Nancy Maizels - Publications

University of Washington, Seattle, Seattle, WA 

91 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Nitiss JL, Kiianitsa K, Sun Y, Nitiss KC, Maizels N. Topoisomerase Assays. Current Protocols. 1: e250. PMID 34606690 DOI: 10.1002/cpz1.250  1
2021 Zhang Y, Davis L, Maizels N. Pathways and signatures of mutagenesis at targeted DNA nicks. Plos Genetics. 17: e1009329. PMID 33857147 DOI: 10.1371/journal.pgen.1009329  1
2020 Kiianitsa K, Zhang Y, Maizels N. Treatment of human cells with 5-aza-dC induces formation of PARP1-DNA covalent adducts at genomic regions targeted by DNMT1. Dna Repair. 96: 102977. PMID 33039802 DOI: 10.1016/j.dnarep.2020.102977  1
2020 Davis L, Khoo KJ, Zhang Y, Maizels N. POLQ suppresses interhomolog recombination and loss of heterozygosity at targeted DNA breaks. Proceedings of the National Academy of Sciences of the United States of America. PMID 32873648 DOI: 10.1073/Pnas.2008073117  1
2020 Sinha D, Kiianitsa K, Sherman DR, Maizels N. Rapid, direct detection of bacterial Topoisomerase 1-DNA adducts by RADAR/ELISA. Analytical Biochemistry. 113827. PMID 32738213 DOI: 10.1016/J.Ab.2020.113827  1
2020 Kiianitsa K, Maizels N. The "adductome": A limited repertoire of adducted proteins in human cells. Dna Repair. 89: 102825. PMID 32109764 DOI: 10.1016/J.Dnarep.2020.102825  1
2019 Gray LT, Puig Lombardi E, Verga D, Nicolas A, Teulade-Fichou MP, Londoño-Vallejo A, Maizels N. G-quadruplexes Sequester Free Heme in Living Cells. Cell Chemical Biology. PMID 31668518 DOI: 10.1016/J.Chembiol.2019.10.003  1
2019 Le Q, Maizels N. Activation-induced deaminase (AID) localizes to the nucleus in brief pulses. Plos Genetics. 15: e1007968. PMID 30811383 DOI: 10.1371/Journal.Pgen.1007968  1
2018 Olson HC, Davis L, Kiianitsa K, Khoo KJ, Liu Y, Knijnenburg TA, Maizels N. Increased levels of RECQ5 shift DNA repair from canonical to alternative pathways. Nucleic Acids Research. PMID 30107528 DOI: 10.1093/Nar/Gky727  1
2018 Maizels N, Davis L. Initiation of homologous recombination at DNA nicks. Nucleic Acids Research. PMID 29986051 DOI: 10.1093/Nar/Gky588  1
2018 Davis L, Zhang Y, Maizels N. Assaying Repair at DNA Nicks. Methods in Enzymology. 601: 71-89. PMID 29523243 DOI: 10.1016/Bs.Mie.2017.12.001  1
2016 Davis L, Maizels N. Two Distinct Pathways Support Gene Correction by Single-Stranded Donors at DNA Nicks. Cell Reports. 17: 1872-1881. PMID 27829157 DOI: 10.1016/J.Celrep.2016.10.049  1
2016 Tang W, Robles AI, Beyer RP, Gray LT, Nguyen GH, Oshima J, Maizels N, Harris CC, Monnat RJ. The Werner syndrome RECQ helicase targets G4 DNA in human cells to modulate transcription. Human Molecular Genetics. PMID 26984941 DOI: 10.1093/Hmg/Ddw079  1
2015 Le Q, Maizels N. Cell Cycle Regulates Nuclear Stability of AID and Determines the Cellular Response to AID. Plos Genetics. 11: e1005411. PMID 26355458 DOI: 10.1371/Journal.Pgen.1005411  1
2015 Maizels N. G4-associated human diseases. Embo Reports. 16: 910-22. PMID 26150098 DOI: 10.15252/Embr.201540607  0.01
