Eileen M. Denovan-Wright - Publications

Affiliations: 
Dalhousie University, Halifax, Nova Scotia, Canada 
Area:
Biochemistry

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Laprairie RB, Bagher AM, Rourke JL, Zrein A, Cairns EA, Kelly MEM, Sinal CJ, Kulkarni PM, Thakur GA, Denovan-Wright EM. Positive allosteric modulation of the type 1 cannabinoid receptor reduces the signs and symptoms of Huntington's disease in the R6/2 mouse model. Neuropharmacology. PMID 30940536 DOI: 10.1016/J.Neuropharm.2019.03.033  0.31
2018 Laprairie RB, Petr GT, Sun Y, Fischer KD, Denovan-Wright EM, Rosenberg PA. Huntington's disease pattern of transcriptional dysregulation in the absence of mutant huntingtin is produced by knockout of neuronal GLT-1. Neurochemistry International. PMID 29709465 DOI: 10.1016/J.Neuint.2018.04.015  0.409
2017 Laprairie RB, Denovan-Wright EM, Wright JM. Differential regulation of the duplicated fabp7, fabp10 and fabp11 genes of zebrafish by peroxisome proliferator activated receptors. Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. PMID 28844908 DOI: 10.1016/J.Cbpb.2017.08.003  0.573
2017 Laprairie RB, Kulkarni PM, Deschamps JR, Kelly ME, Janero DR, Cascio MG, Stevenson LA, Pertwee RG, Kenakin T, Denovan-Wright EM, Thakur GA. Enantio-specific Allosteric Modulation of Cannabinoid 1 Receptor. Acs Chemical Neuroscience. PMID 28103441 DOI: 10.1021/Acschemneuro.6B00310  0.318
2016 Laprairie RB, Denovan-Wright EM, Wright JM. Subfunctionalization of peroxisome proliferator response elements accounts for retention of duplicated fabp1 genes in zebrafish. Bmc Evolutionary Biology. 16: 147. PMID 27421266 DOI: 10.1186/S12862-016-0717-X  0.526
2016 Laprairie RB, Denovan-Wright EM, Wright JM. Divergent evolution of cis-acting peroxisome proliferator-activated receptor elements that differentially control the tandemly duplicated fatty acid-binding protein genes, fabp1b.1 and fabp1b.2, in zebrafish. Genome / National Research Council Canada = Genome / Conseil National De Recherches Canada. 1-10. PMID 27228313 DOI: 10.1139/Gen-2016-0033  0.528
2015 Kulkarni PM, Kulkarni AR, Korde A, Tichkule RB, Laprairie RB, Denovan-Wright EM, Zhou H, Janero DR, Zvonok N, Makriyannis A, Cascio MG, Pertwee RG, Thakur GA. Novel Electrophilic and Photoaffinity Covalent Probes for Mapping the Cannabinoid 1 Receptor Allosteric Site(s). Journal of Medicinal Chemistry. PMID 26529344 DOI: 10.1021/Acs.Jmedchem.5B01303  0.31
2014 Laprairie RB, Warford JR, Hutchings S, Robertson GS, Kelly ME, Denovan-Wright EM. The cytokine and endocannabinoid systems are co-regulated by NF-κB p65/RelA in cell culture and transgenic mouse models of Huntington's disease and in striatal tissue from Huntington's disease patients. Journal of Neuroimmunology. 267: 61-72. PMID 24360910 DOI: 10.1016/J.Jneuroim.2013.12.008  0.34
2013 Bagher AM, Laprairie RB, Kelly ME, Denovan-Wright EM. Co-expression of the human cannabinoid receptor coding region splice variants (hCB₁) affects the function of hCB₁ receptor complexes. European Journal of Pharmacology. 721: 341-54. PMID 24091169 DOI: 10.1016/J.Ejphar.2013.09.002  0.327
2013 Laprairie RB, Kelly ME, Denovan-Wright EM. Cannabinoids increase type 1 cannabinoid receptor expression in a cell culture model of striatal neurons: implications for Huntington's disease. Neuropharmacology. 72: 47-57. PMID 23602984 DOI: 10.1016/J.Neuropharm.2013.04.006  0.34
