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Maarten Eduard Anton Reith - Publications

Affiliations: 
Illinois State University, Normal, IL, United States 
 New York University, New York, NY, United States 
Area:
Neuroscience Biology, Biochemistry
Website:
https://med.nyu.edu/faculty/maarten-reith

177 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Dutta AK, Santra S, Harutyunyan A, Das B, Michael Lisieski, Xu L, Antonio T, Reith MEA, Perrine SA. D-578, an orally active triple monoamine reuptake inhibitor, displays antidepressant and anti-PTSD effects in rats. European Journal of Pharmacology. 172632. PMID 31473161 DOI: 10.1016/j.ejphar.2019.172632  1
2019 Xu W, Reith MEA, Chen LL, Kortagere S. Biased signaling agonist of Dopamine D3 receptor induces receptor internalization independent of β-Arrestin recruitment. Pharmacological Research. PMID 30844536 DOI: 10.1016/j.phrs.2019.03.003  0.48
2019 Marshall CA, Brodnik ZD, Mortensen OV, Reith MEA, Shumsky JS, Waterhouse BD, España RA, Kortagere S. Selective activation of Dopamine D3 receptors and norepinephrine transporter blockade enhances sustained attention. Neuropharmacology. 148: 178-188. PMID 30633928 DOI: 10.1016/j.neuropharm.2019.01.003  0.48
2018 Elmabruk A, Das B, Yedlapudi D, Xu L, Antonio T, Reith MEA, Dutta AK. Design, Synthesis and Pharmacological Characterization of Carbazole Based Dopamine Agonists as Potential Symptomatic and Neuroprotective Therapeutic Agents for Parkinson's Disease. Acs Chemical Neuroscience. PMID 30301349 DOI: 10.1021/acschemneuro.8b00291  1
2018 Mikelman SR, Guptaroy B, Schmitt KC, Jones KT, Zhen J, Reith MEA, Gnegy ME. Tamoxifen Directly Interacts with the Dopamine Transporter. The Journal of Pharmacology and Experimental Therapeutics. PMID 30108161 DOI: 10.1124/jpet.118.248179  1
2017 Reith MEA, Jones KT, Zhen J, Topiol S. Latch and trigger role for R445 in DAT transport explains molecular basis of DTDS. Bioorganic & Medicinal Chemistry Letters. PMID 29258773 DOI: 10.1016/j.bmcl.2017.12.016  1
2017 Zhen J, Reith MEA. Functional properties of dopamine transporter oligomers after copper linking. Journal of Neurochemistry. PMID 29168892 DOI: 10.1111/jnc.14259  1
2017 Challasivakanaka S, Zhen J, Smith ME, Reith MEA, Foster JD, Vaughan RA. Dopamine Transporter Phosphorylation Site Threonine 53 is Stimulated by Amphetamines and Regulates Dopamine Transport, Efflux, and Cocaine Analog Binding. The Journal of Biological Chemistry. PMID 28939767 DOI: 10.1074/jbc.M117.787002  1
2017 Das B, Kandegedara A, Xu L, Antonio T, Stemmler T, Reith MEA, Dutta AK. A Novel Iron(II) Preferring Dopamine Agonist Chelator as Potential Symptomatic and Neuroprotective Therapeutic Agent for Parkinson's Disease. Acs Chemical Neuroscience. 8: 723-730. PMID 28106982 DOI: 10.1021/acschemneuro.6b00356  1
2017 Jones KT, Woods C, Zhen J, Antonio T, Carr KD, Reith ME. Effects of diet and insulin on dopamine transporter activity and expression in rat caudate-putamen, nucleus accumbens, and midbrain. Journal of Neurochemistry. 140: 728-740. PMID 27973691 DOI: 10.1111/jnc.13930  1
2017 Xu W, Wang X, Tocker AM, Huang P, Reith ME, Liu-Chen LY, Smith AB, Kortagere S. Functional Characterization of a Novel Series of Biased Signaling Dopamine D3 Receptor Agonists. Acs Chemical Neuroscience. 8: 486-500. PMID 27801563 DOI: 10.1021/acschemneuro.6b00221  0.48
2016 Luo D, Sharma H, Yedlapudi D, Antonio T, Reith MEA, Dutta AK. Novel multifunctional dopamine D2/D3 receptors agonists with potential neuroprotection and anti-alpha synuclein protein aggregation properties. Bioorganic & Medicinal Chemistry. 24: 5088-5102. PMID 27591013 DOI: 10.1016/j.bmc.2016.08.021  1
2016 Zhen J, Reith ME. Impact of disruption of secondary binding site S2 on dopamine transporter function. Journal of Neurochemistry. 138: 694-9. PMID 27315582 DOI: 10.1111/jnc.13704  1
2016 Zhen J, Antonio T, Jacob JC, Grandy DK, Reith MEA, Dutta AK, Selley DE. Efficacy of Hybrid Tetrahydrobenzo[d]thiazole Based Aryl Piperazines D-264 and D-301 at D₂ and D₃ Receptors. Neurochemical Research. 41: 328-339. PMID 26718829 DOI: 10.1007/s11064-015-1808-6  1
2015 Das B, Vedachalam S, Luo D, Antonio T, Reith ME, Dutta AK. Development of a Highly Potent D2/D3 Agonist and a Partial Agonist from Structure-Activity Relationship Study of N(6)-(2-(4-(1H-Indol-5-yl)piperazin-1-yl)ethyl)-N(6)-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine Analogues: Implication in the Treatment of Parkinson's Disease. Journal of Medicinal Chemistry. 58: 9179-95. PMID 26555041 DOI: 10.1021/acs.jmedchem.5b01031  1
2015 Stouffer MA, Woods CA, Patel JC, Lee CR, Witkovsky P, Bao L, Machold RP, Jones KT, de Vaca SC, Reith ME, Carr KD, Rice ME. Insulin enhances striatal dopamine release by activating cholinergic interneurons and thereby signals reward. Nature Communications. 6: 8543. PMID 26503322 DOI: 10.1038/ncomms9543  1
2015 Stödberg T, McTague A, Ruiz AJ, Hirata H, Zhen J, Long P, Farabella I, Meyer E, Kawahara A, Vassallo G, Stivaros SM, Bjursell MK, Stranneheim H, Tigerschiöld S, Persson B, ... ... Reith ME, et al. Mutations in SLC12A5 in epilepsy of infancy with migrating focal seizures. Nature Communications. 6: 8038. PMID 26333769 DOI: 10.1038/ncomms9038  1
2015 Zhen J, Antonio T, Ali S, Neve KA, Dutta AK, Reith ME. Use of radiolabeled antagonist assays for assessing agonism at D2 and D3 dopamine receptors: comparison with functional GTPγS assays. Journal of Neuroscience Methods. 248: 7-15. PMID 25840364 DOI: 10.1016/j.jneumeth.2015.03.028  1
2015 Zhen J, Antonio T, Cheng SY, Ali S, Jones KT, Reith ME. Dopamine transporter oligomerization: impact of combining protomers with differential cocaine analog binding affinities. Journal of Neurochemistry. 133: 167-73. PMID 25580950 DOI: 10.1111/jnc.13025  1
