Janos Zempleni - Publications

Affiliations: 
The University of Nebraska - Lincoln, Lincoln, NE 
Area:
Biochemistry

103 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Camara Teixeira D, Cordonier EL, Wijeratne SSK, Huebbe P, Jamin A, Jarecke S, Wiebe M, Zempleni J. A cell death assay for assessing the mitochondrial targeting of proteins. The Journal of Nutritional Biochemistry. 56: 48-54. PMID 29454998 DOI: 10.1016/j.jnutbio.2018.01.006  0.64
2016 Cordonier EL, Jarecke SK, Hollinger FE, Zempleni J. Inhibition of acetyl-CoA carboxylases by soraphen A prevents lipid accumulation and adipocyte differentiation in 3T3-L1 cells. European Journal of Pharmacology. PMID 27041646 DOI: 10.1016/j.ejphar.2016.03.052  0.32
2015 Shu J, Chiang K, Zempleni J, Cui J. Computational Characterization of Exogenous MicroRNAs that Can Be Transferred into Human Circulation. Plos One. 10: e0140587. PMID 26528912 DOI: 10.1371/journal.pone.0140587  0.76
2015 Kelly AM, Plautz SA, Zempleni J, Pannier AK. Glucocorticoid Cell Priming Enhances Transfection Outcomes in Adult Human Mesenchymal Stem Cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26478250 DOI: 10.1038/mt.2015.195  0.76
2015 Zempleni J, Baier SR, Hirschi K. Diet-responsive MicroRNAs Are Likely Exogenous. The Journal of Biological Chemistry. 290: 25197. PMID 26453700 DOI: 10.1074/jbc.L115.687830  0.76
2015 Cordonier EL, Adjam R, Teixeira DC, Onur S, Zbasnik R, Read PE, Döring F, Schlegel VL, Zempleni J. Resveratrol compounds inhibit human holocarboxylase synthetase and cause a lean phenotype in Drosophila melanogaster. The Journal of Nutritional Biochemistry. 26: 1379-84. PMID 26303405 DOI: 10.1016/j.jnutbio.2015.07.004  0.76
2015 Wolf T, Baier SR, Zempleni J. The Intestinal Transport of Bovine Milk Exosomes Is Mediated by Endocytosis in Human Colon Carcinoma Caco-2 Cells and Rat Small Intestinal IEC-6 Cells. The Journal of Nutrition. 145: 2201-6. PMID 26269243 DOI: 10.3945/jn.115.218586  0.76
2015 Zempleni J, Baier SR, Howard KM, Cui J. Gene regulation by dietary microRNAs. Canadian Journal of Physiology and Pharmacology. 1-6. PMID 26222444 DOI: 10.1139/cjpp-2014-0392  0.76
2015 Chiang K, Shu J, Zempleni J, Cui J. Dietary MicroRNA Database (DMD): An Archive Database and Analytic Tool for Food-Borne microRNAs. Plos One. 10: e0128089. PMID 26030752 DOI: 10.1371/journal.pone.0128089  0.76
2015 Howard KM, Jati Kusuma R, Baier SR, Friemel T, Markham L, Vanamala J, Zempleni J. Loss of miRNAs during processing and storage of cow's (Bos taurus) milk. Journal of Agricultural and Food Chemistry. 63: 588-92. PMID 25565082 DOI: 10.1021/jf505526w  0.76
2014 Sittiwong W, Cordonier EL, Zempleni J, Dussault PH. β-Keto and β-hydroxyphosphonate analogs of biotin-5'-AMP are inhibitors of holocarboxylase synthetase. Bioorganic & Medicinal Chemistry Letters. 24: 5568-71. PMID 25466176 DOI: 10.1016/j.bmcl.2014.11.010  0.32
2014 Baier SR, Xie F, Zempleni J. Reply to Witwer. The Journal of Nutrition. 144: 1882. PMID 25332489 DOI: 10.3945/jn.114.202606  0.76
2014 Baier SR, Nguyen C, Xie F, Wood JR, Zempleni J. MicroRNAs are absorbed in biologically meaningful amounts from nutritionally relevant doses of cow milk and affect gene expression in peripheral blood mononuclear cells, HEK-293 kidney cell cultures, and mouse livers. The Journal of Nutrition. 144: 1495-500. PMID 25122645 DOI: 10.3945/jn.114.196436  0.76
