Michel Roberge - Publications

University of British Columbia, Vancouver, Vancouver, BC, Canada 

117 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Hosseini-Farahabadi S, Baradaran-Heravi A, Zimmerman C, Choi K, Flibotte S, Roberge M. Small molecule Y-320 stimulates ribosome biogenesis, protein synthesis, and aminoglycoside-induced premature termination codon readthrough. Plos Biology. 19: e3001221. PMID 33939688 DOI: 10.1371/journal.pbio.3001221  0.44
2021 Baradaran-Heravi A, Balgi AD, Hosseini-Farahabadi S, Choi K, Has C, Roberge M. Effect of small molecule eRF3 degraders on premature termination codon readthrough. Nucleic Acids Research. PMID 33764477 DOI: 10.1093/nar/gkab194  0.4
2021 Slaine PD, Kleer M, Duguay BA, Pringle ES, Kadijk E, Ying S, Balgi A, Roberge M, McCormick C, Khaperskyy DA. Thiopurines activate an antiviral unfolded protein response that blocks influenza A virus glycoprotein accumulation. Journal of Virology. PMID 33762409 DOI: 10.1128/JVI.00453-21  0.56
2020 Gerak CAN, Zhang SM, Balgi AD, Sadowski IJ, Sessions RB, McIntosh LP, Roberge M. A Multipronged Screening Approach Targeting Inhibition of ETV6 PNT Domain Polymerization. Slas Discovery : Advancing Life Sciences R & D. 2472555220979599. PMID 33345679 DOI: 10.1177/2472555220979599  0.4
2020 Attwood KM, Robichaud A, Westhaver LP, Castle EL, Brandman DM, Balgi AD, Roberge M, Colp P, Croul S, Kim I, McCormick C, Corcoran JA, Weeks A. Raloxifene prevents stress granule dissolution, impairs translational control and promotes cell death during hypoxia in glioblastoma cells. Cell Death & Disease. 11: 989. PMID 33203845 DOI: 10.1038/s41419-020-03159-5  0.4
2020 Duncan MC, Onguéné PA, Kihara I, Nebangwa DN, Naidu ME, Williams DE, Balgi AD, Andrae-Marobela K, Roberge M, Andersen RJ, Niikura M, Ntie-Kang F, Tietjen I. Virtual Screening Identifies Chebulagic Acid as an Inhibitor of the M2(S31N) Viral Ion Channel and Influenza A Virus. Molecules (Basel, Switzerland). 25. PMID 32599753 DOI: 10.3390/Molecules25122903  0.56
2020 Frew J, Baradaran-Heravi A, Balgi AD, Wu X, Yan TD, Arns S, Shidmoossavee FS, Tan J, Jaquith JB, Jansen-West KR, Lynn FC, Gao FB, Petrucelli L, Feldman HH, Mackenzie IR, ... Roberge M, et al. Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency. Molecular Neurodegeneration. 15: 21. PMID 32178712 DOI: 10.1186/S13024-020-00369-5  0.4
2019 Rabea SM, Baradaran-Heravi A, Balgi AD, Krause A, Hosseini Farahabadi S, Roberge M, Grierson DS. 2-Aminothiazole-4-carboxamides Enhance Readthrough of Premature Termination Codons by Aminoglycosides. Acs Medicinal Chemistry Letters. 10: 726-731. PMID 31097990 DOI: 10.1021/Acsmedchemlett.8B00610  0.4
2017 Morris EJ, Kawamura E, Gillespie JA, Balgi A, Kannan N, Muller WJ, Roberge M, Dedhar S. Stat3 regulates centrosome clustering in cancer cells via Stathmin/PLK1. Nature Communications. 8: 15289. PMID 28474672 DOI: 10.1038/Ncomms15289  0.56
2017 Baradaran-Heravi A, Niesser J, Balgi AD, Choi K, Zimmerman C, South AP, Anderson HJ, Strynadka NC, Bally MB, Roberge M. Gentamicin B1 is a minor gentamicin component with major nonsense mutation suppression activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 28289221 DOI: 10.1073/Pnas.1620982114  0.44
2017 Robichaud A, Roberge M, Balgi A, McCormick C, Weeks A. Csig-18. Raloxifene Sensitizes Glioblastoma Cells To Hypoxia-Induced Death Through Inhibition Of Rna Stress Granule Dissolution Neuro-Oncology. 19. DOI: 10.1093/Neuonc/Nox168.212  0.56
2016 Huang S, Balgi A, Pan Y, Li M, Zhang X, Du L, Zhou M, Roberge M, Li X. Identification of methylosome components as negative regulators of plant immunity using chemical genetics. Molecular Plant. PMID 27756575 DOI: 10.1016/J.Molp.2016.10.006  0.56
2016 Mathew MD, Mathew ND, Miller A, Simpson M, Au V, Garland S, Gestin M, Edgley ML, Flibotte S, Balgi A, Chiang J, Giaever G, Dean P, Tung A, Roberge M, et al. Using C. elegans Forward and Reverse Genetics to Identify New Compounds with Anthelmintic Activity. Plos Neglected Tropical Diseases. 10: e0005058. PMID 27755544 DOI: 10.1371/Journal.Pntd.0005058  0.56
