| Year |
Citation |
Score |
| 2023 |
Ivy ZK, Belcher JD, Khasabova IA, Chen C, Juliette JP, Abdulla FR, Ruan C, Allen K, Nguyen J, Rogness VM, Beckman JD, Khasabov SG, Gupta K, Taylor RP, Simone DA, ... Vercellotti GM, et al. Cold exposure induces vaso-occlusion and pain in sickle mice that depend on complement activation. Blood. PMID 37774369 DOI: 10.1182/blood.2022019282 |
0.687 |
|
| 2023 |
Belcher JD, Nataraja S, Abdulla F, Zhang P, Chen C, Nguyen J, Ruan C, Singh M, Demes S, Olson L, Stickens D, Stanwix J, Clarke E, Huang Y, Biddle M, ... Vercellotti GM, et al. The BACH1 inhibitor ASP8731 inhibits inflammation and vaso-occlusion and induces fetal hemoglobin in sickle cell disease. Frontiers in Medicine. 10: 1101501. PMID 37144034 DOI: 10.3389/fmed.2023.1101501 |
0.343 |
|
| 2023 |
Beckman JD, DaSilva A, Aronovich E, Nguyen A, Nguyen J, Hargis G, Reynolds D, Vercellotti GM, Betts B, Wood DK. JAK-STAT inhibition reduces endothelial pro-thrombotic activation and leukocyte- endothelial pro-adhesive interactions. Journal of Thrombosis and Haemostasis : Jth. PMID 36738826 DOI: 10.1016/j.jtha.2023.01.027 |
0.667 |
|
| 2023 |
Sparkenbaugh EM, Henderson MW, Miller-Awe MD, Abrams C, Ilich A, Trebak F, Ramadas N, Vital SA, Bohinc D, Bane K, Chen C, Patel M, Wallisch M, Renné T, Gruber A, ... ... Vercellotti GM, et al. Factor XII contributes to thrombotic complications and vaso-occlusion in sickle cell disease. Blood. PMID 36706361 DOI: 10.1182/blood.2022017074 |
0.311 |
|
| 2023 |
An R, Man Y, Cheng K, Zhang T, Chen C, Wang F, Abdulla F, Kucukal E, Wulftange WJ, Goreke U, Bode A, Nayak LV, Vercellotti GM, Belcher JD, Little JA, et al. Sickle red blood cell-derived extracellular vesicles activate endothelial cells and enhance sickle red cell adhesion mediated by von Willebrand factor. British Journal of Haematology. PMID 36604837 DOI: 10.1111/bjh.18616 |
0.324 |
|
| 2022 |
Belcher JD, Nguyen J, Chen C, Abdulla F, Conglin R, Ivy ZK, Cummings J, Dudler T, Vercellotti GM. MASP-2 and MASP-3 inhibitors block complement activation, inflammation, and microvascular stasis in a murine model of vaso-occlusion in sickle cell disease. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 35878790 DOI: 10.1016/j.trsl.2022.06.018 |
0.334 |
|
| 2022 |
Gentinetta T, Belcher JD, Brügger-Verdon V, Adam J, Ruthsatz T, Bain J, Schu D, Ventrici L, Edler M, Lioe H, Patel K, Chen C, Nguyen J, Abdulla F, Zhang P, ... ... Vercellotti GM, et al. Plasma-Derived Hemopexin as a Candidate Therapeutic Agent for Acute Vaso-Occlusion in Sickle Cell Disease: Preclinical Evidence. Journal of Clinical Medicine. 11. PMID 35160081 DOI: 10.3390/jcm11030630 |
0.337 |
|
| 2021 |
El Jurdi N, Elhusseini H, Beckman J, DeFor TE, Okoev G, Rogosheske J, Lazaryan A, Weiler K, Bachanova V, Betts BC, Blazar BR, Brunstein CG, He F, Holtan SG, Janakiram M, ... ... Vercellotti G, et al. High incidence of thromboembolism in patients with chronic GVHD: association with severity of GVHD and donor-recipient ABO blood group. Blood Cancer Journal. 11: 96. PMID 34006823 DOI: 10.1038/s41408-021-00488-2 |
0.647 |
|
| 2021 |
Zhang P, Nguyen J, Abdulla F, Nelson AT, Beckman JD, Vercellotti GM, Belcher JD. Soluble MD-2 and Heme in Sickle Cell Disease Plasma Promote Pro-Inflammatory Signaling in Endothelial Cells. Frontiers in Immunology. 12: 632709. PMID 33841413 DOI: 10.3389/fimmu.2021.632709 |
0.679 |
|
| 2020 |
Beckman JD, Abdullah F, Chen C, Kirchner R, Rivera-Rodriguez D, Kiser ZM, Nguyen A, Zhang P, Nguyen J, Hebbel RP, Belcher JD, Vercellotti GM. Endothelial TLR4 Expression Mediates Vaso-Occlusive Crisis in Sickle Cell Disease. Frontiers in Immunology. 11: 613278. PMID 33542720 DOI: 10.3389/fimmu.2020.613278 |
0.723 |
|
| 2020 |
Belcher JD, Zhang P, Nguyen J, Kiser ZM, Nath KA, Hu J, Trent JO, Vercellotti GM. Identification of a Heme Activation Site on the MD-2/TLR4 Complex. Frontiers in Immunology. 11: 1370. PMID 32695117 DOI: 10.1182/Blood-2019-123788 |
0.312 |
|
| 2020 |
Holtan SG, Hoeschen AL, Cao Q, Arora M, Bachanova V, Brunstein CG, Miller JS, Rashidi A, Slungaard A, Ustun C, Vercellotti GM, Warlick ED, Betts BC, El Jurdi N, He F, et al. Facilitating resolution of life-threatening acute GVHD with human chorionic gonadotropin and epidermal growth factor. Blood Advances. 4: 1284-1295. PMID 32236525 DOI: 10.1182/Bloodadvances.2019001259 |
0.318 |
|
| 2020 |
Hebbel RP, Belcher JD, Vercellotti GM. The multifaceted role of ischemia/reperfusion in sickle cell anemia. The Journal of Clinical Investigation. 130: 1062-1072. PMID 32118586 DOI: 10.1172/Jci133639 |
0.316 |
|
| 2020 |
Nath KA, Grande JP, Belcher JD, Garovic VD, Croatt AJ, Hillestad ML, Barry MA, Nath MC, Regan RF, Vercellotti GM. Antithrombotic Effects of Heme-Degrading and Heme-Binding Proteins. American Journal of Physiology. Heart and Circulatory Physiology. PMID 32004074 DOI: 10.1152/Ajpheart.00280.2019 |
0.374 |
|
| 2020 |
Sparkenbaugh EM, Chen C, Brzoska T, Nguyen J, Wang S, Vercellotti GM, Key NS, Sundd P, Belcher JD, Pawlinski R. Thrombin-mediated activation of PAR-1 contributes to microvascular stasis in mouse models of sickle cell disease. Blood. PMID 31977004 DOI: 10.1182/Blood.2019003543 |
0.438 |
|
| 2019 |
Kiser ZM, Lizcano A, Nguyen J, Becker GL, Belcher JD, Varki AP, Vercellotti GM. Decreased erythrocyte binding of Siglec-9 increases neutrophil activation in sickle cell disease. Blood Cells, Molecules & Diseases. 81: 102399. PMID 31901888 DOI: 10.1016/J.Bcmd.2019.102399 |
0.351 |
|
| 2019 |
Nath KA, Garovic VD, Grande JP, Croatt AJ, Ackerman AW, Farrugia G, Katusic ZS, Belcher JD, Vercellotti GM. Heme Oxygenase-2 Protects Against Ischemic Acute Kidney Injury: The Influence of Age and Sex. American Journal of Physiology. Renal Physiology. PMID 31215802 DOI: 10.1152/Ajprenal.00085.2019 |
0.364 |
|
| 2019 |
McArthur JG, Svenstrup N, Chen C, Fricot A, Carvalho C, Nguyen J, Nguyen P, Prachikova A, Abdulla F, Vercellotti GM, Hermine O, Edwards D, Ribeil JA, Belcher JD, Maciel TT. A novel, highly potent and selective phosphodiesterase-9 inhibitor for the treatment of sickle cell disease. Haematologica. PMID 31147439 DOI: 10.3324/Haematol.2018.213462 |
0.39 |
|
| 2019 |
Belcher JD, Biddle M, Stickens D, Olson L, Bell E, Chen C, Abdulla F, Nguyen J, Kiser ZM, Lloyd J, Vercellotti GM. Bach1 Inhibitors Reduce Stasis in Townes Sickle Cell Mouse Model Blood. 134: 983-983. DOI: 10.1182/Blood-2019-127300 |
0.421 |
|
| 2019 |
