakovic A, McGee-Lawrence ME, Philips RL, Hess AD, Smith BD, van Wijnen AJ, Karp JE, Kaufmann SH, Westendorf JJ, Hedin KE. Osteoblasts protect AML cells from SDF-1-induced apoptosis. Journal of Cellular Biochemistry. 115: 1128-37. PMID 24851270 DOI: 10.1002/Jcb.24755 |
0.385 |
|
| 2014 |
Bledsoe KL, McGee-Lawrence ME, Camilleri ET, Wang X, Riester SM, van Wijnen AJ, Oliveira AM, Westendorf JJ. RUNX3 facilitates growth of Ewing sarcoma cells. Journal of Cellular Physiology. 229: 2049-56. PMID 24812032 DOI: 10.1002/Jcp.24663 |
0.452 |
|
| 2014 |
Ryan ZC, Craig TA, Salisbury JL, Carpio LR, McGee-Lawrence M, Westendorf JJ, Kumar R. Enhanced prostacyclin formation and Wnt signaling in sclerostin deficient osteocytes and bone Biochemical and Biophysical Research Communications. 448: 83-88. PMID 24780398 DOI: 10.1016/J.Bbrc.2014.04.092 |
0.401 |
|
| 2014 |
Hinton DJ, McGee-Lawrence ME, Lee MR, Kwong HK, Westendorf JJ, Choi DS. Aberrant bone density in aging mice lacking the adenosine transporter ENT1. Plos One. 9: e88818. PMID 24586402 DOI: 10.1371/Journal.Pone.0088818 |
0.341 |
|
| 2013 |
Dudakovic A, Evans JM, Li Y, Middha S, McGee-Lawrence ME, van Wijnen AJ, Westendorf JJ. Histone deacetylase inhibition promotes osteoblast maturation by altering the histone H4 epigenome and reduces Akt phosphorylation. The Journal of Biological Chemistry. 288: 28783-91. PMID 23940046 DOI: 10.1074/Jbc.M113.489732 |
0.443 |
|
| 2013 |
Ota K, Quint P, Weivoda MM, Ruan M, Pederson L, Westendorf JJ, Khosla S, Oursler MJ. Transforming growth factor beta 1 induces CXCL16 and leukemia inhibitory factor expression in osteoclasts to modulate migration of osteoblast progenitors. Bone. 57: 68-75. PMID 23891907 DOI: 10.1016/J.Bone.2013.07.023 |
0.361 |
|
| 2013 |
Ota K, Quint P, Ruan M, Pederson L, Westendorf JJ, Khosla S, Oursler MJ. TGF-β induces Wnt10b in osteoclasts from female mice to enhance coupling to osteoblasts. Endocrinology. 154: 3745-52. PMID 23861379 DOI: 10.1210/En.2013-1272 |
0.357 |
|
| 2013 |
Ota K, Quint P, Ruan M, Pederson L, Westendorf JJ, Khosla S, Oursler MJ. Sclerostin is expressed in osteoclasts from aged mice and reduces osteoclast-mediated stimulation of mineralization. Journal of Cellular Biochemistry. 114: 1901-7. PMID 23494985 DOI: 10.1002/Jcb.24537 |
0.349 |
|
| 2013 |
Bradley EW, Carpio LR, Westendorf JJ. Histone deacetylase 3 suppression increases PH domain and leucine-rich repeat phosphatase (Phlpp)1 expression in chondrocytes to suppress Akt signaling and matrix secretion. The Journal of Biological Chemistry. 288: 9572-82. PMID 23408427 DOI: 10.1074/jbc.M112.423723 |
0.36 |
|
| 2013 |
McGee-Lawrence ME, Li X, Bledsoe KL, Wu H, Hawse JR, Subramaniam M, Razidlo DF, Stensgard BA, Stein GS, van Wijnen AJ, Lian JB, Hsu W, Westendorf JJ. Runx2 protein represses Axin2 expression in osteoblasts and is required for craniosynostosis in Axin2-deficient mice. The Journal of Biological Chemistry. 288: 5291-302. PMID 23300083 DOI: 10.1074/Jbc.M112.414995 |
0.382 |
|
| 2013 |
Quint P, Ruan M, Pederson L, Kassem M, Westendorf JJ, Khosla S, Oursler MJ. Sphingosine 1-phosphate (S1P) receptors 1 and 2 coordinately induce mesenchymal cell migration through S1P activation of complementary kinase pathways. The Journal of Biological Chemistry. 288: 5398-406. PMID 23300082 DOI: 10.1074/Jbc.M112.413583 |
0.378 |
|
| 2013 |
