Peter R. Arvan - Publications

Affiliations: 
1988- Harvard Medical School, Boston, MA, United States 
 1996-2003 Yeshiva University, New York, NY, United States 
 2003-1988 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Cell Biology, Molecular Biology, Biochemistry
Website:
https://www.uofmhealth.org/profile/872/peter-r-arvan-md-phd

91 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Tran DT, Pottekat A, Mir SA, Loguercio S, Jang I, Campos AR, Scully KM, Lahmy R, Liu M, Arvan P, Balch WE, Kaufman RJ, Itkin-Ansari P. Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role For Peroxiredoxin 4 in Proinsulin Folding. Diabetes. PMID 32457219 DOI: 10.2337/db20-0245  1
2020 Carrat GR, Haythorne E, Tomas A, Haataja L, Müller A, Arvan P, Piunti A, Cheng K, Huang M, Pullen TJ, Georgiadou E, Stylianides T, Amirruddin NS, Salem V, Distaso W, et al. The type 2 diabetes gene product STARD10 is a phosphoinositide binding protein that controls insulin secretory granule biogenesis. Molecular Metabolism. 101015. PMID 32416313 DOI: 10.1016/j.molmet.2020.101015  1
2020 Shrestha N, Liu T, Ji Y, Reinert R, Torres M, Li X, Zhang M, Tang CA, Hu CA, Liu C, Naji A, Liu M, Lin JD, Kersten S, Arvan P, et al. Sel1L-Hrd1 ER-associated degradation maintains β-cell identity via TGFβ signaling. The Journal of Clinical Investigation. PMID 32182217 DOI: 10.1172/JCI134874  1
2020 Sun J, Xiong Y, Li X, Haataja L, Chen W, Mir SA, Lv L, Madley R, Larkin D, Anjum A, Dhayalan B, Rege N, Wickramasinghe ND, Weiss MA, Itkin-Ansari P, ... ... Arvan P, et al. Role of Proinsulin Self-Association in Mutant gene-induced Diabetes of Youth. Diabetes. PMID 32139596 DOI: 10.2337/db19-1106  1
2020 Rege NK, Liu M, Dhayalan B, Chen YS, Smith NA, Rahimi L, Sun J, Guo H, Yang Y, Haataja L, Phillips NFB, Whittaker J, Smith BJ, Arvan P, Ismail-Beigi F, et al. "Register-shift" insulin analogs uncover constraints of proteotoxicity in protein evolution. The Journal of Biological Chemistry. PMID 32005662 DOI: 10.1074/jbc.RA119.011389  1
2019 Li X, Itani OA, Haataja L, Dumas KJ, Yang J, Cha J, Flibotte S, Shih HJ, Delaney CE, Xu J, Qi L, Arvan P, Liu M, Hu PJ. Requirement for translocon-associated protein (TRAP) α in insulin biogenesis. Science Advances. 5: eaax0292. PMID 31840061 DOI: 10.1126/sciadv.aax0292  1
2019 Sims EK, Syed F, Nyalwidhe J, Bahnson HT, Haataja L, Speake C, Morris MA, Balamurugan AN, Mirmira RG, Nadler J, Mastracci TL, Arvan P, Greenbaum CJ, Evans-Molina C. Abnormalities in proinsulin processing in islets from individuals with longstanding T1D. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 31442418 DOI: 10.1016/j.trsl.2019.08.001  1
2019 Jang I, Pottekat A, Poothong J, Yong J, Lagunas-Acosta J, Charbono A, Chen Z, Scheuner DL, Liu M, Itkin-Ansari P, Arvan P, Kaufman RJ. PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity. Elife. 8. PMID 31184304 DOI: 10.7554/eLife.44528  1
2019 Arunagiri A, Haataja L, Pottekat A, Pamenan F, Kim S, Zeltser LM, Paton AW, Paton JC, Tsai B, Itkin-Ansari P, Kaufman RJ, Liu M, Arvan P. Proinsulin misfolding is an early event in the progression to type 2 diabetes. Elife. 8. PMID 31184302 DOI: 10.7554/eLife.44532  1