Belcher JD, Abdulla F, Chen C, Zhang P, Rivera-Rodriguez D, Kirchner R, Nguyen J, Kiser ZM, Nachbor K, Lloyd J, Vercellotti GM. Deletion of TLR4 in Townes SS Mice Prevents Microvascular Stasis in Response to Hemin, LPS and Hypoxia/Reoxygenation: Role of Inflammation Blood. 134: 3555-3555. DOI: 10.1182/Blood-2019-127114 |
0.342 |
|
| 2019 |
Zhang P, Belcher JD, Nguyen J, Abdulla F, Vercellotti GM. Increased Release of Soluble MD-2 in Sickle Cell Disease and Its Role in Pro-Inflammatory Signaling in Endothelial Cells Blood. 134: 208-208. DOI: 10.1182/Blood-2019-122912 |
0.365 |
|
| 2018 |
Vercellotti GM, Dalmasso AP, Schaid TR, Nguyen J, Chen C, Ericson ME, Abdulla F, Killeen T, Lindorfer MA, Taylor RP, Belcher JD. Critical role of C5a in sickle cell disease. American Journal of Hematology. PMID 30569594 DOI: 10.1002/Ajh.25384 |
0.41 |
|
| 2018 |
Telen MJ, Malik P, Vercellotti GM. Therapeutic strategies for sickle cell disease: towards a multi-agent approach. Nature Reviews. Drug Discovery. PMID 30514970 DOI: 10.1038/S41573-018-0003-2 |
0.31 |
|
| 2018 |
Jana S, Strader MB, Meng F, Hicks W, Kassa T, Tarandovskiy I, De Paoli S, Simak J, Heaven MR, Belcher JD, Vercellotti GM, Alayash AI. Hemoglobin oxidation-dependent reactions promote interactions with band 3 and oxidative changes in sickle cell-derived microparticles. Jci Insight. 3. PMID 30385713 DOI: 10.1172/Jci.Insight.120451 |
0.394 |
|
| 2018 |
Belcher JD, Gomperts E, Nguyen J, Chen C, Abdulla F, Kiser ZM, Gallo D, Levy H, Otterbein LE, Vercellotti GM. Oral carbon monoxide therapy in murine sickle cell disease: Beneficial effects on vaso-occlusion, inflammation and anemia. Plos One. 13: e0205194. PMID 30308028 DOI: 10.1371/Journal.Pone.0205194 |
0.423 |
|
| 2018 |
Belcher JD, Chen C, Nguyen J, Abdulla F, Zhang P, Nguyen H, Nguyen P, Killeen T, Miescher SM, Brinkman N, Nath KA, Steer CJ, Vercellotti GM. Haptoglobin and hemopexin inhibit vaso-occlusion and inflammation in murine sickle cell disease: Role of heme oxygenase-1 induction. Plos One. 13: e0196455. PMID 29694434 DOI: 10.1371/Journal.Pone.0196455 |
0.492 |
|
| 2018 |
Sparkenbaugh E, Chen C, Nguyen J, Wang S, Vercellotti GM, Belcher JD, Pawlinski R. Thrombin-mediated activation of par-1 contributes to microvascular stasis in mouse models of sickle cell disease via increased endothelial expression of p-selectin and vwf Blood. 132: 266-266. DOI: 10.1182/Blood-2018-99-116238 |
0.4 |
|
| 2018 |
Kiser ZM, Becker GL, Nguyen J, Lizcano A, Belcher JD, Varki AP, Vercellotti GM. Decreased Erythrocyte Binding Capability for Neutrophil Siglec-9 Is a Source of Oxidative Stress in Sickle Cell Disease Blood. 132: 3650-3650. DOI: 10.1182/Blood-2018-99-113579 |
0.327 |
|
| 2017 |
Louie JE, Anderson CJ, Fayaz M Fomani K, Henry A, Killeen T, Mohandas N, Yazdanbakhsh K, Belcher JD, Vercellotti GM, Shi PA. Case series supporting heme detoxification via therapeutic plasma exchange in acute multiorgan failure syndrome resistant to red blood cell exchange in sickle cell disease. Transfusion. PMID 29193101 DOI: 10.1111/Trf.14407 |
0.331 |
|
| 2017 |
Turcotte LM, DeFor TE, Newell LF, Cutler CS, Verneris MR, Wu J, Howard A, MacMillan ML, Antin JH, Vercellotti GM, Slungaard A, Blazar BR, Weisdorf DJ, Panoskaltsis-Mortari A, Holtan SG. Donor and recipient plasma follistatin levels are associated with acute GvHD in Blood and Marrow Transplant Clinical Trials Network 0402. Bone Marrow Transplantation. PMID 29058696 DOI: 10.1038/Bmt.2017.236 |
0.303 |
|
| 2017 |
Nath KA, Belcher JD, Nath MC, Grande JP, Croatt AJ, Ackerman AW, Katusic ZS, Vercellotti GM. The Role of TLR4 Signaling in the Nephrotoxicity of Heme and Heme Proteins. American Journal of Physiology. Renal Physiology. ajprenal.00432.2017. PMID 28978536 DOI: 10.1152/Ajprenal.00432.2017 |
0.36 |
|
| 2017 |
Solovey A, Somani A, Belcher JD, Milbauer L, Vincent L, Pawlinski R, Nath KA, Kelm RJ, Mackman N, O'Sullivan MG, Gupta K, Vercellotti GM, Hebbel RP. A monocyte-TNF-endothelial activation axis in sickle transgenic mice: Therapeutic benefit from TNF blockade. American Journal of Hematology. PMID 28699284 DOI: 10.1002/Ajh.24856 |
0.421 |
|
| 2017 |
Gomperts E, Belcher JD, Otterbein L, Coates T, Wood J, Skolnick BE, Levy H, Vercellotti GM. The Role of Carbon Monoxide and Heme Oxygenase in the Prevention of Sickle Cell Disease Vaso-Occlusive Crises. American Journal of Hematology. PMID 28378932 DOI: 10.1002/Ajh.24750 |
0.369 |
|
| 2016 |
Shi PA, Choi E, Chintagari NR, Nguyen J, Guo X, Yazdanbakhsh K, Mohandas N, Alayash AI, Manci EA, Belcher JD, Vercellotti GM. Sustained treatment of sickle cell mice with haptoglobin increases HO-1 and H-ferritin expression and decreases iron deposition in the kidney without improvement in kidney function. British Journal of Haematology. PMID 27507623 DOI: 10.1111/Bjh.14280 |
0.389 |
|
| 2016 |
Vercellotti GM, Zhang P, Nguyen J, Abdulla F, Chen C, Nguyen P, Nowotny C, Steer CJ, Smith A, Belcher JD. Hepatic Overexpression of Hemopexin Inhibits Inflammation and Vascular Stasis in Murine Models of Sickle Cell Disease. Molecular Medicine (Cambridge, Mass.). 22. PMID 27451971 DOI: 10.2119/Molmed.2016.00063 |
0.46 |
|
| 2016 |
Belcher JD, Chen C, Nguyen J, Zhang P, Abdulla F, Nguyen P, Killeen T, Xu P, O'Sullivan G, Nath K, Vercellotti G. Control of oxidative stress and inflammation in sickle cell disease with the Nrf2 activator dimethyl fumarate. Antioxidants & Redox Signaling. PMID 26914345 DOI: 10.1089/Ars.2015.6571 |
0.37 |
|
| 2016 |
Jana S, Strader MB, Kassa T, Meng F, Hicks W, Tarandovskiy I, De Paoli S, Simak J, Miller JL, Mendelsohn L, Nichols J, Thein SL, Belcher JD, Vercellotti GM, Alayash A. Hemoglobin S Oxidation Promotes Plasma-Derived Microparticle Membrane Alterations and Toxicity Blood. 128: 856-856. DOI: 10.1182/Blood.V128.22.856.856 |
0.424 |
|
| 2016 |
Santiago RP, Guarda CC, Figueiredo CVB, Fiuza LM, Adanho CSA, Aleluia MM, Zanette DL, Carvalho MOS, Lyra IM, Lopes VM, Nguyen J, Killeen T, Nguyen H, Vercellotti GM, Belcher JD, et al. Serum Haptoglobin and Hemopexin Levels in Pediatric SS and SC Disease Patients: Biomarker of Hemolysis and Inflammation Blood. 128: 3649-3649. DOI: 10.1182/Blood.V128.22.3649.3649 |
0.339 |
|
| 2016 |
McArthur JG, Maciel T, Chen C, Fricot A, Kobayashi D, Nguyen J, Nguyen P, Parachova A, Abdulla F, Vercellotti GM, Svenstrup N, Belcher JD. A Novel, Highly Potent and Selective PDE9 Inhibitor for the Treatment of Sickle Cell Disease Blood. 128: 268-268. DOI: 10.1182/Blood.V128.22.268.268 |
