Sergio Grinstein - Publications

University of Toronto, Toronto, ON, Canada 
Cell Biology, Biochemistry

74/156 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Levin R, Grinstein S, Canton J. The life cycle of phagosomes: formation, maturation, and resolution. Immunological Reviews. 273: 156-79. PMID 27558334 DOI: 10.1111/imr.12439  0.8
2016 Howard JC, Florentinus-Mefailoski A, Bowden P, Trimble W, Grinstein S, Marshall JG. OxLDL receptor chromatography from live human U937 cells identifies SYK(L) that regulates phagocytosis of oxLDL. Analytical Biochemistry. PMID 27510553 DOI: 10.1016/j.ab.2016.07.021  0.8
2016 Schlam D, Canton J, Carreño M, Kopinski H, Freeman SA, Grinstein S, Fairn GD. Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5-Trisphosphate Homeostasis. Mbio. 7. PMID 27048806 DOI: 10.1128/mBio.02242-15  0.8
2016 Wong HS, Jaumouillé V, Freeman SA, Doodnauth SA, Schlam D, Canton J, Mukovozov IM, Saric A, Grinstein S, Robinson LA. Chemokine Signaling Enhances CD36 Responsiveness toward Oxidized Low-Density Lipoproteins and Accelerates Foam Cell Formation. Cell Reports. PMID 26997267 DOI: 10.1016/j.celrep.2016.02.071  0.8
2016 Vance DT, Dufresne J, Florentinus-Mefailoski A, Tucholska M, Trimble W, Grinstein S, Marshall JG. A phagocytosis assay for oxLDL versus IgG coated microbeads in human U937 macrophages. Analytical Biochemistry. PMID 26800863 DOI: 10.1016/j.ab.2016.01.007  0.8
2016 Freeman SA, Goyette J, Furuya W, Woods EC, Bertozzi CR, Bergmeier W, Hinz B, van der Merwe PA, Das R, Grinstein S. Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis. Cell. 164: 128-140. PMID 26771488 DOI: 10.1016/j.cell.2015.11.048  0.8
2015 Schlam D, Bagshaw RD, Freeman SA, Collins RF, Pawson T, Fairn GD, Grinstein S. Phosphoinositide 3-kinase enables phagocytosis of large particles by terminating actin assembly through Rac/Cdc42 GTPase-activating proteins. Nature Communications. 6: 8623. PMID 26465210 DOI: 10.1038/ncomms9623  0.8
2015 D'Costa VM, Braun V, Landekic M, Shi R, Proteau A, McDonald L, Cygler M, Grinstein S, Brumell JH. Salmonella Disrupts Host Endocytic Trafficking by SopD2-Mediated Inhibition of Rab7. Cell Reports. 12: 1508-18. PMID 26299973 DOI: 10.1016/j.celrep.2015.07.063  0.8
2015 Freeman SA, Jaumouillé V, Choi K, Hsu BE, Wong HS, Abraham L, Graves ML, Coombs D, Roskelley CD, Das R, Grinstein S, Gold MR. Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor. Nature Communications. 6: 6168. PMID 25644899 DOI: 10.1038/ncomms7168  0.8
2015 Levin R, Grinstein S, Schlam D. Phosphoinositides in phagocytosis and macropinocytosis. Biochimica Et Biophysica Acta. 1851: 805-823. PMID 25238964 DOI: 10.1016/j.bbalip.2014.09.005  0.8
2014 Freeman SA, Grinstein S. Phagocytosis: receptors, signal integration, and the cytoskeleton. Immunological Reviews. 262: 193-215. PMID 25319336 DOI: 10.1111/imr.12212  0.8
2014 Wong HS, Jaumouillé V, Heit B, Doodnauth SA, Patel S, Huang YW, Grinstein S, Robinson LA. Cytoskeletal confinement of CX3CL1 limits its susceptibility to proteolytic cleavage by ADAM10. Molecular Biology of the Cell. 25: 3884-99. PMID 25253723 DOI: 10.1091/mbc.E13-11-0633  0.8
2014 Jaumouillé V, Farkash Y, Jaqaman K, Das R, Lowell CA, Grinstein S. Actin cytoskeleton reorganization by syk regulates fcγ receptor responsiveness by increasing its lateral mobility and clustering Developmental Cell. 29: 534-546. PMID 24914558 DOI: 10.1016/j.devcel.2014.04.031  0.8
2014 Dodd DA, Worth RG, Rosen MK, Grinstein S, van Oers NS, Hansen EJ. The Haemophilus ducreyi LspA1 protein inhibits phagocytosis by using a new mechanism involving activation of C-terminal Src kinase. Mbio. 5: e01178-14. PMID 24902122 DOI: 10.1128/mBio.01178-14  0.8
2014 Flannagan RS, Canton J, Furuya W, Glogauer M, Grinstein S. The phosphatidylserine receptor TIM4 utilizes integrins as coreceptors to effect phagocytosis. Molecular Biology of the Cell. 25: 1511-22. PMID 24623723 DOI: 10.1091/mbc.E13-04-0212  0.48
2013 Neculai D, Schwake M, Ravichandran M, Zunke F, Collins RF, Peters J, Neculai M, Plumb J, Loppnau P, Pizarro JC, Seitova A, Trimble WS, Saftig P, Grinstein S, Dhe-Paganon S. Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36. Nature. 504: 172-6. PMID 24162852 DOI: 10.1038/nature12684  0.8
2013 Roppenser B, Kwon H, Canadien V, Xu R, Devreotes PN, Grinstein S, Brumell JH. Multiple host kinases contribute to Akt activation during Salmonella infection. Plos One. 8: e71015. PMID 23990921 DOI: 10.1371/journal.pone.0071015  0.8
2013 Mukherjee D, Sen A, Boettner DR, Fairn GD, Schlam D, Bonilla Valentin FJ, Michael McCaffery J, Hazbun T, Staiger CJ, Grinstein S, Lemmon SK, Claudio Aguilar R. Bem3, a Cdc42 GTPase-activating protein, traffics to an intracellular compartment and recruits the secretory Rab GTPase Sec4 to endomembranes. Journal of Cell Science. 126: 4560-71. PMID 23943876 DOI: 10.1242/jcs.117663  0.8