2015 Reith ME, Blough BE, Hong WC, Jones KT, Schmitt KC, Baumann MH, Partilla JS, Rothman RB, Katz JL. Behavioral, biological, and chemical perspectives on atypical agents targeting the dopamine transporter. Drug and Alcohol Dependence. 147: 1-19. PMID 25548026 DOI: 10.1016/j.drugalcdep.2014.12.005  1
2014 Dutta AK, Santra S, Sharma H, Voshavar C, Xu L, Mabrouk O, Antonio T, Reith ME. Pharmacological and behavioral characterization of D-473, an orally active triple reuptake inhibitor targeting dopamine, serotonin and norepinephrine transporters. Plos One. 9: e113420. PMID 25427177 DOI: 10.1371/journal.pone.0113420  1
2014 Ananthan S, Saini SK, Zhou G, Hobrath JV, Padmalayam I, Zhai L, Bostwick JR, Antonio T, Reith ME, McDowell S, Cho E, McAleer L, Taylor M, Luedtke RR. Design, synthesis, and structure-activity relationship studies of a series of [4-(4-carboxamidobutyl)]-1-arylpiperazines: insights into structural features contributing to dopamine D3 versus D2 receptor subtype selectivity. Journal of Medicinal Chemistry. 57: 7042-60. PMID 25126833 DOI: 10.1021/jm500801r  1
2014 Modi G, Voshavar C, Gogoi S, Shah M, Antonio T, Reith ME, Dutta AK. Multifunctional D2/D3 agonist D-520 with high in vivo efficacy: modulator of toxicity of alpha-synuclein aggregates. Acs Chemical Neuroscience. 5: 700-17. PMID 24960209 DOI: 10.1021/cn500084x  1
2014 Ng J, Zhen J, Meyer E, Erreger K, Li Y, Kakar N, Ahmad J, Thiele H, Kubisch C, Rider NL, Morton DH, Strauss KA, Puffenberger EG, D'Agnano D, Anikster Y, ... ... Reith ME, et al. Dopamine transporter deficiency syndrome: phenotypic spectrum from infancy to adulthood. Brain : a Journal of Neurology. 137: 1107-19. PMID 24613933 DOI: 10.1093/brain/awu022  1
2013 Antonio T, Childers SR, Rothman RB, Dersch CM, King C, Kuehne M, Bornmann WG, Eshleman AJ, Janowsky A, Simon ER, Reith ME, Alper K. Effect of Iboga alkaloids on µ-opioid receptor-coupled G protein activation. Plos One. 8: e77262. PMID 24204784 DOI: 10.1371/journal.pone.0077262  1
2013 Schmitt KC, Rothman RB, Reith ME. Nonclassical pharmacology of the dopamine transporter: atypical inhibitors, allosteric modulators, and partial substrates. The Journal of Pharmacology and Experimental Therapeutics. 346: 2-10. PMID 23568856 DOI: 10.1124/jpet.111.191056  1
2013 Johnson M, Antonio T, Reith ME, Dutta AK. Correction to Structure-Activity Relationship Study of N(6)-(2-(4-(1H-Indol-5-yl)piperazin-1-yl)ethyl)-N(6)-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine Analogues: Development of Highly Selective D3 Dopamine Receptor Agonists along with a Highly Potent D2/D3 Agonist and Their Pharmacological Characterization. Journal of Medicinal Chemistry. 56: 589-90. PMID 23289730 DOI: 10.1021/jm301634c  1
2012 Gogoi S, Biswas S, Modi G, Antonio T, Reith ME, Dutta AK. Novel bivalent ligands for D2/D3 dopamine receptors: Significant co-operative gain in D2 affinity and potency. Acs Medicinal Chemistry Letters. 3: 991-996. PMID 23275802 DOI: 10.1021/ml3002117  1
2012 Santra S, Gogoi S, Gopishetty B, Antonio T, Zhen J, Reith ME, Dutta AK. Structural exploration of (3S,6S)-6-benzhydryl-N-benzyltetrahydro-2H-pyran-3-amine analogues: identification of potent triple monoamine reuptake inhibitors as potential antidepressants. Chemmedchem. 7: 2093-100. PMID 23060293 DOI: 10.1002/cmdc.201200352  1
2012 Jones KT, Zhen J, Reith ME. Importance of cholesterol in dopamine transporter function. Journal of Neurochemistry. 123: 700-15. PMID 22957537 DOI: 10.1111/jnc.12007  1
2012 Reith ME, Ali S, Hashim A, Sheikh IS, Theddu N, Gaddiraju NV, Mehrotra S, Schmitt KC, Murray TF, Sershen H, Unterwald EM, Davis FA. Novel C-1 substituted cocaine analogs unlike cocaine or benztropine. The Journal of Pharmacology and Experimental Therapeutics. 343: 413-25. PMID 22895898 DOI: 10.1124/jpet.112.193771  1
2012 Johnson M, Antonio T, Reith ME, Dutta AK. Structure-activity relationship study of N⁶-(2-(4-(1H-Indol-5-yl)piperazin-1-yl)ethyl)-N⁶-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine analogues: development of highly selective D3 dopamine receptor agonists along with a highly potent D2/D3 agonist and their pharmacological characterization. Journal of Medicinal Chemistry. 55: 5826-40. PMID 22642365 DOI: 10.1021/jm300268s  1
2012 Alper K, Reith ME, Sershen H. Ibogaine and the inhibition of acetylcholinesterase. Journal of Ethnopharmacology. 139: 879-82. PMID 22200647 DOI: 10.1016/j.jep.2011.12.006  0.44
2012 Zhen J, Ali S, Dutta AK, Reith ME. Characterization of [³H]CFT binding to the norepinephrine transporter suggests that binding of CFT and nisoxetine is not mutually exclusive. Journal of Neuroscience Methods. 203: 19-27. PMID 21933682 DOI: 10.1016/j.jneumeth.2011.08.044  1
2011 Schmitt KC, Reith ME. The atypical stimulant and nootropic modafinil interacts with the dopamine transporter in a different manner than classical cocaine-like inhibitors. Plos One. 6: e25790. PMID 22043293 DOI: 10.1371/journal.pone.0025790  1
2011 Stouffer MA, Ali S, Reith ME, Patel JC, Sarti F, Carr KD, Rice ME. SKF-83566, a D1-dopamine receptor antagonist, inhibits the dopamine transporter. Journal of Neurochemistry. 118: 714-20. PMID 21689106 DOI: 10.1111/j.1471-4159.2011.07357.x  0.52
2011 Kurian MA, Li Y, Zhen J, Meyer E, Hai N, Christen HJ, Hoffmann GF, Jardine P, von Moers A, Mordekar SR, O'Callaghan F, Wassmer E, Wraige E, Dietrich C, Lewis T, ... ... Reith ME, et al. Clinical and molecular characterisation of hereditary dopamine transporter deficiency syndrome: an observational cohort and experimental study. The Lancet. Neurology. 10: 54-62. PMID 21112253 DOI: 10.1016/S1474-4422(10)70269-6  1
2011 Kortagere S, Cheng SY, Antonio T, Zhen J, Reith ME, Dutta AK. Interaction of novel hybrid compounds with the D3 dopamine receptor: Site-directed mutagenesis and homology modeling studies. Biochemical Pharmacology. 81: 157-63. PMID 20833147 DOI: 10.1016/j.bcp.2010.08.026  1
