Sergio Grinstein - Publications

University of Toronto, Toronto, ON, Canada 
Cell Biology, Biochemistry

188 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Levin R, Grinstein S, Canton J. The life cycle of phagosomes: formation, maturation, and resolution. Immunological Reviews. 273: 156-79. PMID 27558334 DOI: 10.1111/imr.12439  0.8
2016 Howard JC, Florentinus-Mefailoski A, Bowden P, Trimble W, Grinstein S, Marshall JG. OxLDL receptor chromatography from live human U937 cells identifies SYK(L) that regulates phagocytosis of oxLDL. Analytical Biochemistry. PMID 27510553 DOI: 10.1016/j.ab.2016.07.021  0.8
2016 Schlam D, Canton J, Carreño M, Kopinski H, Freeman SA, Grinstein S, Fairn GD. Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5-Trisphosphate Homeostasis. Mbio. 7. PMID 27048806 DOI: 10.1128/mBio.02242-15  0.8
2016 Wong HS, Jaumouillé V, Freeman SA, Doodnauth SA, Schlam D, Canton J, Mukovozov IM, Saric A, Grinstein S, Robinson LA. Chemokine Signaling Enhances CD36 Responsiveness toward Oxidized Low-Density Lipoproteins and Accelerates Foam Cell Formation. Cell Reports. PMID 26997267 DOI: 10.1016/j.celrep.2016.02.071  0.8
2016 Vance DT, Dufresne J, Florentinus-Mefailoski A, Tucholska M, Trimble W, Grinstein S, Marshall JG. A phagocytosis assay for oxLDL versus IgG coated microbeads in human U937 macrophages. Analytical Biochemistry. PMID 26800863 DOI: 10.1016/j.ab.2016.01.007  0.8
2016 Freeman SA, Goyette J, Furuya W, Woods EC, Bertozzi CR, Bergmeier W, Hinz B, van der Merwe PA, Das R, Grinstein S. Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis. Cell. 164: 128-140. PMID 26771488 DOI: 10.1016/j.cell.2015.11.048  0.8
2015 Schlam D, Bagshaw RD, Freeman SA, Collins RF, Pawson T, Fairn GD, Grinstein S. Phosphoinositide 3-kinase enables phagocytosis of large particles by terminating actin assembly through Rac/Cdc42 GTPase-activating proteins. Nature Communications. 6: 8623. PMID 26465210 DOI: 10.1038/ncomms9623  0.8
2015 D'Costa VM, Braun V, Landekic M, Shi R, Proteau A, McDonald L, Cygler M, Grinstein S, Brumell JH. Salmonella Disrupts Host Endocytic Trafficking by SopD2-Mediated Inhibition of Rab7. Cell Reports. 12: 1508-18. PMID 26299973 DOI: 10.1016/j.celrep.2015.07.063  0.8
2015 Freeman SA, Jaumouillé V, Choi K, Hsu BE, Wong HS, Abraham L, Graves ML, Coombs D, Roskelley CD, Das R, Grinstein S, Gold MR. Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor. Nature Communications. 6: 6168. PMID 25644899 DOI: 10.1038/ncomms7168  0.8
2015 Levin R, Grinstein S, Schlam D. Phosphoinositides in phagocytosis and macropinocytosis. Biochimica Et Biophysica Acta. 1851: 805-823. PMID 25238964 DOI: 10.1016/j.bbalip.2014.09.005  0.8
2014 Freeman SA, Grinstein S. Phagocytosis: receptors, signal integration, and the cytoskeleton. Immunological Reviews. 262: 193-215. PMID 25319336 DOI: 10.1111/imr.12212  0.8
2014 Wong HS, Jaumouillé V, Heit B, Doodnauth SA, Patel S, Huang YW, Grinstein S, Robinson LA. Cytoskeletal confinement of CX3CL1 limits its susceptibility to proteolytic cleavage by ADAM10. Molecular Biology of the Cell. 25: 3884-99. PMID 25253723 DOI: 10.1091/mbc.E13-11-0633  0.8
2014 Jaumouillé V, Farkash Y, Jaqaman K, Das R, Lowell CA, Grinstein S. Actin cytoskeleton reorganization by syk regulates fcγ receptor responsiveness by increasing its lateral mobility and clustering Developmental Cell. 29: 534-546. PMID 24914558 DOI: 10.1016/j.devcel.2014.04.031  0.8
2014 Dodd DA, Worth RG, Rosen MK, Grinstein S, van Oers NS, Hansen EJ. The Haemophilus ducreyi LspA1 protein inhibits phagocytosis by using a new mechanism involving activation of C-terminal Src kinase. Mbio. 5: e01178-14. PMID 24902122 DOI: 10.1128/mBio.01178-14  0.8
2014 Flannagan RS, Canton J, Furuya W, Glogauer M, Grinstein S. The phosphatidylserine receptor TIM4 utilizes integrins as coreceptors to effect phagocytosis. Molecular Biology of the Cell. 25: 1511-22. PMID 24623723 DOI: 10.1091/mbc.E13-04-0212  0.48
2013 Neculai D, Schwake M, Ravichandran M, Zunke F, Collins RF, Peters J, Neculai M, Plumb J, Loppnau P, Pizarro JC, Seitova A, Trimble WS, Saftig P, Grinstein S, Dhe-Paganon S. Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36. Nature. 504: 172-6. PMID 24162852 DOI: 10.1038/nature12684  0.8
2013 Roppenser B, Kwon H, Canadien V, Xu R, Devreotes PN, Grinstein S, Brumell JH. Multiple host kinases contribute to Akt activation during Salmonella infection. Plos One. 8: e71015. PMID 23990921 DOI: 10.1371/journal.pone.0071015  0.8
2013 Mukherjee D, Sen A, Boettner DR, Fairn GD, Schlam D, Bonilla Valentin FJ, Michael McCaffery J, Hazbun T, Staiger CJ, Grinstein S, Lemmon SK, Claudio Aguilar R. Bem3, a Cdc42 GTPase-activating protein, traffics to an intracellular compartment and recruits the secretory Rab GTPase Sec4 to endomembranes. Journal of Cell Science. 126: 4560-71. PMID 23943876 DOI: 10.1242/jcs.117663  0.8
2013 Strijbis K, Tafesse FG, Fairn GD, Witte MD, Dougan SK, Watson N, Spooner E, Esteban A, Vyas VK, Fink GR, Grinstein S, Ploegh HL. Bruton's Tyrosine Kinase (BTK) and Vav1 contribute to Dectin1-dependent phagocytosis of Candida albicans in macrophages. Plos Pathogens. 9: e1003446. PMID 23825946 DOI: 10.1371/journal.ppat.1003446  0.8
2013 Bohdanowicz M, Schlam D, Hermansson M, Rizzuti D, Fairn GD, Ueyama T, Somerharju P, Du G, Grinstein S. Phosphatidic acid is required for the constitutive ruffling and macropinocytosis of phagocytes. Molecular Biology of the Cell. 24: 1700-12, S1-7. PMID 23576545 DOI: 10.1091/mbc.E12-11-0789  0.8
2013 Hayashi H, Tamura A, Krishnan D, Tsukita S, Suzuki Y, Kocinsky HS, Aronson PS, Orlowski J, Grinstein S, Alexander RT. Ezrin is required for the functional regulation of the epithelial sodium proton exchanger, NHE3. Plos One. 8: e55623. PMID 23405179 DOI: 10.1371/journal.pone.0055623  0.8
2013 Heit B, Kim H, Cosío G, Castaño D, Collins R, Lowell CA, Kain KC, Trimble WS, Grinstein S. Multimolecular signaling complexes enable Syk-mediated signaling of CD36 internalization. Developmental Cell. 24: 372-83. PMID 23395392 DOI: 10.1016/j.devcel.2013.01.007  0.8