2016 Baradaran-Heravi A, Balgi AD, Zimmerman C, Choi K, Shidmoossavee FS, Tan JS, Bergeaud C, Krause A, Flibotte S, Shimizu Y, Anderson HJ, Mouly V, Jan E, Pfeifer T, Jaquith JB, ... Roberge M, et al. Novel small molecules potentiate premature termination codon readthrough by aminoglycosides. Nucleic Acids Research. PMID 27407112 DOI: 10.1093/Nar/Gkw638  1
2016 Arns S, Balgi AD, Shimizu Y, Pfeifer TA, Kumar N, Shidmoossavee FS, Sun S, Tai SS, Agafitei O, Jaquith JB, Bourque E, Niikura M, Roberge M. Novel spirothiazamenthane inhibitors of the influenza A M2 proton channel. European Journal of Medicinal Chemistry. 120: 64-73. PMID 27187859 DOI: 10.1016/j.ejmech.2016.05.008  0.4
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin J, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Roberge M, et al. Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 Autophagy. 12: 443-443. PMID 26902590 DOI: 10.1080/15548627.2016.1147886  0.4
2014 Donohue E, Balgi AD, Komatsu M, Roberge M. Induction of Covalently Crosslinked p62 Oligomers with Reduced Binding to Polyubiquitinated Proteins by the Autophagy Inhibitor Verteporfin. Plos One. 9: e114964. PMID 25494214 DOI: 10.1371/Journal.Pone.0114964  1
2014 Yang YH, Vilin YY, Roberge M, Kurata HT, Johnson JD. Multiparameter screening reveals a role for Na+ channels in cytokine-induced β-cell death. Molecular Endocrinology (Baltimore, Md.). 28: 406-17. PMID 24438339 DOI: 10.1210/Me.2013-1257  1
2014 Donohue E, Balgi AD, Komatsu M, Roberge M. Effect of verteporfin-induced high-MW p62 on its association with polyubiquitinated proteins and LC3. Plos One. DOI: 10.1371/Journal.Pone.0114964.G006  0.56
2013 Dragowska WH, Weppler SA, Wang JC, Wong LY, Kapanen AI, Rawji JS, Warburton C, Qadir MA, Donohue E, Roberge M, Gorski SM, Gelmon KA, Bally MB. Induction of autophagy is an early response to gefitinib and a potential therapeutic target in breast cancer. Plos One. 8: e76503. PMID 24146879 DOI: 10.1371/Journal.Pone.0076503  1
2013 Kawamura E, Fielding AB, Kannan N, Balgi A, Eaves CJ, Roberge M, Dedhar S. Identification of novel small molecule inhibitors of centrosome clustering in cancer cells. Oncotarget. 4: 1763-76. PMID 24091544 DOI: 10.18632/Oncotarget.1198  1
2013 Donohue E, Thomas A, Maurer N, Manisali I, Zeisser-Labouebe M, Zisman N, Anderson HJ, Ng SS, Webb M, Bally M, Roberge M. The autophagy inhibitor verteporfin moderately enhances the antitumor activity of gemcitabine in a pancreatic ductal adenocarcinoma model. Journal of Cancer. 4: 585-96. PMID 24069069 DOI: 10.7150/Jca.7030  0.56
2013 Forestieri R, Donohue E, Balgi A, Roberge M, Andersen RJ. Synthesis of clionamine B, an autophagy stimulating aminosteroid isolated from the sponge Cliona celata. Organic Letters. 15: 3918-21. PMID 23869546 DOI: 10.1021/Ol4016783  1
2013 Austin P, Freeman SA, Gray CA, Gold MR, Vogl AW, Andersen RJ, Roberge M, Roskelley CD. The invasion inhibitor sarasinoside A1 reverses mesenchymal tumor transformation in an E-cadherin-independent manner. Molecular Cancer Research : McR. 11: 530-40. PMID 23399642 DOI: 10.1158/1541-7786.Mcr-12-0385  1
2013 Balgi AD, Wang J, Cheng DY, Ma C, Pfeifer TA, Shimizu Y, Anderson HJ, Pinto LH, Lamb RA, DeGrado WF, Roberge M. Inhibitors of the influenza A virus M2 proton channel discovered using a high-throughput yeast growth restoration assay. Plos One. 8: e55271. PMID 23383318 DOI: 10.1371/Journal.Pone.0055271  1
2013 Towle KM, Chaytor JL, Liu H, Austin P, Roberge M, Roskelley CD, Vederas JC. Synthesis and biological studies of neopetrosiamides as inhibitors of cancer cell invasion. Organic & Biomolecular Chemistry. 11: 1476-81. PMID 23334605 DOI: 10.1039/C3Ob27238A  1
2013 Zimmerman C, Austin P, Khong A, McLeod S, Bean B, Forestieri R, Andersen RJ, Jan E, Roberge M, Roskelley CD. The small molecule genkwanine M induces single mode, mesenchymal tumor cell motility. Experimental Cell Research. 319: 908-17. PMID 23333560 DOI: 10.1016/J.Yexcr.2013.01.005  1
