| Year |
Citation |
Score |
| 2022 |
Shearn CT, Anderson AL, Devereux MW, Orlicky DJ, Michel C, Petersen DR, Miller CG, Harpavat S, Schmidt EE, Sokol RJ. The autophagic protein p62 is a target of reactive aldehydes in human and murine cholestatic liver disease. Plos One. 17: e0276879. PMID 36378690 DOI: 10.1371/journal.pone.0276879 |
0.374 |
|
| 2019 |
Shearn CT, Fennimore B, Orlicky DJ, Gao YR, Saba LM, Battista KD, Aivazidis S, Assiri M, Harris PS, Michel C, Merrill GF, Schmidt EE, Colgan SP, Petersen DR. Cholestatic liver disease results increased production of reactive aldehydes and an atypical periportal hepatic antioxidant response. Free Radical Biology & Medicine. PMID 31377417 DOI: 10.1016/J.Freeradbiomed.2019.07.036 |
0.51 |
|
| 2018 |
Petersen DR, Orlicky DJ, Roede JR, Shearn CT. Aberrant expression of redox regulatory proteins in patients with concomitant primary Sclerosing cholangitis/inflammatory bowel disease. Experimental and Molecular Pathology. 105: 32-36. PMID 29852184 DOI: 10.1016/J.Yexmp.2018.05.012 |
0.672 |
|
| 2018 |
Petersen DR, Saba LM, Sayin VI, Papagiannakopoulos T, Schmidt EE, Merrill GF, Orlicky DJ, Shearn CT. Elevated Nrf-2 responses are insufficient to mitigate protein carbonylation in hepatospecific PTEN deletion mice. Plos One. 13: e0198139. PMID 29799837 DOI: 10.1371/Journal.Pone.0198139 |
0.46 |
|
| 2018 |
Shearn CT, Pulliam CF, Pedersen K, Meredith K, Mercer KE, Saba LM, Orlicky DJ, Ronis MJ, Petersen DR. Knock-out of the Gsta4 gene in male mice leads to an altered pattern of hepatic protein carbonylation and enhanced inflammation following chronic consumption of an ethanol diet. Alcoholism, Clinical and Experimental Research. PMID 29708596 DOI: 10.1111/Acer.13766 |
0.424 |
|
| 2017 |
Shearn CT, Orlicky DJ, Petersen DR. Dysregulation of antioxidant responses in patients diagnosed with concomitant Primary Sclerosing Cholangitis/Inflammatory Bowel Disease. Experimental and Molecular Pathology. 104: 1-8. PMID 29180269 DOI: 10.1016/J.Yexmp.2017.11.012 |
0.362 |
|
| 2017 |
Maclean KN, Jiang H, Aivazidis S, Kim E, Shearn CT, Harris PS, Petersen DR, Allen RH, Stabler SP, Roede JR. Taurine treatment prevents derangement of the hepatic γ-glutamyl cycle and methylglyoxal metabolism in a mouse model of classical homocystinuria: regulatory crosstalk between thiol and sulfinic acid metabolism. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 29101223 DOI: 10.1096/Fj.201700586R |
0.688 |
|
| 2017 |
Shearn CT, Saba LM, Roede JR, Orlicky DJ, Shearn AH, Petersen DR. Differential carbonylation of proteins in end-stage human fatty and nonfatty NASH. Free Radical Biology & Medicine. PMID 28988798 DOI: 10.1016/J.Freeradbiomed.2017.10.004 |
0.694 |
|
| 2016 |
Ronis M, Mercer K, Engi B, Pulliam C, Zimniak P, Hennings L, Shearn C, Badger T, Petersen D. Global Deletion of Glutathione S-Transferase A4 Exacerbates Developmental Nonalcoholic Steatohepatitis. The American Journal of Pathology. PMID 27998724 DOI: 10.1016/J.Ajpath.2016.10.022 |
0.402 |
|
| 2016 |
Osna NA, Carter WG, Ganesan M, Kirpich IA, McClain CJ, Petersen DR, Shearn CT, Tomasi ML, Kharbanda KK. Aberrant post-translational protein modifications in the pathogenesis of alcohol-induced liver injury. World Journal of Gastroenterology. 22: 6192-6200. PMID 27468209 DOI: 10.3748/Wjg.V22.I27.6192 |
0.441 |
|
| 2016 |
Shearn CT, Orlicky DJ, McCullough RL, Jiang H, Maclean KN, Mercer KE, Stiles BL, Saba LM, Ronis MJ, Petersen DR. Liver-Specific Deletion of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Significantly Ameliorates Chronic EtOH-Induced Increases in Hepatocellular Damage. Plos One. 11: e0154152. PMID 27124661 DOI: 10.1371/Journal.Pone.0154152 |
0.456 |
|
| 2015 |
Shearn CT, Fritz KS, Shearn AH, Saba LM, Mercer KE, Engi B, Galligan JJ, Zimniak P, Orlicky DJ, Ronis MJ, Petersen DR. Deletion of GSTA4-4 results in increased mitochondrial post-translational modification of proteins by reactive aldehydes following chronic ethanol consumption in mice. Redox Biology. 7: 68-77. PMID 26654979 DOI: 10.1016/J.Redox.2015.11.013 |
