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William C. Sessa - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
Vascular Biology
Website:
http://medicine.yale.edu/pharm/people/william_sessa.profile

111 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Jin Y, Xie Y, Ostriker AC, Zhang X, Liu R, Lee MY, Leslie KL, Tang W, Du J, Lee SH, Wang Y, Sessa WC, Hwa J, Yu J, Martin KA. Opposing Actions of AKT (Protein Kinase B) Isoforms in Vascular Smooth Muscle Injury and Therapeutic Response. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 29025710 DOI: 10.1161/ATVBAHA.117.310053  0.4
2017 MacLauchlan SC, Calabro NE, Huang Y, Krishna M, Bancroft T, Sharma T, Yu J, Sessa WC, Giordano F, Kyriakides TR. HIF-1α represses the expression of the angiogenesis inhibitor thrombospondin-2. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 28789925 DOI: 10.1016/j.matbio.2017.07.002  0.4
2017 Nakamura T, Fujiwara Y, Yamada R, Fujii W, Hamabata T, Lee MY, Maeda S, Aritake K, Roers A, Sessa WC, Nakamura M, Urade Y, Murata T. Mast cell-derived prostaglandin D2 attenuates anaphylactic reactions in mice. The Journal of Allergy and Clinical Immunology. PMID 28457595 DOI: 10.1016/j.jaci.2017.02.030  0.36
2016 Ulrich V, Rotllan N, Araldi E, Luciano A, Skroblin P, Abonnenc M, Perrotta P, Yin X, Bauer A, Leslie KL, Zhang P, Aryal B, Montgomery RL, Thum T, Martin K, ... ... Sessa WC, et al. Chronic miR-29 antagonism promotes favorable plaque remodeling in atherosclerotic mice. Embo Molecular Medicine. PMID 27137489 DOI: 10.15252/emmm.201506031  0.44
2016 Liu D, Lei L, Desir M, Huang Y, Cleman J, Jiang W, Fernandez-Hernando C, Di Lorenzo A, Sessa WC, Giordano FJ. Smooth Muscle Hypoxia-Inducible Factor 1α Links Intravascular Pressure and Atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 26800562 DOI: 10.1161/ATVBAHA.115.306861  0.44
2016 Park EJ, Grabińska KA, Guan Z, Sessa WC. NgBR is essential for endothelial cell glycosylation and vascular development. Embo Reports. PMID 26755743 DOI: 10.15252/embr.201540789  0.44
2016 Marin EP, Jozsef L, Di Lorenzo A, Held KF, Luciano AK, Melendez J, Milstone LM, Velazquez H, Sessa WC. The Protein Acyl Transferase ZDHHC21 Modulates α1 Adrenergic Receptor Function and Regulates Hemodynamics. Arteriosclerosis, Thrombosis, and Vascular Biology. 36: 370-9. PMID 26715683 DOI: 10.1161/ATVBAHA.115.306942  0.44
2015 Chamorro-Jorganes A, Lee MY, Araldi E, Landskroner-Eiger S, Fernandez-Fuertes M, Sahraei M, Quiles Del Rey M, van Solingen C, Yu J, Fernandez-Hernando C, Sessa WC, Suarez Y. VEGF-Induced Expression of miR-17~92 Cluster in Endothelial Cells is Mediated by ERK/ELK1 Activation and Regulates Angiogenesis. Circulation Research. PMID 26472816 DOI: 10.1161/CIRCRESAHA.115.307408  0.4
2015 Landskroner-Eiger S, Qiu C, Perrotta P, Siragusa M, Lee MY, Ulrich V, Luciano AK, Zhuang ZW, Corti F, Simons M, Montgomery RL, Wu D, Yu J, Sessa WC. Endothelial miR-17∼92 cluster negatively regulates arteriogenesis via miRNA-19 repression of WNT signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 26417068 DOI: 10.1073/pnas.1507094112  0.44
2015 Xie Y, Jin Y, Merenick BL, Ding M, Fetalvero KM, Wagner RJ, Mai A, Gleim S, Tucker DF, Birnbaum MJ, Ballif BA, Luciano AK, Sessa WC, Rzucidlo EM, Powell RJ, et al. Phosphorylation of GATA-6 is required for vascular smooth muscle cell differentiation after mTORC1 inhibition. Science Signaling. 8: ra44. PMID 25969542 DOI: 10.1126/scisignal.2005482  0.44
2015 Goodwin JE, Zhang X, Rotllan N, Feng Y, Zhou H, Fernández-Hernando C, Yu J, Sessa WC. Endothelial glucocorticoid receptor suppresses atherogenesis--brief report. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 779-82. PMID 25810297 DOI: 10.1161/ATVBAHA.114.304525  0.44
2015 Rotllan N, Chamorro-Jorganes A, Araldi E, Wanschel AC, Aryal B, Aranda JF, Goedeke L, Salerno AG, Ramírez CM, Sessa WC, Suárez Y, Fernández-Hernando C. Hematopoietic Akt2 deficiency attenuates the progression of atherosclerosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 597-610. PMID 25392271 DOI: 10.1096/fj.14-262097  0.44