McGee-Lawrence ME, Bradley EW, Dudakovic A, Carlson SW, Ryan ZC, Kumar R, Dadsetan M, Yaszemski MJ, Chen Q, An KN, Westendorf JJ. Histone deacetylase 3 is required for maintenance of bone mass during aging. Bone. 52: 296-307. PMID 23085085 DOI: 10.1016/J.Bone.2012.10.015 |
0.424 |
|
| 2012 |
Monroe DG, McGee-Lawrence ME, Oursler MJ, Westendorf JJ. Update on Wnt signaling in bone cell biology and bone disease. Gene. 492: 1-18. PMID 22079544 DOI: 10.1016/J.Gene.2011.10.044 |
0.362 |
|
| 2011 |
Bradley EW, McGee-Lawrence ME, Westendorf JJ. Hdac-mediated control of endochondral and intramembranous ossification. Critical Reviews in Eukaryotic Gene Expression. 21: 101-13. PMID 22077150 DOI: 10.1615/Critreveukargeneexpr.V21.I2.10 |
0.348 |
|
| 2011 |
Hoeppner LH, Secreto FJ, Razidlo DF, Whitney TJ, Westendorf JJ. Lef1DeltaN binds beta-catenin and increases osteoblast activity and trabecular bone mass. The Journal of Biological Chemistry. 286: 10950-9. PMID 21270130 DOI: 10.1074/Jbc.M110.165100 |
0.766 |
|
| 2011 |
McGee-Lawrence ME, McCleary-Wheeler AL, Secreto FJ, Razidlo DF, Zhang M, Stensgard BA, Li X, Stein GS, Lian JB, Westendorf JJ. Suberoylanilide hydroxamic acid (SAHA; vorinostat) causes bone loss by inhibiting immature osteoblasts. Bone. 48: 1117-26. PMID 21255693 DOI: 10.1016/J.Bone.2011.01.007 |
0.429 |
|
| 2011 |
McGee-Lawrence ME, Westendorf JJ. Histone deacetylases in skeletal development and bone mass maintenance. Gene. 474: 1-11. PMID 21185361 DOI: 10.1016/J.Gene.2010.12.003 |
0.48 |
|
| 2010 |
Pratap J, Akech J, Wixted JJ, Szabo G, Hussain S, McGee-Lawrence ME, Li X, Bedard K, Dhillon RJ, van Wijnen AJ, Stein JL, Stein GS, Westendorf JJ, Lian JB. The histone deacetylase inhibitor, vorinostat, reduces tumor growth at the metastatic bone site and associated osteolysis, but promotes normal bone loss. Molecular Cancer Therapeutics. 9: 3210-20. PMID 21159607 DOI: 10.1158/1535-7163.Mct-10-0572 |
0.334 |
|
| 2010 |
Khosla S, Westendorf JJ, Mödder UI. Concise review: Insights from normal bone remodeling and stem cell-based therapies for bone repair. Stem Cells (Dayton, Ohio). 28: 2124-8. PMID 20960512 DOI: 10.1002/stem.546 |
0.332 |
|
| 2010 |
Li X, McGee-Lawrence ME, Decker M, Westendorf JJ. The Ewing's sarcoma fusion protein, EWS-FLI, binds Runx2 and blocks osteoblast differentiation. Journal of Cellular Biochemistry. 111: 933-43. PMID 20665663 DOI: 10.1002/Jcb.22782 |
0.428 |
|
| 2010 |
Razidlo DF, Whitney TJ, Casper ME, McGee-Lawrence ME, Stensgard BA, Li X, Secreto FJ, Knutson SK, Hiebert SW, Westendorf JJ. Histone deacetylase 3 depletion in osteo/chondroprogenitor cells decreases bone density and increases marrow fat. Plos One. 5: e11492. PMID 20628553 DOI: 10.1371/Journal.Pone.0011492 |
0.424 |
|
| 2010 |
Li X, Decker M, Westendorf JJ. TEThered to Runx: novel binding partners for runx factors. Blood Cells, Molecules & Diseases. 45: 82-5. PMID 20362478 DOI: 10.1016/j.bcmd.2010.03.002 |
0.388 |
|
| 2010 |
Shimizu E, Selvamurugan N, Westendorf JJ, Olson EN, Partridge NC. HDAC4 represses matrix metalloproteinase-13 transcription in osteoblastic cells, and parathyroid hormone controls this repression Journal of Biological Chemistry. 285: 9616-9626. PMID 20097749 DOI: 10.1074/Jbc.M109.094862 |
0.418 |
|
| 2010 |
Jensen ED, Gopalakrishnan R, Westendorf JJ. Regulation of gene expression in osteoblasts. Biofactors (Oxford, England). 36: 25-32. PMID 20087883 DOI: 10.1002/Biof.72 |
0.428 |
|
| 2010 |
