| Year |
Citation |
Score |
| 2023 |
Wu CG, Balakrishnan VK, Merrill RA, Parihar PS, Konovolov K, Chen YC, Xu Z, Wei H, Sundaresan R, Cui Q, Wadzinski BE, Swingle MR, Musiyenko A, Chung WK, Honkanen RE, et al. B56δ long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan's syndrome mutations. Proceedings of the National Academy of Sciences of the United States of America. 121: e2310727120. PMID 38150499 DOI: 10.1073/pnas.2310727120 |
0.712 |
|
| 2023 |
Smolen KA, Papke CM, Swingle MR, Musiyenko A, Li C, Salter EA, Camp AD, Honkanen RE, Kettenbach AN. Quantitative proteomics and phosphoproteomics of PP2A-PPP2R5D variants reveal deregulation of RPS6 phosphorylation via converging signaling cascades. The Journal of Biological Chemistry. 105154. PMID 37572851 DOI: 10.1016/j.jbc.2023.105154 |
0.724 |
|
| 2023 |
Salter EA, Wierzbicki A, Honkanen RE, Swingle MR. Quantum-based modeling implies that bidentate Arg-substrate binding enhances serine/threonine protein phosphatase-2A(PPP2R5D/PPP2R1A/PPP2CA)-mediated dephosphorylation. Frontiers in Cell and Developmental Biology. 11: 1141804. PMID 37377738 DOI: 10.3389/fcell.2023.1141804 |
0.708 |
|
| 2023 |
Wu CG, Balakrishnan VK, Parihar PS, Konovolov K, Chen YC, Merrill RA, Wei H, Carragher B, Sundaresan R, Cui Q, Wadzinski BE, Swingle MR, Musiyenko A, Honkanen R, Chung WK, et al. Extended regulation interface coupled to the allosteric network and disease mutations in the PP2A-B56δ holoenzyme. Biorxiv : the Preprint Server For Biology. PMID 37066309 DOI: 10.1101/2023.03.09.530109 |
0.7 |
|
| 2021 |
Shuhaibar LC, Kaci N, Egbert JR, Horville T, Loisay L, Vigone G, Uliasz TF, Dambroise E, Swingle MR, Honkanen RE, Biosse Duplan M, Jaffe LA, Legeai-Mallet L. Phosphatase inhibition by LB-100 enhances BMN-111 stimulation of bone growth. Jci Insight. 6. PMID 33986191 DOI: 10.1172/jci.insight.141426 |
0.688 |
|
| 2021 |
Papke CM, Smolen KA, Swingle MR, Cressey L, Heng RA, Toporsian M, Deng L, Hagen J, Shen Y, Chung WK, Kettenbach AN, Honkanen RE. A disorder-related variant (E420K) of a PP2A-regulatory subunit (PPP2R5D) causes constitutively active AKT-mTOR signaling and uncoordinated cell growth. The Journal of Biological Chemistry. 100313. PMID 33482199 DOI: 10.1016/j.jbc.2021.100313 |
0.678 |
|
| 2019 |
D'Arcy BM, Swingle MR, Schambeau L, Pannell L, Prakash A, Honkanen RE. Development of a Synthetic 3-ketosteroid Δ-dehydrogenase for the Generation of a Novel Catabolic Pathway Enabling Cholesterol Degradation in Human Cells. Scientific Reports. 9: 5969. PMID 30979909 DOI: 10.1038/S41598-019-42046-8 |
0.663 |
|
| 2019 |
D'Arcy BM, Swingle MR, Papke CM, Abney KA, Bouska ES, Prakash A, Honkanen RE. The Antitumor Drug LB-100 is a Catalytic Inhibitor of Protein Phosphatase 2A (PPP2CA) and 5 (PPP5C) Coordinating with the Catalytic Metals in the Active Site of PP5C. Molecular Cancer Therapeutics. PMID 30679389 DOI: 10.1158/1535-7163.Mct-17-1143 |
0.721 |
|
| 2018 |
Swingle MR, Honkanen RE. Inhibitors of Serine/Threonine Protein Phosphatases: Biochemical and Structural Studies Provide Insight for Further Development. Current Medicinal Chemistry. PMID 29737249 DOI: 10.2174/0929867325666180508095242 |