2019 Sims EK, Bahnson HT, Nyalwidhe J, Haataja L, Davis AK, Speake C, DiMeglio LA, Blum J, Morris MA, Mirmira RG, Nadler J, Mastracci TL, Marcovina S, Qian WJ, Yi L, ... ... Arvan P, et al. Response to Comment on Sims et al. Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes. Diabetes Care 2019;42:258-264. Diabetes Care. 42: e85-e86. PMID 31010952 DOI: 10.2337/dci19-0012  1
2019 Mojtaba Ghiasi S, Dahlby T, Hede Andersen C, Haataja L, Petersen S, Omar-Hmeadi M, Yang M, Pihl C, Emilie Bresson S, Saad Khilji M, Klindt K, Cheta O, Perone MJ, Tyrberg B, Prats C, ... ... Arvan P, et al. The Endoplasmic Reticulum Chaperone Glucose-Regulated Protein 94 is Essential for Proinsulin Handling. Diabetes. PMID 30670477 DOI: 10.2337/db18-0671  1
2018 Liu M, Weiss MA, Arunagiri A, Yong J, Rege N, Sun J, Haataja L, Kaufman RJ, Arvan P. Biosynthesis, structure, and folding of the insulin precursor protein. Diabetes, Obesity & Metabolism. 20: 28-50. PMID 30230185 DOI: 10.1111/dom.13378  1
2018 Taneera J, Prasad RB, Dhaiban S, Mohammed AK, Haataja L, Arvan P, Hamad M, Groop L, Wollheim CB. Silencing of the FTO gene inhibits insulin secretion: An in vitro study using GRINCH cells. Molecular and Cellular Endocrinology. PMID 29890211 DOI: 10.1016/j.mce.2018.06.003  1
2018 Hussain SS, Harris MT, Kreutzberger AJB, Inouye CM, Doyle CA, Castle AM, Arvan P, Castle JD. Control of Insulin Granule Formation and Function by the ABC Transporters ABCG1 and ABCA1 and by Oxysterol Binding Protein OSBP. Molecular Biology of the Cell. PMID 29540530 DOI: 10.1091/mbc.E17-08-0519  1
2018 Kim GH, Shi G, Somlo DR, Haataja L, Song S, Long Q, Nillni EA, Low MJ, Arvan P, Myers MG, Qi L. Hypothalamic ER-associated degradation regulates POMC maturation, feeding, and age-associated obesity. The Journal of Clinical Investigation. PMID 29457782 DOI: 10.1172/JCI96420  1
2018 Arunagiri A, Haataja L, Cunningham CN, Shrestha N, Tsai B, Qi L, Liu M, Arvan P. Misfolded proinsulin in the endoplasmic reticulum during development of beta cell failure in diabetes. Annals of the New York Academy of Sciences. PMID 29377149 DOI: 10.1111/nyas.13531  1
2017 Guo H, Sun J, Li X, Xiong Y, Wang H, Shu H, Zhu R, Liu Q, Huang Y, Madley R, Wang Y, Cui J, Arvan P, Liu M. Positive charge in the n-region of the signal peptide contributes to efficient post-translational translocation of small secretory preproteins. The Journal of Biological Chemistry. PMID 29229776 DOI: 10.1074/jbc.RA117.000922  1
2017 Wasserfall C, Nick HS, Campbell-Thompson M, Beachy D, Haataja L, Kusmartseva I, Posgai A, Beery M, Rhodes C, Bonifacio E, Arvan P, Atkinson M. Persistence of Pancreatic Insulin mRNA Expression and Proinsulin Protein in Type 1 Diabetes Pancreata. Cell Metabolism. 26: 568-575.e3. PMID 28877460 DOI: 10.1016/j.cmet.2017.08.013  1
2016 Barbetti F, Colombo C, Haataja L, Cras-Méneur C, Bernardini S, Arvan P. Hyperglucagonemia in an animal model of insulin- deficient diabetes: what therapy can improve it? Clinical Diabetes and Endocrinology. 2: 11. PMID 28702245 DOI: 10.1186/s40842-016-0029-5  1
2016 Riahi Y, Wikstrom JD, Bachar-Wikstrom E, Polin N, Zucker H, Lee MS, Quan W, Haataja L, Liu M, Arvan P, Cerasi E, Leibowitz G. Erratum to: Autophagy is a major regulator of beta cell insulin homeostasis. Diabetologia. PMID 27189065 DOI: 10.1007/s00125-016-3986-4  1
