Year |
Citation |
Score |
2019 |
Zhang WF, Li T, Lin SX. Meta-Analysis of steroid-converting enzymes and related receptors in prostate cancer suggesting novel combined therapies. The Journal of Steroid Biochemistry and Molecular Biology. 105559. PMID 31783154 DOI: 10.1016/j.jsbmb.2019.105559 |
0.36 |
|
2019 |
Liu WJ, Zhao G, Zhang CY, Yang CQ, Zeng XB, Li J, Zhu K, Zhao SQ, Lu HM, Yin DC, Lin SX. Comparison of the roles of estrogens and androgens in breast cancer and prostate cancer. Journal of Cellular Biochemistry. PMID 31693255 DOI: 10.1002/jcb.29515 |
0.48 |
|
2019 |
Zhang CY, Calvo EL, Yang CQ, Liu J, Sang XY, Lin SX. Transcriptome of 17β-hydroxysteroid dehydrogenase type 2 plays both hormone-dependent and hormone-independent roles in MCF-7 breast cancer cells. The Journal of Steroid Biochemistry and Molecular Biology. 105471. PMID 31513846 DOI: 10.1016/j.jsbmb.2019.105471 |
0.48 |
|
2019 |
Tchernof A, Lin SX, Luu-The V, Simard J. The Passing of Dr. Fernand Labrie (1937-2019): The legacy of excellence in science. The Journal of Steroid Biochemistry and Molecular Biology. PMID 30779933 DOI: 10.1016/j.jsbmb.2019.02.005 |
0.32 |
|
2019 |
Li T, Stephen P, Zhu DW, Shi R, Lin SX. Crystal structures of human 17β-hydroxysteroid dehydrogenase type 1 complexed with estrone and NADP reveal the mechanism of substrate inhibition. The Febs Journal. PMID 30768851 DOI: 10.1111/febs.14784 |
0.52 |
|
2019 |
Ran Q, Xiang Y, Stephen P, Wu C, Li T, Lin SX, Li Z. CRIF1-CDK2 Interface Inhibitors: An Unprecedented Strategy for Modulation of Cell Radiosensitivity. Journal of the American Chemical Society. PMID 30653304 DOI: 10.1021/jacs.8b10207 |
0.36 |
|
2019 |
Li T, Zhang W, Hao J, Sun M, Lin SX. Cold-active extracellular lipase: Expression in Sf9 insect cells, purification, and catalysis. Biotechnology Reports (Amsterdam, Netherlands). 21: e00295. PMID 30568889 DOI: 10.1016/j.btre.2018.e00295 |
0.36 |
|
2018 |
Li T, Maltais R, Poirier D, Lin SX. Combined Biophysical Chemistry Reveals the Finding of a New Covalent Inhibitor with a Low-Reactive Alkyl Halide. The Journal of Physical Chemistry Letters. PMID 30148957 DOI: 10.1021/acs.jpclett.8b02225 |
0.36 |
|
2018 |
Hsiao YF, Tsai PJ, Chen HS, Lin SX, Hung CC, Lee CH, Chen YH, Chen YF, Yu IA, Chen YC. Highly Efficient Coherent Optical Memory Based on Electromagnetically Induced Transparency. Physical Review Letters. 120: 183602. PMID 29775362 DOI: 10.1103/PhysRevLett.120.183602 |
0.72 |
|
2018 |
Stephen P, Ye S, Zhou M, Song J, Zhang R, Wang ED, Giegé R, Lin SX. Structure of Escherichia coli arginyl-tRNA synthetase in complex with tRNA: pivotal role of the D-loop. Journal of Molecular Biology. PMID 29678554 DOI: 10.1016/j.jmb.2018.04.011 |
0.6 |
|
2016 |
Aka JA, Calvo EL, Lin SX. Genomic data on breast cancer transcript profile modulation by 17beta-hydroxysteroid dehydrogenase type 1 and 17-beta-estradiol. Data in Brief. 9: 1000-1012. PMID 27900352 DOI: 10.1016/j.dib.2016.11.010 |
0.44 |
|
2016 |
Aka JA, Calvo EL, Lin SX. Estradiol-independent modulation of breast cancer transcript profile by 17beta-hydroxysteroid dehydrogenase type 1. Molecular and Cellular Endocrinology. PMID 27544780 DOI: 10.1016/j.mce.2016.08.026 |
0.44 |
|
2016 |
He W, Gauri M, Li T, Wang R, Lin SX. Current knowledge of the multifunctional 17β-hydroxysteroid dehydrogenase type 1 (HSD17B1). Gene. PMID 27102893 DOI: 10.1016/j.gene.2016.04.031 |
0.36 |
|
2016 |
Zhang B, Hu XJ, Wang XQ, Thériault JF, Zhu DW, Shang P, Labrie F, Lin SX. Human 3α-HSD3: Structural clues of 5α-DHT reverse binding and enzyme down-regulation decreasing MCF7 cell growth. The Biochemical Journal. PMID 26929402 DOI: 10.1042/BCJ20160083 |