0.735 |
|
| 2017 |
Choy MS, Swingle M, D'Arcy B, Abney K, Rusin SF, Kettenbach AN, Page R, Honkanen RE, Peti W. The PP1:tautomycetin complex reveals a path towards the development of PP1-specific inhibitors. Journal of the American Chemical Society. PMID 29156132 DOI: 10.1021/Jacs.7B09368 |
0.727 |
|
| 2016 |
Swingle M, Volmar CH, Saldanha SA, Chase P, Eberhart C, Salter EA, D'Arcy B, Schroeder CE, Golden JE, Wierzbicki A, Hodder P, Honkanen RE. An Ultra-High-Throughput Screen for Catalytic Inhibitors of Serine/Threonine Protein Phosphatases Types 1 and 5 (PP1C and PP5C). Journal of Biomolecular Screening. PMID 27628691 DOI: 10.1177/1087057116668852 |
0.713 |
|
| 2016 |
Chattopadhyay D, Swingle MR, Salter EA, Wood E, D'Arcy B, Zivanov C, Abney K, Musiyenko A, Rusin SF, Kettenbach A, Yet L, Schroeder CE, Golden JE, Dunham WH, Gingras AC, ... ... Honkanen RE, et al. Crystal Structures and Mutagenesis of PPP-family ser/thr Protein Phosphatases Elucidate the Selectivity of Cantharidin and Novel Norcantharidin-based Inhibitors of PP5C. Biochemical Pharmacology. PMID 27002182 DOI: 10.1016/J.Bcp.2016.03.011 |
0.724 |
|
| 2014 |
Swingle MR, Honkanen RE. Development and validation of a robust and sensitive assay for the discovery of selective inhibitors for serine/threonine protein phosphatases PP1α (PPP1C) and PP5 (PPP5C). Assay and Drug Development Technologies. 12: 481-96. PMID 25383722 DOI: 10.1089/adt.2014.603 |
0.734 |
|
| 2014 |
Mazalouskas MD, Godoy-Ruiz R, Weber DJ, Zimmer DB, Honkanen RE, Wadzinski BE. Small G proteins Rac1 and Ras regulate serine/threonine protein phosphatase 5 (PP5)·extracellular signal-regulated kinase (ERK) complexes involved in the feedback regulation of Raf1. The Journal of Biological Chemistry. 289: 4219-32. PMID 24371145 DOI: 10.1074/Jbc.M113.518514 |
0.355 |
|
| 2014 |
Fransson L, Rosengren V, Saha TK, Grankvist N, Islam T, Honkanen RE, Sjöholm Å, Ortsäter H. Mitogen-activated protein kinases and protein phosphatase 5 mediate glucocorticoid-induced cytotoxicity in pancreatic islets and β-cells. Molecular and Cellular Endocrinology. 383: 126-36. PMID 24361515 DOI: 10.1016/j.mce.2013.12.010 |
0.301 |
|
| 2011 |
Amable L, Grankvist N, Largen JW, Ortsäter H, Sjöholm Å, Honkanen RE. Disruption of serine/threonine protein phosphatase 5 (PP5:PPP5c) in mice reveals a novel role for PP5 in the regulation of ultraviolet light-induced phosphorylation of serine/threonine protein kinase Chk1 (CHEK1). The Journal of Biological Chemistry. 286: 40413-22. PMID 21921034 DOI: 10.1074/jbc.M111.244053 |
0.343 |
|
| 2011 |
Yang X, Liu Y, Yang XM, Hu F, Cui L, Swingle MR, Honkanen RE, Soltani P, Tissier R, Cohen MV, Downey JM. Cardioprotection by mild hypothermia during ischemia involves preservation of ERK activity. Basic Research in Cardiology. 106: 421-30. PMID 21399968 DOI: 10.1007/s00395-011-0165-0 |
0.7 |
|
| 2010 |
Burke CP, Swingle MR, Honkanen RE, Boger DL. Total synthesis and evaluation of phostriecin and key structural analogues. The Journal of Organic Chemistry. 75: 7505-13. PMID 20669916 DOI: 10.1021/Jo1010203 |