2014 Pavelitz T, Renfro L, Foster NR, Caracol A, Welsch P, Lao VV, Grady WB, Niedzwiecki D, Saltz LB, Bertagnolli MM, Goldberg RM, Rabinovitch PS, Emond M, Monnat RJ, Maizels N. MRE11-deficiency associated with improved long-term disease free survival and overall survival in a subset of stage III colon cancer patients in randomized CALGB 89803 trial. Plos One. 9: e108483. PMID 25310185 DOI: 10.1371/Journal.Pone.0108483  1
2014 Nguyen GH, Tang W, Robles AI, Beyer RP, Gray LT, Welsh JA, Schetter AJ, Kumamoto K, Wang XW, Hickson ID, Maizels N, Monnat RJ, Harris CC. Regulation of gene expression by the BLM helicase correlates with the presence of G-quadruplex DNA motifs. Proceedings of the National Academy of Sciences of the United States of America. 111: 9905-10. PMID 24958861 DOI: 10.1073/Pnas.1404807111  1
2014 Kiianitsa K, Maizels N. Ultrasensitive isolation, identification and quantification of DNA-protein adducts by ELISA-based RADAR assay. Nucleic Acids Research. 42: e108. PMID 24914050 DOI: 10.1093/Nar/Gku490  1
2014 Shiovitz S, Bertagnolli MM, Renfro LA, Nam E, Foster NR, Dzieciatkowski S, Luo Y, Lao VV, Monnat RJ, Emond MJ, Maizels N, Niedzwiecki D, Goldberg RM, Saltz LB, Venook A, et al. CpG island methylator phenotype is associated with response to adjuvant irinotecan-based therapy for stage III colon cancer. Gastroenterology. 147: 637-45. PMID 24859205 DOI: 10.1053/J.Gastro.2014.05.009  1
2014 Gray LT, Vallur AC, Eddy J, Maizels N. G quadruplexes are genomewide targets of transcriptional helicases XPB and XPD. Nature Chemical Biology. 10: 313-8. PMID 24609361 DOI: 10.1038/Nchembio.1475  1
2014 Davis L, Maizels N. Homology-directed repair of DNA nicks via pathways distinct from canonical double-strand break repair. Proceedings of the National Academy of Sciences of the United States of America. 111: E924-32. PMID 24556991 DOI: 10.1073/Pnas.1400236111  1
2014 Kuhar R, Gwiazda KS, Humbert O, Mandt T, Pangallo J, Brault M, Khan I, Maizels N, Rawlings DJ, Scharenberg AM, Certo MT. Novel fluorescent genome editing reporters for monitoring DNA repair pathway utilization at endonuclease-induced breaks. Nucleic Acids Research. 42: e4. PMID 24121685 DOI: 10.1093/Nar/Gkt872  1
2013 Maizels N. Genome engineering with Cre-loxP. Journal of Immunology (Baltimore, Md. : 1950). 191: 5-6. PMID 23794700 DOI: 10.4049/Jimmunol.1301241  0.01
2013 Maizels N, Lupski JR. Molecular and genetic bases of disease. Current Opinion in Genetics & Development. 23: 229-31. PMID 23790955 DOI: 10.1016/J.Gde.2013.05.006  0.01
2013 Maizels N, Gray LT. The G4 genome. Plos Genetics. 9: e1003468. PMID 23637633 DOI: 10.1371/Journal.Pgen.1003468  1
2013 Kiianitsa K, Maizels N. A rapid and sensitive assay for DNA-protein covalent complexes in living cells. Nucleic Acids Research. 41: e104. PMID 23519618 DOI: 10.1093/Nar/Gkt171  1
2012 Humbert O, Maizels N. Epigenetic modification of the repair donor regulates targeted gene correction. Molecular Therapy. Nucleic Acids. 1: e49. PMID 23344649 DOI: 10.1038/Mtna.2012.42  1
2012 Maizels N. G4 motifs in human genes. Annals of the New York Academy of Sciences. 1267: 53-60. PMID 22954217 DOI: 10.1111/J.1749-6632.2012.06586.X  0.01
2012 Yabuki M, Cummings WJ, Leppard JB, Immormino RM, Wood CL, Allison DS, Gray PW, Tjoelker LW, Maizels N. Antibody discovery ex vivo accelerated by the LacO/LacI regulatory network. Plos One. 7: e36032. PMID 22558313 DOI: 10.1371/Journal.Pone.0036032  1