0.653 |
|
| 2015 |
Shearn CT, Orlicky DJ, Saba LM, Shearn AH, Petersen DR. Increased hepatocellular protein carbonylation in human end-stage alcoholic cirrhosis. Free Radical Biology & Medicine. PMID 26518673 DOI: 10.1016/J.Freeradbiomed.2015.10.420 |
0.454 |
|
| 2015 |
Ronis MJ, Mercer KE, Gannon B, Engi B, Zimniak P, Shearn CT, Orlicky DJ, Albano E, Badger TM, Petersen DR. Increased 4-hydroxynonenal protein adducts in male GSTA4-4/PPAR-α double knockout mice enhance injury during early stages of alcoholic liver disease. American Journal of Physiology. Gastrointestinal and Liver Physiology. 308: G403-15. PMID 25501545 DOI: 10.1152/Ajpgi.00154.2014 |
0.34 |
|
| 2015 |
Shearn CT, Petersen DR. Understanding the tumor suppressor PTEN in chronic alcoholism and hepatocellular carcinoma. Advances in Experimental Medicine and Biology. 815: 173-84. PMID 25427907 DOI: 10.1007/978-3-319-09614-8_10 |
0.346 |
|
| 2014 |
Caro AA, Bell M, Ejiofor S, Zurcher G, Petersen DR, Ronis MJ. N-acetylcysteine inhibits the up-regulation of mitochondrial biogenesis genes in livers from rats fed ethanol chronically. Alcoholism, Clinical and Experimental Research. 38: 2896-906. PMID 25581647 DOI: 10.1111/Acer.12576 |
0.37 |
|
| 2014 |
Galligan JJ, Fritz KS, Backos DS, Shearn CT, Smathers RL, Jiang H, MacLean KN, Reigan PR, Petersen DR. Oxidative stress-mediated aldehyde adduction of GRP78 in a mouse model of alcoholic liver disease: functional independence of ATPase activity and chaperone function. Free Radical Biology & Medicine. 73: 411-20. PMID 24924946 DOI: 10.1016/J.Freeradbiomed.2014.06.002 |
0.611 |
|
| 2014 |
Shearn CT, Mercer KE, Orlicky DJ, Hennings L, Smathers-McCullough RL, Stiles BL, Ronis MJ, Petersen DR. Short term feeding of a high fat diet exerts an additive effect on hepatocellular damage and steatosis in liver-specific PTEN knockout mice. Plos One. 9: e96553. PMID 24818992 DOI: 10.1371/Journal.Pone.0096553 |
0.327 |
|
| 2014 |
Shearn CT, Backos DS, Orlicky DJ, Smathers-McCullough RL, Petersen DR. Identification of 5' AMP-activated kinase as a target of reactive aldehydes during chronic ingestion of high concentrations of ethanol. The Journal of Biological Chemistry. 289: 15449-62. PMID 24722988 DOI: 10.1074/Jbc.M113.543942 |
0.491 |
|
| 2013 |
Fritz KS, Green MF, Petersen DR, Hirschey MD. Ethanol metabolism modifies hepatic protein acylation in mice. Plos One. 8: e75868. PMID 24073283 DOI: 10.1371/Journal.Pone.0075868 |
0.429 |
|
| 2013 |
Shearn CT, Smathers RL, Backos DS, Reigan P, Orlicky DJ, Petersen DR. Increased carbonylation of the lipid phosphatase PTEN contributes to Akt2 activation in a murine model of early alcohol-induced steatosis. Free Radical Biology & Medicine. 65: 680-92. PMID 23872024 DOI: 10.1016/J.Freeradbiomed.2013.07.011 |
0.478 |
|
| 2013 |
Backos DS, Fritz KS, McArthur DG, Kepa JK, Donson AM, Petersen DR, Foreman NK, Franklin CC, Reigan P. Glycation of glutamate cysteine ligase by 2-deoxy-d-ribose and its potential impact on chemoresistance in glioblastoma. Neurochemical Research. 38: 1838-49. PMID 23743623 DOI: 10.1007/S11064-013-1090-4 |
0.367 |
|
| 2013 |
Shearn CT, Smathers RL, Jiang H, Orlicky DJ, Maclean KN, Petersen DR. Increased dietary fat contributes to dysregulation of the LKB1/AMPK pathway and increased damage in a mouse model of early-stage ethanol-mediated steatosis. The Journal of Nutritional Biochemistry. 24: 1436-45. PMID 23465594 DOI: 10.1016/J.Jnutbio.2012.12.002 |
0.381 |
|
| 2013 |
Smathers RL, Galligan JJ, Shearn CT, Fritz KS, Mercer K, Ronis M, Orlicky DJ, Davidson NO, Petersen DR. Susceptibility of L-FABP-/- mice to oxidative stress in early-stage alcoholic liver. Journal of Lipid Research. 54: 1335-45. PMID 23359610 DOI: 10.1194/Jlr.M034892 |
0.635 |
|
| 2013 |
Fritz KS, Petersen DR. An overview of the chemistry and biology of reactive aldehydes. Free Radical Biology & Medicine. 59: 85-91. PMID 22750507 DOI: 10.1016/J.Freeradbiomed.2012.06.025 |