2012 Nordenfelt P, Grinstein S, Björck L, Tapper H. V-ATPase-mediated phagosomal acidification is impaired by Streptococcus pyogenes through Mga-regulated surface proteins. Microbes and Infection / Institut Pasteur. 14: 1319-29. PMID 22981599 DOI: 10.1016/j.micinf.2012.08.005  0.48
2012 Jaqaman K, Grinstein S. Regulation from within: The cytoskeleton in transmembrane signaling Trends in Cell Biology. 22: 515-526. PMID 22917551 DOI: 10.1016/j.tcb.2012.07.006  0.8
2012 Coen K, Flannagan RS, Baron S, Carraro-Lacroix LR, Wang D, Vermeire W, Michiels C, Munck S, Baert V, Sugita S, Wuytack F, Hiesinger PR, Grinstein S, Annaert W. Lysosomal calcium homeostasis defects, not proton pump defects, cause endo-lysosomal dysfunction in PSEN-deficient cells. The Journal of Cell Biology. 198: 23-35. PMID 22753898 DOI: 10.1083/jcb.201201076  0.8
2012 Sarantis H, Balkin DM, De Camilli P, Isberg RR, Brumell JH, Grinstein S. Yersinia entry into host cells requires Rab5-dependent dephosphorylation of PI(4,5)Pâ‚‚ and membrane scission. Cell Host & Microbe. 11: 117-28. PMID 22341461 DOI: 10.1016/j.chom.2012.01.010  0.8
2012 Roppenser B, Grinstein S, Brumell JH. Modulation of host phosphoinositide metabolism during Salmonella invasion by the type III secreted effector SopB. Methods in Cell Biology. 108: 173-86. PMID 22325603 DOI: 10.1016/B978-0-12-386487-1.00009-2  0.8
2012 Bohdanowicz M, Balkin DM, De Camilli P, Grinstein S. Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling. Molecular Biology of the Cell. 23: 176-87. PMID 22072788 DOI: 10.1091/mbc.E11-06-0489  0.8
2012 Flannagan RS, Jaumouillé V, Huynh KK, Plumb JD, Downey GP, Valvano MA, Grinstein S. Burkholderia cenocepacia disrupts host cell actin cytoskeleton by inactivating Rac and Cdc42. Cellular Microbiology. 14: 239-54. PMID 22023324 DOI: 10.1111/j.1462-5822.2011.01715.x  0.8
2011 Orlowski J, Grinstein S. Na+/H+ exchangers. Comprehensive Physiology. 1: 2083-100. PMID 23733698 DOI: 10.1002/cphy.c110020  0.8
2011 Lam GY, Fattouh R, Muise AM, Grinstein S, Higgins DE, Brumell JH. Listeriolysin O suppresses phospholipase C-mediated activation of the microbicidal NADPH oxidase to promote Listeria monocytogenes infection. Cell Host & Microbe. 10: 627-34. PMID 22177565 DOI: 10.1016/j.chom.2011.11.005  0.8
2011 Fairn GD, Hermansson M, Somerharju P, Grinstein S. Phosphatidylserine is polarized and required for proper Cdc42 localization and for development of cell polarity. Nature Cell Biology. 13: 1424-30. PMID 21964439 DOI: 10.1038/ncb2351  0.8
2011 Jaqaman K, Kuwata H, Touret N, Collins R, Trimble WS, Danuser G, Grinstein S. Cytoskeletal control of CD36 diffusion promotes its receptor and signaling function. Cell. 146: 593-606. PMID 21854984 DOI: 10.1016/j.cell.2011.06.049  0.8
2011 Kaniuk NA, Canadien V, Bagshaw RD, Bakowski M, Braun V, Landekic M, Mitra S, Huang J, Heo WD, Meyer T, Pelletier L, Andrews-Polymenis H, McClelland M, Pawson T, Grinstein S, et al. Salmonella exploits Arl8B-directed kinesin activity to promote endosome tubulation and cell-to-cell transfer. Cellular Microbiology. 13: 1812-23. PMID 21824248 DOI: 10.1111/j.1462-5822.2011.01663.x  0.8
2011 Golebiewska U, Kay JG, Masters T, Grinstein S, Im W, Pastor RW, Scarlata S, McLaughlin S. Evidence for a fence that impedes the diffusion of phosphatidylinositol 4,5-bisphosphate out of the forming phagosomes of macrophages. Molecular Biology of the Cell. 22: 3498-507. PMID 21795401 DOI: 10.1091/mbc.E11-02-0114  0.8
2011 Botelho RJ, Grinstein S. Phagocytosis. Current Biology : Cb. 21: R533-8. PMID 21783028 DOI: 10.1016/j.cub.2011.05.053  1
2011 Maures TJ, Su HW, Argetsinger LS, Grinstein S, Carter-Su C. Phosphorylation controls a dual-function polybasic nuclear localization sequence in the adapter protein SH2B1β to regulate its cellular function and distribution. Journal of Cell Science. 124: 1542-52. PMID 21486950 DOI: 10.1242/jcs.078949  0.8
2011 Alexander RT, Jaumouillé V, Yeung T, Furuya W, Peltekova I, Boucher A, Zasloff M, Orlowski J, Grinstein S. Membrane surface charge dictates the structure and function of the epithelial Na+/H+ exchanger. The Embo Journal. 30: 679-91. PMID 21245831 DOI: 10.1038/emboj.2010.356  0.8
2010 Flannagan RS, Harrison RE, Yip CM, Jaqaman K, Grinstein S. Dynamic macrophage "probing" is required for the efficient capture of phagocytic targets Journal of Cell Biology. 191: 1205-1218. PMID 21135140 DOI: 10.1083/jcb.201007056  0.8
2010 Bohdanowicz M, Cosío G, Backer JM, Grinstein S. Class I and class III phosphoinositide 3-kinases are required for actin polymerization that propels phagosomes. The Journal of Cell Biology. 191: 999-1012. PMID 21115805 DOI: 10.1083/jcb.201004005  0.8
2010 Huynh KK, Plumb JD, Downey GP, Valvano MA, Grinstein S. Inactivation of macrophage Rab7 by Burkholderia cenocepacia. Journal of Innate Immunity. 2: 522-33. PMID 20829607 DOI: 10.1159/000319864  0.8
2010 Steinberg BE, Huynh KK, Brodovitch A, Jabs S, Stauber T, Jentsch TJ, Grinstein S. A cation counterflux supports lysosomal acidification. The Journal of Cell Biology. 189: 1171-86. PMID 20566682 DOI: 10.1083/jcb.200911083  0.8
2010 Bakowski MA, Braun V, Lam GY, Yeung T, Heo WD, Meyer T, Finlay BB, Grinstein S, Brumell JH. The phosphoinositide phosphatase SopB manipulates membrane surface charge and trafficking of the Salmonella-containing vacuole. Cell Host & Microbe. 7: 453-62. PMID 20542249 DOI: 10.1016/j.chom.2010.05.011  0.8
2010 Braun V, Wong A, Landekic M, Hong WJ, Grinstein S, Brumell JH. Sorting nexin 3 (SNX3) is a component of a tubular endosomal network induced by Salmonella and involved in maturation of the Salmonella-containing vacuole. Cellular Microbiology. 12: 1352-67. PMID 20482551 DOI: 10.1111/j.1462-5822.2010.01476.x  0.8
2010 Lee HK, Mattei LM, Steinberg BE, Alberts P, Lee YH, Chervonsky A, Mizushima N, Grinstein S, Iwasaki A. In vivo requirement for Atg5 in antigen presentation by dendritic cells. Immunity. 32: 227-39. PMID 20171125 DOI: 10.1016/j.immuni.2009.12.006  0.8
2010 Koivusalo M, Welch C, Hayashi H, Scott CC, Kim M, Alexander T, Touret N, Hahn KM, Grinstein S. Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling. The Journal of Cell Biology. 188: 547-63. PMID 20156964 DOI: 10.1083/jcb.200908086  0.8
