Year |
Citation |
Score |
2024 |
Boutagy NE, Gamez-Mendez A, Fowler JW, Zhang H, Chaube BK, Esplugues E, Lee S, Horikami D, Zhang J, Citrin KM, Singh AK, Coon BG, Suarez Y, Fernandez-Hernando C, Sessa WC. Dynamic metabolism of endothelial triglycerides protects against atherosclerosis in mice. The Journal of Clinical Investigation. PMID 38175710 DOI: 10.1172/JCI170453 |
0.355 |
|
2023 |
Nguyen TD, Rahman NT, Sessa WC, Lee MY. Endothelial nitric oxide synthase (eNOS) S1176 phosphorylation status governs atherosclerotic lesion formation. Frontiers in Cardiovascular Medicine. 10: 1279868. PMID 38034389 DOI: 10.3389/fcvm.2023.1279868 |
0.385 |
|
2021 |
Ribera J, Portolés I, Córdoba-Jover B, Rodríguez-Vita J, Casals G, González-de la Presa B, Graupera M, Solsona-Vilarrasa E, Garcia-Ruiz C, Fernández-Checa JC, Soria G, Tudela R, Esteve-Codina A, Espadas G, Sabidó E, ... ... Sessa WC, et al. The loss of DHX15 impairs endothelial energy metabolism, lymphatic drainage and tumor metastasis in mice. Communications Biology. 4: 1192. PMID 34654883 DOI: 10.1038/s42003-021-02722-w |
0.36 |
|
2021 |
Park H, Furtado J, Poulet M, Chung M, Yun S, Lee S, Sessa WC, Franco CA, Schwartz MA, Eichmann A. Defective Flow-Migration Coupling Causes Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia. Circulation. PMID 34182767 DOI: 10.1161/CIRCULATIONAHA.120.053047 |
0.338 |
|
2021 |
Bernatchez PN, Tao B, Bradshaw RA, Eveleth D, Sessa WC. Characterization of a Novel Caveolin Modulator That Reduces Vascular Permeability and Ocular Inflammation. Translational Vision Science & Technology. 10: 21. PMID 34111267 DOI: 10.1167/tvst.10.6.21 |
0.303 |
|
2021 |
Ninchoji T, Love DT, Smith RO, Hedlund M, Vestweber D, Sessa WC, Claesson-Welsh L. eNOS-induced vascular barrier disruption in retinopathy by c-Src activation and tyrosine phosphorylation of VE-cadherin. Elife. 10. PMID 33908348 DOI: 10.7554/eLife.64944 |
0.338 |
|
2020 |
Tao B, Kraehling JR, Ghaffari S, Ramirez CM, Lee S, Fowler JW, Lee WL, Fernandez-Hernando C, Eichmann A, Sessa WC. BMP-9 and LDL crosstalk regulates ALK-1 endocytosis and LDL transcytosis in endothelial cells. The Journal of Biological Chemistry. 295: 18179-18188. PMID 33453825 DOI: 10.1074/jbc.RA120.015680 |
0.346 |
|
2020 |
Tao B, Kraehling JR, Ghaffari S, Ramirez CM, Lee S, Fowler JW, Lee WL, Fernandez-Hernando C, Eichmann A, Sessa WC. BMP-9 and LDL crosstalk regulates ALK-1 endocytosis and LDL transcytosis in endothelial cells. The Journal of Biological Chemistry. PMID 33097593 DOI: 10.1074/jbc.RA120.015680 |
0.348 |
|
2020 |
Boutagy NE, Fowler JW, Sessa WC. A Vectorial, ER-Mitochondria Link to Energy Homeostasis in the Vascular Endothelium. Cell Metabolism. 32: 150-152. PMID 32755606 DOI: 10.1016/J.Cmet.2020.07.010 |
0.333 |
|
2020 |
Zhang X, Ramírez CM, Aryal B, Madrigal-Matute J, Liu X, Diaz A, Torrecilla-Parra M, Suárez Y, Cuervo AM, Sessa WC, Fernández-Hernando C. Cav-1 (Caveolin-1) Deficiency Increases Autophagy in the Endothelium and Attenuates Vascular Inflammation and Atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120314291. PMID 32349535 DOI: 10.1161/Atvbaha.120.314291 |
0.433 |
|
2020 |
Garcia V, Park EJ, Siragusa M, Frohlich F, Haque MM, Pascale JV, Heberlein KR, Isakson BE, Stuehr DJ, Sessa WC. Unbiased proteomics identifies plasminogen activator inhibitor-1 as a negative regulator of endothelial nitric oxide synthase. Proceedings of the National Academy of Sciences of the United States of America. PMID 32300005 DOI: 10.1073/Pnas.1918761117 |
0.49 |
|
2020 |
Zhou H, Mehta S, Srivastava SP, Grabinska K, Zhang X, Wong C, Hedayat A, Perrotta P, Fernández-Hernando C, Sessa WC, Goodwin JE. Endothelial cell-glucocorticoid receptor interactions and regulation of Wnt signaling. Jci Insight. 5. PMID 32051336 DOI: 10.1172/Jci.Insight.131384 |
0.442 |
|
2019 |
Looft-Wilson RC, Billig JE, Sessa WC. Shear Stress Attenuates Inward Remodeling in Cultured Mouse Thoracodorsal Arteries in an eNOS-Dependent, but Not Hemodynamic Manner, and Increases Cx37 Expression. Journal of Vascular Research. 1-12. PMID 31574503 DOI: 10.1159/000502690 |
0.321 |
|
2019 |
RamÍrez CM, Zhang X, Bandyopadhyay C, Rotllan N, Sugiyama MG, Aryal B, Liu X, He S, Kraehling JR, Ulrich V, Lin CS, Velazquez H, Lasunción MA, Li G, Suárez Y, ... ... Sessa WC, et al. Caveolin-1 Regulates Atherogenesis by Attenuating LDL Transcytosis and Vascular Inflammation Independent of Endothelial Nitric Oxide Synthase Activation. Circulation. PMID 31154825 DOI: 10.1161/Circulationaha.118.038571 |
0.461 |
|
2019 |
Hashimoto T, Isaji T, Hu H, Yamamoto K, Bai H, Santana JM, Kuo A, Kuwahara G, Foster TR, Hanisch JJ, Yatsula BA, Sessa WC, Hoshina K, Dardik A. Stimulation of Caveolin-1 Signaling Improves Arteriovenous Fistula Patency. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA119312417. PMID 30786746 DOI: 10.1161/Atvbaha.119.312417 |
0.419 |
|
2018 |
Garcia V, Sessa WC. Endothelial Nitric Oxide Synthase (eNOS): Perspective and Recent Developments. British Journal of Pharmacology. PMID 30341769 DOI: 10.1111/Bph.14522 |
0.482 |
|
2018 |
Zhang X, Sessa WC, Fernández-Hernando C. Endothelial Transcytosis of Lipoproteins in Atherosclerosis. Frontiers in Cardiovascular Medicine. 5: 130. PMID 30320124 DOI: 10.3389/Fcvm.2018.00130 |
0.383 |
|
2018 |
Zhang F, Zarkada G, Han J, Li J, Dubrac A, Ola R, Genet G, Boyé K, Michon P, Künzel SE, Camporez JP, Singh AK, Fong GH, Simons M, Tso P, ... ... Sessa WC, et al. Lacteal junction zippering protects against diet-induced obesity. Science (New York, N.Y.). 361: 599-603. PMID 30093598 DOI: 10.1126/Science.Aap9331 |
0.386 |
|
2018 |
Ola R, Künzel SH, Zhang F, Genet G, Chakraborty R, Pibouin-Fragner L, Martin K, Sessa W, Dubrac A, Eichmann A. SMAD4 Prevents Flow Induced Arterial-Venous Malformations by Inhibiting Casein Kinase 2. Circulation. PMID 29976569 DOI: 10.1161/Circulationaha.118.033842 |
0.457 |
|
2018 |
Luciano AK, Zhou W, Santana JM, Kyriakides C, Velazquez H, Sessa WC. CLOCK phosphorylation by AKT regulates its nuclear accumulation and circadian gene expression in peripheral tissues. The Journal of Biological Chemistry. PMID 29588368 DOI: 10.1074/Jbc.Ra117.000773 |
0.304 |
|
2018 |
Lee MY, Gamez-Mendez A, Zhang J, Zhuang Z, Vinyard DJ, Kraehling J, Velazquez H, Brudvig GW, Kyriakides TR, Simons M, Sessa WC. Endothelial Cell Autonomous Role of Akt1: Regulation of Vascular Tone and Ischemia-Induced Arteriogenesis. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 29449333 DOI: 10.1161/Atvbaha.118.310748 |
0.477 |
|
2017 |
Kuo A, Lee MY, Yang K, Gross RW, Sessa WC. Caveolin-1 regulates lipid droplet metabolism in endothelial cells via autocrine prostacyclin stimulated cAMP-mediated lipolysis. The Journal of Biological Chemistry. PMID 29203526 DOI: 10.1074/Jbc.Ra117.000980 |
0.413 |
|
2017 |
Protack CD, Foster TR, Hashimoto T, Yamamoto K, Lee MY, Kraehling JR, Bai H, Hu H, Isaji T, Santana JM, Wang M, Sessa WC, Dardik A. Eph-B4 regulates adaptive venous remodeling to improve arteriovenous fistula patency. Scientific Reports. 7: 15386. PMID 29133876 DOI: 10.1038/S41598-017-13071-2 |
0.373 |
|
2017 |
Jin Y, Xie Y, Ostriker AC, Zhang X, Liu R, Lee MY, Leslie KL, Tang W, Du J, Lee SH, Wang Y, Sessa WC, Hwa J, Yu J, Martin KA. Opposing Actions of AKT (Protein Kinase B) Isoforms in Vascular Smooth Muscle Injury and Therapeutic Response. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 29025710 DOI: 10.1161/Atvbaha.117.310053 |
0.427 |
|
2017 |
Jiang Y, Lin X, Tang Z, Lee C, Tian G, Du Y, Yin X, Ren X, Huang L, Ye Z, Chen W, Zhang F, Mi J, Gao Z, Wang S, ... ... Sessa WC, et al. Critical role of caveolin-1 in ocular neovascularization and multitargeted antiangiogenic effects of cavtratin via JNK. Proceedings of the National Academy of Sciences of the United States of America. PMID 28923916 DOI: 10.1073/Pnas.1706394114 |
0.468 |
|
2017 |
MacLauchlan SC, Calabro NE, Huang Y, Krishna M, Bancroft T, Sharma T, Yu J, Sessa WC, Giordano F, Kyriakides TR. HIF-1α represses the expression of the angiogenesis inhibitor thrombospondin-2. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 28789925 DOI: 10.1016/J.Matbio.2017.07.002 |
0.353 |
|
2017 |
Luciano AK, Santana JM, Velazquez H, Sessa WC. Akt1 Controls the Timing and Amplitude of Vascular Circadian Gene Expression. Journal of Biological Rhythms. 748730417704534. PMID 28452287 DOI: 10.1177/0748730417704534 |
0.369 |
|
2017 |
Kraehling JR, Sessa WC. Contemporary Approaches to Modulating the Nitric Oxide-cGMP Pathway in Cardiovascular Disease. Circulation Research. 120: 1174-1182. PMID 28360348 DOI: 10.1161/Circresaha.117.303776 |
0.479 |
|
2017 |
Kuo A, Lee MY, Sessa WC. Lipid Droplet Biogenesis and Function in the Endothelium. Circulation Research. PMID 28119423 DOI: 10.1161/Circresaha.116.310498 |
0.361 |
|
2016 |
Ola R, Dubrac A, Han J, Zhang F, Fang JS, Larrivée B, Lee M, Urarte AA, Kraehling JR, Genet G, Hirschi KK, Sessa WC, Canals FV, Graupera M, Yan M, et al. PI3 kinase inhibition improves vascular malformations in mouse models of hereditary haemorrhagic telangiectasia. Nature Communications. 7: 13650. PMID 27897192 DOI: 10.1038/Ncomms13650 |
0.463 |
|
2016 |
Kraehling JR, Chidlow JH, Rajagopal C, Sugiyama MG, Fowler JW, Lee MY, Zhang X, Ramírez CM, Park EJ, Tao B, Chen K, Kuruvilla L, Larriveé B, Folta-Stogniew E, Ola R, ... ... Sessa WC, et al. Genome-wide RNAi screen reveals ALK1 mediates LDL uptake and transcytosis in endothelial cells. Nature Communications. 7: 13516. PMID 27869117 DOI: 10.1038/Ncomms13516 |
0.411 |
|
2016 |
Park EJ, Grabińska KA, Guan Z, Sessa WC. NgBR is essential for endothelial cell glycosylation and vascular development. Embo Reports. PMID 26755743 DOI: 10.15252/Embr.201540789 |
0.483 |
|
2016 |
Marin EP, Jozsef L, Di Lorenzo A, Held KF, Luciano AK, Melendez J, Milstone LM, Velazquez H, Sessa WC. The Protein Acyl Transferase ZDHHC21 Modulates α1 Adrenergic Receptor Function and Regulates Hemodynamics. Arteriosclerosis, Thrombosis, and Vascular Biology. 36: 370-9. PMID 26715683 DOI: 10.1161/Atvbaha.115.306942 |
0.357 |
|
2015 |
Kraehling JR, Hao Z, Lee MY, Vinyard D, Velazquez H, Liu X, Stan RV, Brudvig G, Sessa WC. Uncoupling Caveolae from Intracellular Signaling In Vivo. Circulation Research. PMID 26602865 DOI: 10.1161/Circresaha.115.307767 |
0.429 |
|
2015 |
Chamorro-Jorganes A, Lee MY, Araldi E, Landskroner-Eiger S, Fernandez-Fuertes M, Sahraei M, Quiles Del Rey M, van Solingen C, Yu J, Fernandez-Hernando C, Sessa WC, Suarez Y. VEGF-Induced Expression of miR-17~92 Cluster in Endothelial Cells is Mediated by ERK/ELK1 Activation and Regulates Angiogenesis. Circulation Research. PMID 26472816 DOI: 10.1161/Circresaha.115.307408 |
0.409 |
|
2015 |
Landskroner-Eiger S, Qiu C, Perrotta P, Siragusa M, Lee MY, Ulrich V, Luciano AK, Zhuang ZW, Corti F, Simons M, Montgomery RL, Wu D, Yu J, Sessa WC. Endothelial miR-17∼92 cluster negatively regulates arteriogenesis via miRNA-19 repression of WNT signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 26417068 DOI: 10.1073/Pnas.1507094112 |
