| Year |
Citation |
Score |
| 2023 |
Nickle RA, DeOca KB, Garcia BL, Mannie MD. Soluble CD25 imposes a low-zone IL-2 signaling environment that favors competitive outgrowth of antigen-experienced CD25 regulatory and memory T cells. Cellular Immunology. 384: 104664. PMID 36642016 DOI: 10.1016/j.cellimm.2023.104664 |
0.31 |
|
| 2021 |
Islam SMT, Won J, Khan M, Mannie MD, Singh I. Hypoxia-inducible factor-1 drives divergent immunomodulatory functions in the pathogenesis of autoimmune diseases. Immunology. PMID 33813735 DOI: 10.1111/imm.13335 |
0.331 |
|
| 2020 |
DeOca KB, Moorman CD, Garcia BL, Mannie MD. Low-Zone IL-2 Signaling: Fusion Proteins Containing Linked CD25 and IL-2 Domains Sustain Tolerogenic Vaccination and Promote Dominance of FOXP3 Tregs . Frontiers in Immunology. 11: 541619. PMID 33072087 DOI: 10.3389/fimmu.2020.541619 |
0.342 |
|
| 2020 |
Mannie MD, DeOca KB, Bastian AG, Moorman CD. Tolerogenic vaccines: Targeting the antigenic and cytokine niches of FOXP3 regulatory T cells. Cellular Immunology. 355: 104173. PMID 32712270 DOI: 10.1016/J.Cellimm.2020.104173 |
0.529 |
|
| 2020 |
Moorman CD, Bastian AG, DeOca KB, Mannie MD. A GM-CSF-neuroantigen tolerogenic vaccine elicits inefficient antigen recognition events below the CD40L triggering threshold to expand CD4 CD25 FOXP3 Tregs that inhibit experimental autoimmune encephalomyelitis (EAE). Journal of Neuroinflammation. 17: 180. PMID 32522287 DOI: 10.1186/S12974-020-01856-8 |
0.504 |
|
| 2018 |
Moorman CD, Curtis AD, Bastian AG, Elliott SE, Mannie MD. A GMCSF-Neuroantigen Tolerogenic Vaccine Elicits Systemic Lymphocytosis of CD4 CD25 FOXP3 Regulatory T Cells in Myelin-Specific TCR Transgenic Mice Contingent Upon Low-Efficiency T Cell Antigen Receptor Recognition. Frontiers in Immunology. 9: 3119. PMID 30687323 DOI: 10.3389/Fimmu.2018.03119 |
0.522 |
|
| 2017 |
Wilkinson DS, Ghosh D, Nickle RA, Moorman CD, Mannie MD. Partial CD25 Antagonism Enables Dominance of Antigen-Inducible CD25high FOXP3+ Regulatory T Cells As a Basis for a Regulatory T Cell-Based Adoptive Immunotherapy. Frontiers in Immunology. 8: 1782. PMID 29312311 DOI: 10.3389/Fimmu.2017.01782 |
0.511 |
|
| 2016 |
Wang D, Ghosh D, Islam SM, Moorman CD, Thomason AE, Wilkinson DS, Mannie MD. IFN-β Facilitates Neuroantigen-Dependent Induction of CD25+ FOXP3+ Regulatory T Cells That Suppress Experimental Autoimmune Encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). PMID 27619998 DOI: 10.4049/Jimmunol.1500411 |
0.426 |
|
| 2016 |
Ghosh D, Curtis AD, Wilkinson DS, Mannie MD. Depletion of CD4+ CD25+ regulatory T cells confers susceptibility to experimental autoimmune encephalomyelitis (EAE) in GM-CSF-deficient Csf2-/- mice. Journal of Leukocyte Biology. PMID 27256565 DOI: 10.1189/Jlb.3A0815-359R |
0.453 |
|
| 2016 |
Patial S, Curtis AD, Lai WS, Stumpo DJ, Hill GD, Flake GP, Mannie MD, Blackshear PJ. Enhanced stability of tristetraprolin mRNA protects mice against immune-mediated inflammatory pathologies. Proceedings of the National Academy of Sciences of the United States of America. 113: 1865-70. PMID 26831084 DOI: 10.1073/Pnas.1519906113 |
0.331 |
|
| 2014 |
Curtis AD, Taslim N, Reece SP, Grebenciucova E, Ray RH, Rosenbaum MD, Wardle RL, Van Scott MR, Mannie MD. The extracellular domain of myelin oligodendrocyte glycoprotein elicits atypical experimental autoimmune encephalomyelitis in rat and Macaque species. Plos One. 9: e110048. PMID 25303101 DOI: 10.1371/Journal.Pone.0110048 |
0.415 |
|
| 2014 |