2013 Tam YY, Chen S, Zaifman J, Tam YK, Lin PJ, Ansell S, Roberge M, Ciufolini MA, Cullis PR. Small molecule ligands for enhanced intracellular delivery of lipid nanoparticle formulations of siRNA. Nanomedicine : Nanotechnology, Biology, and Medicine. 9: 665-74. PMID 23219877 DOI: 10.1016/J.Nano.2012.11.006  1
2013 Donohue E, Thomas A, Maurer N, Manisali I, Zeisser-Labouebe M, Zisman N, Anderson HJ, Webb M, Bally M, Roberge M. Abstract B11: The early autophagy inhibitor verteporfin moderately enhances the antitumor activity of gemcitabine in a pancreatic ductal adenocarcinoma model Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-B11  0.56
2012 Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Roberge M, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496  0.4
2012 Khong A, Forestieri R, Williams DE, Patrick BO, Olmstead A, Svinti V, Schaeffer E, Jean F, Roberge M, Andersen RJ, Jan E. A daphnane diterpenoid isolated from Wikstroemia polyantha induces an inflammatory response and modulates miRNA activity. Plos One. 7: e39621. PMID 22761847 DOI: 10.1371/Journal.Pone.0039621  1
2012 Carr G, Williams DE, Ratnayake R, Bandara R, Wijesundara S, Tarling T, Balgi AD, Roberge M, Andersen RJ, Karunaratne V. Hortonones A to C, hydroazulenones from the genus Hortonia. Journal of Natural Products. 75: 1189-91. PMID 22626446 DOI: 10.1021/Np200927K  1
2012 Lam KK, Zheng X, Forestieri R, Balgi AD, Nodwell M, Vollett S, Anderson HJ, Andersen RJ, Av-Gay Y, Roberge M. Nitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of Mycobacterium tuberculosis. Plos Pathogens. 8: e1002691. PMID 22589723 DOI: 10.1371/Journal.Ppat.1002691  1
2012 Fonseca BD, Diering GH, Bidinosti MA, Dalal K, Alain T, Balgi AD, Forestieri R, Nodwell M, Rajadurai CV, Gunaratnam C, Tee AR, Duong F, Andersen RJ, Orlowski J, Numata M, ... ... Roberge M, et al. Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signaling. The Journal of Biological Chemistry. 287: 17530-45. PMID 22474287 DOI: 10.1074/Jbc.M112.359638  1
2012 Onishi I, Lin PJ, Numata Y, Austin P, Cipollone J, Roberge M, Roskelley CD, Numata M. Organellar (Na+, K+)/H+ exchanger NHE7 regulates cell adhesion, invasion and anchorage-independent growth of breast cancer MDA-MB-231 cells. Oncology Reports. 27: 311-7. PMID 22076128 DOI: 10.3892/or.2011.1542  1
2012 Rocha DD, Balgi A, Maia AI, Pessoa OD, Silveira ER, Costa-Lotufo LV, Roberge M, Pessoa C. Cell cycle arrest through inhibition of tubulin polymerization by withaphysalin F, a bioactive compound isolated from Acnistus arborescens. Investigational New Drugs. 30: 959-66. PMID 21416228 DOI: 10.1007/S10637-011-9649-X  1
2012 Kawamura E, Fielding A, Kannan N, Eaves C, Roberge M, Dedhar S. Abstract 3887: A screen for new cancer specific drugs that target centrosome clustering Cancer Research. 72: 3887-3887. DOI: 10.1158/1538-7445.Am2012-3887  0.32
2011 Balgi AD, Diering GH, Donohue E, Lam KK, Fonseca BD, Zimmerman C, Numata M, Roberge M. Regulation of mTORC1 signaling by pH. Plos One. 6: e21549. PMID 21738705 DOI: 10.1371/Journal.Pone.0021549  1
2011 Ramón-García S, Ng C, Anderson H, Chao JD, Zheng X, Pfeifer T, Av-Gay Y, Roberge M, Thompson CJ. Synergistic drug combinations for tuberculosis therapy identified by a novel high-throughput screen. Antimicrobial Agents and Chemotherapy. 55: 3861-9. PMID 21576426 DOI: 10.1128/Aac.00474-11  1
2011 Riffell JL, Jänicke RU, Roberge M. Caspase-3-dependent mitotic checkpoint inactivation by the small-molecule inducers of mitotic slippage SU6656 and geraldol. Molecular Cancer Therapeutics. 10: 839-49. PMID 21441410 DOI: 10.1158/1535-7163.Mct-10-0909  1
2011 Donohue E, Tovey A, Vogl AW, Arns S, Sternberg E, Young RN, Roberge M. Inhibition of autophagosome formation by the benzoporphyrin derivative verteporfin. The Journal of Biological Chemistry. 286: 7290-300. PMID 21193398 DOI: 10.1074/Jbc.M110.139915  1