Jensen ED, Pham L, Billington CJ, Espe K, Carlson AE, Westendorf JJ, Petryk A, Gopalakrishnan R, Mansky K. Bone morphogenic protein 2 directly enhances differentiation of murine osteoclast precursors. Journal of Cellular Biochemistry. 109: 672-82. PMID 20039313 DOI: 10.1002/Jcb.22462 |
0.475 |
|
| 2009 |
Undale AH, Westendorf JJ, Yaszemski MJ, Khosla S. Mesenchymal stem cells for bone repair and metabolic bone diseases. Mayo Clinic Proceedings. 84: 893-902. PMID 19797778 DOI: 10.4065/84.10.893 |
0.314 |
|
| 2009 |
Hoeppner LH, Secreto F, Jensen ED, Li X, Kahler RA, Westendorf JJ. Runx2 and bone morphogenic protein 2 regulate the expression of an alternative Lef1 transcript during osteoblast maturation. Journal of Cellular Physiology. 221: 480-9. PMID 19650108 DOI: 10.1002/Jcp.21879 |
0.821 |
|
| 2009 |
Secreto FJ, Hoeppner LH, Westendorf JJ. Wnt signaling during fracture repair. Current Osteoporosis Reports. 7: 64-9. PMID 19631031 DOI: 10.1007/S11914-009-0012-5 |
0.699 |
|
| 2009 |
Li X, Hoeppner LH, Jensen ED, Gopalakrishnan R, Westendorf JJ. Co-activator activator (CoAA) prevents the transcriptional activity of Runt domain transcription factors. Journal of Cellular Biochemistry. 108: 378-87. PMID 19585539 DOI: 10.1002/Jcb.22263 |
0.777 |
|
| 2009 |
Hoeppner LH, Secreto FJ, Westendorf JJ. Wnt signaling as a therapeutic target for bone diseases. Expert Opinion On Therapeutic Targets. 13: 485-96. PMID 19335070 DOI: 10.1517/14728220902841961 |
0.728 |
|
| 2009 |
Jensen ED, Gopalakrishnan R, Westendorf JJ. Bone morphogenic protein 2 activates protein kinase D to regulate histone deacetylase 7 localization and repression of Runx2. The Journal of Biological Chemistry. 284: 2225-34. PMID 19029091 DOI: 10.1074/Jbc.M800586200 |
0.445 |
|
| 2008 |
Pederson L, Ruan M, Westendorf JJ, Khosla S, Oursler MJ. Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate. Proceedings of the National Academy of Sciences of the United States of America. 105: 20764-9. PMID 19075223 DOI: 10.1073/Pnas.0805133106 |
0.425 |
|
| 2008 |
Kahler RA, Yingst SM, Hoeppner LH, Jensen ED, Krawczak D, Oxford JT, Westendorf JJ. Collagen 11a1 is indirectly activated by lymphocyte enhancer-binding factor 1 (Lef1) and negatively regulates osteoblast maturation. Matrix Biology : Journal of the International Society For Matrix Biology. 27: 330-8. PMID 18280717 DOI: 10.1016/J.Matbio.2008.01.002 |
0.807 |
|
| 2008 |
Khosla S, Westendorf JJ, Oursler MJ. Building bone to reverse osteoporosis and repair fractures. The Journal of Clinical Investigation. 118: 421-8. PMID 18246192 DOI: 10.1172/Jci33612 |
0.304 |
|
| 2008 |
Jensen ED, Schroeder TM, Bailey J, Gopalakrishnan R, Westendorf JJ. Histone deacetylase 7 associates with Runx2 and represses its activity during osteoblast maturation in a deacetylation-independent manner. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 23: 361-72. PMID 17997710 DOI: 10.1359/Jbmr.071104 |
0.791 |
|
| 2008 |
Jensen ED, Niu L, Caretti G, Nicol SM, Teplyuk N, Stein GS, Sartorelli V, van Wijnen AJ, Fuller-Pace FV, Westendorf JJ. p68 (Ddx5) interacts with Runx2 and regulates osteoblast differentiation. Journal of Cellular Biochemistry. 103: 1438-51. PMID 17960593 DOI: 10.1002/Jcb.21526 |
0.386 |
|
| 2007 |
Schroeder TM, Nair AK, Staggs R, Lamblin AF, Westendorf JJ. Gene profile analysis of osteoblast genes differentially regulated by histone deacetylase inhibitors. Bmc Genomics. 8: 362. PMID 17925016 DOI: 10.1186/1471-2164-8-362 |
0.794 |
|
| 2007 |