2010 Lee JS, Lee YM, Kim JY, Park HW, Grinstein S, Orlowski J, Kim E, Kim KH, Lee MG. BetaPix up-regulates Na+/H+ exchanger 3 through a Shank2-mediated protein-protein interaction. The Journal of Biological Chemistry. 285: 8104-13. PMID 20080968 DOI: 10.1074/jbc.M109.055079  0.8
2010 Casey JR, Grinstein S, Orlowski J. Sensors and regulators of intracellular pH. Nature Reviews. Molecular Cell Biology. 11: 50-61. PMID 19997129 DOI: 10.1038/nrm2820  0.8
2009 Fairn GD, Ogata K, Botelho RJ, Stahl PD, Anderson RA, De Camilli P, Meyer T, Wodak S, Grinstein S. An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis. The Journal of Cell Biology. 187: 701-14. PMID 19951917 DOI: 10.1083/jcb.200909025  0.8
2009 Erdman LK, Cosio G, Helmers AJ, Gowda DC, Grinstein S, Kain KC. CD36 and TLR interactions in inflammation and phagocytosis: implications for malaria. Journal of Immunology (Baltimore, Md. : 1950). 183: 6452-9. PMID 19864601 DOI: 10.4049/jimmunol.0901374  0.8
2009 Collins RF, Touret N, Kuwata H, Tandon NN, Grinstein S, Trimble WS. Uptake of oxidized low density lipoprotein by CD36 occurs by an actin-dependent pathway distinct from macropinocytosis. The Journal of Biological Chemistry. 284: 30288-97. PMID 19740737 DOI: 10.1074/jbc.M109.045104  0.8
2009 Botelho RJ, Harrison RE, Stone JC, Hancock JF, Philips MR, Jongstra-Bilen J, Mason D, Plumb J, Gold MR, Grinstein S. Localized diacylglycerol-dependent stimulation of Ras and Rap1 during phagocytosis. The Journal of Biological Chemistry. 284: 28522-32. PMID 19700408 DOI: 10.1074/jbc.M109.009514  0.8
2009 Alexander RT, Grinstein S. Tethering, recycling and activation of the epithelial sodium-proton exchanger, NHE3. The Journal of Experimental Biology. 212: 1630-7. PMID 19448073 DOI: 10.1242/jeb.027375  0.8
2009 Huang J, Canadien V, Lam GY, Steinberg BE, Dinauer MC, Magalhaes MA, Glogauer M, Grinstein S, Brumell JH. Activation of antibacterial autophagy by NADPH oxidases. Proceedings of the National Academy of Sciences of the United States of America. 106: 6226-31. PMID 19339495 DOI: 10.1073/pnas.0811045106  0.8
2009 Wang Y, Roche O, Yan MS, Finak G, Evans AJ, Metcalf JL, Hast BE, Hanna SC, Wondergem B, Furge KA, Irwin MS, Kim WY, Teh BT, Grinstein S, Park M, et al. Regulation of endocytosis via the oxygen-sensing pathway. Nature Medicine. 15: 319-24. PMID 19252501 DOI: 10.1038/nm.1922  0.8
2009 Sason H, Milgrom M, Weiss AM, Melamed-Book N, Balla T, Grinstein S, Backert S, Rosenshine I, Aroeti B. Enteropathogenic Escherichia coli subverts phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate upon epithelial cell infection. Molecular Biology of the Cell. 20: 544-55. PMID 18987340 DOI: 10.1091/mbc.E08-05-0516  0.8
2008 Mallo GV, Espina M, Smith AC, Terebiznik MR, Alemán A, Finlay BB, Rameh LE, Grinstein S, Brumell JH. SopB promotes phosphatidylinositol 3-phosphate formation on Salmonella vacuoles by recruiting Rab5 and Vps34. The Journal of Cell Biology. 182: 741-52. PMID 18725540 DOI: 10.1083/jcb.200804131  0.8
2008 Tian W, Li XJ, Stull ND, Ming W, Sun CI, Bissonnette SA, Yaffe MB, Grinstein S, Atkinson SJ, Dinauer MC. Fc{gamma}R-stimulated activation of the NADPH oxidase: Phosphoinositide- binding protein p40phox regulates NADPH oxidase activity after enzyme assembly on the phagosome Blood. 112: 3867-3877. PMID 18711001 DOI: 10.1182/blood-2007-11-126029  0.8
2008 Jaqaman K, Loerke D, Mettlen M, Kuwata H, Grinstein S, Schmid SL, Danuser G. Robust single-particle tracking in live-cell time-lapse sequences. Nature Methods. 5: 695-702. PMID 18641657 DOI: 10.1038/nmeth.1237  0.8
2008 Huang YW, Yan M, Collins RF, Diciccio JE, Grinstein S, Trimble WS. Mammalian septins are required for phagosome formation. Molecular Biology of the Cell. 19: 1717-26. PMID 18272790 DOI: 10.1091/mbc.E07-07-0641  0.8
2008 Yeung T, Gilbert GE, Shi J, Silvius J, Kapus A, Grinstein S. Membrane phosphatidylserine regulates surface charge and protein localization. Science (New York, N.Y.). 319: 210-3. PMID 18187657 DOI: 10.1126/science.1152066  0.8
2008 Hayashi H, Aharonovitz O, Alexander RT, Touret N, Furuya W, Orlowski J, Grinstein S. Na+/H+ exchange and pH regulation in the control of neutrophil chemokinesis and chemotaxis. American Journal of Physiology. Cell Physiology. 294: C526-34. PMID 18094149 DOI: 10.1152/ajpcell.00219.2007  0.8
2007 Goldenberg NM, Grinstein S, Silverman M. Golgi-bound Rab34 is a novel member of the secretory pathway Molecular Biology of the Cell. 18: 4762-4771. PMID 17881736 DOI: 10.1091/mbc.E06-11-0991  0.8
2007 Orlowski J, Grinstein S. Emerging roles of alkali cation/proton exchangers in organellar homeostasis. Current Opinion in Cell Biology. 19: 483-92. PMID 17646094 DOI: 10.1016/  0.8
2007 Trimble WS, Grinstein S. TB or not TB: calcium regulation in mycobacterial survival. Cell. 130: 12-4. PMID 17632049 DOI: 10.1016/j.cell.2007.06.039  0.8
2007 Steinberg BE, Touret N, Vargas-Caballero M, Grinstein S. In situ measurement of the electrical potential across the phagosomal membrane using FRET and its contribution to the proton-motive force. Proceedings of the National Academy of Sciences of the United States of America. 104: 9523-8. PMID 17517624 DOI: 10.1073/pnas.0700783104  0.8
2007 Lee WL, Mason D, Schreiber AD, Grinstein S. Quantitative analysis of membrane remodeling at the phagocytic cup. Molecular Biology of the Cell. 18: 2883-92. PMID 17507658 DOI: 10.1091/mbc.E06-05-0450  0.8
2007 Binker MG, Cosen-Binker LI, Terebiznik MR, Mallo GV, McCaw SE, Eskelinen EL, Willenborg M, Brumell JH, Saftig P, Grinstein S, Gray-Owen SD. Arrested maturation of Neisseria-containing phagosomes in the absence of the lysosome-associated membrane proteins, LAMP-1 and LAMP-2. Cellular Microbiology. 9: 2153-66. PMID 17506821 DOI: 10.1111/j.1462-5822.2007.00946.x  0.8
2007 Yan M, Di Ciano-Oliveira C, Grinstein S, Trimble WS. Coronin function is required for chemotaxis and phagocytosis in human neutrophils. Journal of Immunology (Baltimore, Md. : 1950). 178: 5769-78. PMID 17442961 DOI: 10.4049/jimmunol.178.9.5769  0.8