2013 Strijbis K, Tafesse FG, Fairn GD, Witte MD, Dougan SK, Watson N, Spooner E, Esteban A, Vyas VK, Fink GR, Grinstein S, Ploegh HL. Bruton's Tyrosine Kinase (BTK) and Vav1 contribute to Dectin1-dependent phagocytosis of Candida albicans in macrophages. Plos Pathogens. 9: e1003446. PMID 23825946 DOI: 10.1371/journal.ppat.1003446  0.8
2013 Bohdanowicz M, Schlam D, Hermansson M, Rizzuti D, Fairn GD, Ueyama T, Somerharju P, Du G, Grinstein S. Phosphatidic acid is required for the constitutive ruffling and macropinocytosis of phagocytes. Molecular Biology of the Cell. 24: 1700-12, S1-7. PMID 23576545 DOI: 10.1091/mbc.E12-11-0789  0.8
2013 Hayashi H, Tamura A, Krishnan D, Tsukita S, Suzuki Y, Kocinsky HS, Aronson PS, Orlowski J, Grinstein S, Alexander RT. Ezrin is required for the functional regulation of the epithelial sodium proton exchanger, NHE3. Plos One. 8: e55623. PMID 23405179 DOI: 10.1371/journal.pone.0055623  0.8
2013 Heit B, Kim H, Cosío G, Castaño D, Collins R, Lowell CA, Kain KC, Trimble WS, Grinstein S. Multimolecular signaling complexes enable Syk-mediated signaling of CD36 internalization. Developmental Cell. 24: 372-83. PMID 23395392 DOI: 10.1016/j.devcel.2013.01.007  0.8
2012 Nordenfelt P, Grinstein S, Björck L, Tapper H. V-ATPase-mediated phagosomal acidification is impaired by Streptococcus pyogenes through Mga-regulated surface proteins. Microbes and Infection / Institut Pasteur. 14: 1319-29. PMID 22981599 DOI: 10.1016/j.micinf.2012.08.005  0.48
2012 Jaqaman K, Grinstein S. Regulation from within: The cytoskeleton in transmembrane signaling Trends in Cell Biology. 22: 515-526. PMID 22917551 DOI: 10.1016/j.tcb.2012.07.006  0.8
2012 Coen K, Flannagan RS, Baron S, Carraro-Lacroix LR, Wang D, Vermeire W, Michiels C, Munck S, Baert V, Sugita S, Wuytack F, Hiesinger PR, Grinstein S, Annaert W. Lysosomal calcium homeostasis defects, not proton pump defects, cause endo-lysosomal dysfunction in PSEN-deficient cells. The Journal of Cell Biology. 198: 23-35. PMID 22753898 DOI: 10.1083/jcb.201201076  0.8
2012 Sarantis H, Balkin DM, De Camilli P, Isberg RR, Brumell JH, Grinstein S. Yersinia entry into host cells requires Rab5-dependent dephosphorylation of PI(4,5)Pâ‚‚ and membrane scission. Cell Host & Microbe. 11: 117-28. PMID 22341461 DOI: 10.1016/j.chom.2012.01.010  0.8
2012 Roppenser B, Grinstein S, Brumell JH. Modulation of host phosphoinositide metabolism during Salmonella invasion by the type III secreted effector SopB. Methods in Cell Biology. 108: 173-86. PMID 22325603 DOI: 10.1016/B978-0-12-386487-1.00009-2  0.8
2012 Bohdanowicz M, Balkin DM, De Camilli P, Grinstein S. Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling. Molecular Biology of the Cell. 23: 176-87. PMID 22072788 DOI: 10.1091/mbc.E11-06-0489  0.8
2012 Flannagan RS, Jaumouillé V, Huynh KK, Plumb JD, Downey GP, Valvano MA, Grinstein S. Burkholderia cenocepacia disrupts host cell actin cytoskeleton by inactivating Rac and Cdc42. Cellular Microbiology. 14: 239-54. PMID 22023324 DOI: 10.1111/j.1462-5822.2011.01715.x  0.8
2011 Orlowski J, Grinstein S. Na+/H+ exchangers. Comprehensive Physiology. 1: 2083-100. PMID 23733698 DOI: 10.1002/cphy.c110020  0.8
2011 Lam GY, Fattouh R, Muise AM, Grinstein S, Higgins DE, Brumell JH. Listeriolysin O suppresses phospholipase C-mediated activation of the microbicidal NADPH oxidase to promote Listeria monocytogenes infection. Cell Host & Microbe. 10: 627-34. PMID 22177565 DOI: 10.1016/j.chom.2011.11.005  0.8
2011 Fairn GD, Hermansson M, Somerharju P, Grinstein S. Phosphatidylserine is polarized and required for proper Cdc42 localization and for development of cell polarity. Nature Cell Biology. 13: 1424-30. PMID 21964439 DOI: 10.1038/ncb2351  0.8
2011 Jaqaman K, Kuwata H, Touret N, Collins R, Trimble WS, Danuser G, Grinstein S. Cytoskeletal control of CD36 diffusion promotes its receptor and signaling function. Cell. 146: 593-606. PMID 21854984 DOI: 10.1016/j.cell.2011.06.049  0.8
2011 Kaniuk NA, Canadien V, Bagshaw RD, Bakowski M, Braun V, Landekic M, Mitra S, Huang J, Heo WD, Meyer T, Pelletier L, Andrews-Polymenis H, McClelland M, Pawson T, Grinstein S, et al. Salmonella exploits Arl8B-directed kinesin activity to promote endosome tubulation and cell-to-cell transfer. Cellular Microbiology. 13: 1812-23. PMID 21824248 DOI: 10.1111/j.1462-5822.2011.01663.x  0.8
2011 Golebiewska U, Kay JG, Masters T, Grinstein S, Im W, Pastor RW, Scarlata S, McLaughlin S. Evidence for a fence that impedes the diffusion of phosphatidylinositol 4,5-bisphosphate out of the forming phagosomes of macrophages. Molecular Biology of the Cell. 22: 3498-507. PMID 21795401 DOI: 10.1091/mbc.E11-02-0114  0.8