0.316 |
|
2015 |
Siragusa M, Fröhlich F, Park EJ, Schleicher M, Walther TC, Sessa WC. Stromal cell-derived factor 2 is critical for Hsp90-dependent eNOS activation. Science Signaling. 8: ra81. PMID 26286023 DOI: 10.1126/Scisignal.Aaa2819 |
0.514 |
|
2015 |
Kraehling JR, Sessa WC. Enhanced eNOS Activation as the Fountain of Youth for Vascular Disease: Is BPIFB4 What Ponce de León Was Looking For? Circulation Research. 117: 309-10. PMID 26227874 DOI: 10.1161/Circresaha.115.307020 |
0.303 |
|
2015 |
Xie Y, Jin Y, Merenick BL, Ding M, Fetalvero KM, Wagner RJ, Mai A, Gleim S, Tucker DF, Birnbaum MJ, Ballif BA, Luciano AK, Sessa WC, Rzucidlo EM, Powell RJ, et al. Phosphorylation of GATA-6 is required for vascular smooth muscle cell differentiation after mTORC1 inhibition. Science Signaling. 8: ra44. PMID 25969542 DOI: 10.1126/Scisignal.2005482 |
0.444 |
|
2015 |
Rotllan N, Wanschel AC, Fernández-Hernando A, Salerno AG, Offermanns S, Sessa WC, Fernández-Hernando C. Genetic Evidence Supports a Major Role for Akt1 in VSMCs During Atherogenesis. Circulation Research. 116: 1744-52. PMID 25868464 DOI: 10.1161/Circresaha.116.305895 |
0.435 |
|
2015 |
Goodwin JE, Zhang X, Rotllan N, Feng Y, Zhou H, Fernández-Hernando C, Yu J, Sessa WC. Endothelial glucocorticoid receptor suppresses atherogenesis--brief report. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 779-82. PMID 25810297 DOI: 10.1161/Atvbaha.114.304525 |
0.389 |
|
2015 |
Rotllan N, Chamorro-Jorganes A, Araldi E, Wanschel AC, Aryal B, Aranda JF, Goedeke L, Salerno AG, RamÃrez CM, Sessa WC, Suárez Y, Fernández-Hernando C. Hematopoietic Akt2 deficiency attenuates the progression of atherosclerosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 597-610. PMID 25392271 DOI: 10.1096/Fj.14-262097 |
0.366 |
|
2015 |
Bancroft T, Bouaouina M, Roberts S, Lee M, Calderwood DA, Schwartz M, Simons M, Sessa WC, Kyriakides TR. Up-regulation of thrombospondin-2 in Akt1-null mice contributes to compromised tissue repair due to abnormalities in fibroblast function. The Journal of Biological Chemistry. 290: 409-22. PMID 25389299 DOI: 10.1074/Jbc.M114.618421 |
0.413 |
|
2015 |
Pober JS, Sessa WC. Inflammation and the blood microvascular system. Cold Spring Harbor Perspectives in Biology. 7: a016345. PMID 25384307 DOI: 10.1101/Cshperspect.A016345 |
0.376 |
|
2014 |
Goodwin JE, Feng Y, Velazquez H, Zhou H, Sessa WC. Loss of the endothelial glucocorticoid receptor prevents the therapeutic protection afforded by dexamethasone after LPS. Plos One. 9: e108126. PMID 25299055 DOI: 10.1371/Journal.Pone.0108126 |
0.336 |
|
2014 |
Lee MY, Luciano AK, Ackah E, Rodriguez-Vita J, Bancroft TA, Eichmann A, Simons M, Kyriakides TR, Morales-Ruiz M, Sessa WC. Endothelial Akt1 mediates angiogenesis by phosphorylating multiple angiogenic substrates. Proceedings of the National Academy of Sciences of the United States of America. 111: 12865-70. PMID 25136137 DOI: 10.1073/Pnas.1408472111 |
0.825 |
|
2014 |
Park EJ, Grabi?ska KA, Guan Z, Stránecký V, Hartmannová H, Hoda?ová K, Barešová V, Sovová J, Jozsef L, Ondrušková N, Hansíková H, Honzík T, Zeman J, H?lková H, Wen R, ... ... Sessa WC, et al. Mutation of Nogo-B receptor, a subunit of cis-prenyltransferase, causes a congenital disorder of glycosylation. Cell Metabolism. 20: 448-57. PMID 25066056 DOI: 10.1016/J.Cmet.2014.06.016 |
0.311 |
|
2014 |
Mehra VC, Jackson E, Zhang XM, Jiang XC, Dobrucki LW, Yu J, Bernatchez P, Sinusas AJ, Shulman GI, Sessa WC, Yarovinsky TO, Bender JR. Ceramide-activated phosphatase mediates fatty acid-induced endothelial VEGF resistance and impaired angiogenesis. The American Journal of Pathology. 184: 1562-76. PMID 24606881 DOI: 10.1016/J.Ajpath.2014.01.009 |
0.486 |
|
2014 |
Lee MY, Skoura A, Park EJ, Landskroner-Eiger S, Jozsef L, Luciano AK, Murata T, Pasula S, Dong Y, Bouaouina M, Calderwood DA, Ferguson SM, De Camilli P, Sessa WC. Dynamin 2 regulation of integrin endocytosis, but not VEGF signaling, is crucial for developmental angiogenesis. Development (Cambridge, England). 141: 1465-72. PMID 24598168 DOI: 10.1242/Jcs.153080 |
0.468 |
|
2014 |
Jozsef L, Tashiro K, Kuo A, Park EJ, Skoura A, Albinsson S, Rivera-Molina F, Harrison KD, Iwakiri Y, Toomre D, Sessa WC. Reticulon 4 is necessary for endoplasmic reticulum tubulation, STIM1-Orai1 coupling, and store-operated calcium entry. The Journal of Biological Chemistry. 289: 9380-95. PMID 24558039 DOI: 10.1074/Jbc.M114.548602 |
0.732 |
|
2014 |
Ju R, Zhuang ZW, Zhang J, Lanahan AA, Kyriakides T, Sessa WC, Simons M. Angiopoietin-2 secretion by endothelial cell exosomes: Regulation by the phosphatidylinositol 3-kinase (PI3K)/Akt/endothelial nitric oxide synthase (eNOS) and syndecan-4/syntenin pathways Journal of Biological Chemistry. 289: 510-519. PMID 24235146 DOI: 10.1074/Jbc.M113.506899 |
0.516 |
|
2013 |
Kondo Y, Jadlowiec CC, Muto A, Yi T, Protack C, Collins MJ, Tellides G, Sessa WC, Dardik A. The Nogo-B-PirB axis controls macrophage-mediated vascular remodeling. Plos One. 8: e81019. PMID 24278366 DOI: 10.1371/Journal.Pone.0081019 |
0.447 |
|
2013 |
Di Lorenzo A, Lin MI, Murata T, Landskroner-Eiger S, Schleicher M, Kothiya M, Iwakiri Y, Yu J, Huang PL, Sessa WC. eNOS-derived nitric oxide regulates endothelial barrier function through VE-cadherin and Rho GTPases. Journal of Cell Science. 126: 5541-52. PMID 24046447 DOI: 10.1242/Jcs.115972 |
0.685 |
|
2013 |
Reese C, Dyer S, Perry B, Bonner M, Oates J, Hofbauer A, Sessa W, Bernatchez P, Visconti RP, Zhang J, Hatfield CM, Silver RM, Hoffman S, Tourkina E. Differential regulation of cell functions by CSD peptide subdomains. Respiratory Research. 14: 90. PMID 24011378 DOI: 10.1186/1465-9921-14-90 |
0.305 |
|
2013 |
Li Q, Atochin D, Kashiwagi S, Earle J, Wang A, Mandeville E, Hayakawa K, d'Uscio LV, Lo EH, Katusic Z, Sessa W, Huang PL. Deficient eNOS phosphorylation is a mechanism for diabetic vascular dysfunction contributing to increased stroke size. Stroke; a Journal of Cerebral Circulation. 44: 3183-8. PMID 23988642 DOI: 10.1161/Strokeaha.113.002073 |
0.386 |
|
2013 |
Huang Y, Di Lorenzo A, Jiang W, Cantalupo A, Sessa WC, Giordano FJ. Hypoxia-inducible factor-1α in vascular smooth muscle regulates blood pressure homeostasis through a peroxisome proliferator-activated receptor-γ-angiotensin II receptor type 1 axis. Hypertension. 62: 634-40. PMID 23918749 DOI: 10.1161/Hypertensionaha.111.00160 |
0.325 |
|
2013 |
Siragusa M, Sessa WC. Telmisartan exerts pleiotropic effects in endothelial cells and promotes endothelial cell quiescence and survival. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 1852-60. PMID 23702662 DOI: 10.1161/Atvbaha.112.300985 |
0.434 |
|
2013 |
Li W, Li Q, Qin L, Ali R, Qyang Y, Tassabehji M, Pober BR, Sessa WC, Giordano FJ, Tellides G. Rapamycin inhibits smooth muscle cell proliferation and obstructive arteriopathy attributable to elastin deficiency. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 1028-35. PMID 23493289 DOI: 10.1161/Atvbaha.112.300407 |
0.342 |
|
2013 |
Jaba IM, Zhuang ZW, Li N, Jiang Y, Martin KA, Sinusas AJ, Papademetris X, Simons M, Sessa WC, Young LH, Tirziu D. NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growth. The Journal of Clinical Investigation. 123: 1718-31. PMID 23454748 DOI: 10.1172/Jci65112 |
0.359 |
|
2013 |
Kashiwagi S, Atochin DN, Li Q, Schleicher M, Pong T, Sessa WC, Huang PL. ENOS phosphorylation on serine 1176 affects insulin sensitivity and adiposity Biochemical and Biophysical Research Communications. 431: 284-290. PMID 23291238 DOI: 10.1016/J.Bbrc.2012.12.110 |
0.369 |
|
2013 |
Goodwin JE, Feng Y, Velazquez H, Sessa WC. Endothelial glucocorticoid receptor is required for protection against sepsis. Proceedings of the National Academy of Sciences of the United States of America. 110: 306-11. PMID 23248291 DOI: 10.1073/Pnas.1210200110 |
0.447 |
|
2012 |
Sessa WC. A new approach to weight loss: just activate endothelial NO synthase! Circulation Research. 111: 1111-2. PMID 23065339 DOI: 10.1161/Circresaha.112.279794 |
0.446 |
|
2012 |
Chick HE, Nowrouzi A, Fronza R, McDonald RA, Kane NM, Alba R, Delles C, Sessa WC, Schmidt M, Thrasher AJ, Baker AH. Integrase-deficient lentiviral vectors mediate efficient gene transfer to human vascular smooth muscle cells with minimal genotoxic risk. Human Gene Therapy. 23: 1247-57. PMID 22931362 DOI: 10.1089/Hum.2012.042 |
0.345 |
|
2012 |
Zhang P, Huang A, Morales-Ruiz M, Starcher BC, Huang Y, Sessa WC, Niklason LE, Giordano FJ. Engineered zinc-finger proteins can compensate genetic haploinsufficiency by transcriptional activation of the wild-type allele: application to Willams-Beuren syndrome and supravalvular aortic stenosis. Human Gene Therapy. 23: 1186-99. PMID 22891920 DOI: 10.1089/Hum.2011.201 |
0.337 |
|
2012 |
Marin EP, Derakhshan B, Lam TT, Davalos A, Sessa WC. Endothelial cell palmitoylproteomic identifies novel lipid-modified targets and potential substrates for protein acyl transferases. Circulation Research. 110: 1336-44. PMID 22496122 DOI: 10.1161/Circresaha.112.269514 |
0.376 |
|
2012 |
Tkachenko E, Tse D, Sideleva O, Deharvengt SJ, Luciano MR, Xu Y, McGarry CL, Chidlow J, Pilch PF, Sessa WC, Toomre DK, Stan RV. Caveolae, fenestrae and transendothelial channels retain PV1 on the surface of endothelial cells. Plos One. 7: e32655. PMID 22403691 DOI: 10.1371/Journal.Pone.0032655 |
0.369 |
|
2012 |
Sangwung P, Greco TM, Wang Y, Ischiropoulos H, Sessa WC, Iwakiri Y. Proteomic identification of S-nitrosylated Golgi proteins: new insights into endothelial cell regulation by eNOS-derived NO. Plos One. 7: e31564. PMID 22363674 DOI: 10.1371/Journal.Pone.0031564 |
0.456 |
|
2012 |
Yu J, Zhang Y, Zhang X, Rudic RD, Bauer PM, Altieri DC, Sessa WC. Endothelium derived nitric oxide synthase negatively regulates the PDGF-survivin pathway during flow-dependent vascular remodeling. Plos One. 7: e31495. PMID 22355372 DOI: 10.1371/Journal.Pone.0031495 |
0.774 |
|
2012 |
Zhang J, Modi Y, Yarovinsky T, Yu J, Collinge M, Kyriakides T, Zhu Y, Sessa WC, Pardi R, Bender JR. Macrophage β2 integrin-mediated, HuR-dependent stabilization of angiogenic factor-encoding mRNAs in inflammatory angiogenesis. The American Journal of Pathology. 180: 1751-60. PMID 22322302 DOI: 10.1016/J.Ajpath.2011.12.025 |
0.364 |
|
2012 |
Förstermann U, Sessa WC. Nitric oxide synthases: regulation and function. European Heart Journal. 33: 829-37, 837a-837d. PMID 21890489 DOI: 10.1093/Eurheartj/Ehr304 |
0.459 |
|
2012 |
Collins M, Muto A, Feigel A, Protack C, Jadlowiec C, Sessa W, Dardik A. EphB4 Activates Endothelial Nitric Oxide Synthase in An Akt-dependent Mechanism to Regulate Vein Graft Adaptation Journal of Surgical Research. 172: 267. DOI: 10.1016/J.Jss.2011.11.869 |
0.453 |
|
2011 |