0.71 |
|
| 2009 |
Swingle MR, Amable L, Lawhorn BG, Buck SB, Burke CP, Ratti P, Fischer KL, Boger DL, Honkanen RE. Structure-activity relationship studies of fostriecin, cytostatin, and key analogs, with PP1, PP2A, PP5, and( beta12-beta13)-chimeras (PP1/PP2A and PP5/PP2A), provide further insight into the inhibitory actions of fostriecin family inhibitors. The Journal of Pharmacology and Experimental Therapeutics. 331: 45-53. PMID 19592665 DOI: 10.1124/Jpet.109.155630 |
0.754 |
|
| 2008 |
Golden T, Aragon IV, Rutland B, Tucker JA, Shevde LA, Samant RS, Zhou G, Amable L, Skarra D, Honkanen RE. Elevated levels of Ser/Thr protein phosphatase 5 (PP5) in human breast cancer. Biochimica Et Biophysica Acta. 1782: 259-70. PMID 18280813 DOI: 10.1016/J.Bbadis.2008.01.004 |
0.504 |
|
| 2008 |
Golden T, Swingle M, Honkanen RE. The role of serine/threonine protein phosphatase type 5 (PP5) in the regulation of stress-induced signaling networks and cancer. Cancer Metastasis Reviews. 27: 169-78. PMID 18253812 DOI: 10.1007/S10555-008-9125-Z |
0.707 |
|
| 2007 |
Ni L, Swingle MS, Bourgeois AC, Honkanen RE. High yield expression of serine/threonine protein phosphatase type 5, and a fluorescent assay suitable for use in the detection of catalytic inhibitors. Assay and Drug Development Technologies. 5: 645-53. PMID 17939754 DOI: 10.1089/Adt.2007.079 |
0.758 |
|
| 2007 |
Swingle M, Ni L, Honkanen RE. Small-molecule inhibitors of ser/thr protein phosphatases: specificity, use and common forms of abuse. Methods in Molecular Biology (Clifton, N.J.). 365: 23-38. PMID 17200551 DOI: 10.1385/1-59745-267-X:23 |
0.745 |
|
| 2007 |
Boger D, Lawhorn B, Boga S, Wolkenberg S, Colby D, Gauss C, Swingle M, Amable L, Honkanen R. Synthesis of Cytostatin Synfacts. 2007: 0456-0456. DOI: 10.1055/S-2007-968390 |
0.643 |
|
| 2006 |
Lawhorn BG, Boga SB, Wolkenberg SE, Colby DA, Gauss CM, Swingle MR, Amable L, Honkanen RE, Boger DL. Total synthesis and evaluation of cytostatin, its C10-C11 diastereomers, and additional key analogues: impact on PP2A inhibition. Journal of the American Chemical Society. 128: 16720-32. PMID 17177422 DOI: 10.1021/Ja066477D |
0.681 |
|
| 2004 |
Golden T, Aragon IV, Zhou G, Cooper SR, Dean NM, Honkanen RE. Constitutive over expression of serine/threonine protein phosphatase 5 (PP5) augments estrogen-dependent tumor growth in mice. Cancer Letters. 215: 95-100. PMID 15374638 DOI: 10.1016/J.Canlet.2004.03.027 |
0.525 |
|
| 2004 |
Zhou G, Golden T, Aragon IV, Honkanen RE. Ser/Thr protein phosphatase 5 inactivates hypoxia-induced activation of an apoptosis signal-regulating kinase 1/MKK-4/JNK signaling cascade. The Journal of Biological Chemistry. 279: 46595-605. PMID 15328343 DOI: 10.1074/Jbc.M408320200 |
0.575 |
|
| 2004 |
Swingle MR, Honkanen RE, Ciszak EM. Structural basis for the catalytic activity of human serine/threonine protein phosphatase-5. The Journal of Biological Chemistry. 279: 33992-9. PMID 15155720 DOI: 10.1074/jbc.M402855200 |
0.714 |
|
| 2003 |