2011 Botelho RJ, Grinstein S. Phagocytosis. Current Biology : Cb. 21: R533-8. PMID 21783028 DOI: 10.1016/j.cub.2011.05.053  1
2011 Maures TJ, Su HW, Argetsinger LS, Grinstein S, Carter-Su C. Phosphorylation controls a dual-function polybasic nuclear localization sequence in the adapter protein SH2B1β to regulate its cellular function and distribution. Journal of Cell Science. 124: 1542-52. PMID 21486950 DOI: 10.1242/jcs.078949  0.8
2011 Alexander RT, Jaumouillé V, Yeung T, Furuya W, Peltekova I, Boucher A, Zasloff M, Orlowski J, Grinstein S. Membrane surface charge dictates the structure and function of the epithelial Na+/H+ exchanger. The Embo Journal. 30: 679-91. PMID 21245831 DOI: 10.1038/emboj.2010.356  0.8
2010 Flannagan RS, Harrison RE, Yip CM, Jaqaman K, Grinstein S. Dynamic macrophage "probing" is required for the efficient capture of phagocytic targets Journal of Cell Biology. 191: 1205-1218. PMID 21135140 DOI: 10.1083/jcb.201007056  0.8
2010 Bohdanowicz M, Cosío G, Backer JM, Grinstein S. Class I and class III phosphoinositide 3-kinases are required for actin polymerization that propels phagosomes. The Journal of Cell Biology. 191: 999-1012. PMID 21115805 DOI: 10.1083/jcb.201004005  0.8
2010 Huynh KK, Plumb JD, Downey GP, Valvano MA, Grinstein S. Inactivation of macrophage Rab7 by Burkholderia cenocepacia. Journal of Innate Immunity. 2: 522-33. PMID 20829607 DOI: 10.1159/000319864  0.8
2010 Steinberg BE, Huynh KK, Brodovitch A, Jabs S, Stauber T, Jentsch TJ, Grinstein S. A cation counterflux supports lysosomal acidification. The Journal of Cell Biology. 189: 1171-86. PMID 20566682 DOI: 10.1083/jcb.200911083  0.8
2010 Bakowski MA, Braun V, Lam GY, Yeung T, Heo WD, Meyer T, Finlay BB, Grinstein S, Brumell JH. The phosphoinositide phosphatase SopB manipulates membrane surface charge and trafficking of the Salmonella-containing vacuole. Cell Host & Microbe. 7: 453-62. PMID 20542249 DOI: 10.1016/j.chom.2010.05.011  0.8
2010 Braun V, Wong A, Landekic M, Hong WJ, Grinstein S, Brumell JH. Sorting nexin 3 (SNX3) is a component of a tubular endosomal network induced by Salmonella and involved in maturation of the Salmonella-containing vacuole. Cellular Microbiology. 12: 1352-67. PMID 20482551 DOI: 10.1111/j.1462-5822.2010.01476.x  0.8
2010 Lee HK, Mattei LM, Steinberg BE, Alberts P, Lee YH, Chervonsky A, Mizushima N, Grinstein S, Iwasaki A. In vivo requirement for Atg5 in antigen presentation by dendritic cells. Immunity. 32: 227-39. PMID 20171125 DOI: 10.1016/j.immuni.2009.12.006  0.8
2010 Koivusalo M, Welch C, Hayashi H, Scott CC, Kim M, Alexander T, Touret N, Hahn KM, Grinstein S. Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling. The Journal of Cell Biology. 188: 547-63. PMID 20156964 DOI: 10.1083/jcb.200908086  0.8
2010 Lee JS, Lee YM, Kim JY, Park HW, Grinstein S, Orlowski J, Kim E, Kim KH, Lee MG. BetaPix up-regulates Na+/H+ exchanger 3 through a Shank2-mediated protein-protein interaction. The Journal of Biological Chemistry. 285: 8104-13. PMID 20080968 DOI: 10.1074/jbc.M109.055079  0.8
2010 Casey JR, Grinstein S, Orlowski J. Sensors and regulators of intracellular pH. Nature Reviews. Molecular Cell Biology. 11: 50-61. PMID 19997129 DOI: 10.1038/nrm2820  0.8
2009 Fairn GD, Ogata K, Botelho RJ, Stahl PD, Anderson RA, De Camilli P, Meyer T, Wodak S, Grinstein S. An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis. The Journal of Cell Biology. 187: 701-14. PMID 19951917 DOI: 10.1083/jcb.200909025  0.8
2009 Erdman LK, Cosio G, Helmers AJ, Gowda DC, Grinstein S, Kain KC. CD36 and TLR interactions in inflammation and phagocytosis: implications for malaria. Journal of Immunology (Baltimore, Md. : 1950). 183: 6452-9. PMID 19864601 DOI: 10.4049/jimmunol.0901374  0.8
2009 Collins RF, Touret N, Kuwata H, Tandon NN, Grinstein S, Trimble WS. Uptake of oxidized low density lipoprotein by CD36 occurs by an actin-dependent pathway distinct from macropinocytosis. The Journal of Biological Chemistry. 284: 30288-97. PMID 19740737 DOI: 10.1074/jbc.M109.045104  0.8
2009 Botelho RJ, Harrison RE, Stone JC, Hancock JF, Philips MR, Jongstra-Bilen J, Mason D, Plumb J, Gold MR, Grinstein S. Localized diacylglycerol-dependent stimulation of Ras and Rap1 during phagocytosis. The Journal of Biological Chemistry. 284: 28522-32. PMID 19700408 DOI: 10.1074/jbc.M109.009514  0.8
2009 Alexander RT, Grinstein S. Tethering, recycling and activation of the epithelial sodium-proton exchanger, NHE3. The Journal of Experimental Biology. 212: 1630-7. PMID 19448073 DOI: 10.1242/jeb.027375  0.8
2009 Huang J, Canadien V, Lam GY, Steinberg BE, Dinauer MC, Magalhaes MA, Glogauer M, Grinstein S, Brumell JH. Activation of antibacterial autophagy by NADPH oxidases. Proceedings of the National Academy of Sciences of the United States of America. 106: 6226-31. PMID 19339495 DOI: 10.1073/pnas.0811045106  0.8
