Jennifer Westendorf - Publications

Affiliations: 
University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Molecular Biology, Biochemistry

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Year Citation  Score
2023 Torres HM, Hinojosa L, VanCleave AM, Rodezno T, Westendorf JJ, Tao J. Hdac1 and Hdac2 positively regulate Notch1 gain-of-function pathogenic signaling in committed osteoblasts of male mice. Birth Defects Research. PMID 37921375 DOI: 10.1002/bdr2.2266  0.446
2023 Torres HM, Yeo D, Westendorf JJ. Pulling rank with RNA: RANKL promotes the association of PGC-1β/RNA complexes with NCoR/HDAC3 to activate gene expression in osteoclasts. Molecular Cell. 83: 3397-3399. PMID 37802020 DOI: 10.1016/j.molcel.2023.09.012  0.33
2022 Taylor EL, Weaver SR, Lorang IM, Arnold KM, Bradley EW, Marron Fernandez de Velasco E, Wickman K, Westendorf JJ. GIRK3 deletion facilitates kappa opioid signaling in chondrocytes, delays vascularization and promotes bone lengthening in mice. Bone. 159: 116391. PMID 35314385 DOI: 10.1016/j.bone.2022.116391  0.401
2021 Weaver SR, Taylor EL, Zars EL, Arnold KM, Bradley EW, Westendorf JJ. Pleckstrin homology (PH) domain and leucine rich repeat phosphatase 1 (Phlpp1) suppresses parathyroid hormone receptor 1 (Pth1r) expression and signaling during bone growth. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 34086369 DOI: 10.1002/jbmr.4340  0.3
2021 Weaver SR, Taylor EL, Zars EL, Arnold KM, Bradley EW, Westendorf JJ. PH domain and leucine rich repeat phosphatase 1 (Phlpp1) suppresses parathyroid hormone receptor 1 (Pth1r) expression and signaling during bone growth. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 33434347 DOI: 10.1002/jbmr.4248  0.374
2021 Taylor EL, Westendorf JJ. Histone Mutations and Bone Cancers. Advances in Experimental Medicine and Biology. 1283: 53-62. PMID 33155137 DOI: 10.1007/978-981-15-8104-5_4  0.353
2020 Molstad DHH, Mattson AM, Begun DL, Westendorf JJ, Bradley EW. Hdac3 regulates bone modeling by suppressing osteoclast responsiveness to RANKL. The Journal of Biological Chemistry. 295: 17713-17723. PMID 33454009 DOI: 10.1074/jbc.RA120.013573  0.472
2020 Molstad DHH, Zars E, Norton A, Mansky KC, Westendorf JJ, Bradley EW. Hdac3 deletion in myeloid progenitor cells enhances bone healing in females and limits osteoclast fusion via Pmepa1. Scientific Reports. 10: 21804. PMID 33311522 DOI: 10.1038/s41598-020-78364-5  0.457
2020 Molstad DHH, Mattson AM, Begun DL, Westendorf JJ, Bradley EW. Hdac3 regulates bone modeling by suppressing osteoclast responsiveness to RANKL. The Journal of Biological Chemistry. PMID 33012705 DOI: 10.1074/jbc.RA120.013573  0.47
2020 Dudakovic A, Samsonraj RM, Paradise CR, Galeano-Garces C, Mol MO, Galeano-Garces D, Zan P, Galvan ML, Hevesi M, Pichurin O, Thaler R, Begun DL, Kloen P, Karperien M, Larson AN, ... Westendorf JJ, et al. Inhibition of the epigenetic suppressor EZH2 primes osteogenic differentiation mediated by BMP2. The Journal of Biological Chemistry. PMID 32332097 DOI: 10.1074/jbc.RA119.011685  0.438
2019 Berent TE, Dorschner JM, Craig TA, Drake MT, Westendorf JJ, Kumar R. Lung tumor cells inhibit bone mineralization and osteoblast activity. Biochemical and Biophysical Research Communications. PMID 31537378 DOI: 10.1016/J.Bbrc.2019.09.045  0.38
2019 Mattson AM, Begun DL, Molstad DHH, Meyer MA, Oursler MJ, Westendorf JJ, Bradley EW. Deficiency in the phosphatase PHLPP1 suppresses osteoclast-mediated bone resorption and enhances bone formation in mice. The Journal of Biological Chemistry. PMID 31189651 DOI: 10.1074/Jbc.Ra119.007660  0.405
2018 Camilleri E, Dudakovic A, Riester SM, Galeano-Garces C, Paradise CR, Bradley EW, McGee-Lawrence ME, Im HJ, Karperien M, Krych AJ, Westendorf JJ, Larson AN, van Wijnen AJ. Loss of histone methyltransferase Ezh2 stimulates an osteogenic transcriptional program in chondrocytes but does not affect cartilage development. The Journal of Biological Chemistry. PMID 30327434 DOI: 10.1074/Jbc.Ra118.003909  0.397
2018 Sterner RM, Kremer KN, Dudakovic A, Westendorf JJ, van Wijnen AJ, Hedin KE. Tissue-Nonspecific Alkaline Phosphatase Is Required for MC3T3 Osteoblast-Mediated Protection of Acute Myeloid Leukemia Cells from Apoptosis. Journal of Immunology (Baltimore, Md. : 1950). PMID 29914885 DOI: 10.4049/jimmunol.1800174  0.465
2018 Dudakovic A, Camilleri E, Paradise CR, Samsonraj RM, Gluscevic M, Paggi CA, Begun DL, Khani F, Pichurin O, Ahmed FS, Elsayed R, Elsalanty M, McGee-Lawrence ME, Karperien M, Riester SM, ... ... Westendorf JJ, et al. Enhancer of zeste homolog 2 (Ezh2) controls bone formation and cell cycle progression during osteogenesis in mice. The Journal of Biological Chemistry. PMID 29899112 DOI: 10.1074/Jbc.Ra118.002983  0.429
2018 Pierce JL, Begun DL, Westendorf JJ, McGee-Lawrence ME. Defining osteoblast and adipocyte lineages in the bone marrow. Bone. PMID 29782940 DOI: 10.1016/J.Bone.2018.05.019  0.431
2018 Castillejo Becerra CM, Mattson AM, Molstad DHH, Lorang IM, Westendorf JJ, Bradley EW. DNA methylation and FoxO3a regulate PHLPP1 expression in chondrocytes. Journal of Cellular Biochemistry. PMID 29775231 DOI: 10.1002/jcb.27056  0.377
2018 Nakatani T, Chen T, Johnson J, Westendorf JJ, Partridge NC. The deletion of Hdac4 in mouse osteoblasts influences both catabolic and anabolic effects in bone. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 29544022 DOI: 10.1002/Jbmr.3422  0.4
2018 Bowles B, Sterner RM, Kremer KN, Dudakovic A, Westendorf JJ, Van Wijnen AJ, Hedin KE. 2559 Role of tissue non-specific alkaline phosphatase (TNAP) in promoting the survival of acute myeloid leukemia (AML) cells within the bone marrow microenvironment Journal of Clinical and Translational Science. 2: 26-27. DOI: 10.1017/cts.2018.119  0.408
2017 Sterner RM, Kremer KN, Al-Kali A, Patnaik MM, Gangat N, Litzow MR, Kaufmann SH, Westendorf JJ, van Wijnen AJ, Hedin KE. Histone deacetylase inhibitors reduce differentiating osteoblast-mediated protection of acute myeloid leukemia cells from cytarabine. Oncotarget. 8: 94569-94579. PMID 29212250 DOI: 10.18632/Oncotarget.21809  0.419
2017 Yang Y, Bai Y, He Y, Zhao Y, Chen J, Ma L, Pan Y, Hinten M, Zhang J, Karnes RJ, Kohli M, Westendorf JJ, Li B, Zhu R, Huang H, et al. PTEN loss promotes intratumoral androgen synthesis and tumor microenvironment remodeling via aberrant activation of RUNX2 in castration-resistant prostate cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29167276 DOI: 10.1158/1078-0432.CCR-17-2006  0.301