Galindo M, Kahler RA, Teplyuk NM, Stein JL, Lian JB, Stein GS, Westendorf JJ, van Wijnen AJ. Cell cycle related modulations in Runx2 protein levels are independent of lymphocyte enhancer-binding factor 1 (Lef1) in proliferating osteoblasts. Journal of Molecular Histology. 38: 501-6. PMID 17885813 DOI: 10.1007/S10735-007-9143-0 |
0.815 |
|
| 2007 |
Jensen ED, Nair AK, Westendorf JJ. Histone deacetylase co-repressor complex control of Runx2 and bone formation. Critical Reviews in Eukaryotic Gene Expression. 17: 187-96. PMID 17725488 |
0.544 |
|
| 2007 |
Shimizu E, Selvamurugan N, Westendorf JJ, Partridge NC. Parathyroid hormone regulates histone deacetylases in osteoblasts. Annals of the New York Academy of Sciences. 1116: 349-53. PMID 17656568 DOI: 10.1196/Annals.1402.037 |
0.441 |
|
| 2007 |
Tolar J, Nauta AJ, Osborn MJ, Panoskaltsis Mortari A, McElmurry RT, Bell S, Xia L, Zhou N, Riddle M, Schroeder TM, Westendorf JJ, McIvor RS, Hogendoorn PC, Szuhai K, Oseth L, et al. Sarcoma derived from cultured mesenchymal stem cells. Stem Cells (Dayton, Ohio). 25: 371-9. PMID 17038675 DOI: 10.1634/Stemcells.2005-0620 |
0.758 |
|
| 2007 |
Westendorf JJ, Hoeppner L. Administration of zoledronic acid enhances the effects of docetaxel on growth of prostate cancer in the bone environment Urologic Oncology: Seminars and Original Investigations. 25: 182. DOI: 10.1016/J.Urolonc.2006.12.008 |
0.71 |
|
| 2007 |
Westendorf JJ, Hoeppner L. Glucocorticoids suppress tumor angiogenesis and in vivo growth of prostate cancer cells Urologic Oncology: Seminars and Original Investigations. 25: 181-182. DOI: 10.1016/J.Urolonc.2006.12.007 |
0.659 |
|
| 2007 |
Westendorf JJ, Hoeppner L. Down-regulation of androgen receptor by 3,3′-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in both hormone-sensitive LNCaP and insensitive C4-2B prostate cancer cells Urologic Oncology: Seminars and Original Investigations. 25: 180-181. DOI: 10.1016/J.Urolonc.2006.12.006 |
0.678 |
|
| 2007 |
Westendorf JJ, Hoeppner L. Intrinsic apoptotic and thioredoxin pathways in human prostate cancer cell response to histone deacetylase inhibitor Urologic Oncology: Seminars and Original Investigations. 25: 180. DOI: 10.1016/J.Urolonc.2006.12.005 |
0.661 |
|
| 2007 |
Westendorf JJ, Hoeppner L. Type I collagen receptor ({alpha}2{beta}1) signaling promotes the growth of human prostate cancer cells within the bone Urologic Oncology: Seminars and Original Investigations. 25: 179-180. DOI: 10.1016/J.Urolonc.2006.12.004 |
0.7 |
|
| 2006 |
Westendorf JJ. Transcriptional co-repressors of Runx2. Journal of Cellular Biochemistry. 98: 54-64. PMID 16440320 DOI: 10.1002/jcb.20805 |
0.326 |
|
| 2006 |
Kahler RA, Galindo M, Lian J, Stein GS, van Wijnen AJ, Westendorf JJ. Lymphocyte enhancer-binding factor 1 (Lef1) inhibits terminal differentiation of osteoblasts. Journal of Cellular Biochemistry. 97: 969-83. PMID 16267835 DOI: 10.1002/Jcb.20702 |
0.842 |
|
| 2005 |
Schroeder TM, Westendorf JJ. Histone deacetylase inhibitors promote osteoblast maturation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 2254-63. PMID 16294278 DOI: 10.1359/Jbmr.050813 |
0.786 |
|
| 2005 |
Dong X, Lutz W, Schroeder TM, Bachman LA, Westendorf JJ, Kumar R, Griffin MD. Regulation of relB in dendritic cells by means of modulated association of vitamin D receptor and histone deacetylase 3 with the promoter. Proceedings of the National Academy of Sciences of the United States of America. 102: 16007-12. PMID 16239345 DOI: 10.1073/Pnas.0506516102 |