2010 Gies E, Wilde I, Winget JM, Brack M, Rotblat B, Novoa CA, Balgi AD, Sorensen PH, Roberge M, Mayor T. Niclosamide prevents the formation of large ubiquitin-containing aggregates caused by proteasome inhibition. Plos One. 5: e14410. PMID 21203451 DOI: 10.1371/Journal.Pone.0014410  1
2010 Nodwell M, Zimmerman C, Roberge M, Andersen RJ. Synthetic analogues of the microtubule-stabilizing sponge alkaloid ceratamine A are more active than the natural product. Journal of Medicinal Chemistry. 53: 7843-51. PMID 20945907 DOI: 10.1021/Jm101012Q  1
2010 Austin P, Heller M, Williams DE, McIntosh LP, Vogl AW, Foster LJ, Andersen RJ, Roberge M, Roskelley CD. Release of membrane-bound vesicles and inhibition of tumor cell adhesion by the peptide Neopetrosiamide A. Plos One. 5: e10836. PMID 20520768 DOI: 10.1371/Journal.Pone.0010836  1
2010 Liu H, Boudreau MA, Zheng J, Whittal RM, Austin P, Roskelley CD, Roberge M, Andersen RJ, Vederas JC. Chemical synthesis and biological activity of the neopetrosiamides and their analogues: revision of disulfide bond connectivity. Journal of the American Chemical Society. 132: 1486-7. PMID 20073461 DOI: 10.1021/Ja9102925  1
2010 Carr G, Williams DE, Díaz-Marrero AR, Patrick BO, Bottriell H, Balgi AD, Donohue E, Roberge M, Andersen RJ. Bafilomycins produced in culture by Streptomyces spp. isolated from marine habitats are potent inhibitors of autophagy. Journal of Natural Products. 73: 422-7. PMID 20028134 DOI: 10.1021/Np900632R  1
2009 Balgi AD, Fonseca BD, Donohue E, Tsang TC, Lajoie P, Proud CG, Nabi IR, Roberge M. Screen for chemical modulators of autophagy reveals novel therapeutic inhibitors of mTORC1 signaling. Plos One. 4: e7124. PMID 19771169 DOI: 10.1371/Journal.Pone.0007124  1
2009 Riffell JL, Zimmerman C, Khong A, McHardy LM, Roberge M. Effects of chemical manipulation of mitotic arrest and slippage on cancer cell survival and proliferation. Cell Cycle (Georgetown, Tex.). 8: 3025-38. PMID 19713760 DOI: 10.4161/Cc.8.18.9623  1
2009 Balgi AD, Roberge M. Screening for chemical inhibitors of heterologous proteins expressed in yeast using a simple growth-restoration assay. Methods in Molecular Biology (Clifton, N.J.). 486: 125-37. PMID 19347620 DOI: 10.1007/978-1-60327-545-3_9  1
2009 Kemmer D, McHardy LM, Hoon S, Rebérioux D, Giaever G, Nislow C, Roskelley CD, Roberge M. Combining chemical genomics screens in yeast to reveal spectrum of effects of chemical inhibition of sphingolipid biosynthesis. Bmc Microbiology. 9: 9. PMID 19144191 DOI: 10.1186/1471-2180-9-9  1
2009 Nodwell M, Pereira A, Riffell JL, Zimmerman C, Patrick BO, Roberge M, Andersen RJ. Synthetic approaches to the microtubule-stabilizing sponge alkaloid ceratamine A and desbromo analogues. The Journal of Organic Chemistry. 74: 995-1006. PMID 19128042 DOI: 10.1021/Jo802322S  1
2008 Díaz-Marrero AR, Matainaho T, van Soest R, Roberge M, Andersen RJ. Scalarane-based metabolites isolated from the antimitotic extract of the marine sponge Hyrtios erectus. Natural Product Research. 22: 1304-9. PMID 19023786 DOI: 10.1080/14786410701824023  1
2008 Schriemer DC, Kemmer D, Roberge M. Design of phenotypic screens for bioactive chemicals and identification of their targets by genetic and proteomic approaches. Combinatorial Chemistry & High Throughput Screening. 11: 610-6. PMID 18795880 DOI: 10.2174/138620708785739934  1
2008 Roberge M. Defining drug targets in yeast haploinsufficiency screens: application to human translational pharmacology. Science Signaling. 1: pt5. PMID 18728306 DOI: 10.1126/Scisignal.134Pt5  1
2008 Williams DE, Davies J, Patrick BO, Bottriell H, Tarling T, Roberge M, Andersen RJ. Cladoniamides A-G, tryptophan-derived alkaloids produced in culture by Streptomyces uncialis. Organic Letters. 10: 3501-4. PMID 18646774 DOI: 10.1021/Ol801274C  1
2008 Keyzers RA, Daoust J, Davies-Coleman MT, Van Soest R, Balgi A, Donohue E, Roberge M, Andersen RJ. Autophagy-modulating aminosteroids isolated from the sponge Cliona celata. Organic Letters. 10: 2959-62. PMID 18553912 DOI: 10.1021/Ol800937U  1
