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Mark Spaller - Publications

Affiliations: 
Wayne State University, Detroit, MI, United States 
Area:
Biochemistry
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Omelchenko A, Menon H, Donofrio SG, Kumar G, Chapman HM, Roshal J, Martinez-Montes ER, Wang TL, Spaller MR, Firestein BL. Interaction Between CRIPT and PSD-95 Is Required for Proper Dendritic Arborization in Hippocampal Neurons. Molecular Neurobiology. PMID 32157575 DOI: 10.1007/s12035-020-01895-5  0.388
2016 Knafo S, Sánchez-Puelles C, Palomer E, Delgado I, Draffin JE, Mingo J, Wahle T, Kaleka K, Mou L, Pereda-Perez I, Klosi E, Faber EB, Chapman HM, Lozano-Montes L, Ortega-Molina A, ... ... Spaller MR, et al. PTEN recruitment controls synaptic and cognitive function in Alzheimer's models. Nature Neuroscience. PMID 26780512 DOI: 10.1038/Nn.4225  0.712
2014 Amacher JF, Zhao R, Spaller MR, Madden DR. Chemically modified peptide scaffolds target the CFTR-associated ligand PDZ domain. Plos One. 9: e103650. PMID 25136860 DOI: 10.1371/Journal.Pone.0103650  0.463
2013 Yedidi RS, Muhuhi JM, Liu Z, Bencze KZ, Koupparis K, O'Connor CE, Kovari IA, Spaller MR, Kovari LC. Design, synthesis and evaluation of a potent substrate analog inhibitor identified by scanning Ala/Phe mutagenesis, mimicking substrate co-evolution, against multidrug-resistant HIV-1 protease. Biochemical and Biophysical Research Communications. 438: 703-8. PMID 23921229 DOI: 10.1016/J.Bbrc.2013.07.117  0.747
2013 Kaur M, Rupasinghe CN, Klosi E, Spaller MR, Chow CS. Selection of heptapeptides that bind helix 69 of bacterial 23S ribosomal RNA. Bioorganic & Medicinal Chemistry. 21: 1240-7. PMID 23375098 DOI: 10.1016/J.Bmc.2012.12.048  0.783
2012 Patra CR, Rupasinghe CN, Dutta SK, Bhattacharya S, Wang E, Spaller MR, Mukhopadhyay D. Chemically modified peptides targeting the PDZ domain of GIPC as a therapeutic approach for cancer. Acs Chemical Biology. 7: 770-9. PMID 22292614 DOI: 10.1021/Cb200536R  0.369
2010 Rubini C, Ruzza P, Spaller MR, Siligardi G, Hussain R, Udugamasooriya DG, Bellanda M, Mammi S, Borgogno A, Calderan A, Cesaro L, Brunati AM, Donella-Deana A. Recognition of lysine-rich peptide ligands by murine cortactin SH3 domain: CD, ITC, and NMR studies. Biopolymers. 94: 298-306. PMID 19921743 DOI: 10.1002/bip.21350  0.783
2009 Li M, Duc AC, Klosi E, Pattabiraman S, Spaller MR, Chow CS. Selection of peptides that target the aminoacyl-tRNA site of bacterial 16S ribosomal RNA. Biochemistry. 48: 8299-311. PMID 19645415 DOI: 10.1021/Bi900982T  0.758
2009 Muders MH, Vohra PK, Dutta SK, Wang E, Ikeda Y, Wang L, Udugamasooriya DG, Memic A, Rupasinghe CN, Rupashinghe CN, Baretton GB, Aust DE, Langer S, Datta K, Simons M, ... Spaller MR, et al. Targeting GIPC/synectin in pancreatic cancer inhibits tumor growth. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 4095-103. PMID 19509165 DOI: 10.1158/1078-0432.Ccr-08-2837  0.73
2009 Sharma SC, Memic A, Rupasinghe CN, Duc AC, Spaller MR. T7 phage display as a method of peptide ligand discovery for PDZ domain proteins. Biopolymers. 92: 183-93. PMID 19235856 DOI: 10.1002/Bip.21172  0.794
2008 Memic A, Spaller MR. How do halogen substituents contribute to protein-binding interactions? A thermodynamic study of peptide ligands with diverse aryl halides. Chembiochem : a European Journal of Chemical Biology. 9: 2793-5. PMID 18985647 DOI: 10.1002/Cbic.200800572  0.709
