Roberto J. Botelho, Ph.D. - Publications

2004 University of Toronto, Toronto, ON, Canada 
Cell Biology

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Ho CY, Choy CH, Botelho RJ. Radiolabeling and Quantification of Cellular Levels of Phosphoinositides by High Performance Liquid Chromatography-coupled Flow Scintillation. Journal of Visualized Experiments : Jove. PMID 26780479 DOI: 10.3791/53529  0.44
2015 Saric A, Hipolito VE, Kay JG, Canton J, Antonescu CN, Botelho RJ. mTOR controls lysosome tubulation and antigen presentation in macrophages and dendritic cells. Molecular Biology of the Cell. PMID 26582390 DOI: 10.1091/mbc.E15-05-0272  0.44
2015 Dayam RM, Saric A, Shilliday RE, Botelho RJ. The Phosphoinositide-Gated Lysosomal Ca(2+) Channel, TRPML1, Is Required for Phagosome Maturation. Traffic (Copenhagen, Denmark). 16: 1010-26. PMID 26010303 DOI: 10.1111/tra.12303  0.44
2015 Ho CY, Choy CH, Wattson CA, Johnson DE, Botelho RJ. The Fab1/PIKfyve phosphoinositide phosphate kinase is not necessary to maintain the pH of lysosomes and of the yeast vacuole. The Journal of Biological Chemistry. 290: 9919-28. PMID 25713145 DOI: 10.1074/jbc.M114.613984  0.44
2012 Mrakovic A, Kay JG, Furuya W, Brumell JH, Botelho RJ. Rab7 and Arl8 GTPases are necessary for lysosome tubulation in macrophages. Traffic (Copenhagen, Denmark). 13: 1667-79. PMID 22909026 DOI: 10.1111/tra.12003  0.44
2011 Botelho RJ, Grinstein S. Phagocytosis. Current Biology : Cb. 21: R533-8. PMID 21783028 DOI: 10.1016/j.cub.2011.05.053  0.68
2009 Fairn GD, Ogata K, Botelho RJ, Stahl PD, Anderson RA, De Camilli P, Meyer T, Wodak S, Grinstein S. An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis. The Journal of Cell Biology. 187: 701-14. PMID 19951917 DOI: 10.1083/jcb.200909025  0.44
2009 Botelho RJ, Harrison RE, Stone JC, Hancock JF, Philips MR, Jongstra-Bilen J, Mason D, Plumb J, Gold MR, Grinstein S. Localized diacylglycerol-dependent stimulation of Ras and Rap1 during phagocytosis. The Journal of Biological Chemistry. 284: 28522-32. PMID 19700408 DOI: 10.1074/jbc.M109.009514  0.44
2008 Botelho RJ, Efe JA, Teis D, Emr SD. Assembly of a Fab1 phosphoinositide kinase signaling complex requires the Fig4 phosphoinositide phosphatase. Molecular Biology of the Cell. 19: 4273-86. PMID 18653468 DOI: 10.1091/mbc.E08-04-0405  0.44
2007 Efe JA, Botelho RJ, Emr SD. Atg18 regulates organelle morphology and Fab1 kinase activity independent of its membrane recruitment by phosphatidylinositol 3,5-bisphosphate. Molecular Biology of the Cell. 18: 4232-44. PMID 17699591 DOI: 10.1091/mbc.E07-04-0301  0.44
2005 Efe JA, Botelho RJ, Emr SD. The Fab1 phosphatidylinositol kinase pathway in the regulation of vacuole morphology. Current Opinion in Cell Biology. 17: 402-8. PMID 15975782 DOI: 10.1016/  0.44
2005 Tse SM, Mason D, Botelho RJ, Chiu B, Reyland M, Hanada K, Inman RD, Grinstein S. Accumulation of diacylglycerol in the Chlamydia inclusion vacuole: possible role in the inhibition of host cell apoptosis. The Journal of Biological Chemistry. 280: 25210-5. PMID 15863503 DOI: 10.1074/jbc.M501980200  0.68
