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Rick H. Cote, Ph.D. - Publications

Affiliations: 
1988-2008 Biochemistry University of New Hampshire, Durham, NH, United States 
 2008- Molecular, Cellular, and Biomedical Sciences University of New Hampshire, Durham, NH, United States 
Area:
Biochemistry, Neuroscience, Pharmacology
Website:
www.cotelab.org
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54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Irwin MJ, Wang X, Cote RH. Reconstitution of Membrane-associated Components of a G-protein Signaling Pathway on Membrane-coated Nanoparticles (Lipobeads). Bio-Protocol. 12: e4303. PMID 35127993 DOI: 10.21769/BioProtoc.4303  0.717
2021 Cote RH, Gupta R, Irwin MJ, Wang X. Photoreceptor Phosphodiesterase (PDE6): Structure, Regulatory Mechanisms, and Implications for Treatment of Retinal Diseases. Advances in Experimental Medicine and Biology. PMID 34170501 DOI: 10.1007/5584_2021_649  0.8
2021 Cote RH. Photoreceptor phosphodiesterase (PDE6): activation and inactivation mechanisms during visual transduction in rods and cones. Pflugers Archiv : European Journal of Physiology. PMID 33860373 DOI: 10.1007/s00424-021-02562-x  0.486
2020 Gupta R, Liu Y, Wang H, Nordyke CT, Puterbaugh RZ, Cui W, Varga K, Chu F, Ke H, Vashisth H, Cote RH. Structural Analysis of the Regulatory GAF Domains of cGMP Phosphodiesterase Elucidates the Allosteric Communication Pathway. Journal of Molecular Biology. PMID 32898583 DOI: 10.1016/J.Jmb.2020.08.026  0.785
2019 Irwin MJ, Gupta R, Gao XZ, Cahill KB, Chu F, Cote RH. The molecular architecture of photoreceptor phosphodiesterase 6 (PDE6) with activated G protein elucidates the mechanism of visual excitation. The Journal of Biological Chemistry. PMID 31690623 DOI: 10.1074/Jbc.Ra119.011002  0.832
2019 Chu F, Hogan D, Gupta R, Gao XZ, Nguyen HT, Cote RH. Allosteric Regulation of Rod Photoreceptor Phosphodiesterase 6 (PDE6) Elucidated by Chemical Cross-Linking and Quantitative Mass Spectrometry. Journal of Molecular Biology. PMID 31394113 DOI: 10.1016/J.Jmb.2019.07.035  0.822
2019 Wang X, Plachetzki DC, Cote RH. The N termini of the inhibitory γ-subunits of phosphodiesterase-6 (PDE6) from rod and cone photoreceptors differentially regulate transducin-mediated PDE6 activation. The Journal of Biological Chemistry. PMID 30962282 DOI: 10.1074/Jbc.Ra119.007520  0.739
2019 Schuster KD, Mohammadi M, Cahill KB, Matte SL, Maillet AD, Vashisth H, Cote RH. Pharmacological and molecular dynamics analyses of differences in inhibitor binding to human and nematode PDE4: Implications for management of parasitic nematodes. Plos One. 14: e0214554. PMID 30917179 DOI: 10.1371/Journal.Pone.0214554  0.792
2014 Zeng-Elmore X, Gao XZ, Pellarin R, Schneidman-Duhovny D, Zhang XJ, Kozacka KA, Tang Y, Sali A, Chalkley RJ, Cote RH, Chu F. Molecular architecture of photoreceptor phosphodiesterase elucidated by chemical cross-linking and integrative modeling. Journal of Molecular Biology. 426: 3713-28. PMID 25149264 DOI: 10.1016/J.Jmb.2014.07.033  0.804
2013 Schuster KD, Cahill KB, Morris K, Thomas WK, Cote RH. PDE inhibitors as potential pesticides targeting parasitic nematodes The Faseb Journal. 27. DOI: 10.1096/Fasebj.27.1_Supplement.1052.6  0.748
2012 Cahill KB, Quade JH, Carleton KL, Cote RH. Identification of amino acid residues responsible for the selectivity of tadalafil binding to two closely related phosphodiesterases, PDE5 and PDE6. The Journal of Biological Chemistry. 287: 41406-16. PMID 23033484 DOI: 10.1074/Jbc.M112.389189  0.828