Islam SM, Curtis AD, Taslim N, Wilkinson DS, Mannie MD. GM-CSF-neuroantigen fusion proteins reverse experimental autoimmune encephalomyelitis and mediate tolerogenic activity in adjuvant-primed environments: association with inflammation-dependent, inhibitory antigen presentation. Journal of Immunology (Baltimore, Md. : 1950). 193: 2317-29. PMID 25049359 DOI: 10.4049/Jimmunol.1303223 |
0.53 |
|
| 2013 |
Mannie MD, Curtis AD. Tolerogenic vaccines for Multiple sclerosis. Human Vaccines & Immunotherapeutics. 9: 1032-8. PMID 23357858 DOI: 10.4161/Hv.23685 |
0.432 |
|
| 2012 |
Mannie MD, Blanchfield JL, Islam SM, Abbott DJ. Cytokine-neuroantigen fusion proteins as a new class of tolerogenic, therapeutic vaccines for treatment of inflammatory demyelinating disease in rodent models of multiple sclerosis. Frontiers in Immunology. 3: 255. PMID 22934095 DOI: 10.3389/Fimmu.2012.00255 |
0.752 |
|
| 2011 |
Abbott DJ, Blanchfield JL, Martinson DA, Russell SC, Taslim N, Curtis AD, Mannie MD. Neuroantigen-specific, tolerogenic vaccines: GM-CSF is a fusion partner that facilitates tolerance rather than immunity to dominant self-epitopes of myelin in murine models of experimental autoimmune encephalomyelitis (EAE). Bmc Immunology. 12: 72. PMID 22208499 DOI: 10.1186/1471-2172-12-72 |
0.735 |
|
| 2010 |
Blanchfield JL, Mannie MD. A GMCSF-neuroantigen fusion protein is a potent tolerogen in experimental autoimmune encephalomyelitis (EAE) that is associated with efficient targeting of neuroantigen to APC. Journal of Leukocyte Biology. 87: 509-21. PMID 20007248 DOI: 10.1189/Jlb.0709520 |
0.759 |
|
| 2009 |
Rehm KE, Connor RF, Jones GJ, Yimbu K, Mannie MD, Roper RL. Vaccinia virus decreases major histocompatibility complex (MHC) class II antigen presentation, T-cell priming, and peptide association with MHC class II. Immunology. 128: 381-92. PMID 20067538 DOI: 10.1111/J.1365-2567.2009.03120.X |
0.481 |
|
| 2009 |
Mannie MD, Abbott DJ, Blanchfield JL. Experimental autoimmune encephalomyelitis in Lewis rats: IFN-beta acts as a tolerogenic adjuvant for induction of neuroantigen-dependent tolerance. Journal of Immunology (Baltimore, Md. : 1950). 182: 5331-41. PMID 19380780 DOI: 10.4049/Jimmunol.0803756 |
0.718 |
|
| 2009 |
Mannie M, Swanborg RH, Stepaniak JA. Experimental autoimmune encephalomyelitis in the rat. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 15.2. PMID 19347844 DOI: 10.1002/0471142735.Im1502S19 |
0.371 |
|
| 2007 |
Mannie MD, Abbott DJ. A fusion protein consisting of IL-16 and the encephalitogenic peptide of myelin basic protein constitutes an antigen-specific tolerogenic vaccine that inhibits experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 179: 1458-65. PMID 17641011 DOI: 10.4049/Jimmunol.179.3.1458 |
0.527 |
|
| 2007 |
Mannie MD, Clayson BA, Buskirk EJ, DeVine JL, Hernandez JJ, Abbott DJ. IL-2/neuroantigen fusion proteins as antigen-specific tolerogens in experimental autoimmune encephalomyelitis (EAE): correlation of T cell-mediated antigen presentation and tolerance induction. Journal of Immunology (Baltimore, Md. : 1950). 178: 2835-43. PMID 17312127 DOI: 10.4049/Jimmunol.178.5.2835 |
0.549 |
|
| 2007 |
Mannie MD, Devine JL, Clayson BA, Lewis LT, Abbott DJ. Cytokine-neuroantigen fusion proteins: new tools for modulation of myelin basic protein (MBP)-specific T cell responses in experimental autoimmune encephalomyelitis. Journal of Immunological Methods. 319: 118-32. PMID 17188704 DOI: 10.1016/J.Jim.2006.11.005 |
0.534 |
|
| 2005 |