2015 Bancroft T, Bouaouina M, Roberts S, Lee M, Calderwood DA, Schwartz M, Simons M, Sessa WC, Kyriakides TR. Up-regulation of thrombospondin-2 in Akt1-null mice contributes to compromised tissue repair due to abnormalities in fibroblast function. The Journal of Biological Chemistry. 290: 409-22. PMID 25389299 DOI: 10.1074/jbc.M114.618421  0.44
2015 Pober JS, Sessa WC. Inflammation and the blood microvascular system. Cold Spring Harbor Perspectives in Biology. 7: a016345. PMID 25384307 DOI: 10.1101/cshperspect.a016345  0.44
2014 Goodwin JE, Feng Y, Velazquez H, Zhou H, Sessa WC. Loss of the endothelial glucocorticoid receptor prevents the therapeutic protection afforded by dexamethasone after LPS. Plos One. 9: e108126. PMID 25299055 DOI: 10.1371/journal.pone.0108126  0.44
2014 Lee MY, Luciano AK, Ackah E, Rodriguez-Vita J, Bancroft TA, Eichmann A, Simons M, Kyriakides TR, Morales-Ruiz M, Sessa WC. Endothelial Akt1 mediates angiogenesis by phosphorylating multiple angiogenic substrates. Proceedings of the National Academy of Sciences of the United States of America. 111: 12865-70. PMID 25136137 DOI: 10.1073/pnas.1408472111  0.44
2014 Park EJ, Grabi?ska KA, Guan Z, Stránecký V, Hartmannová H, Hoda?ová K, Barešová V, Sovová J, Jozsef L, Ondrušková N, Hansíková H, Honzík T, Zeman J, H?lková H, Wen R, ... ... Sessa WC, et al. Mutation of Nogo-B receptor, a subunit of cis-prenyltransferase, causes a congenital disorder of glycosylation. Cell Metabolism. 20: 448-57. PMID 25066056 DOI: 10.1016/j.cmet.2014.06.016  0.44
2014 Mehra VC, Jackson E, Zhang XM, Jiang XC, Dobrucki LW, Yu J, Bernatchez P, Sinusas AJ, Shulman GI, Sessa WC, Yarovinsky TO, Bender JR. Ceramide-activated phosphatase mediates fatty acid-induced endothelial VEGF resistance and impaired angiogenesis. The American Journal of Pathology. 184: 1562-76. PMID 24606881 DOI: 10.1016/j.ajpath.2014.01.009  0.44
2014 Lee MY, Skoura A, Park EJ, Landskroner-Eiger S, Jozsef L, Luciano AK, Murata T, Pasula S, Dong Y, Bouaouina M, Calderwood DA, Ferguson SM, De Camilli P, Sessa WC. Dynamin 2 regulation of integrin endocytosis, but not VEGF signaling, is crucial for developmental angiogenesis. Development (Cambridge, England). 141: 1465-72. PMID 24598168 DOI: 10.1242/dev.104539  0.44
2014 Jozsef L, Tashiro K, Kuo A, Park EJ, Skoura A, Albinsson S, Rivera-Molina F, Harrison KD, Iwakiri Y, Toomre D, Sessa WC. Reticulon 4 is necessary for endoplasmic reticulum tubulation, STIM1-Orai1 coupling, and store-operated calcium entry. The Journal of Biological Chemistry. 289: 9380-95. PMID 24558039 DOI: 10.1074/jbc.M114.548602  0.44
2014 Ju R, Zhuang ZW, Zhang J, Lanahan AA, Kyriakides T, Sessa WC, Simons M. Angiopoietin-2 secretion by endothelial cell exosomes: Regulation by the phosphatidylinositol 3-kinase (PI3K)/Akt/endothelial nitric oxide synthase (eNOS) and syndecan-4/syntenin pathways Journal of Biological Chemistry. 289: 510-519. PMID 24235146 DOI: 10.1074/jbc.M113.506899  0.44
2013 Kondo Y, Jadlowiec CC, Muto A, Yi T, Protack C, Collins MJ, Tellides G, Sessa WC, Dardik A. The Nogo-B-PirB axis controls macrophage-mediated vascular remodeling. Plos One. 8: e81019. PMID 24278366 DOI: 10.1371/journal.pone.0081019  0.44
2013 Di Lorenzo A, Lin MI, Murata T, Landskroner-Eiger S, Schleicher M, Kothiya M, Iwakiri Y, Yu J, Huang PL, Sessa WC. eNOS-derived nitric oxide regulates endothelial barrier function through VE-cadherin and Rho GTPases. Journal of Cell Science. 126: 5541-52. PMID 24046447 DOI: 10.1242/jcs.115972  0.88
2013 Jaba IM, Zhuang ZW, Li N, Jiang Y, Martin KA, Sinusas AJ, Papademetris X, Simons M, Sessa WC, Young LH, Tirziu D. NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growth. The Journal of Clinical Investigation. 123: 1718-31. PMID 23454748 DOI: 10.1172/JCI65112  0.44
2013 Kashiwagi S, Atochin DN, Li Q, Schleicher M, Pong T, Sessa WC, Huang PL. ENOS phosphorylation on serine 1176 affects insulin sensitivity and adiposity Biochemical and Biophysical Research Communications. 431: 284-290. PMID 23291238 DOI: 10.1016/j.bbrc.2012.12.110  0.44
2013 Goodwin JE, Feng Y, Velazquez H, Sessa WC. Endothelial glucocorticoid receptor is required for protection against sepsis. Proceedings of the National Academy of Sciences of the United States of America. 110: 306-11. PMID 23248291 DOI: 10.1073/pnas.1210200110  0.44