2010 Batman AM, Dutta AK, Reith ME, Beardsley PM. The selective dopamine uptake inhibitor, D-84, suppresses cocaine self-administration, but does not occasion cocaine-like levels of generalization. European Journal of Pharmacology. 648: 127-32. PMID 20840845 DOI: 10.1016/j.ejphar.2010.08.051  1
2010 Nyola A, Karpowich NK, Zhen J, Marden J, Reith ME, Wang DN. Substrate and drug binding sites in LeuT. Current Opinion in Structural Biology. 20: 415-22. PMID 20739005 DOI: 10.1016/j.sbi.2010.05.007  1
2010 Li Y, Cheng SY, Chen N, Reith ME. Interrelation of dopamine transporter oligomerization and surface presence as studied with mutant transporter proteins and amphetamine. Journal of Neurochemistry. 114: 873-85. PMID 20492355 DOI: 10.1111/j.1471-4159.2010.06818.x  1
2010 Schmitt KC, Reith ME. Regulation of the dopamine transporter: aspects relevant to psychostimulant drugs of abuse. Annals of the New York Academy of Sciences. 1187: 316-40. PMID 20201860 DOI: 10.1111/j.1749-6632.2009.05148.x  1
2010 Ghosh B, Antonio T, Reith ME, Dutta AK. Discovery of 4-(4-(2-((5-Hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)(propyl)amino)ethyl)piperazin-1-yl)quinolin-8-ol and its analogues as highly potent dopamine D2/D3 agonists and as iron chelator: in vivo activity indicates potential application in symptomatic and neuroprotective therapy for Parkinson's disease. Journal of Medicinal Chemistry. 53: 2114-25. PMID 20146482 DOI: 10.1021/jm901618d  1
2010 Zhen J, Antonio T, Dutta AK, Reith ME. Concentration of receptor and ligand revisited in a modified receptor binding protocol for high-affinity radioligands: [3H]Spiperone binding to D2 and D3 dopamine receptors. Journal of Neuroscience Methods. 188: 32-8. PMID 20122961 DOI: 10.1016/j.jneumeth.2010.01.031  1
2010 Schmitt KC, Mamidyala S, Biswas S, Dutta AK, Reith ME. Bivalent phenethylamines as novel dopamine transporter inhibitors: evidence for multiple substrate-binding sites in a single transporter. Journal of Neurochemistry. 112: 1605-18. PMID 20067583 DOI: 10.1111/j.1471-4159.2010.06583.x  1
2010 Ghosh B, Antonio T, Zhen J, Kharkar P, Reith ME, Dutta AK. Development of (S)-N6-(2-(4-(isoquinolin-1-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]-thiazole-2,6-diamine and its analogue as a D3 receptor preferring agonist: potent in vivo activity in Parkinson's disease animal models. Journal of Medicinal Chemistry. 53: 1023-37. PMID 20038106 DOI: 10.1021/jm901184n  1
2009 Liang YJ, Zhen J, Chen N, Reith ME. Interaction of catechol and non-catechol substrates with externally or internally facing dopamine transporters. Journal of Neurochemistry. 109: 981-94. PMID 19519772 DOI: 10.1111/j.1471-4159.2009.06034.x  1
2009 Kurian MA, Zhen J, Cheng SY, Li Y, Mordekar SR, Jardine P, Morgan NV, Meyer E, Tee L, Pasha S, Wassmer E, Heales SJ, Gissen P, Reith ME, Maher ER. Homozygous loss-of-function mutations in the gene encoding the dopamine transporter are associated with infantile parkinsonism-dystonia. The Journal of Clinical Investigation. 119: 1595-603. PMID 19478460 DOI: 10.1172/JCI39060  1
2009 Kharkar PS, Batman AM, Zhen J, Beardsley PM, Reith ME, Dutta AK. Synthesis and biological characterization of (3R,4R)-4-(2-(benzhydryloxy)ethyl)-1-((R)-2-hydroxy-2-phenylethyl)-piperidin-3-ol and its stereoisomers for activity toward monoamine transporters. Chemmedchem. 4: 1075-85. PMID 19449323 DOI: 10.1002/cmdc.200900085  1
2009 Zhou Z, Zhen J, Karpowich NK, Law CJ, Reith ME, Wang DN. Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures. Nature Structural & Molecular Biology. 16: 652-7. PMID 19430461 DOI: 10.1038/nsmb.1602  1
2009 Brown DA, Mishra M, Zhang S, Biswas S, Parrington I, Antonio T, Reith ME, Dutta AK. Investigation of various N-heterocyclic substituted piperazine versions of 5/7-{[2-(4-aryl-piperazin-1-yl)-ethyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-2-ol: effect on affinity and selectivity for dopamine D3 receptor. Bioorganic & Medicinal Chemistry. 17: 3923-33. PMID 19427222 DOI: 10.1016/j.bmc.2009.04.031  1
2008 Brown DA, Kharkar PS, Parrington I, Reith ME, Dutta AK. Structurally constrained hybrid derivatives containing octahydrobenzo[g or f]quinoline moieties for dopamine D2 and D3 receptors: binding characterization at D2/D3 receptors and elucidation of a pharmacophore model. Journal of Medicinal Chemistry. 51: 7806-19. PMID 19053758 DOI: 10.1021/jm8008629  1
2008 Schmitt KC, Zhen J, Kharkar P, Mishra M, Chen N, Dutta AK, Reith ME. Interaction of cocaine-, benztropine-, and GBR12909-like compounds with wild-type and mutant human dopamine transporters: molecular features that differentially determine antagonist-binding properties. Journal of Neurochemistry. 107: 928-40. PMID 18786172 DOI: 10.1111/j.1471-4159.2008.05667.x  1
2008 Dutta AK, Ghosh B, Biswas S, Reith ME. D-161, a novel pyran-based triple monoamine transporter blocker: behavioral pharmacological evidence for antidepressant-like action. European Journal of Pharmacology. 589: 73-9. PMID 18561912 DOI: 10.1016/j.ejphar.2008.05.008  1
2008 Biswas S, Hazeldine S, Ghosh B, Parrington I, Kuzhikandathil E, Reith ME, Dutta AK. Bioisosteric heterocyclic versions of 7-{[2-(4-phenyl-piperazin-1-yl)ethyl]propylamino}-5,6,7,8-tetrahydronaphthalen-2-ol: identification of highly potent and selective agonists for dopamine D3 receptor with potent in vivo activity. Journal of Medicinal Chemistry. 51: 3005-19. PMID 18410082 DOI: 10.1021/jm701524h  1
2008 Mishra M, Kolhatkar R, Zhen J, Parrington I, Reith ME, Dutta AK. Further structural optimization of cis-(6-benzhydryl-piperidin-3-yl)-benzylamine and 1,4-diazabicyclo[3.3.1]nonane derivatives by introducing an exocyclic hydroxyl group: interaction with dopamine, serotonin, and norepinephrine transporters. Bioorganic & Medicinal Chemistry. 16: 2769-78. PMID 18249549 DOI: 10.1016/j.bmc.2008.01.009  1
2008 Chen N, Reith ME. Substrates dissociate dopamine transporter oligomers. Journal of Neurochemistry. 105: 910-20. PMID 18088380 DOI: 10.1111/j.1471-4159.2007.05195.x  1