2017 McGee-Lawrence ME, Pierce JL, Yu K, Culpepper NR, Bradley EW, Westendorf JJ. Loss of Hdac3 in osteoprogenitors increases bone expression of osteoprotegerin, improving systemic insulin sensitivity. Journal of Cellular Physiology. PMID 28840938 DOI: 10.1002/Jcp.26148  0.303
2017 Feigenson M, Shull LC, Taylor EL, Camilleri ET, Reister SM, van Wijnen AJ, Bradley EW, Westendorf JJ. Histone deacetylase 3 deletion in mesenchymal progenitor cells hinders long bone development. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 28782836 DOI: 10.1002/jbmr.3236  0.493
2017 Dudakovic A, Gluscevic M, Paradise CR, Dudakovic H, Khani F, Thaler R, Ahmed FS, Li X, Dietz AB, Stein GS, Montecino MA, Deyle DR, Westendorf JJ, van Wijnen AJ. Profiling of human epigenetic regulators using a semi-automated real-time qPCR platform validated by next generation sequencing. Gene. PMID 28132772 DOI: 10.1016/J.Gene.2017.01.019  0.362
2016 Dudakovic A, Camilleri ET, Riester SM, Paradise CR, Gluscevic M, O'Toole TM, Thaler R, Evans JM, Yan H, Subramaniam M, Hawse JR, Stein GS, Montecino MA, McGee-Lawrence ME, Westendorf JJ, et al. Enhancer of Zeste Homolog 2 Inhibition Stimulates Bone Formation and Mitigates Bone Loss Due to Ovariectomy in Skeletally Mature Mice. The Journal of Biological Chemistry. PMID 27758858 DOI: 10.1074/Jbc.M116.740571  0.454
2016 Carpio LR, Bradley EW, McGee-Lawrence ME, Weivoda MM, Poston DD, Dudakovic A, Xu M, Tchkonia T, Kirkland JL, van Wijnen AJ, Oursler MJ, Westendorf JJ. Histone deacetylase 3 supports endochondral bone formation by controlling cytokine signaling and matrix remodeling. Science Signaling. 9: ra79. PMID 27507649 DOI: 10.1126/Scisignal.Aaf3273  0.454
2016 Weivoda MM, Ruan M, Pederson L, Hachfeld C, Davey RA, Zajac JD, Westendorf JJ, Khosla S, Oursler MJ. Osteoclast TGF-β Receptor Signaling Induces Wnt1 Secretion and Couples Bone Resorption to Bone Formation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 31: 76-85. PMID 26108893 DOI: 10.1002/Jbmr.2586  0.363
2016 Sterner R, Kremer K, Dudakovic A, Kaufmann S, Westendorf J, Wijnen Av, Hedin K. Abstract 3292: Manipulating osteoblast differentiation in order to inhibit protection of AML cells within the bone marrow Cancer Research. 76: 3292-3292. DOI: 10.1158/1538-7445.Am2016-3292  0.526
2015 Kremer KN, Dudakovic A, Hess AD, Smith BD, Karp JE, Kaufmann SH, Westendorf JJ, van Wijnen AJ, Hedin KE. Histone deacetylase inhibitors target the leukemic microenvironment by enhancing a Nherf1-Protein Phosphatase 1α-TAZ signaling pathway in osteoblasts. The Journal of Biological Chemistry. PMID 26491017 DOI: 10.1074/Jbc.M115.668160  0.46
2015 Dudakovic A, Camilleri ET, Xu F, Riester SM, McGee-Lawrence ME, Bradley EW, Paradise CR, Lewallen EA, Thaler R, Deyle DR, Larson AN, Lewallen DG, Dietz AB, Stein GS, Montecino MA, ... Westendorf JJ, et al. Epigenetic Control of Skeletal Development by the Histone Methyltransferase Ezh2. The Journal of Biological Chemistry. PMID 26424790 DOI: 10.1074/Jbc.M115.672345  0.495
2015 Nicks KM, Fujita K, Fraser D, McGregor U, Drake MT, McGee-Lawrence ME, Westendorf JJ, Monroe DG, Khosla S. Deletion of Estrogen Receptor Beta in Osteoprogenitor Cells Increases Trabecular but Not Cortical Bone Mass in Female Mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 26418452 DOI: 10.1002/Jbmr.2723  0.391
2015 Bradley EW, Carpio LR, van Wijnen AJ, McGee-Lawrence ME, Westendorf JJ. Histone Deacetylases in Bone Development and Skeletal Disorders. Physiological Reviews. 95: 1359-81. PMID 26378079 DOI: 10.1152/Physrev.00004.2015  0.423
2015 McGee-Lawrence ME, Carpio LR, Schulze RJ, Pierce JL, McNiven MA, Farr JN, Khosla S, Oursler MJ, Westendorf JJ. Hdac3-Deficiency Increases Marrow Adiposity and Induces Lipid Storage and Glucocorticoid Metabolism in Osteo-Chondroprogenitor Cells. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 26211746 DOI: 10.1002/Jbmr.2602  0.435
2015 Weivoda MM, Ruan M, Hachfeld CM, Pederson L, Howe A, Davey RA, Zajac JD, Kobayashi Y, Williams BO, Westendorf JJ, Khosla S, Oursler MJ. Wnt Signaling Inhibits Osteoclast Differentiation by Activating Canonical and Noncanonical cAMP/PKA Pathways. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 26189772 DOI: 10.1002/Jbmr.2599  0.446
2015 Bradley EW, Carpio LR, Newton AC, Westendorf JJ. Deletion of the PH-domain and Leucine-rich Repeat Protein Phosphatase 1 (Phlpp1) Increases Fibroblast Growth Factor (Fgf) 18 Expression and Promotes Chondrocyte Proliferation. The Journal of Biological Chemistry. 290: 16272-80. PMID 25953896 DOI: 10.1074/Jbc.M114.612937  0.342
2015 Gordon JA, Stein JL, Westendorf JJ, van Wijnen AJ. Chromatin modifiers and histone modifications in bone formation, regeneration, and therapeutic intervention for bone-related disease. Bone. PMID 25836763 DOI: 10.1016/j.bone.2015.03.011  0.363
2015 Zou L, Kidwai FK, Kopher RA, Motl J, Kellum CA, Westendorf JJ, Kaufman DS. Use of RUNX2 expression to identify osteogenic progenitor cells derived from human embryonic stem cells. Stem Cell Reports. 4: 190-8. PMID 25680477 DOI: 10.1016/j.stemcr.2015.01.008  0.386
2015 Bradley EW, Carpio LR, Olson EN, Westendorf JJ. Histone deacetylase 7 (Hdac7) suppresses chondrocyte proliferation and β-catenin activity during endochondral ossification. The Journal of Biological Chemistry. 290: 118-26. PMID 25389289 DOI: 10.1074/Jbc.M114.596247  0.353
2015 Dudakovic A, Camilleri ET, Lewallen EA, McGee-Lawrence ME, Riester SM, Kakar S, Montecino M, Stein GS, Ryoo HM, Dietz AB, Westendorf JJ, van Wijnen AJ. Histone deacetylase inhibition destabilizes the multi-potent state of uncommitted adipose-derived mesenchymal stromal cells. Journal of Cellular Physiology. 230: 52-62. PMID 24912092 DOI: 10.1002/Jcp.24680  0.374
2014 McGee-Lawrence ME, Carpio LR, Bradley EW, Dudakovic A, Lian JB, van Wijnen AJ, Kakar S, Hsu W, Westendorf JJ. Runx2 is required for early stages of endochondral bone formation but delays final stages of bone repair in Axin2-deficient mice. Bone. 66: 277-86. PMID 24973690 DOI: 10.1016/J.Bone.2014.06.022  0.342