0.41 |
|
| 2012 |
Galligan JJ, Petersen DR. The human protein disulfide isomerase gene family. Human Genomics. 6: 6. PMID 23245351 DOI: 10.1186/1479-7364-6-6 |
0.576 |
|
| 2012 |
Galligan JJ, Smathers RL, Shearn CT, Fritz KS, Backos DS, Jiang H, Franklin CC, Orlicky DJ, Maclean KN, Petersen DR. Oxidative Stress and the ER Stress Response in a Murine Model for Early-Stage Alcoholic Liver Disease. Journal of Toxicology. 2012: 207594. PMID 22829816 DOI: 10.1155/2012/207594 |
0.623 |
|
| 2012 |
Smathers RL, Fritz KS, Galligan JJ, Shearn CT, Reigan P, Marks MJ, Petersen DR. Characterization of 4-HNE modified L-FABP reveals alterations in structural and functional dynamics. Plos One. 7: e38459. PMID 22701647 DOI: 10.1371/Journal.Pone.0038459 |
0.573 |
|
| 2012 |
Shearn CT, Reigan P, Petersen DR. Inhibition of hydrogen peroxide signaling by 4-hydroxynonenal due to differential regulation of Akt1 and Akt2 contributes to decreases in cell survival and proliferation in hepatocellular carcinoma cells. Free Radical Biology & Medicine. 53: 1-11. PMID 22580126 DOI: 10.1016/J.Freeradbiomed.2012.04.021 |
0.387 |
|
| 2012 |
Koppaka V, Thompson DC, Chen Y, Ellermann M, Nicolaou KC, Juvonen RO, Petersen D, Deitrich RA, Hurley TD, Vasiliou V. Aldehyde dehydrogenase inhibitors: a comprehensive review of the pharmacology, mechanism of action, substrate specificity, and clinical application. Pharmacological Reviews. 64: 520-39. PMID 22544865 DOI: 10.1124/Pr.111.005538 |
0.368 |
|
| 2012 |
Galligan JJ, Smathers RL, Fritz KS, Epperson LE, Hunter LE, Petersen DR. Protein carbonylation in a murine model for early alcoholic liver disease. Chemical Research in Toxicology. 25: 1012-21. PMID 22502949 DOI: 10.1021/Tx300002Q |
0.669 |
|
| 2012 |
Fritz KS, Kellersberger KA, Gomez JD, Petersen DR. 4-HNE adduct stability characterized by collision-induced dissociation and electron transfer dissociation mass spectrometry. Chemical Research in Toxicology. 25: 965-70. PMID 22404378 DOI: 10.1021/Tx300100W |
0.307 |
|
| 2012 |
Fritz KS, Galligan JJ, Hirschey MD, Verdin E, Petersen DR. Mitochondrial acetylome analysis in a mouse model of alcohol-induced liver injury utilizing SIRT3 knockout mice. Journal of Proteome Research. 11: 1633-43. PMID 22309199 DOI: 10.1016/J.Freeradbiomed.2011.10.044 |
0.627 |
|
| 2012 |
Petersen⁎ D, Galligan J. Protein Adduct Formation by Endogenous Lipid Electrophiles: What we are learning through studies of mechanistic Links with alcohol-Induced Liver Injury Free Radical Biology and Medicine. 53: S238-S239. DOI: 10.1016/j.freeradbiomed.2012.08.019 |
0.555 |
|
| 2011 |
Gentile CL, Nivala AM, Gonzales JC, Pfaffenbach KT, Wang D, Wei Y, Jiang H, Orlicky DJ, Petersen DR, Pagliassotti MJ, Maclean KN. Experimental evidence for therapeutic potential of taurine in the treatment of nonalcoholic fatty liver disease. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 301: R1710-22. PMID 21957160 DOI: 10.1152/Ajpregu.00677.2010 |
0.46 |
|
| 2011 |
Fritz KS, Petersen DR. Exploring the biology of lipid peroxidation-derived protein carbonylation. Chemical Research in Toxicology. 24: 1411-9. PMID 21812433 DOI: 10.1021/Tx200169N |
0.435 |
|
| 2011 |
Vassilopoulos A, Fritz KS, Petersen DR, Gius D. The human sirtuin family: evolutionary divergences and functions. Human Genomics. 5: 485-96. PMID 21807603 DOI: 10.1186/1479-7364-5-5-485 |
0.315 |
|
| 2011 |
Setshedi M, Longato L, Petersen DR, Ronis M, Chen WC, Wands JR, de la Monte SM. Limited therapeutic effect of N-acetylcysteine on hepatic insulin resistance in an experimental model of alcohol-induced steatohepatitis. Alcoholism, Clinical and Experimental Research. 35: 2139-51. PMID 21790669 DOI: 10.1111/J.1530-0277.2011.01569.X |
0.409 |
|
| 2011 |
Orlicky DJ, Roede JR, Bales E, Greenwood C, Greenberg A, Petersen D, McManaman JL. Chronic ethanol consumption in mice alters hepatocyte lipid droplet properties. Alcoholism, Clinical and Experimental Research. 35: 1020-33. PMID 21535024 DOI: 10.1111/J.1530-0277.2011.01434.X |
