Steven G. Van Lanen, Ph.D. - Publications

Affiliations: 
2003 Portland State University, Portland, OR, United States 
Area:
Biochemistry

32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Huber TD, Wang F, Singh S, Johnson BR, Zhang J, Sunkara M, Van Lanen SG, Morris AJ, Phillips GN, Thorson JS. Functional AdoMet isosteres resistant to classical AdoMet degradation pathways. Acs Chemical Biology. PMID 27351335 DOI: 10.1021/acschembio.6b00348  0.52
2016 Liu X, Jin Y, Cai W, Green KD, Goswami A, Garneau-Tsodikova S, Nonaka K, Baba S, Funabashi M, Yang Z, Van Lanen SG. A biocatalytic approach to capuramycin analogues by exploiting a substrate permissive N-transacylase CapW. Organic & Biomolecular Chemistry. PMID 27050157 DOI: 10.1039/c6ob00381h  0.52
2016 Liu X, Jin Y, Cui Z, Nonaka K, Baba S, Funabashi M, Yang Z, Van Lanen SG. The Role of a Nonribosomal Peptide Synthetase in L-Lysine Lactamization During Capuramycin Biosynthesis. Chembiochem : a European Journal of Chemical Biology. PMID 26840634 DOI: 10.1002/cbic.201500701  0.52
2015 Kulkarni A, Zeng Y, Zhou W, Van Lanen S, Zhang W, Chen S. A branch point of Streptomyces sulfur amino acid metabolism controls the production of albomycin. Applied and Environmental Microbiology. PMID 26519385 DOI: 10.1128/AEM.02517-15  0.52
2015 Wang X, Reynolds AR, Elshahawi SI, Shaaban KA, Ponomareva LV, Saunders MA, Elgumati IS, Zhang Y, Copley GC, Hower JC, Sunkara M, Morris AJ, Kharel MK, Van Lanen SG, Prendergast MA, et al. Terfestatins B and C, New p-Terphenyl Glycosides Produced by Streptomyces sp. RM-5-8. Organic Letters. 17: 2796-9. PMID 25961722 DOI: 10.1021/acs.orglett.5b01203  0.52
2015 Cai W, Goswami A, Yang Z, Liu X, Green KD, Barnard-Britson S, Baba S, Funabashi M, Nonaka K, Sunkara M, Morris AJ, Spork AP, Ducho C, Garneau-Tsodikova S, Thorson JS, ... Van Lanen SG, et al. The Biosynthesis of Capuramycin-type Antibiotics: IDENTIFICATION OF THE A-102395 BIOSYNTHETIC GENE CLUSTER, MECHANISM OF SELF-RESISTANCE, AND FORMATION OF URIDINE-5'-CARBOXAMIDE. The Journal of Biological Chemistry. 290: 13710-24. PMID 25855790 DOI: 10.1074/jbc.M115.646414  0.52
2014 Singh S, Zhang J, Huber TD, Sunkara M, Hurley K, Goff RD, Wang G, Zhang W, Liu C, Rohr J, Van Lanen SG, Morris AJ, Thorson JS. Facile chemoenzymatic strategies for the synthesis and utilization of S-adenosyl-(L)-methionine analogues. Angewandte Chemie (International Ed. in English). 53: 3965-9. PMID 24616228 DOI: 10.1002/anie.201308272  0.52
2013 Funabashi M, Baba S, Takatsu T, Kizuka M, Ohata Y, Tanaka M, Nonaka K, Spork AP, Ducho C, Chen WC, Van Lanen SG. Structure-based gene targeting discovery of sphaerimicin, a bacterial translocase I inhibitor. Angewandte Chemie (International Ed. in English). 52: 11607-11. PMID 24014169 DOI: 10.1002/anie.201305546  0.52
2013 Chi X, Baba S, Tibrewal N, Funabashi M, Nonaka K, Van Lanen SG. The muraminomicin biosynthetic gene cluster and enzymatic formation of the 2-deoxyaminoribosyl appendage. Medchemcomm. 4: 239-243. PMID 23476724 DOI: 10.1039/C2MD20245J  0.52