2012 Laprairie RB, Kelly MEM, Denovan-Wright EM. The dynamic nature of type 1 cannabinoid receptor (CB1) gene transcription British Journal of Pharmacology. 167: 1583-1595. PMID 22924606 DOI: 10.1111/J.1476-5381.2012.02175.X  0.512
2012 Hogel M, Laprairie RB, Denovan-Wright EM. Promoters are differentially sensitive to N-terminal mutant huntingtin-mediated transcriptional repression. Plos One. 7: e41152. PMID 22815947 DOI: 10.1371/Journal.Pone.0041152  0.372
2012 Venkatachalam AB, Lall SP, Denovan-Wright EM, Wright JM. Tissue-specific differential induction of duplicated fatty acid-binding protein genes by the peroxisome proliferator, clofibrate, in zebrafish (Danio rerio). Bmc Evolutionary Biology. 12: 112. PMID 22776158 DOI: 10.1186/1471-2148-12-112  0.593
2011 Denovan-Wright EM, Currie RW. The silence of the limbs. Cardiovascular Research. 92: 185-6. PMID 21921081 DOI: 10.1093/Cvr/Cvr248  0.309
2011 Rising AC, Xu J, Carlson A, Napoli VV, Denovan-Wright EM, Mandel RJ. Longitudinal behavioral, cross-sectional transcriptional and histopathological characterization of a knock-in mouse model of Huntington's disease with 140 CAG repeats. Experimental Neurology. 228: 173-82. PMID 21192926 DOI: 10.1016/J.Expneurol.2010.12.017  0.341
2009 Karanth S, Denovan-Wright EM, Thisse C, Thisse B, Wright JM. Tandem duplication of the fabp1b gene and subsequent divergence of the tissue-specific distribution of fabp1b.1 and fabp1b.2 transcripts in zebrafish (Danio rerio). Genome / National Research Council Canada = GéNome / Conseil National De Recherches Canada. 52: 985-92. PMID 19953126 DOI: 10.1139/G09-071  0.509
2009 Karanth S, Lall SP, Denovan-Wright EM, Wright JM. Differential transcriptional modulation of duplicated fatty acid-binding protein genes by dietary fatty acids in zebrafish (Danio rerio): evidence for subfunctionalization or neofunctionalization of duplicated genes. Bmc Evolutionary Biology. 9: 219. PMID 19725974 DOI: 10.1186/1471-2148-9-219  0.508
2008 Alves-Costa FA, Denovan-Wright EM, Thisse C, Thisse B, Wright JM. Spatio-temporal distribution of fatty acid-binding protein 6 (fabp6) gene transcripts in the developing and adult zebrafish (Danio rerio). The Febs Journal. 275: 3325-34. PMID 18492067 DOI: 10.1111/j.1742-4658.2008.06480.x  0.542
2008 Karanth S, Denovan-Wright EM, Thisse C, Thisse B, Wright JM. The evolutionary relationship between the duplicated copies of the zebrafish fabp11 gene and the tetrapod FABP4, FABP5, FABP8 and FABP9 genes. The Febs Journal. 275: 3031-40. PMID 18445037 DOI: 10.1111/J.1742-4658.2008.06455.X  0.62
2008 Denovan-Wright EM, Attis M, Rodriguez-Lebron E, Mandel RJ. Sustained striatal ciliary neurotrophic factor expression negatively affects behavior and gene expression in normal and R6/1 mice. Journal of Neuroscience Research. 86: 1748-57. PMID 18293418 DOI: 10.1002/Jnr.21636  0.328
2008 Denovan-Wright EM, Rodriguez-Lebron E, Lewin AS, Mandel RJ. Unexpected off-targeting effects of anti-huntingtin ribozymes and siRNA in vivo. Neurobiology of Disease. 29: 446-55. PMID 18166484 DOI: 10.1016/J.Nbd.2007.11.003  0.434