MacLauchlan S, Yu J, Parrish M, Asoulin TA, Schleicher M, Krady MM, Zeng J, Huang PL, Sessa WC, Kyriakides TR. Endothelial nitric oxide synthase controls the expression of the angiogenesis inhibitor thrombospondin 2. Proceedings of the National Academy of Sciences of the United States of America. 108: E1137-45. PMID 21949402 DOI: 10.1073/Pnas.1104357108 |
0.494 |
|
2011 |
Bernatchez P, Sharma A, Bauer PM, Marin E, Sessa WC. A noninhibitory mutant of the caveolin-1 scaffolding domain enhances eNOS-derived NO synthesis and vasodilation in mice. The Journal of Clinical Investigation. 121: 3747-55. PMID 21804187 DOI: 10.1172/Jci44778 |
0.461 |
|
2011 |
Karuppiah K, Druhan LJ, Chen CA, Smith T, Zweier JL, Sessa WC, Cardounel AJ. Suppression of eNOS-derived superoxide by caveolin-1: a biopterin-dependent mechanism. American Journal of Physiology. Heart and Circulatory Physiology. 301: H903-11. PMID 21724868 DOI: 10.1152/Ajpheart.00936.2010 |
0.476 |
|
2011 |
Sutendra G, Dromparis P, Wright P, Bonnet S, Haromy A, Hao Z, McMurtry MS, Michalak M, Vance JE, Sessa WC, Michelakis ED. The role of Nogo and the mitochondria-endoplasmic reticulum unit in pulmonary hypertension. Science Translational Medicine. 3: 88ra55. PMID 21697531 DOI: 10.1126/Scitranslmed.3002194 |
0.773 |
|
2011 |
Harrison KD, Park EJ, Gao N, Kuo A, Rush JS, Waechter CJ, Lehrman MA, Sessa WC. Nogo-B receptor is necessary for cellular dolichol biosynthesis and protein N-glycosylation. The Embo Journal. 30: 2490-500. PMID 21572394 DOI: 10.1038/Emboj.2011.147 |
0.751 |
|
2011 |
Albinsson S, Skoura A, Yu J, DiLorenzo A, Fernández-Hernando C, Offermanns S, Miano JM, Sessa WC. Smooth muscle miRNAs are critical for post-natal regulation of blood pressure and vascular function. Plos One. 6: e18869. PMID 21526127 DOI: 10.1371/Journal.Pone.0018869 |
0.353 |
|
2011 |
Zhang D, Utsumi T, Huang HC, Gao L, Sangwung P, Chung C, Shibao K, Okamoto K, Yamaguchi K, Groszmann RJ, Jozsef L, Hao Z, Sessa WC, Iwakiri Y. Reticulon 4B (Nogo-B) is a novel regulator of hepatic fibrosis. Hepatology (Baltimore, Md.). 53: 1306-15. PMID 21480333 DOI: 10.1002/Hep.24200 |
0.338 |
|
2011 |
Muto A, Yi T, Harrison KD, Dávalos A, Fancher TT, Ziegler KR, Feigel A, Kondo Y, Nishibe T, Sessa WC, Dardik A. Eph-B4 prevents venous adaptive remodeling in the adult arterial environment. The Journal of Experimental Medicine. 208: 561-75. PMID 21339325 DOI: 10.1084/Jem.20101854 |
0.765 |
|
2011 |
Briand N, Le Lay S, Sessa WC, Ferré P, Dugail I. Distinct roles of endothelial and adipocyte caveolin-1 in macrophage infiltration and adipose tissue metabolic activity. Diabetes. 60: 448-53. PMID 21270257 DOI: 10.2337/Db10-0856 |
0.362 |
|
2011 |
Di Lorenzo A, Manes TD, Davalos A, Wright PL, Sessa WC. Endothelial reticulon-4B (Nogo-B) regulates ICAM-1-mediated leukocyte transmigration and acute inflammation. Blood. 117: 2284-95. PMID 21183689 DOI: 10.1182/Blood-2010-04-281956 |
0.804 |
|
2011 |
Albinsson S, Sessa WC. Can microRNAs control vascular smooth muscle phenotypic modulation and the response to injury? Physiological Genomics. 43: 529-33. PMID 20841497 DOI: 10.1152/Physiolgenomics.00146.2010 |
0.301 |
|
2010 |
Wright PL, Yu J, Di YP, Homer RJ, Chupp G, Elias JA, Cohn L, Sessa WC. Epithelial reticulon 4B (Nogo-B) is an endogenous regulator of Th2-driven lung inflammation. The Journal of Experimental Medicine. 207: 2595-607. PMID 20975041 DOI: 10.1084/Jem.20100786 |
0.752 |
|
2010 |
Marin EP, Moeckel G, Al-Lamki R, Bradley J, Yan Q, Wang T, Wright PL, Yu J, Sessa WC. Identification and regulation of reticulon 4B (Nogo-B) in renal tubular epithelial cells. The American Journal of Pathology. 177: 2765-73. PMID 20971739 DOI: 10.2353/Ajpath.2010.100199 |
0.76 |
|
2010 |
Terasaka N, Westerterp M, Koetsveld J, Fernández-Hernando C, Yvan-Charvet L, Wang N, Sessa WC, Tall AR. ATP-binding cassette transporter G1 and high-density lipoprotein promote endothelial NO synthesis through a decrease in the interaction of caveolin-1 and endothelial NO synthase. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 2219-25. PMID 20798376 DOI: 10.1161/Atvbaha.110.213215 |
0.338 |
|
2010 |
Lazorchak AS, Liu D, Facchinetti V, Di Lorenzo A, Sessa WC, Schatz DG, Su B. Sin1-mTORC2 suppresses rag and il7r gene expression through Akt2 in B cells. Molecular Cell. 39: 433-43. PMID 20705244 DOI: 10.1016/J.Molcel.2010.07.031 |
0.384 |
|
2010 |
Sessa WC. A new way to lower blood pressure: pass the chili peppers please! Cell Metabolism. 12: 109-10. PMID 20674855 DOI: 10.1016/J.Cmet.2010.07.005 |
0.315 |
|
2010 |
Zheng X, Xu C, Di Lorenzo A, Kleaveland B, Zou Z, Seiler C, Chen M, Cheng L, Xiao J, He J, Pack MA, Sessa WC, Kahn ML. CCM3 signaling through sterile 20-like kinases plays an essential role during zebrafish cardiovascular development and cerebral cavernous malformations. The Journal of Clinical Investigation. 120: 2795-804. PMID 20592472 DOI: 10.1172/Jci39679 |
0.456 |
|
2010 |
Krieger MH, Di Lorenzo A, Teutsch C, Kauser K, Sessa WC. Telmisartan regresses left ventricular hypertrophy in caveolin-1-deficient mice. Laboratory Investigation; a Journal of Technical Methods and Pathology. 90: 1573-81. PMID 20585312 DOI: 10.1038/Labinvest.2010.116 |
0.302 |
|
2010 |
Dávalos A, Fernández-Hernando C, Sowa G, Derakhshan B, Lin MI, Lee JY, Zhao H, Luo R, Colangelo C, Sessa WC. Quantitative proteomics of caveolin-1-regulated proteins: characterization of polymerase i and transcript release factor/CAVIN-1 IN endothelial cells. Molecular & Cellular Proteomics : McP. 9: 2109-24. PMID 20585024 DOI: 10.1074/Mcp.M110.001289 |
0.644 |
|
2010 |
Fernández-Hernando C, Yu J, Dávalos A, Prendergast J, Sessa WC. Endothelial-specific overexpression of caveolin-1 accelerates atherosclerosis in apolipoprotein E-deficient mice. The American Journal of Pathology. 177: 998-1003. PMID 20581061 DOI: 10.2353/Ajpath.2010.091287 |
0.492 |
|
2010 |
Albinsson S, Suarez Y, Skoura A, Offermanns S, Miano JM, Sessa WC. MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 1118-26. PMID 20378849 DOI: 10.1161/Atvbaha.109.200873 |
0.312 |
|
2010 |
Sanchez-Madrid F, Sessa WC. Spotlight on mechanisms of vascular inflammation. Cardiovascular Research. 86: 171-3. PMID 20228399 DOI: 10.1093/Cvr/Cvq083 |
0.351 |
|
2010 |
Chidlow JH, Sessa WC. Caveolae, caveolins, and cavins: complex control of cellular signalling and inflammation. Cardiovascular Research. 86: 219-25. PMID 20202978 DOI: 10.1093/Cvr/Cvq075 |
0.372 |
|
2010 |
Muto A, Yi T, Harrison K, Davalos A, Sessa WC, Dardik A. SS6. Venous Specific Eph-B4 Regulates Vein Graft Thickening via Caveolin-1 Journal of Vascular Surgery. 51: 6S-7S. DOI: 10.1016/J.Jvs.2010.02.046 |
0.756 |
|
2009 |
Yu J, Fernández-Hernando C, Suarez Y, Schleicher M, Hao Z, Wright PL, DiLorenzo A, Kyriakides TR, Sessa WC. Reticulon 4B (Nogo-B) is necessary for macrophage infiltration and tissue repair. Proceedings of the National Academy of Sciences of the United States of America. 106: 17511-6. PMID 19805174 DOI: 10.1073/Pnas.0907359106 |
0.767 |
|
2009 |
Fernández-Hernando C, József L, Jenkins D, Di Lorenzo A, Sessa WC. Absence of Akt1 reduces vascular smooth muscle cell migration and survival and induces features of plaque vulnerability and cardiac dysfunction during atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 2033-40. PMID 19762778 DOI: 10.1161/Atvbaha.109.196394 |
0.406 |
|
2009 |
Harrison KD, Miao RQ, Fernandez-Hernándo C, Suárez Y, Dávalos A, Sessa WC. Nogo-B receptor stabilizes Niemann-Pick type C2 protein and regulates intracellular cholesterol trafficking. Cell Metabolism. 10: 208-18. PMID 19723497 DOI: 10.1016/J.Cmet.2009.07.003 |
0.759 |
|
2009 |
Schleicher M, Yu J, Murata T, Derakhshan B, Atochin D, Qian L, Kashiwagi S, Di Lorenzo A, Harrison KD, Huang PL, Sessa WC. The Akt1-eNOS axis illustrates the specificity of kinase-substrate relationships in vivo Science Signaling. 2: ra41. PMID 19654415 DOI: 10.1126/Scisignal.2000343 |
0.792 |
|
2009 |
Sessa WC. Molecular control of blood flow and angiogenesis: role of nitric oxide. Journal of Thrombosis and Haemostasis : Jth. 35-7. PMID 19630764 DOI: 10.1111/J.1538-7836.2009.03424.X |
0.436 |
|
2009 |
Di Lorenzo A, Fernández-Hernando C, Cirino G, Sessa WC. Akt1 is critical for acute inflammation and histamine-mediated vascular leakage. Proceedings of the National Academy of Sciences of the United States of America. 106: 14552-7. PMID 19622728 DOI: 10.1073/Pnas.0904073106 |
0.467 |
|
2009 |
Fernández-Hernando C, Yu J, Suárez Y, Rahner C, Dávalos A, Lasunción MA, Sessa WC. Genetic evidence supporting a critical role of endothelial caveolin-1 during the progression of atherosclerosis. Cell Metabolism. 10: 48-54. PMID 19583953 DOI: 10.1016/J.Cmet.2009.06.003 |
0.47 |
|
2009 |
Bernatchez PN, Sharma A, Kodaman P, Sessa WC. Myoferlin is critical for endocytosis in endothelial cells. American Journal of Physiology. Cell Physiology. 297: C484-92. PMID 19494235 DOI: 10.1152/Ajpcell.00498.2008 |
0.394 |
|
2009 |
Suárez Y, Sessa WC. MicroRNAs as novel regulators of angiogenesis. Circulation Research. 104: 442-54. PMID 19246688 DOI: 10.1161/Circresaha.108.191270 |
0.382 |
|
2009 |
Chidlow JH, Greer JJ, Anthoni C, Bernatchez P, Fernandez-Hernando C, Fernadez-Hernando C, Bruce M, Abdelbaqi M, Shukla D, Granger DN, Sessa WC, Kevil CG. Endothelial caveolin-1 regulates pathologic angiogenesis in a mouse model of colitis. Gastroenterology. 136: 575-84.e2. PMID 19111727 DOI: 10.1053/J.Gastro.2008.10.085 |
0.44 |
|
2008 |
Tang PC, Qin L, Zielonka J, Zhou J, Matte-Martone C, Bergaya S, van Rooijen N, Shlomchik WD, Min W, Sessa WC, Pober JS, Tellides G. MyD88-dependent, superoxide-initiated inflammation is necessary for flow-mediated inward remodeling of conduit arteries. The Journal of Experimental Medicine. 205: 3159-71. PMID 19064699 DOI: 10.1084/Jem.20081298 |
0.425 |
|
2008 |
Murata T, Lin MI, Aritake K, Matsumoto S, Narumiya S, Ozaki H, Urade Y, Hori M, Sessa WC. Role of prostaglandin D2 receptor DP as a suppressor of tumor hyperpermeability and angiogenesis in vivo. Proceedings of the National Academy of Sciences of the United States of America. 105: 20009-14. PMID 19060214 DOI: 10.1073/Pnas.0805171105 |
0.629 |
|
2008 |
Zhang H, He Y, Dai S, Xu Z, Luo Y, Wan T, Luo D, Jones D, Tang S, Chen H, Sessa WC, Min W. AIP1 functions as an endogenous inhibitor of VEGFR2-mediated signaling and inflammatory angiogenesis in mice. The Journal of Clinical Investigation. 118: 3904-16. PMID 19033661 DOI: 10.1172/Jci36168 |
0.474 |
|
2008 |
Kritz AB, Yu J, Wright PL, Wan S, George SJ, Halliday C, Kang N, Sessa WC, Baker AH. In vivo modulation of Nogo-B attenuates neointima formation. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1798-804. PMID 18781142 DOI: 10.1038/Mt.2008.188 |
0.775 |
|
2008 |
Suárez Y, Fernández-Hernando C, Yu J, Gerber SA, Harrison KD, Pober JS, Iruela-Arispe ML, Merkenschlager M, Sessa WC. Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis. Proceedings of the National Academy of Sciences of the United States of America. 105: 14082-7. PMID 18779589 DOI: 10.1073/Pnas.0804597105 |
0.77 |
|
2008 |