2008 Udugamasooriya DG, Sharma SC, Spaller MR. A chemical library approach to organic-modified peptide ligands for PDZ domain proteins: a synthetic, thermodynamic and structural investigation. Chembiochem : a European Journal of Chemical Biology. 9: 1587-9. PMID 18506876 DOI: 10.1002/Cbic.200800126  0.803
2008 Udugamasooriya DG, Spaller MR. Conformational constraint in protein ligand design and the inconsistency of binding entropy. Biopolymers. 89: 653-67. PMID 18335423 DOI: 10.1002/bip.20983  0.747
2007 Sharma SC, Rupasinghe CN, Parisien RB, Spaller MR. Design, synthesis, and evaluation of linear and cyclic peptide ligands for PDZ10 of the multi-PDZ domain protein MUPP1. Biochemistry. 46: 12709-20. PMID 17939682 DOI: 10.1021/Bi7008135  0.756
2007 Klosi E, Saro D, Spaller MR. Bivalent peptides as PDZ domain ligands. Bioorganic & Medicinal Chemistry Letters. 17: 6147-50. PMID 17890086 DOI: 10.1016/J.Bmcl.2007.09.035  0.792
2007 Saro D, Li T, Rupasinghe C, Paredes A, Caspers N, Spaller MR. A thermodynamic ligand binding study of the third PDZ domain (PDZ3) from the mammalian neuronal protein PSD-95. Biochemistry. 46: 6340-52. PMID 17474715 DOI: 10.1021/Bi062088K  0.48
2006 Muhuhi J, Spaller MR. Expanding the synthetic method and structural diversity potential for the intramolecular Aza Diels-Alder cyclization. The Journal of Organic Chemistry. 71: 5515-26. PMID 16839130 DOI: 10.1021/Jo060148M  0.72
2006 Piserchio A, Spaller M, Mierke DF. Targeting the PDZ domains of molecular scaffolds of transmembrane ion channels. The Aaps Journal. 8: E396-401. PMID 16796391 DOI: 10.1007/Bf02854911  0.382
2006 Cook JD, Bencze KZ, Jankovic AD, Crater AK, Busch CN, Bradley PB, Stemmler AJ, Spaller MR, Stemmler TL. Monomeric yeast frataxin is an iron-binding protein. Biochemistry. 45: 7767-77. PMID 16784228 DOI: 10.1021/Bi060424R  0.746
2006 Spaller M, Muhuhi J. Synthesis of Tetrahydroquinolines via an Intramolecular Aza-Diels-Alder Reaction Synfacts. 2006: 1107-1107. DOI: 10.1055/s-2006-949415  0.698
2005 Udugamasooriya G, Saro D, Spaller MR. Bridged peptide macrocycles as ligands for PDZ domain proteins. Organic Letters. 7: 1203-6. PMID 15787467 DOI: 10.1021/ol0475966  0.431
2004 Ukpabi N, Sharma S, Spaller MR, Tsang P. (1)H, (15)N and (13)C backbone and side chain assignments of PSD-95 PDZ3 protein. Journal of Biomolecular Nmr. 30: 111-2. PMID 15452444 DOI: 10.1023/B:Jnmr.0000042953.83397.8E  0.613
2004 Saro D, Klosi E, Paredes A, Spaller MR. Thermodynamic analysis of a hydrophobic binding site: probing the PDZ domain with nonproteinogenic peptide ligands. Organic Letters. 6: 3429-32. PMID 15387515 DOI: 10.1021/Ol049181Q  0.797
2004 Piserchio A, Salinas GD, Li T, Marshall J, Spaller MR, Mierke DF. Targeting specific PDZ domains of PSD-95; structural basis for enhanced affinity and enzymatic stability of a cyclic peptide. Chemistry & Biology. 11: 469-73. PMID 15123241 DOI: 10.1016/J.Chembiol.2004.03.013  0.437
2004 Li T, Saro D, Spaller MR. Thermodynamic profiling of conformationally constrained cyclic ligands for the PDZ domain. Bioorganic & Medicinal Chemistry Letters. 14: 1385-8. PMID 15006367 DOI: 10.1016/j.bmcl.2003.09.103  0.442
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