2007 Liu RZ, Saxena V, Sharma MK, Thisse C, Thisse B, Denovan-Wright EM, Wright JM. The fabp4 gene of zebrafish (Danio rerio)--genomic homology with the mammalian FABP4 and divergence from the zebrafish fabp3 in developmental expression. The Febs Journal. 274: 1621-33. PMID 17480210 DOI: 10.1111/J.1742-4658.2007.05711.X  0.798
2007 Gilby KL, Denovan-Wright EM. Analysis of gene expression in the brain using differential display Handbook of Neurochemistry and Molecular Neurobiology: Practical Neurochemistry Methods. 371-385. DOI: 10.1007/978-0-387-30401-4_17  0.345
2006 Sharma MK, Liu RZ, Thisse C, Thisse B, Denovan-Wright EM, Wright JM. Hierarchical subfunctionalization of fabp1a, fabp1b and fabp10 tissue-specific expression may account for retention of these duplicated genes in the zebrafish (Danio rerio) genome. The Febs Journal. 273: 3216-29. PMID 16857010 DOI: 10.1111/J.1742-4658.2006.05330.X  0.803
2006 Gomez GT, Hu H, McCaw EA, Denovan-Wright EM. Brain-specific factors in combination with mutant huntingtin induce gene-specific transcriptional dysregulation. Molecular and Cellular Neurosciences. 31: 661-75. PMID 16446101 DOI: 10.1016/J.Mcn.2005.12.004  0.411
2005 Rodriguez-Lebron E, Denovan-Wright EM, Nash K, Lewin AS, Mandel RJ. Intrastriatal rAAV-mediated delivery of anti-huntingtin shRNAs induces partial reversal of disease progression in R6/1 Huntington's disease transgenic mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 618-33. PMID 16019264 DOI: 10.1016/J.Ymthe.2005.05.006  0.353
2005 Liu RZ, Sharma MK, Sun Q, Thisse C, Thisse B, Denovan-Wright EM, Wright JM. Retention of the duplicated cellular retinoic acid-binding protein 1 genes (crabp1a and crabp1b) in the zebrafish genome by subfunctionalization of tissue-specific expression. The Febs Journal. 272: 3561-71. PMID 16008556 DOI: 10.1111/J.1742-4658.2005.04775.X  0.809
2005 Sharma MK, Saxena V, Liu RZ, Thisse C, Thisse B, Denovan-Wright EM, Wright JM. Differential expression of the duplicated cellular retinoic acid-binding protein 2 genes (crabp2a and crabp2b) during zebrafish embryonic development. Gene Expression Patterns : Gep. 5: 371-9. PMID 15661643 DOI: 10.1016/J.Modgep.2004.09.010  0.797
2005 Liu RZ, Sun Q, Thisse C, Thisse B, Wright JM, Denovan-Wright EM. The cellular retinol-binding protein genes are duplicated and differentially transcribed in the developing and adult zebrafish (Danio rerio). Molecular Biology and Evolution. 22: 469-77. PMID 15509725 DOI: 10.1093/Molbev/Msi030  0.807
2005 Rodriguez E, Denovan-Wright E, Lewin AS, Mandel RJ. 954. Demonstration of In Vivo Off-Targeting Using rAAV-Delivered Ribozymes and shRNA Molecules in a Mouse Model of Huntington's Disease Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.497  0.473
2005 Rodriguez E, Denovan-Wright E, Mandel RJ. 952. Effects of rAAV-BDNF Expression in the Striatum of the R6/1 Mouse Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.495  0.342
2005 Rodriguez E, Denovan-Wright E, Nash K, Lewin AS, Mandel RJ. 53. Post-Transcriptional Suppression of Striatal Mutant Huntingtin Leads to Mild Phenotypic Improvements in the R6/1 Mouse Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.081  0.379
2004 Hu H, McCaw EA, Hebb AL, Gomez GT, Denovan-Wright EM. Mutant huntingtin affects the rate of transcription of striatum-specific isoforms of phosphodiesterase 10A. The European Journal of Neuroscience. 20: 3351-63. PMID 15610167 DOI: 10.1111/j.1460-9568.2004.03796.x  0.397