Derakhshan B, Harrison KD, Miao QR, Sessa WC. Chapter 1 Approaches for Studying Angiogenesis-Related Signal Transduction Methods in Enzymology. 443: 1-23. PMID 18772008 DOI: 10.1016/S0076-6879(08)02001-6 |
0.798 |
|
2008 |
Krady MM, Zeng J, Yu J, MacLauchlan S, Skokos EA, Tian W, Bornstein P, Sessa WC, Kyriakides TR. Thrombospondin-2 modulates extracellular matrix remodeling during physiological angiogenesis. The American Journal of Pathology. 173: 879-91. PMID 18688033 DOI: 10.2353/Ajpath.2008.080128 |
0.381 |
|
2008 |
Rodriguez-Feo JA, Hellings WE, Moll FL, De Vries JP, van Middelaar BJ, Algra A, Sluijter J, Velema E, van den Broek T, Sessa WC, De Kleijn DP, Pasterkamp G. Caveolin-1 influences vascular protease activity and is a potential stabilizing factor in human atherosclerotic disease. Plos One. 3: e2612. PMID 18596970 DOI: 10.1371/Journal.Pone.0002612 |
0.374 |
|
2008 |
Facchinetti V, Ouyang W, Wei H, Soto N, Lazorchak A, Gould C, Lowry C, Newton AC, Mao Y, Miao RQ, Sessa WC, Qin J, Zhang P, Su B, Jacinto E. The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C. The Embo Journal. 27: 1932-43. PMID 18566586 DOI: 10.1038/Emboj.2008.120 |
0.345 |
|
2008 |
Schleicher M, Sessa WC. Are the mechanisms for NO-dependent vascular remodeling different from vasorelaxation in vivo? Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1207-8. PMID 18565841 DOI: 10.1161/Atvbaha.108.167403 |
0.483 |
|
2008 |
Tourkina E, Richard M, Gööz P, Bonner M, Pannu J, Harley R, Bernatchez PN, Sessa WC, Silver RM, Hoffman S. Antifibrotic properties of caveolin-1 scaffolding domain in vitro and in vivo. American Journal of Physiology. Lung Cellular and Molecular Physiology. 294: L843-61. PMID 18203815 DOI: 10.1152/Ajplung.00295.2007 |
0.31 |
|
2008 |
Schleicher M, Shepherd BR, Suarez Y, Fernandez-Hernando C, Yu J, Pan Y, Acevedo LM, Shadel GS, Sessa WC. Prohibitin-1 maintains the angiogenic capacity of endothelial cells by regulating mitochondrial function and senescence. The Journal of Cell Biology. 180: 101-12. PMID 18195103 DOI: 10.1083/Jcb.200706072 |
0.785 |
|
2008 |
Sowa G, Xie L, Xu L, Sessa WC. Serine 23 and 36 phosphorylation of caveolin-2 is differentially regulated by targeting to lipid raft/caveolae and in mitotic endothelial cells. Biochemistry. 47: 101-11. PMID 18081315 DOI: 10.1021/Bi701709S |
0.428 |
|
2008 |
Miao RQ, Fontana J, Fulton D, Lin MI, Harrison KD, Sessa WC. Dominant-negative Hsp90 reduces VEGF-stimulated nitric oxide release and migration in endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 105-11. PMID 17975117 DOI: 10.1161/Atvbaha.107.155499 |
0.81 |
|
2008 |
Schleicher M, Yu J, Murata T, Harrisson KD, Huang PL, Sessa WC. O48. Phosphorylation of eNOS on Serine 1176 by Akt1 is indispensable for pathophysiological angiogenesis Nitric Oxide. 19: 31. DOI: 10.1016/J.Niox.2008.06.049 |
0.337 |
|
2007 |
Fernández-Hernando C, Ackah E, Yu J, Suárez Y, Murata T, Iwakiri Y, Prendergast J, Miao RQ, Birnbaum MJ, Sessa WC. Loss of Akt1 leads to severe atherosclerosis and occlusive coronary artery disease. Cell Metabolism. 6: 446-57. PMID 18054314 DOI: 10.1016/J.Cmet.2007.10.007 |
0.8 |
|
2007 |
Li L, Hisamoto K, Kim KH, Haynes MP, Bauer PM, Sanjay A, Collinge M, Baron R, Sessa WC, Bender JR. Variant estrogen receptor-c-Src molecular interdependence and c-Src structural requirements for endothelial NO synthase activation. Proceedings of the National Academy of Sciences of the United States of America. 104: 16468-73. PMID 17921256 DOI: 10.1073/Pnas.0704315104 |
0.366 |
|
2007 |
Pober JS, Sessa WC. Evolving functions of endothelial cells in inflammation. Nature Reviews. Immunology. 7: 803-15. PMID 17893694 DOI: 10.1038/Nri2171 |
0.42 |
|
2007 |
Murata T, Lin MI, Huang Y, Yu J, Bauer PM, Giordano FJ, Sessa WC. Reexpression of caveolin-1 in endothelium rescues the vascular, cardiac, and pulmonary defects in global caveolin-1 knockout mice. The Journal of Experimental Medicine. 204: 2373-82. PMID 17893196 DOI: 10.1084/Jem.20062340 |
0.626 |
|
2007 |
Bernatchez PN, Acevedo L, Fernandez-Hernando C, Murata T, Chalouni C, Kim J, Erdjument-Bromage H, Shah V, Gratton JP, McNally EM, Tempst P, Sessa WC. Myoferlin regulates vascular endothelial growth factor receptor-2 stability and function. The Journal of Biological Chemistry. 282: 30745-53. PMID 17702744 DOI: 10.1074/Jbc.M704798200 |
0.804 |
|
2007 |
Atochin DN, Wang A, Liu VW, Critchlow JD, Dantas AP, Looft-Wilson R, Murata T, Salomone S, Shin HK, Ayata C, Moskowitz MA, Michel T, Sessa WC, Huang PL. The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivo. The Journal of Clinical Investigation. 117: 1961-7. PMID 17557122 DOI: 10.1172/Jci29877 |
0.437 |
|
2007 |
Kudo FA, Muto A, Maloney SP, Pimiento JM, Bergaya S, Fitzgerald TN, Westvik TS, Frattini JC, Breuer CK, Cha CH, Nishibe T, Tellides G, Sessa WC, Dardik A. Venous identity is lost but arterial identity is not gained during vein graft adaptation. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 1562-71. PMID 17463332 DOI: 10.1161/Atvbaha.107.143032 |
0.305 |
|
2007 |
Murata T, Lin MI, Stan RV, Bauer PM, Yu J, Sessa WC. Genetic evidence supporting caveolae microdomain regulation of calcium entry in endothelial cells. The Journal of Biological Chemistry. 282: 16631-43. PMID 17416589 DOI: 10.1074/Jbc.M607948200 |
0.601 |
|
2007 |
Rodriguez-Feo JA, Hellings WE, Verhoeven BA, Moll FL, de Kleijn DP, Prendergast J, Gao Y, van der Graaf Y, Tellides G, Sessa WC, Pasterkamp G. Low levels of Nogo-B in human carotid atherosclerotic plaques are associated with an atheromatous phenotype, restenosis, and stenosis severity. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 1354-60. PMID 17413036 DOI: 10.1161/Atvbaha.107.140913 |
0.312 |
|
2007 |
Morales-Ruiz M, Fondevila C, Muñoz-Luque J, Tugues S, Rodríguez-Laiz G, Cejudo-Martín P, Romero JM, Navasa M, Fuster J, Arroyo V, Sessa WC, García-Valdecasas JC, Jiménez W. Gene transduction of an active mutant of akt exerts cytoprotection and reduces graft injury after liver transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 7: 769-78. PMID 17391122 DOI: 10.1111/J.1600-6143.2006.01720.X |
0.321 |
|
2007 |
Suárez Y, Fernández-Hernando C, Pober JS, Sessa WC. Dicer dependent microRNAs regulate gene expression and functions in human endothelial cells. Circulation Research. 100: 1164-73. PMID 17379831 DOI: 10.1161/01.Res.0000265065.26744.17 |
0.365 |
|
2007 |
Lin MI, Yu J, Murata T, Sessa WC. Caveolin-1-deficient mice have increased tumor microvascular permeability, angiogenesis, and growth. Cancer Research. 67: 2849-56. PMID 17363608 DOI: 10.1158/0008-5472.Can-06-4082 |
0.604 |
|
2007 |
Zhang H, Luo Y, Zhang W, He Y, Dai S, Zhang R, Huang Y, Bernatchez P, Giordano FJ, Shadel G, Sessa WC, Min W. Endothelial-specific expression of mitochondrial thioredoxin improves endothelial cell function and reduces atherosclerotic lesions. The American Journal of Pathology. 170: 1108-20. PMID 17322393 DOI: 10.2353/Ajpath.2007.060960 |
0.455 |
|
2007 |
Marin E, Sessa WC. Role of endothelial-derived nitric oxide in hypertension and renal disease. Current Opinion in Nephrology and Hypertension. 16: 105-10. PMID 17293684 DOI: 10.1097/Mnh.0B013E328017F893 |
0.382 |
|
2007 |
Sessa WC. Nitric oxide synthase inhibition and cancer. The Lancet. Oncology. 8: 88-9. PMID 17267319 DOI: 10.1016/S1470-2045(07)70006-2 |
0.318 |
|
2007 |
Pyriochou A, Zhou Z, Koika V, Petrou C, Cordopatis P, Sessa WC, Papapetropoulos A. The phosphodiesterase 5 inhibitor sildenafil stimulates angiogenesis through a protein kinase G/MAPK pathway. Journal of Cellular Physiology. 211: 197-204. PMID 17226792 DOI: 10.1002/Jcp.20929 |
0.439 |
|
2007 |
Paszkowiak JJ, Maloney SP, Kudo FA, Muto A, Teso D, Rutland RC, Westvik TS, Pimiento JM, Tellides G, Sessa WC, Dardik A. Evidence supporting changes in Nogo-B levels as a marker of neointimal expansion but not adaptive arterial remodeling. Vascular Pharmacology. 46: 293-301. PMID 17207665 DOI: 10.1016/J.Vph.2006.11.003 |
0.341 |
|
2007 |
Hooper WC, Catravas JD, Heistad DD, Sessa WC, Mensah GA. Vascular endothelium summary statement I: Health promotion and chronic disease prevention. Vascular Pharmacology. 46: 315-7. PMID 17197248 DOI: 10.1016/J.Vph.2006.10.014 |
0.33 |
|
2006 |
Iwakiri Y, Satoh A, Chatterjee S, Toomre DK, Chalouni CM, Fulton D, Groszmann RJ, Shah VH, Sessa WC. Nitric oxide synthase generates nitric oxide locally to regulate compartmentalized protein S-nitrosylation and protein trafficking. Proceedings of the National Academy of Sciences of the United States of America. 103: 19777-82. PMID 17170139 DOI: 10.1073/Pnas.0605907103 |
0.362 |
|
2006 |
Luo D, Luo Y, He Y, Zhang H, Zhang R, Li X, Dobrucki WL, Sinusas AJ, Sessa WC, Min W. Differential functions of tumor necrosis factor receptor 1 and 2 signaling in ischemia-mediated arteriogenesis and angiogenesis. The American Journal of Pathology. 169: 1886-98. PMID 17071609 DOI: 10.2353/Ajpath.2006.060603 |
0.488 |
|
2006 |
Lin MI, Sessa WC. Vascular endothelial growth factor signaling to endothelial nitric oxide synthase: more than a FLeeTing moment. Circulation Research. 99: 666-8. PMID 17008595 DOI: 10.1161/01.Res.0000245430.24075.A4 |
0.666 |
|
2006 |
He Y, Luo Y, Tang S, Rajantie I, Salven P, Heil M, Zhang R, Luo D, Li X, Chi H, Yu J, Carmeliet P, Schaper W, Sinusas AJ, Sessa WC, et al. Critical function of Bmx/Etk in ischemia-mediated arteriogenesis and angiogenesis Journal of Clinical Investigation. 116: 2344-2355. PMID 16932810 DOI: 10.1172/Jci28123 |
0.431 |
|
2006 |
Phung TL, Ziv K, Dabydeen D, Eyiah-Mensah G, Riveros M, Perruzzi C, Sun J, Monahan-Earley RA, Shiojima I, Nagy JA, Lin MI, Walsh K, Dvorak AM, Briscoe DM, Neeman M, ... Sessa WC, et al. Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin Cancer Cell. 10: 159-170. PMID 16904613 DOI: 10.1016/J.Ccr.2006.07.003 |
0.643 |
|
2006 |
Fernández-Hernando C, Fukata M, Bernatchez PN, Fukata Y, Lin MI, Bredt DS, Sessa WC. Identification of Golgi-localized acyl transferases that palmitoylate and regulate endothelial nitric oxide synthase. The Journal of Cell Biology. 174: 369-77. PMID 16864653 DOI: 10.1083/Jcb.200601051 |
0.659 |
|
2006 |
Miao RQ, Gao Y, Harrison KD, Prendergast J, Acevedo LM, Yu J, Hu F, Strittmatter SM, Sessa WC. Identification of a receptor necessary for Nogo-B stimulated chemotaxis and morphogenesis of endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 10997-1002. PMID 16835300 DOI: 10.1073/Pnas.0602427103 |
0.8 |
|
2006 |
Bhandari V, Choo-Wing R, Chapoval SP, Lee CG, Tang C, Kim YK, Ma B, Baluk P, Lin MI, McDonald DM, Homer RJ, Sessa WC, Elias JA. Essential role of nitric oxide in VEGF-induced, asthma-like angiogenic, inflammatory, mucus, and physiologic responses in the lung. Proceedings of the National Academy of Sciences of the United States of America. 103: 11021-6. PMID 16832062 DOI: 10.1073/Pnas.0601057103 |
0.665 |
|
2006 |