2013 Cho WK, Lee CM, Kang MJ, Huang Y, Giordano FJ, Lee PJ, Trow TK, Homer RJ, Sessa WC, Elias JA, Lee CG. IL-13 receptor α2-arginase 2 pathway mediates IL-13-induced pulmonary hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. 304: L112-24. PMID 23125252 DOI: 10.1152/ajplung.00101.2012  0.44
2012 Chick HE, Nowrouzi A, Fronza R, McDonald RA, Kane NM, Alba R, Delles C, Sessa WC, Schmidt M, Thrasher AJ, Baker AH. Integrase-deficient lentiviral vectors mediate efficient gene transfer to human vascular smooth muscle cells with minimal genotoxic risk. Human Gene Therapy. 23: 1247-57. PMID 22931362 DOI: 10.1089/hum.2012.042  0.44
2012 Zhang P, Huang A, Morales-Ruiz M, Starcher BC, Huang Y, Sessa WC, Niklason LE, Giordano FJ. Engineered zinc-finger proteins can compensate genetic haploinsufficiency by transcriptional activation of the wild-type allele: application to Willams-Beuren syndrome and supravalvular aortic stenosis. Human Gene Therapy. 23: 1186-99. PMID 22891920 DOI: 10.1089/hum.2011.201  0.44
2012 Marin EP, Derakhshan B, Lam TT, Davalos A, Sessa WC. Endothelial cell palmitoylproteomic identifies novel lipid-modified targets and potential substrates for protein acyl transferases. Circulation Research. 110: 1336-44. PMID 22496122 DOI: 10.1161/CIRCRESAHA.112.269514  0.44
2012 Tkachenko E, Tse D, Sideleva O, Deharvengt SJ, Luciano MR, Xu Y, McGarry CL, Chidlow J, Pilch PF, Sessa WC, Toomre DK, Stan RV. Caveolae, fenestrae and transendothelial channels retain PV1 on the surface of endothelial cells. Plos One. 7: e32655. PMID 22403691 DOI: 10.1371/journal.pone.0032655  0.44
2012 Sangwung P, Greco TM, Wang Y, Ischiropoulos H, Sessa WC, Iwakiri Y. Proteomic identification of S-nitrosylated Golgi proteins: new insights into endothelial cell regulation by eNOS-derived NO. Plos One. 7: e31564. PMID 22363674 DOI: 10.1371/journal.pone.0031564  0.44
2012 Yu J, Zhang Y, Zhang X, Rudic RD, Bauer PM, Altieri DC, Sessa WC. Endothelium derived nitric oxide synthase negatively regulates the PDGF-survivin pathway during flow-dependent vascular remodeling. Plos One. 7: e31495. PMID 22355372 DOI: 10.1371/journal.pone.0031495  0.44
2012 Zhang J, Modi Y, Yarovinsky T, Yu J, Collinge M, Kyriakides T, Zhu Y, Sessa WC, Pardi R, Bender JR. Macrophage β2 integrin-mediated, HuR-dependent stabilization of angiogenic factor-encoding mRNAs in inflammatory angiogenesis. The American Journal of Pathology. 180: 1751-60. PMID 22322302 DOI: 10.1016/j.ajpath.2011.12.025  0.4
2012 Zhang P, Huang A, Ferruzzi J, Mecham RP, Starcher BC, Tellides G, Humphrey JD, Giordano FJ, Niklason LE, Sessa WC. Inhibition of microRNA-29 enhances elastin levels in cells haploinsufficient for elastin and in bioengineered vessels--brief report. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 756-9. PMID 22095981 DOI: 10.1161/ATVBAHA.111.238113  0.44
2011 MacLauchlan S, Yu J, Parrish M, Asoulin TA, Schleicher M, Krady MM, Zeng J, Huang PL, Sessa WC, Kyriakides TR. Endothelial nitric oxide synthase controls the expression of the angiogenesis inhibitor thrombospondin 2. Proceedings of the National Academy of Sciences of the United States of America. 108: E1137-45. PMID 21949402 DOI: 10.1073/pnas.1104357108  0.44
2011 Bernatchez P, Sharma A, Bauer PM, Marin E, Sessa WC. A noninhibitory mutant of the caveolin-1 scaffolding domain enhances eNOS-derived NO synthesis and vasodilation in mice. The Journal of Clinical Investigation. 121: 3747-55. PMID 21804187 DOI: 10.1172/JCI44778  0.44
2011 Karuppiah K, Druhan LJ, Chen CA, Smith T, Zweier JL, Sessa WC, Cardounel AJ. Suppression of eNOS-derived superoxide by caveolin-1: a biopterin-dependent mechanism. American Journal of Physiology. Heart and Circulatory Physiology. 301: H903-11. PMID 21724868 DOI: 10.1152/ajpheart.00936.2010  0.44
2011 Sutendra G, Dromparis P, Wright P, Bonnet S, Haromy A, Hao Z, McMurtry MS, Michalak M, Vance JE, Sessa WC, Michelakis ED. The role of Nogo and the mitochondria-endoplasmic reticulum unit in pulmonary hypertension. Science Translational Medicine. 3: 88ra55. PMID 21697531 DOI: 10.1126/scitranslmed.3002194  0.44