2014 Dudakovic A, Camilleri E, Riester SM, Lewallen EA, Kvasha S, Chen X, Radel DJ, Anderson JM, Nair AA, Evans JM, Krych AJ, Smith J, Deyle DR, Stein JL, Stein GS, ... ... Westendorf JJ, et al. High-resolution molecular validation of self-renewal and spontaneous differentiation in clinical-grade adipose-tissue derived human mesenchymal stem cells. Journal of Cellular Biochemistry. 115: 1816-28. PMID 24905804 DOI: 10.1002/Jcb.24852  0.314
2014 Kremer KN, Dudakovic A, McGee-Lawrence ME, Philips RL, Hess AD, Smith BD, van Wijnen AJ, Karp JE, Kaufmann SH, Westendorf JJ, Hedin KE. Osteoblasts protect AML cells from SDF-1-induced apoptosis. Journal of Cellular Biochemistry. 115: 1128-37. PMID 24851270 DOI: 10.1002/Jcb.24755  0.385
2014 Bledsoe KL, McGee-Lawrence ME, Camilleri ET, Wang X, Riester SM, van Wijnen AJ, Oliveira AM, Westendorf JJ. RUNX3 facilitates growth of Ewing sarcoma cells. Journal of Cellular Physiology. 229: 2049-56. PMID 24812032 DOI: 10.1002/Jcp.24663  0.452
2014 Ryan ZC, Craig TA, Salisbury JL, Carpio LR, McGee-Lawrence M, Westendorf JJ, Kumar R. Enhanced prostacyclin formation and Wnt signaling in sclerostin deficient osteocytes and bone Biochemical and Biophysical Research Communications. 448: 83-88. PMID 24780398 DOI: 10.1016/J.Bbrc.2014.04.092  0.401
2014 Hinton DJ, McGee-Lawrence ME, Lee MR, Kwong HK, Westendorf JJ, Choi DS. Aberrant bone density in aging mice lacking the adenosine transporter ENT1. Plos One. 9: e88818. PMID 24586402 DOI: 10.1371/Journal.Pone.0088818  0.341
2013 Dudakovic A, Evans JM, Li Y, Middha S, McGee-Lawrence ME, van Wijnen AJ, Westendorf JJ. Histone deacetylase inhibition promotes osteoblast maturation by altering the histone H4 epigenome and reduces Akt phosphorylation. The Journal of Biological Chemistry. 288: 28783-91. PMID 23940046 DOI: 10.1074/Jbc.M113.489732  0.442
2013 Ota K, Quint P, Weivoda MM, Ruan M, Pederson L, Westendorf JJ, Khosla S, Oursler MJ. Transforming growth factor beta 1 induces CXCL16 and leukemia inhibitory factor expression in osteoclasts to modulate migration of osteoblast progenitors. Bone. 57: 68-75. PMID 23891907 DOI: 10.1016/J.Bone.2013.07.023  0.361
2013 Ota K, Quint P, Ruan M, Pederson L, Westendorf JJ, Khosla S, Oursler MJ. TGF-β induces Wnt10b in osteoclasts from female mice to enhance coupling to osteoblasts. Endocrinology. 154: 3745-52. PMID 23861379 DOI: 10.1210/En.2013-1272  0.357
2013 Ota K, Quint P, Ruan M, Pederson L, Westendorf JJ, Khosla S, Oursler MJ. Sclerostin is expressed in osteoclasts from aged mice and reduces osteoclast-mediated stimulation of mineralization. Journal of Cellular Biochemistry. 114: 1901-7. PMID 23494985 DOI: 10.1002/Jcb.24537  0.349
2013 Bradley EW, Carpio LR, Westendorf JJ. Histone deacetylase 3 suppression increases PH domain and leucine-rich repeat phosphatase (Phlpp)1 expression in chondrocytes to suppress Akt signaling and matrix secretion. The Journal of Biological Chemistry. 288: 9572-82. PMID 23408427 DOI: 10.1074/jbc.M112.423723  0.36
2013 McGee-Lawrence ME, Li X, Bledsoe KL, Wu H, Hawse JR, Subramaniam M, Razidlo DF, Stensgard BA, Stein GS, van Wijnen AJ, Lian JB, Hsu W, Westendorf JJ. Runx2 protein represses Axin2 expression in osteoblasts and is required for craniosynostosis in Axin2-deficient mice. The Journal of Biological Chemistry. 288: 5291-302. PMID 23300083 DOI: 10.1074/Jbc.M112.414995  0.382
2013 Quint P, Ruan M, Pederson L, Kassem M, Westendorf JJ, Khosla S, Oursler MJ. Sphingosine 1-phosphate (S1P) receptors 1 and 2 coordinately induce mesenchymal cell migration through S1P activation of complementary kinase pathways. The Journal of Biological Chemistry. 288: 5398-406. PMID 23300082 DOI: 10.1074/Jbc.M112.413583  0.378
2013 McGee-Lawrence ME, Bradley EW, Dudakovic A, Carlson SW, Ryan ZC, Kumar R, Dadsetan M, Yaszemski MJ, Chen Q, An KN, Westendorf JJ. Histone deacetylase 3 is required for maintenance of bone mass during aging. Bone. 52: 296-307. PMID 23085085 DOI: 10.1016/J.Bone.2012.10.015  0.424
2012 Monroe DG, McGee-Lawrence ME, Oursler MJ, Westendorf JJ. Update on Wnt signaling in bone cell biology and bone disease. Gene. 492: 1-18. PMID 22079544 DOI: 10.1016/J.Gene.2011.10.044  0.362
2011 Bradley EW, McGee-Lawrence ME, Westendorf JJ. Hdac-mediated control of endochondral and intramembranous ossification. Critical Reviews in Eukaryotic Gene Expression. 21: 101-13. PMID 22077150 DOI: 10.1615/Critreveukargeneexpr.V21.I2.10  0.348
2011 Hoeppner LH, Secreto FJ, Razidlo DF, Whitney TJ, Westendorf JJ. Lef1DeltaN binds beta-catenin and increases osteoblast activity and trabecular bone mass. The Journal of Biological Chemistry. 286: 10950-9. PMID 21270130 DOI: 10.1074/Jbc.M110.165100  0.767
2011 McGee-Lawrence ME, McCleary-Wheeler AL, Secreto FJ, Razidlo DF, Zhang M, Stensgard BA, Li X, Stein GS, Lian JB, Westendorf JJ. Suberoylanilide hydroxamic acid (SAHA; vorinostat) causes bone loss by inhibiting immature osteoblasts. Bone. 48: 1117-26. PMID 21255693 DOI: 10.1016/J.Bone.2011.01.007  0.429
2011 McGee-Lawrence ME, Westendorf JJ. Histone deacetylases in skeletal development and bone mass maintenance. Gene. 474: 1-11. PMID 21185361 DOI: 10.1016/J.Gene.2010.12.003  0.479
2010 Pratap J, Akech J, Wixted JJ, Szabo G, Hussain S, McGee-Lawrence ME, Li X, Bedard K, Dhillon RJ, van Wijnen AJ, Stein JL, Stein GS, Westendorf JJ, Lian JB. The histone deacetylase inhibitor, vorinostat, reduces tumor growth at the metastatic bone site and associated osteolysis, but promotes normal bone loss. Molecular Cancer Therapeutics. 9: 3210-20. PMID 21159607 DOI: 10.1158/1535-7163.Mct-10-0572  0.334
2010 Khosla S, Westendorf JJ, Mödder UI. Concise review: Insights from normal bone remodeling and stem cell-based therapies for bone repair. Stem Cells (Dayton, Ohio). 28: 2124-8. PMID 20960512 DOI: 10.1002/stem.546  0.332
2010 Li X, McGee-Lawrence ME, Decker M, Westendorf JJ. The Ewing's sarcoma fusion protein, EWS-FLI, binds Runx2 and blocks osteoblast differentiation. Journal of Cellular Biochemistry. 111: 933-43. PMID 20665663 DOI: 10.1002/Jcb.22782  0.428
2010 Razidlo DF, Whitney TJ, Casper ME, McGee-Lawrence ME, Stensgard BA, Li X, Secreto FJ, Knutson SK, Hiebert SW, Westendorf JJ. Histone deacetylase 3 depletion in osteo/chondroprogenitor cells decreases bone density and increases marrow fat. Plos One. 5: e11492. PMID 20628553 DOI: 10.1371/Journal.Pone.0011492  0.423