Boo YC, Kim HJ, Song H, Fulton D, Sessa W, Jo H. Coordinated regulation of endothelial nitric oxide synthase activity by phosphorylation and subcellular localization. Free Radical Biology & Medicine. 41: 144-53. PMID 16781462 DOI: 10.1016/J.Freeradbiomed.2006.03.024 |
0.413 |
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2006 |
Hatakeyama T, Pappas PJ, Hobson RW, Boric MP, Sessa WC, Durán WN. Endothelial nitric oxide synthase regulates microvascular hyperpermeability in vivo. The Journal of Physiology. 574: 275-81. PMID 16675496 DOI: 10.1113/Jphysiol.2006.108175 |
0.441 |
|
2006 |
Yu J, Bergaya S, Murata T, Alp IF, Bauer MP, Lin MI, Drab M, Kurzchalia TV, Stan RV, Sessa WC. Direct evidence for the role of caveolin-1 and caveolae in mechanotransduction and remodeling of blood vessels. The Journal of Clinical Investigation. 116: 1284-91. PMID 16670769 DOI: 10.1172/Jci27100 |
0.613 |
|
2006 |
Qian HS, Liu P, Huw LY, Orme A, Halks-Miller M, Hill SM, Jin F, Kretschmer P, Blasko E, Cashion L, Szymanski P, Vergona R, Harkins R, Yu J, Sessa WC, et al. Effective treatment of vascular endothelial growth factor refractory hindlimb ischemia by a mutant endothelial nitric oxide synthase gene. Gene Therapy. 13: 1342-50. PMID 16642030 DOI: 10.1038/sj.gt.3302781 |
0.332 |
|
2006 |
Abraldes JG, Iwakiri Y, Loureiro-Silva M, Haq O, Sessa WC, Groszmann RJ. Mild increases in portal pressure upregulate vascular endothelial growth factor and endothelial nitric oxide synthase in the intestinal microcirculatory bed, leading to a hyperdynamic state. American Journal of Physiology. Gastrointestinal and Liver Physiology. 290: G980-7. PMID 16603731 DOI: 10.1152/Ajpgi.00336.2005 |
0.438 |
|
2006 |
Zhang Q, Church JE, Jagnandan D, Catravas JD, Sessa WC, Fulton D. Functional relevance of Golgi- and plasma membrane-localized endothelial NO synthase in reconstituted endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 1015-21. PMID 16514082 DOI: 10.1161/01.Atv.0000216044.49494.C4 |
0.418 |
|
2006 |
Yu J, Lei L, Liang Y, Hinh L, Hickey RP, Huang Y, Liu D, Yeh JL, Rebar E, Case C, Spratt K, Sessa WC, Giordano FJ. An engineered VEGF-activating zinc finger protein transcription factor improves blood flow and limb salvage in advanced-age mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 479-81. PMID 16423874 DOI: 10.1096/Fj.04-3670Fje |
0.427 |
|
2006 |
Iwakiri Y, Satoh A, Chatterjee S, Shah V, Toomre D, Chalouni CM, Fulton D, Groszmann R, Sessa WC. P013. Nitric oxide synthase establishes a local nitric oxide gradient regulating S-nitrosylation and protein secretion Nitric Oxide. 14: 21. DOI: 10.1016/J.Niox.2006.04.072 |
0.352 |
|
2006 |
Fernández C, Fukata M, Bernatchez P, Fukata Y, Lin M, Bredt DS, Sessa WC. O08. Identification of Golgi localized acyl transferases that palmitoylate and regulate endothelial nitric oxide synthase Nitric Oxide. 14: 3. DOI: 10.1016/J.Niox.2006.04.012 |
0.614 |
|
2006 |
Maloney SP, Yakimov A, Muto A, Tang P, Pimiento J, Kudo F, Westvik T, Dudrick S, Sessa W, Tellides G, Dardik A. Murine carotid aneurysms develop without down regulation of Nogo-B expression: A novel model for human thoracic aneurysms Journal of the American College of Surgeons. 203: S22. DOI: 10.1016/J.Jamcollsurg.2006.05.053 |
0.306 |
|
2005 |
Partovian C, Zhuang Z, Moodie K, Lin M, Ouchi N, Sessa WC, Walsh K, Simons M. PKCalpha activates eNOS and increases arterial blood flow in vivo. Circulation Research. 97: 482-7. PMID 16081872 DOI: 10.1161/01.Res.0000179775.04114.45 |
0.671 |
|
2005 |
Ackah E, Yu J, Zoellner S, Iwakiri Y, Skurk C, Shibata R, Ouchi N, Easton RM, Galasso G, Birnbaum MJ, Walsh K, Sessa WC. Akt1/protein kinase Balpha is critical for ischemic and VEGF-mediated angiogenesis. The Journal of Clinical Investigation. 115: 2119-27. PMID 16075056 DOI: 10.1172/Jci24726 |
0.824 |
|
2005 |
Yu J, deMuinck ED, Zhuang Z, Drinane M, Kauser K, Rubanyi GM, Qian HS, Murata T, Escalante B, Sessa WC. Endothelial nitric oxide synthase is critical for ischemic remodeling, mural cell recruitment, and blood flow reserve. Proceedings of the National Academy of Sciences of the United States of America. 102: 10999-1004. PMID 16043715 DOI: 10.1073/Pnas.0501444102 |
0.459 |
|
2005 |
Papapetropoulos A, Zhou Z, Gerassimou C, Yetik G, Venema RC, Roussos C, Sessa WC, Catravas JD. Interaction between the 90-kDa heat shock protein and soluble guanylyl cyclase: physiological significance and mapping of the domains mediating binding. Molecular Pharmacology. 68: 1133-41. PMID 16024662 DOI: 10.1124/Mol.105.012682 |
0.302 |
|
2005 |
Sessa WC. Regulation of endothelial derived nitric oxide in health and disease. MemóRias Do Instituto Oswaldo Cruz. 100: 15-8. PMID 15962093 DOI: 10.1590/S0074-02762005000900004 |
0.437 |
|
2005 |
Jagnandan D, Sessa WC, Fulton D. Intracellular location regulates calcium-calmodulin-dependent activation of organelle-restricted eNOS. American Journal of Physiology. Cell Physiology. 289: C1024-33. PMID 15917301 DOI: 10.1152/Ajpcell.00162.2005 |
0.399 |
|
2005 |
Zhang R, Luo D, Miao R, Bai L, Ge Q, Sessa WC, Min W. Hsp90-Akt phosphorylates ASK1 and inhibits ASK1-mediated apoptosis. Oncogene. 24: 3954-63. PMID 15782121 DOI: 10.1038/Sj.Onc.1208548 |
0.368 |
|
2005 |
Bucci M, Roviezzo F, Posadas I, Yu J, Parente L, Sessa WC, Ignarro LJ, Cirino G. Endothelial nitric oxide synthase activation is critical for vascular leakage during acute inflammation in vivo Proceedings of the National Academy of Sciences of the United States of America. 102: 904-908. PMID 15640348 DOI: 10.1073/Pnas.0408906102 |
0.497 |
|
2005 |
Bernatchez PN, Bauer PM, Yu J, Prendergast JS, He P, Sessa WC. Dissecting the molecular control of endothelial NO synthase by caveolin-1 using cell-permeable peptides. Proceedings of the National Academy of Sciences of the United States of America. 102: 761-6. PMID 15637154 DOI: 10.1073/Pnas.0407224102 |
0.385 |
|
2005 |
Bauer PM, Yu J, Chen Y, Hickey R, Bernatchez PN, Looft-Wilson R, Huang Y, Giordano F, Stan RV, Sessa WC. Endothelial-specific expression of caveolin-1 impairs microvascular permeability and angiogenesis. Proceedings of the National Academy of Sciences of the United States of America. 102: 204-9. PMID 15615855 DOI: 10.1073/Pnas.0406092102 |
0.539 |
|
2005 |
Sorenson J, Santhanam AV, Smith LA, Akiyama M, Sessa WC, Katusic ZS. Expression and function of recombinant S1179D endothelial NO synthase in human pial arteries. Stroke; a Journal of Cerebral Circulation. 36: 158-60. PMID 15569867 DOI: 10.1161/01.Str.0000150489.47080.67 |
0.397 |
|
2004 |
Lin MI, Sessa WC. Antiangiogenic therapy: creating a unique "window" of opportunity. Cancer Cell. 6: 529-31. PMID 15607955 DOI: 10.1016/J.Ccr.2004.12.003 |
0.523 |
|
2004 |
Koh KP, Wang Y, Yi T, Shiao SL, Lorber MI, Sessa WC, Tellides G, Pober JS. T cell-mediated vascular dysfunction of human allografts results from IFN-gamma dysregulation of NO synthase. The Journal of Clinical Investigation. 114: 846-56. PMID 15372109 DOI: 10.1172/Jci21767 |
0.396 |
|
2004 |
Gratton JP, Bernatchez P, Sessa WC. Caveolae and caveolins in the cardiovascular system. Circulation Research. 94: 1408-17. PMID 15192036 DOI: 10.1161/01.Res.0000129178.56294.17 |
0.394 |
|
2004 |
Hagendoorn J, Padera TP, Kashiwagi S, Isaka N, Noda F, Lin MI, Huang PL, Sessa WC, Fukumura D, Jain RK. Endothelial nitric oxide synthase regulates microlymphatic flow via collecting lymphatics. Circulation Research. 95: 204-9. PMID 15192027 DOI: 10.1161/01.Res.0000135549.72828.24 |
0.628 |
|
2004 |
Sessa WC. eNOS at a glance. Journal of Cell Science. 117: 2427-9. PMID 15159447 DOI: 10.1242/Jcs.01165 |
0.44 |
|
2004 |
Fulton D, Babbitt R, Zoellner S, Fontana J, Acevedo L, McCabe TJ, Iwakiri Y, Sessa WC. Targeting of endothelial nitric-oxide synthase to the cytoplasmic face of the Golgi complex or plasma membrane regulates Akt- versus calcium-dependent mechanisms for nitric oxide release. The Journal of Biological Chemistry. 279: 30349-57. PMID 15136572 DOI: 10.1074/Jbc.M402155200 |
0.785 |
|
2004 |
Kuhlencordt PJ, Rosel E, Gerszten RE, Morales-Ruiz M, Dombkowski D, Atkinson WJ, Han F, Preffer F, Rosenzweig A, Sessa WC, Gimbrone MA, Ertl G, Huang PL. Role of endothelial nitric oxide synthase in endothelial activation: insights from eNOS knockout endothelial cells. American Journal of Physiology. Cell Physiology. 286: C1195-202. PMID 15075219 DOI: 10.1152/Ajpcell.00546.2002 |
0.467 |
|
2004 |
Acevedo L, Yu J, Erdjument-Bromage H, Miao RQ, Kim JE, Fulton D, Tempst P, Strittmatter SM, Sessa WC. A new role for Nogo as a regulator of vascular remodeling. Nature Medicine. 10: 382-8. PMID 15034570 DOI: 10.1038/Nm1020 |
0.804 |
|
2004 |
Bucci M, Roviezzo F, Brancaleone V, Lin MI, Di Lorenzo A, Cicala C, Pinto A, Sessa WC, Farneti S, Fiorucci S, Cirino G. Diabetic mouse angiopathy is linked to progressive sympathetic receptor deletion coupled to an enhanced caveolin-1 expression. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 721-6. PMID 14962949 DOI: 10.1161/01.Atv.0000122362.44628.09 |
0.565 |
|
2004 |
Payne GW, Madri JA, Sessa WC, Segal SS. Histamine inhibits conducted vasodilation through endothelium-derived NO production in arterioles of mouse skeletal muscle. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 280-6. PMID 14769822 DOI: 10.1096/Fj.03-0752Com |
0.359 |
|
2004 |
Papapetropoulos A, Fulton D, Lin MI, Fontana J, McCabe TJ, Zoellner S, García-Cardeña G, Zhou Z, Gratton JP, Sessa WC. Vanadate is a potent activator of endothelial nitric-oxide synthase: evidence for the role of the serine/threonine kinase Akt and the 90-kDa heat shock protein. Molecular Pharmacology. 65: 407-15. PMID 14742683 DOI: 10.1124/Mol.65.2.407 |
0.813 |
|
2004 |
Wang Y, Burns WR, Tang PC, Yi T, Schechner JS, Zerwes HG, Sessa WC, Lorber MI, Pober JS, Tellides G. Interferon-gamma plays a nonredundant role in mediating T cell-dependent outward vascular remodeling of allogeneic human coronary arteries. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 606-8. PMID 14734640 DOI: 10.1096/Fj.03-0840Fje |
0.337 |
|
2004 |
Sessa WC. Atheroprotection in the abence of "caves": is it the fat, the vessels, or both? Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 4-6. PMID 14707034 DOI: 10.1161/01.Atv.0000102552.84528.8F |
0.364 |
|
2004 |
Ou J, Fontana JT, Ou Z, Jones DW, Ackerman AW, Oldham KT, Yu J, Sessa WC, Pritchard KA. Heat shock protein 90 and tyrosine kinase regulate eNOS NO* generation but not NO* bioactivity. American Journal of Physiology. Heart and Circulatory Physiology. 286: H561-9. PMID 14551044 DOI: 10.1152/Ajpheart.00736.2003 |
0.779 |
|
2004 |
Yu J, Hickey R, Huang Y, Rebar E, Sessa WC, Giordano FJ. 1049. Engineered ZFPs Can Prevent Limb Loss in Mice Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.994 |
0.379 |
|
2004 |
Frattini JC, Sessa W, Sumpio B, Dardik A. Effects of turbulent flow on cell adhesion molecule expression in endothelial cells Journal of the American College of Surgeons. 199: 112. DOI: 10.1016/J.Jamcollsurg.2004.05.253 |
0.312 |
|
2004 |
