Year |
Citation |
Score |
2020 |
Tang B, Frasinyuk MS, Chikwana VM, Mahalingan KK, Morgan CA, Segvich DM, Bondarenko SP, Mrug GP, Wyrebek P, Watt DS, DePaoli-Roach AA, Roach PJ, Hurley TD. Discovery and development of small-molecule inhibitors of glycogen synthase. Journal of Medicinal Chemistry. PMID 32134266 DOI: 10.1021/acs.jmedchem.9b01851 |
0.359 |
|
2017 |
Fortea E, Lemieux V, Potvin L, Chikwana V, Griffin S, Hey T, McCaskill D, Narva K, Tan SY, Xu X, Vachon V, Schwartz JL. Cry6Aa1, a Bacillus thuringiensis Nematocidal and Insecticidal Toxin, Forms Pores in Planar Lipid Bilayers at Extremely Low Concentrations and Without the Need of Proteolytic Processing. The Journal of Biological Chemistry. PMID 28623231 DOI: 10.1074/Jbc.M116.765941 |
0.313 |
|
2016 |
Dementiev A, Board J, Sitaram A, Hey T, Kelker MS, Xu X, Hu Y, Vidal-Quist C, Chikwana V, Griffin S, McCaskill D, Wang NX, Hung SC, Chan MK, Lee MM, et al. The pesticidal Cry6Aa toxin from Bacillus thuringiensis is structurally similar to HlyE-family alpha pore-forming toxins. Bmc Biology. 14: 71. PMID 27576487 DOI: 10.1186/S12915-016-0295-9 |
0.327 |
|
2016 |
Contreras CJ, Segvich DM, Mahalingan K, Chikwana VM, Kirley TL, Hurley TD, DePaoli-Roach AA, Roach PJ. Incorporation of phosphate into glycogen by glycogen synthase. Archives of Biochemistry and Biophysics. PMID 27036853 DOI: 10.1016/J.Abb.2016.03.020 |
0.314 |
|
2013 |
Chikwana VM, Khanna M, Baskaran S, Tagliabracci VS, Contreras CJ, DePaoli-Roach A, Roach PJ, Hurley TD. Structural basis for 2'-phosphate incorporation into glycogen by glycogen synthase. Proceedings of the National Academy of Sciences of the United States of America. 110: 20976-81. PMID 24324135 DOI: 10.1073/Pnas.1310106111 |
0.406 |
|
2013 |
Khanna M, Imasaki T, Chikwana VM, Perez-Miller S, Hunter GO, Mosley A, Takagi Y, Hurley TD. Expression and purification of functional human glycogen synthase-1 (hGYS1) in insect cells. Protein Expression and Purification. 90: 78-83. PMID 23711380 DOI: 10.1016/J.Pep.2013.05.007 |
0.356 |
|
2012 |
Chikwana VM, Stec B, Lee BW, de Crécy-Lagard V, Iwata-Reuyl D, Swairjo MA. Structural basis of biological nitrile reduction. The Journal of Biological Chemistry. 287: 30560-70. PMID 22787148 DOI: 10.1074/Jbc.M112.388538 |
0.581 |
|
2011 |
Baskaran S, Chikwana VM, Contreras CJ, Davis KD, Wilson WA, DePaoli-Roach AA, Roach PJ, Hurley TD. Multiple glycogen-binding sites in eukaryotic glycogen synthase are required for high catalytic efficiency toward glycogen. The Journal of Biological Chemistry. 286: 33999-4006. PMID 21835915 DOI: 10.1074/Jbc.M111.264531 |
0.411 |
|
2011 |
Rakovich T, Boland C, Bernstein I, Chikwana VM, Iwata-Reuyl D, Kelly VP. Queuosine deficiency in eukaryotes compromises tyrosine production through increased tetrahydrobiopterin oxidation. The Journal of Biological Chemistry. 286: 19354-63. PMID 21487017 DOI: 10.1074/Jbc.M111.219576 |
0.561 |
|
2010 |
Phillips G, Chikwana VM, Maxwell A, El-Yacoubi B, Swairjo MA, Iwata-Reuyl D, de Crécy-Lagard V. Discovery and characterization of an amidinotransferase involved in the modification of archaeal tRNA. The Journal of Biological Chemistry. 285: 12706-13. PMID 20129918 DOI: 10.1074/Jbc.M110.102236 |
0.579 |
|
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