2009 Wang Y, Roche O, Yan MS, Finak G, Evans AJ, Metcalf JL, Hast BE, Hanna SC, Wondergem B, Furge KA, Irwin MS, Kim WY, Teh BT, Grinstein S, Park M, et al. Regulation of endocytosis via the oxygen-sensing pathway. Nature Medicine. 15: 319-24. PMID 19252501 DOI: 10.1038/nm.1922  0.8
2009 Sason H, Milgrom M, Weiss AM, Melamed-Book N, Balla T, Grinstein S, Backert S, Rosenshine I, Aroeti B. Enteropathogenic Escherichia coli subverts phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate upon epithelial cell infection. Molecular Biology of the Cell. 20: 544-55. PMID 18987340 DOI: 10.1091/mbc.E08-05-0516  0.8
2008 Mallo GV, Espina M, Smith AC, Terebiznik MR, Alemán A, Finlay BB, Rameh LE, Grinstein S, Brumell JH. SopB promotes phosphatidylinositol 3-phosphate formation on Salmonella vacuoles by recruiting Rab5 and Vps34. The Journal of Cell Biology. 182: 741-52. PMID 18725540 DOI: 10.1083/jcb.200804131  0.8
2008 Tian W, Li XJ, Stull ND, Ming W, Sun CI, Bissonnette SA, Yaffe MB, Grinstein S, Atkinson SJ, Dinauer MC. Fc{gamma}R-stimulated activation of the NADPH oxidase: Phosphoinositide- binding protein p40phox regulates NADPH oxidase activity after enzyme assembly on the phagosome Blood. 112: 3867-3877. PMID 18711001 DOI: 10.1182/blood-2007-11-126029  0.8
2008 Jaqaman K, Loerke D, Mettlen M, Kuwata H, Grinstein S, Schmid SL, Danuser G. Robust single-particle tracking in live-cell time-lapse sequences. Nature Methods. 5: 695-702. PMID 18641657 DOI: 10.1038/nmeth.1237  0.8
2005 Tse SM, Mason D, Botelho RJ, Chiu B, Reyland M, Hanada K, Inman RD, Grinstein S. Accumulation of diacylglycerol in the Chlamydia inclusion vacuole: possible role in the inhibition of host cell apoptosis. The Journal of Biological Chemistry. 280: 25210-5. PMID 15863503 DOI: 10.1074/jbc.M501980200  1
2005 Scott CC, Dobson W, Botelho RJ, Coady-Osberg N, Chavrier P, Knecht DA, Heath C, Stahl P, Grinstein S. Phosphatidylinositol-4,5-bisphosphate hydrolysis directs actin remodeling during phagocytosis. The Journal of Cell Biology. 169: 139-49. PMID 15809313 DOI: 10.1083/jcb.200412162  0.8
2004 Botelho RJ, Scott CC, Grinstein S. Phosphoinositide involvement in phagocytosis and phagosome maturation. Current Topics in Microbiology and Immunology. 282: 1-30. PMID 14594212  0.8
2003 Scott CC, Botelho RJ, Grinstein S. Phagosome maturation: a few bugs in the system. The Journal of Membrane Biology. 193: 137-52. PMID 12962275 DOI: 10.1007/s00232-002-2008-2  0.8
2003 Gu H, Botelho RJ, Yu M, Grinstein S, Neel BG. Critical role for scaffolding adapter Gab2 in FcγR-mediated phagocytosis Journal of Cell Biology. 161: 1151-1161. PMID 12821647 DOI: 10.1083/jcb.200212158  0.8
2003 Dombrosky-Ferlan P, Grishin A, Botelho RJ, Sampson M, Wang L, Rudert WA, Grinstein S, Corey SJ. Felic (CIP4b), a novel binding partner with the Src kinase Lyn and Cdc42, localizes to the phagocytic cup. Blood. 101: 2804-9. PMID 12456510 DOI: 10.1182/blood-2002-03-0851  1
2002 Botelho RJ, Tapper H, Furuya W, Mojdami D, Grinstein S. Fc gamma R-mediated phagocytosis stimulates localized pinocytosis in human neutrophils. Journal of Immunology (Baltimore, Md. : 1950). 169: 4423-9. PMID 12370376  1
2002 Vieira OV, Botelho RJ, Grinstein S. Phagosome maturation: aging gracefully. The Biochemical Journal. 366: 689-704. PMID 12061891 DOI: 10.1042/BJ20020691  1
2001 Vieira OV, Botelho RJ, Rameh L, Brachmann SM, Matsuo T, Davidson HW, Schreiber A, Backer JM, Cantley LC, Grinstein S. Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation. The Journal of Cell Biology. 155: 19-25. PMID 11581283 DOI: 10.1083/jcb.200107069  1
2001 Hackam DJ, Botelho RJ, Sjolin C, Rotstein OD, Robinson JM, Schreiber AD, Grinstein S. Indirect role for COPI in the completion of FCgamma receptor-mediated phagocytosis. The Journal of Biological Chemistry. 276: 18200-8. PMID 11279223 DOI: 10.1074/jbc.M102009200  0.8
2000 Botelho RJ, Teruel M, Dierckman R, Anderson R, Wells A, York JD, Meyer T, Grinstein S. Localized biphasic changes in phosphatidylinositol-4,5-bisphosphate at sites of phagocytosis. The Journal of Cell Biology. 151: 1353-68. PMID 11134066 DOI: 10.1083/jcb.151.7.1353  1
2000 Botelho RJ, Hackam DJ, Schreiber AD, Grinstein S. Role of COPI in phagosome maturation. The Journal of Biological Chemistry. 275: 15717-27. PMID 10748188 DOI: 10.1074/jbc.M910068199  0.8
2000 Schapiro FB, Grinstein S. Determinants of the pH of the Golgi complex. The Journal of Biological Chemistry. 275: 21025-32. PMID 10748071 DOI: 10.1074/jbc.M002386200  1
1999 Downey GP, Botelho RJ, Butler JR, Moltyaner Y, Chien P, Schreiber AD, Grinstein S. Phagosomal maturation, acidification, and inhibition of bacterial growth in nonphagocytic cells transfected with FcgammaRIIA receptors. The Journal of Biological Chemistry. 274: 28436-44. PMID 10497205 DOI: 10.1074/jbc.274.40.28436  0.8