2016 Riahi Y, Wikstrom JD, Bachar-Wikstrom E, Polin N, Zucker H, Lee MS, Quan W, Haataja L, Liu M, Arvan P, Cerasi E, Leibowitz G. Autophagy is a major regulator of beta cell insulin homeostasis. Diabetologia. PMID 26831301 DOI: 10.1007/s00125-016-3868-9  1
2016 Haataja L, Manickam N, Soliman A, Tsai B, Liu M, Arvan P. Disulfide Mispairing During Proinsulin Folding in the Endoplasmic Reticulum. Diabetes. PMID 26822090 DOI: 10.2337/db15-1345  1
2015 Alejandro EU, Bozadjieva N, Kumusoglu D, Abdulhamid S, Levine H, Haataja L, Vadrevu S, Satin LS, Arvan P, Bernal-Mizrachi E. Disruption of O-linked N-Acetylglucosamine Signaling Induces ER Stress and β Cell Failure. Cell Reports. PMID 26673325 DOI: 10.1016/j.celrep.2015.11.020  1
2015 Zhu S, Larkin D, Lu S, Inouye C, Haataja L, Anjum A, Kennedy R, Castle D, Arvan P. Monitoring C-peptide Storage and Secretion in Islet Beta Cells in vitro and in vivo. Diabetes. PMID 26647386 DOI: 10.2337/db15-1264  1
2015 Gao XH, Krokowski D, Guan BJ, Bederman I, Majumder M, Parisien M, Diatchenko L, Kabil O, Willard B, Banerjee R, Wang B, Bebek G, Evans CR, Fox PL, Gerson SL, ... ... Arvan P, et al. Quantitative H2S-mediated protein sulfhydration reveals metabolic reprogramming during the Integrated Stress Response. Elife. 4. PMID 26595448 DOI: 10.7554/eLife.10067  1
2015 Cui J, Chen W, Sun J, Guo H, Madley R, Xiong Y, Pan X, Wang H, Tai AW, Weiss MA, Arvan P, Liu M. Competitive inhibition of the endoplasmic reticulum signal peptidase by non-cleavable mutant preprotein cargos. The Journal of Biological Chemistry. PMID 26446786 DOI: 10.1074/jbc.M115.692350  1
2015 Sharma RB, O'Donnell AC, Stamateris RE, Ha B, McCloskey KM, Reynolds PR, Arvan P, Alonso LC. Insulin demand regulates β cell number via the unfolded protein response. The Journal of Clinical Investigation. PMID 26389675 DOI: 10.1172/JCI79264  1
2015 Alarcon C, Boland BB, Uchizono Y, Moore PC, Peterson B, Rajan S, Rhodes OS, Noske AB, Haataja L, Arvan P, Marsh BJ, Austin J, Rhodes CJ. Pancreatic ß-Cell Adaptive Plasticity in Obesity Increases Insulin Production but Adversely Affects Secretory Function. Diabetes. PMID 26307586 DOI: 10.2337/db15-0792  1
2015 He K, Cunningham C, Manickam N, Liu M, Arvan P, Tsai B. PDI Reductase Acts on Akita Mutant Proinsulin to Initiate Retro-translocation Along the Hrd1/Sel1L-p97 Axis. Molecular Biology of the Cell. PMID 26269577 DOI: 10.1091/mbc.E15-01-0034  1
2015 Russ HA, Parent AV, Ringler JJ, Hennings TG, Nair GG, Shveygert M, Guo T, Puri S, Haataja L, Cirulli V, Blelloch R, Szot GL, Arvan P, Hebrok M. Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro. The Embo Journal. 34: 1759-72. PMID 25908839 DOI: 10.15252/embj.201591058  1
2015 Arvan P, Bernal-Mizrachi E, Liu M, Pietropaolo M, Satin L, Schnell S, Soleimanpour SA. Molecular aspects of pancreatic beta cell failure and diabetes. Molecular Aspects of Medicine. 42: 1-2. PMID 25596327 DOI: 10.1016/j.mam.2015.01.002  1
2015 Sun J, Cui J, He Q, Chen Z, Arvan P, Liu M. Proinsulin misfolding and endoplasmic reticulum stress during the development and progression of diabetes. Molecular Aspects of Medicine. 42: 105-18. PMID 25579745 DOI: 10.1016/j.mam.2015.01.001  1