2008 Nodwell M, Riffell JL, Roberge M, Andersen RJ. Synthesis of antimitotic analogs of the microtubule stabilizing sponge alkaloid ceratamine A. Organic Letters. 10: 1051-4. PMID 18278926 DOI: 10.1021/Ol7030284  1
2008 Hadaschik BA, Ettinger S, Sowery RD, Zoubeidi A, Andersen RJ, Roberge M, Gleave ME. Targeting prostate cancer with HTI-286, a synthetic analog of the marine sponge product hemiasterlin. International Journal of Cancer. Journal International Du Cancer. 122: 2368-76. PMID 18240145 DOI: 10.1002/Ijc.23406  1
2008 Sturgeon CM, Cinel B, Díaz-Marrero AR, McHardy LM, Ngo M, Andersen RJ, Roberge M. Abrogation of ionizing radiation-induced G2 checkpoint and inhibition of nuclear export by Cryptocarya pyrones. Cancer Chemotherapy and Pharmacology. 61: 407-13. PMID 17440726 DOI: 10.1007/S00280-007-0483-Y  1
2007 Williams DE, Keyzers RA, Warabi K, Desjardine K, Riffell JL, Roberge M, Andersen RJ. Spirastrellolides C to G: macrolides obtained from the marine sponge Spirastrella coccinea. The Journal of Organic Chemistry. 72: 9842-5. PMID 17988148 DOI: 10.1021/Jo7018174  1
2007 Williams DE, Sturgeon CM, Roberge M, Andersen RJ. Nigricanosides A and B, antimitotic glycolipids isolated from the green alga Avrainvillea nigricans collected in Dominica. Journal of the American Chemical Society. 129: 5822-3. PMID 17439220 DOI: 10.1021/Ja0715187  1
2007 Warabi K, Patrick BO, Austin P, Roskelley CD, Roberge M, Andersen RJ. Strongylophorine-26, an inhibitor of cancer cell Invasion: SAR revealed by synthesis of analogues. Journal of Natural Products. 70: 736-40. PMID 17407351 DOI: 10.1021/Np060481L  1
2007 Sturgeon CM, Roberge M. G2 checkpoint kinase inhibitors exert their radiosensitizing effects prior to the G2/M transition. Cell Cycle (Georgetown, Tex.). 6: 572-5. PMID 17351346  1
2007 Brastianos HC, Sturgeon CM, Roberge M, Andersen RJ. Inhibition of the G2 DNA damage checkpoint by oliveroline isolated from Duguetia odorata. Journal of Natural Products. 70: 287-8. PMID 17315964 DOI: 10.1021/Np060285E  1
2007 Warabi K, Williams DE, Patrick BO, Roberge M, Andersen RJ. Spirastrellolide B reveals the absolute configuration of the spirastrellolide macrolide core. Journal of the American Chemical Society. 129: 508-9. PMID 17227011 DOI: 10.1021/Ja068271I  1
2006 Rundle NT, Nelson J, Flory MR, Joseph J, Th'ng J, Aebersold R, Dasso M, Andersen RJ, Roberge M. An ent-kaurene that inhibits mitotic chromosome movement and binds the kinetochore protein ran-binding protein 2. Acs Chemical Biology. 1: 443-50. PMID 17168522 DOI: 10.1021/Cb600196W  1
2006 Pereira A, Vottero E, Roberge M, Mauk AG, Andersen RJ. Indoleamine 2,3-dioxygenase inhibitors from the Northeastern Pacific Marine Hydroid Garveia annulata. Journal of Natural Products. 69: 1496-9. PMID 17067170 DOI: 10.1021/Np060111X  1
2006 Diaz-Marrero AR, Austin P, Van Soest R, Matainaho T, Roskelley CD, Roberge M, Andersen RJ. Avinosol, a meroterpenoid-nucleoside conjugate with antiinvasion activity isolated from the marine sponge Dysidea sp. Organic Letters. 8: 3749-52. PMID 16898808 DOI: 10.1021/Ol061333P  1
2006 Sturgeon CM, Kemmer D, Anderson HJ, Roberge M. Yeast as a tool to uncover the cellular targets of drugs. Biotechnology Journal. 1: 289-98. PMID 16897709 DOI: 10.1002/biot.200500039  1
2006 Vottero E, Balgi A, Woods K, Tugendreich S, Melese T, Andersen RJ, Mauk AG, Roberge M. Inhibitors of human indoleamine 2,3-dioxygenase identified with a target-based screen in yeast. Biotechnology Journal. 1: 282-8. PMID 16897708 DOI: 10.1002/Biot.200600001  1
2006 Murphy S, Larrivée B, Pollet I, Craig KS, Williams DE, Huang XH, Abbott M, Wong F, Curtis C, Conrads TP, Veenstra T, Puri M, Hsiang Y, Roberge M, Andersen RJ, et al. Identification of sokotrasterol sulfate as a novel proangiogenic steroid. Circulation Research. 99: 257-65. PMID 16794189 DOI: 10.1161/01.Res.0000233316.17882.33  1
2006 Sturgeon CM, Knight ZA, Shokat KM, Roberge M. Effect of combined DNA repair inhibition and G2 checkpoint inhibition on cell cycle progression after DNA damage. Molecular Cancer Therapeutics. 5: 885-92. PMID 16648558 DOI: 10.1158/1535-7163.Mct-05-0358  0.88