0.723 |
|
| 2011 |
Smathers RL, Petersen DR. The human fatty acid-binding protein family: evolutionary divergences and functions. Human Genomics. 5: 170-91. PMID 21504868 DOI: 10.1186/1479-7364-5-3-170 |
0.331 |
|
| 2011 |
Fritz KS, Galligan JJ, Smathers RL, Roede JR, Shearn CT, Reigan P, Petersen DR. 4-Hydroxynonenal inhibits SIRT3 via thiol-specific modification. Chemical Research in Toxicology. 24: 651-62. PMID 21449565 DOI: 10.1021/Tx100355A |
0.777 |
|
| 2011 |
Shearn CT, Fritz KS, Reigan P, Petersen DR. Modification of Akt2 by 4-hydroxynonenal inhibits insulin-dependent Akt signaling in HepG2 cells. Biochemistry. 50: 3984-96. PMID 21438592 DOI: 10.1021/Bi200029W |
0.394 |
|
| 2011 |
Shearn CT, Smathers RL, Stewart BJ, Fritz KS, Galligan JJ, Hail N, Petersen DR. Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibition by 4-hydroxynonenal leads to increased Akt activation in hepatocytes. Molecular Pharmacology. 79: 941-52. PMID 21415306 DOI: 10.1124/Mol.110.069534 |
0.625 |
|
| 2011 |
Smathers RL, Galligan JJ, Stewart BJ, Petersen DR. Overview of lipid peroxidation products and hepatic protein modification in alcoholic liver disease. Chemico-Biological Interactions. 192: 107-12. PMID 21354120 DOI: 10.1016/J.Cbi.2011.02.021 |
0.655 |
|
| 2011 |
Galligan JJ, Fritz KS, Tipney H, Smathers RL, Roede JR, Shearn CT, Hunter LE, Petersen DR. Profiling impaired hepatic endoplasmic reticulum glycosylation as a consequence of ethanol ingestion. Journal of Proteome Research. 10: 1837-47. PMID 21319786 DOI: 10.1021/Pr101101S |
0.777 |
|
| 2011 |
Ronis MJ, Hennings L, Stewart B, Basnakian AG, Apostolov EO, Albano E, Badger TM, Petersen DR. Effects of long-term ethanol administration in a rat total enteral nutrition model of alcoholic liver disease. American Journal of Physiology. Gastrointestinal and Liver Physiology. 300: G109-19. PMID 21051528 DOI: 10.1152/Ajpgi.00145.2010 |
0.357 |
|
| 2011 |
Backos DS, Fritz KS, Roede JR, Petersen DR, Franklin CC. Posttranslational modification and regulation of glutamate-cysteine ligase by the α,β-unsaturated aldehyde 4-hydroxy-2-nonenal. Free Radical Biology & Medicine. 50: 14-26. PMID 20970495 DOI: 10.1016/J.Freeradbiomed.2010.10.694 |
0.706 |
|
| 2011 |
Smathers RL, Reigan P, Fritz KS, Galligan JJ, Shearn CT, Petersen DR. 4-HNE Significantly Alters L-FABP Structural and Functional Dynamics Free Radical Biology and Medicine. 51: S140. DOI: 10.1016/J.Freeradbiomed.2011.10.298 |
0.468 |
|
| 2011 |
Galligan JJ, Fritz KS, Smathers RL, Petersen DR. Profiling Protein Carbonylation in a Murine Model of Alcoholic Liver Disease Free Radical Biology and Medicine. 51: S20. DOI: 10.1016/J.Freeradbiomed.2011.10.046 |
0.597 |
|
| 2010 |
Smathers RL, Fritz KS, Galligan JJ, Shearn CT, Petersen DR. Identification and Characterization of 4-HNE-Modified Liver Fatty Acid Binding Protein in a Rodent Model of Alcoholic Liver Disease Free Radical Biology and Medicine. 49: S103. DOI: 10.1016/J.Freeradbiomed.2010.10.271 |
0.606 |
|
| 2010 |
Galligan J, Fritz K, Smathers R, Shearn C, Petersen D. Oxidative Stress and the Unfolded Protein Response: A Disconnect in Alcoholic Liver Disease Free Radical Biology and Medicine. 49: S94-S95. DOI: 10.1016/J.Freeradbiomed.2010.10.243 |
0.618 |
|
| 2010 |
Fritz KS, Galligan JJ, Smathers RL, Roede JR, Shearn CT, Reigan P, Petersen DR. Reactive Aldehyde 4-Hydroxynonenal Inhibits Mitochondrial Sirt3 Deacetylase Activity Free Radical Biology and Medicine. 49: S87. DOI: 10.1016/J.Freeradbiomed.2010.10.221 |
0.699 |
|
| 2009 |
Stewart BJ, Roede JR, Doorn JA, Petersen DR. Lipid aldehyde-mediated cross-linking of apolipoprotein B-100 inhibits secretion from HepG2 cells. Biochimica Et Biophysica Acta. 1791: 772-80. PMID 19393338 DOI: 10.1016/J.Bbalip.2009.04.004 |
0.728 |
|
| 2009 |