Mannie MD, McConnell TJ, Xie C, Li YQ. Activation-dependent phases of T cells distinguished by use of optical tweezers and near infrared Raman spectroscopy. Journal of Immunological Methods. 297: 53-60. PMID 15777930 DOI: 10.1016/J.Jim.2004.11.020 |
0.423 |
|
| 2004 |
Mannie MD, Dawkins JG, Walker MR, Clayson BA, Patel DM. MHC class II biosynthesis by activated rat CD4+ T cells: development of repression in vitro and modulation by APC-derived signals. Cellular Immunology. 230: 33-43. PMID 15541717 DOI: 10.1016/J.Cellimm.2004.08.005 |
0.731 |
|
| 2003 |
Mannie MD, Fraser DJ, McConnell TJ. IL-4 responsive CD4+ T cells specific for myelin basic protein: IL-2 confers a prolonged postactivation refractory phase. Immunology and Cell Biology. 81: 8-19. PMID 12534941 DOI: 10.1046/J.1440-1711.2003.01131.X |
0.432 |
|
| 2002 |
Walker MR, Mannie MD. Acquisition of functional MHC class II/peptide complexes by T cells during thymic development and CNS-directed pathogenesis. Cellular Immunology. 218: 13-25. PMID 12470610 DOI: 10.1016/S0008-8749(02)00577-4 |
0.703 |
|
| 2001 |
Patel DM, Mannie MD. Intercellular exchange of class II major histocompatibility complex/peptide complexes is a conserved process that requires activation of T cells but is constitutive in other types of antigen presenting cell. Cellular Immunology. 214: 165-72. PMID 12088415 DOI: 10.1006/Cimm.2001.1897 |
0.653 |
|
| 2001 |
Patel DM, Dudek RW, Mannie MD. Intercellular exchange of class II MHC complexes: ultrastructural localization and functional presentation of adsorbed I-A/peptide complexes. Cellular Immunology. 214: 21-34. PMID 11902826 DOI: 10.1006/Cimm.2002.1887 |
0.65 |
|
| 2001 |
Mannie MD, Norris MS. MHC class-II-restricted antigen presentation by myelin basic protein-specific CD4+ T cells causes prolonged desensitization and outgrowth of CD4- responders. Cellular Immunology. 212: 51-62. PMID 11716529 DOI: 10.1006/Cimm.2001.1843 |
0.553 |
|
| 2001 |
Norris MS, McConnell TJ, Mannie MD. Interleukin-2 promotes antigenic reactivity of rested T cells but prolongs the postactivational refractory phase of activated T cells. Cellular Immunology. 211: 51-60. PMID 11585388 DOI: 10.1006/Cimm.2001.1821 |
0.495 |
|
| 2001 |
Mannie MD, Walker MR. Feedback activation of T-cell antigen-presenting cells during interactions with T-cell responders. Journal of Leukocyte Biology. 70: 252-60. PMID 11493617 DOI: 10.1189/Jlb.70.2.252 |
0.694 |
|
| 2001 |
Walker MR, Mannie MD. T cell recognition of rat myelin basic protein as a TCR antagonist inhibits reciprocal activation of antigen-presenting cells and engenders resistance to experimental autoimmune encephalomyelitis. European Journal of Immunology. 31: 1894-9. PMID 11433386 DOI: 10.1002/1521-4141(200106)31:6<1894::Aid-Immu1894>3.0.Co;2-N |
0.715 |
|
| 2001 |
Mannie MD. T cell-mediated antigen presentation: a potential mechanism of infectious tolerance. Immunologic Research. 23: 1-21. PMID 11417857 DOI: 10.1385/Ir:23:1:01 |
0.536 |
|
| 1999 |
Patel DM, Arnold PY, White GA, Nardella JP, Mannie MD. Class II MHC/peptide complexes are released from APC and are acquired by T cell responders during specific antigen recognition. Journal of Immunology (Baltimore, Md. : 1950). 163: 5201-10. PMID 10553040 |
0.624 |
|
| 1999 |
Walker MR, White GA, Nardella JP, Mannie MD. An autologous self-antigen differentially regulates expression of I-A glycoproteins and B7 costimulatory molecules on CD4- CD8- T helper cells. Journal of Leukocyte Biology. 66: 120-6. PMID 10410999 DOI: 10.1002/Jlb.66.1.120 |
0.736 |
|
| 1999 |