2006 Vottero E, Mitchell DA, Page MJ, MacGillivray RT, Sadowski IJ, Roberge M, Mauk AG. Cytochrome b(5) is a major reductant in vivo of human indoleamine 2,3-dioxygenase expressed in yeast. Febs Letters. 580: 2265-8. PMID 16574111 DOI: 10.1016/J.Febslet.2006.03.034  1
2005 Sturgeon CM, Craig K, Brown C, Rundle NT, Andersen RJ, Roberge M. Modulation of the G2 cell cycle checkpoint by sesquiterpene lactones psilostachyins A and C isolated from the common ragweed Ambrosia artemisiifolia. Planta Medica. 71: 938-43. PMID 16254826 DOI: 10.1055/S-2005-873109  1
2005 Williams DE, Austin P, Diaz-Marrero AR, Soest RV, Matainaho T, Roskelley CD, Roberge M, Andersen RJ. Neopetrosiamides, peptides from the marine sponge Neopetrosia sp. that inhibit amoeboid invasion by human tumor cells. Organic Letters. 7: 4173-6. PMID 16146380 DOI: 10.1021/Ol051524C  1
2005 McHardy LM, Warabi K, Andersen RJ, Roskelley CD, Roberge M. Strongylophorine-26, a Rho-dependent inhibitor of tumor cell invasion that reduces actin stress fibers and induces nonpolarized lamellipodial extensions. Molecular Cancer Therapeutics. 4: 772-8. PMID 15897241 DOI: 10.1158/1535-7163.Mct-04-0310  1
2005 Karjala G, Chan Q, Manzo E, Andersen RJ, Roberge M. Ceratamines, structurally simple microtubule-stabilizing antimitotic agents with unusual cellular effects. Cancer Research. 65: 3040-3. PMID 15833830 DOI: 10.1158/0008-5472.Can-04-4369  1
2005 Williams DE, Patrick BO, Behrisch HW, Van Soest R, Roberge M, Andersen RJ. Dominicin, a cyclic octapeptide, and laughine, a bromopyrrole alkaloid, isolated from the Caribbean marine sponge Eurypon laughlini. Journal of Natural Products. 68: 327-30. PMID 15787430 DOI: 10.1021/Np049711R  0.56
2004 Williams DE, Patrick BO, Tahir A, Van Soest R, Roberge M, Andersen RJ. Boneratamides A-C, new sesquiterpenoids isolated from the marine sponge Axinyssa aplysinoides. Journal of Natural Products. 67: 1752-4. PMID 15497956 DOI: 10.1021/Np049798G  0.56
2004 Jiang X, Zhao B, Britton R, Lim LY, Leong D, Sanghera JS, Zhou BB, Piers E, Andersen RJ, Roberge M. Inhibition of Chk1 by the G2 DNA damage checkpoint inhibitor isogranulatimide. Molecular Cancer Therapeutics. 3: 1221-7. PMID 15486189  1
2004 Warabi K, McHardy LM, Matainaho L, Van Soest R, Roskelley CD, Roberge M, Andersen RJ. Strongylophorine-26, a new meroditerpenoid isolated from the marine sponge Petrosia (Strongylophora) corticata that exhibits anti-invasion activity. Journal of Natural Products. 67: 1387-9. PMID 15332859 DOI: 10.1021/Np0340246  0.56
2004 Williams DE, Lapawa M, Feng X, Tarling T, Roberge M, Andersen RJ. Spirastrellolide A: revised structure, progress toward the relative configuration, and inhibition of protein phosphatase 2A. Organic Letters. 6: 2607-10. PMID 15255702 DOI: 10.1021/Ol0490983  0.56
2004 Baetz K, McHardy L, Gable K, Tarling T, Rebérioux D, Bryan J, Andersen RJ, Dunn T, Hieter P, Roberge M. Yeast genome-wide drug-induced haploinsufficiency screen to determine drug mode of action. Proceedings of the National Academy of Sciences of the United States of America. 101: 4525-30. PMID 15070751 DOI: 10.1073/Pnas.0307122101  1
2004 McHardy LM, Sinotte R, Troussard A, Sheldon C, Church J, Williams DE, Andersen RJ, Dedhar S, Roberge M, Roskelley CD. The tumor invasion inhibitor dihydromotuporamine C activates RHO, remodels stress fibers and focal adhesions, and stimulates sodium-proton exchange. Cancer Research. 64: 1468-74. PMID 14973060 DOI: 10.1158/0008-5472.Can-03-2733  0.56
2004 Huang XH, van Soest R, Roberge M, Andersen RJ. Spiculoic acids A and B, new polyketides isolated from the Caribbean marine sponge Plakortis angulospiculatus. Organic Letters. 6: 75-8. PMID 14703354 DOI: 10.1021/Ol0361047  0.56
2003 Haggarty SJ, Koeller KM, Kau TR, Silver PA, Roberge M, Schreiber SL. Small molecule modulation of the human chromatid decatenation checkpoint. Chemistry & Biology. 10: 1267-79. PMID 14700634 DOI: 10.1016/J.Chembiol.2003.11.014  1