0.386 |
|
| 2016 |
Belcher JD, Chen C, Nguyen J, Abdulla F, Nguyen P, Nguyen H, Zhang P, Brinkman N, Vercellotti GM. Haptoglobin and Hemopexin Infusion Efficiently Activates the Nrf2/HO-1 Axis and Inhibits Inflammation and Vaso-Occlusion in Murine Sickle Cell Disease Blood. 128: 2477-2477. DOI: 10.1182/Blood.V128.22.2477.2477 |
0.448 |
|
| 2016 |
Vinchi F, Vercellotti GM, Belcher JD, Fibach E, Zreid H, Rasras R, Ghoti H, Muckenthaler MU, Rachmilewitz EA. Systemic Heme and Iron Overload Results in Depletion of Serum Hemopexin, Haptoglobin and Transferrin and Correlates with Markers of Endothelial Activation and Lipid Oxidation in Beta Thalassemia Major and Intermedia Blood. 128: 2469-2469. DOI: 10.1182/Blood.V128.22.2469.2469 |
0.36 |
|
| 2016 |
Schaid TR, Nguyen J, Chen C, Abdulla F, Killeen T, Nguyen H, Edmund J, Lindorfer MA, Taylor RP, Dalmasso AP, Belcher JD, Vercellotti GM. Complement Activation in a Murine Model of Sickle Cell Disease: Inhibition of Vaso-Occlusion By Blocking C5 Activation Blood. 128: 158-158. DOI: 10.1182/Blood.V128.22.158.158 |
0.39 |
|
| 2015 |
Vercellotti GM. Special delivery: microparticles convey heme. Blood. 125: 3677-8. PMID 26069333 DOI: 10.1182/Blood-2015-04-639484 |
0.348 |
|
| 2015 |
Holtan SG, Verneris MR, Schultz KR, Newell LF, Meyers G, He F, DeFor TE, Vercellotti GM, Slungaard A, MacMillan ML, Cooley SA, Blazar BR, Panoskaltsis-Mortari A, Weisdorf DJ. Circulating angiogenic factors associated with response and survival in patients with acute graft-versus-host disease: results from Blood and Marrow Transplant Clinical Trials Network 0302 and 0802. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 21: 1029-36. PMID 25759146 DOI: 10.1016/J.Bbmt.2015.02.018 |
0.328 |
|
| 2015 |
Belcher JD, Chen C, Nguyen J, Abdulla F, Nguyen P, Nguyen M, Okeley NM, Benjamin DR, Senter PD, Vercellotti GM. The fucosylation inhibitor, 2-fluorofucose, inhibits vaso-occlusion, leukocyte-endothelium interactions and NF-ĸB activation in transgenic sickle mice. Plos One. 10: e0117772. PMID 25706118 DOI: 10.1371/Journal.Pone.0117772 |
0.459 |
|
| 2015 |
Chintagari NR, Nguyen J, Belcher JD, Vercellotti GM, Alayash AI. Haptoglobin attenuates hemoglobin-induced heme oxygenase-1 in renal proximal tubule cells and kidneys of a mouse model of sickle cell disease. Blood Cells, Molecules & Diseases. 54: 302-6. PMID 25582460 DOI: 10.1016/J.Bcmd.2014.12.001 |
0.394 |
|
| 2015 |
Vercellotti GM, Zhang P, Chen C, Nguyen J, Abdulla F, Nguyen P, Nowotny C, Irfanullah A, Smith A, Steer CJ, Belcher JD. Hemopexin Gene Therapy Inhibits Inflammation and Vaso-Occlusion in Transgenic Sickle Cell Mice Blood. 126: 412-412. DOI: 10.1182/Blood.V126.23.412.412 |
0.451 |
|
| 2015 |
Cataldo G, Lunzer MM, Simone DA, Akgün E, Belcher JD, Vercellotti GM, Portoghese PS. Targeting Putative Mu Opioid/Chemokine Receptor Type 5 Heteromers Potently Attenuates Nociception in a Murine Model of Sickle Cell Disease Blood. 126: 277-277. DOI: 10.1182/Blood.V126.23.277.277 |
0.366 |
|
| 2015 |
Shi PA, Choi E, Nguyen J, Guo X, Mohandas N, Alayash A, Manci E, Belcher JD, Vercellotti GM. Three Months of Human Haptoglobin Treatment Decreases Iron Deposition in the Kidneys of Townes Sickle Mice Blood. 126: 2163-2163. DOI: 10.1182/Blood.V126.23.2163.2163 |
0.4 |
|
| 2014 |
Vercellotti GM. Look out heme, Mac is back in town. Blood. 124: 1388-9. PMID 25170114 DOI: 10.1182/Blood-2014-07-585950 |
0.343 |
|
| 2014 |
Vercellotti GM, Khan FB, Nguyen J, Chen C, Bruzzone CM, Bechtel H, Brown G, Nath KA, Steer CJ, Hebbel RP, Belcher JD. H-ferritin ferroxidase induces cytoprotective pathways and inhibits microvascular stasis in transgenic sickle mice. Frontiers in Pharmacology. 5: 79. PMID 24860503 DOI: 10.3389/Fphar.2014.00079 |
0.452 |
|
| 2014 |
Khan F, Linden MA, Zantek ND, Vercellotti GM. Subcutaneous bortezomib is highly effective for pure red cell aplasia after ABO-incompatible haematopoietic stem cell transplantation Transfusion Medicine. 24: 187-188. PMID 24809981 DOI: 10.1111/Tme.12121 |
0.358 |
|
| 2014 |
Vercellotti GM, Belcher JD. Not simply misshapen red cells: multimolecular and cellular events in sickle vaso-occlusion. The Journal of Clinical Investigation. 124: 1462-5. PMID 24642460 DOI: 10.1172/Jci75238 |
0.386 |
|
| 2014 |
Belcher JD, Chen C, Nguyen J, Milbauer L, Abdulla F, Alayash AI, Smith A, Nath KA, Hebbel RP, Vercellotti GM. Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease. Blood. 123: 377-90. PMID 24277079 DOI: 10.1182/Blood-2013-04-495887 |
0.419 |
|
| 2014 |
Belcher JD, Nguyen J, Chen C, Abdulla F, Nguyen P, Nguyen M, Zhang P, Xu P, Slipek NJ, Vercellotti GM. Dimethyl Fumarate Induces Cytoprotection and Inhibits Inflammation and Vaso-Occlusion in Transgenic Sickle Mice Blood. 124: 219-219. DOI: 10.1182/Blood.V124.21.219.219 |
0.47 |
|
| 2013 |
Belcher JD, Nath KA, Vercellotti GM. Vasculotoxic and Proinflammatory Effects of Plasma Heme: Cell Signaling and Cytoprotective Responses. Isrn Oxidative Medicine. 2013. PMID 25506596 DOI: 10.1155/2013/831596 |
0.361 |
|
| 2013 |
Sjeklocha LM, Wong PY, Belcher JD, Vercellotti GM, Steer CJ. β-Globin sleeping beauty transposon reduces red blood cell sickling in a patient-derived CD34(+)-based in vitro model. Plos One. 8: e80403. PMID 24260386 DOI: 10.1371/Journal.Pone.0080403 |
0.333 |
|
| 2013 |
Wegiel B, Gallo D, Csizmadia E, Harris C, Belcher J, Vercellotti GM, Penacho N, Seth P, Sukhatme V, Ahmed A, Pandolfi PP, Helczynski L, Bjartell A, Persson JL, Otterbein LE. Carbon monoxide expedites metabolic exhaustion to inhibit tumor growth. Cancer Research. 73: 7009-21. PMID 24121491 DOI: 10.1158/0008-5472.Can-13-1075 |
0.305 |
|
| 2013 |
Belcher JD, Young M, Chen C, Nguyen J, Burhop K, Tran P, Vercellotti GM. MP4CO, a pegylated hemoglobin saturated with carbon monoxide, is a modulator of HO-1, inflammation, and vaso-occlusion in transgenic sickle mice. Blood. 122: 2757-64. PMID 23908468 DOI: 10.1182/Blood-2013-02-486282 |
0.428 |
|
| 2013 |
Schaer DJ, Buehler PW, Alayash AI, Belcher JD, Vercellotti GM. Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins. Blood. 121: 1276-84. PMID 23264591 DOI: 10.1182/Blood-2012-11-451229 |
0.373 |
|
| 2013 |
Nath KA, Grande JP, Farrugia G, Croatt AJ, Belcher JD, Hebbel RP, Vercellotti GM, Katusic ZS. Age sensitizes the kidney to heme protein-induced acute kidney injury. American Journal of Physiology. Renal Physiology. 304: F317-25. PMID 23195679 DOI: 10.1152/Ajprenal.00606.2012 |