2015 Liu M, Sun J, Cui J, Chen W, Guo H, Barbetti F, Arvan P. INS-gene mutations: from genetics and beta cell biology to clinical disease. Molecular Aspects of Medicine. 42: 3-18. PMID 25542748 DOI: 10.1016/j.mam.2014.12.001  1
2014 Alejandro EU, Gregg B, Wallen T, Kumusoglu D, Meister D, Chen A, Merrins MJ, Satin LS, Liu M, Arvan P, Bernal-Mizrachi E. Maternal diet-induced microRNAs and mTOR underlie β cell dysfunction in offspring. The Journal of Clinical Investigation. 124: 4395-410. PMID 25180600 DOI: 10.1172/JCI74237  1
2014 Jonatan D, Spence JR, Method AM, Kofron M, Sinagoga K, Haataja L, Arvan P, Deutsch GH, Wells JM. Sox17 regulates insulin secretion in the normal and pathologic mouse β cell. Plos One. 9: e104675. PMID 25144761 DOI: 10.1371/journal.pone.0104675  1
2014 Prabhu Y, Blanco EH, Liu M, Peinado JR, Wheeler MC, Gekakis N, Arvan P, Lindberg I. Defective transport of the obesity mutant PC1/3 N222D contributes to loss of function. Endocrinology. 155: 2391-401. PMID 24828610 DOI: 10.1210/en.2013-1985  1
2014 Guo H, Xiong Y, Witkowski P, Cui J, Wang LJ, Sun J, Lara-Lemus R, Haataja L, Hutchison K, Shan SO, Arvan P, Liu M. Inefficient translocation of preproinsulin contributes to pancreatic β cell failure and late-onset diabetes. The Journal of Biological Chemistry. 289: 16290-302. PMID 24770419 DOI: 10.1074/jbc.M114.562355  1
2014 Liu M, Wright J, Guo H, Xiong Y, Arvan P. Proinsulin entry and transit through the endoplasmic reticulum in pancreatic beta cells. Vitamins and Hormones. 95: 35-62. PMID 24559913 DOI: 10.1016/B978-0-12-800174-5.00002-8  1
2013 Gualeni B, Rajpar MH, Kellogg A, Bell PA, Arvan P, Boot-Handford RP, Briggs MD. A novel transgenic mouse model of growth plate dysplasia reveals that decreased chondrocyte proliferation due to chronic ER stress is a key factor in reduced bone growth. Disease Models & Mechanisms. 6: 1414-25. PMID 24046357 DOI: 10.1242/dmm.013342  1
2013 Wright J, Birk J, Haataja L, Liu M, Ramming T, Weiss MA, Appenzeller-Herzog C, Arvan P. Endoplasmic reticulum oxidoreductin-1α (Ero1α) improves folding and secretion of mutant proinsulin and limits mutant proinsulin-induced endoplasmic reticulum stress. The Journal of Biological Chemistry. 288: 31010-8. PMID 24022479 DOI: 10.1074/jbc.M113.510065  1
2013 Ferris SP, Jaber NS, Molinari M, Arvan P, Kaufman RJ. UDP-glucose:glycoprotein glucosyltransferase (UGGT1) promotes substrate solubility in the endoplasmic reticulum. Molecular Biology of the Cell. 24: 2597-608. PMID 23864712 DOI: 10.1091/mbc.E13-02-0101  1
2013 Wright J, Wang X, Haataja L, Kellogg AP, Lee J, Liu M, Arvan P. Dominant protein interactions that influence the pathogenesis of conformational diseases. The Journal of Clinical Investigation. 123: 3124-34. PMID 23722904 DOI: 10.1172/JCI67260  1
2013 Krokowski D, Han J, Saikia M, Majumder M, Yuan CL, Guan BJ, Bevilacqua E, Bussolati O, Bröer S, Arvan P, Tchórzewski M, Snider MD, Puchowicz M, Croniger CM, Kimball SR, et al. A self-defeating anabolic program leads to β-cell apoptosis in endoplasmic reticulum stress-induced diabetes via regulation of amino acid flux. The Journal of Biological Chemistry. 288: 17202-13. PMID 23645676 DOI: 10.1074/jbc.M113.466920  1