2007 Mason D, Mallo GV, Terebiznik MR, Payrastre B, Finlay BB, Brumell JH, Rameh L, Grinstein S. Alteration of epithelial structure and function associated with PtdIns(4,5)P2 degradation by a bacterial phosphatase. The Journal of General Physiology. 129: 267-83. PMID 17389247 DOI: 10.1085/jgp.200609656  0.8
2007 Smith AC, Won DH, Braun V, Jiang X, Macrae C, Casanova JE, Scidmore MA, Grinstein S, Meyer T, Brumell JH. A network of Rab GTPases controls phagosome maturation and is modulated by Salmonella enterica serovar Typhimurium Journal of Cell Biology. 176: 263-268. PMID 17261845 DOI: 10.1083/jcb.200611056  0.8
2007 Huynh KK, Eskelinen EL, Scott CC, Malevanets A, Saftig P, Grinstein S. LAMP proteins are required for fusion of lysosomes with phagosomes Embo Journal. 26: 313-324. PMID 17245426 DOI: 10.1038/sj.emboj.7601511  0.8
2007 Alexander RT, Malevanets A, Durkan AM, Kocinsky HS, Aronson PS, Orlowski J, Grinstein S. Membrane curvature alters the activation kinetics of the epithelial Na+/H+ exchanger, NHE3. The Journal of Biological Chemistry. 282: 7376-84. PMID 17218318 DOI: 10.1074/jbc.M608557200  0.8
2007 Steinberg BE, Scott CC, Grinstein S. High-throughput assays of phagocytosis, phagosome maturation, and bacterial invasion American Journal of Physiology - Cell Physiology. 292. PMID 17020932 DOI: 10.1152/ajpcell.00358.2006  0.8
2007 Lamothe J, Huynh KK, Grinstein S, Valvano MA. Intracellular survival of Burkholderia cenocepacia in macrophages is associated with a delay in the maturation of bacteria-containing vacuoles Cellular Microbiology. 9: 40-53. PMID 16869828 DOI: 10.1111/j.1462-5822.2006.00766.x  0.8
2006 Alexander RT, Grinstein S. Activation of kinases upon volume changes: role in cellular homeostasis. Contributions to Nephrology. 152: 105-24. PMID 17065808 DOI: 10.1159/000096319  0.8
2006 Suh CI, Stull ND, Xing JL, Tian W, Price MO, Grinstein S, Yaffe MB, Atkinson S, Dinauer MC. The phosphoinositide-binding protein p40 phox activates the NADPH oxidase during FcγIIA receptor-induced phagocytosis Journal of Experimental Medicine. 203: 1915-1925. PMID 16880255 DOI: 10.1083/JCB1744OIA8  0.8
2006 Yeung T, Terebiznik M, Yu L, Silvius J, Abidi WM, Philips M, Levine T, Kapus A, Grinstein S. Receptor activation alters inner surface potential during phagocytosis. Science (New York, N.Y.). 313: 347-51. PMID 16857939 DOI: 10.1126/science.1129551  0.8
2006 Corbett-Nelson EF, Mason D, Marshall JG, Collette Y, Grinstein S. Signaling-dependent immobilization of acylated proteins in the inner monolayer of the plasma membrane. The Journal of Cell Biology. 174: 255-65. PMID 16831891 DOI: 10.1083/jcb.200605044  0.8
2006 Alexander RT, Grinstein S. Na+/H+ exchangers and the regulation of volume Acta Physiologica. 187: 159-167. PMID 16734752 DOI: 10.1111/j.1748-1716.2006.01558.x  0.8
2006 Martin-Orozco N, Touret N, Zaharik ML, Park E, Kopelman R, Miller S, Finlay BB, Gros P, Grinstein S. Visualization of vacuolar acidification-induced transcription of genes of pathogens inside macrophages. Molecular Biology of the Cell. 17: 498-510. PMID 16251362 DOI: 10.1091/mbc.E04-12-1096  0.8
2005 Touret N, Paroutis P, Terebiznik M, Harrison RE, Trombetta S, Pypaert M, Chow A, Jiang A, Shaw J, Yip C, Moore HP, van der Wel N, Houben D, Peters PJ, de Chastellier C, ... ... Grinstein S, et al. Quantitative and dynamic assessment of the contribution of the ER to phagosome formation. Cell. 123: 157-70. PMID 16213220 DOI: 10.1016/j.cell.2005.08.018  0.8
2005 Alexander RT, Furuya W, Szászi K, Orlowski J, Grinstein S. Rho GTPases dictate the mobility of the Na/H exchanger NHE3 in epithelia: role in apical retention and targeting. Proceedings of the National Academy of Sciences of the United States of America. 102: 12253-8. PMID 16103375 DOI: 10.1073/pnas.0409197102  0.8
2005 Tse SM, Mason D, Botelho RJ, Chiu B, Reyland M, Hanada K, Inman RD, Grinstein S. Accumulation of diacylglycerol in the Chlamydia inclusion vacuole: possible role in the inhibition of host cell apoptosis. The Journal of Biological Chemistry. 280: 25210-5. PMID 15863503 DOI: 10.1074/jbc.M501980200  1
2005 Yan M, Collins RF, Grinstein S, Trimble WS. Coronin-1 function is required for phagosome formation. Molecular Biology of the Cell. 16: 3077-87. PMID 15829569 DOI: 10.1091/mbc.E04-11-0989  0.8
2005 Scott CC, Dobson W, Botelho RJ, Coady-Osberg N, Chavrier P, Knecht DA, Heath C, Stahl P, Grinstein S. Phosphatidylinositol-4,5-bisphosphate hydrolysis directs actin remodeling during phagocytosis. The Journal of Cell Biology. 169: 139-49. PMID 15809313 DOI: 10.1083/jcb.200412162  0.8
2005 Lee WL, Kim MK, Schreiber AD, Grinstein S. Role of ubiquitin and proteasomes in phagosome maturation. Molecular Biology of the Cell. 16: 2077-90. PMID 15703218 DOI: 10.1091/mbc.E04-06-0464  0.8
2005 Rubin BB, Downey GP, Koh A, Degousee N, Ghomashchi F, Nallan L, Stefanski E, Harkin DW, Sun C, Smart BP, Lindsay TF, Cherepanov V, Vachon E, Kelvin D, Sadilek M, ... ... Grinstein S, et al. Cytosolic phospholipase A2-alpha is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated bacterial killing, and the innate immune response to pulmonary infection: cPLA2-alpha does not regulate neutrophil NADPH oxidase activity. The Journal of Biological Chemistry. 280: 7519-29. PMID 15475363 DOI: 10.1074/jbc.M407438200  0.8
2004 Chow CW, Downey GP, Grinstein S. Measurements of phagocytosis and phagosomal maturation. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 15.7. PMID 18228442 DOI: 10.1002/0471143030.cb1507s22  0.8
2004 Harrison RE, Brumell JH, Khandani A, Bucci C, Scott CC, Jiang X, Finlay BB, Grinstein S. Salmonella impairs RILP recruitment to Rab7 during maturation of invasion vacuoles. Molecular Biology of the Cell. 15: 3146-54. PMID 15121880 DOI: 10.1091/mbc.E04-02-0092  0.8
2004 Vieira OV, Harrison RE, Scott CC, Stenmark H, Alexander D, Liu J, Gruenberg J, Schreiber AD, Grinstein S. Acquisition of Hrs, an essential component of phagosomal maturation, is impaired by mycobacteria. Molecular and Cellular Biology. 24: 4593-604. PMID 15121875 DOI: 10.1128/MCB.24.10.4593-4604.2004  0.8
2004 Hayashi H, Szászi K, Coady-Osberg N, Furuya W, Bretscher AP, Orlowski J, Grinstein S. Inhibition and redistribution of NHE3, the apical Na+/H+ exchanger, by Clostridium difficile toxin B. The Journal of General Physiology. 123: 491-504. PMID 15078917 DOI: 10.1085/jgp.200308979  0.8