2014 Romagnolo DF, Zempleni J, Selmin OI. Nuclear receptors and epigenetic regulation: opportunities for nutritional targeting and disease prevention. Advances in Nutrition (Bethesda, Md.). 5: 373-85. PMID 25022987 DOI: 10.3945/an.114.005868  0.76
2014 Baier SR, Zbasnik R, Schlegel V, Zempleni J. Off-target effects of sulforaphane include the derepression of long terminal repeats through histone acetylation events. The Journal of Nutritional Biochemistry. 25: 665-8. PMID 24746830 DOI: 10.1016/j.jnutbio.2014.02.007  0.76
2014 Zempleni J, Liu D, Camara DT, Cordonier EL. Novel roles of holocarboxylase synthetase in gene regulation and intermediary metabolism. Nutrition Reviews. 72: 369-76. PMID 24684412 DOI: 10.1111/nure.12103  0.32
2014 Li Y, Malkaram SA, Zhou J, Zempleni J. Lysine biotinylation and methionine oxidation in the heat shock protein HSP60 synergize in the elimination of reactive oxygen species in human cell cultures. The Journal of Nutritional Biochemistry. 25: 475-82. PMID 24582286 DOI: 10.1016/j.jnutbio.2013.12.008  0.64
2013 Xia M, Malkaram SA, Zempleni J. Three promoters regulate the transcriptional activity of the human holocarboxylase synthetase gene. The Journal of Nutritional Biochemistry. 24: 1963-9. PMID 24075901 DOI: 10.1016/j.jnutbio.2013.06.007  0.64
2013 Xue J, Wijeratne SS, Zempleni J. Holocarboxylase synthetase synergizes with methyl CpG binding protein 2 and DNA methyltransferase 1 in the transcriptional repression of long-terminal repeats. Epigenetics. 8: 504-11. PMID 23624957 DOI: 10.4161/epi.24449  0.8
2013 Li Y, Hassan YI, Moriyama H, Zempleni J. Holocarboxylase synthetase interacts physically with euchromatic histone-lysine N-methyltransferase, linking histone biotinylation with methylation events. The Journal of Nutritional Biochemistry. 24: 1446-52. PMID 23337344 DOI: 10.1016/j.jnutbio.2012.12.003  1
2013 Eng WK, Giraud D, Schlegel VL, Wang D, Lee BH, Zempleni J. Identification and assessment of markers of biotin status in healthy adults. The British Journal of Nutrition. 110: 321-9. PMID 23302490 DOI: 10.1017/S0007114512005065  0.76
2013 Camara Teixeira D, Malkaram SA, Zempleni J. Enrichment of meiotic recombination hotspot sequences by avidin capture technology. Gene. 516: 101-6. PMID 23270922 DOI: 10.1016/j.gene.2012.12.042  0.64
2013 Singh MP, Wijeratne SS, Zempleni J. Biotinylation of lysine 16 in histone H4 contributes toward nucleosome condensation. Archives of Biochemistry and Biophysics. 529: 105-11. PMID 23219734 DOI: 10.1016/j.abb.2012.11.005  0.8
2012 Malkaram SA, Hassan YI, Zempleni J. Online tools for bioinformatics analyses in nutrition sciences. Advances in Nutrition (Bethesda, Md.). 3: 654-65. PMID 22983844 DOI: 10.3945/an.112.002477  1
2012 Rios-Avila L, Pestinger V, Zempleni J. K16-biotinylated histone H4 is overrepresented in repeat regions and participates in the repression of transcriptionally competent genes in human Jurkat lymphoid cells. The Journal of Nutritional Biochemistry. 23: 1559-64. PMID 22192339 DOI: 10.1016/j.jnutbio.2011.10.009  0.56