2008 Biswas S, Zhang S, Fernandez F, Ghosh B, Zhen J, Kuzhikandathil E, Reith ME, Dutta AK. Further structure-activity relationships study of hybrid 7-{[2-(4-phenylpiperazin-1-yl)ethyl]propylamino}-5,6,7,8-tetrahydronaphthalen-2-ol analogues: identification of a high-affinity D3-preferring agonist with potent in vivo activity with long duration of action. Journal of Medicinal Chemistry. 51: 101-17. PMID 18072730 DOI: 10.1021/jm070860r  1
2008 Kharkar PS, Reith ME, Dutta AK. Three-dimensional quantitative structure-activity relationship (3D QSAR) and pharmacophore elucidation of tetrahydropyran derivatives as serotonin and norepinephrine transporter inhibitors. Journal of Computer-Aided Molecular Design. 22: 1-17. PMID 18060532 DOI: 10.1007/s10822-007-9146-7  1
2007 Zhou Z, Zhen J, Karpowich NK, Goetz RM, Law CJ, Reith ME, Wang DN. LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake. Science (New York, N.Y.). 317: 1390-3. PMID 17690258 DOI: 10.1126/science.1147614  1
2007 Chen N, Reith ME. Substrates and inhibitors display different sensitivity to expression level of the dopamine transporter in heterologously expressing cells. Journal of Neurochemistry. 101: 377-88. PMID 17250655 DOI: 10.1111/j.1471-4159.2006.04384.x  1
2006 Zhang S, Fernandez F, Hazeldine S, Deschamps J, Zhen J, Reith ME, Dutta AK. Further structural exploration of trisubstituted asymmetric pyran derivatives (2S,4R,5R)-2-benzhydryl-5-benzylamino-tetrahydropyran-4-ol and their corresponding disubstituted (3S,6S) pyran derivatives: a proposed pharmacophore model for high-affinity interaction with the dopamine, serotonin, and norepinephrine transporters. Journal of Medicinal Chemistry. 49: 4239-47. PMID 16821783 DOI: 10.1021/jm0601699  1
2006 Reith ME, Zhen J, Chen N. The importance of company: Na+ and Cl- influence substrate interaction with SLC6 transporters and other proteins. Handbook of Experimental Pharmacology. 75-93. PMID 16722231 DOI: 10.1007/3-540-29784-7-4  0.96
2006 Zhen J, Reith ME, Carr KD. Chronic food restriction and dopamine transporter function in rat striatum. Brain Research. 1082: 98-101. PMID 16516172 DOI: 10.1016/j.brainres.2006.01.094  1
2006 Zhang S, Zhen J, Reith ME, Dutta AK. Design, synthesis, and preliminary SAR study of 3- and 6-side-chain-extended tetrahydro-pyran analogues of cis- and trans-(6-benzhydryl-tetrahydropyran-3-yl)-benzylamine. Bioorganic & Medicinal Chemistry. 14: 3953-66. PMID 16481172 DOI: 10.1016/j.bmc.2006.01.051  1
2005 Zhen J, Chen N, Reith ME. Differences in interactions with the dopamine transporter as revealed by diminishment of Na(+) gradient and membrane potential: dopamine versus other substrates. Neuropharmacology. 49: 769-79. PMID 16122767 DOI: 10.1016/j.neuropharm.2005.07.002  1
2005 Zhang S, Zhen J, Reith ME, Dutta AK. Discovery of novel trisubstituted asymmetric derivatives of (2S,4R,5R)-2-benzhydryl-5-benzylaminotetrahydropyran-4-ol, exhibiting high affinity for serotonin and norepinephrine transporters in a stereospecific manner. Journal of Medicinal Chemistry. 48: 4962-71. PMID 16033275 DOI: 10.1021/jm049021k  1
2005 Reith ME, Wang LC, Dutta AK. Pharmacological profile of radioligand binding to the norepinephrine transporter: instances of poor indication of functional activity. Journal of Neuroscience Methods. 143: 87-94. PMID 15763140 DOI: 10.1016/j.jneumeth.2004.09.015  1
2004 Zhen J, Maiti S, Chen N, Dutta AK, Reith ME. Interaction between a hydroxypiperidine analogue of 4-(2-benzhydryloxy-ethyl)-1-(4-fluorobenzyl)piperidine and Aspartate 68 in the human dopamine transporter. European Journal of Pharmacology. 506: 17-26. PMID 15588620 DOI: 10.1016/j.ejphar.2004.10.028  1
2004 Zhang S, Zhen J, Reith ME, Dutta AK. Structural requirements for 2,4- and 3,6-disubstituted pyran biomimetics of cis-(6-benzhydryl-piperidin-3-yl)-benzylamine compounds to interact with monoamine transporters. Bioorganic & Medicinal Chemistry. 12: 6301-15. PMID 15519172 DOI: 10.1016/j.bmc.2004.07.069  1
2004 Kolhatkar R, Cook CD, Ghorai SK, Deschamps J, Beardsley PM, Reith ME, Dutta AK. Further structurally constrained analogues of cis-(6-benzhydrylpiperidin-3-yl)benzylamine with elucidation of bioactive conformation: discovery of 1,4-diazabicyclo[3.3.1]nonane derivatives and evaluation of their biological properties for the monoamine transporters. Journal of Medicinal Chemistry. 47: 5101-13. PMID 15456254 DOI: 10.1021/jm049796t  1
2004 Dutta AK, Venkataraman SK, Fei XS, Kolhatkar R, Zhang S, Reith ME. Synthesis and biological characterization of novel hybrid 7-[[2-(4-phenyl-piperazin-1-yl)-ethyl]-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol and their heterocyclic bioisosteric analogues for dopamine D2 and D3 receptors. Bioorganic & Medicinal Chemistry. 12: 4361-73. PMID 15265488 DOI: 10.1016/j.bmc.2004.06.019  1
2004 Chen N, Zhen J, Reith ME. Mutation of Trp84 and Asp313 of the dopamine transporter reveals similar mode of binding interaction for GBR12909 and benztropine as opposed to cocaine. Journal of Neurochemistry. 89: 853-64. PMID 15140185 DOI: 10.1111/j.1471-4159.2004.02386.x  1
2004 Chen N, Reith ME. Interaction between dopamine and its transporter: role of intracellular sodium ions and membrane potential. Journal of Neurochemistry. 89: 750-65. PMID 15086531 DOI: 10.1111/j.1471-4159.2004.02409.x  1
2004 Li LB, Chen N, Ramamoorthy S, Chi L, Cui XN, Wang LC, Reith ME. The role of N-glycosylation in function and surface trafficking of the human dopamine transporter. The Journal of Biological Chemistry. 279: 21012-20. PMID 15024013 DOI: 10.1074/jbc.M311972200  1
2004 Appell M, Berfield JL, Wang LC, Dunn WJ, Chen N, Reith ME. Structure-activity relationships for substrate recognition by the human dopamine transporter. Biochemical Pharmacology. 67: 293-302. PMID 14698042  1
