| Year |
Citation |
Score |
| 2024 |
Yi F, Cohen T, Zimmerman N, Dündar F, Zumbo P, Eltilib R, Brophy EJ, Arkin H, Feucht J, Gormally MV, Hackett CS, Kropp KN, Etxeberria I, Chandran SS, Park JH, et al. CAR-engineered lymphocyte persistence is governed by a FAS ligand/FAS auto-regulatory circuit. Biorxiv : the Preprint Server For Biology. PMID 38464085 DOI: 10.1101/2024.02.26.582108 |
0.404 |
|
| 2023 |
Klebanoff CA, Chandran SS, Baker BM, Quezada SA, Ribas A. T cell receptor therapeutics: immunological targeting of the intracellular cancer proteome. Nature Reviews. Drug Discovery. PMID 37891435 DOI: 10.1038/s41573-023-00809-z |
0.391 |
|
| 2020 |
Drakes DJ, Rafiq S, Purdon TJ, Lopez AV, Chandran SS, Klebanoff CA, Brentjens RJ. Optimization of T-cell receptor-modified T cells for cancer therapy. Cancer Immunology Research. PMID 32209638 DOI: 10.1158/2326-6066.CIR-19-0910 |
0.445 |
|
| 2020 |
Gejman RS, Jones HF, Klatt MG, Chang AY, Oh CY, Chandran SS, Korontsvit T, Zakahleva V, Dao T, Klebanoff CA, Scheinberg DA. Identification of the targets of T cell receptor therapeutic agents and cells by use of a high throughput genetic platform. Cancer Immunology Research. PMID 32184297 DOI: 10.1158/2326-6066.Cir-19-0745 |
0.319 |
|
| 2019 |
Chandran SS, Klebanoff CA. T cell receptor-based cancer immunotherapy: Emerging efficacy and pathways of resistance. Immunological Reviews. 290: 127-147. PMID 31355495 DOI: 10.1111/imr.12772 |
0.443 |
|
| 2019 |
Scott AC, Dündar F, Zumbo P, Chandran SS, Klebanoff CA, Shakiba M, Trivedi P, Menocal L, Appleby H, Camara SJ, Zamarin D, Walther T, Snyder AC, Femia MR, Comen EA, et al. TOX is a critical regulator of tumour-specific T cell differentiation. Nature. PMID 31207604 DOI: 10.1038/S41586-019-1324-Y |
0.57 |
|
| 2019 |
Chandran S, Ma J, Klatt MG, Dündar F, Zumbo P, Femia MR, Betel D, Scheinberg DA, Baker BM, Klebanoff CA. Abstract CN01-03: T cell receptor gene therapy for a public neoantigen derived from mutated PIK3CA, a dominant driver oncogene in breast and endometrial cancers Molecular Cancer Therapeutics. 18. DOI: 10.1158/1535-7163.Targ-19-Cn01-03 |
0.318 |
|
| 2017 |
Klebanoff CA, Crompton JG, Leonardi AJ, Yamamoto TN, Chandran SS, Eil RL, Sukumar M, Vodnala SK, Hu J, Ji Y, Clever D, Black MA, Gurusamy D, Kruhlak MJ, Jin P, et al. Inhibition of AKT signaling uncouples T cell differentiation from expansion for receptor-engineered adoptive immunotherapy. Jci Insight. 2. PMID 29212954 DOI: 10.1172/Jci.Insight.95103 |
0.537 |
|
| 2017 |
Chandran SS, Somerville RP, Yang JC, Sherry RM, Klebanoff CA, Goff SL, Wunderlich JR, Danforth DN, Zlott D, Paria BC, Sabesan AC, Srivastava AK, Xi L, Pham TH, Raffeld M, et al. Treatment of metastatic uveal melanoma with adoptive transfer of tumour-infiltrating lymphocytes: a single-centre, two-stage, single-arm, phase 2 study. The Lancet. Oncology. PMID 28395880 DOI: 10.1016/S1470-2045(17)30251-6 |
0.368 |
|
| 2015 |
Rothermel LD, Sabesan A, Stephens DJ, Chandran SS, Paria BC, Srivastava AK, Somerville RP, Wunderlich JR, Lee CR, Xi L, Pham T, Raffeld M, Jailwala P, Kasoji M, Kammula US. Identification of an immunogenic subset of metastatic uveal melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26712692 DOI: 10.1158/1078-0432.Ccr-15-2294 |