Roede JR, Orlicky DJ, Fisher AB, Petersen DR. Overexpression of peroxiredoxin 6 does not prevent ethanol-mediated oxidative stress and may play a role in hepatic lipid accumulation. The Journal of Pharmacology and Experimental Therapeutics. 330: 79-88. PMID 19386791 DOI: 10.1124/Jpet.109.152983 |
0.706 |
|
| 2008 |
Roede JR, Carbone DL, Doorn JA, Kirichenko OV, Reigan P, Petersen DR. In vitro and in silico characterization of peroxiredoxin 6 modified by 4-hydroxynonenal and 4-oxononenal. Chemical Research in Toxicology. 21: 2289-99. PMID 19548352 DOI: 10.1021/Tx800244U |
0.789 |
|
| 2008 |
Roede JR, Stewart BJ, Petersen DR. Decreased expression of peroxiredoxin 6 in a mouse model of ethanol consumption. Free Radical Biology & Medicine. 45: 1551-8. PMID 18852041 DOI: 10.1016/J.Freeradbiomed.2008.08.032 |
0.731 |
|
| 2008 |
Cheng L, Stewart BJ, You Q, Petersen DR, Ware JA, Piccotti JR, Kawabata TT, Ju C. Covalent binding of the nitroso metabolite of sulfamethoxazole is important in induction of drug-specific T-cell responses in vivo. Molecular Pharmacology. 73: 1769-75. PMID 18334600 DOI: 10.1124/Mol.107.043273 |
0.339 |
|
| 2007 |
Stewart BJ, Doorn JA, Petersen DR. Residue-specific adduction of tubulin by 4-hydroxynonenal and 4-oxononenal causes cross-linking and inhibits polymerization. Chemical Research in Toxicology. 20: 1111-9. PMID 17630713 DOI: 10.1021/Tx700106V |
0.398 |
|
| 2007 |
Sampey BP, Carbone DL, Doorn JA, Drechsel DA, Petersen DR. 4-Hydroxy-2-nonenal adduction of extracellular signal-regulated kinase (Erk) and the inhibition of hepatocyte Erk-Est-like protein-1-activating protein-1 signal transduction. Molecular Pharmacology. 71: 871-83. PMID 17164404 DOI: 10.1124/Mol.106.029686 |
0.787 |
|
| 2007 |
Sampey BP, Stewart BJ, Petersen DR. Ethanol-induced modulation of hepatocellular extracellular signal-regulated kinase-1/2 activity via 4-hydroxynonenal. The Journal of Biological Chemistry. 282: 1925-37. PMID 17107949 DOI: 10.1074/jbc.M610602200 |
0.769 |
|
| 2006 |
Reichard JF, Petersen DR. Involvement of phosphatidylinositol 3-kinase and extracellular-regulated kinase in hepatic stellate cell antioxidant response and myofibroblastic transdifferentiation. Archives of Biochemistry and Biophysics. 446: 111-8. PMID 16455043 DOI: 10.1016/J.Abb.2005.12.011 |
0.743 |
|
| 2006 |
Doorn JA, Hurley TD, Petersen DR. Inhibition of human mitochondrial aldehyde dehydrogenase by 4-hydroxynon-2-enal and 4-oxonon-2-enal. Chemical Research in Toxicology. 19: 102-10. PMID 16411662 DOI: 10.1021/Tx0501839 |
0.373 |
|
| 2006 |
Vasiliou V, Ziegler TL, Bludeau P, Petersen DR, Gonzalez FJ, Deitrich RA. CYP2E1 and catalase influence ethanol sensitivity in the central nervous system. Pharmacogenetics and Genomics. 16: 51-8. PMID 16344722 DOI: 10.1097/01.Fpc.0000182777.95555.56 |
0.353 |
|
| 2005 |
Carbone DL, Doorn JA, Kiebler Z, Petersen DR. Cysteine modification by lipid peroxidation products inhibits protein disulfide isomerase. Chemical Research in Toxicology. 18: 1324-31. PMID 16097806 DOI: 10.1021/Tx050078Z |
0.767 |
|
| 2005 |
Ronis MJ, Butura A, Sampey BP, Shankar K, Prior RL, Korourian S, Albano E, Ingelman-Sundberg M, Petersen DR, Badger TM. Effects of N-acetylcysteine on ethanol-induced hepatotoxicity in rats fed via total enteral nutrition. Free Radical Biology & Medicine. 39: 619-30. PMID 16085180 DOI: 10.1016/J.Freeradbiomed.2005.04.011 |
0.777 |
|
| 2005 |
Petersen DR. Alcohol, iron-associated oxidative stress, and cancer. Alcohol (Fayetteville, N.Y.). 35: 243-9. PMID 16054986 DOI: 10.1016/J.Alcohol.2005.03.013 |
0.41 |
|
| 2005 |
Carbone DL, Doorn JA, Kiebler Z, Ickes BR, Petersen DR. Modification of heat shock protein 90 by 4-hydroxynonenal in a rat model of chronic alcoholic liver disease. The Journal of Pharmacology and Experimental Therapeutics. 315: 8-15. PMID 15951401 DOI: 10.1124/Jpet.105.088088 |
0.762 |
|
| 2004 |
Carbone DL, Doorn JA, Kiebler Z, Sampey BP, Petersen DR. Inhibition of Hsp72-mediated protein refolding by 4-hydroxy-2-nonenal. Chemical Research in Toxicology. 17: 1459-67. PMID 15540944 DOI: 10.1021/Tx049838G |