2011 Harrison KD, Park EJ, Gao N, Kuo A, Rush JS, Waechter CJ, Lehrman MA, Sessa WC. Nogo-B receptor is necessary for cellular dolichol biosynthesis and protein N-glycosylation. The Embo Journal. 30: 2490-500. PMID 21572394 DOI: 10.1038/emboj.2011.147  0.44
2011 Albinsson S, Skoura A, Yu J, DiLorenzo A, Fernández-Hernando C, Offermanns S, Miano JM, Sessa WC. Smooth muscle miRNAs are critical for post-natal regulation of blood pressure and vascular function. Plos One. 6: e18869. PMID 21526127 DOI: 10.1371/journal.pone.0018869  0.44
2011 Muto A, Yi T, Harrison KD, Dávalos A, Fancher TT, Ziegler KR, Feigel A, Kondo Y, Nishibe T, Sessa WC, Dardik A. Eph-B4 prevents venous adaptive remodeling in the adult arterial environment. The Journal of Experimental Medicine. 208: 561-75. PMID 21339325 DOI: 10.1084/jem.20101854  0.44
2010 Wright PL, Yu J, Di YP, Homer RJ, Chupp G, Elias JA, Cohn L, Sessa WC. Epithelial reticulon 4B (Nogo-B) is an endogenous regulator of Th2-driven lung inflammation. The Journal of Experimental Medicine. 207: 2595-607. PMID 20975041 DOI: 10.1084/jem.20100786  0.44
2010 Marin EP, Moeckel G, Al-Lamki R, Bradley J, Yan Q, Wang T, Wright PL, Yu J, Sessa WC. Identification and regulation of reticulon 4B (Nogo-B) in renal tubular epithelial cells. The American Journal of Pathology. 177: 2765-73. PMID 20971739 DOI: 10.2353/ajpath.2010.100199  0.4
2010 Terasaka N, Westerterp M, Koetsveld J, Fernández-Hernando C, Yvan-Charvet L, Wang N, Sessa WC, Tall AR. ATP-binding cassette transporter G1 and high-density lipoprotein promote endothelial NO synthesis through a decrease in the interaction of caveolin-1 and endothelial NO synthase. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 2219-25. PMID 20798376 DOI: 10.1161/ATVBAHA.110.213215  0.44
2010 Lazorchak AS, Liu D, Facchinetti V, Di Lorenzo A, Sessa WC, Schatz DG, Su B. Sin1-mTORC2 suppresses rag and il7r gene expression through Akt2 in B cells. Molecular Cell. 39: 433-43. PMID 20705244 DOI: 10.1016/j.molcel.2010.07.031  0.44
2010 Zheng X, Xu C, Di Lorenzo A, Kleaveland B, Zou Z, Seiler C, Chen M, Cheng L, Xiao J, He J, Pack MA, Sessa WC, Kahn ML. CCM3 signaling through sterile 20-like kinases plays an essential role during zebrafish cardiovascular development and cerebral cavernous malformations. The Journal of Clinical Investigation. 120: 2795-804. PMID 20592472 DOI: 10.1172/JCI39679  0.44
2010 Dávalos A, Fernández-Hernando C, Sowa G, Derakhshan B, Lin MI, Lee JY, Zhao H, Luo R, Colangelo C, Sessa WC. Quantitative proteomics of caveolin-1-regulated proteins: characterization of polymerase i and transcript release factor/CAVIN-1 IN endothelial cells. Molecular & Cellular Proteomics : McP. 9: 2109-24. PMID 20585024 DOI: 10.1074/mcp.M110.001289  0.88
2010 Fernández-Hernando C, Yu J, Dávalos A, Prendergast J, Sessa WC. Endothelial-specific overexpression of caveolin-1 accelerates atherosclerosis in apolipoprotein E-deficient mice. The American Journal of Pathology. 177: 998-1003. PMID 20581061 DOI: 10.2353/ajpath.2010.091287  0.4
2010 Albinsson S, Suarez Y, Skoura A, Offermanns S, Miano JM, Sessa WC. MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 1118-26. PMID 20378849 DOI: 10.1161/ATVBAHA.109.200873  0.44
2009 Yu J, Fernández-Hernando C, Suarez Y, Schleicher M, Hao Z, Wright PL, DiLorenzo A, Kyriakides TR, Sessa WC. Reticulon 4B (Nogo-B) is necessary for macrophage infiltration and tissue repair. Proceedings of the National Academy of Sciences of the United States of America. 106: 17511-6. PMID 19805174 DOI: 10.1073/pnas.0907359106  0.44
2009 Harrison KD, Miao RQ, Fernandez-Hernándo C, Suárez Y, Dávalos A, Sessa WC. Nogo-B receptor stabilizes Niemann-Pick type C2 protein and regulates intracellular cholesterol trafficking. Cell Metabolism. 10: 208-18. PMID 19723497 DOI: 10.1016/j.cmet.2009.07.003  0.44
2009 Schleicher M, Yu J, Murata T, Derakhshan B, Atochin D, Qian L, Kashiwagi S, Di Lorenzo A, Harrison KD, Huang PL, Sessa WC. The Akt1-eNOS axis illustrates the specificity of kinase-substrate relationships in vivo Science Signaling. 2: ra41. PMID 19654415 DOI: 10.1126/scisignal.2000343  0.44