2012 Zhang XJ, Gao XZ, Yao W, Cote RH. Functional mapping of interacting regions of the photoreceptor phosphodiesterase (PDE6) γ-subunit with PDE6 catalytic dimer, transducin, and regulator of G-protein signaling9-1 (RGS9-1). The Journal of Biological Chemistry. 287: 26312-20. PMID 22665478 DOI: 10.1074/Jbc.M112.377333  0.84
2012 Matte SL, Laue TM, Cote RH. Characterization of conformational changes and protein-protein interactions of rod photoreceptor phosphodiesterase (PDE6). The Journal of Biological Chemistry. 287: 20111-21. PMID 22514270 DOI: 10.1074/Jbc.M112.354647  0.832
2011 Zhang XJ, Cote RH. Phosphodiesterase 6H, cone-specific inhibitor: Basis Sequence: Mouse. The Afcs-Nature Molecule Pages. 2011. PMID 32377172 DOI: 10.1038/Mp.A001758.01  0.724
2011 Cahill KB, Cote RH. Phosphodiesterase 6C, cGMP-specific cone alpha'. The Afcs-Nature Molecule Pages. 2011. PMID 26504430 DOI: 10.1038/Mp.A001756.01  0.797
2011 Gitschier HJ, Cote RH. Phosphodiesterase 6D, cGMP-specific rod delta. The Afcs-Nature Molecule Pages. 2011. PMID 26504429 DOI: 10.1038/Mp.A001757.01  0.787
2010 Zhang XJ, Skiba NP, Cote RH. Structural requirements of the photoreceptor phosphodiesterase gamma-subunit for inhibition of rod PDE6 holoenzyme and for its activation by transducin. The Journal of Biological Chemistry. 285: 4455-63. PMID 19948718 DOI: 10.1074/Jbc.M109.057406  0.78
2009 Liu YT, Matte SL, Corbin JD, Francis SH, Cote RH. Probing the catalytic sites and activation mechanism of photoreceptor phosphodiesterase using radiolabeled phosphodiesterase inhibitors. The Journal of Biological Chemistry. 284: 31541-7. PMID 19758990 DOI: 10.1074/Jbc.M109.018606  0.834
2008 Zhang XJ, Cahill KB, Elfenbein A, Arshavsky VY, Cote RH. Direct allosteric regulation between the GAF domain and catalytic domain of photoreceptor phosphodiesterase PDE6. The Journal of Biological Chemistry. 283: 29699-705. PMID 18779324 DOI: 10.1074/Jbc.M803948200  0.81
2006 Pentia DC, Hosier S, Cote RH. The glutamic acid-rich protein-2 (GARP2) is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties. The Journal of Biological Chemistry. 281: 5500-5. PMID 16407240 DOI: 10.1074/Jbc.M507488200  0.817
2005 Zhang H, Hosier S, Terew JM, Zhang K, Cote RH, Baehr W. Assay and functional properties of PrBP(PDEdelta), a prenyl-binding protein interacting with multiple partners. Methods in Enzymology. 403: 42-56. PMID 16473576 DOI: 10.1016/S0076-6879(05)03005-3  0.801
2005 Zhang X, Feng Q, Cote RH. Efficacy and selectivity of phosphodiesterase-targeted drugs in inhibiting photoreceptor phosphodiesterase (PDE6) in retinal photoreceptors. Investigative Ophthalmology & Visual Science. 46: 3060-6. PMID 16123402 DOI: 10.1167/Iovs.05-0257  0.802
2005 Carleton KL, Spady TC, Cote RH. Rod and cone opsin families differ in spectral tuning domains but not signal transducing domains as judged by saturated evolutionary trace analysis. Journal of Molecular Evolution. 61: 75-89. PMID 15988624 DOI: 10.1007/S00239-004-0289-Z  0.709
2005 Cote RH. Cyclic guanosine 5'-monophosphate binding to regulatory GAF domains of photoreceptor phosphodiesterase. Methods in Molecular Biology (Clifton, N.J.). 307: 141-54. PMID 15988061 DOI: 10.1385/1-59259-839-0:141  0.753
2005 Pentia DC, Hosier S, Collupy RA, Valeriani BA, Cote RH. Purification of PDE6 isozymes from mammalian retina. Methods in Molecular Biology (Clifton, N.J.). 307: 125-40. PMID 15988060 DOI: 10.1385/1-59259-839-0:125  0.744