2004 Chen N, Rickey J, Berfield JL, Reith ME. Aspartate 345 of the dopamine transporter is critical for conformational changes in substrate translocation and cocaine binding. The Journal of Biological Chemistry. 279: 5508-19. PMID 14660644 DOI: 10.1074/jbc.M306294200  1
2004 Chen NH, Reith ME, Quick MW. Synaptic uptake and beyond: the sodium- and chloride-dependent neurotransmitter transporter family SLC6. Pflugers Archiv : European Journal of Physiology. 447: 519-31. PMID 12719981 DOI: 10.1007/s00424-003-1064-5  0.72
2003 Wang LC, Cui XN, Chen N, Reith ME. Binding of cocaine-like radioligands to the dopamine transporter at 37 degrees C: effect of Na+ and substrates. Journal of Neuroscience Methods. 131: 27-33. PMID 14659820  1
2003 Chen N, Reith ME. Na+ and the substrate permeation pathway in dopamine transporters. European Journal of Pharmacology. 479: 213-21. PMID 14612151  1
2003 Dutta AK, Zhang S, Kolhatkar R, Reith ME. Dopamine transporter as target for drug development of cocaine dependence medications. European Journal of Pharmacology. 479: 93-106. PMID 14612141  1
2003 Chen N, Appell M, Berfield JL, Reith ME. Inhibition by arachidonic acid and other fatty acids of dopamine uptake at the human dopamine transporter. European Journal of Pharmacology. 478: 89-95. PMID 14575792  1
2003 Chi L, Reith ME. Substrate-induced trafficking of the dopamine transporter in heterologously expressing cells and in rat striatal synaptosomal preparations. The Journal of Pharmacology and Experimental Therapeutics. 307: 729-36. PMID 12975490 DOI: 10.1124/jpet.103.055095  0.4
2003 Chen N, Rickey J, Reith ME. Na+ stimulates binding of dopamine to the dopamine transporter in cells but not in cell-free preparations. Journal of Neurochemistry. 86: 678-86. PMID 12859681  1
2003 Kolhatkar RB, Ghorai SK, George C, Reith ME, Dutta AK. Interaction of cis-(6-benzhydrylpiperidin-3-yl)benzylamine analogues with monoamine transporters: structure-activity relationship study of structurally constrained 3,6-disubstituted piperidine analogues of (2,2-diphenylethyl)-[1-(4-fluorobenzyl)piperidin-4-ylmethyl]amine. Journal of Medicinal Chemistry. 46: 2205-15. PMID 12747792 DOI: 10.1021/jm020561w  1
2003 Ghorai SK, Cook C, Davis M, Venkataraman SK, George C, Beardsley PM, Reith ME, Dutta AK. High affinity hydroxypiperidine analogues of 4-(2-benzhydryloxyethyl)-1-(4-fluorobenzyl)piperidine for the dopamine transporter: stereospecific interactions in vitro and in vivo. Journal of Medicinal Chemistry. 46: 1220-8. PMID 12646032 DOI: 10.1021/jm020275k  1
2002 Wu Q, Reith ME, Walker QD, Kuhn CM, Carroll FI, Garris PA. Concurrent autoreceptor-mediated control of dopamine release and uptake during neurotransmission: an in vivo voltammetric study. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 6272-81. PMID 12122086  0.56
2002 Chen N, Sun L, Reith ME. Cationic interactions at the human dopamine transporter reveal binding conformations for dopamine distinguishable from those for the cocaine analog 2 alpha-carbomethoxy-3 alpha-(4-fluorophenyl)tropane. Journal of Neurochemistry. 81: 1383-93. PMID 12068085  1
2002 Appell M, Dunn WJ, Reith ME, Miller L, Flippen-Anderson JL. An analysis of the binding of cocaine analogues to the monoamine transporters using tensor decomposition 3-d QSAR. Bioorganic & Medicinal Chemistry. 10: 1197-206. PMID 11886784  0.4
2002 Dutta AK, Fei XS, Reith ME. A novel series of hybrid compounds derived by combining 2-aminotetralin and piperazine fragments: binding activity at D2 and D3 receptors. Bioorganic & Medicinal Chemistry Letters. 12: 619-22. PMID 11844685  1
2002 Dutta AK, Davis MC, Fei XS, Beardsley PM, Cook CD, Reith ME. Expansion of structure-activity studies of piperidine analogues of 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine (GBR 12935) compounds by altering substitutions in the N-benzyl moiety and behavioral pharmacology of selected molecules. Journal of Medicinal Chemistry. 45: 654-62. PMID 11806716  1
2001 Wu Q, Reith ME, Wightman RM, Kawagoe KT, Garris PA. Determination of release and uptake parameters from electrically evoked dopamine dynamics measured by real-time voltammetry. Journal of Neuroscience Methods. 112: 119-33. PMID 11716947 DOI: 10.1016/S0165-0270(01)00459-9  0.96
2001 Wu Q, Reith ME, Kuhar MJ, Carroll FI, Garris PA. Preferential increases in nucleus accumbens dopamine after systemic cocaine administration are caused by unique characteristics of dopamine neurotransmission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 6338-47. PMID 11487657  0.96
2001 Reith ME, Berfield JL, Wang LC, Ferrer JV, Javitch JA. The uptake inhibitors cocaine and benztropine differentially alter the conformation of the human dopamine transporter. The Journal of Biological Chemistry. 276: 29012-8. PMID 11395483 DOI: 10.1074/jbc.M011785200  0.96
2001 Chen N, Vaughan RA, Reith ME. The role of conserved tryptophan and acidic residues in the human dopamine transporter as characterized by site-directed mutagenesis. Journal of Neurochemistry. 77: 1116-27. PMID 11359877  1
2000 Chen N, Reith MEA. Structure and function of the dopamine transporter European Journal of Pharmacology. 405: 329-339. PMID 11033338 DOI: 10.1016/S0014-2999(00)00563-X  0.96
2000 Wang LC, Berfield JL, Kuhar MJ, Carroll FI, Reith ME. RTI-76, an isothiocyanate derivative of a phenyltropane cocaine analog, as a tool for irreversibly inactivating dopamine transporter function in vitro. Naunyn-Schmiedeberg's Archives of Pharmacology. 362: 238-47. PMID 10997726 DOI: 10.1007/s002100000289  0.96
2000 Yan Q, Reith ME, Yan S. Enhanced accumbal dopamine release following 5-HT(2A) receptor stimulation in rats pretreated with intermittent cocaine. Brain Research. 863: 254-8. PMID 10773215  0.36
2000 Li LB, Reith ME. Interaction of Na+, K+, and Cl- with the binding of amphetamine, octopamine, and tyramine to the human dopamine transporter. Journal of Neurochemistry. 74: 1538-52. PMID 10737611 DOI: 10.1046/j.1471-4159.2000.0741538.x  0.96