2003 Manzo E, van Soest R, Matainaho L, Roberge M, Andersen RJ. Ceratamines A and B, antimitotic heterocyclic alkaloids isolated from the marine sponge Pseudoceratina sp. collected in Papua New Guinea. Organic Letters. 5: 4591-4. PMID 14627391 DOI: 10.1021/Ol035721S  0.56
2003 Anderson HJ, Andersen RJ, Roberge M. Inhibitors of the G2 DNA damage checkpoint and their potential for cancer therapy. Progress in Cell Cycle Research. 5: 423-30. PMID 14593736  0.56
2003 Zhou BB, Anderson HJ, Roberge M. Targeting DNA checkpoint kinases in cancer therapy. Cancer Biology & Therapy. 2: S16-22. PMID 14508077 DOI: 10.4161/Cbt.200  0.4
2003 Britton R, Roberge M, Brown C, van Soest R, Andersen RJ. New okadaic acid analogues from the marine sponge Merriamum oxeato and their effect on mitosis. Journal of Natural Products. 66: 838-43. PMID 12828471 DOI: 10.1021/Np0300129  1
2003 Williams DE, Roberge M, Van Soest R, Andersen RJ. Spirastrellolide A, an antimitotic macrolide isolated from the Caribbean marine sponge Spirastrella coccinea. Journal of the American Chemical Society. 125: 5296-7. PMID 12720440 DOI: 10.1021/Ja0348602  0.56
2003 van Altena I, van Soest R, Roberge M, Andersen RJ. Trisphaerolide A, a novel polyketide from the Dominican sponge Erylus trisphaerus. Journal of Natural Products. 66: 561-3. PMID 12713417 DOI: 10.1021/Np0205147  0.56
2003 Nieman JA, Coleman JE, Wallace DJ, Piers E, Lim LY, Roberge M, Andersen RJ. Synthesis and antimitotic/cytotoxic activity of hemiasterlin analogues. Journal of Natural Products. 66: 183-99. PMID 12608848 DOI: 10.1021/Np020375T  1
2002 Taglialatela-Scafati O, Deo-Jangra U, Campbell M, Roberge M, Andersen RJ. Diterpenoids from cultured Erythropodium caribaeorum. Organic Letters. 4: 4085-8. PMID 12423092 DOI: 10.1021/Ol026831M  0.56
2002 Williams DE, Craig KS, Patrick B, McHardy LM, van Soest R, Roberge M, Andersen RJ. Motuporamines, anti-invasion and anti-angiogenic alkaloids from the marine sponge Xestospongia exigua (Kirkpatrick): isolation, structure elucidation, analogue synthesis, and conformational analysis. The Journal of Organic Chemistry. 67: 245-58. PMID 11777468 DOI: 10.1021/Jo016101C  1
2001 Rundle NT, Xu L, Andersen RJ, Roberge M. G2 DNA damage checkpoint inhibition and antimitotic activity of 13-hydroxy-15-oxozoapatlin. The Journal of Biological Chemistry. 276: 48231-6. PMID 11572854 DOI: 10.1074/Jbc.M103990200  1
2001 Britton R, De Silva ED, Bigg CM, McHardy LM, Roberge M, Andersen RJ. Synthetic transformations of eleutherobin reveal new features of its microtubule-stabilizing pharmacophore [20] Journal of the American Chemical Society. 123: 8632-8633. PMID 11525686 DOI: 10.1021/Ja016459Q  1
2001 Curman D, Cinel B, Williams DE, Rundle N, Block WD, Goodarzi AA, Hutchins JR, Clarke PR, Zhou BB, Lees-Miller SP, Andersen RJ, Roberge M. Inhibition of the G2 DNA damage checkpoint and of protein kinases Chk1 and Chk2 by the marine sponge alkaloid debromohymenialdisine. The Journal of Biological Chemistry. 276: 17914-9. PMID 11279124 DOI: 10.1074/Jbc.M100728200  1
2001 Britton R, Roberge M, Berisch H, Andersen RJ. Antimitotic diterpenoids from Erythropodium caribaeorum: Isolation artifacts and putative biosynthetic intermediates Tetrahedron Letters. 42: 2953-2956. DOI: 10.1016/S0040-4039(01)00347-1  1
2000 Cinel B, Roberge M, Behrisch H, van Ofwegen L, Castro CB, Andersen RJ. Antimitotic diterpenes from Erythropodium caribaeorum test pharmacophore models for microtubule stabilization. Organic Letters. 2: 257-60. PMID 10814296 DOI: 10.1021/Ol9912027  1
2000 Jiang X, Lim LY, Daly JW, Li AH, Jacobson KA, Roberge M. Structure-activity relationships for G2 checkpoint inhibition by caffeine analogs. International Journal of Oncology. 16: 971-8. PMID 10762633 DOI: 10.3892/Ijo.16.5.971  1
2000 Sauvé DM, Anderson HJ, Ray JM, James WM, Roberge M. Phosphorylation-induced rearrangement of the histone H3 NH2-terminal domain during mitotic chromosome condensation Journal of Cell Biology. 145: 225-235. PMID 10209020 DOI: 10.1083/Jcb.145.2.225  1
