Brad C. Bennett, Ph.D. - Publications

Affiliations: 
2005 The University of Tennessee, Knoxville, TN, United States 
Area:
Biochemistry, Pharmaceutical Chemistry

14 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Wan Q, Bennett BC, Wymore T, Li Z, Wilson MA, Brooks CL, Langan P, Kovalevsky A, Dealwis CG. Capturing the Catalytic Proton of Dihydrofolate Reductase: Implications for General Acid-Base Catalysis. Acs Catalysis. 11: 5873-5884. PMID 34055457 DOI: 10.1021/acscatal.1c00417  0.672
2014 Wan Q, Bennett BC, Wilson MA, Kovalevsky A, Langan P, Howell EE, Dealwis C. Toward resolving the catalytic mechanism of dihydrofolate reductase using neutron and ultrahigh-resolution X-ray crystallography. Proceedings of the National Academy of Sciences of the United States of America. 111: 18225-30. PMID 25453083 DOI: 10.1073/Pnas.1415856111  0.703
2014 Purdy MD, Bennett BC, McIntire WE, Khan AK, Kasson PM, Yeager M. Function and dynamics of macromolecular complexes explored by integrative structural and computational biology. Current Opinion in Structural Biology. 27: 138-48. PMID 25238653 DOI: 10.1016/J.Sbi.2014.08.006  0.378
2014 Wan Q, Kovalevsky AY, Wilson MA, Bennett BC, Langan P, Dealwis C. Preliminary joint X-ray and neutron protein crystallographic studies of ecDHFR complexed with folate and NADP+. Acta Crystallographica. Section F, Structural Biology Communications. 70: 814-8. PMID 24915100 DOI: 10.1107/S2053230X1400942X  0.68
2013 Lee SC, Bennett BC, Hong WX, Fu Y, Baker KA, Marcoux J, Robinson CV, Ward AB, Halpert JR, Stevens RC, Stout CD, Yeager MJ, Zhang Q. Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins. Proceedings of the National Academy of Sciences of the United States of America. 110: E1203-11. PMID 23479627 DOI: 10.1073/Pnas.1221442110  0.391
2013 Bennett B, Purdy M, Baker K, McIntire W, Stevens R, Zhang Q, Yeager M. X-Ray Structure of the Cx26 Gap Junction Channel and Comparison with the Cryo-EM Structure of Cx43 Biophysical Journal. 104: 42a-43a. DOI: 10.1016/J.Bpj.2012.11.272  0.386
2011 Miyagi M, Wan Q, Ahmad MF, Gokulrangan G, Tomechko SE, Bennett B, Dealwis C. Histidine hydrogen-deuterium exchange mass spectrometry for probing the microenvironment of histidine residues in dihydrofolate reductase. Plos One. 6: e17055. PMID 21359214 DOI: 10.1371/Journal.Pone.0017055  0.633
2010 Bennett BC, Yeager M. The lighter side of a sweet reaction. Structure (London, England : 1993). 18: 657-9. PMID 20541500 DOI: 10.1016/J.Str.2010.05.006  0.44
2009 Bennett BC, Wan Q, Ahmad MF, Langan P, Dealwis CG. X-ray structure of the ternary MTX.NADPH complex of the anthrax dihydrofolate reductase: a pharmacophore for dual-site inhibitor design. Journal of Structural Biology. 166: 162-71. PMID 19374017 DOI: 10.1016/J.Jsb.2009.01.001  0.68
2008 Bennett BC, Gardberg AS, Blair MD, Dealwis CG. On the determinants of amide backbone exchange in proteins: a neutron crystallographic comparative study. Acta Crystallographica. Section D, Biological Crystallography. 764-83. PMID 18566512 DOI: 10.1107/S0907444908012845  0.691
2008 Langan P, Fisher Z, Kovalevsky A, Mustyakimov M, Sutcliffe Valone A, Unkefer C, Waltman MJ, Coates L, Adams PD, Afonine PV, Bennett B, Dealwis C, Schoenborn BP. Protein structures by spallation neutron crystallography. Journal of Synchrotron Radiation. 15: 215-8. PMID 18421142 DOI: 10.1107/S0909049508000824  0.659
2007 Bennett BC, Xu H, Simmerman RF, Lee RE, Dealwis CG. Crystal structure of the anthrax drug target, Bacillus anthracis dihydrofolate reductase. Journal of Medicinal Chemistry. 50: 4374-81. PMID 17696333 DOI: 10.1021/Jm070319V  0.656
2006 Bennett B, Langan P, Coates L, Mustyakimov M, Schoenborn B, Howell EE, Dealwis C. Neutron diffraction studies of Escherichia coli dihydrofolate reductase complexed with methotrexate. Proceedings of the National Academy of Sciences of the United States of America. 103: 18493-8. PMID 17130456 DOI: 10.1073/Pnas.0604977103  0.704
2005 Bennett BC, Meilleur F, Myles DA, Howell EE, Dealwis CG. Preliminary neutron diffraction studies of Escherichia coli dihydrofolate reductase bound to the anticancer drug methotrexate. Acta Crystallographica. Section D, Biological Crystallography. 61: 574-9. PMID 15858267 DOI: 10.1107/S0907444905004804  0.699
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