1999 Li LB, Reith ME. Modeling of the interaction of Na+ and K+ with the binding of dopamine and [3H]WIN 35,428 to the human dopamine transporter. Journal of Neurochemistry. 72: 1095-109. PMID 10037481 DOI: 10.1046/j.1471-4159.1999.0721095.x  0.96
1999 Berfield JL, Wang LC, Reith ME. Which form of dopamine is the substrate for the human dopamine transporter: the cationic or the uncharged species? The Journal of Biological Chemistry. 274: 4876-82. PMID 9988729  0.4
1998 Li MY, Reith ME. Continuous cocaine treatment and monoamine transmission measured by microdialysis in the rat ventral tegmental area. Addiction Biology. 3: 447-51. PMID 26735119 DOI: 10.1080/13556219871985  0.96
1998 Yan QS, Reith ME, Yan SG, Jobe PC. Effect of systemic ethanol on basal and stimulated glutamate releases in the nucleus accumbens of freely moving Sprague-Dawley rats: a microdialysis study. Neuroscience Letters. 258: 29-32. PMID 9876044 DOI: 10.1016/S0304-3940(98)00840-4  0.96
1998 Reith ME, Xu C, Carroll FI, Chen NH. Inhibition of [3H]dopamine translocation and [3H]cocaine analog binding: a potential screening device for cocaine antagonists. Methods in Enzymology. 296: 248-59. PMID 9779453  0.72
1998 Dailey JW, Reith ME, Steidley KR, Milbrandt JC, Jobe PC. Carbamazepine-induced release of serotonin from rat hippocampus in vitro. Epilepsia. 39: 1054-63. PMID 9776325 DOI: 10.1111/j.1528-1157.1998.tb01290.x  0.96
1997 Li MY, Reith MEA. Effect of quinine on autoreceptor-regulated serotonin release in the rat hippocampus European Journal of Pharmacology. 340: 145-151. PMID 9537808 DOI: 10.1016/S0014-2999(97)01421-0  0.96
1997 Reith ME, Li MY, Yan QS. Extracellular dopamine, norepinephrine, and serotonin in the ventral tegmental area and nucleus accumbens of freely moving rats during intracerebral dialysis following systemic administration of cocaine and other uptake blockers. Psychopharmacology. 134: 309-17. PMID 9438681  0.68
1997 Yan QS, Reith ME, Jobe PC, Dailey JW. Dizocilpine (MK-801) increases not only dopamine but also serotonin and norepinephrine transmissions in the nucleus accumbens as measured by microdialysis in freely moving rats. Brain Research. 765: 149-58. PMID 9310406 DOI: 10.1016/S0006-8993(97)00568-4  0.96
1997 Wu Q, Coffey LL, Reith MEA. Cations affect [3H] mazindol and [3H] WIN 35,428 binding to the human dopamine transporter in a similar fashion Journal of Neurochemistry. 69: 1106-1118. PMID 9282933  0.96
1997 Xu C, Reith MEA. WIN 35,428 and mazindol are mutually exclusive in binding to the cloned human dopamine transporter Journal of Pharmacology and Experimental Therapeutics. 282: 920-927. PMID 9262359  0.96
1997 Dailey JW, Reith ME, Yan QS, Li MY, Jobe PC. Carbamazepine increases extracellular serotonin concentration: lack of antagonism by tetrodotoxin or zero Ca2+. European Journal of Pharmacology. 328: 153-62. PMID 9218697 DOI: 10.1016/S0014-2999(97)83041-5  0.96
1997 Dailey JW, Reith ME, Yan QS, Li MY, Jobe PC. Anticonvulsant doses of carbamazepine increase hippocampal extracellular serotonin in genetically epilepsy-prone rats: dose response relationships. Neuroscience Letters. 227: 13-6. PMID 9178847 DOI: 10.1016/S0304-3940(97)00288-7  0.96
1997 Reith ME, Xu C, Chen NH. Pharmacology and regulation of the neuronal dopamine transporter. European Journal of Pharmacology. 324: 1-10. PMID 9137907  0.72
1997 Zhang L, Coffey LL, Reith MEA. Regulation of the functional activity of the human dopamine transporter by protein kinase C Biochemical Pharmacology. 53: 677-688. PMID 9113087 DOI: 10.1016/S0006-2952(96)00898-2  0.96
1997 Xu C, Coffey LL, Reith MEA. Binding domains for blockers and substrates on the dopamine transporter in rat striatal membranes studied by protection against N-ethylmaleimide-induced reduction of [3H]WIN 35,428 binding Naunyn-Schmiedeberg's Archives of Pharmacology. 355: 64-73. PMID 9007844 DOI: 10.1007/PL00004919  0.96
1996 Zhang L, Reith MEA. Regulation of the functional activity of the human dopamine transporter by the arachidonic acid pathway European Journal of Pharmacology. 315: 345-354. PMID 8982675 DOI: 10.1016/S0014-2999(96)00646-2  0.96
1996 Reith MEA, Xu C, Coffey LL. Binding domains for blockers and substrates on the cloned human dopamine transporter studied by protection against N-ethylmaleimide-induced reduction of 2β-carbomethoxy-3β-(4-fluorophenyl)[3H]tropane ([3H]WIN 35,428) binding Biochemical Pharmacology. 52: 1435-1446. PMID 8937455 DOI: 10.1016/S0006-2952(96)00508-4  0.96
1996 Reith MEA, Xu C, Zhang L, Coffey LL. Translocation of dopamine and binding of WIN 35,428 measured under identical conditions in cells expressing the cloned human dopamine transporter Naunyn-Schmiedeberg's Archives of Pharmacology. 354: 295-304. PMID 8878059  0.96
1996 Chen SY, Burger RL, Reith MEA. Extracellular dopamine in the rat ventral tegmental area and nucleus accumbens following ventral tegmental infusion of cocaine Brain Research. 729: 294-296. PMID 8877004 DOI: 10.1016/S0006-8993(96)00671-3  0.96
1996 Xu C, Reith MEA. Modeling of the pH dependence of the binding of WIN 35,428 to the dopamine transporter in rat striatal membranes: Is the bioactive form positively charged or neutral? Journal of Pharmacology and Experimental Therapeutics. 278: 1340-1348. PMID 8819521  0.96
1996 Yan QS, Reith ME, Jobe PC, Dailey JW. Focal ethanol elevates extracellular dopamine and serotonin concentrations in the rat ventral tegmental area. European Journal of Pharmacology. 301: 49-57. PMID 8773446 DOI: 10.1016/0014-2999(96)00018-0  0.96
1996 Coffey LL, Reith ME, Chen NH, Mishra PK, Jobe PC. Amygdala kindling of forebrain seizures and the occurrence of brainstem seizures in genetically epilepsy-prone rats. Epilepsia. 37: 188-97. PMID 8635430 DOI: 10.1111/j.1528-1157.1996.tb00011.x  0.96
1996 Li MY, Yan QS, Coffey LL, Reith MEA. Extracellular dopamine, norepinephrine, and serotonin in the nucleus accumbens of freely moving rats during intracerebral dialysis with cocaine and other monoamine uptake blockers Journal of Neurochemistry. 66: 559-568. PMID 8592125  0.96