2004 Brumell JH, Grinstein S. Salmonella redirects phagosomal maturation. Current Opinion in Microbiology. 7: 78-84. PMID 15036145 DOI: 10.1016/j.mib.2003.12.005  0.8
2004 Botelho RJ, Scott CC, Grinstein S. Phosphoinositide involvement in phagocytosis and phagosome maturation. Current Topics in Microbiology and Immunology. 282: 1-30. PMID 14594212  0.8
2004 Orlowski J, Grinstein S. Diversity of the mammalian sodium/proton exchanger SLC9 gene family. PflüGers Archiv : European Journal of Physiology. 447: 549-65. PMID 12845533 DOI: 10.1007/s00424-003-1110-3  0.8
2003 Scott CC, Botelho RJ, Grinstein S. Phagosome maturation: a few bugs in the system. The Journal of Membrane Biology. 193: 137-52. PMID 12962275 DOI: 10.1007/s00232-002-2008-2  0.8
2003 Harrison RE, Bucci C, Vieira OV, Schroer TA, Grinstein S. Phagosomes fuse with late endosomes and/or lysosomes by extension of membrane protrusions along microtubules: role of Rab7 and RILP. Molecular and Cellular Biology. 23: 6494-506. PMID 12944476 DOI: 10.1128/MCB.23.18.6494-6506.2003  0.8
2003 Gu H, Botelho RJ, Yu M, Grinstein S, Neel BG. Critical role for scaffolding adapter Gab2 in FcγR-mediated phagocytosis Journal of Cell Biology. 161: 1151-1161. PMID 12821647 DOI: 10.1083/jcb.200212158  0.8
2003 Scott CC, Furuya W, Trimble WS, Grinstein S. Activation of store-operated calcium channels: assessment of the role of snare-mediated vesicular transport. The Journal of Biological Chemistry. 278: 30534-9. PMID 12764154 DOI: 10.1074/jbc.M304718200  0.8
2003 Brumell JH, Grinstein S. Role of lipid-mediated signal transduction in bacterial internalization. Cellular Microbiology. 5: 287-97. PMID 12713488 DOI: 10.1046/j.1462-5822.2003.00273.x  0.8
2003 Vieira OV, Bucci C, Harrison RE, Trimble WS, Lanzetti L, Gruenberg J, Schreiber AD, Stahl PD, Grinstein S. Modulation of Rab5 and Rab7 recruitment to phagosomes by phosphatidylinositol 3-kinase. Molecular and Cellular Biology. 23: 2501-14. PMID 12640132 DOI: 10.1128/MCB.23.7.2501-2514.2003  0.8
2003 Dombrosky-Ferlan P, Grishin A, Botelho RJ, Sampson M, Wang L, Rudert WA, Grinstein S, Corey SJ. Felic (CIP4b), a novel binding partner with the Src kinase Lyn and Cdc42, localizes to the phagocytic cup. Blood. 101: 2804-9. PMID 12456510 DOI: 10.1182/blood-2002-03-0851  1
2003 Tse SM, Furuya W, Gold E, Schreiber AD, Sandvig K, Inman RD, Grinstein S. Differential role of actin, clathrin, and dynamin in Fc gamma receptor-mediated endocytosis and phagocytosis. The Journal of Biological Chemistry. 278: 3331-8. PMID 12424246 DOI: 10.1074/jbc.M207966200  0.8
2002 Botelho RJ, Tapper H, Furuya W, Mojdami D, Grinstein S. Fc gamma R-mediated phagocytosis stimulates localized pinocytosis in human neutrophils. Journal of Immunology (Baltimore, Md. : 1950). 169: 4423-9. PMID 12370376 DOI: 10.4049/jimmunol.169.8.4423  1
2002 Terebiznik MR, Vieira OV, Marcus SL, Slade A, Yip CM, Trimble WS, Meyer T, Finlay BB, Grinstein S. Elimination of host cell PtdIns(4,5)P(2) by bacterial SigD promotes membrane fission during invasion by Salmonella. Nature Cell Biology. 4: 766-73. PMID 12360287 DOI: 10.1038/ncb854  0.8
2002 Coppolino MG, Dierckman R, Loijens J, Collins RF, Pouladi M, Jongstra-Bilen J, Schreiber AD, Trimble WS, Anderson R, Grinstein S. Inhibition of phosphatidylinositol-4-phosphate 5-kinase Ialpha impairs localized actin remodeling and suppresses phagocytosis. The Journal of Biological Chemistry. 277: 43849-57. PMID 12223494 DOI: 10.1074/jbc.M209046200  0.8
2002 Collins RF, Schreiber AD, Grinstein S, Trimble WS. Syntaxins 13 and 7 function at distinct steps during phagocytosis. Journal of Immunology (Baltimore, Md. : 1950). 169: 3250-6. PMID 12218144 DOI: 10.4049/jimmunol.169.6.3250  0.8
2002 Szaszi K, Paulsen A, Szabo EZ, Numata M, Grinstein S, Orlowski J. Clathrin-mediated endocytosis and recycling of the neuron-specific Na+/H+ exchanger NHE5 isoform. Regulation by phosphatidylinositol 3'-kinase and the actin cytoskeleton. The Journal of Biological Chemistry. 277: 42623-32. PMID 12205089 DOI: 10.1074/jbc.M206629200  0.8
2002 Canonne-Hergaux F, Calafat J, Richer E, Cellier M, Grinstein S, Borregaard N, Gros P. Expression and subcellular localization of NRAMP1 in human neutrophil granules Blood. 100: 268-275. PMID 12070036 DOI: 10.1182/blood.V100.1.268  0.8
2002 Vieira OV, Botelho RJ, Grinstein S. Phagosome maturation: aging gracefully. The Biochemical Journal. 366: 689-704. PMID 12061891 DOI: 10.1042/BJ20020691  1
2002 Booth JW, Kim MK, Jankowski A, Schreiber AD, Grinstein S. Contrasting requirements for ubiquitylation during Fc receptor-mediated endocytosis and phagocytosis. The Embo Journal. 21: 251-8. PMID 11823418 DOI: 10.1093/emboj/21.3.251  0.8
2002 Scott CC, Cuellar-Mata P, Matsuo T, Davidson HW, Grinstein S. Role of 3-phosphoinositides in the maturation of Salmonella-containing vacuoles within host cells. The Journal of Biological Chemistry. 277: 12770-6. PMID 11821391 DOI: 10.1074/jbc.M110399200  0.8
2002 Hayashi H, Szászi K, Coady-Osberg N, Orlowski J, Kinsella JL, Grinstein S. A slow pH-dependent conformational transition underlies a novel mode of activation of the epithelial Na+/H+ exchanger-3 isoform. The Journal of Biological Chemistry. 277: 11090-6. PMID 11792708 DOI: 10.1074/jbc.M111868200  0.8
2002 Jankowski A, Scott CC, Grinstein S. Determinants of the phagosomal pH in neutrophils Journal of Biological Chemistry. 277: 6059-6066. PMID 11744729 DOI: 10.1074/jbc.M110059200  0.8
2001 Booth JW, Trimble WS, Grinstein S. Membrane dynamics in phagocytosis Seminars in Immunology. 13: 357-364. PMID 11708891 DOI: 10.1006/smim.2001.0332  0.8
2001 Jankowski A, Kim JH, Collins RF, Daneman R, Walton P, Grinstein S. In situ measurements of the pH of mammalian peroxisomes using the fluorescent protein pHluorin. The Journal of Biological Chemistry. 276: 48748-53. PMID 11641408 DOI: 10.1074/jbc.M109003200  0.8
2001 Vieira OV, Botelho RJ, Rameh L, Brachmann SM, Matsuo T, Davidson HW, Schreiber A, Backer JM, Cantley LC, Grinstein S. Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation. The Journal of Cell Biology. 155: 19-25. PMID 11581283 DOI: 10.1083/jcb.200107069  1