2012 Barnard-Britson S, Chi X, Nonaka K, Spork AP, Tibrewal N, Goswami A, Pahari P, Ducho C, Rohr J, Van Lanen SG. Amalgamation of nucleosides and amino acids in antibiotic biosynthesis: discovery of an L-threonine:uridine-5'-aldehyde transaldolase. Journal of the American Chemical Society. 134: 18514-7. PMID 23110675 DOI: 10.1021/ja308185q  0.52
2012 Yang Z, Unrine J, Nonaka K, Van Lanen SG. Fe(II)-dependent, uridine-5'-monophosphate α-ketoglutarate dioxygenases in the synthesis of 5'-modified nucleosides. Methods in Enzymology. 516: 153-68. PMID 23034228 DOI: 10.1016/B978-0-12-394291-3.00031-9  0.52
2012 Tibrewal N, Downey TE, Van Lanen SG, Ul Sharif E, O'Doherty GA, Rohr J. Roles of the synergistic reductive O-methyltransferase GilM and of O-methyltransferase GilMT in the gilvocarcin biosynthetic pathway. Journal of the American Chemical Society. 134: 12402-5. PMID 22800463 DOI: 10.1021/ja305113d  0.52
2011 Koryakina I, Neville J, Nonaka K, Van Lanen SG, Williams GJ. A high-throughput screen for directed evolution of the natural product sulfotransferase LipB. Journal of Biomolecular Screening. 16: 845-51. PMID 21753186 DOI: 10.1177/1087057111413273  0.52
2011 Yang Z, Chi X, Funabashi M, Baba S, Nonaka K, Pahari P, Unrine J, Jacobsen JM, Elliott GI, Rohr J, Van Lanen SG. Characterization of LipL as a non-heme, Fe(II)-dependent α-ketoglutarate:UMP dioxygenase that generates uridine-5'-aldehyde during A-90289 biosynthesis. The Journal of Biological Chemistry. 286: 7885-92. PMID 21216959 DOI: 10.1074/jbc.M110.203562  0.52
2009 Van Lanen SG, Lin S, Horsman GP, Shen B. Characterization of SgcE6, the flavin reductase component supporting FAD-dependent halogenation and hydroxylation in the biosynthesis of the enediyne antitumor antibiotic C-1027. Fems Microbiology Letters. 300: 237-41. PMID 19817865 DOI: 10.1111/j.1574-6968.2009.01802.x  0.52
2009 Horsman GP, Van Lanen SG, Shen B. Iterative type I polyketide synthases for enediyne core biosynthesis. Methods in Enzymology. 459: 97-112. PMID 19362637 DOI: 10.1016/S0076-6879(09)04605-9  0.52
2009 Lin S, Van Lanen SG, Shen B. A free-standing condensation enzyme catalyzing ester bond formation in C-1027 biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 106: 4183-8. PMID 19246381 DOI: 10.1073/pnas.0808880106  0.52
2008 Jiang H, Zirkle R, Metz JG, Braun L, Richter L, Van Lanen SG, Shen B. The role of tandem acyl carrier protein domains in polyunsaturated fatty acid biosynthesis. Journal of the American Chemical Society. 130: 6336-7. PMID 18444614 DOI: 10.1021/ja801911t  0.52
2008 Zhang J, Van Lanen SG, Ju J, Liu W, Dorrestein PC, Li W, Kelleher NL, Shen B. A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 105: 1460-5. PMID 18223152 DOI: 10.1073/pnas.0711625105  0.52
2007 Lee BW, Van Lanen SG, Iwata-Reuyl D. Mechanistic studies of Bacillus subtilis QueF, the nitrile oxidoreductase involved in queuosine biosynthesis. Biochemistry. 46: 12844-54. PMID 17929836 DOI: 10.1021/bi701265r  1
2007 Cooke HA, Zhang J, Griffin MA, Nonaka K, Van Lanen SG, Shen B, Bruner SD. Characterization of NcsB2 as a promiscuous naphthoic acid/coenzyme A ligase integral to the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin. Journal of the American Chemical Society. 129: 7728-9. PMID 17539640 DOI: 10.1021/ja071886a  0.52