2004 McCaw EA, Hu H, Gomez GT, Hebb AL, Kelly ME, Denovan-Wright EM. Structure, expression and regulation of the cannabinoid receptor gene (CB1) in Huntington's disease transgenic mice. European Journal of Biochemistry / Febs. 271: 4909-20. PMID 15606779 DOI: 10.1111/j.1432-1033.2004.04460.x  0.337
2004 Sharma MK, Denovan-Wright EM, Degrave A, Thisse C, Thisse B, Wright JM. Sequence, linkage mapping and early developmental expression of the intestinal-type fatty acid-binding protein gene (fabp2) from zebrafish (Danio rerio). Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. 138: 391-8. PMID 15325340 DOI: 10.1016/J.Cbpc.2004.05.009  0.601
2004 Liu RZ, Denovan-Wright EM, Degrave A, Thisse C, Thisse B, Wright JM. Differential expression of duplicated genes for brain-type fatty acid-binding proteins (fabp7a and fabp7b) during early development of the CNS in zebrafish (Danio rerio). Gene Expression Patterns : Gep. 4: 379-87. PMID 15183304 DOI: 10.1016/J.Modgep.2004.01.010  0.808
2004 Hebb AL, Robertson HA, Denovan-Wright EM. Striatal phosphodiesterase mRNA and protein levels are reduced in Huntington's disease transgenic mice prior to the onset of motor symptoms. Neuroscience. 123: 967-81. PMID 14751289 DOI: 10.1016/J.Neuroscience.2003.11.009  0.352
2004 Liu RZ, Denovan-Wright EM, Degrave A, Thisse C, Thisse B, Wright JM. Spatio-temporal distribution of cellular retinol-binding protein gene transcripts (CRBPI and CRBPII) in the developing and adult zebrafish (Danio rerio). European Journal of Biochemistry / Febs. 271: 339-48. PMID 14717701 DOI: 10.1046/J.1432-1033.2003.03932.X  0.81
2003 Liu RZ, Denovan-Wright EM, Wright JM. Structure, linkage mapping and expression of the heart-type fatty acid-binding protein gene (fabp3 ) from zebrafish (Danio rerio). European Journal of Biochemistry / Febs. 270: 3223-34. PMID 12869198 DOI: 10.1046/J.1432-1033.2003.03705.X  0.811
2003 Sharma MK, Denovan-Wright EM, Boudreau ME, Wright JM. A cellular retinoic acid-binding protein from zebrafish (Danio rerio): cDNA sequence, phylogenetic analysis, mRNA expression, and gene linkage mapping. Gene. 311: 119-28. PMID 12853146 DOI: 10.1016/S0378-1119(03)00580-8  0.594
2003 Bertolesi GE, Jollimore CAB, Shi C, Elbaum L, Denovan-Wright EM, Barnes S, Kelly MEM. Regulation of α1G T-type calcium channel gene (CACNA1 G) expression during neuronal differentiation European Journal of Neuroscience. 17: 1802-1810. PMID 12752779 DOI: 10.1046/J.1460-9568.2003.02618.X  0.412
2003 Liu RZ, Denovan-Wright EM, Wright JM. Structure, mRNA expression and linkage mapping of the brain-type fatty acid-binding protein gene (FABP7) from zebrafish (Danio rerio). European Journal of Biochemistry / Febs. 270: 715-25. PMID 12581211 DOI: 10.1046/J.1432-1033.2003.03432.X  0.782
2002 Cameron MC, Denovan-Wright EM, Sharma MK, Wright JM. Cellular retinol-binding protein type II (CRBPII) in adult zebrafish (Danio rerio). cDNA sequence, tissue-specific expression and gene linkage analysis. European Journal of Biochemistry / Febs. 269: 4685-92. PMID 12230582 DOI: 10.1046/J.1432-1033.2002.03170.X  0.581
2000 Denovan-Wright EM, Pierce M, Sharma MK, Wright JM. cDNA sequence and tissue-specific expression of a basic liver-type fatty acid binding protein in adult zebrafish (Danio rerio). Biochimica Et Biophysica Acta. 1492: 227-232. PMID 11004494 DOI: 10.1016/S0167-4781(00)00102-0  0.526