1998 Schapiro FB, Lingwood C, Furuya W, Grinstein S. pH-independent retrograde targeting of glycolipids to the Golgi complex. The American Journal of Physiology. 274: C319-32. PMID 9486120  0.8
Low-probability matches
2011 Koivusalo M, Steinberg BE, Mason D, Grinstein S. In situ measurement of the electrical potential across the lysosomal membrane using FRET. Traffic (Copenhagen, Denmark). 12: 972-82. PMID 21554506 DOI: 10.1111/j.1600-0854.2011.01215.x  0.28
2009 Yeung T, Heit B, Dubuisson JF, Fairn GD, Chiu B, Inman R, Kapus A, Swanson M, Grinstein S. Contribution of phosphatidylserine to membrane surface charge and protein targeting during phagosome maturation. The Journal of Cell Biology. 185: 917-28. PMID 19487458 DOI: 10.1083/jcb.200903020  0.28
2010 Gramoun A, Goto T, Nordström T, Rotstein OD, Grinstein S, Heersche JN, Manolson MF. Bone matrix proteins and extracellular acidification: potential co-regulators of osteoclast morphology. Journal of Cellular Biochemistry. 111: 350-61. PMID 20506338 DOI: 10.1002/jcb.22705  0.2
2018 Truong D, Boddy KC, Canadien V, Brabant D, Fairn GD, D'Costa VM, Coyaud E, Raught B, Perez-Sala D, Park WS, Do Heo W, Grinstein S, Brumell JH. Salmonella exploits host Rho GTPase signalling pathways through the phosphatase activity of SopB. Cellular Microbiology. e12938. PMID 30010242 DOI: 10.1111/cmi.12938  0.16
2017 Hirama T, Lu SM, Kay JG, Maekawa M, Kozlov MM, Grinstein S, Fairn GD. Membrane curvature induced by proximity of anionic phospholipids can initiate endocytosis. Nature Communications. 8: 1393. PMID 29123120 DOI: 10.1038/s41467-017-01554-9  0.16
2017 Stefan CJ, Trimble WS, Grinstein S, Drin G, Reinisch K, De Camilli P, Cohen S, Valm AM, Lippincott-Schwartz J, Levine TP, Iaea DB, Maxfield FR, Futter CE, Eden ER, Judith D, et al. Membrane dynamics and organelle biogenesis-lipid pipelines and vesicular carriers. Bmc Biology. 15: 102. PMID 29089042 DOI: 10.1186/s12915-017-0432-0  0.16
2017 Hirama T, Das R, Yang Y, Ferguson C, Won A, Yip CM, Kay JG, Grinstein S, Parton RG, Fairn GD. Phosphatidylserine dictates the assembly and dynamics of caveolae in the plasma membrane. The Journal of Biological Chemistry. PMID 28698382 DOI: 10.1074/jbc.M117.791400  0.16
2017 Levin R, Hammond GR, Balla T, De Camilli P, Fairn GD, Grinstein S. Multiphasic dynamics of phosphatidylinositol 4-phosphate during phagocytosis. Molecular Biology of the Cell. 28: 128-140. PMID 28035045 DOI: 10.1091/mbc.E16-06-0451  0.16
2017 Lu SM, Grinstein S, Fairn GD. Quantitative Live-Cell Fluorescence Microscopy During Phagocytosis. Methods in Molecular Biology (Clifton, N.J.). 1519: 79-91. PMID 27815874 DOI: 10.1007/978-1-4939-6581-6_6  0.16
2016 Ostrowski PP, Fairn GD, Grinstein S, Johnson DE. Cresyl violet: a superior fluorescent lysosomal marker. Traffic (Copenhagen, Denmark). PMID 27621028 DOI: 10.1111/tra.12447  0.16
2013 Schlam D, Bohdanowicz M, Chatgilialoglu A, Chatilialoglu A, Steinberg BE, Ueyama T, Du G, Grinstein S, Fairn GD. Diacylglycerol kinases terminate diacylglycerol signaling during the respiratory burst leading to heterogeneous phagosomal NADPH oxidase activation. The Journal of Biological Chemistry. 288: 23090-104. PMID 23814057 DOI: 10.1074/jbc.M113.457606  0.16
2012 Fairn GD, Grinstein S. Cell biology. Precursor or charge supplier? Science (New York, N.Y.). 337: 653-4. PMID 22879491 DOI: 10.1126/science.1227096  0.16
2012 Fairn GD, Grinstein S. How nascent phagosomes mature to become phagolysosomes. Trends in Immunology. 33: 397-405. PMID 22560866 DOI: 10.1016/  0.16
2011 Kay JG, Grinstein S. Sensing phosphatidylserine in cellular membranes. Sensors (Basel, Switzerland). 11: 1744-55. PMID 22319379 DOI: 10.3390/s110201744  0.16
2011 Carraro-Lacroix LR, Jaumouillé V, Fairn GD, Grinstein S. A weak base-generating system suitable for selective manipulation of lysosomal pH. Traffic (Copenhagen, Denmark). 12: 1490-500. PMID 21819499 DOI: 10.1111/j.1600-0854.2011.01266.x  0.16
2011 Fairn GD, Schieber NL, Ariotti N, Murphy S, Kuerschner L, Webb RI, Grinstein S, Parton RG. High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine. The Journal of Cell Biology. 194: 257-75. PMID 21788369 DOI: 10.1083/jcb.201012028  0.16
2014 Canton J, Grinstein S. Priming and activation of NADPH oxidases in plants and animals. Trends in Immunology. 35: 405-7. PMID 25127055 DOI: 10.1016/  0.12
2016 Johnston CW, Plumb J, Li X, Grinstein S, Magarvey NA. Informatic analysis reveals Legionella as a source of novel natural products. Synthetic and Systems Biotechnology. 1: 130-136. PMID 29062936 DOI: 10.1016/j.synbio.2015.12.001  0.08