2013 Haataja L, Snapp E, Wright J, Liu M, Hardy AB, Wheeler MB, Markwardt ML, Rizzo M, Arvan P. Proinsulin intermolecular interactions during secretory trafficking in pancreatic β cells. The Journal of Biological Chemistry. 288: 1896-906. PMID 23223446 DOI: 10.1074/jbc.M112.420018  1
2012 Arvan P, Pietropaolo M, Ostrov D, Rhodes CJ. Islet autoantigens: structure, function, localization, and regulation. Cold Spring Harbor Perspectives in Medicine. 2. PMID 22908193 DOI: 10.1101/cshperspect.a007658  1
2012 Liu M, Lara-Lemus R, Shan SO, Wright J, Haataja L, Barbetti F, Guo H, Larkin D, Arvan P. Impaired cleavage of preproinsulin signal peptide linked to autosomal-dominant diabetes. Diabetes. 61: 828-37. PMID 22357960 DOI: 10.2337/db11-0878  1
2012 Rajpal G, Schuiki I, Liu M, Volchuk A, Arvan P. Action of protein disulfide isomerase on proinsulin exit from endoplasmic reticulum of pancreatic β-cells. The Journal of Biological Chemistry. 287: 43-7. PMID 22105075 DOI: 10.1074/jbc.C111.279927  1
2012 Atkinson MA, Bluestone JA, Eisenbarth GS, Hebrok M, Herold KC, Accili D, Pietropaolo M, Arvan PR, Von Herrath M, Markel DS, Rhodes CJ. How does type 1 diabetes develop? The notion of homicide or β-cell suicide revisited (Diabetes (2011) 60, (1370-1379)) Diabetes. 61: 1648. DOI: 10.2337/db12-er06a  1
2011 Hodish I, Absood A, Liu L, Liu M, Haataja L, Larkin D, Al-Khafaji A, Zaki A, Arvan P. In vivo misfolding of proinsulin below the threshold of frank diabetes. Diabetes. 60: 2092-101. PMID 21677281 DOI: 10.2337/db10-1671  1
2011 Khoo C, Yang J, Rajpal G, Wang Y, Liu J, Arvan P, Stoffers DA. Endoplasmic reticulum oxidoreductin-1-like β (ERO1lβ) regulates susceptibility to endoplasmic reticulum stress and is induced by insulin flux in β-cells. Endocrinology. 152: 2599-608. PMID 21540283 DOI: 10.1210/en.2010-1420  1
2011 Atkinson MA, Bluestone JA, Eisenbarth GS, Hebrok M, Herold KC, Accili D, Pietropaolo M, Arvan PR, Von Herrath M, Markel DS, Rhodes CJ. How does type 1 diabetes develop?: the notion of homicide or β-cell suicide revisited. Diabetes. 60: 1370-9. PMID 21525508 DOI: 10.2337/db10-1797  1
2010 Liu M, Haataja L, Wright J, Wickramasinghe NP, Hua QX, Phillips NF, Barbetti F, Weiss MA, Arvan P. Mutant INS-gene induced diabetes of youth: proinsulin cysteine residues impose dominant-negative inhibition on wild-type proinsulin transport. Plos One. 5: e13333. PMID 20948967 DOI: 10.1371/journal.pone.0013333  1
2010 Liu M, Hodish I, Haataja L, Lara-Lemus R, Rajpal G, Wright J, Arvan P. Proinsulin misfolding and diabetes: mutant INS gene-induced diabetes of youth. Trends in Endocrinology and Metabolism: Tem. 21: 652-9. PMID 20724178 DOI: 10.1016/j.tem.2010.07.001  1
2010 Liu M, Hua QX, Hu SQ, Jia W, Yang Y, Saith SE, Whittaker J, Arvan P, Weiss MA. Deciphering the hidden informational content of protein sequences: foldability of proinsulin hinges on a flexible arm that is dispensable in the mature hormone. The Journal of Biological Chemistry. 285: 30989-1001. PMID 20663888 DOI: 10.1074/jbc.M110.152645  1
2010 Peteiro-Gonzalez D, Lee J, Rodriguez-Fontan J, Castro-Piedras I, Cameselle-Teijeiro J, Beiras A, Bravo SB, Alvarez CV, Hardy DM, Targovnik HM, Arvan P, Lado-Abeal J. New insights into thyroglobulin pathophysiology revealed by the study of a family with congenital goiter. The Journal of Clinical Endocrinology and Metabolism. 95: 3522-6. PMID 20410234 DOI: 10.1210/jc.2009-2109  1