0.793 |
|
| 2004 |
Doorn JA, Maser E, Blum A, Claffey DJ, Petersen DR. Human carbonyl reductase catalyzes reduction of 4-oxonon-2-enal. Biochemistry. 43: 13106-14. PMID 15476404 DOI: 10.1021/Bi049136Q |
0.341 |
|
| 2004 |
Carbone DL, Doorn JA, Petersen DR. 4-Hydroxynonenal regulates 26S proteasomal degradation of alcohol dehydrogenase. Free Radical Biology & Medicine. 37: 1430-9. PMID 15454282 DOI: 10.1016/J.Freeradbiomed.2004.07.016 |
0.737 |
|
| 2004 |
Reichard JF, Petersen DR. Hepatic stellate cells lack AP-1 responsiveness to electrophiles and phorbol 12-myristate-13-acetate. Biochemical and Biophysical Research Communications. 322: 842-53. PMID 15336540 DOI: 10.1016/J.Bbrc.2004.07.180 |
0.748 |
|
| 2004 |
Petersen DR, Doorn JA. Reactions of 4-hydroxynonenal with proteins and cellular targets. Free Radical Biology & Medicine. 37: 937-45. PMID 15336309 DOI: 10.1016/J.Freeradbiomed.2004.06.012 |
0.481 |
|
| 2004 |
Burcham PC, Fontaine FR, Kaminskas LM, Petersen DR, Pyke SM. Protein adduct-trapping by hydrazinophthalazine drugs: mechanisms of cytoprotection against acrolein-mediated toxicity. Molecular Pharmacology. 65: 655-64. PMID 14978244 DOI: 10.1124/Mol.65.3.655 |
0.368 |
|
| 2003 |
Doorn JA, Srivastava SK, Petersen DR. Aldose reductase catalyzes reduction of the lipid peroxidation product 4-oxonon-2-enal. Chemical Research in Toxicology. 16: 1418-23. PMID 14615967 DOI: 10.1021/Tx0300378 |
0.363 |
|
| 2003 |
Burcham PC, Fontaine FR, Petersen DR, Pyke SM. Reactivity with Tris(hydroxymethyl)aminomethane confounds immunodetection of acrolein-adducted proteins. Chemical Research in Toxicology. 16: 1196-201. PMID 14565760 DOI: 10.1021/Tx0341106 |
0.37 |
|
| 2003 |
Manzer R, Qamar L, Estey T, Pappa A, Petersen DR, Vasiliou V. Molecular cloning and baculovirus expression of the rabbit corneal aldehyde dehydrogenase (ALDH1A1) cDNA. Dna and Cell Biology. 22: 329-38. PMID 12941160 DOI: 10.1089/104454903322216671 |
0.417 |
|
| 2003 |
Sampey BP, Korourian S, Ronis MJ, Badger TM, Petersen DR. Immunohistochemical characterization of hepatic malondialdehyde and 4-hydroxynonenal modified proteins during early stages of ethanol-induced liver injury. Alcoholism, Clinical and Experimental Research. 27: 1015-22. PMID 12824824 DOI: 10.1097/01.Alc.0000071928.16732.26 |
0.773 |
|
| 2003 |
Vasiliou V, Qamar L, Pappa A, Sophos NA, Petersen DR. Involvement of the electrophile responsive element and p53 in the activation of hepatic stellate cells as a response to electrophile menadione. Archives of Biochemistry and Biophysics. 413: 164-71. PMID 12729613 DOI: 10.1016/S0003-9861(03)00095-X |
0.441 |
|
| 2003 |
Reichard JF, Doorn JA, Simon F, Taylor MS, Petersen DR. Characterization of multidrug resistance-associated protein 2 in the hepatocellular disposition of 4-hydroxynonenal. Archives of Biochemistry and Biophysics. 411: 243-50. PMID 12623073 DOI: 10.1016/S0003-9861(03)00002-X |
0.752 |
|
| 2003 |
Doorn JA, Petersen DR. Covalent adduction of nucleophilic amino acids by 4-hydroxynonenal and 4-oxononenal. Chemico-Biological Interactions. 143: 93-100. PMID 12604193 DOI: 10.1016/S0009-2797(02)00178-3 |
0.31 |
|
| 2002 |
Doorn JA, Petersen DR. Covalent modification of amino acid nucleophiles by the lipid peroxidation products 4-hydroxy-2-nonenal and 4-oxo-2-nonenal. Chemical Research in Toxicology. 15: 1445-50. PMID 12437335 DOI: 10.1021/Tx025590O |
0.317 |
|
| 2002 |
Fontaine FR, Dunlop RA, Petersen DR, Burcham PC. Oxidative bioactivation of crotyl alcohol to the toxic endogenous aldehyde crotonaldehyde: association of protein carbonylation with toxicity in mouse hepatocytes. Chemical Research in Toxicology. 15: 1051-8. PMID 12184789 DOI: 10.1021/Tx0255119 |
0.388 |
|
| 2002 |
Luckey SW, Taylor M, Sampey BP, Scheinman RI, Petersen DR. 4-hydroxynonenal decreases interleukin-6 expression and protein production in primary rat Kupffer cells by inhibiting nuclear factor-kappaB activation. The Journal of Pharmacology and Experimental Therapeutics. 302: 296-303. PMID 12065730 DOI: 10.1124/Jpet.102.033522 |
