Chih-Chiun Chen, Ph.D. - Publications

2001 University of Illinois at Chicago, Health Sciences Center, Chicago, IL 60612, United States 
Cell Biology, Molecular Biology, Oncology

22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Chen CC, Kim KH, Lau LF. The matricellular protein CCN1 suppresses hepatocarcinogenesis by inhibiting compensatory proliferation. Oncogene. PMID 26028023 DOI: 10.1038/Onc.2015.190  0.626
2015 Kim KH, Chen CC, Alpini G, Lau LF. CCN1 induces hepatic ductular reaction through integrin αvβ₅-mediated activation of NF-κB. The Journal of Clinical Investigation. 125: 1886-900. PMID 25822023 DOI: 10.1172/Jci79327  0.57
2013 Kim KH, Chen CC, Monzon RI, Lau LF. Matricellular protein CCN1 promotes regression of liver fibrosis through induction of cellular senescence in hepatic myofibroblasts. Molecular and Cellular Biology. 33: 2078-90. PMID 23508104 DOI: 10.1128/Mcb.00049-13  0.556
2012 Juric V, Chen CC, Lau LF. TNFα-induced apoptosis enabled by CCN1/CYR61: pathways of reactive oxygen species generation and cytochrome c release. Plos One. 7: e31303. PMID 22363611 DOI: 10.1371/Journal.Pone.0031303  0.629
2011 Chen CC, Juric V, Lau LF. The extracellular matrix protein CCN1 dictates TNFα and FasL cytotoxicity in vivo. Advances in Experimental Medicine and Biology. 691: 595-603. PMID 21153366 DOI: 10.1007/978-1-4419-6612-4_63  0.661
2010 Bai T, Chen CC, Lau LF. Matricellular protein CCN1 activates a proinflammatory genetic program in murine macrophages. Journal of Immunology (Baltimore, Md. : 1950). 184: 3223-32. PMID 20164416 DOI: 10.4049/Jimmunol.0902792  0.716
2010 Chen CC, Lau LF. Deadly liaisons: fatal attraction between CCN matricellular proteins and the tumor necrosis factor family of cytokines. Journal of Cell Communication and Signaling. 4: 63-9. PMID 19898959 DOI: 10.1007/S12079-009-0080-4  0.7
2009 Franzen CA, Chen CC, Todorović V, Juric V, Monzon RI, Lau LF. Matrix protein CCN1 is critical for prostate carcinoma cell proliferation and TRAIL-induced apoptosis. Molecular Cancer Research : McR. 7: 1045-55. PMID 19584265 DOI: 10.1158/1541-7786.Mcr-09-0017  0.788
2009 Juric V, Chen CC, Lau LF. Fas-mediated apoptosis is regulated by the extracellular matrix protein CCN1 (CYR61) in vitro and in vivo. Molecular and Cellular Biology. 29: 3266-79. PMID 19364818 DOI: 10.1128/Mcb.00064-09  0.675
2009 Chen CC, Lau LF. Functions and mechanisms of action of CCN matricellular proteins. The International Journal of Biochemistry & Cell Biology. 41: 771-83. PMID 18775791 DOI: 10.1016/J.Biocel.2008.07.025  0.683
2007 Chen CC, Young JL, Monzon RI, Chen N, Todorović V, Lau LF. Cytotoxicity of TNFalpha is regulated by integrin-mediated matrix signaling. The Embo Journal. 26: 1257-67. PMID 17318182 DOI: 10.1038/Sj.Emboj.7601596  0.806
2005 Todorovic V, Chen CC, Hay N, Lau LF. The matrix protein CCN1 (CYR61) induces apoptosis in fibroblasts. The Journal of Cell Biology. 171: 559-68. PMID 16275757 DOI: 10.1083/Jcb.200504015  0.696
2005 Lin CG, Chen CC, Leu SJ, Grzeszkiewicz TM, Lau LF. Integrin-dependent functions of the angiogenic inducer NOV (CCN3): implication in wound healing. The Journal of Biological Chemistry. 280: 8229-37. PMID 15611078 DOI: 10.1074/Jbc.M404903200  0.738
2004 Leu SJ, Chen N, Chen CC, Todorovic V, Bai T, Juric V, Liu Y, Yan G, Lam SC, Lau LF. Targeted mutagenesis of the angiogenic protein CCN1 (CYR61). Selective inactivation of integrin alpha6beta1-heparan sulfate proteoglycan coreceptor-mediated cellular functions. The Journal of Biological Chemistry. 279: 44177-87. PMID 15322081 DOI: 10.1074/Jbc.M407850200  0.72
2003 Leu SJ, Liu Y, Chen N, Chen CC, Lam SC, Lau LF. Identification of a novel integrin alpha 6 beta 1 binding site in the angiogenic inducer CCN1 (CYR61). The Journal of Biological Chemistry. 278: 33801-8. PMID 12826661 DOI: 10.1074/Jbc.M305862200  0.759
2002 Mo FE, Muntean AG, Chen CC, Stolz DB, Watkins SC, Lau LF. CYR61 (CCN1) is essential for placental development and vascular integrity. Molecular and Cellular Biology. 22: 8709-20. PMID 12446788 DOI: 10.1128/Mcb.22.24.8709-8720.2002  0.793
2001 Chen CC, Mo FE, Lau LF. The angiogenic factor Cyr61 activates a genetic program for wound healing in human skin fibroblasts. The Journal of Biological Chemistry. 276: 47329-37. PMID 11584015 DOI: 10.1074/Jbc.M107666200  0.822
2001 Chen CC, Chen N, Lau LF. The angiogenic factors Cyr61 and connective tissue growth factor induce adhesive signaling in primary human skin fibroblasts. The Journal of Biological Chemistry. 276: 10443-52. PMID 11120741 DOI: 10.1074/Jbc.M008087200  0.829
2000 Chen N, Chen CC, Lau LF. Adhesion of human skin fibroblasts to Cyr61 is mediated through integrin alpha 6beta 1 and cell surface heparan sulfate proteoglycans. The Journal of Biological Chemistry. 275: 24953-61. PMID 10821835 DOI: 10.1074/Jbc.M003040200  0.827
1999 Jedsadayanmata A, Chen CC, Kireeva ML, Lau LF, Lam SC. Activation-dependent adhesion of human platelets to Cyr61 and Fisp12/mouse connective tissue growth factor is mediated through integrin alpha(IIb)beta(3). The Journal of Biological Chemistry. 274: 24321-7. PMID 10446209 DOI: 10.1074/Jbc.274.34.24321  0.739
1999 Babic AM, Chen CC, Lau LF. Fisp12/mouse connective tissue growth factor mediates endothelial cell adhesion and migration through integrin alphavbeta3, promotes endothelial cell survival, and induces angiogenesis in vivo. Molecular and Cellular Biology. 19: 2958-66. PMID 10082563 DOI: 10.1128/Mcb.19.4.2958  0.713
1997 Kireeva ML, Latinkić BV, Kolesnikova TV, Chen CC, Yang GP, Abler AS, Lau LF. Cyr61 and Fisp12 are both ECM-associated signaling molecules: activities, metabolism, and localization during development. Experimental Cell Research. 233: 63-77. PMID 9184077 DOI: 10.1006/Excr.1997.3548  0.697
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