2001 Szászi K, Kurashima K, Kaibuchi K, Grinstein S, Orlowski J. Role of the cytoskeleton in mediating cAMP-dependent protein kinase inhibition of the epithelial Na+/H+ exchanger NHE3. The Journal of Biological Chemistry. 276: 40761-8. PMID 11522794 DOI: 10.1074/jbc.M106724200  0.8
2001 Marshall JG, Booth JW, Stambolic V, Mak T, Balla T, Schreiber AD, Meyer T, Grinstein S. Restricted accumulation of phosphatidylinositol 3-kinase products in a plasmalemmal subdomain during Fcγ receptor-mediated phagocytosis Journal of Cell Biology. 153: 1369-1380. PMID 11425868 DOI: 10.1083/jcb.153.7.1369  0.8
2001 Aharonovitz O, Kapus A, Szászi K, Coady-Osberg N, Jancelewicz T, Orlowski J, Grinstein S. Modulation of Na+/H+ exchange activity by Cl- American Journal of Physiology - Cell Physiology. 281. PMID 11401835 DOI: 10.1152/ajpcell.2001.281.1.C133  0.8
2001 Hackam DJ, Botelho RJ, Sjolin C, Rotstein OD, Robinson JM, Schreiber AD, Grinstein S. Indirect role for COPI in the completion of FCgamma receptor-mediated phagocytosis. The Journal of Biological Chemistry. 276: 18200-8. PMID 11279223 DOI: 10.1074/jbc.M102009200  0.8
2001 Coppolino MG, Kong C, Mohtashami M, Schreiber AD, Brumell JH, Finlay BB, Grinstein S, Trimble WS. Requirement for N-ethylmaleimide-sensitive factor activity at different stages of bacterial invasion and phagocytosis. The Journal of Biological Chemistry. 276: 4772-80. PMID 11092884 DOI: 10.1074/jbc.M007792200  0.8
2000 Botelho RJ, Teruel M, Dierckman R, Anderson R, Wells A, York JD, Meyer T, Grinstein S. Localized biphasic changes in phosphatidylinositol-4,5-bisphosphate at sites of phagocytosis. The Journal of Cell Biology. 151: 1353-68. PMID 11134066 DOI: 10.1083/jcb.151.7.1353  1
2000 Szászi K, Grinstein S, Orlowski J, Kapus A. Regulation of the epithelial Na+/H+ exchanger isoform by the cytoskeleton Cellular Physiology and Biochemistry. 10: 265-272. PMID 11125205 DOI: 10.1159/000016358  0.8
2000 Kruger J, Butler JR, Cherapanov V, Dong Q, Ginzberg H, Govindarajan A, Grinstein S, Siminovitch KA, Downey GP. Deficiency of Src homology 2-containing phosphatase 1 results in abnormalities in murine neutrophil function: studies in motheaten mice. Journal of Immunology (Baltimore, Md. : 1950). 165: 5847-59. PMID 11067945 DOI: 10.4049/jimmunol.165.10.5847  0.8
2000 Aharonovitz O, Zaun HC, Balla T, York JD, Orlowski J, Grinstein S. Intracellular pH regulation by Na(+)/H(+) exchange requires phosphatidylinositol 4,5-bisphosphate. The Journal of Cell Biology. 150: 213-24. PMID 10893269 DOI: 10.1083/jcb.150.1.213  0.8
2000 Szászi K, Kurashima K, Kapus A, Paulsen A, Kaibuchi K, Grinstein S, Orlowski J. RhoA and rho kinase regulate the epithelial Na+/H+ exchanger NHE3. Role of myosin light chain phosphorylation. The Journal of Biological Chemistry. 275: 28599-606. PMID 10893221 DOI: 10.1074/jbc.M001193200  0.8
2000 Bajno L, Peng XR, Schreiber AD, Moore HP, Trimble WS, Grinstein S. Focal exocytosis of VAMP3-containing vesicles at sites of phagosome formation. The Journal of Cell Biology. 149: 697-706. PMID 10791982 DOI: 10.1083/jcb.149.3.697  0.8
2000 Botelho RJ, Hackam DJ, Schreiber AD, Grinstein S. Role of COPI in phagosome maturation. The Journal of Biological Chemistry. 275: 15717-27. PMID 10748188 DOI: 10.1074/jbc.M910068199  0.8
2000 Schapiro FB, Grinstein S. Determinants of the pH of the Golgi complex. The Journal of Biological Chemistry. 275: 21025-32. PMID 10748071 DOI: 10.1074/jbc.M002386200  1
1999 Chow CW, Khurana S, Woodside M, Grinstein S, Orlowski J. The epithelial Na(+)/H(+) exchanger, NHE3, is internalized through a clathrin-mediated pathway. The Journal of Biological Chemistry. 274: 37551-8. PMID 10608808 DOI: 10.1074/jbc.274.53.37551  0.8
1999 Zhang J, Kong C, Xie H, McPherson PS, Grinstein S, Trimble WS. Phosphatidylinositol polyphosphate binding to the mammalian septin H5 is modulated by GTP. Current Biology : Cb. 9: 1458-67. PMID 10607590 DOI: 10.1016/S0960-9822(00)80115-3  0.8
1999 Plant PJ, Manolson MF, Grinstein S, Demaurex N. Alternative mechanisms of vacuolar acidification in H+-ATPase-deficient yeast Journal of Biological Chemistry. 274: 37270-37279. PMID 10601292 DOI: 10.1074/jbc.274.52.37270  0.8
1999 Yusta B, Somwar R, Wang F, Munroe D, Grinstein S, Klip A, Drucker DJ. Identification of glucagon-like peptide-2 (GLP-2)-activated signaling pathways in baby hamster kidney fibroblasts expressing the rat GLP-2 receptor. The Journal of Biological Chemistry. 274: 30459-67. PMID 10521425 DOI: 10.1074/jbc.274.43.30459  0.8
1999 Kurashia K, D'Souza S, Szászi K, Ramjeesingh R, Orlowski J, Grinstein S. The apical Na+/H+ exchanger isoform NHE3 is regulated by the actin cytoskeleton Journal of Biological Chemistry. 274: 29843-29849. PMID 10514464 DOI: 10.1074/jbc.274.42.29843  0.8
1999 Downey GP, Botelho RJ, Butler JR, Moltyaner Y, Chien P, Schreiber AD, Grinstein S. Phagosomal maturation, acidification, and inhibition of bacterial growth in nonphagocytic cells transfected with FcgammaRIIA receptors. The Journal of Biological Chemistry. 274: 28436-44. PMID 10497205 DOI: 10.1074/jbc.274.40.28436  0.8
1999 Wieczorek H, Brown D, Grinstein S, Ehrenfeld J, Harvey WR. Animal plasma membrane energization by proton-motive V-ATPases. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 21: 637-48. PMID 10440860 DOI: 10.1002/(SICI)1521-1878(199908)21:8<637::AID-BIES3>3.0.CO;2-W  0.8
1999 Wiemann M, Schwark JR, Bonnet U, Jansen HW, Grinstein S, Baker RE, Lang HJ, Wirth K, Bingmann D. Selective inhibition of the Na+/H+ exchanger type 3 activates CO2/H+-sensitive medullary neurones Pflugers Archiv European Journal of Physiology. 438: 255-262. PMID 10398853 DOI: 10.1007/s004240050907  0.8
1999 Chow CW, Woodside M, Demaurex N, Yu FH, Plant P, Rotin D, Grinstein S, Orlowski J. Proline-rich motifs of the Na+/H+ exchanger 2 isoform. Binding of Src homology domain 3 and role in apical targeting in epithelia. The Journal of Biological Chemistry. 274: 10481-8. PMID 10187839 DOI: 10.1074/jbc.274.15.10481  0.8