2010 Sohma Y, Hua QX, Liu M, Phillips NB, Hu SQ, Whittaker J, Whittaker LJ, Ng A, Roberts CT, Arvan P, Kent SB, Weiss MA. Contribution of residue B5 to the folding and function of insulin and IGF-I: constraints and fine-tuning in the evolution of a protein family. The Journal of Biological Chemistry. 285: 5040-55. PMID 19959476 DOI: 10.1074/jbc.M109.062992  1
2010 Hodish I, Liu M, Rajpal G, Larkin D, Holz RW, Adams A, Liu L, Arvan P. Misfolded proinsulin affects bystander proinsulin in neonatal diabetes. The Journal of Biological Chemistry. 285: 685-94. PMID 19880509 DOI: 10.1074/jbc.M109.038042  1
2009 Liu M, Wan ZL, Chu YC, Aladdin H, Klaproth B, Choquette M, Hua QX, Mackin RB, Rao JS, De Meyts P, Katsoyannis PG, Arvan P, Weiss MA. Crystal structure of a "nonfoldable" insulin: impaired folding efficiency despite native activity. The Journal of Biological Chemistry. 284: 35259-72. PMID 19850922 DOI: 10.1074/jbc.M109.046888  1
2009 Rajpar MH, McDermott B, Kung L, Eardley R, Knowles L, Heeran M, Thornton DJ, Wilson R, Bateman JF, Poulsom R, Arvan P, Kadler KE, Briggs MD, Boot-Handford RP. Targeted induction of endoplasmic reticulum stress induces cartilage pathology. Plos Genetics. 5: e1000691. PMID 19834559 DOI: 10.1371/journal.pgen.1000691  1
2009 Nicolson TJ, Bellomo EA, Wijesekara N, Loder MK, Baldwin JM, Gyulkhandanyan AV, Koshkin V, Tarasov AI, Carzaniga R, Kronenberger K, Taneja TK, da Silva Xavier G, Libert S, Froguel P, Scharfmann R, ... ... Arvan P, et al. Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants. Diabetes. 58: 2070-83. PMID 19542200 DOI: 10.2337/db09-0551  1
2009 Rajpal G, Liu M, Zhang Y, Arvan P. Single-chain insulins as receptor agonists. Molecular Endocrinology (Baltimore, Md.). 23: 679-88. PMID 19228795 DOI: 10.1210/me.2008-0349  1
2008 Colombo C, Porzio O, Liu M, Massa O, Vasta M, Salardi S, Beccaria L, Monciotti C, Toni S, Pedersen O, Hansen T, Federici L, Pesavento R, Cadario F, Federici G, ... ... Arvan P, et al. Seven mutations in the human insulin gene linked to permanent neonatal/infancy-onset diabetes mellitus. The Journal of Clinical Investigation. 118: 2148-56. PMID 18451997 DOI: 10.1172/JCI33777  1
2008 Yamaguchi Y, Larkin D, Lara-Lemus R, Ramos-Castañeda J, Liu M, Arvan P. Endoplasmic reticulum (ER) chaperone regulation and survival of cells compensating for deficiency in the ER stress response kinase, PERK. The Journal of Biological Chemistry. 283: 17020-9. PMID 18426796 DOI: 10.1074/jbc.M802466200  1
2008 Kim PS, Lee J, Jongsamak P, Menon S, Li B, Hossain SA, Bae JH, Panijpan B, Arvan P. Defective protein folding and intracellular retention of thyroglobulin-R19K mutant as a cause of human congenital goiter. Molecular Endocrinology (Baltimore, Md.). 22: 477-84. PMID 17916655 DOI: 10.1210/me.2007-0183  1
2007 Zhao X, Nothwehr S, Lara-Lemus R, Zhang BY, Peter H, Arvan P. Dominant-negative behavior of mammalian Vps35 in yeast requires a conserved PRLYL motif involved in retromer assembly. Traffic (Copenhagen, Denmark). 8: 1829-40. PMID 17916227 DOI: 10.1111/j.1600-0854.2007.00658.x  1