Koh KP, Wang Y, Yi T, Lorber MI, Sessa WC, Tellides G, Pober JS. HUMAN ALLOGENEIC T CELL-MEDIATED VASCULAR DYSFUNCTION DEPENDS ON INTERFERON-GAMMA Cardiovascular Pathology. 13: 9. DOI: 10.1016/J.Carpath.2004.03.021 |
0.362 |
|
2003 |
Fortugno P, Beltrami E, Plescia J, Fontana J, Pradhan D, Marchisio PC, Sessa WC, Altieri DC. Regulation of survivin function by Hsp90. Proceedings of the National Academy of Sciences of the United States of America. 100: 13791-6. PMID 14614132 DOI: 10.1073/Pnas.2434345100 |
0.715 |
|
2003 |
Minshall RD, Sessa WC, Stan RV, Anderson RG, Malik AB. Caveolin regulation of endothelial function. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L1179-83. PMID 14604847 DOI: 10.1152/Ajplung.00242.2003 |
0.442 |
|
2003 |
Tsai MH, Iwakiri Y, Cadelina G, Sessa WC, Groszmann RJ. Mesenteric vasoconstriction triggers nitric oxide overproduction in the superior mesenteric artery of portal hypertensive rats. Gastroenterology. 125: 1452-61. PMID 14598261 DOI: 10.1016/J.Gastro.2003.07.014 |
0.329 |
|
2003 |
Boo YC, Sorescu GP, Bauer PM, Fulton D, Kemp BE, Harrison DG, Sessa WC, Jo H. Endothelial NO synthase phosphorylated at SER635 produces NO without requiring intracellular calcium increase. Free Radical Biology & Medicine. 35: 729-41. PMID 14583337 DOI: 10.1016/S0891-5849(03)00397-6 |
0.386 |
|
2003 |
Jiang J, Cyr D, Babbitt RW, Sessa WC, Patterson C. Chaperone-dependent regulation of endothelial nitric-oxide synthase intracellular trafficking by the co-chaperone/ubiquitin ligase CHIP. The Journal of Biological Chemistry. 278: 49332-41. PMID 14507928 DOI: 10.1074/Jbc.M304738200 |
0.464 |
|
2003 |
Lin MI, Fulton D, Babbitt R, Fleming I, Busse R, Pritchard KA, Sessa WC. Phosphorylation of threonine 497 in endothelial nitric-oxide synthase coordinates the coupling of L-arginine metabolism to efficient nitric oxide production. The Journal of Biological Chemistry. 278: 44719-26. PMID 12952971 DOI: 10.1074/Jbc.M302836200 |
0.659 |
|
2003 |
Gratton JP, Lin MI, Yu J, Weiss ED, Jiang ZL, Fairchild TA, Iwakiri Y, Groszmann R, Claffey KP, Cheng YC, Sessa WC. Selective inhibition of tumor microvascular permeability by cavtratin blocks tumor progression in mice. Cancer Cell. 4: 31-9. PMID 12892711 DOI: 10.1016/S1535-6108(03)00168-5 |
0.565 |
|
2003 |
Morales-Ruiz M, Cejudo-Martín P, Fernández-Varo G, Tugues S, Ros J, Angeli P, Rivera F, Arroyo V, Rodés J, Sessa WC, Jiménez W. Transduction of the liver with activated Akt normalizes portal pressure in cirrhotic rats. Gastroenterology. 125: 522-31. PMID 12891555 DOI: 10.1016/S0016-5085(03)00909-0 |
0.348 |
|
2003 |
Post H, Kajstura J, Lei B, Sessa WC, Byrne B, Anversa P, Hintze TH, Recchia FA. Adeno-associated virus mediated gene delivery into coronary microvessels of chronically instrumented dogs. Journal of Applied Physiology (Bethesda, Md. : 1985). 95: 1688-94. PMID 12844500 DOI: 10.1152/Japplphysiol.00896.2002 |
0.301 |
|
2003 |
Hendrickson H, Chatterjee S, Cao S, Morales Ruiz M, Sessa WC, Shah V. Influence of caveolin on constitutively activated recombinant eNOS: insights into eNOS dysfunction in BDL rat liver. American Journal of Physiology. Gastrointestinal and Liver Physiology. 285: G652-60. PMID 12829439 DOI: 10.1152/Ajpgi.00143.2003 |
0.335 |
|
2003 |
Peterson TE, Guicciardi ME, Gulati R, Kleppe LS, Mueske CS, Mookadam M, Sowa G, Gores GJ, Sessa WC, Simari RD. Caveolin-1 can regulate vascular smooth muscle cell fate by switching platelet-derived growth factor signaling from a proliferative to an apoptotic pathway. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 1521-7. PMID 12816877 DOI: 10.1161/01.Atv.0000081743.35125.05 |
0.378 |
|
2003 |
Sowa G, Pypaert M, Fulton D, Sessa WC. The phosphorylation of caveolin-2 on serines 23 and 36 modulates caveolin-1-dependent caveolae formation. Proceedings of the National Academy of Sciences of the United States of America. 100: 6511-6. PMID 12743374 DOI: 10.1073/Pnas.1031672100 |
0.358 |
|
2003 |
Payne GW, Madri JA, Sessa WC, Segal SS. Abolition of arteriolar dilation but not constriction to histamine in cremaster muscle of eNOS-/- mice. American Journal of Physiology. Heart and Circulatory Physiology. 285: H493-8. PMID 12689855 DOI: 10.1152/Ajpheart.00071.2003 |
0.374 |
|
2003 |
Bauer PM, Fulton D, Boo YC, Sorescu GP, Kemp BE, Jo H, Sessa WC. Compensatory phosphorylation and protein-protein interactions revealed by loss of function and gain of function mutants of multiple serine phosphorylation sites in endothelial nitric-oxide synthase. The Journal of Biological Chemistry. 278: 14841-9. PMID 12591925 DOI: 10.1074/Jbc.M211926200 |
0.371 |
|
2003 |
Cirino G, Fiorucci S, Sessa WC. Endothelial nitric oxide synthase: the Cinderella of inflammation? Trends in Pharmacological Sciences. 24: 91-5. PMID 12559774 DOI: 10.1016/S0165-6147(02)00049-4 |
0.489 |
|
2003 |
Haynes MP, Li L, Sinha D, Russell KS, Hisamoto K, Baron R, Collinge M, Sessa WC, Bender JR. Src kinase mediates phosphatidylinositol 3-kinase/Akt-dependent rapid endothelial nitric-oxide synthase activation by estrogen Journal of Biological Chemistry. 278: 2118-2123. PMID 12431978 DOI: 10.1074/Jbc.M210828200 |
0.384 |
|
2002 |
Nedvetsky PI, Sessa WC, Schmidt HH. There's NO binding like NOS binding: protein-protein interactions in NO/cGMP signaling. Proceedings of the National Academy of Sciences of the United States of America. 99: 16510-2. PMID 12486234 DOI: 10.1073/Pnas.262701999 |
0.367 |
|
2002 |
Iwakiri Y, Cadelina G, Sessa WC, Groszmann RJ. Mice with targeted deletion of eNOS develop hyperdynamic circulation associated with portal hypertension. American Journal of Physiology. Gastrointestinal and Liver Physiology. 283: G1074-81. PMID 12381520 DOI: 10.1152/Ajpgi.00145.2002 |
0.388 |
|
2002 |
Napoli C, Ackah E, De Nigris F, Del Soldato P, D'Armiento FP, Crimi E, Condorelli M, Sessa WC. Chronic treatment with nitric oxide-releasing aspirin reduces plasma low-density lipoprotein oxidation and oxidative stress, arterial oxidation-specific epitopes, and atherogenesis in hypercholesterolemic mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 12467-70. PMID 12209007 DOI: 10.1073/Pnas.192244499 |
0.783 |
|
2002 |
Blanc-Brude OP, Yu J, Simosa H, Conte MS, Sessa WC, Altieri DC. Inhibitor of apoptosis protein survivin regulates vascular injury. Nature Medicine. 8: 987-94. PMID 12172543 DOI: 10.1038/Nm750 |
0.425 |
|
2002 |
Yu J, Rudic RD, Sessa WC. Nitric oxide-releasing aspirin decreases vascular injury by reducing inflammation and promoting apoptosis. Laboratory Investigation; a Journal of Technical Methods and Pathology. 82: 825-32. PMID 12118084 DOI: 10.1097/01.Lab.0000018828.61722.Bd |
0.753 |
|
2002 |
Pritchard KA, Ackerman AW, Ou J, Curtis M, Smalley DM, Fontana JT, Stemerman MB, Sessa WC. Native low-density lipoprotein induces endothelial nitric oxide synthase dysfunction: role of heat shock protein 90 and caveolin-1. Free Radical Biology & Medicine. 33: 52-62. PMID 12086682 DOI: 10.1016/S0891-5849(02)00851-1 |
0.746 |
|
2002 |
Iwakiri Y, Tsai MH, McCabe TJ, Gratton JP, Fulton D, Groszmann RJ, Sessa WC. Phosphorylation of eNOS initiates excessive NO production in early phases of portal hypertension. American Journal of Physiology. Heart and Circulatory Physiology. 282: H2084-90. PMID 12003815 DOI: 10.1152/Ajpheart.00675.2001 |
0.411 |
|
2002 |
Scotland RS, Morales-Ruiz M, Chen Y, Yu J, Rudic RD, Fulton D, Gratton JP, Sessa WC. Functional reconstitution of endothelial nitric oxide synthase reveals the importance of serine 1179 in endothelium-dependent vasomotion. Circulation Research. 90: 904-10. PMID 11988492 DOI: 10.1161/01.Res.0000016506.04193.96 |
0.779 |
|
2002 |
Fontana J, Fulton D, Chen Y, Fairchild TA, McCabe TJ, Fujita N, Tsuruo T, Sessa WC. Domain mapping studies reveal that the M domain of hsp90 serves as a molecular scaffold to regulate Akt-dependent phosphorylation of endothelial nitric oxide synthase and NO release. Circulation Research. 90: 866-73. PMID 11988487 DOI: 10.1161/01.Res.0000016837.26733.Be |
0.779 |
|
2002 |
Akiyama M, Eguchi D, Weiler D, O'Brien T, Kovesdi I, Scotland RS, Sessa WC, Katusic ZS. Expression and function of recombinant S1179D endothelial nitric oxide synthase in canine cerebral arteries. Stroke. 33: 1071-6. PMID 11935063 DOI: 10.1161/Hs0402.105553 |
0.443 |
|
2002 |
Fulton D, Fontana J, Sowa G, Gratton JP, Lin M, Li KX, Michell B, Kemp BE, Rodman D, Sessa WC. Localization of endothelial nitric-oxide synthase phosphorylated on serine 1179 and nitric oxide in Golgi and plasma membrane defines the existence of two pools of active enzyme. The Journal of Biological Chemistry. 277: 4277-84. PMID 11729179 DOI: 10.1074/Jbc.M106302200 |
0.822 |
|
2002 |
Kim I, Oh JL, Ryu YS, So JN, Sessa WC, Walsh K, Koh GY. Angiopoietin-1 negatively regulates expression and activity of tissue factor in endothelial cells The Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 126-128. PMID 11729102 DOI: 10.1096/Fj.01-0556Fje |
0.467 |
|
2001 |
Sowa G, Pypaert M, Sessa WC. Distinction between signaling mechanisms in lipid rafts vs. caveolae. Proceedings of the National Academy of Sciences of the United States of America. 98: 14072-7. PMID 11707586 DOI: 10.1073/Pnas.241409998 |
0.409 |
|
2001 |
Lee MJ, Thangada S, Paik JH, Sapkota GP, Ancellin N, Chae SS, Wu M, Morales-Ruiz M, Sessa WC, Alessi DR, Hla T. Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis. Molecular Cell. 8: 693-704. PMID 11583630 DOI: 10.1016/S1097-2765(01)00324-0 |
0.403 |
|
2001 |
Paxinou E, Weisse M, Chen Q, Souza JM, Hertkorn C, Selak M, Daikhin E, Yudkoff M, Sowa G, Sessa WC, Ischiropoulos H. Dynamic regulation of metabolism and respiration by endogenously produced nitric oxide protects against oxidative stress. Proceedings of the National Academy of Sciences of the United States of America. 98: 11575-80. PMID 11562476 DOI: 10.1073/Pnas.201293198 |
0.366 |
|
2001 |
Gratton JP, Morales-Ruiz M, Kureishi Y, Fulton D, Walsh K, Sessa WC. Akt down-regulation of p38 signaling provides a novel mechanism of vascular endothelial growth factor-mediated cytoprotection in endothelial cells. The Journal of Biological Chemistry. 276: 30359-65. PMID 11387313 DOI: 10.1074/Jbc.M009698200 |
0.441 |
|
2001 |
Mesri M, Morales-Ruiz M, Ackermann EJ, Bennett CF, Pober JS, Sessa WC, Altieri DC. Suppression of vascular endothelial growth factor-mediated endothelial cell protection by survivin targeting American Journal of Pathology. 158: 1757-1765. PMID 11337373 DOI: 10.1016/S0002-9440(10)64131-4 |
0.45 |
|
2001 |
Fairchild TA, Fulton D, Fontana JT, Gratton JP, McCabe TJ, Sessa WC. Acidic hydrolysis as a mechanism for the cleavage of the Glu(298)-->Asp variant of human endothelial nitric-oxide synthase. The Journal of Biological Chemistry. 276: 26674-9. PMID 11331296 DOI: 10.1074/Jbc.M103647200 |
0.752 |
|
2001 |
Sessa WC. Can modulation of endothelial nitric oxide synthase explain the vasculoprotective actions of statins? Trends in Molecular Medicine. 7: 189-91. PMID 11325618 DOI: 10.1016/S1471-4914(01)01985-2 |
0.363 |
|