2009 Dobrucki LW, Dione DP, Kalinowski L, Dione D, Mendizabal M, Yu J, Papademetris X, Sessa WC, Sinusas AJ. Serial noninvasive targeted imaging of peripheral angiogenesis: validation and application of a semiautomated quantitative approach. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 50: 1356-63. PMID 19617325 DOI: 10.2967/jnumed.108.060822  0.44
2009 Fernández-Hernando C, Yu J, Suárez Y, Rahner C, Dávalos A, Lasunción MA, Sessa WC. Genetic evidence supporting a critical role of endothelial caveolin-1 during the progression of atherosclerosis. Cell Metabolism. 10: 48-54. PMID 19583953 DOI: 10.1016/j.cmet.2009.06.003  0.4
2009 Bernatchez PN, Sharma A, Kodaman P, Sessa WC. Myoferlin is critical for endocytosis in endothelial cells. American Journal of Physiology. Cell Physiology. 297: C484-92. PMID 19494235 DOI: 10.1152/ajpcell.00498.2008  0.44
2009 Chidlow JH, Greer JJ, Anthoni C, Bernatchez P, Fernandez-Hernando C, Fernadez-Hernando C, Bruce M, Abdelbaqi M, Shukla D, Granger DN, Sessa WC, Kevil CG. Endothelial caveolin-1 regulates pathologic angiogenesis in a mouse model of colitis. Gastroenterology. 136: 575-84.e2. PMID 19111727 DOI: 10.1053/j.gastro.2008.10.085  0.44
2008 Murata T, Lin MI, Aritake K, Matsumoto S, Narumiya S, Ozaki H, Urade Y, Hori M, Sessa WC. Role of prostaglandin D2 receptor DP as a suppressor of tumor hyperpermeability and angiogenesis in vivo. Proceedings of the National Academy of Sciences of the United States of America. 105: 20009-14. PMID 19060214 DOI: 10.1073/pnas.0805171105  0.44
2008 Kritz AB, Yu J, Wright PL, Wan S, George SJ, Halliday C, Kang N, Sessa WC, Baker AH. In vivo modulation of Nogo-B attenuates neointima formation. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1798-804. PMID 18781142 DOI: 10.1038/mt.2008.188  0.4
2008 Suárez Y, Fernández-Hernando C, Yu J, Gerber SA, Harrison KD, Pober JS, Iruela-Arispe ML, Merkenschlager M, Sessa WC. Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis. Proceedings of the National Academy of Sciences of the United States of America. 105: 14082-7. PMID 18779589 DOI: 10.1073/pnas.0804597105  0.44
2008 Derakhshan B, Harrison KD, Miao QR, Sessa WC. Chapter 1 Approaches for Studying Angiogenesis-Related Signal Transduction Methods in Enzymology. 443: 1-23. PMID 18772008 DOI: 10.1016/S0076-6879(08)02001-6  0.44
2008 Krady MM, Zeng J, Yu J, MacLauchlan S, Skokos EA, Tian W, Bornstein P, Sessa WC, Kyriakides TR. Thrombospondin-2 modulates extracellular matrix remodeling during physiological angiogenesis. The American Journal of Pathology. 173: 879-91. PMID 18688033 DOI: 10.2353/ajpath.2008.080128  0.44
2008 Kashiwagi S, Tsukada K, Xu L, Miyazaki J, Kozin SV, Tyrrell JA, Sessa WC, Gerweck LE, Jain RK, Fukumura D. Perivascular nitric oxide gradients normalize tumor vasculature. Nature Medicine. 14: 255-7. PMID 18278052 DOI: 10.1038/nm1730  0.44
2008 Tourkina E, Richard M, Gööz P, Bonner M, Pannu J, Harley R, Bernatchez PN, Sessa WC, Silver RM, Hoffman S. Antifibrotic properties of caveolin-1 scaffolding domain in vitro and in vivo. American Journal of Physiology. Lung Cellular and Molecular Physiology. 294: L843-61. PMID 18203815 DOI: 10.1152/ajplung.00295.2007  0.44
2008 Schleicher M, Shepherd BR, Suarez Y, Fernandez-Hernando C, Yu J, Pan Y, Acevedo LM, Shadel GS, Sessa WC. Prohibitin-1 maintains the angiogenic capacity of endothelial cells by regulating mitochondrial function and senescence. The Journal of Cell Biology. 180: 101-12. PMID 18195103 DOI: 10.1083/jcb.200706072  0.44
2008 Miao RQ, Fontana J, Fulton D, Lin MI, Harrison KD, Sessa WC. Dominant-negative Hsp90 reduces VEGF-stimulated nitric oxide release and migration in endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 105-11. PMID 17975117 DOI: 10.1161/ATVBAHA.107.155499  0.44
2007 Fernández-Hernando C, Ackah E, Yu J, Suárez Y, Murata T, Iwakiri Y, Prendergast J, Miao RQ, Birnbaum MJ, Sessa WC. Loss of Akt1 leads to severe atherosclerosis and occlusive coronary artery disease. Cell Metabolism. 6: 446-57. PMID 18054314 DOI: 10.1016/j.cmet.2007.10.007  0.44
2007 Li L, Hisamoto K, Kim KH, Haynes MP, Bauer PM, Sanjay A, Collinge M, Baron R, Sessa WC, Bender JR. Variant estrogen receptor-c-Src molecular interdependence and c-Src structural requirements for endothelial NO synthase activation. Proceedings of the National Academy of Sciences of the United States of America. 104: 16468-73. PMID 17921256 DOI: 10.1073/pnas.0704315104  0.44