2010 Li X, Decker M, Westendorf JJ. TEThered to Runx: novel binding partners for runx factors. Blood Cells, Molecules & Diseases. 45: 82-5. PMID 20362478 DOI: 10.1016/j.bcmd.2010.03.002  0.388
2010 Shimizu E, Selvamurugan N, Westendorf JJ, Olson EN, Partridge NC. HDAC4 represses matrix metalloproteinase-13 transcription in osteoblastic cells, and parathyroid hormone controls this repression Journal of Biological Chemistry. 285: 9616-9626. PMID 20097749 DOI: 10.1074/Jbc.M109.094862  0.418
2010 Jensen ED, Gopalakrishnan R, Westendorf JJ. Regulation of gene expression in osteoblasts. Biofactors (Oxford, England). 36: 25-32. PMID 20087883 DOI: 10.1002/Biof.72  0.427
2010 Jensen ED, Pham L, Billington CJ, Espe K, Carlson AE, Westendorf JJ, Petryk A, Gopalakrishnan R, Mansky K. Bone morphogenic protein 2 directly enhances differentiation of murine osteoclast precursors. Journal of Cellular Biochemistry. 109: 672-82. PMID 20039313 DOI: 10.1002/Jcb.22462  0.475
2009 Undale AH, Westendorf JJ, Yaszemski MJ, Khosla S. Mesenchymal stem cells for bone repair and metabolic bone diseases. Mayo Clinic Proceedings. 84: 893-902. PMID 19797778 DOI: 10.4065/84.10.893  0.314
2009 Hoeppner LH, Secreto F, Jensen ED, Li X, Kahler RA, Westendorf JJ. Runx2 and bone morphogenic protein 2 regulate the expression of an alternative Lef1 transcript during osteoblast maturation. Journal of Cellular Physiology. 221: 480-9. PMID 19650108 DOI: 10.1002/Jcp.21879  0.821
2009 Secreto FJ, Hoeppner LH, Westendorf JJ. Wnt signaling during fracture repair. Current Osteoporosis Reports. 7: 64-9. PMID 19631031 DOI: 10.1007/S11914-009-0012-5  0.701
2009 Li X, Hoeppner LH, Jensen ED, Gopalakrishnan R, Westendorf JJ. Co-activator activator (CoAA) prevents the transcriptional activity of Runt domain transcription factors. Journal of Cellular Biochemistry. 108: 378-87. PMID 19585539 DOI: 10.1002/Jcb.22263  0.778
2009 Hoeppner LH, Secreto FJ, Westendorf JJ. Wnt signaling as a therapeutic target for bone diseases. Expert Opinion On Therapeutic Targets. 13: 485-96. PMID 19335070 DOI: 10.1517/14728220902841961  0.729
2009 Jensen ED, Gopalakrishnan R, Westendorf JJ. Bone morphogenic protein 2 activates protein kinase D to regulate histone deacetylase 7 localization and repression of Runx2. The Journal of Biological Chemistry. 284: 2225-34. PMID 19029091 DOI: 10.1074/Jbc.M800586200  0.445
2008 Pederson L, Ruan M, Westendorf JJ, Khosla S, Oursler MJ. Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate. Proceedings of the National Academy of Sciences of the United States of America. 105: 20764-9. PMID 19075223 DOI: 10.1073/Pnas.0805133106  0.425
2008 Kahler RA, Yingst SM, Hoeppner LH, Jensen ED, Krawczak D, Oxford JT, Westendorf JJ. Collagen 11a1 is indirectly activated by lymphocyte enhancer-binding factor 1 (Lef1) and negatively regulates osteoblast maturation. Matrix Biology : Journal of the International Society For Matrix Biology. 27: 330-8. PMID 18280717 DOI: 10.1016/J.Matbio.2008.01.002  0.807
2008 Khosla S, Westendorf JJ, Oursler MJ. Building bone to reverse osteoporosis and repair fractures. The Journal of Clinical Investigation. 118: 421-8. PMID 18246192 DOI: 10.1172/Jci33612  0.304
2008 Jensen ED, Schroeder TM, Bailey J, Gopalakrishnan R, Westendorf JJ. Histone deacetylase 7 associates with Runx2 and represses its activity during osteoblast maturation in a deacetylation-independent manner. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 23: 361-72. PMID 17997710 DOI: 10.1359/Jbmr.071104  0.791
2008 Jensen ED, Niu L, Caretti G, Nicol SM, Teplyuk N, Stein GS, Sartorelli V, van Wijnen AJ, Fuller-Pace FV, Westendorf JJ. p68 (Ddx5) interacts with Runx2 and regulates osteoblast differentiation. Journal of Cellular Biochemistry. 103: 1438-51. PMID 17960593 DOI: 10.1002/Jcb.21526  0.386
2007 Schroeder TM, Nair AK, Staggs R, Lamblin AF, Westendorf JJ. Gene profile analysis of osteoblast genes differentially regulated by histone deacetylase inhibitors. Bmc Genomics. 8: 362. PMID 17925016 DOI: 10.1186/1471-2164-8-362  0.794
2007 Galindo M, Kahler RA, Teplyuk NM, Stein JL, Lian JB, Stein GS, Westendorf JJ, van Wijnen AJ. Cell cycle related modulations in Runx2 protein levels are independent of lymphocyte enhancer-binding factor 1 (Lef1) in proliferating osteoblasts. Journal of Molecular Histology. 38: 501-6. PMID 17885813 DOI: 10.1007/S10735-007-9143-0  0.815
2007 Jensen ED, Nair AK, Westendorf JJ. Histone deacetylase co-repressor complex control of Runx2 and bone formation. Critical Reviews in Eukaryotic Gene Expression. 17: 187-96. PMID 17725488  0.544
2007 Shimizu E, Selvamurugan N, Westendorf JJ, Partridge NC. Parathyroid hormone regulates histone deacetylases in osteoblasts. Annals of the New York Academy of Sciences. 1116: 349-53. PMID 17656568 DOI: 10.1196/Annals.1402.037  0.441
2007 Tolar J, Nauta AJ, Osborn MJ, Panoskaltsis Mortari A, McElmurry RT, Bell S, Xia L, Zhou N, Riddle M, Schroeder TM, Westendorf JJ, McIvor RS, Hogendoorn PC, Szuhai K, Oseth L, et al. Sarcoma derived from cultured mesenchymal stem cells. Stem Cells (Dayton, Ohio). 25: 371-9. PMID 17038675 DOI: 10.1634/Stemcells.2005-0620  0.758
2007 Westendorf JJ, Hoeppner L. Administration of zoledronic acid enhances the effects of docetaxel on growth of prostate cancer in the bone environment Urologic Oncology: Seminars and Original Investigations. 25: 182. DOI: 10.1016/J.Urolonc.2006.12.008  0.712
2007 Westendorf JJ, Hoeppner L. Glucocorticoids suppress tumor angiogenesis and in vivo growth of prostate cancer cells Urologic Oncology: Seminars and Original Investigations. 25: 181-182. DOI: 10.1016/J.Urolonc.2006.12.007  0.661
2007 Westendorf JJ, Hoeppner L. Down-regulation of androgen receptor by 3,3′-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in both hormone-sensitive LNCaP and insensitive C4-2B prostate cancer cells Urologic Oncology: Seminars and Original Investigations. 25: 180-181. DOI: 10.1016/J.Urolonc.2006.12.006  0.68
2007 Westendorf JJ, Hoeppner L. Intrinsic apoptotic and thioredoxin pathways in human prostate cancer cell response to histone deacetylase inhibitor Urologic Oncology: Seminars and Original Investigations. 25: 180. DOI: 10.1016/J.Urolonc.2006.12.005  0.663
2007 Westendorf JJ, Hoeppner L. Type I collagen receptor ({alpha}2{beta}1) signaling promotes the growth of human prostate cancer cells within the bone Urologic Oncology: Seminars and Original Investigations. 25: 179-180. DOI: 10.1016/J.Urolonc.2006.12.004  0.702