0.777 |
|
| 2001 |
Luckey SW, Petersen DR. Activation of Kupffer cells during the course of carbon tetrachloride-induced liver injury and fibrosis in rats. Experimental and Molecular Pathology. 71: 226-40. PMID 11733948 DOI: 10.1006/Exmp.2001.2399 |
0.785 |
|
| 2001 |
Luckey SW, Petersen DR. Metabolism of 4-hydroxynonenal by rat Kupffer cells. Archives of Biochemistry and Biophysics. 389: 77-83. PMID 11370675 DOI: 10.1006/Abbi.2001.2307 |
0.797 |
|
| 2000 |
Vasiliou V, Pappa A, Petersen DR. Role of aldehyde dehydrogenases in endogenous and xenobiotic metabolism Chemico-Biological Interactions. 129: 1-19. PMID 11154732 DOI: 10.1016/S0009-2797(00)00211-8 |
0.356 |
|
| 2000 |
Reichard JF, Vasiliou V, Petersen DR. Characterization of 4-hydroxy-2-nonenal metabolism in stellate cell lines derived from normal and cirrhotic rat liver. Biochimica Et Biophysica Acta. 1487: 222-32. PMID 11018474 DOI: 10.1016/S1388-1981(00)00095-0 |
0.737 |
|
| 2000 |
Vasiliou V, Lee J, Pappa A, Petersen DR. Involvement of p65 in the regulation of NF-κB in rat hepatic stellate cells during cirrhosis Biochemical and Biophysical Research Communications. 273: 546-550. PMID 10873642 DOI: 10.1006/Bbrc.2000.2993 |
0.329 |
|
| 2000 |
Valerio LG, Petersen DR. Characterization of hepatic iron overload following dietary administration of dicyclopentadienyl iron (Ferrocene) to mice: cellular, biochemical, and molecular aspects. Experimental and Molecular Pathology. 68: 1-12. PMID 10640449 DOI: 10.1006/Exmp.1999.2278 |
0.364 |
|
| 2000 |
Chen J, Petersen DR, Schenker S, Henderson GI. Formation of Malondialdehyde Adducts in Livers of Rats Exposed to Ethanol: Role in Ethanol-Mediated Inhibition of Cytochrome c Oxidase Alcoholism: Clinical and Experimental Research. 24: 544-552. DOI: 10.1111/J.1530-0277.2000.Tb02023.X |
0.444 |
|
| 1999 |
Hartley DP, Kolaja KL, Reichard J, Petersen DR. 4-Hydroxynonenal and malondialdehyde hepatic protein adducts in rats treated with carbon tetrachloride: immunochemical detection and lobular localization. Toxicology and Applied Pharmacology. 161: 23-33. PMID 10558920 DOI: 10.1006/Taap.1999.8788 |
0.76 |
|
| 1999 |
Tjalkens RB, Luckey SW, Kroll DJ, Petersen DR. Alpha, beta-unsaturated aldehydes mediate inducible expression of glutathione S-transferase in hepatoma cells through activation of the antioxidant response element (ARE). Advances in Experimental Medicine and Biology. 463: 123-31. PMID 10352677 |
0.74 |
|
| 1999 |
Luckey SW, Tjalkens RB, Petersen DR. Mechanism of inhibition of rat liver class 2 ALDH by 4-hydroxynonenal. Advances in Experimental Medicine and Biology. 463: 71-7. PMID 10352671 DOI: 10.1007/978-1-4615-4735-8_9 |
0.757 |
|
| 1999 |
Tjalkens RB, Cook LW, Petersen DR. Formation and export of the glutathione conjugate of 4-hydroxy-2, 3-E-nonenal (4-HNE) in hepatoma cells. Archives of Biochemistry and Biophysics. 361: 113-9. PMID 9882435 DOI: 10.1006/Abbi.1998.0946 |
0.413 |
|
| 1998 |
Tjalkens RB, Luckey SW, Kroll DJ, Petersen DR. Alpha,beta-unsaturated aldehydes increase glutathione S-transferase mRNA and protein: correlation with activation of the antioxidant response element. Archives of Biochemistry and Biophysics. 359: 42-50. PMID 9799558 DOI: 10.1006/Abbi.1998.0895 |
0.759 |
|
| 1998 |
Valerio LG, Petersen DR. Formation of liver microsomal MDA-protein adducts in mice with chronic dietary iron overload. Toxicology Letters. 98: 31-9. PMID 9776559 DOI: 10.1016/S0378-4274(98)00100-3 |
0.406 |
|
| 1998 |
Tjalkens RB, Valerio LG, Awasthi YC, Petersen DR. Association of glutathione S-transferase isozyme-specific induction and lipid peroxidation in two inbred strains of mice subjected to chronic dietary iron overload Toxicology and Applied Pharmacology. 151: 174-181. PMID 9705901 DOI: 10.1006/Taap.1998.8430 |
0.379 |
|
| 1997 |