2007 Pober JS, Sessa WC. Evolving functions of endothelial cells in inflammation. Nature Reviews. Immunology. 7: 803-15. PMID 17893694 DOI: 10.1038/nri2171  0.44
2007 Murata T, Lin MI, Huang Y, Yu J, Bauer PM, Giordano FJ, Sessa WC. Reexpression of caveolin-1 in endothelium rescues the vascular, cardiac, and pulmonary defects in global caveolin-1 knockout mice. The Journal of Experimental Medicine. 204: 2373-82. PMID 17893196 DOI: 10.1084/jem.20062340  0.44
2007 Bernatchez PN, Acevedo L, Fernandez-Hernando C, Murata T, Chalouni C, Kim J, Erdjument-Bromage H, Shah V, Gratton JP, McNally EM, Tempst P, Sessa WC. Myoferlin regulates vascular endothelial growth factor receptor-2 stability and function. The Journal of Biological Chemistry. 282: 30745-53. PMID 17702744 DOI: 10.1074/jbc.M704798200  0.44
2007 Atochin DN, Wang A, Liu VW, Critchlow JD, Dantas AP, Looft-Wilson R, Murata T, Salomone S, Shin HK, Ayata C, Moskowitz MA, Michel T, Sessa WC, Huang PL. The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivo. The Journal of Clinical Investigation. 117: 1961-7. PMID 17557122 DOI: 10.1172/JCI29877  0.36
2007 Murata T, Lin MI, Stan RV, Bauer PM, Yu J, Sessa WC. Genetic evidence supporting caveolae microdomain regulation of calcium entry in endothelial cells. The Journal of Biological Chemistry. 282: 16631-43. PMID 17416589 DOI: 10.1074/jbc.M607948200  0.44
2007 Suárez Y, Fernández-Hernando C, Pober JS, Sessa WC. Dicer dependent microRNAs regulate gene expression and functions in human endothelial cells. Circulation Research. 100: 1164-73. PMID 17379831 DOI: 10.1161/01.RES.0000265065.26744.17  0.44
2007 Lin MI, Yu J, Murata T, Sessa WC. Caveolin-1-deficient mice have increased tumor microvascular permeability, angiogenesis, and growth. Cancer Research. 67: 2849-56. PMID 17363608 DOI: 10.1158/0008-5472.CAN-06-4082  0.88
2007 Zhang H, Luo Y, Zhang W, He Y, Dai S, Zhang R, Huang Y, Bernatchez P, Giordano FJ, Shadel G, Sessa WC, Min W. Endothelial-specific expression of mitochondrial thioredoxin improves endothelial cell function and reduces atherosclerotic lesions. The American Journal of Pathology. 170: 1108-20. PMID 17322393 DOI: 10.2353/ajpath.2007.060960  0.44
2007 Pyriochou A, Zhou Z, Koika V, Petrou C, Cordopatis P, Sessa WC, Papapetropoulos A. The phosphodiesterase 5 inhibitor sildenafil stimulates angiogenesis through a protein kinase G/MAPK pathway. Journal of Cellular Physiology. 211: 197-204. PMID 17226792 DOI: 10.1002/jcp.20929  0.44
2006 Luo D, Luo Y, He Y, Zhang H, Zhang R, Li X, Dobrucki WL, Sinusas AJ, Sessa WC, Min W. Differential functions of tumor necrosis factor receptor 1 and 2 signaling in ischemia-mediated arteriogenesis and angiogenesis. The American Journal of Pathology. 169: 1886-98. PMID 17071609 DOI: 10.2353/ajpath.2006.060603  0.44
2006 Lin MI, Sessa WC. Vascular endothelial growth factor signaling to endothelial nitric oxide synthase: more than a FLeeTing moment. Circulation Research. 99: 666-8. PMID 17008595 DOI: 10.1161/01.RES.0000245430.24075.a4  0.88
2006 He Y, Luo Y, Tang S, Rajantie I, Salven P, Heil M, Zhang R, Luo D, Li X, Chi H, Yu J, Carmeliet P, Schaper W, Sinusas AJ, Sessa WC, et al. Critical function of Bmx/Etk in ischemia-mediated arteriogenesis and angiogenesis Journal of Clinical Investigation. 116: 2344-2355. PMID 16932810 DOI: 10.1172/JCI28123  0.44
2006 Phung TL, Ziv K, Dabydeen D, Eyiah-Mensah G, Riveros M, Perruzzi C, Sun J, Monahan-Earley RA, Shiojima I, Nagy JA, Lin MI, Walsh K, Dvorak AM, Briscoe DM, Neeman M, ... Sessa WC, et al. Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin Cancer Cell. 10: 159-170. PMID 16904613 DOI: 10.1016/j.ccr.2006.07.003  0.44
2006 Fernández-Hernando C, Fukata M, Bernatchez PN, Fukata Y, Lin MI, Bredt DS, Sessa WC. Identification of Golgi-localized acyl transferases that palmitoylate and regulate endothelial nitric oxide synthase. The Journal of Cell Biology. 174: 369-77. PMID 16864653 DOI: 10.1083/jcb.200601051  0.44