2006 Westendorf JJ. Transcriptional co-repressors of Runx2. Journal of Cellular Biochemistry. 98: 54-64. PMID 16440320 DOI: 10.1002/jcb.20805  0.326
2006 Kahler RA, Galindo M, Lian J, Stein GS, van Wijnen AJ, Westendorf JJ. Lymphocyte enhancer-binding factor 1 (Lef1) inhibits terminal differentiation of osteoblasts. Journal of Cellular Biochemistry. 97: 969-83. PMID 16267835 DOI: 10.1002/Jcb.20702  0.842
2005 Schroeder TM, Westendorf JJ. Histone deacetylase inhibitors promote osteoblast maturation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 2254-63. PMID 16294278 DOI: 10.1359/Jbmr.050813  0.786
2005 Dong X, Lutz W, Schroeder TM, Bachman LA, Westendorf JJ, Kumar R, Griffin MD. Regulation of relB in dendritic cells by means of modulated association of vitamin D receptor and histone deacetylase 3 with the promoter. Proceedings of the National Academy of Sciences of the United States of America. 102: 16007-12. PMID 16239345 DOI: 10.1073/Pnas.0506516102  0.746
2005 Schroeder TM, Jensen ED, Westendorf JJ. Runx2: a master organizer of gene transcription in developing and maturing osteoblasts. Birth Defects Research. Part C, Embryo Today : Reviews. 75: 213-25. PMID 16187316 DOI: 10.1002/Bdrc.20043  0.825
2005 Tolar J, Osborn MJ, Panoskaltsis-Mortari A, McElmurry RT, Bell S, Xia L, Riddle M, Schroeder TM, Westendorf JJ, McIvor RS, Oseth L, Hirsch B, Yant SR, Kay MA, Peister A, et al. Mesenchymal Cancer Cells Can Arise from Ex Vivo Modified Mesenchymal Stem Cells. Blood. 106: 4326-4326. DOI: 10.1182/Blood.V106.11.4326.4326  0.765
2004 Westendorf JJ, Kahler RA, Schroeder TM. Wnt signaling in osteoblasts and bone diseases. Gene. 341: 19-39. PMID 15474285 DOI: 10.1016/J.Gene.2004.06.044  0.785
2004 Schroeder TM, Kahler RA, Li X, Westendorf JJ. Histone deacetylase 3 interacts with runx2 to repress the osteocalcin promoter and regulate osteoblast differentiation. The Journal of Biological Chemistry. 279: 41998-2007. PMID 15292260 DOI: 10.1074/Jbc.M403702200  0.811
2004 Zeliadt NA, Warmka JK, Winston SE, Kahler R, Westendorf JJ, Mauro LJ, Wattenberg EV. Tumor promoter-induced MMP-13 gene expression in a model of initiated epidermis. Biochemical and Biophysical Research Communications. 317: 570-7. PMID 15063796 DOI: 10.1016/J.Bbrc.2004.03.081  0.784
2004 Bose N, Kahler RA, Li X, Bergemann H, Rajkumar V, Westendorf J, Anna M. Impaired In Vitro Osteogenesis in Multiple Myeloma Bone Marrow Osteoprogenitor Cells. Blood. 104: 2349-2349. DOI: 10.1182/Blood.V104.11.2349.2349  0.831
2003 Kahler RA, Westendorf JJ. Lymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter. The Journal of Biological Chemistry. 278: 11937-44. PMID 12551949 DOI: 10.1074/Jbc.M211443200  0.825
2002 Westendorf JJ, Zaidi SK, Cascino JE, Kahler R, van Wijnen AJ, Lian JB, Yoshida M, Stein GS, Li X. Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter. Molecular and Cellular Biology. 22: 7982-92. PMID 12391164 DOI: 10.1128/Mcb.22.22.7982-7992.2002  0.811
2002 Yeung F, Law WK, Yeh CH, Westendorf JJ, Zhang Y, Wang R, Kao C, Chung LW. Regulation of human osteocalcin promoter in hormone-independent human prostate cancer cells. The Journal of Biological Chemistry. 277: 2468-76. PMID 11684680 DOI: 10.1074/Jbc.M105947200  0.344
2000 Melnick AM, Westendorf JJ, Polinger A, Carlile GW, Arai S, Ball HJ, Lutterbach B, Hiebert SW, Licht JD. The ETO protein disrupted in t(8;21)-associated acute myeloid leukemia is a corepressor for the promyelocytic leukemia zinc finger protein Molecular and Cellular Biology. 20: 2075-2086. PMID 10688654 DOI: 10.1128/Mcb.20.6.2075-2086.2000  0.328
1999 Westendorf JJ, Hiebert SW. Mammalian runt-domain proteins and their roles in hematopoiesis, osteogenesis, and leukemia Journal of Cellular Biochemistry. 76: 51-58. PMID 10629103 DOI: 10.1002/(Sici)1097-4644(1999)75:32+<51::Aid-Jcb7>3.0.Co;2-S  0.41
1997 Lenny N, Westendorf JJ, Hiebert SW. Transcriptional regulation during myelopoiesis Molecular Biology Reports. 24: 157-168. PMID 9291089 DOI: 10.1023/A:1006859700409  0.392
1995 Westendorf J, Lammert J, Jelinek D. Expression and function of Fas (APO-1/CD95) in patient myeloma cells and myeloma cell lines Blood. 85: 3566-3576. DOI: 10.1182/Blood.V85.12.3566.Bloodjournal85123566  0.327
Low-probability matches (unlikely to be authored by this person)
2000 Strom DK, John N, Westendorf JJ, Linggi B, Lutterbach B, Downing JR, Lenny N, Hiebert SW. Expression of the AML-1 oncogene shortens the G1 phase of the cell cycle Journal of Biological Chemistry. 275: 3438-3445. PMID 10652337 DOI: 10.1074/Jbc.275.5.3438  0.299
2014 Dudakovic A, Camilleri E, Riester S, Westendorf J, Kakar S, Dietz A, van WA. High-resolution molecular validation of self-renewal and spontaneous differentiation in adipose-tissue derived human mesenchymal stem cells cultured in human platelet lysate Bone Abstracts. DOI: 10.1530/Boneabs.3.Pp135  0.297
2021 Dong Z, Yeo KS, Lopez G, Zhang C, Dankert Eggum EN, Rokita JL, Ung CY, Levee TM, Her ZP, Howe CJ, Hou X, van Ree JH, Li S, He S, Tao T, ... ... Westendorf JJ, et al. GAS7 Deficiency Promotes Metastasis in MYCN-driven Neuroblastoma. Cancer Research. PMID 33602789 DOI: 10.1158/0008-5472.CAN-20-1890  0.296
2009 Krawczak DA, Westendorf JJ, Carlson CS, Lewis JL. Influence of bone morphogenetic protein-2 on the extracellular matrix, material properties, and gene expression of long-term articular chondrocyte cultures: loss of chondrocyte stability. Tissue Engineering. Part A. 15: 1247-55. PMID 18950256 DOI: 10.1089/Ten.Tea.2008.0249  0.295
2023 Torres HM, Arnold KM, Oviedo M, Westendorf JJ, Weaver SR. Inflammatory Processes Affecting Bone Health and Repair. Current Osteoporosis Reports. PMID 37759135 DOI: 10.1007/s11914-023-00824-4  0.294
2019 van Wijnen AJ, Westendorf JJ. Epigenetics as a New Frontier in Orthopedic Regenerative Medicine and Oncology. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 30977555 DOI: 10.1002/jor.24305  0.293
2013 McGee-Lawrence ME, Ryan ZC, Carpio LR, Kakar S, Westendorf JJ, Kumar R. Sclerostin deficient mice rapidly heal bone defects by activating β-catenin and increasing intramembranous ossification. Biochemical and Biophysical Research Communications. 441: 886-90. PMID 24211207 DOI: 10.1016/J.Bbrc.2013.10.155  0.292