Buck SB, Hardouin C, Ichikawa S, Soenen DR, Gauss CM, Hwang I, Swingle MR, Bonness KM, Honkanen RE, Boger DL. Fundamental role of the fostriecin unsaturated lactone and implications for selective protein phosphatase inhibition. Journal of the American Chemical Society. 125: 15694-5. PMID 14677930 DOI: 10.1021/Ja038672N |
0.724 |
|
| 2003 |
Honkanen RE, Golden T. Regulators of serine/threonine protein phosphatases at the dawn of a clinical era? Current Medicinal Chemistry. 9: 2055-75. PMID 12369870 DOI: 10.2174/0929867023368836 |
0.386 |
|
| 2001 |
Dean DA, Urban G, Aragon IV, Swingle M, Miller B, Rusconi S, Bueno M, Dean NM, Honkanen RE. Serine/threonine protein phosphatase 5 (PP5) participates in the regulation of glucocorticoid receptor nucleocytoplasmic shuttling. Bmc Cell Biology. 2: 6. PMID 11389770 DOI: 10.1186/1471-2121-2-6 |
0.695 |
|
| 2001 |
Sjöholm A, Berggren PO, Honkanen RE. Effects of second messengers on serine/threonine protein phosphatases in insulin-secreting cells. Biochemical and Biophysical Research Communications. 283: 364-8. PMID 11327709 DOI: 10.1006/bbrc.2001.4789 |
0.331 |
|
| 2000 |
Huang X, Swingle MR, Honkanen RE. Photoreceptor serine/threonine protein phosphatase type 7: cloning, expression, and functional analysis. Methods in Enzymology. 315: 579-93. PMID 10736728 |
0.686 |
|
| 2000 |
Sjöholm A, Honkanen RE. Polyamines regulate serine/threonine protein phosphatases in insulin-secreting cells. Pancreas. 20: 32-7. PMID 10630381 DOI: 10.1097/00006676-200001000-00005 |
0.347 |
|
| 1999 |
Connor JH, Kleeman T, Barik S, Honkanen RE, Shenolikar S. Importance of the beta12-beta13 loop in protein phosphatase-1 catalytic subunit for inhibition by toxins and mammalian protein inhibitors. The Journal of Biological Chemistry. 274: 22366-72. PMID 10428807 DOI: 10.1074/jbc.274.32.22366 |
0.319 |
|
| 1997 |
Walsh AH, Cheng A, Honkanen RE. Fostriecin, an antitumor antibiotic with inhibitory activity against serine/threonine protein phosphatases types 1 (PP1) and 2A (PP2A), is highly selective for PP2A. Febs Letters. 416: 230-4. PMID 9373158 DOI: 10.1016/S0014-5793(97)01210-6 |
0.318 |
|
| 1994 |
Honkanen RE, Codispoti BA, Tse K, Boynton AL, Honkanan RE. Characterization of natural toxins with inhibitory activity against serine/threonine protein phosphatases. Toxicon : Official Journal of the International Society On Toxinology. 32: 339-50. PMID 8016855 DOI: 10.1016/0041-0101(94)90086-8 |
0.333 |
|
| 1993 |
Honkanen RE. Cantharidin, another natural toxin that inhibits the activity of serine/threonine protein phosphatases types 1 and 2A. Febs Letters. 330: 283-6. PMID 8397101 DOI: 10.1016/0014-5793(93)80889-3 |
0.342 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 1995 |
Sjöholm A, Honkanen RE, Berggren PO. Inhibition of serine/threonine protein phosphatases by secretagogues in insulin-secreting cells. Endocrinology. 136: 3391-7. PMID 7628374 DOI: 10.1210/endo.136.8.7628374 |
0.294 |
|
| 1998 |
Huang X, Honkanen RE. Molecular cloning, expression, and characterization of a novel human serine/threonine protein phosphatase, PP7, that is homologous to Drosophila retinal degeneration C gene product (rdgC). The Journal of Biological Chemistry. 273: 1462-8. PMID 9430683 DOI: 10.1074/jbc.273.3.1462 |