2006 Miao RQ, Gao Y, Harrison KD, Prendergast J, Acevedo LM, Yu J, Hu F, Strittmatter SM, Sessa WC. Identification of a receptor necessary for Nogo-B stimulated chemotaxis and morphogenesis of endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 10997-1002. PMID 16835300 DOI: 10.1073/pnas.0602427103  0.44
2006 Bhandari V, Choo-Wing R, Chapoval SP, Lee CG, Tang C, Kim YK, Ma B, Baluk P, Lin MI, McDonald DM, Homer RJ, Sessa WC, Elias JA. Essential role of nitric oxide in VEGF-induced, asthma-like angiogenic, inflammatory, mucus, and physiologic responses in the lung. Proceedings of the National Academy of Sciences of the United States of America. 103: 11021-6. PMID 16832062 DOI: 10.1073/pnas.0601057103  0.44
2006 Yu J, Bergaya S, Murata T, Alp IF, Bauer MP, Lin MI, Drab M, Kurzchalia TV, Stan RV, Sessa WC. Direct evidence for the role of caveolin-1 and caveolae in mechanotransduction and remodeling of blood vessels. The Journal of Clinical Investigation. 116: 1284-91. PMID 16670769 DOI: 10.1172/JCI27100  0.88
2006 Yu J, Lei L, Liang Y, Hinh L, Hickey RP, Huang Y, Liu D, Yeh JL, Rebar E, Case C, Spratt K, Sessa WC, Giordano FJ. An engineered VEGF-activating zinc finger protein transcription factor improves blood flow and limb salvage in advanced-age mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 479-81. PMID 16423874 DOI: 10.1096/fj.04-3670fje  0.4
2005 Ackah E, Yu J, Zoellner S, Iwakiri Y, Skurk C, Shibata R, Ouchi N, Easton RM, Galasso G, Birnbaum MJ, Walsh K, Sessa WC. Akt1/protein kinase Balpha is critical for ischemic and VEGF-mediated angiogenesis. The Journal of Clinical Investigation. 115: 2119-27. PMID 16075056 DOI: 10.1172/JCI24726  0.44
2005 Yu J, deMuinck ED, Zhuang Z, Drinane M, Kauser K, Rubanyi GM, Qian HS, Murata T, Escalante B, Sessa WC. Endothelial nitric oxide synthase is critical for ischemic remodeling, mural cell recruitment, and blood flow reserve. Proceedings of the National Academy of Sciences of the United States of America. 102: 10999-1004. PMID 16043715 DOI: 10.1073/pnas.0501444102  0.4
2005 Papapetropoulos A, Zhou Z, Gerassimou C, Yetik G, Venema RC, Roussos C, Sessa WC, Catravas JD. Interaction between the 90-kDa heat shock protein and soluble guanylyl cyclase: physiological significance and mapping of the domains mediating binding. Molecular Pharmacology. 68: 1133-41. PMID 16024662 DOI: 10.1124/mol.105.012682  0.32
2004 Lin MI, Sessa WC. Antiangiogenic therapy: creating a unique "window" of opportunity. Cancer Cell. 6: 529-31. PMID 15607955 DOI: 10.1016/j.ccr.2004.12.003  0.88
2004 Hagendoorn J, Padera TP, Kashiwagi S, Isaka N, Noda F, Lin MI, Huang PL, Sessa WC, Fukumura D, Jain RK. Endothelial nitric oxide synthase regulates microlymphatic flow via collecting lymphatics. Circulation Research. 95: 204-9. PMID 15192027 DOI: 10.1161/01.RES.0000135549.72828.24  0.88
2004 Bucci M, Roviezzo F, Brancaleone V, Lin MI, Di Lorenzo A, Cicala C, Pinto A, Sessa WC, Farneti S, Fiorucci S, Cirino G. Diabetic mouse angiopathy is linked to progressive sympathetic receptor deletion coupled to an enhanced caveolin-1 expression. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 721-6. PMID 14962949 DOI: 10.1161/01.ATV.0000122362.44628.09  0.88
2004 Papapetropoulos A, Fulton D, Lin MI, Fontana J, McCabe TJ, Zoellner S, García-Cardeña G, Zhou Z, Gratton JP, Sessa WC. Vanadate is a potent activator of endothelial nitric-oxide synthase: evidence for the role of the serine/threonine kinase Akt and the 90-kDa heat shock protein. Molecular Pharmacology. 65: 407-15. PMID 14742683 DOI: 10.1124/mol.65.2.407  0.88
2004 Ou J, Fontana JT, Ou Z, Jones DW, Ackerman AW, Oldham KT, Yu J, Sessa WC, Pritchard KA. Heat shock protein 90 and tyrosine kinase regulate eNOS NO* generation but not NO* bioactivity. American Journal of Physiology. Heart and Circulatory Physiology. 286: H561-9. PMID 14551044 DOI: 10.1152/ajpheart.00736.2003  0.44
2003 Lin MI, Fulton D, Babbitt R, Fleming I, Busse R, Pritchard KA, Sessa WC. Phosphorylation of threonine 497 in endothelial nitric-oxide synthase coordinates the coupling of L-arginine metabolism to efficient nitric oxide production. The Journal of Biological Chemistry. 278: 44719-26. PMID 12952971 DOI: 10.1074/jbc.M302836200  0.88