2015 Freeman SA, Jaumouillé V, Choi K, Hsu BE, Wong HS, Abraham L, Graves ML, Coombs D, Roskelley CD, Das R, Grinstein S, Gold MR. Erratum: Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor. Nature Communications. 6: 7015. PMID 25881569 DOI: 10.1038/ncomms8015  0.08
2015 Canton J, Grinstein S. Measuring lysosomal pH by fluorescence microscopy. Methods in Cell Biology. 126: 85-99. PMID 25665442 DOI: 10.1016/bs.mcb.2014.10.021  0.08
2014 Zhang F, Wang Z, Lu M, Yonekubo Y, Liang X, Zhang Y, Wu P, Zhou Y, Grinstein S, Hancock JF, Du G. Temporal production of the signaling lipid phosphatidic acid by phospholipase D2 determines the output of extracellular signal-regulated kinase signaling in cancer cells. Molecular and Cellular Biology. 34: 84-95. PMID 24164897 DOI: 10.1128/MCB.00987-13  0.08
2013 Kay JG, Grinstein S. Phosphatidylserine-mediated cellular signaling. Advances in Experimental Medicine and Biology. 991: 177-93. PMID 23775696 DOI: 10.1007/978-94-007-6331-9_10  0.08
2016 Jaumouillé V, Grinstein S. Molecular Mechanisms of Phagosome Formation. Microbiology Spectrum. 4. PMID 27337463 DOI: 10.1128/microbiolspec.MCHD-0013-2015  0.04
2016 Johnson DE, Ostrowski P, Jaumouillé V, Grinstein S. The position of lysosomes within the cell determines their luminal pH. The Journal of Cell Biology. 212: 677-92. PMID 26975849 DOI: 10.1083/jcb.201507112  0.04
2014 Canton J, Khezri R, Glogauer M, Grinstein S. Contrasting phagosome pH regulation and maturation in human M1 and M2 macrophages. Molecular Biology of the Cell. 25: 3330-41. PMID 25165138 DOI: 10.1091/mbc.E14-05-0967  0.04
2012 Kay JG, Koivusalo M, Ma X, Wohland T, Grinstein S. Phosphatidylserine dynamics in cellular membranes. Molecular Biology of the Cell. 23: 2198-212. PMID 22496416 DOI: 10.1091/mbc.E11-11-0936  0.04
2012 Flannagan RS, Jaumouillé V, Grinstein S. The cell biology of phagocytosis. Annual Review of Pathology. 7: 61-98. PMID 21910624 DOI: 10.1146/annurev-pathol-011811-132445  0.04
2011 Jaumouillé V, Grinstein S. Receptor mobility, the cytoskeleton, and particle binding during phagocytosis. Current Opinion in Cell Biology. 23: 22-9. PMID 21074980 DOI: 10.1016/  0.04
2011 Heit B, Yeung T, Grinstein S. Changes in mitochondrial surface charge mediate recruitment of signaling molecules during apoptosis. American Journal of Physiology. Cell Physiology. 300: C33-41. PMID 20926778 DOI: 10.1152/ajpcell.00139.2010  0.04
2019 Heybrock S, Kanerva K, Meng Y, Ing C, Liang A, Xiong ZJ, Weng X, Ah Kim Y, Collins R, Trimble W, Pomès R, Privé GG, Annaert W, Schwake M, Heeren J, ... ... Grinstein S, et al. Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export. Nature Communications. 10: 3521. PMID 31387993 DOI: 10.1038/s41467-019-11425-0  0.01
2019 Ostrowski PP, Freeman SA, Fairn G, Grinstein S. Dynamic Podosome-Like Structures in Nascent Phagosomes Are Coordinated by Phosphoinositides. Developmental Cell. PMID 31231039 DOI: 10.1016/j.devcel.2019.05.028  0.01
2019 Marques PE, Nyegaard S, Collins RF, Troise F, Freeman SA, Trimble WS, Grinstein S. Multimerization and Retention of the Scavenger Receptor SR-B1 in the Plasma Membrane. Developmental Cell. PMID 31231038 DOI: 10.1016/j.devcel.2019.05.026  0.01
2019 Westman J, Grinstein S, Maxson ME. Revisiting the role of calcium in phagosome formation and maturation. Journal of Leukocyte Biology. PMID 31091355 DOI: 10.1002/JLB.MR1118-444R  0.01
2019 Doodnauth SA, Grinstein S, Maxson ME. Constitutive and stimulated macropinocytosis in macrophages: roles in immunity and in the pathogenesis of atherosclerosis. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 374: 20180147. PMID 30967001 DOI: 10.1098/rstb.2018.0147  0.01
2018 Mylvaganam SM, Grinstein S, Freeman SA. Picket-fences in the plasma membrane: functions in immune cells and phagocytosis. Seminars in Immunopathology. PMID 30209546 DOI: 10.1007/s00281-018-0705-x  0.01
2018 Westman J, Moran G, Mogavero S, Hube B, Grinstein S. Candida albicans Hyphal Expansion Causes Phagosomal Membrane Damage and Luminal Alkalinization. Mbio. 9. PMID 30206168 DOI: 10.1128/mBio.01226-18  0.01
2018 Freeman SA, Grinstein S. Resolution of macropinosomes, phagosomes, and autolysosomes: osmotically-driven shrinkage enables tubulation and vesiculation. Traffic (Copenhagen, Denmark). PMID 30159984 DOI: 10.1111/tra.12614  0.01
2018 O'Meara TR, Duah K, Guo CX, Maxson ME, Gaudet RG, Koselny K, Wellington M, Powers ME, MacAlpine J, O'Meara MJ, Veri AO, Grinstein S, Noble SM, Krysan D, Gray-Owen SD, et al. High-Throughput Screening Identifies Genes Required for Induction of Macrophage Pyroptosis. Mbio. 9. PMID 30131363 DOI: 10.1128/mBio.01581-18  0.01
2018 Schlam D, Grinstein S, Freeman SA. Screening for Rho GTPase Modulators in Actin-Dependent Processes Exemplified by Phagocytosis. Methods in Molecular Biology (Clifton, N.J.). 1821: 107-127. PMID 30062408 DOI: 10.1007/978-1-4939-8612-5_8  0.01