0.288 |
|
| 2000 |
Cheng A, Dean NM, Honkanen RE. Serine/threonine protein phosphatase type 1gamma1 is required for the completion of cytokinesis in human A549 lung carcinoma cells. The Journal of Biological Chemistry. 275: 1846-54. PMID 10636884 DOI: 10.1074/jbc.275.3.1846 |
0.283 |
|
| 2012 |
Grankvist N, Amable L, Honkanen RE, Sjöholm A, Ortsäter H. Serine/threonine protein phosphatase 5 regulates glucose homeostasis in vivo and apoptosis signalling in mouse pancreatic islets and clonal MIN6 cells. Diabetologia. 55: 2005-15. PMID 22526606 DOI: 10.1007/s00125-012-2541-1 |
0.268 |
|
| 1999 |
Zuo Z, Urban G, Scammell JG, Dean NM, McLean TK, Aragon I, Honkanen RE. Ser/Thr protein phosphatase type 5 (PP5) is a negative regulator of glucocorticoid receptor-mediated growth arrest. Biochemistry. 38: 8849-57. PMID 10413457 DOI: 10.1021/bi990842e |
0.268 |
|
| 1997 |
Honkanen RE, Stapleton JD, Bryan DE, Abercrombie J. Development of a protein phosphatase-based assay for the detection of phosphatase inhibitors in crude whole cell and animal extracts. Toxicon : Official Journal of the International Society On Toxinology. 34: 1385-92. PMID 9027995 DOI: 10.1016/S0041-0101(96)00095-5 |
0.264 |
|
| 2012 |
Henesy MB, Britain AL, Zhu B, Amable L, Honkanen RE, Corbin JD, Francis SH, Rich TC. Calcineurin regulates homologous desensitization of natriuretic peptide receptor-A and inhibits ANP-induced testosterone production in MA-10 cells. Plos One. 7: e41711. PMID 22876290 DOI: 10.1371/Journal.Pone.0041711 |
0.258 |
|
| 2013 |
Theobald B, Bonness K, Musiyenko A, Andrews JF, Urban G, Huang X, Dean NM, Honkanen RE. Suppression of Ser/Thr phosphatase 4 (PP4C/PPP4C) mimics a novel post-mitotic action of fostriecin, producing mitotic slippage followed by tetraploid cell death. Molecular Cancer Research : McR. 11: 845-55. PMID 23671329 DOI: 10.1158/1541-7786.MCR-13-0032 |
0.257 |
|
| 2011 |
Bhardwaj A, Singh S, Srivastava SK, Honkanen RE, Reed E, Singh AP. Modulation of protein phosphatase 2A activity alters androgen-independent growth of prostate cancer cells: therapeutic implications. Molecular Cancer Therapeutics. 10: 720-31. PMID 21393425 DOI: 10.1158/1535-7163.MCT-10-1096 |
0.256 |
|
| 2021 |
Jeong K, Murphy JM, Kim JH, Campbell PM, Park H, Rodriguez Y, Choi C, Kim JS, Park S, Kim HJ, Scammell JG, Weber DS, Honkanen RE, Schlaepfer DD, Ahn EE, et al. FAK Activation Promotes SMC Dedifferentiation via Increased DNA Methylation in Contractile Genes. Circulation Research. PMID 34702049 DOI: 10.1161/CIRCRESAHA.121.319066 |
0.247 |
|
| 1994 |
Sjöholm A, Honkanen RE, Berggren PO. Characterization of serine/threonine protein phosphatases in RINm5F insulinoma cells. Bioscience Reports. 13: 349-58. PMID 8204804 DOI: 10.1007/BF01150479 |
0.24 |
|
| 1994 |
Ämmälä C, Eliasson L, Bokvist K, Berggren PO, Honkanen RE, Sjöholm A, Rorsman P. Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in mouse pancreatic β cells Proceedings of the National Academy of Sciences of the United States of America. 91: 4343-4347. PMID 8183910 DOI: 10.1073/Pnas.91.10.4343 |