1995 Chen NH, Reith MEA. Monoamine interactions measured by microdialysis in the ventral tegmental area of rats treated systemically with (±)-8-hydroxy-2-(di-n-propylamino) tetralin Journal of Neurochemistry. 64: 1585-1597. PMID 7891086  0.96
1995 Xu C, Coffey LL, Reith MEA. Translocation of dopamine and binding of 2β-carbomethoxy-3 β-(4-fluorophenyl) tropane (WIN 35,428) measured under identical conditions in rat striatal synaptosomal preparations. Inhibition by various blockers Biochemical Pharmacology. 49: 339-350. PMID 7857321 DOI: 10.1016/0006-2952(94)00485-5  0.96
1994 Reith MEA, Coffey LL. [3H]WIN 35,428 binding to the dopamine uptake carrier. II. Effect of membrane fractionation procedure and freezing Journal of Neuroscience Methods. 51: 31-38. PMID 8189748 DOI: 10.1016/0165-0270(94)90023-X  0.96
1994 Coffey LL, Reith MEA. [3H]WIN 35,428 binding to the dopamine uptake carrier. I. Effect of tonicity and buffer composition Journal of Neuroscience Methods. 51: 23-30. PMID 8189747 DOI: 10.1016/0165-0270(94)90022-1  0.96
1994 Reith MEA, Coffey LL, Xu C, Chen NH. GBR 12909 and 12935 block dopamine uptake into brain synaptic vesicles as well as nerve endings European Journal of Pharmacology. 253: 175-178. PMID 8013544 DOI: 10.1016/0014-2999(94)90774-9  0.96
1994 Chen NH, Reith MEA. Autoregulation and monoamine interactions in the ventral tegmental area in the absence and presence of cocaine: A microdialysis study in freely moving rats Journal of Pharmacology and Experimental Therapeutics. 271: 1597-1610. PMID 7996474  0.96
1994 Reith MEA, Coffey LL. Structure-activity relationships for cocaine congeners in inhibiting dopamine uptake into rat brain synaptic vesicles and bovine chromaffin granule ghosts Journal of Pharmacology and Experimental Therapeutics. 271: 1444-1452. PMID 7996457  0.96
1994 Chen NH, Reith MEA. Effects of locally applied cocaine, lidocaine, and various uptake blockers on monoamine transmission in the ventral tegmental area of freely moving rats: A microdialysis study on monoamine interrelationships Journal of Neurochemistry. 63: 1701-1713. PMID 7931325  0.96
1994 Chen NH, Wang C, Jobe PC, Reith ME. Facilitation of amygdala kindling development and kindled seizures by metaphit. Epilepsia. 35: 927-32. PMID 7925163 DOI: 10.1111/j.1528-1157.1994.tb02536.x  0.96
1993 Reith MEA, Coffey LL. Cationic and anionic requirements for the binding of 2β-carbomethoxy-3β-(4-fluorophenyl)[3H]tropane to the dopamine uptake carrier Journal of Neurochemistry. 61: 167-177. PMID 8515263  0.96
1993 Chen NH, Reith MEA. Dopamine and serotonin release-regulating autoreceptor sensitivity in A9/A10 cell body and terminal areas after withdrawal of rats from continuous infusion of cocaine Journal of Pharmacology and Experimental Therapeutics. 267: 1445-1453. PMID 8263807  0.96
1993 Chen NH, Reith MEA. [3H]dopamine and [3H]serotonin release in vitro induced by electrical stimulation in A9 and A10 dopamine regions of rat brain: Characterization and responsiveness to cocaine Journal of Pharmacology and Experimental Therapeutics. 267: 379-389. PMID 8229765  0.96
1992 Wiener HL, Reith MEA. Determination of radioligand specific activity using competition binding assays Analytical Biochemistry. 207: 58-62. PMID 1489100 DOI: 10.1016/0003-2697(92)90499-W  0.96
1991 Debler EA, Sershen H, Hashim A, Lajtha A, Reith ME. Carrier-mediated efflux of [3H]dopamine and [3H]1-methyl-4-phenylpyridine: effect of ascorbic acid. Synapse (New York, N.Y.). 7: 99-105. PMID 2011830 DOI: 10.1002/syn.890070203  1
1990 Reith ME, Kramer HK, Sershen H, Lajtha A. D-tartrate alters uptake of [3H]dopamine into brain synaptic vesicles. Journal of Neuroscience Methods. 31: 133-6. PMID 2319813  0.44
1989 Benuck M, Reith ME, Sershen H, Wiener HL, Lajtha A. Oxidative metabolism of cocaine: comparison of brain and liver. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 190: 7-13. PMID 2911610  0.6
1989 Kramer HK, Sershen H, Lajtha A, Reith ME. The effect of nicotine on catecholaminergic storage vesicles. Brain Research. 503: 296-8. PMID 2605521  0.44
1988 Sershen H, Berger P, Jacobson AE, Rice KC, Reith ME. Metaphit prevents locomotor activation induced by various psychostimulants and interferes with the dopaminergic system in mice. Neuropharmacology. 27: 23-30. PMID 3352864  0.44
1987 Sershen H, Banay-Schwartz M, Dunlop DS, Debler EA, Reith ME. Nicotine-induced changes in the metabolism of specific brain proteins. Neurochemical Research. 12: 197-202. PMID 3574595  0.44
1987 Reith MEA, Sershen H, Lajtha A. Effects of caffeine on monoaminergic systems in mouse brain Acta Biochimica Et Biophysica Hungarica. 22: 149-163. PMID 2823512  0.96
1986 Reith ME, Meisler BE, Sershen H, Lajtha A. Structural requirements for cocaine congeners to interact with dopamine and serotonin uptake sites in mouse brain and to induce stereotyped behavior. Biochemical Pharmacology. 35: 1123-9. PMID 3964292  0.44
1986 Reith MEA, Sershen H, Lajtha A. Binding Sites for [3H]Cocaine in Mouse Striatum and Cerebral Cortex Have Different Dissociation Kinetics Journal of Neurochemistry. 46: 309-312. PMID 3940290 DOI: 10.1111/j.1471-4159.1986.tb12966.x  0.96
1986 Sershen H, Mason MF, Reith ME, Hashim A, Lajtha A. Effect of nicotine and amphetamine on the neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mice. Neuropharmacology. 25: 1231-4. PMID 3491964  1
1986 Sershen H, Mason MF, Reith ME, Hashim A, Lajtha A. Effect of amphetamine on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in mice. Neuropharmacology. 25: 927-30. PMID 3490630  1
1985 Reith ME, Meisler BE, Sershen H, Lajtha A. Sodium-independent binding of [3H]cocaine in mouse striatum is serotonin related. Brain Research. 342: 145-8. PMID 4041805  0.44