2011 Zhang H, Pan Y, Zheng L, Choe C, Lindgren B, Jensen ED, Westendorf JJ, Cheng L, Huang H. FOXO1 inhibits Runx2 transcriptional activity and prostate cancer cell migration and invasion. Cancer Research. 71: 3257-67. PMID 21505104 DOI: 10.1158/0008-5472.CAN-10-2603  0.292
2023 Jachim SK, Zhong J, Ordog T, Lee JH, Bhagwate AV, Nagaraj NK, Westendorf JJ, Passos JF, Matveyenko AV, LeBrasseur NK. BMAL1 modulates senescence programming via AP-1. Aging. 15: 9984-10009. PMID 37819791 DOI: 10.18632/aging.205112  0.29
2011 Cummins NW, Klicpera A, Sainski AM, Bren GD, Khosla S, Westendorf JJ, Badley AD. Human immunodeficiency virus envelope protein Gp120 induces proliferation but not apoptosis in osteoblasts at physiologic concentrations. Plos One. 6: e24876. PMID 21931863 DOI: 10.1371/journal.pone.0024876  0.289
2016 Carpio LR, Bradley EW, Westendorf JJ. Histone Deacetylase 3 Suppresses Erk Phosphorylation and Matrix Metalloproteinase (Mmp)-13 Activity in Chondrocytes. Connective Tissue Research. PMID 27662443 DOI: 10.1080/03008207.2016.1236088  0.288
2016 Lin Y, Lewallen EA, Camilleri ET, Bonin CA, Jones DL, Dudakovic A, Galeano-Garces C, Wang W, Karperien MJ, Larson AN, Dahm DL, Stuart MJ, Levy BA, Smith J, Ryssman DB, ... Westendorf JJ, et al. RNA-seq analysis of clinical-grade osteochondral allografts reveals activation of early response genes. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 26909883 DOI: 10.1002/jor.23209  0.286
2015 Ryan ZC, Craig TA, McGee-Lawrence M, Westendorf JJ, Kumar R. Alterations in vitamin D metabolite, parathyroid hormone and fibroblast growth factor-23 concentrations in sclerostin-deficient mice permit the maintenance of a high bone mass. The Journal of Steroid Biochemistry and Molecular Biology. 148: 225-31. PMID 25446885 DOI: 10.1016/J.Jsbmb.2014.11.021  0.284
2003 Koka S, Neudauer CL, Li X, Lewis RE, McCarthy JB, Westendorf JJ. The formin-homology-domain-containing protein FHOD1 enhances cell migration. Journal of Cell Science. 116: 1745-55. PMID 12665555 DOI: 10.1242/Jcs.00386  0.284
2016 Bradley EW, Carpio LR, McGee-Lawrence ME, Castillejo Becerra C, Amanatullah DF, Ta LE, Otero M, Goldring MB, Kakar S, Westendorf JJ. Phlpp1 facilitates post-traumatic osteoarthritis and is induced by inflammation and promoter demethylation in human osteoarthritis Osteoarthritis and Cartilage. 24: 1021-1028. DOI: 10.1016/j.joca.2015.12.014  0.28
2013 McGee-Lawrence ME, Westendorf JJ. Reply to vorinostat induced bone loss in mice. Bone. 57: 531-2. PMID 23973558 DOI: 10.1016/J.Bone.2013.08.019  0.277
2012 Westendorf JJ, Goldring MB. Non-coding RNAs and posttranscriptional regulation in cartilage and bone Ibms Bonekey. 9. DOI: 10.1038/BONEKEY.2012.65  0.272
2015 Bonin CA, Lewallen EA, Baheti S, Bradley EW, Stuart MJ, Berry DJ, van Wijnen AJ, Westendorf JJ. Identification of differentially methylated regions in new genes associated with knee osteoarthritis. Gene. PMID 26484395 DOI: 10.1016/j.gene.2015.10.037  0.271
2019 Weivoda MM, Ruan M, Hachfeld CM, Pederson L, Howe A, Davey RA, Zajac JD, Kobayashi Y, Williams BO, Westendorf JJ, Khosla S, Oursler MJ. Wnt Signaling Inhibits Osteoclast Differentiation by Activating Canonical and Noncanonical cAMP/PKA Pathways. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 34: 1546-1548. PMID 31415114 DOI: 10.1002/Jbmr.3740  0.27
1998 Lutterbach B, Westendorf JJ, Linggi B, Patten A, Moniwa M, Davie JR, Huynh KD, Bardwell VJ, Lavinsky RM, Rosenfeld MG, Glass C, Seto E, Hiebert SW. ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors. Molecular and Cellular Biology. 18: 7176-84. PMID 9819404 DOI: 10.1128/Mcb.18.12.7176  0.268
2022 Dudakovic A, Jerez S, Deosthale PJ, Denbeigh JM, Paradise CR, Gluscevic M, Zan P, Begun DL, Camilleri ET, Pichurin O, Khani F, Thaler R, Lian JB, Stein GS, Westendorf JJ, et al. MicroRNA-101a enhances trabecular bone accrual in male mice. Scientific Reports. 12: 13361. PMID 35922466 DOI: 10.1038/s41598-022-17579-0  0.267
2013 van Wijnen AJ, van de Peppel J, van Leeuwen JP, Lian JB, Stein GS, Westendorf JJ, Oursler MJ, Im HJ, Taipaleenmäki H, Hesse E, Riester S, Kakar S. MicroRNA functions in osteogenesis and dysfunctions in osteoporosis. Current Osteoporosis Reports. 11: 72-82. PMID 23605904 DOI: 10.1007/S11914-013-0143-6  0.256
2019 Zhang C, Smith MP, Zhou GK, Lai A, Hoy RC, Mroz V, Torre OM, Laudier DM, Bradley EW, Westendorf JJ, Iatridis JC, Illien-Jünger S. Phlpp1 is associated with human intervertebral disc degeneration and its deficiency promotes healing after needle puncture injury in mice. Cell Death & Disease. 10: 754. PMID 31582730 DOI: 10.1038/S41419-019-1985-3  0.256
2013 Ryan ZC, Ketha H, McNulty MS, McGee-Lawrence M, Craig TA, Grande JP, Westendorf JJ, Singh RJ, Kumar R. Sclerostin alters serum vitamin D metabolite and fibroblast growth factor 23 concentrations and the urinary excretion of calcium. Proceedings of the National Academy of Sciences of the United States of America. 110: 6199-204. PMID 23530237 DOI: 10.1073/Pnas.1221255110  0.249
2016 Carter JM, Wang X, Dong J, Westendorf J, Chou MM, Oliveira AM. USP6 genetic rearrangements in cellular fibroma of tendon sheath. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 27125357 DOI: 10.1038/Modpathol.2016.83  0.248
2015 McGee-Lawrence ME, White TA, LeBrasseur NK, Westendorf JJ. Conditional deletion of Hdac3 in osteoprogenitor cells attenuates diet-induced systemic metabolic dysfunction. Molecular and Cellular Endocrinology. 410: 42-51. PMID 25666992 DOI: 10.1016/J.Mce.2015.02.001  0.248
2000 Lutterbach B, Westendorf JJ, Linggi B, Isaac S, Seto E, Hiebert SW. A mechanism of repression by acute myeloid leukemia-1, the target of multiple chromosomal translocations in acute leukemia Journal of Biological Chemistry. 275: 651-656. PMID 10617663 DOI: 10.1074/Jbc.275.1.651  0.247
2001 Westendorf JJ. The formin/diaphanous-related protein, FHOS, interacts with Rac1 and activates transcription from the serum response element. The Journal of Biological Chemistry. 276: 46453-9. PMID 11590143 DOI: 10.1074/jbc.M105162200  0.241
2008 Westendorf JJ. Osteoporosis. Methods in Molecular Biology (Clifton, N.J.). 455: v-vi. PMID 18488274  0.238
1998 Westendorf JJ, Yamamoto CM, Lenny N, Downing JR, Selsted ME, Hiebert SW. The t(8;21) fusion product, AML-1-ETO, associates with C/EBP-α, inhibits C/EBP-α-dependent transcription, and blocks granulocytic differentiation Molecular and Cellular Biology. 18: 322-333. PMID 9418879 DOI: 10.1128/Mcb.18.1.322  0.238