0.238 |
|
| 1998 |
Zuo Z, Dean NM, Honkanen RE. Serine/threonine protein phosphatase type 5 acts upstream of p53 to regulate the induction of p21(WAF1/Cip1) and mediate growth arrest. The Journal of Biological Chemistry. 273: 12250-8. PMID 9575175 DOI: 10.1074/jbc.273.20.12250 |
0.238 |
|
| 2011 |
Skarra DV, Goudreault M, Choi H, Mullin M, Nesvizhskii AI, Gingras AC, Honkanen RE. Label-free quantitative proteomics and SAINT analysis enable interactome mapping for the human Ser/Thr protein phosphatase 5 Proteomics. 11: 1508-1516. PMID 21360678 DOI: 10.1002/Pmic.201000770 |
0.234 |
|
| 2012 |
Mitra A, Menezes ME, Pannell LK, Mulekar MS, Honkanen RE, Shevde LA, Samant RS. DNAJB6 chaperones PP2A mediated dephosphorylation of GSK3β to downregulate β-catenin transcription target, osteopontin. Oncogene. 31: 4472-83. PMID 22266849 DOI: 10.1038/Onc.2011.623 |
0.233 |
|
| 2008 |
Chen YW, Cleaver JE, Hatahet Z, Honkanen RE, Chang JY, Yen Y, Chou KM. Human DNA polymerase eta activity and translocation is regulated by phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 105: 16578-83. PMID 18946034 DOI: 10.1073/Pnas.0808589105 |
0.232 |
|
| 1997 |
Larsson O, Barker CJ, Sjöholm A, Carlqvist H, Michell RH, Bertorello A, Nilsson T, Honkanen RE, Mayr GW, Zwiller J, Berggren PO. Inhibition of phosphatases and increased Ca2+ channel activity by inositol hexakisphosphate. Science (New York, N.Y.). 278: 471-4. PMID 9334307 DOI: 10.1126/Science.278.5337.471 |
0.225 |
|
| 2003 |
Golden TA, Honkanen RE. Regulating the expression of protein phosphatase type 5. Methods in Enzymology. 366: 372-90. PMID 14674262 |
0.225 |
|
| 1995 |
Honkanen RE, Caplan FR, Baker KK, Baldwin CL, Bobrin SC, Bolis CM, Cabrera GM, Johnson LA, Jung JH, Larsen LK, Levine IA, Moore RE, Nelson CS, Patterson GML, Tschappat KD, et al. Protein phosphatase inhibitory activity in extracts of cultured blue-green algae (cyanophyta) Journal of Phycology. 31: 478-486. DOI: 10.1111/J.0022-3646.1995.00478.X |
0.224 |
|
| 2003 |
Urban G, Golden T, Aragon IV, Cowsert L, Cooper SR, Dean NM, Honkanen RE. Identification of a functional link for the p53 tumor suppressor protein in dexamethasone-induced growth suppression. The Journal of Biological Chemistry. 278: 9747-53. PMID 12519780 DOI: 10.1074/jbc.M210993200 |
0.223 |
|
| 1997 |
Huang X, Cheng A, Honkanen RE. Genomic organization of the human PP4 gene encoding a serine/threonine protein phosphatase (PP4) suggests a common ancestry with PP2A. Genomics. 44: 336-43. PMID 9325055 DOI: 10.1006/geno.1997.4891 |
0.222 |
|
| 2020 |
Haldar B, Hamilton CL, Solodushko V, Abney KA, Alexeyev M, Honkanen RE, Scammell JG, Cioffi DL. S100A6 is a positive regulator of PPP5C-FKBP51-dependent regulation of endothelial calcium signaling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 31916625 DOI: 10.1096/fj.201901777R |
0.221 |
|
| 1990 |
Mordan LJ, Dean NM, Honkanen RE, Boynton AL. Okadaic acid: a reversible inhibitor of neoplastic transformation of mouse fibroblasts. Cancer Communications. 2: 237-41. PMID 2165798 DOI: 10.3727/095535490820874290 |
0.216 |
|
| 2001 |