0.395 |
|
| 2015 |
Chandran SS, Paria BC, Srivastava AK, Rothermel LD, Stephens DJ, Kammula US. Tumor-specific effector CD8+ T cells that can establish immunological memory in humans after adoptive transfer are marked by expression of IL-7 receptor and c-MYC. Cancer Research. PMID 26100671 DOI: 10.1158/0008-5472.Can-15-0584 |
0.606 |
|
| 2015 |
Beane JD, Lee G, Zheng Z, Mendel M, Abate-Daga D, Bharathan M, Black M, Gandhi N, Yu Z, Chandran S, Giedlin M, Ando D, Miller J, Paschon D, Guschin D, et al. Clinical Scale Zinc Finger Nuclease-mediated Gene Editing of PD-1 in Tumor Infiltrating Lymphocytes for the Treatment of Metastatic Melanoma. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 25939491 DOI: 10.1038/Mt.2015.71 |
0.345 |
|
| 2015 |
Chandran SS, Paria BC, Srivastava AK, Rothermel LD, Stephens DJ, Dudley ME, Somerville R, Wunderlich JR, Sherry RM, Yang JC, Rosenberg SA, Kammula US. Persistence of CTL clones targeting melanocyte differentiation antigens was insufficient to mediate significant melanoma regression in humans. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 534-43. PMID 25424856 DOI: 10.1158/1078-0432.Ccr-14-2208 |
0.474 |
|
| 2015 |
Beane JD, Lee G, Zheng Z, Gandhi N, Abate-Daga D, Bharathan M, Black M, Mendel M, Yu Z, Kassim SH, Chandran S, Giedlin MA, Ando D, Rebar E, Reik A, et al. 77. Clinical Scale Zinc Finger Nuclease (ZFN)-Driven Gene-Editing of PD-1 in Tumor Infiltrating Lymphocytes (TIL) for the Potential Treatment of Metastatic Melanoma Molecular Therapy. 23: S33-S34. DOI: 10.1016/S1525-0016(16)33682-6 |
0.408 |
|
| 2012 |
Wang A, Chandran S, Shah SA, Chiu Y, Paria BC, Aghamolla T, Alvarez-Downing MM, Lee CC, Singh S, Li T, Dudley ME, Restifo NP, Rosenberg SA, Kammula US. The stoichiometric production of IL-2 and IFN-γ mRNA defines memory T cells that can self-renew after adoptive transfer in humans. Science Translational Medicine. 4: 149ra120. PMID 22932225 DOI: 10.1126/Scitranslmed.3004306 |
0.535 |
|
| 2009 |
Chandran SS, Verhoeven D, Teijaro JR, Fenton MJ, Farber DL. TLR2 engagement on dendritic cells promotes high frequency effector and memory CD4 T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 183: 7832-41. PMID 19933854 DOI: 10.4049/Jimmunol.0901683 |
0.627 |
|
| 2009 |
Teijaro JR, Njau MN, Verhoeven D, Chandran S, Nadler SG, Hasday J, Farber DL. Costimulation modulation uncouples protection from immunopathology in memory T cell responses to influenza virus. Journal of Immunology (Baltimore, Md. : 1950). 182: 6834-43. PMID 19454679 DOI: 10.4049/Jimmunol.0803860 |
0.61 |
|
| 2008 |
Tang AL, Teijaro JR, Njau MN, Chandran SS, Azimzadeh A, Nadler SG, Rothstein DM, Farber DL. CTLA4 expression is an indicator and regulator of steady-state CD4+ FoxP3+ T cell homeostasis. Journal of Immunology (Baltimore, Md. : 1950). 181: 1806-13. PMID 18641318 DOI: 10.4049/Jimmunol.181.3.1806 |
0.592 |
|
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