0.38 |
|
| 2013 |
Belcher JD, Chen C, Nguyen J, Okeley NM, Senter PD, Benjamin DR, Vercellotti GM. Fucosylation Inhibitor, 2-Fluorofucose, Inhibits NF-κB Activation and Vaso-Occlusion In Transgenic Sickle Mice Blood. 122: 730-730. DOI: 10.1182/Blood.V122.21.730.730 |
0.425 |
|
| 2013 |
Solovey A, Somani A, Chen C, Kiley J, Marker P, Abdulla F, O'Sullivan MG, Kelm RJ, Belcher JD, Vercellotti GM, Hebbel RP. Interference With TNFα Using Long-Term Etanercept In S+SAntilles Sickle Transgenic Mice Ameliorates Abnormal Endothelial Activation, Vasoocclusion, and Pulmonary Hypertension Including Its Pulmonary Arterial Wall Remodeling Blood. 122: 728-728. DOI: 10.1182/Blood.V122.21.728.728 |
0.409 |
|
| 2013 |
Khan F, Linden MA, Zantek ND, Vercellotti GM. Bortezomib Is Highly Effective For Pure Red Cell Aplasia After ABO-Incompatible Hematopoietic Stem Cell Transplantation Blood. 122: 5495-5495. DOI: 10.1182/Blood.V122.21.5495.5495 |
0.355 |
|
| 2013 |
Mathson K, Teena R, Belcher JD, Vercellotti GM, Slungaard A. Thiocyanate Blocks Peroxidase-Dependent Extracellular Trap (ET) Formation By PMN and Eosinophils: Heme Is a Potent New Agonist For The ET Pathway Blood. 122: 323-323. DOI: 10.1182/Blood.V122.21.323.323 |
0.333 |
|
| 2013 |
Rehani T, Mathson K, Belcher JD, Vercellotti GM, Slungaard A. Heme Potently Stimulates Tissue Factor Expression By Peripheral Blood Monocytes: A Novel Mechanism For Thrombosis In Intravascular Hemolytic Diseases Blood. 122: 2215-2215. DOI: 10.1182/Blood.V122.21.2215.2215 |
0.387 |
|
| 2013 |
Ustun C, Reiter A, Scott BL, Nakamura R, Gandhi D, Kreil S, Shanley R, Hogan WJ, Perales M, Shore TB, Baurmann H, Stuart RK, Gruhn B, Doubek M, Hsu JW, ... ... Vercellotti GM, et al. Allogeneic Hematopoietic Cell Transplantation Is Effective In Patients With Advanced Systemic Mastocytosis: A Multicenter Retrospective Analysis Blood. 122: 2145-2145. DOI: 10.1182/Blood.V122.21.2145.2145 |
0.314 |
|
| 2012 |
Vercellotti GM, Moldow CF, Jacob HS. Complement, oxidants, and endothelial injury: how a bedside observation opened a door to vascular biology. The Journal of Clinical Investigation. 122: 3044-5. PMID 23106086 DOI: 10.1172/Jci64953 |
0.316 |
|
| 2012 |
Vercellotti GM, Chen C, Bruzzone CM, Bechtel HA, Ngyuen J, Hebbel RP, Steer CJ, Belcher JD. H-Ferritin Ferroxidase Activity Induces Cytoprotective Pathways and Inhibits Microvascular Stasis in Transgenic Sickle Mice Blood. 120: 378-378. DOI: 10.1182/Blood.V120.21.378.378 |
0.445 |
|
| 2012 |
Belcher JD, Chen C, Young M, Burhop K, Vercellotti GM. MP4CO, a Pegylated Hemoglobin Saturated with Carbon Monoxide, Inhibits Microvascular Stasis in Transgenic Sickle Mice Through Heme Oxygenase-1. Blood. 120: 2112-2112. DOI: 10.1182/Blood.V120.21.2112.2112 |
0.43 |
|
| 2011 |
Sjeklocha LM, Park CW, Wong PY, Roney MJ, Belcher JD, Kaufman DS, Vercellotti GM, Hebbel RP, Steer CJ. Erythroid-specific expression of β-globin from Sleeping Beauty-transduced human hematopoietic progenitor cells. Plos One. 6: e29110. PMID 22216176 DOI: 10.1371/Journal.Pone.0029110 |
0.301 |
|
| 2011 |
Kang L, Yamada S, Hernandez MC, Croatt AJ, Grande JP, Juncos JP, Vercellotti GM, Hebbel RP, Katusic ZS, Terzic A, Nath KA. Regional and systemic hemodynamic responses following the creation of a murine arteriovenous fistula. American Journal of Physiology. Renal Physiology. 301: F845-51. PMID 21697243 DOI: 10.1152/Ajprenal.00311.2011 |
0.326 |
|
| 2011 |
Juncos R, Juncos L, Hebbel RP, Vercellotti GM, Katusic ZS, Nath KA. Selective enhancement of contractions to α1-adrenergic receptor activation in the aorta of mice with sickle cell disease. Journal of Cardiovascular Pharmacology. 57: 263-6. PMID 21107280 DOI: 10.1097/Fjc.0B013E318204Bb34 |
0.343 |
|
| 2011 |
Beckman JD, Chen C, Nguyen J, Thayanithy V, Subramanian S, Steer CJ, Vercellotti GM. Regulation of heme oxygenase-1 protein expression by miR-377 in combination with miR-217. The Journal of Biological Chemistry. 286: 3194-202. PMID 21106538 DOI: 10.1074/Jbc.M110.148726 |
0.641 |
|
| 2011 |
Belcher JD, Nguyen J, Chen C, Smith A, Alayash AI, Nair SL, Somani A, Hebbel RP, Vercellotti GM. Plasma Hemoglobin and Heme Trigger Weibel Palade Body Exocytosis and Vaso-Occlusion in Transgenic Sickle Mice Blood. 118: 896-896. DOI: 10.1182/Blood.V118.21.896.896 |
0.473 |
|
| 2011 |
Belcher JD, Chen C, Young M, Tran P, Vercellotti GM. Prevention of Venular Stasis, Circulatory Collapse and Mortality in Transgenic Sickle Mice Administered MP4CO, a Pegylated Hemoglobin Saturated with Carbon Monoxide Blood. 118: 850-850. DOI: 10.1182/Blood.V118.21.850.850 |
0.421 |
|
| 2011 |
Beckman JD, Marker PH, Nguyen J, Belcher JD, Croatt AJ, Nath KA, Hebbel RP, Vercellotti GM. Carbon Monoxide Therapy Modulates Hematopoietic Stem Cell Development in Heme-Oxygenase-1 Knockout Mice Blood. 118: 1318-1318. DOI: 10.1182/Blood.V118.21.1318.1318 |
0.728 |
|
| 2011 |
Solovey A, Chang LM, Abdulla F, Kollander R, Marker PH, Kelm R, Vercellotti GM, Hebbel RP. The Blood Monocyte - TNF - Endothelial Axis in Activation of Endothelial Tissue Factor in the Transgenic Sickle Mouse: Possible Relevance of Etanercept to Sickle Coagulopathy Blood. 118: 1048-1048. DOI: 10.1182/Blood.V118.21.1048.1048 |
0.393 |
|
| 2010 |
Jiang J, Goel R, Schmechel S, Vercellotti G, Forster C, Bischof J. Pre-conditioning cryosurgery: cellular and molecular mechanisms and dynamics of TNF-α enhanced cryotherapy in an in vivo prostate cancer model system. Cryobiology. 61: 280-8. PMID 20940007 DOI: 10.1016/J.Cryobiol.2010.09.006 |
0.318 |
|
| 2010 |
Sheng WS, Hu S, Nettles AR, Lokensgard JR, Vercellotti GM, Rock RB. Hemin inhibits NO production by IL-1β-stimulated human astrocytes through induction of heme oxygenase-1 and reduction of p38 MAPK activation. Journal of Neuroinflammation. 7: 51. PMID 20822529 DOI: 10.1186/1742-2094-7-51 |
0.34 |
|
| 2010 |
Nagy E, Eaton JW, Jeney V, Soares MP, Varga Z, Galajda Z, Szentmiklósi J, Méhes G, Csonka T, Smith A, Vercellotti GM, Balla G, Balla J. Red cells, hemoglobin, heme, iron, and atherogenesis. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 1347-53. PMID 20378845 DOI: 10.1161/Atvbaha.110.206433 |
0.314 |
|
| 2010 |
Belcher JD, Vineyard JV, Bruzzone CM, Chen C, Beckman JD, Nguyen J, Steer CJ, Vercellotti GM. Heme oxygenase-1 gene delivery by Sleeping Beauty inhibits vascular stasis in a murine model of sickle cell disease. Journal of Molecular Medicine (Berlin, Germany). 88: 665-75. PMID 20306336 DOI: 10.1007/S00109-010-0613-6 |