2000 Cinel B, Patrick BO, Roberge M, Andersen RJ. Solid-state and solution conformations of eleutherobin obtained from X- ray diffraction analysis and solution NOE data Tetrahedron Letters. 41: 2811-2815. DOI: 10.1016/S0040-4039(00)00269-0  1
1998 Juan G, Traganos F, James WM, Ray JM, Roberge M, Sauve DM, Anderson H, Darzynkiewicz Z. Histone H3 phosphorylation and expression of cyclins A and B1 measured in individual cells during their progression through G2 and mitosis Cytometry. 32: 71-77. PMID 9627219 DOI: 10.1002/(Sici)1097-0320(19980601)32:2<71::Aid-Cyto1>3.0.Co;2-H  1
1998 Anderson HJ, Jong Gd, Vincent I, Roberge M. Flow cytometry of mitotic cells. Experimental Cell Research. 238: 498-502. PMID 9473359 DOI: 10.1006/Excr.1997.3862  0.4
1998 Berlmck RGS, Britton R, Piers E, Lim L, Roberge M, Rosana Moreira Da Rocha, Andersen RJ. Granulatimide and isogranulatimide, aromatic alkaloids with G2 checkpoint inhibition activity isolated from the Brazilian ascidian Didemnum granulatum: Structure elucidation and synthesis Journal of Organic Chemistry. 63: 9850-9856. DOI: 10.1021/Jo981607P  1
1997 Anderson HJ, Coleman JE, Andersen RJ, Roberge M. Cytotoxic peptides hemiasterlin, hemiasterlin A and hemiasterlin B induce mitotic arrest and abnormal spindle formation. Cancer Chemotherapy and Pharmacology. 39: 223-6. PMID 8996524 DOI: 10.1007/S002800050564  1
1995 Guo XW, Th'ng JP, Swank RA, Anderson HJ, Tudan C, Bradbury EM, Roberge M. Chromosome condensation induced by fostriecin does not require p34cdc2 kinase activity and histone H1 hyperphosphorylation, but is associated with enhanced histone H2A and H3 phosphorylation. The Embo Journal. 14: 976-85. PMID 7889943  1
1992 O'Neill TE, Roberge M, Bradbury EM. Nucleosome arrays inhibit both initiation and elongation of transcripts by bacteriophage T7 RNA polymerase. Journal of Molecular Biology. 223: 67-78. PMID 1731087 DOI: 10.1016/0022-2836(92)90716-W  1
1992 Anderson HJ, Roberge M. DNA topoisomerase II: A review of its involvement in chromosome structure, DNA replication, transcription and mitosis Cell Biology International Reports. 16: 717-724. PMID 1332830 DOI: 10.1016/S0309-1651(05)80016-5  0.4
1991 Roberge M, O'Neill TE, Bradbury EM. Inhibition of 5S RNA transcription in vitro by nucleosome cores with low or high levels of histone acetylation Febs Letters. 288: 215-218. PMID 1879554 DOI: 10.1016/0014-5793(91)81037-9  1
1990 Roberge M, Th'ng J, Hamaguchi J, Bradbury EM. The topoisomerase II inhibitor VM-26 induces marked changes in histone H1 kinase activity, histones H1 and H3 phosphorylation, and chromosome condensation in G2 phase and mitotic BHK cells Journal of Cell Biology. 111: 1753-1762. PMID 2172257  1
1988 Roberge M, Dahmus ME, Bradbury EM. Chromosomal loop/nuclear matrix organization of transcriptionally active and inactive RNA polymerases in HeLa nuclei Journal of Molecular Biology. 201: 545-555. PMID 3418709 DOI: 10.1016/0022-2836(88)90636-5  1
1988 Roberge M, Bradbury EM. RNA contacts the two large polymerase subunits and a 52-kDa polypeptide in nucleolar RNA polymerase I transcribing complexes Journal of Biological Chemistry. 263: 18553-18557. PMID 3192549  1
1986 Schaller HC, Roberge M, Zachmann B, Hoffmeister S, Schilling E, Bodenmüller H. The head activator is released from regenerating Hydra bound to a carrier molecule. The Embo Journal. 5: 1821-4. PMID 16453697  0.01
1985 Bodenmüller H, Roberge M. The head activator: discovery, characterisation, immunoassays and biological properties in mammals. Biochimica Et Biophysica Acta. 825: 261-7. PMID 2410027 DOI: 10.1016/0167-4781(85)90013-2  0.01
1984 Roberge M, Escher E, Schaller HC, Bodenmüller H. The hydra head activator in human blood circulation. Degradation of the synthetic peptide by plasma angiotensin-converting enzyme. Febs Letters. 173: 307-13. PMID 6086405 DOI: 10.1016/0014-5793(84)80796-6  0.01
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