2005 Zhang X, Cote RH. cGMP signaling in vertebrate retinal photoreceptor cells. Frontiers in Bioscience : a Journal and Virtual Library. 10: 1191-204. PMID 15769618 DOI: 10.2741/1612  0.762
2005 Norton AW, Hosier S, Terew JM, Li N, Dhingra A, Vardi N, Baehr W, Cote RH. Evaluation of the 17-kDa prenyl-binding protein as a regulatory protein for phototransduction in retinal photoreceptors. The Journal of Biological Chemistry. 280: 1248-56. PMID 15504722 DOI: 10.1074/Jbc.M410475200  0.803
2004 Cote RH. Characteristics of photoreceptor PDE (PDE6): similarities and differences to PDE5. International Journal of Impotence Research. 16: S28-33. PMID 15224133 DOI: 10.1038/Sj.Ijir.3901212  0.766
2003 Corbin JD, Kotera J, Gopal VK, Cote RH, Francis SH. Regulation of Cyclic Nucleotide Levels by Sequestration Handbook of Cell Signaling. 2: 465-470. DOI: 10.1016/B978-012124546-7/50559-3  0.603
2003 Cote RH. Structure, Function, and Regulation of Photoreceptor Phosphodiesterase (PDE6) Handbook of Cell Signaling. 2: 453-457. DOI: 10.1016/B978-012124546-7/50557-X  0.629
2002 Paglia MJ, Mou H, Cote RH. Regulation of photoreceptor phosphodiesterase (PDE6) by phosphorylation of its inhibitory gamma subunit re-evaluated. The Journal of Biological Chemistry. 277: 5017-23. PMID 11741972 DOI: 10.1074/Jbc.M106328200  0.816
2001 Kameni Tcheudji JF, Lebeau L, Virmaux N, Maftei CG, Cote RH, Lugnier C, Schultz P. Molecular organization of bovine rod cGMP-phosphodiesterase 6. Journal of Molecular Biology. 310: 781-91. PMID 11453687 DOI: 10.1006/Jmbi.2001.4813  0.809
2001 Mou H, Cote RH. The catalytic and GAF domains of the rod cGMP phosphodiesterase (PDE6) heterodimer are regulated by distinct regions of its inhibitory gamma subunit. The Journal of Biological Chemistry. 276: 27527-34. PMID 11375400 DOI: 10.1074/Jbc.M103316200  0.806
2000 Norton AW, D'Amours MR, Grazio HJ, Hebert TL, Cote RH. Mechanism of transducin activation of frog rod photoreceptor phosphodiesterase. Allosteric interactiona between the inhibitory gamma subunit and the noncatalytic cGMP-binding sites. The Journal of Biological Chemistry. 275: 38611-9. PMID 10993884 DOI: 10.1074/Jbc.M004606200  0.82
2000 Cote RH. Kinetics and regulation of cGMP binding to noncatalytic binding sites on photoreceptor phosphodiesterase. Methods in Enzymology. 315: 646-72. PMID 10736732  0.701
1999 Mou H, Grazio HJ, Cook TA, Beavo JA, Cote RH. cGMP binding to noncatalytic sites on mammalian rod photoreceptor phosphodiesterase is regulated by binding of its gamma and delta subunits. The Journal of Biological Chemistry. 274: 18813-20. PMID 10373499 DOI: 10.1074/Jbc.274.26.18813  0.805
1999 D'Amours MR, Cote RH. Regulation of photoreceptor phosphodiesterase catalysis by its non-catalytic cGMP-binding sites. The Biochemical Journal. 340: 863-9. PMID 10359674 DOI: 10.1042/Bj3400863  0.831
1999 D'Amours MR, Granovsky AE, Artemyev NO, Cote RH. Potency and mechanism of action of E4021, a type 5 phosphodiesterase isozyme-selective inhibitor, on the photoreceptor phosphodiesterase depend on the state of activation of the enzyme. Molecular Pharmacology. 55: 508-14. PMID 10051534  0.818
1998 Artemyev NO, Arshavsky VY, Cote RH. Photoreceptor phosphodiesterase: interaction of inhibitory gamma subunit and cyclic GMP with specific binding sites on catalytic subunits. Methods (San Diego, Calif.). 14: 93-104. PMID 9500861 DOI: 10.1006/Meth.1997.0568  0.77
1998 Hebert MC, Schwede F, Jastorff B, Cote RH. Structural features of the noncatalytic cGMP binding sites of frog photoreceptor phosphodiesterase using cGMP analogs. The Journal of Biological Chemistry. 273: 5557-65. PMID 9488681 DOI: 10.1074/Jbc.273.10.5557  0.737