0.741 |
|
| 2010 |
Juncos JP, Grande JP, Croatt AJ, Hebbel RP, Vercellotti GM, Katusic ZS, Nath KA. Early and prominent alterations in hemodynamics, signaling, and gene expression following renal ischemia in sickle cell disease. American Journal of Physiology. Renal Physiology. 298: F892-9. PMID 20107113 DOI: 10.1152/Ajprenal.00631.2009 |
0.375 |
|
| 2010 |
Hebbel RP, Vercellotti GM, Pace BS, Solovey AN, Kollander R, Abanonu CF, Nguyen J, Vineyard JV, Belcher JD, Abdulla F, Osifuye S, Eaton JW, Kelm RJ, Slungaard A. The HDAC inhibitors trichostatin A and suberoylanilide hydroxamic acid exhibit multiple modalities of benefit for the vascular pathobiology of sickle transgenic mice. Blood. 115: 2483-90. PMID 20053759 DOI: 10.1182/Blood-2009-02-204990 |
0.434 |
|
| 2010 |
Belcher JD, Beckman JD, Balla G, Balla J, Vercellotti G. Heme degradation and vascular injury. Antioxidants & Redox Signaling. 12: 233-48. PMID 19697995 DOI: 10.1089/Ars.2009.2822 |
0.705 |
|
| 2010 |
Vercellotti GM, Belcher JD. Heme and the Vasculature: How the Endothelium Protects Itself Against Toxic Iron Blood. 116: SCI-25-SCI-25. DOI: 10.1182/Blood.V116.21.Sci-25.Sci-25 |
0.457 |
|
| 2010 |
Beckman JD, Marker PH, Nguyen J, Belcher JD, Hebbel RP, Croatt AJ, Nath KA, Vercellotti GM. Carbon Monoxide Therapy Reduces Reactive Oxygen Species Production and the Short-Term Hematopoietic Stem Cell Population In Heme-Oxygenase-1 Knockout Mice Blood. 116: 4767-4767. DOI: 10.1182/Blood.V116.21.4767.4767 |
0.73 |
|
| 2010 |
Romee R, Weisdorf DJ, Brunstein C, Wagner JE, Blazar BR, Majhail NS, Vercellotti GM, Miller JS, Arora M. ABO Mismatch Adversely Affects GvHD In Recipients of HLA Matched Unrelated Marrow or Peripheral Blood but Not Single or Double Umbilical Cord Blood Transplants Blood. 116: 226-226. DOI: 10.1182/Blood.V116.21.226.226 |
0.306 |
|
| 2010 |
Belcher JD, Nguyen J, Furne J, Vineyard J, Beckman JD, Marker PH, Hebbel RP, Levitt MD, Vercellotti GM. Exhaled Carbon Monoxide as a Marker of Hemolysis In Transgenic Mouse Models of Sickle Cell Anemia. Blood. 116: 1642-1642. DOI: 10.1182/Blood.V116.21.1642.1642 |
0.733 |
|
| 2010 |
Wasiluk KR, Goldish D, Benson BA, Vercellotti G, Dalmasso AP. IL-4 induces up-regulation of the junction protein claudin-5 in vascular endothelial cells, which is required for protection from killing by the membrane attack complex Molecular Immunology. 47: 2226-2226. DOI: 10.1016/J.Molimm.2010.05.091 |
0.304 |
|
| 2009 |
Hebbel RP, Vercellotti G, Nath KA. A systems biology consideration of the vasculopathy of sickle cell anemia: the need for multi-modality chemo-prophylaxsis. Cardiovascular & Hematological Disorders Drug Targets. 9: 271-92. PMID 19751187 DOI: 10.2174/1871529X10909040271 |
0.34 |
|
| 2009 |
Beckman JD, Belcher JD, Vineyard JV, Chen C, Nguyen J, Nwaneri MO, O'Sullivan MG, Gulbahce E, Hebbel RP, Vercellotti GM. Inhaled carbon monoxide reduces leukocytosis in a murine model of sickle cell disease. American Journal of Physiology. Heart and Circulatory Physiology. 297: H1243-53. PMID 19617415 DOI: 10.1152/Ajpheart.00327.2009 |
0.74 |
|
| 2009 |
Jeney V, Komódi E, Nagy E, Zarjou A, Vercellotti GM, Eaton JW, Balla G, Balla J. Supression of hemin-mediated oxidation of low-density lipoprotein and subsequent endothelial reactions by hydrogen sulfide (H(2)S). Free Radical Biology & Medicine. 46: 616-23. PMID 19100829 DOI: 10.1016/J.Freeradbiomed.2008.11.018 |
0.312 |
|
| 2009 |
Hebbel RP, Vercellotti GM, Pace B, Solovey A, Kollander R, Abanonu C, Nguyen J, Vineyard JV, Belcher JD, Abdulla F, Osifuye S, Eaton JW, Kelm R, Slungaard A. The HDAC Inhibitors Trichostatin A (TSA) and Suberoylanilide Hydroxamic Acid (SAHA) Exhibit Multiple Modalities of Benefit for the Vascular Pathology of Sickle Disease. Blood. 114: 2586-2586. DOI: 10.1182/Blood.V114.22.2586.2586 |
0.377 |
|
| 2009 |
Belcher BD, Vineyard JV, Bruzzone CM, Chen C, Beckman JD, Ngyuen J, Steer CJ, Vercellotti GM. Heme Oxygenase-1 Gene Therapy in a Murine Model of Sickle Cell Disease. Blood. 114: 1527-1527. DOI: 10.1182/Blood.V114.22.1527.1527 |
0.73 |
|
| 2009 |
Wegiel B, Bjartell A, Harris C, Belcher J, Vercellotti G, Gallo D, Csizmadia E, Helczynski L, Persson JL, Otterbein LE. Abstract C41: Heme oxygenase‐1 and carbon monoxide modulate responses to DNA damage in prostate cancer Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-C41 |
0.335 |
|
| 2008 |
Bruzzone CM, Belcher JD, Schuld NJ, Newman KA, Vineyard J, Nguyen J, Chen C, Beckman JD, Steer CJ, Vercellotti GM. Quantitative real-time polymerase chain reaction (qRT-PCR) restriction fragment length polymorphism (RFLP) method for monitoring highly conserved transgene expression during gene therapy. Translational Research : the Journal of Laboratory and Clinical Medicine. 152: 290-7. PMID 19059164 DOI: 10.1016/J.Trsl.2008.10.005 |
0.685 |
|
| 2008 |
Wudhikarn K, Vercellotti GM, Arora M. Hypocalcemia during Autologous Stem Cell Transplant with Concurrent Biphosphonate Use in Patients with Multiple Myeloma Blood. 112: 4335-4335. DOI: 10.1182/Blood.V112.11.4335.4335 |
0.307 |
|
| 2008 |
Yang C, Beckman JD, Schmidt TE, Nguyen J, Belcher JD, Vercellotti GM. Potential Role of Heme Oxygenase-1 in Arsenic Trioxide and Hemin-Mediated Differentiation of Human Promyelocytic Leukemia Cells Blood. 112: 3981-3981. DOI: 10.1182/Blood.V112.11.3981.3981 |
0.71 |
|
| 2008 |
Beckman JD, Vineyard JV, Chen C, Ngyuen J, Nwaneri MO, Marker P, Belcher JD, Vercellotti GM. Carbon Monoxide Decreases Leukocytosis in Murine Sickle Cell Disease Models Via Decreased Granulopoiesis. Blood. 112: 1433-1433. DOI: 10.1182/Blood.V112.11.1433.1433 |
0.737 |
|
| 2008 |
Pasrija T, Mahmud SA, Belcher JD, Vercellotti GM, Slungaard A. Gene-Specific Effects of the Histone Deacetylase Inhibitor TSA on Activation of a Pro-Inflammatory Endothelial Cell Phenotype by the Major Phagocyte Peroxidase-Derived Oxidant HOSCN. Blood. 112: 1274-1274. DOI: 10.1182/Blood.V112.11.1274.1274 |
0.379 |
|
| 2007 |
Balla J, Vercellotti GM, Jeney V, Yachie A, Varga Z, Jacob HS, Eaton JW, Balla G. Heme, heme oxygenase, and ferritin: how the vascular endothelium survives (and dies) in an iron-rich environment. Antioxidants & Redox Signaling. 9: 2119-37. PMID 17767398 DOI: 10.1089/Ars.2007.1787 |
0.371 |
|
| 2007 |
Mahmud SA, Wang J, Wei P, Thomas MS, Belcher JD, Vercellotti GM, Slungaard A. The Major Phagocyte Peroxidase-Derived Oxidant, HOSCN (Hypothiocyanous Acid), Induces Proinflammatory and Cytoprotective Gene Expression in Endothelium: A Mechanism for Microlocalized Regulation of Inflammation. Blood. 110: 3295-3295. DOI: 10.1182/Blood.V110.11.3295.3295 |