2012 Esaki S, Malkaram SA, Zempleni J. Effects of single-nucleotide polymorphisms in the human holocarboxylase synthetase gene on enzyme catalysis. European Journal of Human Genetics : Ejhg. 20: 428-33. PMID 22027809 DOI: 10.1038/ejhg.2011.198  0.64
2012 Zempleni J, Teixeira DC, Kuroishi T, Cordonier EL, Baier S. Biotin requirements for DNA damage prevention. Mutation Research. 733: 58-60. PMID 21871906 DOI: 10.1016/j.mrfmmm.2011.08.001  0.76
2012 Bao B, Rodriguez-Melendez R, Zempleni J. Cytosine methylation in miR-153 gene promoters increases the expression of holocarboxylase synthetase, thereby increasing the abundance of histone H4 biotinylation marks in HEK-293 human kidney cells. The Journal of Nutritional Biochemistry. 23: 635-9. PMID 21764280 DOI: 10.1016/j.jnutbio.2011.03.007  0.56
2011 Kuroishi T, Rios-Avila L, Pestinger V, Wijeratne SS, Zempleni J. Biotinylation is a natural, albeit rare, modification of human histones. Molecular Genetics and Metabolism. 104: 537-45. PMID 21930408 DOI: 10.1016/j.ymgme.2011.08.030  0.8
2011 Bao B, Wijeratne SS, Rodriguez-Melendez R, Zempleni J. Human holocarboxylase synthetase with a start site at methionine-58 is the predominant nuclear variant of this protein and has catalytic activity. Biochemical and Biophysical Research Communications. 412: 115-20. PMID 21802411 DOI: 10.1016/j.bbrc.2011.07.055  0.8
2011 Zempleni J, Li Y, Xue J, Cordonier EL. The role of holocarboxylase synthetase in genome stability is mediated partly by epigenomic synergies between methylation and biotinylation events. Epigenetics. 6: 892-4. PMID 21555910  0.32
2011 Singh D, Pannier AK, Zempleni J. Identification of holocarboxylase synthetase chromatin binding sites in human mammary cell lines using the DNA adenine methyltransferase identification technology. Analytical Biochemistry. 413: 55-9. PMID 21303649 DOI: 10.1016/j.ab.2011.02.001  0.76
2011 Filenko NA, Kolar C, West JT, Smith SA, Hassan YI, Borgstahl GE, Zempleni J, Lyubchenko YL. The role of histone H4 biotinylation in the structure of nucleosomes. Plos One. 6: e16299. PMID 21298003 DOI: 10.1371/journal.pone.0016299  0.76
2011 Rios-Avila L, Prince SA, Wijeratne SS, Zempleni J. A 96-well plate assay for high-throughput analysis of holocarboxylase synthetase activity. Clinica Chimica Acta; International Journal of Clinical Chemistry. 412: 735-9. PMID 21195703 DOI: 10.1016/j.cca.2010.12.031  0.8
2011 Pestinger V, Wijeratne SS, Rodriguez-Melendez R, Zempleni J. Novel histone biotinylation marks are enriched in repeat regions and participate in repression of transcriptionally competent genes. The Journal of Nutritional Biochemistry. 22: 328-33. PMID 20691578 DOI: 10.1016/j.jnutbio.2010.02.011  0.8
2011 Bao B, Pestinger V, Hassan YI, Borgstahl GE, Kolar C, Zempleni J. Holocarboxylase synthetase is a chromatin protein and interacts directly with histone H3 to mediate biotinylation of K9 and K18. The Journal of Nutritional Biochemistry. 22: 470-5. PMID 20688500 DOI: 10.1016/j.jnutbio.2010.04.001  0.76
2010 Bao B, Rodriguez-Melendez R, Wijeratne SS, Zempleni J. Biotin regulates the expression of holocarboxylase synthetase in the miR-539 pathway in HEK-293 cells. The Journal of Nutrition. 140: 1546-51. PMID 20592104 DOI: 10.3945/jn.110.126359  0.8