2001 |
Morales-Ruiz M, Lee MJ, Zöllner S, Gratton JP, Scotland R, Shiojima I, Walsh K, Hla T, Sessa WC. Sphingosine 1-phosphate activates Akt, nitric oxide production, and chemotaxis through a Gi protein/phosphoinositide 3-kinase pathway in endothelial cells. The Journal of Biological Chemistry. 276: 19672-7. PMID 11278592 DOI: 10.1074/Jbc.M009993200 |
0.454 |
|
2001 |
Pritchard KA, Ackerman AW, Gross ER, Stepp DW, Shi Y, Fontana JT, Baker JE, Sessa WC. Heat shock protein 90 mediates the balance of nitric oxide and superoxide anion from endothelial nitric-oxide synthase. The Journal of Biological Chemistry. 276: 17621-4. PMID 11278264 DOI: 10.1074/Jbc.C100084200 |
0.761 |
|
2001 |
Iwakiri Y, Tsai M, Sessa WC, Groszmann RJ. The phosphorylation of endothelial nitric oxide synthase by Akt increases nitric oxide production in early portal hypertension Gastroenterology. 120: A9. DOI: 10.1016/S0016-5085(08)80044-3 |
0.416 |
|
2000 |
Cao S, Yao J, McCabe TJ, Yao Q, Katusic ZS, Sessa WC, Shah V. Direct interaction between endothelial nitric-oxide synthase and dynamin-2. Implications for nitric-oxide synthase function. The Journal of Biological Chemistry. 276: 14249-56. PMID 11120737 DOI: 10.1074/Jbc.M006258200 |
0.456 |
|
2000 |
Bucci M, Gratton JP, Rudic RD, Acevedo L, Roviezzo F, Cirino G, Sessa WC. In vivo delivery of the caveolin-1 scaffolding domain inhibits nitric oxide synthesis and reduces inflammation. Nature Medicine. 6: 1362-7. PMID 11100121 DOI: 10.1038/82176 |
0.814 |
|
2000 |
Mital S, Zhang X, Zhao G, Bernstein RD, Smith CJ, Fulton DL, Sessa WC, Liao JK, Hintze TH. Simvastatin upregulates coronary vascular endothelial nitric oxide production in conscious dogs American Journal of Physiology - Heart and Circulatory Physiology. 279. PMID 11087217 DOI: 10.1152/Ajpheart.2000.279.6.H2649 |
0.386 |
|
2000 |
Haynes MP, Sinha D, Russell KS, Collinge M, Fulton D, Morales-Ruiz M, Sessa WC, Bender JR. Membrane estrogen receptor engagement activates endothelial nitric oxide synthase via the PI3-kinase-Akt pathway in human endothelial cells Circulation Research. 87: 677-682. PMID 11029403 DOI: 10.1161/01.Res.87.8.677 |
0.465 |
|
2000 |
Kureishi Y, Luo Z, Shiojima I, Bialik A, Fulton D, Lefer DJ, Sessa WC, Walsh K. The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals. Nature Medicine. 6: 1004-10. PMID 10973320 DOI: 10.1038/79510 |
0.509 |
|
2000 |
Bucci M, Roviezzo F, Cicala C, Sessa WC, Cirino G. Geldanamycin, an inhibitor of heat shock protein 90 (Hsp90) mediated signal transduction has anti-inflammatory effects and interacts with glucocorticoid receptor in vivo. British Journal of Pharmacology. 131: 13-6. PMID 10960063 DOI: 10.1038/Sj.Bjp.0703549 |
0.378 |
|
2000 |
Luo Z, Fujio Y, Kureishi Y, Rudic RD, Daumerie G, Fulton D, Sessa WC, Walsh K. Acute modulation of endothelial Akt/PKB activity alters nitric oxide-dependent vasomotor activity in vivo. The Journal of Clinical Investigation. 106: 493-9. PMID 10953024 DOI: 10.1172/Jci9419 |
0.774 |
|
2000 |
Rudic RD, Bucci M, Fulton D, Segal SS, Sessa WC. Temporal events underlying arterial remodeling after chronic flow reduction in mice: correlation of structural changes with a deficit in basal nitric oxide synthesis. Circulation Research. 86: 1160-6. PMID 10850968 DOI: 10.1161/01.Res.86.11.1160 |
0.733 |
|
2000 |
Morales-Ruiz M, Fulton D, Sowa G, Languino LR, Fujio Y, Walsh K, Sessa WC. Vascular endothelial growth factor-stimulated actin reorganization and migration of endothelial cells is regulated via the serine/threonine kinase Akt. Circulation Research. 86: 892-6. PMID 10785512 DOI: 10.1161/01.Res.86.8.892 |
0.473 |
|
2000 |
Gratton JP, Fontana J, O'Connor DS, Garcia-Cardena G, McCabe TJ, Sessa WC. Reconstitution of an endothelial nitric-oxide synthase (eNOS), hsp90, and caveolin-1 complex in vitro. Evidence that hsp90 facilitates calmodulin stimulated displacement of eNOS from caveolin-1. The Journal of Biological Chemistry. 275: 22268-72. PMID 10781589 DOI: 10.1074/Jbc.M001644200 |
0.765 |
|
2000 |
Papapetropoulos A, Fulton D, Mahboubi K, Kalb RG, O'Connor DS, Li F, Altieri DC, Sessa WC. Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway. The Journal of Biological Chemistry. 275: 9102-5. PMID 10734041 DOI: 10.1074/Jbc.275.13.9102 |
0.486 |
|
2000 |
McCabe TJ, Fulton D, Roman LJ, Sessa WC. Enhanced electron flux and reduced calmodulin dissociation may explain 'calcium-independent' eNOS activation by phosphorylation Journal of Biological Chemistry. 275: 6123-6128. PMID 10692402 DOI: 10.1074/Jbc.275.9.6123 |
0.393 |
|
2000 |
Russell KS, Haynes MP, Caulin-Glaser T, Rosneck J, Sessa WC, Bender JR. Estrogen stimulates heat shock protein 90 binding to endothelial nitric oxide synthase in human vascular endothelial cells. Effects on calcium sensitivity and no release Journal of Biological Chemistry. 275: 5026-5030. PMID 10671543 DOI: 10.1074/Jbc.275.7.5026 |
0.475 |
|
2000 |
Fulton D, Papapetropoulos A, Zhang X, Catravas JD, Hintze TH, Sessa WC. Quantification of eNOS mRNA in the canine cardiac vasculature by competitive PCR. American Journal of Physiology. Heart and Circulatory Physiology. 278: H658-65. PMID 10666099 DOI: 10.1152/Ajpheart.2000.278.2.H658 |
0.391 |
|
2000 |
Hungerford JE, Sessa WC, Segal SS. Vasomotor control in arterioles of the mouse cremaster muscle Faseb Journal. 14: 197-207. PMID 10627294 DOI: 10.1096/Fasebj.14.1.197 |
0.376 |
|
2000 |
Cao S, Yao J, McCabe TJ, Yao Q, Sessa WC, McNiven MA, Shah VH, Clin M. Dynamin binds and directly activates endothelial nitric oxide synthase Gastroenterology. 118: A958-A959. DOI: 10.1016/S0016-5085(00)85978-8 |
0.412 |
|
1999 |
Shah V, Wiest R, Garcia-Cardena G, Cadelina G, Groszmann RJ, Sessa WC. Hsp90 regulation of endothelial nitric oxide synthase contributes to vascular control in portal hypertension. American Journal of Physiology. Gastrointestinal and Liver Physiology. 277: G463-G468. PMID 29591697 DOI: 10.1152/Ajpgi.1999.277.2.G463 |
0.463 |
|
1999 |
Papapetropoulos A, Rudic RD, Sessa WC. Molecular control of nitric oxide synthases in the cardiovascular system. Cardiovascular Research. 43: 509-20. PMID 10690323 DOI: 10.1016/S0008-6363(99)00161-3 |
0.72 |
|
1999 |
Shah V, Toruner M, Haddad F, Cadelina G, Papapetropoulos A, Choo K, Sessa WC, Groszmann RJ. Impaired endothelial nitric oxide synthase activity associated with enhanced caveolin binding in experimental cirrhosis in the rat. Gastroenterology. 117: 1222-8. PMID 10535886 DOI: 10.1016/S0016-5085(99)70408-7 |
0.43 |
|
1999 |
Smart EJ, Graf GA, McNiven MA, Sessa WC, Engelman JA, Scherer PE, Okamoto T, Lisanti MP. Caveolins, liquid-ordered domains, and signal transduction. Molecular and Cellular Biology. 19: 7289-304. PMID 10523618 DOI: 10.1128/Mcb.19.11.7289 |
0.349 |
|
1999 |
Segal SS, Brett SE, Sessa WC. Codistribution of NOS and caveolin throughout peripheral vasculature and skeletal muscle of hamsters American Journal of Physiology - Heart and Circulatory Physiology. 277. PMID 10484439 DOI: 10.1152/Ajpheart.1999.277.3.H1167 |
0.367 |
|
1999 |
Sowa G, Liu J, Papapetropoulos A, Rex-Haffner M, Hughes TE, Sessa WC. Trafficking of endothelial nitric-oxide synthase in living cells. Quantitative evidence supporting the role of palmitoylation as a kinetic trapping mechanism limiting membrane diffusion. The Journal of Biological Chemistry. 274: 22524-31. PMID 10428829 DOI: 10.1074/Jbc.274.32.22524 |
0.385 |
|
1999 |
Fulton D, Gratton JP, McCabe TJ, Fontana J, Fujio Y, Walsh K, Franke TF, Papapetropoulos A, Sessa WC. Regulation of endothelium-derived nitric oxide production by the protein kinase Akt. Nature. 399: 597-601. PMID 10376602 DOI: 10.1038/21218 |
0.786 |
|
1999 |
Wiest R, Shah V, Sessa WC, Groszmann RJ. NO overproduction by eNOS precedes hyperdynamic splanchnic circulation in portal hypertensive rats. The American Journal of Physiology. 276: G1043-51. PMID 10198349 DOI: 10.1152/Ajpgi.1999.276.4.G1043 |
0.355 |
|
1999 |
Guillot PV, Guan J, Liu L, Kuivenhoven JA, Rosenberg RD, Sessa WC, Aird WC. A vascular bed-specific pathway. The Journal of Clinical Investigation. 103: 799-805. PMID 10079100 DOI: 10.1172/Jci6017 |
0.424 |
|
1999 |
Rudic RD, Sessa WC. Nitric oxide in endothelial dysfunction and vascular remodeling: clinical correlates and experimental links. American Journal of Human Genetics. 64: 673-7. PMID 10052999 DOI: 10.1086/302304 |
0.743 |
|
1999 |
Malek AM, Jiang L, Lee I, Sessa WC, Izumo S, Alper SL. Induction of nitric oxide synthase mRNA by shear stress requires intracellular calcium and G-protein signals and is modulated by PI 3 kinase. Biochemical and Biophysical Research Communications. 254: 231-42. PMID 9920763 DOI: 10.1006/Bbrc.1998.9921 |
0.375 |
|
1999 |
Moy YP, Sessa WC, Weiss RM. INHIBITION OF ANGIOGENESIS AND TUMOR GROWTH IN HUMAN PROSTATE CANCER LNCaP CELLS WITH THE INHIBITION OF ENDOTHELIAL NITRIC OXIDE The Journal of Urology. 130. DOI: 10.1097/00005392-199904010-00522 |
0.364 |
|
1999 |
Fulton D, Gratton J, McCabe TJ, Fontana J, Fujio Y, Walsh K, Franke TF, Papapetropoulos A, Sessa WC. Erratum: Regulation of endothelium-derived nitric oxide production by the protein kinase Akt Nature. 400: 792-792. DOI: 10.1038/23523 |
0.749 |
|
1998 |
Wang X, Lu M, Gao Y, Papapetropoulos A, Sessa WC, Wang W. Neuronal nitric oxide synthase is expressed in principal cell of collecting duct. American Journal of Physiology. Renal Physiology. 275: F395-F399. PMID 29591686 DOI: 10.1152/Ajprenal.1998.275.3.F395 |
0.331 |
|
1998 |
Sierra-Honigmann MR, Nath AK, Murakami C, García-Cardeña G, Papapetropoulos A, Sessa WC, Madge LA, Schechner JS, Schwabb MB, Polverini PJ, Flores-Riveros JR. Biological action of leptin as an angiogenic factor. Science (New York, N.Y.). 281: 1683-6. PMID 9733517 DOI: 10.1126/Science.281.5383.1683 |
0.388 |
|
1998 |
Presta A, Liu J, Sessa WC, Stuehr DJ. Substrate binding and calmodulin binding to endothelial nitric oxide synthase coregulate its enzymatic activity. Nitric Oxide : Biology and Chemistry. 1: 74-87. PMID 9701047 DOI: 10.1006/Niox.1996.0110 |
0.436 |
|
1998 |
García-Cardeña G, Fan R, Shah V, Sorrentino R, Cirino G, Papapetropoulos A, Sessa WC. Dynamic activation of endothelial nitric oxide synthase by Hsp90 Nature. 392: 821-824. PMID 9580552 DOI: 10.1038/33934 |
0.478 |
|
1998 |
Papapetropoulos A, Piccardoni P, Cirino G, Bucci M, Sorrentino R, Cicala C, Johnson K, Zachariou V, Sessa WC, Altieri DC. Hypotension and inflammatory cytokine gene expression triggered by factor Xa-nitric oxide signaling. Proceedings of the National Academy of Sciences of the United States of America. 95: 4738-42. PMID 9539808 DOI: 10.1073/Pnas.95.8.4738 |
0.4 |
|
1998 |
Rudic RD, Shesely EG, Maeda N, Smithies O, Segal SS, Sessa WC. Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling. The Journal of Clinical Investigation. 101: 731-6. PMID 9466966 DOI: 10.1172/Jci1699 |
0.777 |
|
1997 |
Papapetropoulos A, GarcÃa-Cardeña G, Madri JA, Sessa WC. Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells. The Journal of Clinical Investigation. 100: 3131-9. PMID 9399960 DOI: 10.1172/Jci119868 |