2000 Denovan-Wright EM, Pierce M, Wright JM. Nucleotide sequence of cDNA clones coding for a brain-type fatty acid binding protein and its tissue-specific expression in adult zebrafish (Danio rerio). Biochimica Et Biophysica Acta. 1492: 221-226. PMID 11004493 DOI: 10.1016/S0167-4781(00)00075-0  0.531
2000 Pierce M, Wang Y, Denovan-Wright EM, Wright JM. Nucleotide sequence of a cDNA clone coding for an intestinal-type fatty acid binding protein and its tissue-specific expression in zebrafish (Danio rerio). Biochimica Et Biophysica Acta. 1490: 175-83. PMID 10786634 DOI: 10.1016/S0167-4781(99)00229-8  0.556
2000 Denovan-Wright EM, Ferrier GR, Robertson HA, Howlett SE. Increased expression of the gene for alpha-interferon-inducible protein in cardiomyopathic hamster heart. Biochemical and Biophysical Research Communications. 267: 103-8. PMID 10623582 DOI: 10.1006/Bbrc.1999.1938  0.38
2000 Denovan-Wright EM, Hamilton LC, Robertson HA. Differential gene expression in the striatum of transgenic Huntington's disease mice Biochemical Society Transactions. 28: A304-A304. DOI: 10.1042/Bst028A304A  0.381
2000 Wright JM, Denovan-Wright EM, Pierce M, Wang Y, Sharma MK, Anopuechi V, Liu R. Sequence of fatty acid binding proteins and their tissue-specific expression in adult zebrafish (Danio rerio) Biochemical Society Transactions. 28: A238-A238. DOI: 10.1042/Bst028A238C  0.747
1999 Hebb MO, Denovan-Wright EM, Robertson HA. Expression of the Huntington's disease gene is regulated in astrocytes in the arcuate nucleus of the hypothalamus of postpartum rats. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 13: 1099-106. PMID 10336893 DOI: 10.1096/Fasebj.13.9.1099  0.462
1998 Denovan-Wright EM, Newton RA, Armstrong JN, Babity JM, Robertson HA. Acute administration of cocaine, but not amphetamine, increases the level of synaptotagmin IV mRNA in the dorsal striatum of rat. Brain Research. Molecular Brain Research. 55: 350-4. PMID 9582453 DOI: 10.1016/S0169-328X(98)00042-4  0.351
1998 Denovan-Wright EM, Nedelcu AM, Lee RW. Complete sequence of the mitochondrial DNA of Chlamydomonas eugametos. Plant Molecular Biology. 36: 285-95. PMID 9484440 DOI: 10.1023/A:1005995718091  0.428
1996 Denovan-Wright EM, Ramsey NB, McCormick CJ, Lazier CB, Wright JM. Nucleotide sequence of transferrin cDNAs and tissue-specific of the transferrin gene in Atlantic cod (Gadus morhua). Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. 113: 269-73. PMID 8653583 DOI: 10.1016/0305-0491(95)02023-3  0.525
1996 Denovan-Wright EM, Sankoff D, Spencer DF, Lee RW. Evolution of fragmented mitochondrial ribosomal RNA genes in Chlamydomonas. Journal of Molecular Evolution. 42: 382-91. PMID 8642607 DOI: 10.1007/Bf02498632  0.42
1994 Denovan-Wright EM, Lee RW. Comparative structure and genomic organization of the discontinuous mitochondrial ribosomal RNA genes of Chlamydomonas eugametos and Chlamydomonas reinhardtii. Journal of Molecular Biology. 241: 298-311. PMID 7520083 DOI: 10.1006/Jmbi.1994.1505  0.399
1992 Denovan-Wright EM, Lee RW. Comparative analysis of the mitochondrial genomes of Chlamydomonas eugametos and Chlamydomonas moewusii. Current Genetics. 21: 197-202. PMID 1563044 DOI: 10.1007/Bf00336841  0.31
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