2012 Humbert O, Davis L, Maizels N. Targeted gene therapies: tools, applications, optimization. Critical Reviews in Biochemistry and Molecular Biology. 47: 264-81. PMID 22530743 DOI: 10.3109/10409238.2012.658112  1
2011 Sacho EJ, Maizels N. DNA repair factor MRE11/RAD50 cleaves 3'-phosphotyrosyl bonds and resects DNA to repair damage caused by topoisomerase 1 poisons. The Journal of Biological Chemistry. 286: 44945-51. PMID 22039049 DOI: 10.1074/Jbc.M111.299347  1
2011 Davis L, Maizels N. G4 DNA: at risk in the genome. The Embo Journal. 30: 3878-9. PMID 21975374 DOI: 10.1038/Emboj.2011.342  1
2011 Davis L, Maizels N. DNA nicks promote efficient and safe targeted gene correction. Plos One. 6: e23981. PMID 21912657 DOI: 10.1371/Journal.Pone.0023981  1
2011 Eddy J, Vallur AC, Varma S, Liu H, Reinhold WC, Pommier Y, Maizels N. G4 motifs correlate with promoter-proximal transcriptional pausing in human genes. Nucleic Acids Research. 39: 4975-83. PMID 21371997 DOI: 10.1093/Nar/Gkr079  1
2010 Hamilton NK, Maizels N. MRE11 function in response to topoisomerase poisons is independent of its function in double-strand break repair in Saccharomyces cerevisiae. Plos One. 5: e15387. PMID 21060845 DOI: 10.1371/Journal.Pone.0015387  0.01
2010 Vallur AC, Maizels N. Complementary roles for exonuclease 1 and Flap endonuclease 1 in maintenance of triplet repeats. The Journal of Biological Chemistry. 285: 28514-9. PMID 20643645 DOI: 10.1074/Jbc.M110.132738  1
2010 Vallur AC, Maizels N. Distinct activities of exonuclease 1 and flap endonuclease 1 at telomeric g4 DNA. Plos One. 5: e8908. PMID 20126648 DOI: 10.1371/Journal.Pone.0008908  1
2009 Ordinario EC, Yabuki M, Handa P, Cummings WJ, Maizels N. RAD51 paralogs promote homology-directed repair at diversifying immunoglobulin V regions. Bmc Molecular Biology. 10: 98. PMID 19863810 DOI: 10.1186/1471-2199-10-98  1
2009 Ordinario EC, Yabuki M, Larson RP, Maizels N. Temporal regulation of Ig gene diversification revealed by single-cell imaging. Journal of Immunology (Baltimore, Md. : 1950). 183: 4545-53. PMID 19748985 DOI: 10.4049/Jimmunol.0900673  1
2009 Eddy J, Maizels N. Selection for the G4 DNA motif at the 5' end of human genes. Molecular Carcinogenesis. 48: 319-25. PMID 19306310 DOI: 10.1002/Mc.20496  1
2009 McConnell Smith A, Takeuchi R, Pellenz S, Davis L, Maizels N, Monnat RJ, Stoddard BL. Generation of a nicking enzyme that stimulates site-specific gene conversion from the I-AniI LAGLIDADG homing endonuclease. Proceedings of the National Academy of Sciences of the United States of America. 106: 5099-104. PMID 19276110 DOI: 10.1073/Pnas.0810588106  1
2009 Yabuki M, Ordinario EC, Cummings WJ, Fujii MM, Maizels N. E2A acts in cis in G1 phase of cell cycle to promote Ig gene diversification. Journal of Immunology (Baltimore, Md. : 1950). 182: 408-15. PMID 19109172 DOI: 10.4049/Jimmunol.182.1.408  1
2008 Cummings WJ, Bednarski DW, Maizels N. Genetic variation stimulated by epigenetic modification. Plos One. 3: e4075. PMID 19115012 DOI: 10.1371/Journal.Pone.0004075  1