2010 Mall GK, Chew YC, Zempleni J. Biotin requirements are lower in human Jurkat lymphoid cells but homeostatic mechanisms are similar to those of HepG2 liver cells. The Journal of Nutrition. 140: 1086-92. PMID 20357078 DOI: 10.3945/jn.110.121475  1
2010 Hassan YI, Moriyama H, Zempleni J. The polypeptide Syn67 interacts physically with human holocarboxylase synthetase, but is not a target for biotinylation. Archives of Biochemistry and Biophysics. 495: 35-41. PMID 20026029 DOI: 10.1016/j.abb.2009.12.017  1
2010 Wijeratne SS, Camporeale G, Zempleni J. K12-biotinylated histone H4 is enriched in telomeric repeats from human lung IMR-90 fibroblasts. The Journal of Nutritional Biochemistry. 21: 310-6. PMID 19369050 DOI: 10.1016/j.jnutbio.2009.01.010  1
2009 Zempleni J, Chew YC, Bao B, Pestinger V, Wijeratne SS. Repression of transposable elements by histone biotinylation. The Journal of Nutrition. 139: 2389-92. PMID 19812216 DOI: 10.3945/jn.109.111856  1
2009 Zempleni J, Wijeratne SS, Hassan YI. Biotin. Biofactors (Oxford, England). 35: 36-46. PMID 19319844 DOI: 10.1002/biof.8  1
2009 Hassan YI, Moriyama H, Olsen LJ, Bi X, Zempleni J. N- and C-terminal domains in human holocarboxylase synthetase participate in substrate recognition. Molecular Genetics and Metabolism. 96: 183-8. PMID 19157941 DOI: 10.1016/j.ymgme.2008.12.006  1
2009 Rodriguez-Melendez R, Zempleni J. Nitric oxide signaling depends on biotin in Jurkat human lymphoma cells. The Journal of Nutrition. 139: 429-33. PMID 19141704 DOI: 10.3945/jn.108.101840  0.4
2009 Zempleni J, Gralla M, Camporeale G, Hassan YI. Sodium-dependent multivitamin transporter gene is regulated at the chromatin level by histone biotinylation in human Jurkat lymphoblastoma cells. The Journal of Nutrition. 139: 163-6. PMID 19056636 DOI: 10.3945/jn.108.091967  1
2008 Zempleni J, Hassan YI, Wijeratne SS. Biotin and biotinidase deficiency. Expert Review of Endocrinology & Metabolism. 3: 715-724. PMID 19727438 DOI: 10.1586/17446651.3.6.715  1
2008 Chew YC, West JT, Kratzer SJ, Ilvarsonn AM, Eissenberg JC, Dave BJ, Klinkebiel D, Christman JK, Zempleni J. Biotinylation of histones represses transposable elements in human and mouse cells and cell lines and in Drosophila melanogaster. The Journal of Nutrition. 138: 2316-22. PMID 19022951 DOI: 10.3945/jn.108.098673  0.76
2008 Hassan YI, Zempleni J. A novel, enigmatic histone modification: biotinylation of histones by holocarboxylase synthetase. Nutrition Reviews. 66: 721-5. PMID 19019041 DOI: 10.1111/j.1753-4887.2008.00127.x  1
2008 Zempleni J, Chew YC, Hassan YI, Wijeratne SS. Epigenetic regulation of chromatin structure and gene function by biotin: are biotin requirements being met? Nutrition Reviews. 66: S46-8. PMID 18673490 DOI: 10.1111/j.1753-4887.2008.00073.x  1
2008 Kobza KA, Chaiseeda K, Sarath G, Takacs JM, Zempleni J. Biotinyl-methyl 4-(amidomethyl)benzoate is a competitive inhibitor of human biotinidase. The Journal of Nutritional Biochemistry. 19: 826-32. PMID 18479898 DOI: 10.1016/j.jnutbio.2007.11.002  0.76
2008 Kobza K, Sarath G, Zempleni J. Prokaryotic BirA ligase biotinylates K4, K9, K18 and K23 in histone H3. Bmb Reports. 41: 310-5. PMID 18452652  0.76
2008 Camporeale G, Chew YC, Kueh A, Sarath G, Zempleni J. Use of synthetic peptides for identifying biotinylation sites in human histones. Methods in Molecular Biology (Clifton, N.J.). 418: 139-48. PMID 18287656  0.76