1999 Gruenheid S, Canonne-Hergaux F, Gauthier S, Hackam DJ, Grinstein S, Gros P. The iron transport protein NRAMP2 is an integral membrane glycoprotein that colocalizes with transferrin in recycling endosomes. The Journal of Experimental Medicine. 189: 831-41. PMID 10049947 DOI: 10.1084/jem.189.5.831  0.8
1999 Petrecca K, Atanasiu R, Grinstein S, Orlowski J, Shrier A. Subcellular localization of the Na+/H+ exchanger NHE1 in rat myocardium. The American Journal of Physiology. 276: H709-17. PMID 9950874 DOI: 10.1152/ajpheart.1999.276.2.H709  0.8
1999 Hackam DJ, Rotstein OD, Grinstein S. Phagosomal acidification mechanisms and functional significance Advances in Cellular and Molecular Biology of Membranes and Organelles. 5: 299-319. DOI: 10.1016/S1874-5172(99)80037-6  0.8
1998 Hackam DJ, Rotstein OD, Sjolin C, Schreiber AD, Trimble WS, Grinstein S. v-SNARE-dependent secretion is required for phagocytosis. Proceedings of the National Academy of Sciences of the United States of America. 95: 11691-6. PMID 9751727 DOI: 10.1073/pnas.95.20.11691  0.8
1998 Kurashima K, Szabó EZ, Lukacs G, Orlowski J, Grinstein S. Endosomal recycling of the Na+/H+ exchanger NHE3 isoform is regulated by the phosphatidylinositol 3-kinase pathway. The Journal of Biological Chemistry. 273: 20828-36. PMID 9694828 DOI: 10.1074/jbc.273.33.20828  0.8
1998 Shrode LD, Gan BS, D'Souza SJA, Orlowski J, Grinstein S. Topological analysis of NHE1, the ubiquitous Na+/H+ exchanger using chymotryptic cleavage American Journal of Physiology - Cell Physiology. 275. PMID 9688597 DOI: 10.1152/ajpcell.1998.275.2.C431  0.8
1998 Hackam DJ, Rotstein OD, Zhang W, Gruenheid S, Gros P, Grinstein S. Host resistance to intracellular infection: mutation of natural resistance-associated macrophage protein 1 (Nramp1) impairs phagosomal acidification. The Journal of Experimental Medicine. 188: 351-64. PMID 9670047 DOI: 10.1084/jem.188.2.351  0.8
1998 Hall RA, Premont RT, Chow CW, Blitzer JT, Pitcher JA, Claing A, Stoffel RH, Barak LS, Shenolikar S, Weinman EJ, Grinstein S, Lefkowitz RJ. The beta2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange. Nature. 392: 626-30. PMID 9560162 DOI: 10.1038/33458  0.8
1998 Kim JH, Johannes L, Goud B, Antony C, Lingwood CA, Daneman R, Grinstein S. Noninvasive measurement of the pH of the endoplasmic reticulum at rest and during calcium release. Proceedings of the National Academy of Sciences of the United States of America. 95: 2997-3002. PMID 9501204 DOI: 10.1073/pnas.95.6.2997  0.8
1998 Schapiro FB, Lingwood C, Furuya W, Grinstein S. pH-independent retrograde targeting of glycolipids to the Golgi complex. The American Journal of Physiology. 274: C319-32. PMID 9486120  0.8
1998 Demaurex N, Furuya W, D'Souza S, Bonifacino JS, Grinstein S. Mechanism of acidification of the trans-Golgi network (TGN): In situ measurements of pH using retrieval of TGN38 and furin from the cell surface Journal of Biological Chemistry. 273: 2044-2051. PMID 9442042 DOI: 10.1074/jbc.273.4.2044  0.8
1997 Hackam DJ, Rotstein OD, Zhang WJ, Demaurex N, Woodside M, Tsai O, Grinstein S. Regulation of phagosomal acidification. Differential targeting of Na +/H + exchangers, Na +/K +-ATPases, and vacuolar-type H +-ATPases Journal of Biological Chemistry. 272: 29810-29820. PMID 9368053 DOI: 10.1074/jbc.272.47.29810  0.8
1997 Tong J, Oyamada H, Demaurex N, Grinstein S, McCarthy TV, MacLennan DH. Caffeine and halothane sensitivity of intracellular Ca2+ release is altered by 15 calcium release channel (ryanodine receptor) mutations associated with malignant hyperthermia and/or central core disease. The Journal of Biological Chemistry. 272: 26332-9. PMID 9334205 DOI: 10.1074/jbc.272.42.26332  0.8
1997 Shrode LD, Rubie EA, Woodgett JR, Grinstein S. Cytosolic alkalinization increases stress-activated protein kinase/c- Jun NH2-terminal kinase (SAPK/JNK) activity and p38 mitogen-activated protein kinase activity by a calcium-independent mechanism Journal of Biological Chemistry. 272: 13653-13659. PMID 9153215 DOI: 10.1074/jbc.272.21.13653  0.8
1997 Krump E, Sanghera JS, Pelech SL, Furuya W, Grinstein S. Chemotactic peptide N-formyl-met-leu-phe activation of p38 mitogen-activated protein kinase (MAPK) and MAPK-activated protein kinase-2 in human neutrophils. The Journal of Biological Chemistry. 272: 937-44. PMID 8995385 DOI: 10.1074/jbc.272.2.937  0.8
1997 Brumell JH, Chan CK, Butler J, Borregaard N, Siminovitch KA, Grinstein S, Downey GP. Regulation of Src homology 2-containing tyrosine phosphatase 1 during activation of human neutrophils: Role of protein kinase C Journal of Biological Chemistry. 272: 875-882. PMID 8995376 DOI: 10.1074/jbc.272.2.875  0.8
1997 Robertson MA, Woodside M, Foskett JK, Orlowski J, Grinstein S. Muscarinic agonists induce phosphorylation-independent activation of the NHE-1 isoform of the Na+/H+ antiporter in salivary acinar cells. The Journal of Biological Chemistry. 272: 287-94. PMID 8995260 DOI: 10.1074/jbc.272.1.287  0.8
1996 Kim JH, Lingwood CA, Williams DB, Furuya W, Manolson MF, Grinstein S. Dynamic measurement of the pH of the Golgi complex in living cells using retrograde transport of the verotoxin receptor Journal of Cell Biology. 134: 1387-1399. PMID 8830769  0.8
1996 Hackam DJ, Grinstein S, Rotstein OD. Intracellular pH regulation in leukocytes: Mechanisms and functional significance Shock. 5: 17-21. PMID 8821098  0.8
1996 Nanda A, Brumell JH, Nordström T, Kjeldsen L, Sengeløv H, Borregaard N, Rotstem OD, Grinstein S. Activation of proton pumping in human neutrophils occurs by exocytosis of vesicles bearing vacuolar-type H+-ATPases Journal of Biological Chemistry. 271: 15963-15970. PMID 8663143 DOI: 10.1074/jbc.271.27.15963  0.8
1996 Brumell JH, Burkhardt AL, Bolen JB, Grinstein S. Endogenous reactive oxygen intermediates activate tyrosine kinases in human neutrophils Journal of Biological Chemistry. 271: 1455-1461. PMID 8576138 DOI: 10.1074/jbc.271.3.1455  0.8
1996 Brisseau GF, Grinstein S, Hackam DJ, Nordström T, Manolson MF, Khine AA, Rotstein OD. Interleukin-1 increases vacuolar-type H +-ATPase activity in murine peritoneal macrophages Journal of Biological Chemistry. 271: 2005-2011. PMID 8567651 DOI: 10.1074/jbc.271.4.2005  0.8