0.48 |
|
2015 |
Zhang CY, Wang WQ, Chen J, Lin SX. Reductive 17beta-hydroxysteroid dehydrogenases which synthesize estradiol and inactivate dihydrotestosterone constitute major and concerted players in ER+ breast cancer cells. The Journal of Steroid Biochemistry and Molecular Biology. 150: 24-34. PMID 25257817 DOI: 10.1016/j.jsbmb.2014.09.017 |
0.44 |
|
2014 |
Zhang B, Zhu DW, Hu XJ, Zhou M, Shang P, Lin SX. Human 3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3): the V54L mutation restricting the steroid alternative binding and enhancing the 20α-HSD activity. The Journal of Steroid Biochemistry and Molecular Biology. 141: 135-43. PMID 24434280 DOI: 10.1016/j.jsbmb.2014.01.003 |
0.6 |
|
2013 |
Shi R, Chen ZY, Zhu DW, Li C, Shan Y, Xu G, Lin SX. Crystal structures of human muscle fructose-1,6-bisphosphatase: novel quaternary states, enhanced AMP affinity, and allosteric signal transmission pathway. Plos One. 8: e71242. PMID 24086250 DOI: 10.1371/journal.pone.0071242 |
0.52 |
|
2013 |
Lambert AA, Azzi A, Lin SX, Allaire G, St-Gelais KP, Tremblay MJ, Gilbert C. Dendritic cell immunoreceptor is a new target for anti-AIDS drug development: identification of DCIR/HIV-1 inhibitors. Plos One. 8: e67873. PMID 23874461 DOI: 10.1371/journal.pone.0067873 |
0.48 |
|
2012 |
Zhang CY, Chen J, Yin DC, Lin SX. The contribution of 17beta-hydroxysteroid dehydrogenase type 1 to the estradiol-estrone ratio in estrogen-sensitive breast cancer cells. Plos One. 7: e29835. PMID 22253796 DOI: 10.1371/journal.pone.0029835 |
0.48 |
|
2011 |
Zhang SC, Sun M, Li T, Wang QH, Hao JH, Han Y, Hu XJ, Zhou M, Lin SX. Structure analysis of a new psychrophilic marine protease. Plos One. 6: e26939. PMID 22132082 DOI: 10.1371/journal.pone.0026939 |
0.6 |
|
2011 |
Gilbert C, Azzi A, Goyette N, Lin SX, Boivin G. Recombinant phenotyping of cytomegalovirus UL54 mutations that emerged during cell passages in the presence of either ganciclovir or foscarnet. Antimicrobial Agents and Chemotherapy. 55: 4019-27. PMID 21709106 DOI: 10.1128/AAC.00334-11 |
0.48 |
|
2011 |
Zhang CY, Mazumdar M, Zhu DW, Yin DC, Lin SX. Analysis and statistics of crystallisation success increase by composition modification of protein and precipitant mixing ratio. Protein and Peptide Letters. 18: 991-6. PMID 21592082 |
0.48 |
|
2010 |
Lin SX, Chen J, Mazumdar M, Poirier D, Wang C, Azzi A, Zhou M. Molecular therapy of breast cancer: progress and future directions. Nature Reviews. Endocrinology. 6: 485-93. PMID 20644568 DOI: 10.1038/nrendo.2010.92 |
0.6 |
|
2010 |
Martin M, Azzi A, Lin SX, Boivin G. Opposite effect of two cytomegalovirus DNA polymerase mutations on replicative capacity and polymerase activity. Antiviral Therapy. 15: 579-86. PMID 20587851 DOI: 10.3851/IMP1565 |
0.48 |
|
2009 |
Mazumdar M, Fournier D, Zhu DW, Cadot C, Poirier D, Lin SX. Binary and ternary crystal structure analyses of a novel inhibitor with 17beta-HSD type 1: a lead compound for breast cancer therapy. The Biochemical Journal. 424: 357-66. PMID 19929851 DOI: 10.1042/BJ20091020 |
0.48 |
|
2009 |
Bao R, Zhou CZ, Jiang C, Lin SX, Chi CW, Chen Y. The ternary structure of the double-headed arrowhead protease inhibitor API-A complexed with two trypsins reveals a novel reactive site conformation. The Journal of Biological Chemistry. 284: 26676-84. PMID 19640842 DOI: 10.1074/jbc.M109.022095 |
0.44 |
|
2009 |
Azzi A, Wang T, Zhu DW, Zou YS, Liu WY, Lin SX. Crystal structure of native cinnamomin isoform III and its comparison with other ribosome inactivating proteins. Proteins. 74: 250-5. PMID 18837036 DOI: 10.1002/prot.22251 |