2008 Gralla M, Camporeale G, Zempleni J. Holocarboxylase synthetase regulates expression of biotin transporters by chromatin remodeling events at the SMVT locus. The Journal of Nutritional Biochemistry. 19: 400-8. PMID 17904341 DOI: 10.1016/j.jnutbio.2007.06.002  1
2007 Smith EM, Hoi JT, Eissenberg JC, Shoemaker JD, Neckameyer WS, Ilvarsonn AM, Harshman LG, Schlegel VL, Zempleni J. Feeding Drosophila a biotin-deficient diet for multiple generations increases stress resistance and lifespan and alters gene expression and histone biotinylation patterns. The Journal of Nutrition. 137: 2006-12. PMID 17709434  0.76
2007 Camporeale G, Oommen AM, Griffin JB, Sarath G, Zempleni J. K12-biotinylated histone H4 marks heterochromatin in human lymphoblastoma cells. The Journal of Nutritional Biochemistry. 18: 760-8. PMID 17434721 DOI: 10.1016/j.jnutbio.2006.12.014  0.76
2007 Camporeale G, Zempleni J, Eissenberg JC. Susceptibility to heat stress and aberrant gene expression patterns in holocarboxylase synthetase-deficient Drosophila melanogaster are caused by decreased biotinylation of histones, not of carboxylases. The Journal of Nutrition. 137: 885-9. PMID 17374649  0.76
2007 Chew YC, Sarath G, Zempleni J. An avidin-based assay for histone debiotinylase activity in human cell nuclei. The Journal of Nutritional Biochemistry. 18: 475-81. PMID 17156993 DOI: 10.1016/j.jnutbio.2006.09.002  0.76
2006 Camporeale G, Giordano E, Rendina R, Zempleni J, Eissenberg JC. Drosophila melanogaster holocarboxylase synthetase is a chromosomal protein required for normal histone biotinylation, gene transcription patterns, lifespan, and heat tolerance. The Journal of Nutrition. 136: 2735-42. PMID 17056793  0.76
2006 Hassan YI, Zempleni J. Epigenetic regulation of chromatin structure and gene function by biotin. The Journal of Nutrition. 136: 1763-5. PMID 16772434  1
2006 Manthey KC, Rodriguez-Melendez R, Hoi JT, Zempleni J. Riboflavin deficiency causes protein and DNA damage in HepG2 cells, triggering arrest in G1 phase of the cell cycle. The Journal of Nutritional Biochemistry. 17: 250-6. PMID 16109485 DOI: 10.1016/j.jnutbio.2005.05.004  0.48
2006 Chew YC, Camporeale G, Kothapalli N, Sarath G, Zempleni J. Lysine residues in N-terminal and C-terminal regions of human histone H2A are targets for biotinylation by biotinidase. The Journal of Nutritional Biochemistry. 17: 225-33. PMID 16109483 DOI: 10.1016/j.jnutbio.2005.05.003  0.76
2006 Griffin JB, Rodriguez-Melendez R, Dode L, Wuytack F, Zempleni J. Biotin supplementation decreases the expression of the SERCA3 gene (ATP2A3) in Jurkat cells, thus, triggering unfolded protein response. The Journal of Nutritional Biochemistry. 17: 272-81. PMID 16109482 DOI: 10.1016/j.jnutbio.2005.05.005  0.76
2006 Rodriguez-Melendez R, Griffin JB, Zempleni J. The expression of genes encoding ribosomal subunits and eukaryotic translation initiation factor 5A depends on biotin and bisnorbiotin in HepG2 cells. The Journal of Nutritional Biochemistry. 17: 23-30. PMID 16081274 DOI: 10.1016/j.jnutbio.2005.04.001  0.76
2005 Kothapalli N, Sarath G, Zempleni J. Biotinylation of K12 in histone H4 decreases in response to DNA double-strand breaks in human JAr choriocarcinoma cells. The Journal of Nutrition. 135: 2337-42. PMID 16177192  0.76