2003 Gratton JP, Lin MI, Yu J, Weiss ED, Jiang ZL, Fairchild TA, Iwakiri Y, Groszmann R, Claffey KP, Cheng YC, Sessa WC. Selective inhibition of tumor microvascular permeability by cavtratin blocks tumor progression in mice. Cancer Cell. 4: 31-9. PMID 12892711  0.88
2002 Napoli C, Ackah E, De Nigris F, Del Soldato P, D'Armiento FP, Crimi E, Condorelli M, Sessa WC. Chronic treatment with nitric oxide-releasing aspirin reduces plasma low-density lipoprotein oxidation and oxidative stress, arterial oxidation-specific epitopes, and atherogenesis in hypercholesterolemic mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 12467-70. PMID 12209007 DOI: 10.1073/pnas.192244499  0.32
2002 Yu J, Rudic RD, Sessa WC. Nitric oxide-releasing aspirin decreases vascular injury by reducing inflammation and promoting apoptosis. Laboratory Investigation; a Journal of Technical Methods and Pathology. 82: 825-32. PMID 12118084  0.76
2002 Scotland RS, Morales-Ruiz M, Chen Y, Yu J, Rudic RD, Fulton D, Gratton JP, Sessa WC. Functional reconstitution of endothelial nitric oxide synthase reveals the importance of serine 1179 in endothelium-dependent vasomotion. Circulation Research. 90: 904-10. PMID 11988492  0.76
2001 Pritchard KA, Ackerman AW, Gross ER, Stepp DW, Shi Y, Fontana JT, Baker JE, Sessa WC. Heat shock protein 90 mediates the balance of nitric oxide and superoxide anion from endothelial nitric-oxide synthase. The Journal of Biological Chemistry. 276: 17621-4. PMID 11278264 DOI: 10.1074/jbc.C100084200  0.44
2000 Bucci M, Gratton JP, Rudic RD, Acevedo L, Roviezzo F, Cirino G, Sessa WC. In vivo delivery of the caveolin-1 scaffolding domain inhibits nitric oxide synthesis and reduces inflammation. Nature Medicine. 6: 1362-7. PMID 11100121 DOI: 10.1038/82176  0.76
2000 Luo Z, Fujio Y, Kureishi Y, Rudic RD, Daumerie G, Fulton D, Sessa WC, Walsh K. Acute modulation of endothelial Akt/PKB activity alters nitric oxide-dependent vasomotor activity in vivo. The Journal of Clinical Investigation. 106: 493-9. PMID 10953024 DOI: 10.1172/JCI9419  0.76
2000 Rudic RD, Bucci M, Fulton D, Segal SS, Sessa WC. Temporal events underlying arterial remodeling after chronic flow reduction in mice: correlation of structural changes with a deficit in basal nitric oxide synthesis. Circulation Research. 86: 1160-6. PMID 10850968  0.44
1999 Papapetropoulos A, Rudic RD, Sessa WC. Molecular control of nitric oxide synthases in the cardiovascular system. Cardiovascular Research. 43: 509-20. PMID 10690323  0.76
1999 Rudic RD, Sessa WC. Nitric oxide in endothelial dysfunction and vascular remodeling: clinical correlates and experimental links. American Journal of Human Genetics. 64: 673-7. PMID 10052999 DOI: 10.1086/302304  0.76
1998 Rudic RD, Shesely EG, Maeda N, Smithies O, Segal SS, Sessa WC. Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling. The Journal of Clinical Investigation. 101: 731-6. PMID 9466966 DOI: 10.1172/JCI1699  0.44
1997 Papapetropoulos A, Desai KM, Rudic RD, Mayer B, Zhang R, Ruiz-Torres MP, García-Cardeña G, Madri JA, Sessa WC. Nitric oxide synthase inhibitors attenuate transforming-growth-factor-beta 1-stimulated capillary organization in vitro. The American Journal of Pathology. 150: 1835-44. PMID 9137106  0.44
1991 Pagano PJ, Lin L, Sessa WC, Nasjletti A. Arachidonic acid elicits endothelium-dependent release from the rabbit aorta of a constrictor prostanoid resembling prostaglandin endoperoxides. Circulation Research. 69: 396-405. PMID 1907227  1
1990 Sessa WC, Nasjletti A. Dexamethasone selectively attenuates prostanoid-induced vasoconstrictor responses in vitro. Circulation Research. 66: 383-8. PMID 2297809  1
1990 Sessa WC, Halushka PV, Okwu A, Nasjletti A. Characterization of the vascular thromboxane A2/prostaglandin endoperoxide receptor in rabbit aorta. Regulation by dexamethasone. Circulation Research. 67: 1562-9. PMID 2147131  1
1990 Sessa WC, Lin L, Nasjletti A. Reciprocal effects of dexamethasone on vasodilatory responses to arachidonic acid and prostanoids in the isolated perfused rabbit kidney. Hypertension (Dallas, Tex. : 1979). 15: I93-6. PMID 2105268  1
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