0.401 |
|
| 2007 |
Beckman JD, Vineyard JV, Yang C, Schmidt TE, Belcher JD, Vercellotti GM. Inhaled Carbon Monoxide: An Anti-Inflammatory Modulator in Transgenic Sickle Mice. Blood. 110: 2268-2268. DOI: 10.1182/Blood.V110.11.2268.2268 |
0.734 |
|
| 2007 |
Bruzzone CM, Newman KA, Belcher JD, Steer CJ, Vercellotti GM. Differentiation of Highly Conserved Host and Transgene mRNA in HO-1 Gene Therapy. Blood. 110: 2266-2266. DOI: 10.1182/Blood.V110.11.2266.2266 |
0.316 |
|
| 2006 |
Kaul DK, Kollander R, Mahaseth H, Liu XD, Solovey A, Belcher J, Kelm RJ, Vercellotti GM, Hebbel RP. Robust vascular protective effect of hydroxamic acid derivatives in a sickle mouse model of inflammation. Microcirculation (New York, N.Y. : 1994). 13: 489-97. PMID 16864415 DOI: 10.1080/10739680600778456 |
0.366 |
|
| 2006 |
Wang J, Shen YH, Utama B, LeMaire SA, Coselli JS, Vercellotti GM, Wang XL. HCMV infection attenuates hydrogen peroxide induced endothelial apoptosis - involvement of ERK pathway Febs Letters. 580: 2779-2787. PMID 16650413 DOI: 10.1016/J.Febslet.2006.04.041 |
0.343 |
|
| 2006 |
Belcher JD, Mahaseth H, Welch TE, Otterbein LE, Hebbel RP, Vercellotti GM. Heme oxygenase-1 is a modulator of inflammation and vaso-occlusion in transgenic sickle mice. The Journal of Clinical Investigation. 116: 808-16. PMID 16485041 DOI: 10.1172/Jci26857 |
0.425 |
|
| 2006 |
Ujhelyi L, Balla G, Jeney V, Varga Z, Nagy E, Vercellotti GM, Agarwal A, Eaton JW, Balla J. Hemodialysis reduces inhibitory effect of plasma ultrafiltrate on LDL oxidation and subsequent endothelial reactions Kidney International. 69: 144-151. PMID 16374435 DOI: 10.1038/Sj.Ki.5000007 |
0.366 |
|
| 2006 |
Ujhelyi L, Balla G, Jeney V, Varga Z, Nagy E, Vercellotti GM, Agarwal A, Eaton JW, Balla J. Response to p-Cresol for better or worse: But what are we measuring? [5] Kidney International. 70: 232-233. DOI: 10.1038/Sj.Ki.5001531 |
0.322 |
|
| 2005 |
Nagy E, Jeney V, Yachie A, Szabó RP, Wagner O, Vercellotti GM, Eaton JW, Balla G, Balla J. Oxidation of hemoglobin by lipid hydroperoxide associated with low-density lipoprotein (LDL) and increased cytotoxic effect by LDL oxidation in heme oxygenase-1 (HO-1) deficiency Cellular and Molecular Biology. 51: 377-385. PMID 16309588 DOI: 10.1170/T641 |
0.329 |
|
| 2005 |
Balla J, Vercellotti GM, Jeney V, Yachie A, Varga Z, Eaton JW, Balla G. Heme, heme oxygenase and ferritin in vascular endothelial cell injury. Molecular Nutrition & Food Research. 49: 1030-43. PMID 16208635 DOI: 10.1002/Mnfr.200500076 |
0.391 |
|
| 2005 |
Mahaseth H, Vercellotti GM, Welch TE, Bowlin PR, Sonbol KM, Hsia CJ, Li M, Bischof JC, Hebbel RP, Belcher JD. Polynitroxyl albumin inhibits inflammation and vasoocclusion in transgenic sickle mice. The Journal of Laboratory and Clinical Medicine. 145: 204-11. PMID 15962839 DOI: 10.1016/J.Lab.2005.02.008 |
0.432 |
|
| 2005 |
Belcher JD, Mahaseth H, Welch TE, Vilback AE, Sonbol KM, Kalambur VS, Bowlin PR, Bischof JC, Hebbel RP, Vercellotti GM. Critical role of endothelial cell activation in hypoxia-induced vasoocclusion in transgenic sickle mice. American Journal of Physiology. Heart and Circulatory Physiology. 288: H2715-25. PMID 15665055 DOI: 10.1152/Ajpheart.00986.2004 |
0.459 |
|
| 2005 |
Belcher JD, Mahaseth H, Welch TE, Boakye-Agyeman F, Hebbel RP, Vercellotti GM. Oxidative Stress and Vaso-Occlusion in Sickle Cell Disease: Role of Activated Leukocytes and Redox Active Iron. Blood. 106: 3165-3165. DOI: 10.1182/Blood.V106.11.3165.3165 |
0.465 |
|
| 2004 |
Kalambur VS, Mahaseth H, Bischof JC, Kielbik MC, Welch TE, Vilbäck A, Swanlund DJ, Hebbel RP, Belcher JD, Vercellotti GM. Microvascular blood flow and stasis in transgenic sickle mice: utility of a dorsal skin fold chamber for intravital microscopy. American Journal of Hematology. 77: 117-25. PMID 15389823 DOI: 10.1002/Ajh.20143 |
0.399 |
|
| 2004 |
Shen YH, Utama B, Wang J, Raveendran M, Senthil D, Waldman WJ, Belcher JD, Vercellotti G, Martin D, Mitchelle BM, Wang XL. Human cytomegalovirus causes endothelial injury through the ataxia telangiectasia mutant and p53 DNA damage signaling pathways. Circulation Research. 94: 1310-7. PMID 15105295 DOI: 10.1161/01.Res.0000129180.13992.43 |
0.336 |
|
| 2004 |
Kaul DK, Liu XD, Choong S, Belcher JD, Vercellotti GM, Hebbel RP. Anti-inflammatory therapy ameliorates leukocyte adhesion and microvascular flow abnormalities in transgenic sickle mice. American Journal of Physiology. Heart and Circulatory Physiology. 287: H293-301. PMID 15001449 DOI: 10.1152/Ajpheart.01150.2003 |
0.446 |
|
| 2004 |
Mahaseth H, Belcher JD, Welch TE, Sonbol KM, Bowlin PR, Hebbel RP, Ma L, Hsia CJ, Vercellotti GM. Polynitroxyl Albumin Prevents Vaso-Occlusion in Transgenic Sickle Mice. Blood. 104: 366-366. DOI: 10.1182/Blood.V104.11.366.366 |
0.465 |
|
| 2004 |
Belcher JD, Welch TE, Mahaseth H, Sonbol KM, Bowlin PR, Bischof JC, Hebbel RP, Vercellotti GM. Heme Oxygenase-1: A Potential Modulator of Inflammation and Vaso-Occlusion in Sickle Cell Disease. Blood. 104: 365-365. DOI: 10.1182/Blood.V104.11.365.365 |
0.48 |
|
| 2003 |
Balla J, Vercellotti GM, Nath K, Yachie A, Nagy E, Eaton JW, Balla G. Haem, haem oxygenase and ferritin in vascular endothelial cell injury. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 18: v8-12. PMID 12817058 DOI: 10.1093/Ndt/Gfg1034 |
0.391 |
|
| 2003 |
Belcher JD, Bryant CJ, Nguyen J, Bowlin PR, Kielbik MC, Bischof JC, Hebbel RP, Vercellotti GM. Transgenic sickle mice have vascular inflammation. Blood. 101: 3953-9. PMID 12543857 DOI: 10.1182/Blood-2002-10-3313 |
0.429 |
|
| 2003 |
Vercellotti GM. PlGF: a link between inflammation and angiogenesis in sickle disease Blood. 102: 1153-1153. DOI: 10.1182/Blood-2003-06-1860 |
0.394 |
|
| 2002 |
Jeney V, Balla J, Yachie A, Varga Z, Vercellotti GM, Eaton JW, Balla G. Pro-oxidant and cytotoxic effects of circulating heme. Blood. 100: 879-87. PMID 12130498 DOI: 10.1182/Blood.V100.3.879 |
0.362 |
|
| 2001 |
Vercellotti GM. Overview of infections and cardiovascular diseases Journal of Allergy and Clinical Immunology. 108: S117-S120. PMID 11586278 DOI: 10.1067/Mai.2001.117976 |
0.322 |
|
| 2001 |
Sato K, Balla J, Otterbein L, Smith RN, Brouard S, Lin Y, Csizmadia E, Sevigny J, Robson SC, Vercellotti G, Choi AM, Bach FH, Soares MP. Carbon monoxide generated by heme oxygenase-1 suppresses the rejection of mouse-to-rat cardiac transplants Journal of Immunology. 166: 4185-4194. PMID 11238670 DOI: 10.4049/Jimmunol.166.6.4185 |