Mannie MD. Immunological self/nonself discrimination: integration of self vs nonself during cognate T cell interactions with antigen-presenting cells. Immunologic Research. 19: 65-87. PMID 10374696 DOI: 10.1007/Bf02786477 |
0.482 |
|
| 1999 |
Arnold PY, Mannie MD. Vesicles bearing MHC class II molecules mediate transfer of antigen from antigen-presenting cells to CD4+ T cells. European Journal of Immunology. 29: 1363-73. PMID 10229104 DOI: 10.1002/(Sici)1521-4141(199904)29:04<1363::Aid-Immu1363>3.0.Co;2-0 |
0.495 |
|
| 1998 |
Arnold PY, Kearse KP, Marinakis CA, Mannie MD. A novel monoclonal antibody against rat LFA-1: blockade of LFA-1 and CD4 augments class II MHC expression on T cells. Hybridoma. 17: 331-8. PMID 9790067 DOI: 10.1089/Hyb.1998.17.331 |
0.518 |
|
| 1998 |
Mannie MD, Nardella JP, White GA, Arnold PY, Davidian DK. Class II MHC/peptide complexes on T cell antigen-presenting cells: agonistic antigen recognition inhibits subsequent antigen presentation. Cellular Immunology. 186: 111-20. PMID 9665753 DOI: 10.1006/Cimm.1998.1301 |
0.532 |
|
| 1998 |
Mannie MD, White GA, Nardella JP, Davidian DK, Arnold PY. Partial agonism elicits an enduring phase of T-cell-medicated antigen presentation. Cellular Immunology. 186: 83-93. PMID 9665750 DOI: 10.1006/Cimm.1998.1299 |
0.526 |
|
| 1998 |
Arnold PY, Davidian DK, Mannie MD. Antigen presentation by T cells: T cell receptor ligation promotes antigen acquisition from professional antigen-presenting cells. European Journal of Immunology. 27: 3198-205. PMID 9464806 DOI: 10.1002/Eji.1830271217 |
0.512 |
|
| 1997 |
Judge SIV, Yeh JZ, Mannie MD, Seifert LP, Paterson PY. Potassium Channel Blockers Inhibit Adoptive Transfer of Experimental Allergic Encephalomyelitis by Myelin-Basic-Protein-Stimulated Rat T Lymphocytes. Journal of Biomedical Science. 4: 169-178. PMID 11725150 DOI: 10.1007/Bf02255646 |
0.424 |
|
| 1997 |
Judge SIV, Paterson PY, Mannie MD, Yeh JZ. Modulation of Outward K(+) Conductance Is a Post-Activational Event in Rat T Lymphocytes Responsible for the Adoptive Transfer of Experimental Allergic Encephalomyelitis. Journal of Biomedical Science. 4: 98-110. PMID 11725140 DOI: 10.1007/Bf02255600 |
0.455 |
|
| 1997 |
Johnson BD, Nardella JP, McConnell TJ, Mannie MD. Acquired resistance to experimental autoimmune encephalomyelitis is independent of Vβ usage Cellular Immunology. 179: 55-65. PMID 9259772 DOI: 10.1006/Cimm.1997.1143 |
0.503 |
|
| 1997 |
Mannie MD. The post-activation refractory phase: a mechanism to measure antigenic complexity and ensure self-tolerance among mature peripheral T lymphocytes. Medical Hypotheses. 47: 467-70. PMID 8961244 DOI: 10.1016/S0306-9877(96)90159-0 |
0.543 |
|
| 1996 |
Mannie MD, White GA, Lake KR, Nardella JP, Marinakis CA, McConnell TJ. T-helper lymphocytes specific for myelin basic protein: low-density activation prolongs a postactivation refractory phase marked by decreased pathogenicity and enhanced sensitivity to anergy. Cellular Immunology. 172: 108-17. PMID 8806813 DOI: 10.1006/Cimm.1996.0221 |
0.55 |
|
| 1995 |
Mannie MD, Prevost KD, Marinakis CA. Prostaglandin E2 promotes the induction of anergy during T helper cell recognition of myelin basic protein. Cellular Immunology. 160: 132-8. PMID 7531117 DOI: 10.1016/0008-8749(95)80018-E |
0.552 |
|
| 1994 |
Mannie MD, Truman H, Morrison-Plummer J. T-helper lymphocytes specific for myelin basic protein: activation-induced refractoriness of IL-2 production pathways augments an anti-CD4-mediated proliferative deficit. Cellular Immunology. 154: 484-97. PMID 7510586 DOI: 10.1006/Cimm.1994.1093 |