Urban G, Golden T, Aragon IV, Scammell JG, Dean NM, Honkanen RE. Identification of an estrogen-inducible phosphatase (PP5) that converts MCF-7 human breast carcinoma cells into an estrogen-independent phenotype when expressed constitutively. The Journal of Biological Chemistry. 276: 27638-46. PMID 11331294 DOI: 10.1074/jbc.M103512200 |
0.205 |
|
| 2004 |
Lehtihet M, Honkanen RE, Sjöholm A. Inositol hexakisphosphate and sulfonylureas regulate beta-cell protein phosphatases. Biochemical and Biophysical Research Communications. 316: 893-7. PMID 15033485 DOI: 10.1016/j.bbrc.2004.02.144 |
0.203 |
|
| 2002 |
Golden T, Dean NM, Honkanen RE. Use of antisense oligonucleotides: advantages, controls, and cardiovascular tissue. Microcirculation (New York, N.Y. : 1994). 9: 51-64. PMID 11896559 DOI: 10.1038/sj/mn/7800121 |
0.19 |
|
| 2015 |
Salter EA, Honkanen RE, Wierzbicki A. Modeling the antiferromagnetic MnIIMnII system within the protein phosphatase-5 catalytic site. Journal of Molecular Modeling. 21: 14. PMID 25617208 DOI: 10.1007/s00894-014-2556-2 |
0.187 |
|
| 1990 |
Zwiller J, Honkanen RE, Boynton AL. Stimulation of DNA synthesis by an inositol polyphosphate-activated protein phosphatase in calcium-deprived rat liver cells. Experimental Cell Research. 187: 193-6. PMID 2156716 DOI: 10.1016/0014-4827(90)90081-K |
0.186 |
|
| 2014 |
Ortsäter H, Grankvist N, Honkanen RE, Sjöholm Å. Protein phosphatases in pancreatic islets. The Journal of Endocrinology. 221: R121-44. PMID 24681827 DOI: 10.1530/JOE-14-0002 |
0.185 |
|
| 1997 |
Diwan AH, Honkanen RE, Schaeffer RC, Strada SJ, Thompson WJ. Inhibition of serine-threonine protein phosphatases decreases barrier function of rat pulmonary microvascular endothelial cells. Journal of Cellular Physiology. 171: 259-70. PMID 9180895 DOI: 10.1002/(SICI)1097-4652(199706)171:3<259::AID-JCP4>3.0.CO;2-N |
0.179 |
|
| 2006 |
Bonness K, Aragon IV, Rutland B, Ofori-Acquah S, Dean NM, Honkanen RE. Cantharidin-induced mitotic arrest is associated with the formation of aberrant mitotic spindles and lagging chromosomes resulting, in part, from the suppression of PP2Aalpha. Molecular Cancer Therapeutics. 5: 2727-36. PMID 17121919 DOI: 10.1158/1535-7163.MCT-06-0273 |
0.17 |
|
| 2005 |
Lehtihet M, Webb DL, Honkanen RE, Sjöholm A. Glutamate inhibits protein phosphatases and promotes insulin exocytosis in pancreatic beta-cells. Biochemical and Biophysical Research Communications. 328: 601-7. PMID 15694391 DOI: 10.1016/j.bbrc.2005.01.024 |
0.168 |
|
| 2012 |
Bouazza B, Krytska K, Debba-Pavard M, Amrani Y, Honkanen RE, Tran J, Tliba O. Cytokines alter glucocorticoid receptor phosphorylation in airway cells: role of phosphatases. American Journal of Respiratory Cell and Molecular Biology. 47: 464-73. PMID 22592921 DOI: 10.1165/rcmb.2011-0364OC |
0.167 |
|
| 2013 |
Lehtihet M, Webb D, Honkanen RE, Sjöholm Å. Corrigendum to “Glutamate inhibits protein phosphatases and promotes insulin exocytosis in pancreatic b-cells” [Biochem. Biophys. Res. Commun. 438 (2005) 601–607] Biochemical and Biophysical Research Communications. 441: 273. DOI: 10.1016/j.bbrc.2013.10.061 |