0.348 |
|
| 2001 |
Nath KA, Vercellotti GM, Grande JP, Miyoshi H, Paya CV, Manivel JC, Haggard JJ, Croatt AJ, Payne WD, Alam J. Heme protein-induced chronic renal inflammation: Suppressive effect of induced heme oxygenase-1 Kidney International. 59: 106-117. PMID 11135063 DOI: 10.1046/J.1523-1755.2001.00471.X |
0.411 |
|
| 2000 |
Wang J, Marker PH, Belcher JD, Wilcken DEL, Burns LJ, Vercellotti GM, Wang XL. Human cytomegalovirus immediate early proteins upregulate endothelial p53 function Febs Letters. 474: 213-216. PMID 10838087 DOI: 10.1016/S0014-5793(00)01604-5 |
0.334 |
|
| 2000 |
Bratt J, Belcher J, Vercellotti GM, Palmblad J. Effects of anti-rheumatic gold salts on NF-κB mobilization and tumour necrosis factor-alpha (TNF-α)-induced neutrophil-dependent cytotoxicity for human endothelial cells Clinical and Experimental Immunology. 120: 79-84. PMID 10759767 DOI: 10.1046/J.1365-2249.2000.01190.X |
0.334 |
|
| 2000 |
Belcher JD, Marker PH, Weber JP, Hebbel RP, Vercellotti GM. Activated monocytes in sickle cell disease: potential role in the activation of vascular endothelium and vaso-occlusion Blood. 96: 2451-2459. DOI: 10.1182/Blood.V96.7.2451.H8002451_2451_2459 |
0.409 |
|
| 2000 |
Osarogiagbon UR, Choong S, Belcher JD, Vercellotti GM, Paller MS, Hebbel RP. Reperfusion injury pathophysiology in sickle transgenic mice Blood. 96: 314-320. DOI: 10.1182/Blood.V96.1.314 |
0.387 |
|
| 2000 |
Balla J, Balla G, Jeney V, Kakuk G, Jacob HS, Vercellotti GM. Ferriporphyrins and endothelium: a 2-edged sword—promotion of oxidation and induction of cytoprotectants Blood. 95: 3442-3450. DOI: 10.1182/Blood.V95.11.3442.011K51_3442_3450 |
0.4 |
|
| 1999 |
Belcher JD, Marker PH, Geiger P, Girotti AW, Steinberg MH, Hebbel RP, Vercellotti GM. Low-density lipoprotein susceptibility to oxidation and cytotoxicity to endothelium in sickle cell anemia Journal of Laboratory and Clinical Medicine. 133: 605-612. PMID 10360636 DOI: 10.1016/S0022-2143(99)90191-9 |
0.345 |
|
| 1999 |
Burns LJ, Pooley JC, Walsh DJ, Vercellotti GM, Weber ML, Kovacs A. Intercellular adhesion molecule-1 expression in endothelial cells is activated by cytomegalovirus immediate early proteins Transplantation. 67: 137-144. PMID 9921810 DOI: 10.1097/00007890-199901150-00023 |
0.341 |
|
| 1998 |
Juckett M, Zheng Y, Yuan H, Pastor T, Antholine W, Weber M, Vercellotti G. Heme and the endothelium. Effects of nitric oxide on catalytic iron and heme degradation by heme oxygenase. The Journal of Biological Chemistry. 273: 23388-97. PMID 9722574 DOI: 10.1074/Jbc.273.36.23388 |
0.355 |
|
| 1997 |
Matthews AJ, Vercellotti GM, Menchaca HJ, Bloch PHS, Michalek VN, Marker PH, Murar J, Buchwald H. Iron and atherosclerosis: Inhibition by the iron chelator deferiprone (L1)1 Journal of Surgical Research. 73: 35-40. PMID 9441790 DOI: 10.1006/Jsre.1997.5180 |
0.313 |
|
| 1996 |
Juckett MB, Weber M, Balla J, Jacob HS, Vercellotti GM. Nitric oxide donors modulate ferritin and protect endothelium from oxidative injury Free Radical Biology and Medicine. 20: 63-73. PMID 8903680 DOI: 10.1016/0891-5849(95)02024-1 |
0.345 |
|
| 1996 |
Agarwal A, Balla J, Balla G, Croatt AJ, Vercellotti GM, Nath KA. Renal tubular epithelial cells mimic endothelial cells upon exposure to oxidized LDL American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 271: F814-F823. PMID 8898011 DOI: 10.1152/Ajprenal.1996.271.4.F814 |
0.381 |
|
| 1995 |
Balla J, Nath KA, Balla G, Juckett MB, Jacob HS, Vercellotti GM. Endothelial cell heme oxygenase and ferritin induction in rat lung by hemoglobin in vivo American Journal of Physiology - Lung Cellular and Molecular Physiology. 268: L321-L327. PMID 7864152 DOI: 10.1152/Ajplung.1995.268.2.L321 |
0.337 |
|
| 1995 |
Nath KA, Balla J, Croatt AJ, Vercellotti GM. Heme protein-mediated renal injury: A protective role for 21-aminosteroids in vitro and in vivo Kidney International. 47: 592-602. PMID 7723246 DOI: 10.1038/Ki.1995.75 |
0.319 |
|
| 1994 |
Vercellotti GM, Balla G, Balla J, Nath K, Eaton JW, Jacob HS. Heme and the vasculature: An oxidative hazard that induces antioxidant defenses in the endothelium Artificial Cells, Blood Substitutes, and Biotechnology. 22: 207-213. PMID 8087243 DOI: 10.3109/10731199409117415 |
0.353 |
|
| 1993 |
Balla J, Jacob HS, Balla G, Nath K, Eaton JW, Vercellotti GM. Endothelial-cell heme uptake from heme proteins: Induction of sensitization and desensitization to oxidant damage Proceedings of the National Academy of Sciences of the United States of America. 90: 9285-9289. PMID 8415693 DOI: 10.1073/Pnas.90.20.9285 |
0.395 |
|
| 1993 |
Slungaard A, Vercellotti GM, Tran T, Gleich GJ, Key NS. Eosinophil cationic granule proteins impair thrombomodulin function: A potential mechanism for thromboembolism in hypereosinophilic heart disease Journal of Clinical Investigation. 91: 1721-1730. PMID 8386194 DOI: 10.1172/Jci116382 |
0.309 |
|
| 1993 |
Belcher JD, Balla J, Balla G, Jacobs DR, Gross M, Jacob HS, Vercellotti GM. Vitamin E, LDL, and endothelium: Brief oral vitamin supplementation prevents oxidized LDL-mediated vascular injury in vitro Arteriosclerosis, Thrombosis, and Vascular Biology. 13: 1779-1789. PMID 8241098 DOI: 10.1161/01.Atv.13.12.1779 |
0.318 |
|
| 1993 |
Cermak J, Key N, Bach R, Balla J, Jacob H, Vercellotti G. C-reactive protein induces human peripheral blood monocytes to synthesize tissue factor Blood. 82: 513-520. DOI: 10.1182/Blood.V82.2.513.513 |
0.36 |
|
| 1993 |
Bok RA, Jacob HS, Balla J, Juckett M, Stelle T, Shatos MA, Vercellotti GM. Herpes Simplex Virus Decreases Endothelial Cell Plasminogen Activator Inhibitor Thrombosis and Haemostasis. 69: 253-258. DOI: 10.1055/S-0038-1651590 |
0.317 |
|
| 1993 |
Eaton J, Balla G, Balla J, Vercellotti G. Heme iron and oxidative cell death Free Radical Biology and Medicine. 15: 516. DOI: 10.1016/0891-5849(93)90354-W |
0.313 |
|
| 1992 |
Nath KA, Balla G, Vercellotti GM, Balla J, Jacob HS, Levin MD, Rosenberg ME. Induction of heme oxygenase is a rapid, protective response in rhabdomyolysis in the rat Journal of Clinical Investigation. 90: 267-270. PMID 1634613 DOI: 10.1172/Jci115847 |
0.321 |
|
| 1992 |
Key NS, Platt JL, Vercellotti GM. Vascular endothelial cell proteoglycans are susceptible to cleavage by neutrophils Arteriosclerosis, Thrombosis, and Vascular Biology. 12: 836-842. PMID 1616909 DOI: 10.1161/01.Atv.12.7.836 |