0.484 |
|
1997 |
Shah V, Haddad FG, Garcia-Cardena G, Frangos JA, Mennone A, Groszmann RJ, Sessa WC. Liver sinusoidal endothelial cells are responsible for nitric oxide modulation of resistance in the hepatic sinusoids Journal of Clinical Investigation. 100: 2923-2930. PMID 9389760 DOI: 10.1172/Jci119842 |
0.389 |
|
1997 |
Caulin-Glaser T, García-Cardeña G, Sarrel P, Sessa WC, Bender JR. 17 beta-estradiol regulation of human endothelial cell basal nitric oxide release, independent of cytosolic Ca2+ mobilization. Circulation Research. 81: 885-92. PMID 9351464 DOI: 10.1161/01.Res.81.5.885 |
0.379 |
|
1997 |
García-Cardeña G, Martasek P, Masters BS, Skidd PM, Couet J, Li S, Lisanti MP, Sessa WC. Dissecting the interaction between nitric oxide synthase (NOS) and caveolin. Functional significance of the nos caveolin binding domain in vivo. The Journal of Biological Chemistry. 272: 25437-40. PMID 9325253 DOI: 10.1074/Jbc.272.41.25437 |
0.449 |
|
1997 |
Liu J, Hughes TE, Sessa WC. The first 35 amino acids and fatty acylation sites determine the molecular targeting of endothelial nitric oxide synthase into the Golgi region of cells: a green fluorescent protein study. The Journal of Cell Biology. 137: 1525-35. PMID 9199168 DOI: 10.1083/Jcb.137.7.1525 |
0.397 |
|
1997 |
List BM, Klösch B, Völker C, Gorren AC, Sessa WC, Werner ER, Kukovetz WR, Schmidt K, Mayer B. Characterization of bovine endothelial nitric oxide synthase as a homodimer with down-regulated uncoupled NADPH oxidase activity: tetrahydrobiopterin binding kinetics and role of haem in dimerization. The Biochemical Journal. 323: 159-65. PMID 9173876 DOI: 10.1042/Bj3230159 |
0.347 |
|
1997 |
Papapetropoulos A, Desai KM, Rudic RD, Mayer B, Zhang R, Ruiz-Torres MP, García-Cardeña G, Madri JA, Sessa WC. Nitric oxide synthase inhibitors attenuate transforming-growth-factor-beta 1-stimulated capillary organization in vitro. The American Journal of Pathology. 150: 1835-44. PMID 9137106 |
0.684 |
|
1997 |
Wheeler MA, Smith SD, GarcÃa-Cardeña G, Nathan CF, Weiss RM, Sessa WC. Bacterial infection induces nitric oxide synthase in human neutrophils. The Journal of Clinical Investigation. 99: 110-6. PMID 9011564 DOI: 10.1172/Jci119121 |
0.365 |
|
1996 |
García-Cardeña G, Fan R, Stern DF, Liu J, Sessa WC. Endothelial nitric oxide synthase is regulated by tyrosine phosphorylation and interacts with caveolin-1. The Journal of Biological Chemistry. 271: 27237-40. PMID 8910295 DOI: 10.1074/Jbc.271.44.27237 |
0.455 |
|
1996 |
Liu J, García-Cardeña G, Sessa WC. Palmitoylation of endothelial nitric oxide synthase is necessary for optimal stimulated release of nitric oxide: implications for caveolae localization. Biochemistry. 35: 13277-81. PMID 8873592 DOI: 10.1021/Bi961720E |
0.401 |
|
1996 |
Reid SN, Daw NW, Czepita D, Flavin HJ, Sessa WC. Inhibition of nitric oxide synthase does not alter ocular dominance shifts in kitten visual cortex. The Journal of Physiology. 494: 511-7. PMID 8842008 DOI: 10.1113/Jphysiol.1996.Sp021509 |
0.308 |
|
1996 |
García-Cardeña G, Oh P, Liu J, Schnitzer JE, Sessa WC. Targeting of nitric oxide synthase to endothelial cell caveolae via palmitoylation: implications for nitric oxide signaling. Proceedings of the National Academy of Sciences of the United States of America. 93: 6448-53. PMID 8692835 DOI: 10.1073/Pnas.93.13.6448 |
0.443 |
|
1996 |
Martasek P, Liu Q, Liu J, Roman LJ, Gross SS, Sessa WC, Masters BSS. Characterization of bovine endothelial nitric oxide synthase expressed in E. coli Biochemical and Biophysical Research Communications. 219: 359-365. PMID 8604992 DOI: 10.1006/Bbrc.1996.0238 |
0.35 |
|
1996 |
Smith CJ, Sun D, Hoegler C, Roth BS, Zhang X, Zhao G, Xu XB, Kobari Y, Pritchard K, Sessa WC, Hintze TH. Reduced gene expression of vascular endothelial NO synthase and cyclooxygenase-1 in heart failure. Circulation Research. 78: 58-64. PMID 8603506 DOI: 10.1161/01.Res.78.1.58 |
0.345 |
|
1996 |
Du W, Wang X, Sessa W, Yano Y, Sumpio B. Cyclic strain regulation of endothelial cell biology: Genes, signals & functions Cardiovascular Pathology. 5: 288. DOI: 10.1016/1054-8807(96)80366-8 |
0.364 |
|
1995 |
Liu J, García-Cardeña G, Sessa WC. Biosynthesis and palmitoylation of endothelial nitric oxide synthase: mutagenesis of palmitoylation sites, cysteines-15 and/or -26, argues against depalmitoylation-induced translocation of the enzyme. Biochemistry. 34: 12333-40. PMID 7547976 DOI: 10.1021/Bi00038A029 |
0.365 |
|
1995 |
Awolesi MA, Sessa WC, Sumpio BE. Cyclic strain upregulates nitric oxide synthase in cultured bovine aortic endothelial cells. The Journal of Clinical Investigation. 96: 1449-54. PMID 7544806 DOI: 10.1172/Jci118181 |
0.347 |
|
1995 |
Pritchard KA, Groszek L, Smalley DM, Sessa WC, Wu M, Villalon P, Wolin MS, Stemerman MB. Native low-density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion Circulation Research. 77: 510-518. PMID 7543827 DOI: 10.1161/01.Res.77.3.510 |
0.364 |
|
1995 |
Sessa WC, García-Cardeña G, Liu J, Keh A, Pollock JS, Bradley J, Thiru S, Braverman IM, Desai KM. The Golgi association of endothelial nitric oxide synthase is necessary for the efficient synthesis of nitric oxide. The Journal of Biological Chemistry. 270: 17641-4. PMID 7543089 DOI: 10.1074/Jbc.270.30.17641 |
0.464 |
|
1995 |
Zhang R, Min W, Sessa WC. Functional analysis of the human endothelial nitric oxide synthase promoter. Sp1 and GATA factors are necessary for basal transcription in endothelial cells. The Journal of Biological Chemistry. 270: 15320-6. PMID 7541039 DOI: 10.1074/Jbc.270.25.15320 |
0.332 |
|
1995 |
SHEN W, ZHANG X, ZHAO G, WOLIN MS, SESSA W, HINTZE TH. Nitric oxide production and NO synthase gene expression contribute to vascular regulation during exercise Medicine & Science in Sports & Exercise. 27: 1125???1134. DOI: 10.1249/00005768-199508000-00005 |
0.387 |
|
1994 |
Rosenkranz-Weiss P, Sessa WC, Milstien S, Kaufman S, Watson CA, Pober JS. Regulation of Nitric Oxide Synthesis by Proinflammatory Cytokines in Human Umbilical Vein Endothelial Cells: Elevations in Tetrahydrobiopterin Levels Enhance Endothelial Nitric Oxide Synthase Specific Activity Journal of Clinical Investigation. 93: 2236-2243. PMID 7514193 DOI: 10.1172/Jci117221 |
0.42 |
|
1994 |
Sessa WC. The nitric oxide synthase family of proteins. Journal of Vascular Research. 31: 131-43. PMID 7511942 DOI: 10.1159/000159039 |
0.391 |
|
1994 |
Sessa WC, Pritchard K, Seyedi N, Wang J, Hintze TH. Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression. Circulation Research. 74: 349-53. PMID 7507417 DOI: 10.1161/01.Res.74.2.349 |
0.339 |
|
1993 |
Escalante B, Omata K, Sessa W, Lee SG, Falck JR, Schwartzman ML. 20-Hydroxyeicosatetraenoic acid is an endothelium-dependent vasoconstrictor in rabbit arteries European Journal of Pharmacology. 235: 1-7. PMID 8519270 DOI: 10.1016/0014-2999(93)90812-V |
0.381 |
|
1993 |
Sessa WC, Harrison JK, Luthin DR, Pollock JS, Lynch KR. Genomic analysis and expression patterns reveal distinct genes for endothelial and brain nitric oxide synthase. Hypertension (Dallas, Tex. : 1979). 21: 934-8. PMID 7685005 DOI: 10.1161/01.Hyp.21.6.934 |
0.345 |
|
1993 |
Sessa WC, Barber CM, Lynch KR. Mutation of N-myristoylation site converts endothelial cell nitric oxide synthase from a membrane to a cytosolic protein Circulation Research. 72: 921-924. PMID 7680289 DOI: 10.1161/01.Res.72.4.921 |
0.346 |
|
1992 |
Hecker M, Siegle I, MacArthur H, Sessa WC, Vane JR. Role of intracellular thiols in release of EDRF from cultured endothelial cells American Journal of Physiology - Heart and Circulatory Physiology. 262. PMID 1558197 DOI: 10.1152/Ajpheart.1992.262.3.H888 |
0.371 |
|
1991 |
Hecker M, Mitchell JA, Swierkosz TA, Sessa WC, Vane JR. Inhibition by L-glutamine of the release of endothelium-derived relaxing factor from cultured endothelial cells. British Journal of Pharmacology. 101: 237-9. PMID 2257431 DOI: 10.1111/J.1476-5381.1990.Tb12693.X |
0.307 |
|
1991 |
Pagano PJ, Lin L, Sessa WC, Nasjletti A. Arachidonic acid elicits endothelium-dependent release from the rabbit aorta of a constrictor prostanoid resembling prostaglandin endoperoxides. Circulation Research. 69: 396-405. PMID 1907227 DOI: 10.1161/01.Res.69.2.396 |
0.605 |
|
1991 |
Desai KM, Zembowicz A, Sessa WC, Vane JR. Nitroxergic nerves mediate vagally induced relaxation in the isolated stomach of the guinea pig. Proceedings of the National Academy of Sciences of the United States of America. 88: 11490-4. PMID 1684865 DOI: 10.1073/Pnas.88.24.11490 |
0.304 |
|
1991 |
Hecker M, Sessa WC, Mitchell JA, Änggård EE, Vane JR. The Biosynthesis of Endothelium-Derived Relaxing Factor by Endothelial Cells as a Means of Removing Excess Nitrogen Journal of Cardiovascular Pharmacology. 17: S19-S24. DOI: 10.1097/00005344-199117003-00005 |
0.338 |
|
1990 |
Sessa WC, Nasjletti A. Dexamethasone selectively attenuates prostanoid-induced vasoconstrictor responses in vitro. Circulation Research. 66: 383-8. PMID 2297809 DOI: 10.1161/01.Res.66.2.383 |
0.604 |
|
1990 |
Hecker M, Sessa WC, Harris HJ, Anggård EE, Vane JR. The metabolism of L-arginine and its significance for the biosynthesis of endothelium-derived relaxing factor: cultured endothelial cells recycle L-citrulline to L-arginine. Proceedings of the National Academy of Sciences of the United States of America. 87: 8612-6. PMID 2236071 DOI: 10.1073/Pnas.87.21.8612 |
0.307 |
|
1990 |
Sessa WC, Halushka PV, Okwu A, Nasjletti A. Characterization of the vascular thromboxane A2/prostaglandin endoperoxide receptor in rabbit aorta. Regulation by dexamethasone. Circulation Research. 67: 1562-9. PMID 2147131 DOI: 10.1161/01.Res.67.6.1562 |
0.607 |
|
1990 |
Sessa WC, Lin L, Nasjletti A. Reciprocal effects of dexamethasone on vasodilatory responses to arachidonic acid and prostanoids in the isolated perfused rabbit kidney. Hypertension (Dallas, Tex. : 1979). 15: I93-6. PMID 2105268 DOI: 10.1161/01.Hyp.15.2_Suppl.I93 |
0.535 |
|
1990 |
Escalante B, Sessa WC, Falck JR, Yadagiri P, Schwartzman ML. Cytochrome P450-dependent arachidonic acid metabolites, 19- and 20-hydroxyeicosatetraenoic acids, enhance sodium-potassium ATPase activity in vascular smooth muscle Journal of Cardiovascular Pharmacology. 16: 438-443. PMID 1700215 DOI: 10.1097/00005344-199009000-00013 |
0.337 |
|
1987 |
Mullane K, Hatala MA, Kraemer R, Sessa W, Westlin W. Myocardial salvage induced by REV-5901: an inhibitor and antagonist of the leukotrienes. Journal of Cardiovascular Pharmacology. 10: 398-406. PMID 2444792 DOI: 10.1097/00005344-198710000-00004 |
0.31 |
|
1985 |
Rodgers RL, Breault PH, Sessa WC, Chichester CO. Depressor effect of diabetes in spontaneously hypertensive rat: role of vascular reactivity and prolyl hydroxylase and lysyl oxidase activities. Life Sciences. 37: 2237-47. PMID 2866437 DOI: 10.1016/0024-3205(85)90014-1 |
0.305 |
|
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