2008 Larson ED, Bednarski DW, Maizels N. High-fidelity correction of genomic uracil by human mismatch repair activities. Bmc Molecular Biology. 9: 94. PMID 18954457 DOI: 10.1186/1471-2199-9-94  1
2008 Vallur AC, Maizels N. Activities of human exonuclease 1 that promote cleavage of transcribed immunoglobulin switch regions. Proceedings of the National Academy of Sciences of the United States of America. 105: 16508-12. PMID 18940926 DOI: 10.1073/Pnas.0805327105  1
2008 Maizels N. Genomic stability: FANCJ-dependent G4 DNA repair. Current Biology : Cb. 18: R613-4. PMID 18644339 DOI: 10.1016/J.Cub.2008.06.011  0.01
2008 Eddy J, Maizels N. Conserved elements with potential to form polymorphic G-quadruplex structures in the first intron of human genes. Nucleic Acids Research. 36: 1321-33. PMID 18187510 DOI: 10.1093/Nar/Gkm1138  1
2007 Cummings WJ, Yabuki M, Ordinario EC, Bednarski DW, Quay S, Maizels N. Chromatin structure regulates gene conversion. Plos Biology. 5: e246. PMID 17880262 DOI: 10.1371/Journal.Pbio.0050246  1
2007 Duquette ML, Huber MD, Maizels N. G-rich proto-oncogenes are targeted for genomic instability in B-cell lymphomas. Cancer Research. 67: 2586-94. PMID 17363577 DOI: 10.1158/0008-5472.Can-06-2419  1
2006 Maizels N. Dynamic roles for G4 DNA in the biology of eukaryotic cells. Nature Structural & Molecular Biology. 13: 1055-9. PMID 17146462 DOI: 10.1038/Nsmb1171  0.01
2006 Eddy J, Maizels N. Gene function correlates with potential for G4 DNA formation in the human genome. Nucleic Acids Research. 34: 3887-96. PMID 16914419 DOI: 10.1093/Nar/Gkl529  1
2006 Huber MD, Duquette ML, Shiels JC, Maizels N. A conserved G4 DNA binding domain in RecQ family helicases. Journal of Molecular Biology. 358: 1071-80. PMID 16530788 DOI: 10.1016/J.Jmb.2006.01.077  1
2005 Larson ED, Cummings WJ, Bednarski DW, Maizels N. MRE11/RAD50 cleaves DNA in the AID/UNG-dependent pathway of immunoglobulin gene diversification. Molecular Cell. 20: 367-75. PMID 16285919 DOI: 10.1016/J.Molcel.2005.09.018  1
2005 Maizels N. Immunoglobulin gene diversification. Annual Review of Genetics. 39: 23-46. PMID 16285851 DOI: 10.1146/Annurev.Genet.39.073003.110544  0.01
2005 Duquette ML, Pham P, Goodman MF, Maizels N. AID binds to transcription-induced structures in c-MYC that map to regions associated with translocation and hypermutation. Oncogene. 24: 5791-8. PMID 15940261 DOI: 10.1038/Sj.Onc.1208746  1
2005 Yabuki M, Fujii MM, Maizels N. The MRE11-RAD50-NBS1 complex accelerates somatic hypermutation and gene conversion of immunoglobulin variable regions. Nature Immunology. 6: 730-6. PMID 15937485 DOI: 10.1038/Ni1215  1
2005 Larson ED, Duquette ML, Cummings WJ, Streiff RJ, Maizels N. MutSalpha binds to and promotes synapsis of transcriptionally activated immunoglobulin switch regions. Current Biology : Cb. 15: 470-4. PMID 15753043 DOI: 10.1016/J.Cub.2004.12.077  1
2004 Duquette ML, Handa P, Vincent JA, Taylor AF, Maizels N. Intracellular transcription of G-rich DNAs induces formation of G-loops, novel structures containing G4 DNA. Genes & Development. 18: 1618-29. PMID 15231739 DOI: 10.1101/Gad.1200804  1
2004 Larson ED, Maizels N. Transcription-coupled mutagenesis by the DNA deaminase AID. Genome Biology. 5: 211. PMID 15003109 DOI: 10.1186/Gb-2004-5-3-211  1