2005 Koka S, Minick GT, Zhou Y, Westendorf JJ, Boehm MB. Src regulates the activity of the mammalian formin protein FHOD1. Biochemical and Biophysical Research Communications. 336: 1285-91. PMID 16169515 DOI: 10.1016/j.bbrc.2005.08.257  0.23
2014 Wang X, Bledsoe KL, Graham RP, Asmann YW, Viswanatha DS, Lewis JE, Lewis JT, Chou MM, Yaszemski MJ, Jen J, Westendorf JJ, Oliveira AM. Recurrent PAX3-MAML3 fusion in biphenotypic sinonasal sarcoma. Nature Genetics. 46: 666-8. PMID 24859338 DOI: 10.1038/Ng.2989  0.224
2015 Ryan ZC, Craig TA, Filoteo AG, Westendorf JJ, Cartwright EJ, Neyses L, Strehler EE, Kumar R. Deletion of the intestinal plasma membrane calcium pump, isoform 1, Atp2b1, in mice is associated with decreased bone mineral density and impaired responsiveness to 1, 25-dihydroxyvitamin D3. Biochemical and Biophysical Research Communications. 467: 152-6. PMID 26392310 DOI: 10.1016/j.bbrc.2015.09.087  0.22
1999 Fenrick R, Amann JM, Lutterbach B, Wang L, Westendorf JJ, Downing JR, Hiebert SW. Both TEL and AML-1 contribute repression domains to the t(12;21) fusion protein Molecular and Cellular Biology. 19: 6566-6574. PMID 10490596 DOI: 10.1128/Mcb.19.10.6566  0.22
2016 Fang D, Gan H, Lee JH, Han J, Wang Z, Riester SM, Jin L, Chen J, Zhou H, Wang J, Zhang H, Yang N, Bradley EW, Ho TH, Rubin BP, ... ... Westendorf JJ, et al. The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas. Science (New York, N.Y.). PMID 27229140 DOI: 10.1126/Science.Aae0065  0.217
2018 Yan Y, An J, Yang Y, Wu D, Bai Y, Cao W, Ma L, Chen J, Yu Z, He Y, Jin X, Pan Y, Ma T, Wang S, Hou X, ... ... Westendorf JJ, et al. Dual inhibition of AKT-mTOR and AR signaling by targeting HDAC3 in- or-mutated prostate cancer. Embo Molecular Medicine. PMID 29523594 DOI: 10.15252/emmm.201708478  0.213
2011 Undale A, Fraser D, Hefferan T, Kopher RA, Herrick J, Evans GL, Li X, Kakar S, Hayes M, Atkinson E, Yaszemski MJ, Kaufman DS, Westendorf JJ, Khosla S. Induction of fracture repair by mesenchymal cells derived from human embryonic stem cells or bone marrow. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 29: 1804-11. PMID 21674605 DOI: 10.1002/Jor.21480  0.211
2015 van Wijnen AJ, Westendorf JJ. Osteoporosis and osteoarthritis. Preface. Methods in Molecular Biology (Clifton, N.J.). 1226: v. PMID 25493310  0.209
2016 Guo R, Wang X, Chou MM, Yan A, Wenger DE, Al-Ibraheemi A, Molavi DW, Aboulafia A, Jin L, Fritchie K, Oliveira JL, Jenkins RB, Westendorf JJ, Dong J, Oliveira AM. PPP6R3-USP6 Amplification: Novel Oncogenic Mechanism in Malignant Nodular Fasciitis. Genes, Chromosomes & Cancer. PMID 27113271 DOI: 10.1002/Gcc.22366  0.205
2013 McGee-Lawrence ME, Bradley EW, Dudakovic A, Carlson SW, Ryan ZC, Kumar R, Dadsetan M, Yaszemski MJ, Chen Q, An KN, Westendorf JJ. Corrigendum to "Histone deacetylase 3 is required for maintenance of bone mass during aging" [Bone 52 (2013) 296-307] Bone. 53: 320. DOI: 10.1016/J.Bone.2012.12.005  0.204
2016 Carpio LR, Westendorf JJ. Histone Deacetylases in Cartilage Homeostasis and Osteoarthritis. Current Rheumatology Reports. 18: 52. PMID 27402109 DOI: 10.1007/s11926-016-0602-z  0.203
1995 Westendorf JJ, Ahmann GJ, Lust JA, Tschumper RC, Greipp PR, Katzmann JA, Jelinek DF. Molecular and biological role of CD40 in multiple myeloma. Current Topics in Microbiology and Immunology. 194: 63-72. PMID 7534674 DOI: 10.1007/978-3-642-79275-5_9  0.201
2015 Bradley E, Carpio L, Amanatullah D, Kakar S, Ta L, McGee-Lawrence M, Newton A, Westendorf J. Phlpp1 deletion increases Fgf18 expression and protects against surgically-induced osteoarthritis Osteoarthritis and Cartilage. 23: A38-A39. DOI: 10.1016/J.Joca.2015.02.090  0.2
1999 Westendorf JJ, Mernaugh R, Hiebert SW. Identification and characterization of a protein containing formin homology (FH1/FH2) domains Gene. 232: 173-182. PMID 10352228 DOI: 10.1016/S0378-1119(99)00127-4  0.191
2020 Blackburn PR, Carter JM, Oglesbee D, Westendorf JJ, Neff BA, Stichel D, Tsen DW, Gavrilova RH, Wesseling P, von Deimling A, Caulfield TR, Klee EW, Pusch S, Inwards CY. An activating germline variant associated with a tumor entity characterized by unilateral and bilateral chondrosarcoma of the mastoid. Hgg Advances. 1: 100006. PMID 35047830 DOI: 10.1016/j.xhgg.2020.100006  0.187
2013 Deyle DR, Westendorf JJ. WNT1 for the skeleton Ibms Bonekey. 10. DOI: 10.1038/BONEKEY.2013.177  0.18
2021 Rai MF, Wu CL, Capellini TD, Guilak F, Dicks AR, Muthuirulan P, Grandi F, Bhutani N, Westendorf JJ. Single Cell Omics for Musculoskeletal Research. Current Osteoporosis Reports. PMID 33559841 DOI: 10.1007/s11914-021-00662-2  0.172
2016 Fritchie KJ, Jin L, Wang X, Graham RP, Torbenson MS, Lewis JE, Rivera M, Garcia JJ, Schembri-Wismayer DJ, Westendorf JJ, Chou MM, Dong J, Oliveira AM. Fusion Gene Profile of Biphenotypic Sinonasal Sarcoma: An Analysis of 44 Cases. Histopathology. PMID 27454570 DOI: 10.1111/His.13045  0.166
2016 Lewallen EA, Bonin CA, Li X, Smith J, Karperien M, Larson AN, Lewallen DG, Cool SM, Westendorf JJ, Krych AJ, Leontovich AA, Im HJ, van Wijnen AJ. The synovial microenvironment of osteoarthritic joints alters RNA-seq expression profiles of human primary articular chondrocytes. Gene. PMID 27378743 DOI: 10.1016/J.Gene.2016.06.063  0.164
2004 Westendorf JJ, Koka S. Identification of FHOD1-binding proteins and mechanisms of FHOD1-regulated actin dynamics. Journal of Cellular Biochemistry. 92: 29-41. PMID 15095401 DOI: 10.1002/jcb.20031  0.161
2017 Hwang SM, Feigenson M, Begun DL, Shull LC, Culley KL, Otero M, Goldring MB, Ta LE, Kakar S, Bradley EW, Westendorf JJ. Phlpp inhibitors block pain and cartilage degradation associated with osteoarthritis. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 29068480 DOI: 10.1002/jor.23781  0.161
2016 Xu M, Bradley EW, Weivoda MM, Hwang SM, Pirtskhalava T, Decklever T, Curran GL, Ogrodnik M, Jurk D, Johnson KO, Lowe V, Tchkonia T, Westendorf JJ, Kirkland JL. Transplanted Senescent Cells Induce an Osteoarthritis-Like Condition in Mice. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 27516624 DOI: 10.1093/Gerona/Glw154  0.16