0.52 |
|
| 1994 |
Mannie MD, Watkins SL. Emergence of a radioresistant population of co-stimulatory splenocytes during remission of experimental autoimmune encephalomyelitis in Lewis rats. Immunology Letters. 38: 237-42. PMID 7510267 DOI: 10.1016/0165-2478(93)90012-Q |
0.553 |
|
| 1994 |
Mannie MD, Morrison-Plummer J, Torres-Garcia B, Hannaway C, Jones C, Smith AM. Parallel costimulatory pathways promote myelin basic protein-stimulated proliferation of encephalitogenic rat T cells. Cellular Immunology. 153: 312-28. PMID 7509724 DOI: 10.1006/Cimm.1994.1031 |
0.552 |
|
| 1994 |
Sandstrom PA, Mannie MD, Butke TM. Inhibition of activation-induced death in T cell hybridomas by thiol antioxidants: Oxidative stress as a mediator of apoptosis Journal of Leukocyte Biology. 55: 221-226. PMID 7507967 DOI: 10.1002/Jlb.55.2.221 |
0.432 |
|
| 1993 |
Mannie MD. Immune discrimination of self and nonself: a unified theory for the induction of self tolerance among thymocytes and mature peripheral T cells. Medical Hypotheses. 40: 105-12. PMID 8455473 DOI: 10.1016/0306-9877(93)90138-G |
0.49 |
|
| 1993 |
Watkins SL, Mannie MD. A unique costimulatory pathway defined with T cell hybridomas specific for myelin basic protein: third party costimulators restrict antigenic responses in time and space. Cellular Immunology. 147: 25-40. PMID 7681731 DOI: 10.1006/Cimm.1993.1045 |
0.537 |
|
| 1992 |
Deane KH, Mannie MD. An alternative pathway of B cell activation: stilbene disulfonates interact with a Cl- binding motif on AEn-related proteins to stimulate mitogenesis. European Journal of Immunology. 22: 1165-71. PMID 1577060 DOI: 10.1002/Eji.1830220509 |
0.402 |
|
| 1992 |
Mannie MD, Nairn R. Subset-specific co-stimulatory signals are required for IL-2 production but not growth inhibition responses by T cell hybrids specific for myelin basic protein. Cellular Immunology. 140: 219-36. PMID 1371244 DOI: 10.1016/0008-8749(92)90189-V |
0.521 |
|
| 1991 |
Mannie MD. A unified model for T cell antigen recognition and thymic selection of the T cell repertoire. Journal of Theoretical Biology. 151: 169-92. PMID 1943141 DOI: 10.1016/S0022-5193(05)80360-1 |
0.467 |
|
| 1990 |
Mannie MD, Paterson PY, U'Prichard DC, Flouret G. The N- and C-terminal boundaries of myelin basic protein determinants required for encephalitogenic and proliferative responses of Lewis rat T cells. Journal of Neuroimmunology. 26: 201-11. PMID 1689742 DOI: 10.1016/0165-5728(90)90002-5 |
0.463 |
|
| 1989 |
Mannie MD, Paterson PY, U'Prichard DC, Thomas DW. Clonotypic heterogeneity of Lewis rat T cells specific for the encephalitogenic 68-86 region of myelin basic protein. Cellular Immunology. 122: 534-47. PMID 2475260 DOI: 10.1016/0008-8749(89)90099-3 |
0.485 |
|
| 1989 |
Mannie MD, Pope L, Paterson PY. Indomethacin augments in vitro proliferative responses of Lewis rat lymphocytes to myelin basic protein. Implications for experimental autoimmune encephalomyelitis. Cellular Immunology. 121: 196-212. PMID 2470519 DOI: 10.1016/0008-8749(89)90017-8 |
0.492 |
|
| 1985 |
Mannie MD, Paterson PY, U'Prichard DC, Flouret G. Induction of experimental allergic encephalomyelitis in Lewis rats with purified synthetic peptides: delineation of antigenic determinants for encephalitogenicity, in vitro activation of cellular transfer, and proliferation of lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 82: 5515-9. PMID 3875098 DOI: 10.1073/Pnas.82.16.5515 |
0.357 |
|
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