2007 Christianson CV, Montavon TJ, Van Lanen SG, Shen B, Bruner SD. The structure of L-tyrosine 2,3-aminomutase from the C-1027 enediyne antitumor antibiotic biosynthetic pathway. Biochemistry. 46: 7205-14. PMID 17516659 DOI: 10.1021/bi7003685  0.52
2006 Dorrestein PC, Van Lanen SG, Li W, Zhao C, Deng Z, Shen B, Kelleher NL. The bifunctional glyceryl transferase/phosphatase OzmB belonging to the HAD superfamily that diverts 1,3-bisphosphoglycerate into polyketide biosynthesis. Journal of the American Chemical Society. 128: 10386-7. PMID 16895402 DOI: 10.1021/ja0639362  0.52
2006 Van Lanen SG, Lin S, Dorrestein PC, Kelleher NL, Shen B. Substrate specificity of the adenylation enzyme SgcC1 involved in the biosynthesis of the enediyne antitumor antibiotic C-1027. The Journal of Biological Chemistry. 281: 29633-40. PMID 16887797 DOI: 10.1074/jbc.M605887200  0.52
2005 Swairjo MA, Reddy RR, Lee B, Van Lanen SG, Brown S, de Crécy-Lagard V, Iwata-Reuyl D, Schimmel P. Crystallization and preliminary X-ray characterization of the nitrile reductase QueF: a queuosine-biosynthesis enzyme. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 61: 945-8. PMID 16511203 DOI: 10.1107/S1744309105029246  0.52
2005 Van Lanen SG, Dorrestein PC, Christenson SD, Liu W, Ju J, Kelleher NL, Shen B. Biosynthesis of the beta-amino acid moiety of the enediyne antitumor antibiotic C-1027 featuring beta-amino acyl-S-carrier protein intermediates. Journal of the American Chemical Society. 127: 11594-5. PMID 16104723 DOI: 10.1021/ja052871k  0.52
2005 Liu W, Nonaka K, Nie L, Zhang J, Christenson SD, Bae J, Van Lanen SG, Zazopoulos E, Farnet CM, Yang CF, Shen B. The neocarzinostatin biosynthetic gene cluster from Streptomyces carzinostaticus ATCC 15944 involving two iterative type I polyketide synthases. Chemistry & Biology. 12: 293-302. PMID 15797213 DOI: 10.1016/j.chembiol.2004.12.013  0.52
2005 Van Lanen SG, Reader JS, Swairjo MA, de Crécy-Lagard V, Lee B, Iwata-Reuyl D. From cyclohydrolase to oxidoreductase: discovery of nitrile reductase activity in a common fold. Proceedings of the National Academy of Sciences of the United States of America. 102: 4264-9. PMID 15767583 DOI: 10.1073/pnas.0408056102  1
2005 Galm U, Hager MH, Van Lanen SG, Ju J, Thorson JS, Shen B. Antitumor antibiotics: bleomycin, enediynes, and mitomycin. Chemical Reviews. 105: 739-58. PMID 15700963 DOI: 10.1021/cr030117g  0.52
2003 Van Lanen SG, Iwata-Reuyl D. Kinetic mechanism of the tRNA-modifying enzyme S-adenosylmethionine:tRNA ribosyltransferase-isomerase (QueA). Biochemistry. 42: 5312-20. PMID 12731872 DOI: 10.1021/bi034197u  1
2003 Van Lanen SG, Kinzie SD, Matthieu S, Link T, Culp J, Iwata-Reuyl D. tRNA modification by S-adenosylmethionine:tRNA ribosyltransferase-isomerase. Assay development and characterization of the recombinant enzyme. The Journal of Biological Chemistry. 278: 10491-9. PMID 12533518 DOI: 10.1074/jbc.M207727200  0.52
2000 Bai Y, Fox DT, Lacy JA, Van Lanen SG, Iwata-Reuyl D. Hypermodification of tRNA in Thermophilic archaea. Cloning, overexpression, and characterization of tRNA-guanine transglycosylase from Methanococcus jannaschii. The Journal of Biological Chemistry. 275: 28731-8. PMID 10862614 DOI: 10.1074/jbc.M002174200  0.52
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