2007 Liu M, Hodish I, Rhodes CJ, Arvan P. Proinsulin maturation, misfolding, and proteotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 104: 15841-6. PMID 17898179 DOI: 10.1073/pnas.0702697104  1
2006 Forster ML, Sivick K, Park YN, Arvan P, Lencer WI, Tsai B. Protein disulfide isomerase-like proteins play opposing roles during retrotranslocation. The Journal of Cell Biology. 173: 853-9. PMID 16785320 DOI: 10.1083/jcb.200602046  1
2006 Hua QX, Liu M, Hu SQ, Jia W, Arvan P, Weiss MA. A conserved histidine in insulin is required for the foldability of human proinsulin: structure and function of an ALAB5 analog. The Journal of Biological Chemistry. 281: 24889-99. PMID 16728398 DOI: 10.1074/jbc.M602617200  1
2006 Lara-Lemus R, Liu M, Turner MD, Scherer P, Stenbeck G, Iyengar P, Arvan P. Lumenal protein sorting to the constitutive secretory pathway of a regulated secretory cell. Journal of Cell Science. 119: 1833-42. PMID 16608874 DOI: 10.1242/jcs.02905  1
2005 Liu M, Li Y, Cavener D, Arvan P. Proinsulin disulfide maturation and misfolding in the endoplasmic reticulum. The Journal of Biological Chemistry. 280: 13209-12. PMID 15705595 DOI: 10.1074/jbc.C400475200  1
2005 Ramos-Castañeda J, Park YN, Liu M, Hauser K, Rudolph H, Shull GE, Jonkman MF, Mori K, Ikeda S, Ogawa H, Arvan P. Deficiency of ATP2C1, a Golgi ion pump, induces secretory pathway defects in endoplasmic reticulum (ER)-associated degradation and sensitivity to ER stress. The Journal of Biological Chemistry. 280: 9467-73. PMID 15623514 DOI: 10.1074/jbc.M413243200  1
2004 Kuliawat R, Kalinina E, Bock J, Fricker L, McGraw TE, Kim SR, Zhong J, Scheller R, Arvan P. Syntaxin-6 SNARE involvement in secretory and endocytic pathways of cultured pancreatic beta-cells. Molecular Biology of the Cell. 15: 1690-701. PMID 14742717 DOI: 10.1091/mbc.E03-08-0554  1
2003 Liu M, Ramos-Castañeda J, Arvan P. Role of the connecting peptide in insulin biosynthesis. The Journal of Biological Chemistry. 278: 14798-805. PMID 12590147 DOI: 10.1074/jbc.M212070200  1
2003 Zhang BY, Liu M, Arvan P. Behavior in the eukaryotic secretory pathway of insulin-containing fusion proteins and single-chain insulins bearing various B-chain mutations. The Journal of Biological Chemistry. 278: 3687-93. PMID 12446709 DOI: 10.1074/jbc.M209474200  1
2002 Arvan P, Zhang BY, Feng L, Liu M, Kuliawat R. Lumenal protein multimerization in the distal secretory pathway/secretory granules. Current Opinion in Cell Biology. 14: 448-53. PMID 12383795 DOI: 10.1016/S0955-0674(02)00344-7  1
2001 Schlegel A, Arvan P, Lisanti MP. Caveolin-1 binding to endoplasmic reticulum membranes and entry into the regulated secretory pathway are regulated by serine phosphorylation. Protein sorting at the level of the endoplasmic reticulum. The Journal of Biological Chemistry. 276: 4398-408. PMID 11078729 DOI: 10.1074/jbc.M005448200  1
2000 Turner MD, Arvan P. Protein traffic from the secretory pathway to the endosomal system in pancreatic beta-cells. The Journal of Biological Chemistry. 275: 14025-30. PMID 10799475 DOI: 10.1074/jbc.275.19.14025  1