2005 Kobza K, Camporeale G, Rueckert B, Kueh A, Griffin JB, Sarath G, Zempleni J. K4, K9 and K18 in human histone H3 are targets for biotinylation by biotinidase. The Febs Journal. 272: 4249-59. PMID 16098205 DOI: 10.1111/j.1742-4658.2005.04839.x  0.76
2005 Werner R, Manthey KC, Griffin JB, Zempleni J. HepG2 cells develop signs of riboflavin deficiency within 4 days of culture in riboflavin-deficient medium. The Journal of Nutritional Biochemistry. 16: 617-24. PMID 16081269 DOI: 10.1016/j.jnutbio.2005.03.006  0.76
2005 Kothapalli N, Camporeale G, Kueh A, Chew YC, Oommen AM, Griffin JB, Zempleni J. Biological functions of biotinylated histones. The Journal of Nutritional Biochemistry. 16: 446-8. PMID 15992689 DOI: 10.1016/j.jnutbio.2005.03.025  0.76
2005 Rodriguez-Melendez R, Griffin JB, Sarath G, Zempleni J. High-throughput immunoblotting identifies biotin-dependent signaling proteins in HepG2 hepatocarcinoma cells. The Journal of Nutrition. 135: 1659-66. PMID 15987846  0.76
2005 Manthey KC, Chew YC, Zempleni J. Riboflavin deficiency impairs oxidative folding and secretion of apolipoprotein B-100 in HepG2 cells, triggering stress response systems. The Journal of Nutrition. 135: 978-82. PMID 15867268  0.76
2005 Griffin JB, Zempleni J. Biotin deficiency stimulates survival pathways in human lymphoma cells exposed to antineoplastic drugs. The Journal of Nutritional Biochemistry. 16: 96-103. PMID 15681168 DOI: 10.1016/j.jnutbio.2004.10.004  0.76
2005 Oommen AM, Griffin JB, Sarath G, Zempleni J. Roles for nutrients in epigenetic events. The Journal of Nutritional Biochemistry. 16: 74-7. PMID 15681164 DOI: 10.1016/j.jnutbio.2004.08.004  0.76
2004 Landenberger A, Kabil H, Harshman LG, Zempleni J. Biotin deficiency decreases life span and fertility but increases stress resistance in Drosophila melanogaster. The Journal of Nutritional Biochemistry. 15: 591-600. PMID 15542350 DOI: 10.1016/j.jnutbio.2004.04.006  0.76
2004 Rodriguez-Melendez R, Griffin JB, Zempleni J. Biotin supplementation increases expression of the cytochrome P450 1B1 gene in Jurkat cells, increasing the occurrence of single-stranded DNA breaks. The Journal of Nutrition. 134: 2222-8. PMID 15333708  0.76
2004 Rodriguez-Melendez R, Schwab LD, Zempleni J. Jurkat cells respond to biotin deficiency with increased nuclear translocation of NF-kappaB, mediating cell survival. International Journal For Vitamin and Nutrition Research. Internationale Zeitschrift FüR Vitamin- Und ErnäHrungsforschung. Journal International De Vitaminologie Et De Nutrition. 74: 209-16. PMID 15296080 DOI: 10.1024/0300-9831.74.3.209  0.4
2004 Wiedmann S, Rodriguez-Melendez R, Ortega-Cuellar D, Zempleni J. Clusters of biotin-responsive genes in human peripheral blood mononuclear cells. The Journal of Nutritional Biochemistry. 15: 433-9. PMID 15219929 DOI: 10.1016/j.jnutbio.2004.02.005  0.4
2004 Camporeale G, Shubert EE, Sarath G, Cerny R, Zempleni J. K8 and K12 are biotinylated in human histone H4. European Journal of Biochemistry / Febs. 271: 2257-63. PMID 15153116 DOI: 10.1111/j.1432-1033.2004.04167.x  0.76