2018 Montaño F, Grinstein S, Levin R. Quantitative Phagocytosis Assays in Primary and Cultured Macrophages. Methods in Molecular Biology (Clifton, N.J.). 1784: 151-163. PMID 29761397 DOI: 10.1007/978-1-4939-7837-3_15  0.01
2018 Walpole GFW, Grinstein S, Westman J. The role of lipids in host-pathogen interactions. Iubmb Life. 70: 384-392. PMID 29573124 DOI: 10.1002/iub.1737  0.01
2018 Maxson ME, Naj X, O'Meara TR, Plumb JD, Cowen LE, Grinstein S. Integrin-based diffusion barrier separates membrane domains enabling formation of microbiostatic frustrated phagosomes. Elife. 7. PMID 29553370 DOI: 10.7554/eLife.34798  0.01
2018 Vega AR, Freeman SA, Grinstein S, Jaqaman K. Multistep Track Segmentation and Motion Classification for Transient Mobility Analysis. Biophysical Journal. 114: 1018-1025. PMID 29539390 DOI: 10.1016/j.bpj.2018.01.012  0.01
2018 Rabani R, Volchuk A, Jerkic M, Ormesher L, Garces-Ramirez L, Canton J, Masterson C, Gagnon S, Tatham KC, Marshall J, Grinstein S, Laffey JG, Szaszi K, Curley GF. Mesenchymal stem cells enhance NOX2 dependent ROS production and bacterial killing in macrophages during sepsis. The European Respiratory Journal. PMID 29519920 DOI: 10.1183/13993003.02021-2017  0.01
2018 Niedergang F, Grinstein S. How to build a phagosome: new concepts for an old process. Current Opinion in Cell Biology. 50: 57-63. PMID 29471269 DOI: 10.1016/  0.01
2018 Freeman SA, Vega A, Riedl M, Collins RF, Ostrowski PP, Woods EC, Bertozzi CR, Tammi MI, Lidke DS, Johnson P, Mayor S, Jaqaman K, Grinstein S. Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement. Cell. 172: 305-317.e10. PMID 29328918 DOI: 10.1016/j.cell.2017.12.023  0.01
2017 Sharfe N, Karanxha A, Dadi H, Merico D, Chitayat D, Herbrick JA, Freeman S, Grinstein S, Roifman CM. Dual loss of p110δ PI3-kinase and SKAP (KNSTRN) expression leads to combined immunodeficiency and multisystem syndromic features. The Journal of Allergy and Clinical Immunology. PMID 29180244 DOI: 10.1016/j.jaci.2017.10.033  0.01
2017 Redka DS, Gütschow M, Grinstein S, Canton J. Differential ability of pro-inflammatory and anti-inflammatory macrophages to perform macropinocytosis. Molecular Biology of the Cell. PMID 29093026 DOI: 10.1091/mbc.E17-06-0419  0.01
2017 Lim JJ, Grinstein S, Roth Z. Diversity and Versatility of Phagocytosis: Roles in Innate Immunity, Tissue Remodeling, and Homeostasis. Frontiers in Cellular and Infection Microbiology. 7: 191. PMID 28589095 DOI: 10.3389/fcimb.2017.00191  0.01
2017 Marques PE, Grinstein S, Freeman SA. SnapShot:Macropinocytosis. Cell. 169: 766-766.e1. PMID 28475901 DOI: 10.1016/j.cell.2017.04.031  0.01
2017 Canton J, Grinstein S. Measuring Phagosomal pH by Fluorescence Microscopy. Methods in Molecular Biology (Clifton, N.J.). 1519: 185-199. PMID 27815880 DOI: 10.1007/978-1-4939-6581-6_12  0.01
2016 Freeman SA, Grinstein S. Phagocytosis: How Macrophages Tune Their Non-professional Counterparts. Current Biology : Cb. 26: R1279-R1282. PMID 27997839 DOI: 10.1016/j.cub.2016.10.059  0.01
2016 Ostrowski PP, Grinstein S, Freeman SA. Diffusion Barriers, Mechanical Forces, and the Biophysics of Phagocytosis. Developmental Cell. 38: 135-46. PMID 27459066 DOI: 10.1016/j.devcel.2016.06.023  0.01
2016 Cemma M, Grinstein S, Brumell JH. Autophagy Proteins are not Universally Required for Phagosome Maturation. Autophagy. 0. PMID 27310610 DOI: 10.1080/15548627.2016.1191724  0.01
2016 Canton J, Schlam D, Breuer C, Gütschow M, Glogauer M, Grinstein S. Calcium-sensing receptors signal constitutive macropinocytosis and facilitate the uptake of NOD2 ligands in macrophages. Nature Communications. 7: 11284. PMID 27050483 DOI: 10.1038/ncomms11284  0.01
2015 Trimble WS, Grinstein S. Barriers to the free diffusion of proteins and lipids in the plasma membrane. The Journal of Cell Biology. 208: 259-71. PMID 25646084 DOI: 10.1083/jcb.201410071  0.01
2015 Scherf A, Grinstein S. Cellular microbiology editorial letter. Cellular Microbiology. 17: 1. PMID 25523229 DOI: 10.1111/cmi.12402  0.01
2014 Maxson ME, Grinstein S. The vacuolar-type H⁺-ATPase at a glance - more than a proton pump. Journal of Cell Science. 127: 4987-93. PMID 25453113 DOI: 10.1242/jcs.158550  0.01
2014 Gelabert-Baldrich M, Soriano-Castell D, Calvo M, Lu A, Viña-Vilaseca A, Rentero C, Pol A, Grinstein S, Enrich C, Tebar F. Dynamics of KRas on endosomes: involvement of acidic phospholipids in its association. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 3023-37. PMID 24719356 DOI: 10.1096/fj.13-241158  0.01
2014 Steinberg BE, Magalhaes MA, Grinstein S. Expression of genetically encoded fluorescent probes to monitor phospholipid dynamics in live neutrophils. Methods in Molecular Biology (Clifton, N.J.). 1124: 269-77. PMID 24504958 DOI: 10.1007/978-1-62703-845-4_17  0.01