1998 Kim PS, Hossain SA, Park YN, Lee I, Yoo SE, Arvan P. A single amino acid change in the acetylcholinesterase-like domain of thyroglobulin causes congenital goiter with hypothyroidism in the cog/cog mouse: A model of human endoplasmic reticulum storage diseases Proceedings of the National Academy of Sciences of the United States of America. 95: 9909-9913. PMID 9707574 DOI: 10.1073/pnas.95.17.9909  1
1997 Huang XF, Compans RW, Chen S, Lamb RA, Arvan P. Polarized apical targeting directed by the signal/anchor region of simian virus 5 hemagglutinin-neuraminidase. The Journal of Biological Chemistry. 272: 27598-604. PMID 9346896 DOI: 10.1074/jbc.272.44.27598  1
1997 Arvan P, Kim PS, Kuliawat R, Prabakaran D, Muresan Z, Yoo SE, Hossain SA. Intracellular protein transport to the thyrocyte plasma membrane: Potential implications for thyroid physiology Thyroid. 7: 89-105. PMID 9086577 DOI: 10.1089/thy.1997.7.89  1
1996 Medelros-Neto G, Kim PS, Yoo SE, Vono J, Targovnik HM, Camargo R, Hossain SA, Arvan P. Congenital hypothyroid goiter with deficient thyroglobulin: Identification of an endoplasmic reticulum storage disease with induction of molecular chaperones Journal of Clinical Investigation. 98: 2838-2844. PMID 8981932 DOI: 10.1172/JCI119112  1
1995 Kuliawat R, Lisanti MP, Arvan P. Polarized distribution and delivery of plasma membrane proteins in thyroid follicular epithelial cells Journal of Biological Chemistry. 270: 2478-2482. PMID 7852309 DOI: 10.1074/jbc.270.6.2478  1
1987 Castle JD, Arvan P, Cameron R. Protein production and secretion in exocrine cells. Journal of Dental Research. 66: 633-7. PMID 3476628 DOI: 10.1177/00220345870660S105  1
1987 Castle JD, Cameron RS, Arvan P, von Zastrow M, Rudnick G. Similarities and differences among neuroendocrine, exocrine, and endocytic vesicles. Annals of the New York Academy of Sciences. 493: 448-60. PMID 3296913  1
1987 Arvan P, Castle JD. Phasic release of newly synthesized secretory proteins in the unstimulated rat exocrine pancreas. The Journal of Cell Biology. 104: 243-52. PMID 2433293  1
1986 Arvan P, Castle JD. Isolated secretion granules from parotid glands of chronically stimulated rats possess an alkaline internal pH and inward-directed H+ pump activity. The Journal of Cell Biology. 103: 1257-67. PMID 3021780  1
1985 Arvan P, Rudnick G, Castle JD. Relative lack of ATP-driven H+ translocase activity in isolated parotid secretory granules. The Journal of Biological Chemistry. 260: 14945-52. PMID 2866180  1
1984 Arvan P, Rudnick G, Castle JD. Osmotic properties and internal pH of isolated rat parotid secretory granules. The Journal of Biological Chemistry. 259: 13567-72. PMID 6490664  1
1983 Arvan P, Cameron RS, Castle JD. Secretory membranes of the rat parotid gland: preparation and comparative characterization. Methods in Enzymology. 98: 75-87. PMID 6669072  1
1982 Arvan P, Castle JD. Plasma membrane of the rat parotid gland: preparation and partial characterization of a fraction containing the secretory surface. The Journal of Cell Biology. 95: 8-19. PMID 6128347  1
1976 Miller C, Arvan P, Telford JN, Racker E. Ca++-induced fusion of proteoliposomes: dependence on transmembrane osmotic gradient. The Journal of Membrane Biology. 30: 271-82. PMID 188553 DOI: 10.1007/BF01869672  1
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