0.48 |
|
2007 |
Azzi A, Lin SX. Structure function analysis of west nile virus RNA dependent RNA polymerase: molecular model and implications for drug design. Medicinal Chemistry (ShāRiqah (United Arab Emirates)). 3: 455-9. PMID 17897070 |
0.48 |
|
2007 |
Qiu W, Zhou M, Mazumdar M, Azzi A, Ghanmi D, Luu-The V, Labrie F, Lin SX. Structure-based inhibitor design for an enzyme that binds different steroids: a potent inhibitor for human type 5 17beta-hydroxysteroid dehydrogenase. The Journal of Biological Chemistry. 282: 8368-79. PMID 17166832 DOI: 10.1074/jbc.M606784200 |
0.6 |
|
2006 |
Shi R, Azzi A, Gilbert C, Boivin G, Lin SX. Three-dimensional modeling of cytomegalovirus DNA polymerase and preliminary analysis of drug resistance. Proteins. 64: 301-7. PMID 16705640 DOI: 10.1002/prot.21005 |
0.52 |
|
2006 |
Poirier D, Chang HJ, Azzi A, Boivin RP, Lin SX. Estrone and estradiol C-16 derivatives as inhibitors of type 1 17beta-hydroxysteroid dehydrogenase. Molecular and Cellular Endocrinology. 248: 236-8. PMID 16337735 DOI: 10.1016/j.mce.2005.10.017 |
0.6 |
|
2005 |
Poirier D, Boivin RP, Tremblay MR, Bérubé M, Qiu W, Lin SX. Estradiol-adenosine hybrid compounds designed to inhibit type 1 17beta-hydroxysteroid dehydrogenase. Journal of Medicinal Chemistry. 48: 8134-47. PMID 16366595 DOI: 10.1021/jm058235e |
0.6 |
|
2004 |
Qiu W, Shi R, Lu ML, Zhou M, Roy PH, Lapointe J, Lin SX. Crystal structure of chloramphenicol acetyltransferase B2 encoded by the multiresistance transposon Tn2424. Proteins. 57: 858-61. PMID 15390264 DOI: 10.1002/prot.20250 |
0.6 |
|
2004 |
Azzi A, Lin SX. Human SARS-coronavirus RNA-dependent RNA polymerase: activity determinants and nucleoside analogue inhibitors. Proteins. 57: 12-4. PMID 15326590 DOI: 10.1002/prot.20194 |
0.48 |
|
2004 |
Qiu W, Zhou M, Labrie F, Lin SX. Crystal structures of the multispecific 17beta-hydroxysteroid dehydrogenase type 5: critical androgen regulation in human peripheral tissues. Molecular Endocrinology (Baltimore, Md.). 18: 1798-807. PMID 15087468 DOI: 10.1210/me.2004-0032 |
0.6 |
|
2004 |
Shi R, Lin SX. Cofactor hydrogen bonding onto the protein main chain is conserved in the short chain dehydrogenase/reductase family and contributes to nicotinamide orientation. The Journal of Biological Chemistry. 279: 16778-85. PMID 14966133 DOI: 10.1074/jbc.M313156200 |
0.52 |
|
2004 |
Chang HJ, Shi R, Rehse P, Lin SX. Identifying androsterone (ADT) as a cognate substrate for human dehydroepiandrosterone sulfotransferase (DHEA-ST) important for steroid homeostasis: structure of the enzyme-ADT complex. The Journal of Biological Chemistry. 279: 2689-96. PMID 14573603 DOI: 10.1074/jbc.M310446200 |
0.6 |
|
2003 |
Nahoum V, Gangloff A, Shi R, Lin SX. How estrogen-specific proteins discriminate estrogens from androgens: a common steroid binding site architecture. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1334-6. PMID 12759331 DOI: 10.1096/fj.02-0524fje |
0.72 |
|
2003 |
Labrie F, Luu-The V, Labrie C, Bélanger A, Simard J, Lin SX, Pelletier G. Endocrine and intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone. Endocrine Reviews. 24: 152-82. PMID 12700178 DOI: 10.1210/er.2001-0031 |
0.32 |
|
2003 |
Gangloff A, Shi R, Nahoum V, Lin SX. Pseudo-symmetry of C19 steroids, alternative binding orientations, and multispecificity in human estrogenic 17beta-hydroxysteroid dehydrogenase. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 274-6. PMID 12490543 DOI: 10.1096/fj.02-0397fje |
0.72 |
|
2002 |