2003 Cocco MJ, Hanakahi LA, Huber MD, Maizels N. Specific interactions of distamycin with G-quadruplex DNA. Nucleic Acids Research. 31: 2944-51. PMID 12771220 DOI: 10.1093/Nar/Gkg392  1
2003 Maizels N. Yin outwits Yang at the IgE locus. Nature Immunology. 4: 7-8. PMID 12496968 DOI: 10.1038/Ni0103-7  0.01
2003 Maizels N, Scharff MD. Molecular Mechanism of Hypermutation Molecular Biology of B Cells. 327-338. DOI: 10.1016/B978-012053641-2/50022-8  1
2002 Huber MD, Lee DC, Maizels N. G4 DNA unwinding by BLM and Sgs1p: substrate specificity and substrate-specific inhibition. Nucleic Acids Research. 30: 3954-61. PMID 12235379 DOI: 10.1093/Nar/Gkf530  1
2001 Liu Y, Maizels N. Coordinated response of mammalian Rad51 and Rad52 to DNA damage. Embo Reports. 1: 85-90. PMID 11256631 DOI: 10.1093/Embo-Reports/Kvd002  0.4
2001 Kong Q, Maizels N. Breaksite batch mapping, a rapid method for assay and identification of DNA breaksites in mammalian cells Nucleic Acids Research. 29: E33. PMID 11239010 DOI: 10.1093/Nar/29.6.E33  1
2000 Gallouzi IE, Brennan CM, Stenberg MG, Swanson MS, Eversole A, Maizels N, Steitz JA. HuR binding to cytoplasmic mRNA is perturbed by heat shock. Proceedings of the National Academy of Sciences of the United States of America. 97: 3073-8. PMID 10737787 DOI: 10.1073/Pnas.97.7.3073  1
1999 Maizels N, Weiner AM, Yue D, Shi PY. New evidence for the genomic tag hypothesis: Archaeal CCA-adding enzymes and tDNA substrates Biological Bulletin. 196: 331-334. PMID 10390831 DOI: 10.2307/1542963  1
1999 Weiner AM, Maizels N. The genomic tag hypothesis: Modern viruses as molecular fossils of ancient strategies for genomic replication, and clues regarding the origin of protein synthesis Biological Bulletin. 196: 327-330. PMID 10390830 DOI: 10.2307/1542962  1
1999 Kong Q, Maizels N. PMS2-deficiency diminishes hypermutation of a λ1 transgene in young but not older mice Molecular Immunology. 36: 83-91. PMID 10378680 DOI: 10.1016/S0161-5890(99)00027-9  1
1999 Weiner AM, Maizels N. A deadly double life Science. 284: 63-64. PMID 10215533 DOI: 10.1126/Science.284.5411.63  1
1999 Maizels N, Weiner AM. 3 The Genomic Tag Hypothesis: What Molecular Fossils Tell Us about the Evolution of tRNA Cold Spring Harbor Monograph Archive. 37: 79-111. DOI: 10.1101/087969589.37.79  1
1998 Yue D, Weiner AM, Maizels N. The CCA-adding enzyme has a single active site Journal of Biological Chemistry. 273: 29693-29700. PMID 9792681 DOI: 10.1074/Jbc.273.45.29693  1
1998 Dempsey LA, Li MJ, DePace A, Bray-Ward P, Maizels N. The human HNRPD locus maps to 4q21 and encodes a highly conserved protein. Genomics. 49: 378-84. PMID 9615222 DOI: 10.1006/Geno.1998.5237  1
1998 Shi PY, Maizels N, Weiner AM. CCA addition by tRNA nucleotidyltransferase: Polymerization without translocation? Embo Journal. 17: 3197-3206. PMID 9606201 DOI: 10.1093/Emboj/17.11.3197  1
1998 Kong Q, Harris RS, Maizels N. Recombination-based mechanisms for somatic hypermutation Immunological Reviews. 162: 67-76. PMID 9602353 DOI: 10.1111/J.1600-065X.1998.Tb01430.X  1