0.746 |
|
| 2005 |
Schroeder TM, Jensen ED, Westendorf JJ. Runx2: a master organizer of gene transcription in developing and maturing osteoblasts. Birth Defects Research. Part C, Embryo Today : Reviews. 75: 213-25. PMID 16187316 DOI: 10.1002/Bdrc.20043 |
0.825 |
|
| 2005 |
Tolar J, Osborn MJ, Panoskaltsis-Mortari A, McElmurry RT, Bell S, Xia L, Riddle M, Schroeder TM, Westendorf JJ, McIvor RS, Oseth L, Hirsch B, Yant SR, Kay MA, Peister A, et al. Mesenchymal Cancer Cells Can Arise from Ex Vivo Modified Mesenchymal Stem Cells. Blood. 106: 4326-4326. DOI: 10.1182/Blood.V106.11.4326.4326 |
0.765 |
|
| 2004 |
Westendorf JJ, Kahler RA, Schroeder TM. Wnt signaling in osteoblasts and bone diseases. Gene. 341: 19-39. PMID 15474285 DOI: 10.1016/J.Gene.2004.06.044 |
0.784 |
|
| 2004 |
Schroeder TM, Kahler RA, Li X, Westendorf JJ. Histone deacetylase 3 interacts with runx2 to repress the osteocalcin promoter and regulate osteoblast differentiation. The Journal of Biological Chemistry. 279: 41998-2007. PMID 15292260 DOI: 10.1074/Jbc.M403702200 |
0.811 |
|
| 2004 |
Zeliadt NA, Warmka JK, Winston SE, Kahler R, Westendorf JJ, Mauro LJ, Wattenberg EV. Tumor promoter-induced MMP-13 gene expression in a model of initiated epidermis. Biochemical and Biophysical Research Communications. 317: 570-7. PMID 15063796 DOI: 10.1016/J.Bbrc.2004.03.081 |
0.784 |
|
| 2004 |
Bose N, Kahler RA, Li X, Bergemann H, Rajkumar V, Westendorf J, Anna M. Impaired In Vitro Osteogenesis in Multiple Myeloma Bone Marrow Osteoprogenitor Cells. Blood. 104: 2349-2349. DOI: 10.1182/Blood.V104.11.2349.2349 |
0.831 |
|
| 2003 |
Kahler RA, Westendorf JJ. Lymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter. The Journal of Biological Chemistry. 278: 11937-44. PMID 12551949 DOI: 10.1074/Jbc.M211443200 |
0.825 |
|
| 2002 |
Westendorf JJ, Zaidi SK, Cascino JE, Kahler R, van Wijnen AJ, Lian JB, Yoshida M, Stein GS, Li X. Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter. Molecular and Cellular Biology. 22: 7982-92. PMID 12391164 DOI: 10.1128/Mcb.22.22.7982-7992.2002 |
0.811 |
|
| 2002 |
Yeung F, Law WK, Yeh CH, Westendorf JJ, Zhang Y, Wang R, Kao C, Chung LW. Regulation of human osteocalcin promoter in hormone-independent human prostate cancer cells. The Journal of Biological Chemistry. 277: 2468-76. PMID 11684680 DOI: 10.1074/Jbc.M105947200 |
0.344 |
|
| 2000 |
Melnick AM, Westendorf JJ, Polinger A, Carlile GW, Arai S, Ball HJ, Lutterbach B, Hiebert SW, Licht JD. The ETO protein disrupted in t(8;21)-associated acute myeloid leukemia is a corepressor for the promyelocytic leukemia zinc finger protein Molecular and Cellular Biology. 20: 2075-2086. PMID 10688654 DOI: 10.1128/Mcb.20.6.2075-2086.2000 |
0.328 |
|
| 1999 |
Westendorf JJ, Hiebert SW. Mammalian runt-domain proteins and their roles in hematopoiesis, osteogenesis, and leukemia Journal of Cellular Biochemistry. 76: 51-58. PMID 10629103 DOI: 10.1002/(Sici)1097-4644(1999)75:32+<51::Aid-Jcb7>3.0.Co;2-S |
0.41 |
|
| 1997 |
Lenny N, Westendorf JJ, Hiebert SW. Transcriptional regulation during myelopoiesis Molecular Biology Reports. 24: 157-168. PMID 9291089 DOI: 10.1023/A:1006859700409 |
0.392 |
|
| 1995 |
Westendorf J, Lammert J, Jelinek D. Expression and function of Fas (APO-1/CD95) in patient myeloma cells and myeloma cell lines Blood. 85: 3566-3576. DOI: 10.1182/Blood.V85.12.3566.Bloodjournal85123566 |
0.327 |
|
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