2013 Canton J, Neculai D, Grinstein S. Scavenger receptors in homeostasis and immunity. Nature Reviews. Immunology. 13: 621-34. PMID 23928573 DOI: 10.1038/nri3515  0.01
2013 Bohdanowicz M, Grinstein S. Role of phospholipids in endocytosis, phagocytosis, and macropinocytosis. Physiological Reviews. 93: 69-106. PMID 23303906 DOI: 10.1152/physrev.00002.2012  0.01
2012 Sarantis H, Grinstein S. Subversion of phagocytosis for pathogen survival. Cell Host & Microbe. 12: 419-31. PMID 23084912 DOI: 10.1016/j.chom.2012.09.001  0.01
2012 Grinstein S. Phagocytosis here and now. Traffic (Copenhagen, Denmark). 13: 1041. PMID 22672314 DOI: 10.1111/j.1600-0854.2012.01383.x  0.01
2012 Lee BH, Hwang DM, Palaniyar N, Grinstein S, Philpott DJ, Hu J. Activation of P2X(7) receptor by ATP plays an important role in regulating inflammatory responses during acute viral infection. Plos One. 7: e35812. PMID 22558229 DOI: 10.1371/journal.pone.0035812  0.01
2012 Grinstein S. Sergio Grinstein: phagocytosis step by step. Interview by Caitlin Sedwick. The Journal of Cell Biology. 196: 392-3. PMID 22351924 DOI: 10.1083/jcb.1964pi  0.01
2012 Sarantis H, Grinstein S. Monitoring phospholipid dynamics during phagocytosis: application of genetically-encoded fluorescent probes. Methods in Cell Biology. 108: 429-44. PMID 22325613 DOI: 10.1016/B978-0-12-386487-1.00019-5  0.01
2011 Flannagan RS, Grinstein S. Editorial: Fly fishing with RNAi catches novel effectors of phagocytosis. Journal of Leukocyte Biology. 89: 643-5. PMID 21532049 DOI: 10.1189/jlb.1210653  0.01
2010 Lee BH, Kushwah R, Wu J, Ng P, Palaniyar N, Grinstein S, Philpott DJ, Hu J. Adenoviral vectors stimulate innate immune responses in macrophages through cross-talk with epithelial cells. Immunology Letters. 134: 93-102. PMID 20850478 DOI: 10.1016/j.imlet.2010.09.003  0.01
2010 Grinstein S. Imaging signal transduction during phagocytosis: phospholipids, surface charge, and electrostatic interactions. American Journal of Physiology. Cell Physiology. 299: C876-81. PMID 20739621 DOI: 10.1152/ajpcell.00342.2010  0.01
2010 Bohdanowicz M, Grinstein S. Vesicular traffic: a Rab SANDwich. Current Biology : Cb. 20: R311-4. PMID 20392419 DOI: 10.1016/j.cub.2010.02.030  0.01
2010 Leventis PA, Grinstein S. The distribution and function of phosphatidylserine in cellular membranes. Annual Review of Biophysics. 39: 407-27. PMID 20192774 DOI: 10.1146/annurev.biophys.093008.131234  0.01
2010 Flannagan RS, Grinstein S. The application of fluorescent probes for the analysis of lipid dynamics during phagocytosis. Methods in Molecular Biology (Clifton, N.J.). 591: 121-34. PMID 19957127 DOI: 10.1007/978-1-60761-404-3_7  0.01
2009 Fortier A, Doiron K, Saleh M, Grinstein S, Gros P. Restriction of Legionella pneumophila replication in macrophages requires concerted action of the transcriptional regulators Irf1 and Irf8 and nod-like receptors Naip5 and Nlrc4. Infection and Immunity. 77: 4794-805. PMID 19720760 DOI: 10.1128/IAI.01546-08  0.01
2009 Flannagan RS, Cosío G, Grinstein S. Antimicrobial mechanisms of phagocytes and bacterial evasion strategies. Nature Reviews. Microbiology. 7: 355-66. PMID 19369951 DOI: 10.1038/nrmicro2128  0.01
2009 Steinberg BE, Grinstein S. Analysis of macrophage phagocytosis: quantitative assays of phagosome formation and maturation using high-throughput fluorescence microscopy. Methods in Molecular Biology (Clifton, N.J.). 531: 45-56. PMID 19347310 DOI: 10.1007/978-1-59745-396-7_4  0.01
2009 Li XJ, Tian W, Stull ND, Grinstein S, Atkinson S, Dinauer MC. A fluorescently tagged C-terminal fragment of p47phox detects NADPH oxidase dynamics during phagocytosis. Molecular Biology of the Cell. 20: 1520-32. PMID 19129478 DOI: 10.1091/mbc.E08-06-0620  0.01
2009 Koivusalo M, Kapus A, Grinstein S. Sensors, transducers, and effectors that regulate cell size and shape. The Journal of Biological Chemistry. 284: 6595-9. PMID 19004817 DOI: 10.1074/jbc.R800049200  0.01
2008 Huynh KK, Gershenzon E, Grinstein S. Cholesterol accumulation by macrophages impairs phagosome maturation. The Journal of Biological Chemistry. 283: 35745-55. PMID 18955491 DOI: 10.1074/jbc.M806232200  0.01
2008 Huynh KK, Grinstein S. Phagocytosis: dynamin's dual role in phagosome biogenesis. Current Biology : Cb. 18: R563-5. PMID 18606127 DOI: 10.1016/j.cub.2008.05.032  0.01
2008 Steinberg BE, Grinstein S. Pathogen destruction versus intracellular survival: the role of lipids as phagosomal fate determinants. The Journal of Clinical Investigation. 118: 2002-11. PMID 18523652 DOI: 10.1172/JCI35433  0.01
2007 Steinberg BE, Grinstein S. Assessment of phagosome formation and maturation by fluorescence microscopy. Methods in Molecular Biology (Clifton, N.J.). 412: 289-300. PMID 18453119 DOI: 10.1007/978-1-59745-467-4_19  0.01
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