1997 Ashburner M, Maizels N. Genomes and evolution Post-genome, pre-chromosome. Current Opinion in Genetics & Development. 7: 747-9. PMID 9471993 DOI: 10.1016/S0959-437X(97)80035-4  1
1997 Shi PY, Maizels N, Weiner AM. Recovery of soluble, active recombinant protein from inclusion bodies Biotechniques. 23: 1036-1038. PMID 9421633 DOI: 10.2144/97236Bm15  1
1996 Li MJ, Peakman MC, Golub EI, Reddy G, Ward DC, Radding CM, Maizels N. Rad51 expression and localization in B cells carrying out class switch recombination. Proceedings of the National Academy of Sciences of the United States of America. 93: 10222-7. PMID 8816780 DOI: 10.1073/Pnas.93.19.10222  1
1994 Maizels N, Weiner AM. Phylogeny from function: Evidence from the molecular fossil record that tRNA originated in replication, not translation Proceedings of the National Academy of Sciences of the United States of America. 91: 6729-6734. PMID 8041690 DOI: 10.1073/Pnas.91.15.6729  1
1994 Weiner AM, Maizels N. Molecular Evolution: Unlocking the secrets of retroviral evolution Current Biology. 4: 560-563. PMID 7522918 DOI: 10.1016/S0960-9822(00)00126-3  1
1993 Maizels N, Weiner AM. 23 The Genomic Tag Hypothesis: Modern Viruses as Molecular Fossils of Ancient Strategies for Genomic Replication Cold Spring Harbor Monograph Archive. 24: 577-602. DOI: 10.1101/087969380.24.577  1
1992 Williams M, Brys A, Weiner AM, Maizels N. A rapid method for determining the molecular weight of a protein bound to nucleic acid in a mobility shift assay Nucleic Acids Research. 20: 4935-4936. PMID 1408813 DOI: 10.1093/Nar/20.18.4935  1
1991 Maizels N, Zimmer E. Gene organization and evolution Current Opinion in Genetics and Development. 1: 447-450. DOI: 10.1016/S0959-437X(05)80190-X  1
1990 Weiner AM, Maizels N. RNA editing: Guided but not templated? Cell. 61: 917-920. PMID 1693547 DOI: 10.1016/0092-8674(90)90053-H  1
1989 Maizels N, Lau JC, Blier PR, Bothwell A. The T-cell independent antigen, NP-ficoll, primes for a high affinity IgM anti-NP response. Molecular Immunology. 25: 1277-82. PMID 3070356 DOI: 10.1016/0161-5890(88)90042-9  0.4
1988 Maizels N, Weiner A. In search of a template Nature. 334: 469-470. PMID 2457168 DOI: 10.1038/334469A0  1
1987 Weiner AM, Maizels N. tRNA-like structures tag the 3' ends of genomic RNA molecules for replication: implications for the origin of protein synthesis Proceedings of the National Academy of Sciences of the United States of America. 84: 7383-7387. PMID 3478699 DOI: 10.1073/Pnas.84.21.7383  1
1987 Maizels N, Weiner AM. Peptide-specific ribosomes, genomic tags, and the origin of the genetic code Cold Spring Harbor Symposia On Quantitative Biology. 52: 743-749. PMID 3454285 DOI: 10.1101/SQB.1987.052.01.083  1
1987 Maizels N, Weiner AM. The 'last ribo-organism' was no breakthrough [7] Nature. 330: 616. PMID 2446146 DOI: 10.1038/330616A0  1
1980 Grainger RM, Maizels N. Dictyostelium ribosomal RNA is processed during transcription Cell. 20: 619-623. PMID 7418001 DOI: 10.1016/0092-8674(80)90308-6  1
1974 Gilbert W, Maizels N, Maxam A. Sequences of controlling regions of the lactose operon. Cold Spring Harbor Symposia On Quantitative Biology. 38: 845-55. PMID 4598642 DOI: 10.1101/Sqb.1974.038.01.087  0.04
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