2004 Crisp SE, Griffin JB, White BR, Toombs CF, Camporeale G, Said HM, Zempleni J. Biotin supply affects rates of cell proliferation, biotinylation of carboxylases and histones, and expression of the gene encoding the sodium-dependent multivitamin transporter in JAr choriocarcinoma cells. European Journal of Nutrition. 43: 23-31. PMID 14991266 DOI: 10.1007/s00394-004-0435-9  0.76
2003 Rodriguez-Melendez R, Zempleni J. Regulation of gene expression by biotin (review). The Journal of Nutritional Biochemistry. 14: 680-90. PMID 14690760  0.4
2003 Griffin JB, Rodriguez-Melendez R, Zempleni J. The nuclear abundance of transcription factors Sp1 and Sp3 depends on biotin in Jurkat cells. The Journal of Nutrition. 133: 3409-15. PMID 14608051  0.76
2003 Daberkow RL, White BR, Cederberg RA, Griffin JB, Zempleni J. Monocarboxylate transporter 1 mediates biotin uptake in human peripheral blood mononuclear cells. The Journal of Nutrition. 133: 2703-6. PMID 12949353  0.76
2003 Rodriguez-Melendez R, Lewis B, McMahon RJ, Zempleni J. Diaminobiotin and desthiobiotin have biotin-like activities in Jurkat cells. The Journal of Nutrition. 133: 1259-64. PMID 12730407  0.76
2003 Camporeale G, Zempleni J. Oxidative folding of interleukin-2 is impaired in flavin-deficient jurkat cells, causing intracellular accumulation of interleukin-2 and increased expression of stress response genes. The Journal of Nutrition. 133: 668-72. PMID 12612135  1
2003 Rodriguez-Melendez R, Camporeale G, Griffin JB, Zempleni J. Interleukin-2 receptor-gamma -dependent endocytosis depends on biotin in Jurkat cells. American Journal of Physiology. Cell Physiology. 284: C415-21. PMID 12388078 DOI: 10.1152/ajpcell.00365.2002  0.76
2002 Griffin JB, Stanley JS, Zempleni J. Synthesis of a rabbit polyclonal antibody to the human sodium-dependent multivitamin transporter. International Journal For Vitamin and Nutrition Research. Internationale Zeitschrift FüR Vitamin- Und ErnäHrungsforschung. Journal International De Vitaminologie Et De Nutrition. 72: 195-8. PMID 12214555 DOI: 10.1024/0300-9831.72.4.195  0.76
2002 Peters DM, Griffin JB, Stanley JS, Beck MM, Zempleni J. Exposure to UV light causes increased biotinylation of histones in Jurkat cells. American Journal of Physiology. Cell Physiology. 283: C878-84. PMID 12176744 DOI: 10.1152/ajpcell.00107.2002  0.76
2002 Stanley JS, Mock DM, Griffin JB, Zempleni J. Biotin uptake into human peripheral blood mononuclear cells increases early in the cell cycle, increasing carboxylase activities. The Journal of Nutrition. 132: 1854-9. PMID 12097659  0.76
2002 Ballard TD, Wolff J, Griffin JB, Stanley JS, van Calcar S, Zempleni J. Biotinidase catalyzes debiotinylation of histones. European Journal of Nutrition. 41: 78-84. PMID 12083317 DOI: 10.1007/s003940200011  0.76
2002 Mardach R, Zempleni J, Wolf B, Cannon MJ, Jennings ML, Cress S, Boylan J, Roth S, Cederbaum S, Mock DM. Biotin dependency due to a defect in biotin transport. The Journal of Clinical Investigation. 109: 1617-23. PMID 12070309 DOI: 10.1172/JCI13138  0.76
2002 Manthey KC, Griffin JB, Zempleni J. Biotin supply affects expression of biotin transporters, biotinylation of carboxylases and metabolism of interleukin-2 in Jurkat cells. The Journal of Nutrition. 132: 887-92. PMID 11983808  0.76