0.166 |
|
| 1989 |
Honkanen RE, Abdel-Latif AA. Muscarinic-agonist and guanine nucleotide stimulation of myo-inositol trisphosphate formation in membranes isolated from bovine iris sphincter smooth muscle: effects of short-term cholinergic desensitization. Membrane Biochemistry. 8: 39-59. PMID 2554097 DOI: 10.3109/09687688909025825 |
0.161 |
|
| 2023 |
Janssens V, Wadzinski BE, Li C, Honkanen RE. Editorial: Deciphering the etiology of rare genetic disorders associated with protein phosphatases. Frontiers in Cell and Developmental Biology. 11: 1241606. PMID 37645249 DOI: 10.3389/fcell.2023.1241606 |
0.16 |
|
| 2002 |
Sjöholm A, Lehtihet M, Efanov AM, Zaitsev SV, Berggren PO, Honkanen RE. Glucose metabolites inhibit protein phosphatases and directly promote insulin exocytosis in pancreatic beta-cells. Endocrinology. 143: 4592-8. PMID 12446586 DOI: 10.1210/en.2002-220672 |
0.154 |
|
| 2017 |
Hamilton CL, Abney KA, Vasauskas AA, Alexeyev M, Li N, Honkanen RE, Scammell JG, Cioffi DL. EXPRESS: Serine/threonine phosphatase 5 (PP5C/PPP5C) regulates the ISOC channel through a PP5C-FKBP51 axis. Pulmonary Circulation. 2045893217753156. PMID 29283027 DOI: 10.1177/2045893217753156 |
0.137 |
|
| 1996 |
Honkanen RE, Mowdy DE, Dickey RW. Detection of DSP-Toxins, Okadaic Acid, and Dinophysis Toxin-1 in Shellfish by Serine/Threonine Protein Phosphatase Assay Journal of Aoac International. 79: 1336-1343. DOI: 10.1093/jaoac/79.6.1336 |
0.13 |
|
| 1988 |
Honkanen RE, Abdel-Latif AA. Characterization of cholinergic muscarinic receptors in the rabbit iris. Biochemical Pharmacology. 37: 2575-83. PMID 3291881 DOI: 10.1016/0006-2952(88)90249-3 |
0.114 |
|
| 2013 |
Grankvist N, Honkanen RE, Sjöholm Å, Ortsäter H. Genetic disruption of protein phosphatase 5 in mice prevents high-fat diet feeding-induced weight gain. Febs Letters. 587: 3869-74. PMID 24220247 DOI: 10.1016/j.febslet.2013.10.022 |
0.075 |
|
| 1988 |
Honkanen RE, Abdel-Latif AA. AFDX-116 discriminates between muscarinic M2 receptors of the heart and the iris smooth muscle. Molecular and Cellular Biochemistry. 82: 131-5. PMID 3185518 DOI: 10.1007/BF00242528 |
0.07 |
|
| 2019 |
D'Arcy BM, Prakash A, Honkanen RE. Targeting phosphatases in cancer: suppression of many versus the ablation of one. Oncotarget. 10: 6543-6545. PMID 31762936 DOI: 10.18632/Oncotarget.27201 |
0.067 |
|
| 1999 |
Wang L, Bhattacharjee A, Zuo Z, Hu F, Honkanen RE, Berggren PO, Li M. A Low Voltage-Activated Ca2+ Current Mediates Cytokine-Induced Pancreatic β-Cell Death. Endocrinology. 140: 1200-1204. PMID 28200631 DOI: 10.1210/endo.140.3.6556 |
0.064 |
|
| 2020 |
Haldar B, Hamilton CL, Solodushko V, Honkanen RE, Scammell JG, Cioffi DL. Calcium‐Dependent Localization of S100A6 in Pulmonary Microvascular Endothelial Cells The Faseb Journal. 34: 1-1. DOI: 10.1096/fasebj.2020.34.s1.01993 |
0.013 |
|
| 2014 |
Honkanen MH, Honkanen RE. Managing the Statin Intolerant Patient: Low-Dose/ Low-Frequency Treatment Regimens Journal of Clinical Lipidology. 8: 338-339. DOI: 10.1016/J.JACL.2014.02.068 |
0.013 |
|
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