1985 Sershen H, Reith ME, Hashim A, Lajtha A. Comparison of [3H]nicotine and [3H]acetylcholine binding in mouse brain: regional distribution. Research Communications in Chemical Pathology and Pharmacology. 48: 345-52. PMID 4023418  1
1985 Sershen H, Reith ME, Hashim A, Lajtha A. Protection against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity by the antioxidant ascorbic acid. Neuropharmacology. 24: 1257-9. PMID 3879338  1
1984 Reith ME, Allen DL, Sershen H, Lajtha A. Similarities and differences between high-affinity binding sites for cocaine and imipramine in mouse cerebral cortex. Journal of Neurochemistry. 43: 249-55. PMID 6726250  0.44
1984 Reith ME, Meisler BE, Sershen H, Lajtha A. [3H]cocaine binding in brain is inhibited by Tris (hydroxymethyl) aminomethane. Journal of Neuroscience Methods. 12: 151-4. PMID 6527554  0.44
1984 Sershen H, Reith ME, Hashim A, Lajtha A. Endogenous material in brain inhibiting [3H]nicotine and [3H]acetylcholine binding. Journal of Neuroscience Research. 12: 563-9. PMID 6512887 DOI: 10.1002/jnr.490120405  1
1984 Reith MEA, Sershen H, Lajtha A. Binding of imipramine and cocaine to a model lipid membrane - Comparison with binding to brain membranes Neurochemical Research. 9: 965-977. PMID 6504231 DOI: 10.1007/BF00964527  0.96
1984 Sershen H, Reith ME, Hashim A, Lajtha A. Reduction of dopamine uptake and cocaine binding in mouse striatum by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. European Journal of Pharmacology. 102: 175-8. PMID 6332738  1
1984 Reith MEA, Sershen H, Lajtha A. Thermodynamics of the interactions of tricyclic drugs with binding sites for [3H]imipramine in mouse cerebral cortex Biochemical Pharmacology. 33: 4101-4104. PMID 6095869 DOI: 10.1016/0006-2952(84)90030-3  0.96
1983 Reith ME, Sershen H, Allen DL, Lajtha A. A portion of [3H]cocaine binding in brain is associated with serotonergic neurons. Molecular Pharmacology. 23: 600-6. PMID 6865907  0.44
1983 Reith ME, Sershen H, Allen D, Lajtha A. High- and low-affinity binding of [3H]imipramine in mouse cerebral cortex. Journal of Neurochemistry. 40: 389-95. PMID 6296317  0.44
1983 Allen DL, Reith ME, Sershen H, Lajtha A. Imipramine does not act as a false transmitter in the rat hypothalamus. Brain Research. 267: 161-4. PMID 6134569  0.44
1982 Sershen H, Reith MEA, Lajtha A. On the interaction between nicotine and cycloheximide Brain Research. 251: 183-185. PMID 7172004 DOI: 10.1016/0006-8993(82)91290-2  0.96
1982 Sershen H, Reith ME, Banay-Schwartz M, Lajtha A. Effects of prenatal administration of nicotine on amino acid pools, protein metabolism, and nicotine binding in the brain. Neurochemical Research. 7: 1515-22. PMID 7170065  0.44
1982 Sershen H, Reith MEA, Lajtha A. Comparison of the properties of central and peripheral binding sites for cocaine Neuropharmacology. 21: 469-474. PMID 6287333 DOI: 10.1016/0028-3908(82)90033-8  0.96
1981 Reith MEA, Sershen H, Lajtha A. Binding of [3h] cocaine in mouse brain: Kinetics and saturability Journal of Receptors and Signal Transduction. 2: 233-243. PMID 7334483 DOI: 10.3109/10799898109038802  0.96
1981 Sershen H, Reith ME, Lajtha A, Gennaro J. Noncholinergic, saturable binding of (+/-)-[3H]nicotine to mouse brain. Journal of Receptor Research. 2: 1-15. PMID 7288742  0.44
1981 Sershen H, Reith ME, Lajtha A, Gennaro J. Effect of cigarette smoke on protein synthesis in brain and liver. Neuropharmacology. 20: 451-6. PMID 7242865  0.44
1981 Reith ME, Sershen H, Vadasz C, Lajtha A. Strain differences in opiate receptors in mouse brain. European Journal of Pharmacology. 74: 377-80. PMID 6271560  0.44
1980 Sershen H, Reith MEA, Lajtha A. The pharmacological relevance of the cocaine binding site in mouse brain Neuropharmacology. 19: 1145-1148. PMID 7442945 DOI: 10.1016/0028-3908(80)90116-1  0.96
1980 Reith MEA, Sershen H, Lajtha A. Endogenous peptide(s) inhibiting [3H]cocaine binding in mouse brain Neurochemical Research. 5: 1291-1299. PMID 6261176 DOI: 10.1007/BF00964964  0.96
1980 Reith MEA, Sershen H, Lajtha A. Saturable (3H)cocaine binding in central nervous system of mouse Life Sciences. 27: 1055-1062. PMID 6106874 DOI: 10.1016/0024-3205(80)90029-6  0.96
1979 Reith ME, Schotman P, van Zwieten BJ, Gispen WH. The nature of the amino acid pool used for protein synthesis in rat brain slices. Journal of Neurochemistry. 32: 413-20. PMID 762556  1
1978 Reith ME, Schotman P, Gispen WH. Measurements of in vivo rates of protein synthesis in brain, spinal cord, heart and liver of young versus adult rats, intact versus hypophysectomized rats. Journal of Neurochemistry. 30: 587-94. PMID 681932  1
1977 Schotman P, Reith ME, Gispen WH. Effects of stressful procedures as ether anesthesia and intracranial injections on amino acid incorporation into brain protein. Brain Research Bulletin. 2: 83-7. PMID 880489  1
1977 Gispen WH, Reith ME, Schotman P, Wiegant VM, Zwiers H, de Wied D. CNS and ACTH-like peptides: neurochemical response and interaction with opiates. Advances in Biochemical Psychopharmacology. 17: 61-80. PMID 200081  0.96
1975 Reith ME, Schotman P, Gispen WH. The neurotropic action of ACTH: effects of ACTH-like peptides on the incorporation of leucine into protein of brain stem slices from hypophysectomized rats. Neuroscience Letters. 1: 55-9. PMID 19604752  1
1975 Reith ME, Schotman P, Gispen WH. Incorporation of [3H] leucine into brain stem protein fractions: the effect of a behaviorally active, N-terminal fragment of ACTH in hypophysectomized rats. Neurobiology. 5: 355-68. PMID 174020  1
1975 Reith ME, Schotman P, Gispen WH. Effects of behaviorally active ACTH analogs on brain protein metabolism. Progress in Brain Research. 42: 195-200. PMID 172963 DOI: 10.1016/S0079-6123(08)63660-2  1
1974 Reith ME, Schotman P, Gispen WH. Hypophysectomy, ACTH1-10 and in vitro protein synthesis in rat brain stem slices. Brain Research. 81: 571-5. PMID 4373137  1
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