0.396 |
|
| 1992 |
Antonov AS, Key NS, Smirnov MD, Jacob HS, Vercellotti GM, Smirnov VN. Prothrombotic phenotype diversity of human aortic endothelial cells in culture Thrombosis Research. 67: 135-145. PMID 1332214 DOI: 10.1016/0049-3848(92)90133-U |
0.335 |
|
| 1992 |
Stroncek D, Vercellotti G, Hammerschmidt D, Christie D, Shankar R, Jacob H. Characterization of multiple quinine-dependent antibodies in a patient with episodic hemolytic uremic syndrome and immune agranulocytosis Blood. 80: 241-248. DOI: 10.1182/Blood.V80.1.241.Bloodjournal801241 |
0.304 |
|
| 1991 |
Balla G, Jacob HS, Eaton JW, Belcher JD, Vercellotti GM. Hemin: A possible physiological mediator of low density lipoprotein oxidation and endothelial injury Arteriosclerosis, Thrombosis, and Vascular Biology. 11: 1700-1711. PMID 1931871 DOI: 10.1161/01.Atv.11.6.1700 |
0.322 |
|
| 1991 |
Dalmasso AP, Vercellotti GM, Platt JL, Bach FH. Inhibition of complement-mediated endothelial cell cytotoxicity by decay-accelerating factor: Potential for prevention of xenograft hyperacute rejection Transplantation. 52: 530-533. PMID 1716798 DOI: 10.1097/00007890-199109000-00029 |
0.357 |
|
| 1991 |
Lee PK, Vercellotti GM, Deringer JR, Schlievert PM. Effects of staphylococcal toxic shock syndrome toxin 1 on aortic endothelial cells Journal of Infectious Diseases. 164: 711-719. PMID 1654356 DOI: 10.1093/Infdis/164.4.711 |
0.31 |
|
| 1990 |
Key NS, Vercellotti GM, Winkelmann JC, Moldow CF, Goodman JL, Esmon NL, Esmon CT, Jacob HS. Infection of vascular endothelial cells with herpes simplex virus enhances tissue factor activity and reduces thrombomodulin expression. Proceedings of the National Academy of Sciences of the United States of America. 87: 7095-9. PMID 2169619 DOI: 10.1073/Pnas.87.18.7095 |
0.309 |
|
| 1990 |
Confer DL, Vercellotti GM, Kotasek D, Goodman JL, Ochoa A, Jacob HS. Herpes simplex virus-infected cells disarm killer lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 87: 3609-13. PMID 2159156 DOI: 10.1073/Pnas.87.9.3609 |
0.303 |
|
| 1990 |
Platt JL, Vercellotti GM, Lindman BJ, Oegema TR, Bach FH, Dalmasso AP. Release of heparan sulfate from endothelial cells - Implications for pathogenesis of hyperacute rejection Journal of Experimental Medicine. 171: 1363-1368. PMID 2139104 DOI: 10.1084/Jem.171.4.1363 |
0.386 |
|
| 1990 |
Slungaard A, Vercellotti GM, Walker G, Nelson RD, Jacob HS. Tumor necrosis factor α/cachectin stimulates eosinophil oxidant production and toxicity towards human endothelium Journal of Experimental Medicine. 171: 2025-2041. PMID 1972179 DOI: 10.1084/Jem.171.6.2025 |
0.373 |
|
| 1989 |
Vercellotti GM, Wickham NWR, Gustafson KS, Yin HQ, Hebert M, Jacob HS. Thrombin-treated endothelium primes neutrophil functions: Inhibition by platelet-activating factor receptor antagonists Journal of Leukocyte Biology. 45: 483-490. PMID 2542422 DOI: 10.1002/Jlb.45.6.483 |
0.369 |
|
| 1988 |
Farber NE, Vercellotti GM, Jacob HS, Pieper GM, Gross GJ. Evidence for a role of iron-catalyzed oxidants in functional and metabolic stunning in the canine heart Circulation Research. 63: 351-360. PMID 3396156 DOI: 10.1161/01.Res.63.2.351 |
0.311 |
|
| 1988 |
Vercellotti GM, Dobson M, Schorer AE, Moldow CF. Endothelial Cell Heterogeneity: Antioxidant Profiles Determine Vulnerability to Oxidant Injury Proceedings of the Society For Experimental Biology and Medicine. 187: 181-189. PMID 3340627 DOI: 10.3181/00379727-187-42652 |
0.361 |
|
| 1988 |
Visser MR, Tracy PB, Vercellotti GM, Goodman JL, White JG, Jacob HS. Enhanced thrombin generation and platelet binding on herpes simplex virus-infected endothelium. Proceedings of the National Academy of Sciences of the United States of America. 85: 8227-30. PMID 2847155 DOI: 10.1073/Pnas.85.21.8227 |
0.32 |
|
| 1988 |
Vercellotti G, Yin H, Gustafson K, Nelson R, Jacob H. Platelet-activating factor primes neutrophil responses to agonists: role in promoting neutrophil-mediated endothelial damage Blood. 71: 1100-1107. DOI: 10.1182/Blood.V71.4.1100.Bloodjournal7141100 |
0.358 |
|
| 1987 |
Smith CM, Hebbel RP, Tukey DP, Clawson CC, White JG, Vercellotti GM. Pluronic F-68 reduces the endothelial adherence and improves the rheology of liganded sickle erythrocytes. Blood. 69: 1631-1636. DOI: 10.1182/Blood.V69.6.1631.1631 |
0.351 |
|
| 1987 |
Jacob H, Wickham N, Vercellotti G. PAF as a facilitator of the immune response: Its role in priming inflammatory and endothelial cells Prostaglandins. 34: 171. DOI: 10.1016/0090-6980(87)90214-0 |
0.319 |
|
| 1986 |
Stroncek DF, Vercellotti GM, Pil Won Huh, Jacob HS. Neutrophil oxidants inactivate alpha-1-protease inhibitor and promote PMN-mediated detachment of cultured endothelium. Protection by free methionine Arteriosclerosis. 6: 332-340. PMID 3486653 DOI: 10.1161/01.Atv.6.3.332 |
0.376 |
|
| 1985 |
Vercellotti GM, Van Asbeck BS, Jacob HS. Oxygen radical-induced erythrocyte hemolysis by neutrophils. Critical role of iron and lactoferrin Journal of Clinical Investigation. 76: 956-962. PMID 2995452 DOI: 10.1172/Jci112095 |
0.32 |
|
| 1985 |
Van Asbeck BS, Hoidal J, Vercellotti GM, Schwartz BA, Moldow CF, Jacob HS. Protection against lethal hyperoxia by tracheal insufflation of erythrocytes: Role of red cell glutathione Science. 227: 756-759. PMID 2982213 DOI: 10.1126/Science.2982213 |
0.334 |
|
| 1985 |
Perri RT, Vercellotti G, McCarthy J, Vessella RL, Furcht LT. Laminin selectively enhances monocyte-macrophage-mediated tumoricidal activity. Journal of Laboratory and Clinical Medicine. 105: 30-35. DOI: 10.5555/Uri:Pii:002221438590085X |
0.313 |
|
| 1984 |
Ascensao JL, Vercellotti GM, Jacob HS, Zanjani ED. Role of endothelial cells in human hematopoiesis: Modulation of mixed colony growth in vitro Blood. 63: 553-558. PMID 6607755 DOI: 10.1182/Blood.V63.3.553.553 |
0.345 |
|
| 1983 |
Vercellotti G, McCarthy J, Furcht L, Jacob H, Moldow C. Inflamed fibronectin: an altered fibronectin enhances neutrophil adhesion Blood. 62: 1063-1069. DOI: 10.1182/Blood.V62.5.1063.Bloodjournal6251063 |
0.378 |
|
| 1982 |
Jacob HS, Moldow CF, Flynn PJ, Weisdorf DJ, Vercellotti GM, Hammerschmidt DE. Therapeutic ramifications of the interaction of complement, granulocytes, and platelets in the production of acute lung injury. Annals of the New York Academy of Sciences. 384: 489-95. PMID 6953835 DOI: 10.1111/J.1749-6632.1982.Tb21395.X |
0.34 |
|
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