2005 Scott CC, Dobson W, Botelho RJ, Coady-Osberg N, Chavrier P, Knecht DA, Heath C, Stahl P, Grinstein S. Phosphatidylinositol-4,5-bisphosphate hydrolysis directs actin remodeling during phagocytosis. The Journal of Cell Biology. 169: 139-49. PMID 15809313 DOI: 10.1083/jcb.200412162  0.44
2004 Botelho RJ, Scott CC, Grinstein S. Phosphoinositide involvement in phagocytosis and phagosome maturation. Current Topics in Microbiology and Immunology. 282: 1-30. PMID 14594212  0.44
2003 Scott CC, Botelho RJ, Grinstein S. Phagosome maturation: a few bugs in the system. The Journal of Membrane Biology. 193: 137-52. PMID 12962275 DOI: 10.1007/s00232-002-2008-2  0.44
2003 Gu H, Botelho RJ, Yu M, Grinstein S, Neel BG. Critical role for scaffolding adapter Gab2 in FcγR-mediated phagocytosis Journal of Cell Biology. 161: 1151-1161. PMID 12821647 DOI: 10.1083/jcb.200212158  0.44
2003 Dombrosky-Ferlan P, Grishin A, Botelho RJ, Sampson M, Wang L, Rudert WA, Grinstein S, Corey SJ. Felic (CIP4b), a novel binding partner with the Src kinase Lyn and Cdc42, localizes to the phagocytic cup. Blood. 101: 2804-9. PMID 12456510 DOI: 10.1182/blood-2002-03-0851  0.68
2002 Botelho RJ, Tapper H, Furuya W, Mojdami D, Grinstein S. Fc gamma R-mediated phagocytosis stimulates localized pinocytosis in human neutrophils. Journal of Immunology (Baltimore, Md. : 1950). 169: 4423-9. PMID 12370376 DOI: 10.4049/jimmunol.169.8.4423  0.68
2002 Vieira OV, Botelho RJ, Grinstein S. Phagosome maturation: aging gracefully. The Biochemical Journal. 366: 689-704. PMID 12061891 DOI: 10.1042/BJ20020691  0.68
2001 Vieira OV, Botelho RJ, Rameh L, Brachmann SM, Matsuo T, Davidson HW, Schreiber A, Backer JM, Cantley LC, Grinstein S. Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation. The Journal of Cell Biology. 155: 19-25. PMID 11581283 DOI: 10.1083/jcb.200107069  0.68
2001 Hackam DJ, Botelho RJ, Sjolin C, Rotstein OD, Robinson JM, Schreiber AD, Grinstein S. Indirect role for COPI in the completion of FCgamma receptor-mediated phagocytosis. The Journal of Biological Chemistry. 276: 18200-8. PMID 11279223 DOI: 10.1074/jbc.M102009200  0.44
2000 Botelho RJ, Teruel M, Dierckman R, Anderson R, Wells A, York JD, Meyer T, Grinstein S. Localized biphasic changes in phosphatidylinositol-4,5-bisphosphate at sites of phagocytosis. The Journal of Cell Biology. 151: 1353-68. PMID 11134066 DOI: 10.1083/jcb.151.7.1353  0.68
2000 Botelho RJ, Hackam DJ, Schreiber AD, Grinstein S. Role of COPI in phagosome maturation. The Journal of Biological Chemistry. 275: 15717-27. PMID 10748188 DOI: 10.1074/jbc.M910068199  0.44
1999 Downey GP, Botelho RJ, Butler JR, Moltyaner Y, Chien P, Schreiber AD, Grinstein S. Phagosomal maturation, acidification, and inhibition of bacterial growth in nonphagocytic cells transfected with FcgammaRIIA receptors. The Journal of Biological Chemistry. 274: 28436-44. PMID 10497205 DOI: 10.1074/jbc.274.40.28436  0.44
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