1994 Cote RH, Bownds MD, Arshavsky VY. cGMP binding sites on photoreceptor phosphodiesterase: role in feedback regulation of visual transduction. Proceedings of the National Academy of Sciences of the United States of America. 91: 4845-9. PMID 8197145 DOI: 10.1073/Pnas.91.11.4845  0.756
1994 Coccia VJ, Cote RH. Regulation of intracellular cyclic GMP concentration by light and calcium in electropermeabilized rod photoreceptors. The Journal of General Physiology. 103: 67-86. PMID 8169598 DOI: 10.1085/Jgp.103.1.67  0.764
1993 Cote RH, Brunnock MA. Intracellular cGMP concentration in rod photoreceptors is regulated by binding to high and moderate affinity cGMP binding sites. The Journal of Biological Chemistry. 268: 17190-8. PMID 8394335  0.722
1993 Forget RS, Martin JE, Cote RH. A centrifugal separation procedure detects moderate affinity cGMP binding sites in membrane-associated proteins and permeabilized cells. Analytical Biochemistry. 215: 159-61. PMID 8297009 DOI: 10.1006/Abio.1993.1570  0.81
1992 Lisman J, Erickson MA, Richard EA, Cote RH, Bacigalupo J, Johnson E, Kirkwood A. Mechanisms of amplification, deactivation, and noise reduction in invertebrate photoreceptors. Society of General Physiologists Series. 47: 175-99. PMID 1369761  0.671
1989 Robinson PR, Cote RH. Characterization of guanylate cyclase in squid photoreceptors. Visual Neuroscience. 3: 1-7. PMID 2577264 DOI: 10.1017/S0952523800012451  0.771
1989 Cote RH, Nicol GD, Burke SA, Bownds MD. Cyclic GMP levels and membrane current during onset, recovery, and light adaptation of the photoresponse of detached frog photoreceptors. The Journal of Biological Chemistry. 264: 15384-91. PMID 2549061  0.767
1986 Cote RH, Nicol GD, Burke SA, Bownds MD. Changes in cGMP concentration correlate with some, but not all, aspects of the light-regulated conductance of frog rod photoreceptors. The Journal of Biological Chemistry. 261: 12965-75. PMID 3020017  0.771
1986 Robinson PR, Radeke MJ, Cote RH, Bownds MD. cGMP influences guanine nucleotide binding to frog photoreceptor G-protein. The Journal of Biological Chemistry. 261: 313-8. PMID 3001052  0.712
1984 Cote RH, Biernbaum MS, Nicol GD, Bownds MD. Light-induced decreases in cGMP concentration precede changes in membrane permeability in frog rod photoreceptors. The Journal of Biological Chemistry. 259: 9635-41. PMID 6086642  0.776
1981 Cote RH, Anderson CF, Borisy GG. Formulation of the general rate equation for subunit flux at steady-state. Journal of Molecular Biology. 150: 599-602. PMID 7328647 DOI: 10.1016/0022-2836(81)90383-1  0.698
1981 Cote RH, Borisy GG. Head-to-tail polymerization of microtubules in vitro. Journal of Molecular Biology. 150: 577-99. PMID 7328646 DOI: 10.1016/0022-2836(81)90382-X  0.725
1977 Abe M, Brown C, Hendrickson WG, Boyd DH, Clifford P, Cote RH, Schaechter M. Release of Escherichia coli DNA from membrane complexes by single-strand endonucleases. Proceedings of the National Academy of Sciences of the United States of America. 74: 2756-60. PMID 331316 DOI: 10.1073/Pnas.74.7.2756  0.649
1974 Sonenshein AL, Cami B, Brevet J, Cote R. Isolation and characterization of rifampin resistant and streptolydigin resistant mutants of Bacillus subtilis with altered sporulation properties Journal of Bacteriology. 120: 253-265. PMID 4370705 DOI: 10.1128/Jb.120.1.253-265.1974  0.698
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