Qiu W, Campbell RL, Gangloff A, Dupuis P, Boivin RP, Tremblay MR, Poirier D, Lin SX. A concerted, rational design of type 1 17beta-hydroxysteroid dehydrogenase inhibitors: estradiol-adenosine hybrids with high affinity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 1829-31. PMID 12223444 DOI: 10.1096/fj.02-0026fje |
0.72 |
|
2002 |
Zhou M, Qiu W, Chang HJ, Gangloff A, Lin SX. Purification, crystallization and preliminary X-ray diffraction results of human 17beta-hydroxysteroid dehydrogenase type 5. Acta Crystallographica. Section D, Biological Crystallography. 58: 1048-50. PMID 12037313 |
0.72 |
|
2002 |
Rehse PH, Zhou M, Lin SX. Crystal structure of human dehydroepiandrosterone sulphotransferase in complex with substrate. The Biochemical Journal. 364: 165-71. PMID 11988089 |
0.6 |
|
2002 |
Lu ML, Huang YW, Lin SX. Purification, reconstitution, and steady-state kinetics of the trans-membrane 17 beta-hydroxysteroid dehydrogenase 2. The Journal of Biological Chemistry. 277: 22123-30. PMID 11940569 DOI: 10.1074/jbc.M111726200 |
0.72 |
|
2001 |
Huang YW, Pineau I, Chang HJ, Azzi A, Bellemare V, Laberge S, Lin SX. Critical residues for the specificity of cofactors and substrates in human estrogenic 17beta-hydroxysteroid dehydrogenase 1: variants designed from the three-dimensional structure of the enzyme. Molecular Endocrinology (Baltimore, Md.). 15: 2010-20. PMID 11682630 DOI: 10.1210/mend.15.11.0730 |
0.72 |
|
2001 |
Zhou M, Rehse P, Chang HJ, Luu-The V, Lin SX. Crystallization and preliminary crystallographic results of apo and complex forms of human dehydroepiandrosterone sulfotransferase. Acta Crystallographica. Section D, Biological Crystallography. 57: 1630-3. PMID 11679728 |
0.6 |
|
2001 |
Nahoum V, Gangloff A, Legrand P, Zhu DW, Cantin L, Zhorov BS, Luu-The V, Labrie F, Breton R, Lin SX. Structure of the human 3alpha-hydroxysteroid dehydrogenase type 3 in complex with testosterone and NADP at 1.25-A resolution. The Journal of Biological Chemistry. 276: 42091-8. PMID 11514561 DOI: 10.1074/jbc.M105610200 |
0.72 |
|
2001 |
Chang HJ, Zhou M, Lin SX. Human dehydroepiandrosterone sulfotransferase: purification and characterization of a recombinant protein. The Journal of Steroid Biochemistry and Molecular Biology. 77: 159-65. PMID 11377982 |
0.6 |
|
2001 |
Gangloff A, Garneau A, Huang YW, Yang F, Lin SX. Human oestrogenic 17beta-hydroxysteroid dehydrogenase specificity: enzyme regulation through an NADPH-dependent substrate inhibition towards the highly specific oestrone reduction. The Biochemical Journal. 356: 269-76. PMID 11336660 |
0.72 |
|
2000 |
Lin SX, Han Q, Azzi A, Zhu D, Gangloff A, Campbell RL. 3D-structure of human estrogenic 17beta-HSD1: binding with various steroids. The Journal of Steroid Biochemistry and Molecular Biology. 73: 183. PMID 10925218 |
0.72 |
|
2000 |
Huang YW, Lu ML, Qi H, Lin SX. Membrane-bound human 3beta-hydroxysteroid dehydrogenase: overexpression with His-tag using a baculovirus system and single-step purification. Protein Expression and Purification. 18: 169-74. PMID 10686147 DOI: 10.1006/prep.1999.1180 |
0.72 |
|
2000 |
Han Q, Campbell RL, Gangloff A, Huang YW, Lin SX. Dehydroepiandrosterone and dihydrotestosterone recognition by human estrogenic 17beta-hydroxysteroid dehydrogenase. C-18/c-19 steroid discrimination and enzyme-induced strain. The Journal of Biological Chemistry. 275: 1105-11. PMID 10625652 |
0.72 |
|
1999 |
Lin SX, Han Q, Azzi A, Zhu DW, Gangloff A, Campbell RL, Gongloff A. 3D-structure of human estrogenic 17beta-HSD1: binding with various steroids. The Journal of Steroid Biochemistry and Molecular Biology. 69: 425-9. PMID 10419021 |
0.72 |
|
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