2001 Zempleni J, Steven Stanley J, Mock DM. Proliferation of peripheral blood mononuclear cells causes increased expression of the sodium-dependent multivitamin transporter gene and increased uptake of pantothenic acidopen star The Journal of Nutritional Biochemistry. 12: 465-473. PMID 11834205 DOI: 10.1016/S0955-2863(01)00162-0  0.76
2001 Steven Stanley J, Griffin JB, Zempleni J. Biotinylation of histones in human cells: Effects of cell proliferation European Journal of Biochemistry. 268: 5424-5429. PMID 11606205 DOI: 10.1046/j.0014-2956.2001.02481.x  0.76
2001 Zempleni J, Helm RM, Mock DM. In vivo biotin supplementation at a pharmacologic dose decreases proliferation rates of human peripheral blood mononuclear cells and cytokine release Journal of Nutrition. 131: 1479-1484. PMID 11340103 DOI: 10.1093/jn/131.5.1479  0.76
2000 Zempleni J, Mock DM. Utilization of biotin in proliferating human lymphocytes Journal of Nutrition. 130: 335S-337S. PMID 10721900 DOI: 10.1093/jn/130.2.335S  0.76
1999 Zempleni J, Mock DM. Biotin biochemistry and human requirements. The Journal of Nutritional Biochemistry. 10: 128-38. PMID 15539280 DOI: 10.1016/S0955-2863(98)00095-3  0.76
1999 Zempleni J, Mock DM. The efflux of biotin from human peripheral blood mononuclear cells. The Journal of Nutritional Biochemistry. 10: 105-9. PMID 15539277 DOI: 10.1016/S0955-2863(98)00089-8  0.76
1999 Zempleni J, Mock DM. Chemical synthesis of biotinylated histones and analysis by sodium dodecyl sulfate-polyacrylamide gel electrophoresis/streptavidin-peroxidase Archives of Biochemistry and Biophysics. 371: 83-88. PMID 10525292 DOI: 10.1006/abbi.1999.1431  0.76
1999 Zempleni J, Mock DM. Mitogen-induced proliferation increases biotin uptake into human peripheral blood mononuclear cells American Journal of Physiology - Cell Physiology. 276: C1079-C1084. PMID 10329955 DOI: 10.1152/ajpcell.1999.276.5.C1079  0.76
1999 Zempleni J, Mock DM. Bioavailability of biotin given orally to humans in pharmacologic doses American Journal of Clinical Nutrition. 69: 504-508. PMID 10075337 DOI: 10.1093/ajcn/69.3.504  0.76
1999 Zempleni J, Mock DM. Advanced analysis of biotin metabolites in body fluids allows a more accurate measurement of biotin bioavailability and metabolism in humans Journal of Nutrition. 129: 494S-497S. PMID 10064316 DOI: 10.1093/jn/129.2.494S  0.76
1999 Zempleni J, Mock DM. Human peripheral blood mononuclear cells: Inhibition of biotin transport by reversible competition with pantothenic acid is quantitatively minor Journal of Nutritional Biochemistry. 10: 427-432. DOI: 10.1016/S0955-2863(99)00024-8  0.76
1998 Zempleni J, Mock DM. Uptake and metabolism of biotin by human peripheral blood mononuclear cells American Journal of Physiology - Cell Physiology. 275. PMID 9688592 DOI: 10.1152/ajpcell.1998.275.2.C382  0.76
1997 Zempleni J, Trusty TA, Mock DM. Lipoic acid reduces the activities of biotin-dependent carboxylases in rat liver Journal of Nutrition. 127: 1776-1781. PMID 9278559 DOI: 10.1093/jn/127.9.1776  0.76
1997 Zempleni J, McCormick DB, Mock DM. Identification of biotin sulfone, bisnorbiotin methyl ketone, and tetranorbiotin-/-sulfoxide in human urine American Journal of Clinical Nutrition. 65: 508-511. PMID 9022537 DOI: 10.1093/ajcn/65.2.508  0.76
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