1995 Chow CW, Demaurex N, Grinstein S. Ion transport and the function of phagocytic cells. Current Opinion in Hematology. 2: 89-95. PMID 9371976 DOI: 10.1097/00062752-199502010-00012  0.8
1994 Qu AY, Nanda A, Curnutte JT, Grinstein S. Development of a H+-selective conductance during granulocytic differentiation of HL-60 cells American Journal of Physiology - Cell Physiology. 266. PMID 8203491 DOI: 10.1152/ajpcell.1994.266.5.C1263  0.8
1993 Kapus A, Romanek R, Qu AY, Rotstein OD, Grinstein S. A pH-sensitive and voltage-dependent proton conductance in the plasma membrane of macrophages Journal of General Physiology. 102: 729-760. PMID 8270911 DOI: 10.1085/jgp.102.4.729  0.8
1991 Trudel S, Pâquet MR, Grinstein S. Mechanism of vanadate-induced activation of tyrosine phosphorylation and of the respiratory burst in HL60 cells. Role of reduced oxygen metabolites. The Biochemical Journal. 276: 611-9. PMID 1712198 DOI: 10.1042/bj2760611  0.8
1990 Grinstein S, Foskett JK. Ionic mechanisms of cell volume regulation in leukocytes Annual Review of Physiology. 52: 399-414. PMID 2184762  0.8
1990 Downey GP, Chan CK, Trudel S, Grinstein S. Actin assembly in electropermeabilized neutrophils: Role of intracellular calcium Journal of Cell Biology. 110: 1975-1982. PMID 2112547 DOI: 10.1083/jcb.110.6.1975  0.8
1990 Trudel S, Downey GP, Grinstein S, Pâquet MR. Activation of permeabilized HL60 cells by vanadate. Evidence for divergent signalling pathways. The Biochemical Journal. 269: 127-31. PMID 1695841 DOI: 10.1042/bj2690127  0.8
1989 Rotin D, Grinstein S. Impaired cell volume regulation in Na+-H+ exchange-deficient mutants American Journal of Physiology - Cell Physiology. 257. PMID 2558570 DOI: 10.1152/ajpcell.1989.257.6.C1158  0.8
1989 Grinstein S, Rotin D, Mason MJ. Na+/H+ exchange and growth factor-induced cytosolic pH changes. Role in cellular proliferation Bba - Reviews On Biomembranes. 988: 73-97. PMID 2535787 DOI: 10.1016/0304-4157(89)90004-X  0.8
1987 Jakubovicz DE, Grinstein S, Klip A. Cell swelling following recovery from acidification in C6 glioma cells: an in vitro model of postischemic brain edema Brain Research. 435: 138-146. PMID 3427448 DOI: 10.1016/0006-8993(87)91594-0  0.8
1987 van der Meulen J, Klip A, Grinstein S. POSSIBLE MECHANISM FOR CEREBRAL OEDEMA IN DIABETIC KETOACIDOSIS The Lancet. 330: 306-308. PMID 2886767 DOI: 10.1016/S0140-6736(87)90892-0  0.8
1986 Klip A, Mack E, Cragoe EJ, Grinstein S. Regulation of amino acid uptake by phorbol esters and hypertonic solutions in rat thymocytes Journal of Cellular Physiology. 127: 244-252. PMID 3009498  0.8
1985 Deber CM, Tom-Kun J, Mack E, Grinstein S. Bromo-A23187: A nonfluorescent calcium ionophore for use with fluorescent probes Analytical Biochemistry. 146: 349-352. PMID 3927770 DOI: 10.1016/0003-2697(85)90550-0  0.8
1984 Grinstein S, Elder B, Clarke CA, Buchwald M. Is cytoplasmic Ca2+ in lymphocytes elevated in cystic fibrosis Bba - Biomembranes. 769: 270-274. PMID 6691977 DOI: 10.1016/0005-2736(84)90032-4  0.8
1983 Rink TJ, Sanchez A, Grinstein S, Rothstein A. Volume restoration in osmotically swollen lymphocytes does not involve changes in free Ca2+ concentration Bba - Molecular Cell Research. 762: 593-596. PMID 6871254 DOI: 10.1016/0167-4889(83)90064-2  0.8
1983 Grinstein S, Clarke CA, Rothstein A. Activation of Na+/H+ exchange in lymphocytes by osmotically induced volume changes and by cytoplasmic acidification Journal of General Physiology. 82: 619-638. PMID 6644271 DOI: 10.1085/jgp.82.5.619  0.8
1983 Grinstein S, Clarke CA, Rothstein A, Gelfand EW. Volume-induced anion conductance in human B lymphocytes is cation independent The American Journal of Physiology. 245. PMID 6191575 DOI: 10.1152/ajpcell.1983.245.1.C160  0.8
1982 Grinstein S, Clarke CA, Dupre A, Rothstein A. Volume-induced increase of anion permeability in human lymphocytes Journal of General Physiology. 80: 801-823. PMID 7175489 DOI: 10.1085/jgp.80.6.801  0.8
1982 Grinstein S, Clarke CA, Rothstein A. Increased anion permeability during volume regulation in human lymphocytes Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 299: 509-518. PMID 6130543 DOI: 10.1098/rstb.1982.0148  0.8
1980 Rothstein A, Ramjeesingh M, Grinstein S, Knauf PA. Protein structure in relation to anion transport in red cells. Annals of the New York Academy of Sciences. 341: 433-43. PMID 6994547 DOI: 10.1111/j.1749-6632.1980.tb47188.x  0.8
1980 Klip A, Grinstein S, Semenza G. The small-intestinal sodium, D-glucose cotransporter is inserted in the brush border membrane asymmetrically Annals of the New York Academy of Sciences. 358: 374-377. PMID 6938160  0.8
1980 Klip A, Grinstein S, Biber J, Semenza G. Interaction of the sugar carrier of intestinal brush-border membranes with HgCl2 Bba - Biomembranes. 598: 100-114. PMID 6448071 DOI: 10.1016/0005-2736(80)90268-0  0.8
1979 Klip A, Grinstein S, Semenza G. Partial purification of the sugar carrier of intestinal brush border membranes. Enrichment of the phlorizin-binding component by selective extractions The Journal of Membrane Biology. 51: 47-73. PMID 522129 DOI: 10.1007/BF01869343  0.8
1979 Klip A, Grinstein S, Semenza G. Distribution of sulfhydryl groups in intestinal brush border membranes. Localization of side-chains essential for glucose transport and phlorizin binding Bba - Biomembranes. 558: 233-245. PMID 508745 DOI: 10.1016/0005-2736(79)90063-4  0.8
1979 Klip A, Grinstein S, Semenza G. Transmembrane disposition of the phlorizin binding protein of intestinal brush borders Febs Letters. 99: 91-96. PMID 437137 DOI: 10.1016/0014-5793(79)80256-2  0.8
1979 Klip A, Grinstein S, Marti T, Semenza G. Transient opening of brush border membrane vesicles in alkaline media. Preservation of D-glucose transport after removal of extrinsic proteins Febs Letters. 105: 224-228. PMID 39782 DOI: 10.1016/0014-5793(79)80616-X  0.8
1978 Rothstein A, Grinstein S, Ship S, Knauf PA. Asymmetry of functional sites of the erythrocyte anion transport protein Trends in Biochemical Sciences. 3: 126-128. DOI: 10.1016/S0968-0004(78)80030-9  0.8
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