Hartley DP, Kroll DJ, Petersen DR. Prooxidant-initiated lipid peroxidation in isolated rat hepatocytes: detection of 4-hydroxynonenal- and malondialdehyde-protein adducts. Chemical Research in Toxicology. 10: 895-905. PMID 9282839 DOI: 10.1021/Tx960181B |
0.456 |
|
| 1997 |
Hartley DP, Petersen DR. Profiles of hepatic cellular protein adduction by malondialdehyde and 4-hydroxynonenal. Studies with isolated hepatocytes. Advances in Experimental Medicine and Biology. 414: 123-31. PMID 9059614 DOI: 10.1007/978-1-4615-5871-2_15 |
0.393 |
|
| 1997 |
Valerio LG, Parks T, Petersen DR. Alcohol mediates increases in hepatic and serum nonheme iron stores in a rat model for alcohol-induced liver injury. Alcoholism, Clinical and Experimental Research. 20: 1352-61. PMID 8947310 DOI: 10.1111/J.1530-0277.1996.Tb01134.X |
0.336 |
|
| 1997 |
Hartley DP, Petersen DR. Co-Metabolism of Ethanol, Ethanol-Derived Acetaldehyde, and 4-Hydroxynonenal in Isolated Rat Hepatocytes Alcoholism: Clinical and Experimental Research. 21: 298-304. DOI: 10.1111/J.1530-0277.1997.Tb03764.X |
0.391 |
|
| 1995 |
Hartley DP, Lindahl R, Petersen DR. Covalent modification of class 2 and class 3 aldehyde dehydrogenase by 4-hydroxynonenal. Advances in Experimental Medicine and Biology. 372: 93-101. PMID 7484416 DOI: 10.1007/978-1-4615-1965-2_13 |
0.397 |
|
| 1994 |
Singhal SS, Zimniak P, Awasthi S, Piper JT, He NG, Teng JI, Petersen DR, Awasthi YC. Several closely related glutathione S-transferase isozymes catalyzing conjugation of 4-hydroxynonenal are differentially expressed in human tissues. Archives of Biochemistry and Biophysics. 311: 242-50. PMID 8203886 DOI: 10.1006/Abbi.1994.1233 |
0.326 |
|
| 1993 |
Hartley DP, Petersen DR. Metabolic interactions of 4-hydroxynonenal, acetaldehyde and glutathione in isolated liver mitochondria. Advances in Experimental Medicine and Biology. 328: 27-36. PMID 8493904 DOI: 10.1007/978-1-4615-2904-0_4 |
0.443 |
|
| 1991 |
Petersen DR, Hjelle JJ, Mitchell DY. Aldehydic products of lipid peroxidation: substrates or inhibitors of hepatic aldehyde dehydrogenase? Advances in Experimental Medicine and Biology. 284: 67-73. PMID 2053492 DOI: 10.1007/978-1-4684-5901-2_9 |
0.347 |
|
| 1991 |
Lindahl R, Petersen DR. Lipid aldehyde oxidation as a physiological role for class 3 aldehyde dehydrogenases Biochemical Pharmacology. 41: 1583-1587. PMID 2043148 DOI: 10.1016/0006-2952(91)90157-Z |
0.347 |
|
| 1991 |
Boyer CS, Petersen DR. Hepatic biochemical changes as a result of acute cocaine administration in the mouse Hepatology. 14: 1209-1216. DOI: 10.1002/Hep.1840140641 |
0.329 |
|
| 1990 |
Boyer CS, Petersen DR. Potentiation of cocaine-mediated hepatotoxicity by acute and chronic ethanol. Alcoholism, Clinical and Experimental Research. 14: 28-31. PMID 2178468 DOI: 10.1111/J.1530-0277.1990.Tb00441.X |
0.313 |
|
| 1989 |
Mitchell DY, Petersen DR. Oxidation of aldehydic products of lipid peroxidation by rat liver microsomal aldehyde dehydrogenase. Archives of Biochemistry and Biophysics. 269: 11-7. PMID 2916835 DOI: 10.1016/0003-9861(89)90081-7 |
0.307 |
|
| 1987 |
Mitchell DY, Petersen DR. The oxidation of alpha-beta unsaturated aldehydic products of lipid peroxidation by rat liver aldehyde dehydrogenases. Toxicology and Applied Pharmacology. 87: 403-10. PMID 3564015 DOI: 10.1016/0041-008X(87)90245-6 |
0.406 |
|
| 1984 |
Eriksson CJ, Atkinson N, Petersen DR, Deitrich RA. Blood and liver acetaldehyde concentrations during ethanol oxidation in C57 and DBA mice. Biochemical Pharmacology. 33: 2213-6. PMID 6466344 DOI: 10.1016/0006-2952(84)90656-7 |
0.347 |
|
| 1983 |
Hjelle JJ, Petersen DR. Hepatic aldehyde dehydrogenases and lipid peroxidation. Pharmacology, Biochemistry, and Behavior. 155-60. PMID 6634832 DOI: 10.1016/0091-3057(83)90164-8 |
0.31 |
|
| 1983 |
Hjelle JJ, Petersen DR. Metabolism of malondialdehyde by rat liver aldehyde dehydrogenase. Toxicology and Applied Pharmacology. 70: 57-66. PMID 6612739 DOI: 10.1016/0041-008X(83)90179-5 |
0.304 |
|
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