2023 Arnold KM, Sicard D, Tschumperlin DJ, Westendorf JJ. Atomic Force Microscopy Micro-Indentation Methods for Determining the Elastic Modulus of Murine Articular Cartilage. Sensors (Basel, Switzerland). 23. PMID 36850434 DOI: 10.3390/s23041835  0.156
2007 Westendorf JJ. Histone deacetylases in control of skeletogenesis. Journal of Cellular Biochemistry. 102: 332-40. PMID 17661352 DOI: 10.1002/jcb.21486  0.148
2015 Lewallen EA, Riester SM, Bonin CA, Kremers HM, Dudakovic A, Kakar S, Cohen RC, Westendorf JJ, Lewallen DG, van Wijnen AJ. Biological strategies for improved osseointegration and osteoinduction of porous metal orthopedic implants. Tissue Engineering. Part B, Reviews. 21: 218-30. PMID 25348836 DOI: 10.1089/ten.TEB.2014.0333  0.14
1997 Jelinek DF, Aagaard-Tillery KM, Arendt BK, Arora T, Tschumper RC, Westendorf JJ. Differential human multiple myeloma cell line responsiveness to interferon-alpha. Analysis of transcription factor activation and interleukin 6 receptor expression. The Journal of Clinical Investigation. 99: 447-56. PMID 9022078 DOI: 10.1172/Jci119179  0.137
2015 Wagner ER, Bravo D, Dadsetan M, Riester SM, Chase S, Westendorf JJ, Dietz AB, van Wijnen AJ, Yaszemski MJ, Kakar S. Ligament Tissue Engineering Using a Novel Porous Polycaprolactone Fumarate Scaffold and Adipose Tissue-Derived Mesenchymal Stem Cells Grown in Platelet Lysate. Tissue Engineering. Part A. 21: 2703-13. PMID 26413793 DOI: 10.1089/Ten.Tea.2015.0183  0.13
2015 Oursler MJ, Westendorf JJ, Weivoda MM, Ruan M, Hachfeld CM, Howe A, Davey R, Zajac J, Williams BO, Khosla S. Response to Wnt Signaling Pathways. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 2135-6. PMID 26309234 DOI: 10.1002/Jbmr.2694  0.123
2020 Kiel DP, Kemp JP, Rivadeneira F, Westendorf JJ, Karasik D, Duncan E, Imai Y, Müller R, Flannick J, Bonewald L, Burtt N. The Musculoskeletal Knowledge Portal: Making Omics Data Useful to the Broader Scientific Community. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 32777102 DOI: 10.1002/Jbmr.4147  0.123
2024 Arnold KM, Weaver SR, Zars EL, Tschumperlin DJ, Westendorf JJ. Inhibition of Phlpp1 preserves the mechanical integrity of articular cartilage in a murine model of post-traumatic osteoarthritis. Osteoarthritis and Cartilage. PMID 38432607 DOI: 10.1016/j.joca.2024.01.008  0.12
2021 Torres HM, Rodezno-Antunes T, VanCleave A, Cao Y, Callahan DL, Westendorf JJ, Tao J. Precise detection of a murine germline mutation of the gene associated with kyphosis and developmental disorders. Journal of Advanced Veterinary and Animal Research. 8: 7-13. PMID 33860007 DOI: 10.5455/javar.2021.h479  0.109
2010 Lewis JL, Krawczak DA, Oegema TR, Westendorf JJ. Effect of decorin and dermatan sulfate on the mechanical properties of a neocartilage. Connective Tissue Research. 51: 159-70. PMID 20001848 DOI: 10.3109/03008200903174342  0.106
2005 Boehm MB, Milius TJ, Zhou Y, Westendorf JJ, Koka S. The mammalian formin FHOD1 interacts with the ERK MAP kinase pathway. Biochemical and Biophysical Research Communications. 335: 1090-4. PMID 16112087 DOI: 10.1016/j.bbrc.2005.07.191  0.067
2022 Rivadeneira F, Loder RT, McGuire AC, Chitwood JR, Duffy K, Civitelli R, Kacena MA, Westendorf JJ. Gender and Geographic Origin as Determinants of Manuscript Publication Outcomes: JBMR® Bibliometric Analysis from 2017 to 2019. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 36063372 DOI: 10.1002/jbmr.4696  0.058
2023 Lundine JP, Huling JD, Adelson PD, Burd RS, Fuentes M, Haarbauer-Krupa J, Hagen K, Iske C, Koterba C, Kurowski BG, Petrucci S, Rose SC, Sadowsky CL, Westendorf J, Truelove A, et al. Using Billing Codes to Create a Pediatric Functional Status e-Score for Children Receiving Inpatient Rehabilitation. Archives of Physical Medicine and Rehabilitation. PMID 37075966 DOI: 10.1016/j.apmr.2023.03.025  0.049
2018 Bradley E, Taylor E, Becerra CC, Lorang I, Burhow S, Reid J, Westendorf J. Inhibitors of Phlpp phosphatases are highly stable and suppress pain following joint injury Osteoarthritis and Cartilage. 26: S356-S357. DOI: 10.1016/j.joca.2018.02.707  0.044
2023 Ung CY, Correia C, Li H, Adams CM, Westendorf JJ, Zhu S. Multiorgan locked-state model of chronic diseases and systems pharmacology opportunities. Drug Discovery Today. 29: 103825. PMID 37967790 DOI: 10.1016/j.drudis.2023.103825  0.036
2021 Westendorf JJ, Bonewald LF, Kiel DP, Burtt NP. The Musculoskeletal Knowledge Portal: improving access to multi-omics data. Nature Reviews. Rheumatology. PMID 34686856 DOI: 10.1038/s41584-021-00711-1  0.024
2018 Civitelli R, Westendorf J, Hofbauer L, Rivadeneira F. Focusing on the Science: JBMR Manuscript Types. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 29989665 DOI: 10.1002/Jbmr.3545  0.023
2020 Rivadeneira F, Westendorf JJ. Bringing Genomic Discoveries to the Clinic: Integrating Omic Data Into the Musculoskeletal Field Through International Teamwork and Collaboration. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 35: 1623-1625. PMID 32845524 DOI: 10.1002/jbmr.4148  0.021
2020 Alliston T, Foucher KC, Frederick B, Hernandez CJ, Iatridis JC, Kozloff KM, Lewis KJ, Liu XS, Mercer DM, Ochia R, Queen RM, Rimnac CM, van der Meulen MCH, Westendorf JJ. The Importance of Diversity, Equity and Inclusion in Orthopaedic Research. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 32267012 DOI: 10.1002/Jor.24685  0.018
2020 Hofbauer LC, Rivadeneira F, Westendorf JJ, Civitelli R. Scientific Editing in the COVID-19 Era-Personal Vignettes from the JBMR Editors. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 32413197 DOI: 10.1002/Jbmr.4050  0.01
2007 Westendorf JJ. Utilizing the Perioperative Nursing Data Set in a surgical setting. Plastic Surgical Nursing : Official Journal of the American Society of Plastic and Reconstructive Surgical Nurses. 27: 181-4. PMID 18165723 DOI: 10.1097/01.PSN.0000306181.50071.39  0.01
2007 Westendorf JJ. Magnet recognition program. Plastic Surgical Nursing : Official Journal of the American Society of Plastic and Reconstructive Surgical Nurses. 27: 102-4. PMID 17565306 DOI: 10.1097/01.PSN.0000278241.00533.ea  0.01
2007 Westendorf JJ. The nursing shortage: recruitment and retention of current and future nurses. Plastic Surgical Nursing : Official Journal of the American Society of Plastic and Reconstructive Surgical Nurses. 27: 93-7. PMID 17565304 DOI: 10.1097/01.PSN.0000278239.10835.1c  0.01
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